2Y2DA

Crystal structure of ampd holoenzyme
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
179
structure length
179
Chain Sequence
MLLDEGWLAEARRVPSPHYDCRPDDENPSLLVVHNISLPPGEFGGPWIDALFTGTIDPNAHPYFAGIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSSYQGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTNALITRYPAIANNMTGHCNIAPERKTDPGPSFDWARFRALVT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Bacterial Peptidoglycan Amidase Ampd and an Unprecedented Activation Mechanism.
pubmed doi rcsb
molecule keywords 1,6-ANHYDRO-N-ACETYLMURAMYL-L-ALANINE AMIDASE AMPD
molecule tags Hydrolase
source organism Citrobacter freundii
total genus 55
structure length 179
sequence length 179
chains with identical sequence B, C
ec nomenclature ec 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
pdb deposition date 2010-12-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01510 Amidase_2 N-acetylmuramoyl-L-alanine amidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.80.10 Alpha Beta 3-Layer(aba) Sandwich Lysozyme-like Peptidoglycan recognition protein-like 2y2dA00
3QV4A 4Z8IA 4IVVA 2AR3A 3NG4A 4KNKA 1TWQA 4ZXMA 4Q9EA 2RKQA 3T2VA 3USXA 3D2YA 2XZ4A 3O4KA 4BXJA 2F2LA 4OUGA 1SK3A 3UMLA 1YB0A 3C2XA 5DWFA 3RDRA 3QS0A 2R90A 2L47A 1YCKA 2Y2BA 2WKXA 2Y2EA 1J3GA 3CXAA 4KNLA 3T39A 1SK4A 1LBAA 3CG9A 4BXDA 2Y2DA 2EAVA 1SXRA 4ORVA 4Q8SA 4OPPA 3NW3A 4BXEA 1Z6IA 3D2ZA 2XZ8A 4GF9A 3QJ1A 4OLSA 3OGXA 1AROL 4BOLA 2Y28A 4X36A 3NNOA 5CTVA 2BH7A 1S2JA 1OHTA 3TRUA 4BPAA 5E0AA 3RT4A 2F2LX 3HMBA 2Z9NA 4BJ4A 3UMQA 2APHA 4FNNA 3CORA 2EAXA 5E0BA 2Y2CA 3EP1A 2R2KA 2CB3A 3UILA 3LATA
chains in the Genus database with same CATH superfamily
3QV4A 4Z8IA 4IVVA 2AR3A 3NG4A 4KNKA 1TWQA 4ZXMA 4Q9EA 2RKQA 3T2VA 3USXA 3D2YA 2XZ4A 3O4KA 4BXJA 2F2LA 4OUGA 1SK3A 3UMLA 1YB0A 3C2XA 5DWFA 3RDRA 3QS0A 2R90A 2L47A 1YCKA 2Y2BA 2WKXA 2Y2EA 1J3GA 3CXAA 4KNLA 3T39A 1SK4A 1LBAA 3CG9A 4BXDA 2Y2DA 2EAVA 1SXRA 4ORVA 4Q8SA 4OPPA 3NW3A 4BXEA 1Z6IA 3D2ZA 2XZ8A 4GF9A 3QJ1A 4OLSA 3OGXA 1AROL 4BOLA 2Y28A 4X36A 3NNOA 5CTVA 2BH7A 1S2JA 1OHTA 3TRUA 4BPAA 5E0AA 3RT4A 2F2LX 3HMBA 2Z9NA 4BJ4A 3UMQA 2APHA 4FNNA 3CORA 2EAXA 5E0BA 2Y2CA 3EP1A 2R2KA 2CB3A 3UILA 3LATA
chains in the Genus database with same CATH topology
3QV4A 4Z8IA 4IVVA 2AR3A 3NG4A 4KNKA 1TWQA 4ZXMA 4Q9EA 2RKQA 3T2VA 3USXA 3D2YA 2XZ4A 3O4KA 4BXJA 2F2LA 4OUGA 1SK3A 3UMLA 1YB0A 3C2XA 5DWFA 3RDRA 3QS0A 2R90A 2L47A 1YCKA 2Y2BA 2WKXA 2Y2EA 1J3GA 3CXAA 4KNLA 3T39A 1SK4A 1LBAA 3CG9A 4BXDA 2Y2DA 2EAVA 1SXRA 4ORVA 4Q8SA 4OPPA 3NW3A 4BXEA 1Z6IA 3D2ZA 2XZ8A 4GF9A 3QJ1A 4OLSA 3OGXA 1AROL 4BOLA 2Y28A 4X36A 3NNOA 5CTVA 2BH7A 1S2JA 1OHTA 3TRUA 4BPAA 5E0AA 3RT4A 2F2LX 3HMBA 2Z9NA 4BJ4A 3UMQA 2APHA 4FNNA 3CORA 2EAXA 5E0BA 2Y2CA 3EP1A 2R2KA 2CB3A 3UILA 3LATA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QV4 A;  4Z8I A;  4IVV A;  2AR3 A;  3NG4 A;  4KNK A;  1TWQ A;  4ZXM A;  4Q9E A;  2RKQ A;  3T2V A;  3USX A;  3D2Y A;  2XZ4 A;  3O4K A;  4BXJ A;  2F2L A;  4OUG A;  1SK3 A;  3UML A;  1YB0 A;  3C2X A;  5DWF A;  3RDR A;  3QS0 A;  2R90 A;  2L47 A;  1YCK A;  2Y2B A;  2WKX A;  2Y2E A;  1J3G A;  3CXA A;  4KNL A;  3T39 A;  1SK4 A;  1LBA A;  3CG9 A;  4BXD A;  2Y2D A;  2EAV A;  1SXR A;  4ORV A;  4Q8S A;  4OPP A;  3NW3 A;  4BXE A;  1Z6I A;  3D2Z A;  2XZ8 A;  4GF9 A;  3QJ1 A;  4OLS A;  3OGX A;  1ARO L;  4BOL A;  2Y28 A;  4X36 A;  3NNO A;  5CTV A;  2BH7 A;  1S2J A;  1OHT A;  3TRU A;  4BPA A;  5E0A A;  3RT4 A;  2F2L X;  3HMB A;  2Z9N A;  4BJ4 A;  3UMQ A;  2APH A;  4FNN A;  3COR A;  2EAX A;  5E0B A;  2Y2C A;  3EP1 A;  2R2K A;  2CB3 A;  3UIL A;  3LAT A; 
#chains in the Genus database with same CATH topology
 3QV4 A;  4Z8I A;  4IVV A;  2AR3 A;  3NG4 A;  4KNK A;  1TWQ A;  4ZXM A;  4Q9E A;  2RKQ A;  3T2V A;  3USX A;  3D2Y A;  2XZ4 A;  3O4K A;  4BXJ A;  2F2L A;  4OUG A;  1SK3 A;  3UML A;  1YB0 A;  3C2X A;  5DWF A;  3RDR A;  3QS0 A;  2R90 A;  2L47 A;  1YCK A;  2Y2B A;  2WKX A;  2Y2E A;  1J3G A;  3CXA A;  4KNL A;  3T39 A;  1SK4 A;  1LBA A;  3CG9 A;  4BXD A;  2Y2D A;  2EAV A;  1SXR A;  4ORV A;  4Q8S A;  4OPP A;  3NW3 A;  4BXE A;  1Z6I A;  3D2Z A;  2XZ8 A;  4GF9 A;  3QJ1 A;  4OLS A;  3OGX A;  1ARO L;  4BOL A;  2Y28 A;  4X36 A;  3NNO A;  5CTV A;  2BH7 A;  1S2J A;  1OHT A;  3TRU A;  4BPA A;  5E0A A;  3RT4 A;  2F2L X;  3HMB A;  2Z9N A;  4BJ4 A;  3UMQ A;  2APH A;  4FNN A;  3COR A;  2EAX A;  5E0B A;  2Y2C A;  3EP1 A;  2R2K A;  2CB3 A;  3UIL A;  3LAT A; 
#chains in the Genus database with same CATH homology
 3QV4 A;  4Z8I A;  4IVV A;  2AR3 A;  3NG4 A;  4KNK A;  1TWQ A;  4ZXM A;  4Q9E A;  2RKQ A;  3T2V A;  3USX A;  3D2Y A;  2XZ4 A;  3O4K A;  4BXJ A;  2F2L A;  4OUG A;  1SK3 A;  3UML A;  1YB0 A;  3C2X A;  5DWF A;  3RDR A;  3QS0 A;  2R90 A;  2L47 A;  1YCK A;  2Y2B A;  2WKX A;  2Y2E A;  1J3G A;  3CXA A;  4KNL A;  3T39 A;  1SK4 A;  1LBA A;  3CG9 A;  4BXD A;  2Y2D A;  2EAV A;  1SXR A;  4ORV A;  4Q8S A;  4OPP A;  3NW3 A;  4BXE A;  1Z6I A;  3D2Z A;  2XZ8 A;  4GF9 A;  3QJ1 A;  4OLS A;  3OGX A;  1ARO L;  4BOL A;  2Y28 A;  4X36 A;  3NNO A;  5CTV A;  2BH7 A;  1S2J A;  1OHT A;  3TRU A;  4BPA A;  5E0A A;  3RT4 A;  2F2L X;  3HMB A;  2Z9N A;  4BJ4 A;  3UMQ A;  2APH A;  4FNN A;  3COR A;  2EAX A;  5E0B A;  2Y2C A;  3EP1 A;  2R2K A;  2CB3 A;  3UIL A;  3LAT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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