2Y7XB

The discovery of potent and long-acting oral factor xa inhibitors with tetrahydroisoquinoline and benzazepine p4 motifs
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs.
pubmed doi rcsb
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
molecule tags Blood clotting
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2011-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00008 EGF EGF-like domain
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2y7xB00
4ZXYL 2G00L 1UZPA 3TZIA 2BQWA 5CKNA 2KB9A 2W86A 4BTUA 1HJ7A 2FD6A 1HAEA 4OTYA 3TGFA 5CISA 2KL7A 2YGOA 3NTGA 2WPKE 1EPJA 3FCSB 3KL6B 3M36L 1L3YA 3P5BL 3V65B 2W2ME 2PR3B 1NFYB 3V64C 4Y7BB 4NA9L 3FFGL 3SW2A 3PGHA 4X8UL 1PFXL 1KLIL 3GCXE 4OTJA 2VH0B 2Y5HL 1EPGA 1FE2A 1IJQA 5JB9E 1CCFA 1EBVA 1WHEA 3HO3A 1BF9A 2BZ6L 3HS7A 4RUTA 1EMNA 1Z6CA 1DDXA 2Y38A 4AQTA 1FJSL 3U73A 3KCGL 2YGPA 1UZKA 5L2YL 3N8WA 1CCVA 3F1SB 2J95B 1U8CB 6COXA 3SOQA 1HREA 4Y71B 2BOUA 1I0UA 4XL1A 3TK5B 1EMOA 4JYVL 3NT1A 1PXXA 4E1GA 2I9AA 5IKTA 1ADXA 2BQ6A 3Q7DA 4BXSA 2BOHA 1XDTR 3R05A 3HPTA 1C5MF 1YGCL 5E8DA 2W3IB 4MMXB 2P3FN 3QCWA 2VJ3A 4ISHL 1APQA 1EGFA 3N8YB 1LQDA 3MQEA 2P93L 1LMJA 3ASIA 3TH3L 1EQGA 2BOKL 2WG4B 1CVWL 1G1RA 4M11A 4D90A 4YZUB 1NFUB 5KIRA 4ZHAB 2UWLB 2FLBL 1KLOA 2XBWL 3POYA 5JBAE 4LORA 1OB1C 2BQ7A 3OLUA 2VH6B 4MMYB 1XKBA 3GCWE 1NQLB 2MGRA 2P94L 2WPJE 4A7IA 3LN0A 1O5DL 4Y79B 5CKQA 3BT2A 1F7EA 3N8XA 4RRYA 4ZXXL 1TPGA 2XBXL 3Q3KB 4G1MB 1RFNB 1N7DA 1G2LB 4Z0KB 5KN5C 1EPIA 1TLEA 1YUKB 2PHBB 3HO4A 4NG9L 1TOZA 1IQEL 4CSYA 2CJIB 4M10A 3HO5A 2P3FL 5FDQA 4YT7L 1LPZA 2XC5L 4RRWA 2W3KB 2BO2A 4JZDL 4C16A 1F7MA 5IKRA 1AUTL 1P0SL 1FAXL 2XC0L 2WPME 3OLTA 1EPHA 3BPSE 2P3TA 1IQNL 5L30L 1B9WA 2EI8B 1JL9A 1HZ8A 1W8BL 2PUQL 1KIGL 2GD4A 2H9EL 1F0SB 2WPHE 2J4IB 4RRZA 1LPGA 2RNLA 3HS6A 1IP0A 1ATBA 1MQ6L 5K0HB 1IOEL 2D1JB 2K2TA 1KLJL 1LPKA 2XBYL 5IKVA 1IVOC 1NT0A 2VWNL 1UZJA 2NPRA 3DEMA 1YO8A 2W2QE 5EGMB 1UZQA 3K9XA 2RHPA 3TBDA 3CFWA 1A3PA 4FM5A 3ZYGA 3NJPC 1PTHA 1WHFA 2W2OE 2VWLL 2WG3C 2I9BA 5F1AA 3KK6A 2FLGA 3HS5A 5JVZA 4ZH8B 2FZZL 1M1XB 3KQDL 1NFWB 2WPLE 2DDUA 4CUEA 3KQBL 3QMOA 1HRFA 1SZBA 4BXWA 1HAFA 3KRKA 3LC3B 2WFXB 2J34B 3ZYIB 1HCGB 3IITB 2MHPA 4Y7AB 2KV4A 3LTFB 5F19A 5JVYA 3N8ZA 4BDXA 3N8WB 4JZFL 1L5GB 1G1QA 2EI7B 2XBVL 3LAQA 4ISIL 3MDLA 2B7DL 3C9AC 1NZIA 1XKAL 3M37L 5CKMA 1APOA 2W2NE 2OYEP 2Q1JB 4X8VL 1HX2A 2Y5FL 2P3UA 2W26B 2VVCK 1FFMA 1V3XB 4O02B 4RRXA 2WYJB 1EQHA 2P95L 3KQEL 4Y76B 1P9JA 2P16L 5COXA 2F9BL 4X8SL 4YT6L 1JV2B 2VWMK 2Y81B 1J9CL 2Y7XB 4XBMA 1HT5A 2Y7ZB 1HT8A 1EAIC 2J38B 3TK6B 3EGFA 2AYLA 1ATAA 4TGFA 1N1IA 1U67A 1CEJA 2Y80B 3N8YA 1FSBA 1ATDA 1NFXB 1IQJL 1URKA 1G1SA 4JZEL 1W7XL 2OYUP 3CA7A 4MMZB 1FF7A 1DIYA 1DVAL 1QFKL 1IQGL 3LC5B 1YUFA 2J2UB 2BMGA 1ZAQA 3RR3A 2Y82B 2ADXA 1IQFL 4ZAEB 3ZYJB 4O1ZA 2W2PE 4Z6AL 3N8VA 1DX5I 3BT1A 4CUDA 1Q4GA 2WPIE 3IJEB 1NPEB 1K37A 1MQ5L 2BOXA 1ATEA 4PH9A 1EZQB 1JBUL 3H5CB 4XLWA 4CUFA 3SOVA 5IKQA 1GK5A 3QH0A 1F0RB 2Y5GL 3U7UG 2J94B 3LTGD 1FAKL 5JBCE 2VVVL 1G1TA 2UWPB 2P28B 4Y6DB 2TGFA 4BTTA 4X8TL 1XFEA 2RA0L 5JB8E 1CX2A 2FLRL 5I46L 1CVUA 1KSNB 1G2MB 1IGZA 4NGAL 3ELAL 1K36A 3CS7L 3SOBB 1CQEA 1X7AL 4COXA 1DQBA 4JYUL 4BDWA 4BTIA 2P26A 2WFTA 5L2ZL 1IQIL 4RS0A 3LIWB 1IQHL 1PGEA 2MGPA 3GISX 2WYGB 4D0EA 1PRHA 1IQML 2VVUL 3CENL 1YUGA 4Z0LA 2VWOL 3ENSA 1COUA 3NTBA 1MOXC 5JBBE 4D0FA 3KQCL 1WU1B 2M74A 1IOXA 1Z6EL 2EI6B 2UWOB 1IQKL 4LMFA 2JKHL 1IQLL 3LN1A 3F6UL 3FBYA 1IGXA 2XC4L 5JW1A 2K2SB
chains in the Genus database with same CATH superfamily
4ZXYL 2G00L 1UZPA 3S6XA 1LK9A 3TZIA 2BQWA 5CKNA 2KB9A 2W86A 4BTUA 1HJ7A 2FD6A 1HAEA 4OTYA 3TGFA 5CISA 2KL7A 2YGOA 3NTGA 2WPKE 1EPJA 3FCSB 3KL6B 3M36L 1L3YA 3P5BL 3V65B 2W2ME 2PR3B 1NFYB 3V64C 4Y7BB 2BT7A 4NA9L 1QIUA 3FFGL 3SW2A 3PGHA 4X8UL 1PFXL 1KLIL 3GCXE 4OTJA 2VH0B 2Y5HL 1EPGA 1FE2A 1IJQA 5JB9E 1CCFA 1EBVA 1WHEA 3HO3A 1BF9A 2BZ6L 3HS7A 4RUTA 1EMNA 1Z6CA 1DDXA 2Y38A 4AQTA 1FJSL 3U73A 3KCGL 2YGPA 1UZKA 5L2YL 3N8WA 1CCVA 3F1SB 2J95B 1U8CB 6COXA 2KNIA 3SOQA 1HREA 4Y71B 2BOUA 1I0UA 4XL1A 3TK5B 1EMOA 4JYVL 3NT1A 1PXXA 4E1GA 2I9AA 5IKTA 1ADXA 1KKEA 2BQ6A 3Q7DA 4BXSA 2BOHA 1XDTR 3R05A 3HPTA 1C5MF 1YGCL 5E8DA 2W3IB 4MMXB 2P3FN 3QCWA 2VJ3A 4ISHL 1APQA 1EGFA 3N8YB 1LQDA 3MQEA 2P93L 1LMJA 3ASIA 3TH3L 1EQGA 2BOKL 2WG4B 1CVWL 2H9EC 1G1RA 4M11A 4D90A 4YZUB 1NFUB 5KIRA 2HORA 4ZHAB 2UWLB 2FLBL 1KLOA 2XBWL 3POYA 5JBAE 4LORA 1OB1C 2BQ7A 3OLUA 2VH6B 4MMYB 1XKBA 2WZPP 3GCWE 1NQLB 2MGRA 2P94L 2WPJE 4A7IA 3LN0A 1O5DL 4Y79B 5CKQA 3BT2A 1F7EA 3N8XA 4RRYA 4ZXXL 1TPGA 2XBXL 3Q3KB 4G1MB 1RFNB 1N7DA 1G2LB 4Z0KB 5KN5C 1EPIA 1TLEA 1YUKB 2PHBB 3HO4A 4NG9L 1TOZA 1IQEL 4CSYA 2CJIB 4M10A 3HO5A 2P3FL 5FDQA 4YT7L 1LPZA 2XC5L 4RRWA 2W3KB 2BO2A 4GU3A 4JZDL 4C16A 1F7MA 5IKRA 1AUTL 1P0SL 1FAXL 2XC0L 2WPME 3OLTA 1EPHA 3BPSE 2P3TA 1IQNL 5L30L 1B9WA 2EI8B 1JL9A 1HZ8A 1W8BL 2PUQL 1KIGL 2GD4A 2H9EL 1F0SB 2JJLA 2WPHE 2J4IB 4RRZA 1LPGA 2RNLA 3HS6A 1IP0A 1ATBA 1MQ6L 5K0HB 1IOEL 2D1JB 2K2TA 1KLJL 1LPKA 2XBYL 1LMMA 5IKVA 1IVOC 1NT0A 2VWNL 1UZJA 2NPRA 3DEMA 1YO8A 2W2QE 5EGMB 1UZQA 3K9XA 2RHPA 3TBDA 3CFWA 1A3PA 4FM5A 3ZYGA 3NJPC 1PTHA 1WHFA 2W2OE 2VWLL 2WG3C 2I9BA 5F1AA 3KK6A 2FLGA 3HS5A 5JVZA 4ZH8B 2FZZL 1M1XB 3KQDL 1NFWB 2WPLE 2DDUA 4CUEA 3KQBL 3QMOA 1HRFA 1SZBA 4BXWA 1HAFA 3KRKA 3LC3B 2WFXB 2J34B 3ZYIB 4A94C 1HCGB 3IITB 2BSFA 2MHPA 4Y7AB 2KV4A 3LTFB 5F19A 5JVYA 3N8ZA 4BDXA 3N8WB 4JZFL 1L5GB 1G1QA 2EI7B 2XBVL 3LAQA 4ISIL 3MDLA 2B7DL 3C9AC 1NZIA 1XKAL 3M37L 5CKMA 1APOA 2W2NE 2OYEP 2Q1JB 4X8VL 1HX2A 2Y5FL 2P3UA 2W26B 2YGQA 2VVCK 1FFMA 1V3XB 4O02B 4RRXA 2WYJB 1EQHA 2P95L 3KQEL 4Y76B 1P9JA 2P16L 5COXA 2F9BL 4X8SL 4YT6L 4GU4A 1JV2B 2VWMK 2Y81B 1J9CL 2Y7XB 4XBMA 1V1HA 1HT5A 2Y7ZB 1HT8A 1EAIC 2J38B 3TK6B 3EGFA 2AYLA 1ATAA 4TGFA 1N1IA 1U67A 1CEJA 2Y80B 3N8YA 1FSBA 1ATDA 1NFXB 1IQJL 1URKA 2HOXA 1G1SA 4JZEL 1W7XL 2OYUP 3CA7A 4MMZB 1FF7A 1DIYA 1DVAL 2VRSA 1QFKL 1IQGL 3LC5B 1YUFA 2J2UB 2BMGA 1ZAQA 3RR3A 2Y82B 2ADXA 1IQFL 4ZAEB 3ZYJB 4O1ZA 2W2PE 4Z6AL 3N8VA 1DX5I 3BT1A 4CUDA 1Q4GA 2WPIE 3IJEB 1NPEB 1K37A 1MQ5L 2BOXA 1ATEA 4PH9A 1EZQB 1JBUL 3H5CB 4XLWA 4CUFA 3SOVA 5IKQA 1GK5A 3QH0A 1F0RB 2Y5GL 3U7UG 2J94B 3LTGD 1FAKL 5JBCE 2VVVL 1G1TA 2UWPB 2P28B 4Y6DB 2TGFA 4BTTA 4X8TL 1XFEA 2RA0L 5JB8E 1CX2A 2FLRL 5I46L 1CVUA 1KSNB 1G2MB 1IGZA 4NGAL 3ELAL 1K36A 3CS7L 3SOBB 1CQEA 1X7AL 4COXA 1DQBA 4JYUL 4BDWA 4BTIA 2P26A 2WFTA 5L2ZL 1IQIL 4RS0A 3LIWB 1IQHL 1PGEA 2MGPA 3GISX 2WYGB 4D0EA 1PRHA 1IQML 2BT8A 2VVUL 3CENL 1YUGA 4Z0LA 2VWOL 3ENSA 1V1IA 1COUA 3NTBA 1MOXC 5JBBE 4D0FA 3KQCL 1WU1B 2M74A 1IOXA 1Z6EL 2EI6B 2UWOB 1IQKL 4LMFA 2JKHL 1IQLL 3LN1A 3F6UL 3FBYA 1IGXA 2XC4L 5JW1A 2K2SB
chains in the Genus database with same CATH topology
4ZXYL 2G00L 1UZPA 3S6XA 3TZIA 2BQWA 5CKNA 2KB9A 2W86A 4BTUA 1HJ7A 2FD6A 1HAEA 4OTYA 3TGFA 5CISA 2KL7A 2YGOA 3NTGA 2WPKE 1EPJA 3FCSB 3KL6B 3M36L 1L3YA 3P5BL 3V65B 2W2ME 2PR3B 1NFYB 3V64C 4Y7BB 4NA9L 3FFGL 3SW2A 3PGHA 4X8UL 1PFXL 1KLIL 3GCXE 4OTJA 2VH0B 2Y5HL 1EPGA 1FE2A 1IJQA 5JB9E 1CCFA 1EBVA 1WHEA 3HO3A 1BF9A 2BZ6L 3HS7A 4RUTA 1EMNA 1Z6CA 1DDXA 2Y38A 4AQTA 1FJSL 3U73A 3KCGL 2YGPA 1UZKA 5L2YL 3N8WA 1CCVA 3F1SB 2J95B 1U8CB 6COXA 2KNIA 3SOQA 1HREA 4Y71B 2BOUA 1I0UA 4XL1A 3TK5B 1EMOA 4JYVL 3NT1A 1PXXA 4E1GA 2I9AA 5IKTA 1ADXA 2BQ6A 3Q7DA 4BXSA 2BOHA 1XDTR 3R05A 3HPTA 1C5MF 1YGCL 5E8DA 2W3IB 4MMXB 2P3FN 3QCWA 2VJ3A 4ISHL 1APQA 1EGFA 3N8YB 1LQDA 3MQEA 2P93L 1LMJA 3ASIA 3TH3L 1EQGA 2BOKL 2WG4B 1CVWL 2H9EC 1G1RA 4M11A 4D90A 4YZUB 1NFUB 5KIRA 4ZHAB 2UWLB 2FLBL 1KLOA 2XBWL 3POYA 5JBAE 4LORA 1OB1C 2BQ7A 3OLUA 2VH6B 4MMYB 1XKBA 2WZPP 3GCWE 1NQLB 2MGRA 2P94L 2WPJE 4A7IA 3LN0A 1O5DL 4Y79B 5CKQA 3BT2A 1F7EA 3N8XA 4RRYA 4ZXXL 1TPGA 2XBXL 3Q3KB 4G1MB 1RFNB 1N7DA 1G2LB 4Z0KB 5KN5C 1EPIA 1TLEA 1YUKB 2PHBB 3HO4A 4NG9L 1TOZA 1IQEL 4CSYA 2CJIB 4M10A 3HO5A 2P3FL 5FDQA 4YT7L 1LPZA 2XC5L 4RRWA 2W3KB 2BO2A 4JZDL 4C16A 1F7MA 5IKRA 1AUTL 1P0SL 1FAXL 2XC0L 2WPME 3OLTA 1EPHA 3BPSE 2P3TA 1IQNL 5L30L 1B9WA 2EI8B 1JL9A 1HZ8A 1W8BL 2PUQL 1KIGL 2GD4A 2H9EL 1F0SB 2WPHE 2J4IB 4RRZA 1LPGA 2RNLA 3HS6A 1IP0A 1ATBA 1MQ6L 5K0HB 1IOEL 2D1JB 2K2TA 1KLJL 1LPKA 2XBYL 1LMMA 5IKVA 1IVOC 1NT0A 2VWNL 1UZJA 2NPRA 3DEMA 1YO8A 2W2QE 5EGMB 1UZQA 3K9XA 2RHPA 3TBDA 3CFWA 1A3PA 4FM5A 3ZYGA 3NJPC 1PTHA 1WHFA 2W2OE 2VWLL 2WG3C 2I9BA 5F1AA 3KK6A 2FLGA 3HS5A 5JVZA 4ZH8B 2FZZL 1M1XB 3KQDL 1NFWB 2WPLE 2DDUA 4CUEA 3KQBL 3QMOA 1HRFA 1SZBA 4BXWA 1HAFA 3KRKA 3LC3B 2WFXB 2J34B 3ZYIB 4A94C 1HCGB 3IITB 2MHPA 4Y7AB 2KV4A 3LTFB 5F19A 5JVYA 3N8ZA 4BDXA 3N8WB 4JZFL 1L5GB 1G1QA 2EI7B 2XBVL 3LAQA 4ISIL 3MDLA 2B7DL 3C9AC 1NZIA 1XKAL 3M37L 5CKMA 1APOA 2W2NE 2OYEP 2Q1JB 4X8VL 1HX2A 2Y5FL 2P3UA 2W26B 2YGQA 2VVCK 1FFMA 1V3XB 4O02B 4RRXA 2WYJB 1EQHA 2P95L 3KQEL 4Y76B 1P9JA 2P16L 5COXA 2F9BL 4X8SL 4YT6L 1JV2B 2VWMK 2Y81B 1J9CL 2Y7XB 4XBMA 1HT5A 2Y7ZB 1HT8A 1EAIC 2J38B 3TK6B 3EGFA 2AYLA 1ATAA 4TGFA 1N1IA 1U67A 1CEJA 2Y80B 3N8YA 1FSBA 1ATDA 1NFXB 1IQJL 1URKA 1G1SA 4JZEL 1W7XL 2OYUP 3CA7A 4MMZB 1FF7A 1DIYA 1DVAL 1QFKL 1IQGL 3LC5B 1YUFA 2J2UB 2BMGA 1ZAQA 3RR3A 2Y82B 2ADXA 1IQFL 4ZAEB 3ZYJB 4O1ZA 2W2PE 4Z6AL 3N8VA 1DX5I 3BT1A 4CUDA 1Q4GA 2WPIE 3IJEB 1NPEB 1K37A 1MQ5L 2BOXA 1ATEA 4PH9A 1EZQB 1JBUL 3H5CB 4XLWA 4CUFA 3SOVA 5IKQA 1GK5A 3QH0A 1F0RB 2Y5GL 3U7UG 2J94B 3LTGD 1FAKL 5JBCE 2VVVL 1G1TA 2UWPB 2P28B 4Y6DB 2TGFA 4BTTA 4X8TL 1XFEA 2RA0L 5JB8E 1CX2A 2FLRL 5I46L 1CVUA 1KSNB 1G2MB 1IGZA 4NGAL 3ELAL 1K36A 3CS7L 3SOBB 1CQEA 1X7AL 4COXA 1DQBA 4JYUL 4BDWA 4BTIA 2P26A 2WFTA 5L2ZL 1IQIL 4RS0A 3LIWB 1IQHL 1PGEA 2MGPA 3GISX 2WYGB 4D0EA 1PRHA 1IQML 2VVUL 3CENL 1YUGA 4Z0LA 2VWOL 3ENSA 1COUA 3NTBA 1MOXC 5JBBE 4D0FA 3KQCL 1WU1B 2M74A 1IOXA 1Z6EL 2EI6B 2UWOB 1IQKL 4LMFA 2JKHL 1IQLL 3LN1A 3F6UL 3FBYA 1IGXA 2XC4L 5JW1A 2K2SB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZXY L;  2G00 L;  1UZP A;  3TZI A;  2BQW A;  5CKN A;  2KB9 A;  2W86 A;  4BTU A;  1HJ7 A;  2FD6 A;  1HAE A;  4OTY A;  3TGF A;  5CIS A;  2KL7 A;  2YGO A;  3NTG A;  2WPK E;  1EPJ A;  3FCS B;  3KL6 B;  3M36 L;  1L3Y A;  3P5B L;  3V65 B;  2W2M E;  2PR3 B;  1NFY B;  3V64 C;  4Y7B B;  4NA9 L;  3FFG L;  3SW2 A;  3PGH A;  4X8U L;  1PFX L;  1KLI L;  3GCX E;  4OTJ A;  2VH0 B;  2Y5H L;  1EPG A;  1FE2 A;  1IJQ A;  5JB9 E;  1CCF A;  1EBV A;  1WHE A;  3HO3 A;  1BF9 A;  2BZ6 L;  3HS7 A;  4RUT A;  1EMN A;  1Z6C A;  1DDX A;  2Y38 A;  4AQT A;  1FJS L;  3U73 A;  3KCG L;  2YGP A;  1UZK A;  5L2Y L;  3N8W A;  1CCV A;  3F1S B;  2J95 B;  1U8C B;  6COX A;  3SOQ A;  1HRE A;  4Y71 B;  2BOU A;  1I0U A;  4XL1 A;  3TK5 B;  1EMO A;  4JYV L;  3NT1 A;  1PXX A;  4E1G A;  2I9A A;  5IKT A;  1ADX A;  2BQ6 A;  3Q7D A;  4BXS A;  2BOH A;  1XDT R;  3R05 A;  3HPT A;  1C5M F;  1YGC L;  5E8D A;  2W3I B;  4MMX B;  2P3F N;  3QCW A;  2VJ3 A;  4ISH L;  1APQ A;  1EGF A;  3N8Y B;  1LQD A;  3MQE A;  2P93 L;  1LMJ A;  3ASI A;  3TH3 L;  1EQG A;  2BOK L;  2WG4 B;  1CVW L;  1G1R A;  4M11 A;  4D90 A;  4YZU B;  1NFU B;  5KIR A;  4ZHA B;  2UWL B;  2FLB L;  1KLO A;  2XBW L;  3POY A;  5JBA E;  4LOR A;  1OB1 C;  2BQ7 A;  3OLU A;  2VH6 B;  4MMY B;  1XKB A;  3GCW E;  1NQL B;  2MGR A;  2P94 L;  2WPJ E;  4A7I A;  3LN0 A;  1O5D L;  4Y79 B;  5CKQ A;  3BT2 A;  1F7E A;  3N8X A;  4RRY A;  4ZXX L;  1TPG A;  2XBX L;  3Q3K B;  4G1M B;  1RFN B;  1N7D A;  1G2L B;  4Z0K B;  5KN5 C;  1EPI A;  1TLE A;  1YUK B;  2PHB B;  3HO4 A;  4NG9 L;  1TOZ A;  1IQE L;  4CSY A;  2CJI B;  4M10 A;  3HO5 A;  2P3F L;  5FDQ A;  4YT7 L;  1LPZ A;  2XC5 L;  4RRW A;  2W3K B;  2BO2 A;  4JZD L;  4C16 A;  1F7M A;  5IKR A;  1AUT L;  1P0S L;  1FAX L;  2XC0 L;  2WPM E;  3OLT A;  1EPH A;  3BPS E;  2P3T A;  1IQN L;  5L30 L;  1B9W A;  2EI8 B;  1JL9 A;  1HZ8 A;  1W8B L;  2PUQ L;  1KIG L;  2GD4 A;  2H9E L;  1F0S B;  2WPH E;  2J4I B;  4RRZ A;  1LPG A;  2RNL A;  3HS6 A;  1IP0 A;  1ATB A;  1MQ6 L;  5K0H B;  1IOE L;  2D1J B;  2K2T A;  1KLJ L;  1LPK A;  2XBY L;  5IKV A;  1IVO C;  1NT0 A;  2VWN L;  1UZJ A;  2NPR A;  3DEM A;  1YO8 A;  2W2Q E;  5EGM B;  1UZQ A;  3K9X A;  2RHP A;  3TBD A;  3CFW A;  1A3P A;  4FM5 A;  3ZYG A;  3NJP C;  1PTH A;  1WHF A;  2W2O E;  2VWL L;  2WG3 C;  2I9B A;  5F1A A;  3KK6 A;  2FLG A;  3HS5 A;  5JVZ A;  4ZH8 B;  2FZZ L;  1M1X B;  3KQD L;  1NFW B;  2WPL E;  2DDU A;  4CUE A;  3KQB L;  3QMO A;  1HRF A;  1SZB A;  4BXW A;  1HAF A;  3KRK A;  3LC3 B;  2WFX B;  2J34 B;  3ZYI B;  1HCG B;  3IIT B;  2MHP A;  4Y7A B;  2KV4 A;  3LTF B;  5F19 A;  5JVY A;  3N8Z A;  4BDX A;  3N8W B;  4JZF L;  1L5G B;  1G1Q A;  2EI7 B;  2XBV L;  3LAQ A;  4ISI L;  3MDL A;  2B7D L;  3C9A C;  1NZI A;  1XKA L;  3M37 L;  5CKM A;  1APO A;  2W2N E;  2OYE P;  2Q1J B;  4X8V L;  1HX2 A;  2Y5F L;  2P3U A;  2W26 B;  2VVC K;  1FFM A;  1V3X B;  4O02 B;  4RRX A;  2WYJ B;  1EQH A;  2P95 L;  3KQE L;  4Y76 B;  1P9J A;  2P16 L;  5COX A;  2F9B L;  4X8S L;  4YT6 L;  1JV2 B;  2VWM K;  2Y81 B;  1J9C L;  2Y7X B;  4XBM A;  1HT5 A;  2Y7Z B;  1HT8 A;  1EAI C;  2J38 B;  3TK6 B;  3EGF A;  2AYL A;  1ATA A;  4TGF A;  1N1I A;  1U67 A;  1CEJ A;  2Y80 B;  3N8Y A;  1FSB A;  1ATD A;  1NFX B;  1IQJ L;  1URK A;  1G1S A;  4JZE L;  1W7X L;  2OYU P;  3CA7 A;  4MMZ B;  1FF7 A;  1DIY A;  1DVA L;  1QFK L;  1IQG L;  3LC5 B;  1YUF A;  2J2U B;  2BMG A;  1ZAQ A;  3RR3 A;  2Y82 B;  2ADX A;  1IQF L;  4ZAE B;  3ZYJ B;  4O1Z A;  2W2P E;  4Z6A L;  3N8V A;  1DX5 I;  3BT1 A;  4CUD A;  1Q4G A;  2WPI E;  3IJE B;  1NPE B;  1K37 A;  1MQ5 L;  2BOX A;  1ATE A;  4PH9 A;  1EZQ B;  1JBU L;  3H5C B;  4XLW A;  4CUF A;  3SOV A;  5IKQ A;  1GK5 A;  3QH0 A;  1F0R B;  2Y5G L;  3U7U G;  2J94 B;  3LTG D;  1FAK L;  5JBC E;  2VVV L;  1G1T A;  2UWP B;  2P28 B;  4Y6D B;  2TGF A;  4BTT A;  4X8T L;  1XFE A;  2RA0 L;  5JB8 E;  1CX2 A;  2FLR L;  5I46 L;  1CVU A;  1KSN B;  1G2M B;  1IGZ A;  4NGA L;  3ELA L;  1K36 A;  3CS7 L;  3SOB B;  1CQE A;  1X7A L;  4COX A;  1DQB A;  4JYU L;  4BDW A;  4BTI A;  2P26 A;  2WFT A;  5L2Z L;  1IQI L;  4RS0 A;  3LIW B;  1IQH L;  1PGE A;  2MGP A;  3GIS X;  2WYG B;  4D0E A;  1PRH A;  1IQM L;  2VVU L;  3CEN L;  1YUG A;  4Z0L A;  2VWO L;  3ENS A;  1COU A;  3NTB A;  1MOX C;  5JBB E;  4D0F A;  3KQC L;  1WU1 B;  2M74 A;  1IOX A;  1Z6E L;  2EI6 B;  2UWO B;  1IQK L;  4LMF A;  2JKH L;  1IQL L;  3LN1 A;  3F6U L;  3FBY A;  1IGX A;  2XC4 L;  5JW1 A;  2K2S B; 
#chains in the Genus database with same CATH topology
 4ZXY L;  2G00 L;  1UZP A;  3S6X A;  1LK9 A;  3TZI A;  2BQW A;  5CKN A;  2KB9 A;  2W86 A;  4BTU A;  1HJ7 A;  2FD6 A;  1HAE A;  4OTY A;  3TGF A;  5CIS A;  2KL7 A;  2YGO A;  3NTG A;  2WPK E;  1EPJ A;  3FCS B;  3KL6 B;  3M36 L;  1L3Y A;  3P5B L;  3V65 B;  2W2M E;  2PR3 B;  1NFY B;  3V64 C;  4Y7B B;  2BT7 A;  4NA9 L;  1QIU A;  3FFG L;  3SW2 A;  3PGH A;  4X8U L;  1PFX L;  1KLI L;  3GCX E;  4OTJ A;  2VH0 B;  2Y5H L;  1EPG A;  1FE2 A;  1IJQ A;  5JB9 E;  1CCF A;  1EBV A;  1WHE A;  3HO3 A;  1BF9 A;  2BZ6 L;  3HS7 A;  4RUT A;  1EMN A;  1Z6C A;  1DDX A;  2Y38 A;  4AQT A;  1FJS L;  3U73 A;  3KCG L;  2YGP A;  1UZK A;  5L2Y L;  3N8W A;  1CCV A;  3F1S B;  2J95 B;  1U8C B;  6COX A;  2KNI A;  3SOQ A;  1HRE A;  4Y71 B;  2BOU A;  1I0U A;  4XL1 A;  3TK5 B;  1EMO A;  4JYV L;  3NT1 A;  1PXX A;  4E1G A;  2I9A A;  5IKT A;  1ADX A;  1KKE A;  2BQ6 A;  3Q7D A;  4BXS A;  2BOH A;  1XDT R;  3R05 A;  3HPT A;  1C5M F;  1YGC L;  5E8D A;  2W3I B;  4MMX B;  2P3F N;  3QCW A;  2VJ3 A;  4ISH L;  1APQ A;  1EGF A;  3N8Y B;  1LQD A;  3MQE A;  2P93 L;  1LMJ A;  3ASI A;  3TH3 L;  1EQG A;  2BOK L;  2WG4 B;  1CVW L;  2H9E C;  1G1R A;  4M11 A;  4D90 A;  4YZU B;  1NFU B;  5KIR A;  2HOR A;  4ZHA B;  2UWL B;  2FLB L;  1KLO A;  2XBW L;  3POY A;  5JBA E;  4LOR A;  1OB1 C;  2BQ7 A;  3OLU A;  2VH6 B;  4MMY B;  1XKB A;  2WZP P;  3GCW E;  1NQL B;  2MGR A;  2P94 L;  2WPJ E;  4A7I A;  3LN0 A;  1O5D L;  4Y79 B;  5CKQ A;  3BT2 A;  1F7E A;  3N8X A;  4RRY A;  4ZXX L;  1TPG A;  2XBX L;  3Q3K B;  4G1M B;  1RFN B;  1N7D A;  1G2L B;  4Z0K B;  5KN5 C;  1EPI A;  1TLE A;  1YUK B;  2PHB B;  3HO4 A;  4NG9 L;  1TOZ A;  1IQE L;  4CSY A;  2CJI B;  4M10 A;  3HO5 A;  2P3F L;  5FDQ A;  4YT7 L;  1LPZ A;  2XC5 L;  4RRW A;  2W3K B;  2BO2 A;  4GU3 A;  4JZD L;  4C16 A;  1F7M A;  5IKR A;  1AUT L;  1P0S L;  1FAX L;  2XC0 L;  2WPM E;  3OLT A;  1EPH A;  3BPS E;  2P3T A;  1IQN L;  5L30 L;  1B9W A;  2EI8 B;  1JL9 A;  1HZ8 A;  1W8B L;  2PUQ L;  1KIG L;  2GD4 A;  2H9E L;  1F0S B;  2JJL A;  2WPH E;  2J4I B;  4RRZ A;  1LPG A;  2RNL A;  3HS6 A;  1IP0 A;  1ATB A;  1MQ6 L;  5K0H B;  1IOE L;  2D1J B;  2K2T A;  1KLJ L;  1LPK A;  2XBY L;  1LMM A;  5IKV A;  1IVO C;  1NT0 A;  2VWN L;  1UZJ A;  2NPR A;  3DEM A;  1YO8 A;  2W2Q E;  5EGM B;  1UZQ A;  3K9X A;  2RHP A;  3TBD A;  3CFW A;  1A3P A;  4FM5 A;  3ZYG A;  3NJP C;  1PTH A;  1WHF A;  2W2O E;  2VWL L;  2WG3 C;  2I9B A;  5F1A A;  3KK6 A;  2FLG A;  3HS5 A;  5JVZ A;  4ZH8 B;  2FZZ L;  1M1X B;  3KQD L;  1NFW B;  2WPL E;  2DDU A;  4CUE A;  3KQB L;  3QMO A;  1HRF A;  1SZB A;  4BXW A;  1HAF A;  3KRK A;  3LC3 B;  2WFX B;  2J34 B;  3ZYI B;  4A94 C;  1HCG B;  3IIT B;  2BSF A;  2MHP A;  4Y7A B;  2KV4 A;  3LTF B;  5F19 A;  5JVY A;  3N8Z A;  4BDX A;  3N8W B;  4JZF L;  1L5G B;  1G1Q A;  2EI7 B;  2XBV L;  3LAQ A;  4ISI L;  3MDL A;  2B7D L;  3C9A C;  1NZI A;  1XKA L;  3M37 L;  5CKM A;  1APO A;  2W2N E;  2OYE P;  2Q1J B;  4X8V L;  1HX2 A;  2Y5F L;  2P3U A;  2W26 B;  2YGQ A;  2VVC K;  1FFM A;  1V3X B;  4O02 B;  4RRX A;  2WYJ B;  1EQH A;  2P95 L;  3KQE L;  4Y76 B;  1P9J A;  2P16 L;  5COX A;  2F9B L;  4X8S L;  4YT6 L;  4GU4 A;  1JV2 B;  2VWM K;  2Y81 B;  1J9C L;  2Y7X B;  4XBM A;  1V1H A;  1HT5 A;  2Y7Z B;  1HT8 A;  1EAI C;  2J38 B;  3TK6 B;  3EGF A;  2AYL A;  1ATA A;  4TGF A;  1N1I A;  1U67 A;  1CEJ A;  2Y80 B;  3N8Y A;  1FSB A;  1ATD A;  1NFX B;  1IQJ L;  1URK A;  2HOX A;  1G1S A;  4JZE L;  1W7X L;  2OYU P;  3CA7 A;  4MMZ B;  1FF7 A;  1DIY A;  1DVA L;  2VRS A;  1QFK L;  1IQG L;  3LC5 B;  1YUF A;  2J2U B;  2BMG A;  1ZAQ A;  3RR3 A;  2Y82 B;  2ADX A;  1IQF L;  4ZAE B;  3ZYJ B;  4O1Z A;  2W2P E;  4Z6A L;  3N8V A;  1DX5 I;  3BT1 A;  4CUD A;  1Q4G A;  2WPI E;  3IJE B;  1NPE B;  1K37 A;  1MQ5 L;  2BOX A;  1ATE A;  4PH9 A;  1EZQ B;  1JBU L;  3H5C B;  4XLW A;  4CUF A;  3SOV A;  5IKQ A;  1GK5 A;  3QH0 A;  1F0R B;  2Y5G L;  3U7U G;  2J94 B;  3LTG D;  1FAK L;  5JBC E;  2VVV L;  1G1T A;  2UWP B;  2P28 B;  4Y6D B;  2TGF A;  4BTT A;  4X8T L;  1XFE A;  2RA0 L;  5JB8 E;  1CX2 A;  2FLR L;  5I46 L;  1CVU A;  1KSN B;  1G2M B;  1IGZ A;  4NGA L;  3ELA L;  1K36 A;  3CS7 L;  3SOB B;  1CQE A;  1X7A L;  4COX A;  1DQB A;  4JYU L;  4BDW A;  4BTI A;  2P26 A;  2WFT A;  5L2Z L;  1IQI L;  4RS0 A;  3LIW B;  1IQH L;  1PGE A;  2MGP A;  3GIS X;  2WYG B;  4D0E A;  1PRH A;  1IQM L;  2BT8 A;  2VVU L;  3CEN L;  1YUG A;  4Z0L A;  2VWO L;  3ENS A;  1V1I A;  1COU A;  3NTB A;  1MOX C;  5JBB E;  4D0F A;  3KQC L;  1WU1 B;  2M74 A;  1IOX A;  1Z6E L;  2EI6 B;  2UWO B;  1IQK L;  4LMF A;  2JKH L;  1IQL L;  3LN1 A;  3F6U L;  3FBY A;  1IGX A;  2XC4 L;  5JW1 A;  2K2S B; 
#chains in the Genus database with same CATH homology
 4ZXY L;  2G00 L;  1UZP A;  3S6X A;  3TZI A;  2BQW A;  5CKN A;  2KB9 A;  2W86 A;  4BTU A;  1HJ7 A;  2FD6 A;  1HAE A;  4OTY A;  3TGF A;  5CIS A;  2KL7 A;  2YGO A;  3NTG A;  2WPK E;  1EPJ A;  3FCS B;  3KL6 B;  3M36 L;  1L3Y A;  3P5B L;  3V65 B;  2W2M E;  2PR3 B;  1NFY B;  3V64 C;  4Y7B B;  4NA9 L;  3FFG L;  3SW2 A;  3PGH A;  4X8U L;  1PFX L;  1KLI L;  3GCX E;  4OTJ A;  2VH0 B;  2Y5H L;  1EPG A;  1FE2 A;  1IJQ A;  5JB9 E;  1CCF A;  1EBV A;  1WHE A;  3HO3 A;  1BF9 A;  2BZ6 L;  3HS7 A;  4RUT A;  1EMN A;  1Z6C A;  1DDX A;  2Y38 A;  4AQT A;  1FJS L;  3U73 A;  3KCG L;  2YGP A;  1UZK A;  5L2Y L;  3N8W A;  1CCV A;  3F1S B;  2J95 B;  1U8C B;  6COX A;  2KNI A;  3SOQ A;  1HRE A;  4Y71 B;  2BOU A;  1I0U A;  4XL1 A;  3TK5 B;  1EMO A;  4JYV L;  3NT1 A;  1PXX A;  4E1G A;  2I9A A;  5IKT A;  1ADX A;  2BQ6 A;  3Q7D A;  4BXS A;  2BOH A;  1XDT R;  3R05 A;  3HPT A;  1C5M F;  1YGC L;  5E8D A;  2W3I B;  4MMX B;  2P3F N;  3QCW A;  2VJ3 A;  4ISH L;  1APQ A;  1EGF A;  3N8Y B;  1LQD A;  3MQE A;  2P93 L;  1LMJ A;  3ASI A;  3TH3 L;  1EQG A;  2BOK L;  2WG4 B;  1CVW L;  2H9E C;  1G1R A;  4M11 A;  4D90 A;  4YZU B;  1NFU B;  5KIR A;  4ZHA B;  2UWL B;  2FLB L;  1KLO A;  2XBW L;  3POY A;  5JBA E;  4LOR A;  1OB1 C;  2BQ7 A;  3OLU A;  2VH6 B;  4MMY B;  1XKB A;  2WZP P;  3GCW E;  1NQL B;  2MGR A;  2P94 L;  2WPJ E;  4A7I A;  3LN0 A;  1O5D L;  4Y79 B;  5CKQ A;  3BT2 A;  1F7E A;  3N8X A;  4RRY A;  4ZXX L;  1TPG A;  2XBX L;  3Q3K B;  4G1M B;  1RFN B;  1N7D A;  1G2L B;  4Z0K B;  5KN5 C;  1EPI A;  1TLE A;  1YUK B;  2PHB B;  3HO4 A;  4NG9 L;  1TOZ A;  1IQE L;  4CSY A;  2CJI B;  4M10 A;  3HO5 A;  2P3F L;  5FDQ A;  4YT7 L;  1LPZ A;  2XC5 L;  4RRW A;  2W3K B;  2BO2 A;  4JZD L;  4C16 A;  1F7M A;  5IKR A;  1AUT L;  1P0S L;  1FAX L;  2XC0 L;  2WPM E;  3OLT A;  1EPH A;  3BPS E;  2P3T A;  1IQN L;  5L30 L;  1B9W A;  2EI8 B;  1JL9 A;  1HZ8 A;  1W8B L;  2PUQ L;  1KIG L;  2GD4 A;  2H9E L;  1F0S B;  2WPH E;  2J4I B;  4RRZ A;  1LPG A;  2RNL A;  3HS6 A;  1IP0 A;  1ATB A;  1MQ6 L;  5K0H B;  1IOE L;  2D1J B;  2K2T A;  1KLJ L;  1LPK A;  2XBY L;  1LMM A;  5IKV A;  1IVO C;  1NT0 A;  2VWN L;  1UZJ A;  2NPR A;  3DEM A;  1YO8 A;  2W2Q E;  5EGM B;  1UZQ A;  3K9X A;  2RHP A;  3TBD A;  3CFW A;  1A3P A;  4FM5 A;  3ZYG A;  3NJP C;  1PTH A;  1WHF A;  2W2O E;  2VWL L;  2WG3 C;  2I9B A;  5F1A A;  3KK6 A;  2FLG A;  3HS5 A;  5JVZ A;  4ZH8 B;  2FZZ L;  1M1X B;  3KQD L;  1NFW B;  2WPL E;  2DDU A;  4CUE A;  3KQB L;  3QMO A;  1HRF A;  1SZB A;  4BXW A;  1HAF A;  3KRK A;  3LC3 B;  2WFX B;  2J34 B;  3ZYI B;  4A94 C;  1HCG B;  3IIT B;  2MHP A;  4Y7A B;  2KV4 A;  3LTF B;  5F19 A;  5JVY A;  3N8Z A;  4BDX A;  3N8W B;  4JZF L;  1L5G B;  1G1Q A;  2EI7 B;  2XBV L;  3LAQ A;  4ISI L;  3MDL A;  2B7D L;  3C9A C;  1NZI A;  1XKA L;  3M37 L;  5CKM A;  1APO A;  2W2N E;  2OYE P;  2Q1J B;  4X8V L;  1HX2 A;  2Y5F L;  2P3U A;  2W26 B;  2YGQ A;  2VVC K;  1FFM A;  1V3X B;  4O02 B;  4RRX A;  2WYJ B;  1EQH A;  2P95 L;  3KQE L;  4Y76 B;  1P9J A;  2P16 L;  5COX A;  2F9B L;  4X8S L;  4YT6 L;  1JV2 B;  2VWM K;  2Y81 B;  1J9C L;  2Y7X B;  4XBM A;  1HT5 A;  2Y7Z B;  1HT8 A;  1EAI C;  2J38 B;  3TK6 B;  3EGF A;  2AYL A;  1ATA A;  4TGF A;  1N1I A;  1U67 A;  1CEJ A;  2Y80 B;  3N8Y A;  1FSB A;  1ATD A;  1NFX B;  1IQJ L;  1URK A;  1G1S A;  4JZE L;  1W7X L;  2OYU P;  3CA7 A;  4MMZ B;  1FF7 A;  1DIY A;  1DVA L;  1QFK L;  1IQG L;  3LC5 B;  1YUF A;  2J2U B;  2BMG A;  1ZAQ A;  3RR3 A;  2Y82 B;  2ADX A;  1IQF L;  4ZAE B;  3ZYJ B;  4O1Z A;  2W2P E;  4Z6A L;  3N8V A;  1DX5 I;  3BT1 A;  4CUD A;  1Q4G A;  2WPI E;  3IJE B;  1NPE B;  1K37 A;  1MQ5 L;  2BOX A;  1ATE A;  4PH9 A;  1EZQ B;  1JBU L;  3H5C B;  4XLW A;  4CUF A;  3SOV A;  5IKQ A;  1GK5 A;  3QH0 A;  1F0R B;  2Y5G L;  3U7U G;  2J94 B;  3LTG D;  1FAK L;  5JBC E;  2VVV L;  1G1T A;  2UWP B;  2P28 B;  4Y6D B;  2TGF A;  4BTT A;  4X8T L;  1XFE A;  2RA0 L;  5JB8 E;  1CX2 A;  2FLR L;  5I46 L;  1CVU A;  1KSN B;  1G2M B;  1IGZ A;  4NGA L;  3ELA L;  1K36 A;  3CS7 L;  3SOB B;  1CQE A;  1X7A L;  4COX A;  1DQB A;  4JYU L;  4BDW A;  4BTI A;  2P26 A;  2WFT A;  5L2Z L;  1IQI L;  4RS0 A;  3LIW B;  1IQH L;  1PGE A;  2MGP A;  3GIS X;  2WYG B;  4D0E A;  1PRH A;  1IQM L;  2VVU L;  3CEN L;  1YUG A;  4Z0L A;  2VWO L;  3ENS A;  1COU A;  3NTB A;  1MOX C;  5JBB E;  4D0F A;  3KQC L;  1WU1 B;  2M74 A;  1IOX A;  1Z6E L;  2EI6 B;  2UWO B;  1IQK L;  4LMF A;  2JKH L;  1IQL L;  3LN1 A;  3F6U L;  3FBY A;  1IGX A;  2XC4 L;  5JW1 A;  2K2S B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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