2YGSA

Card domain from apaf-1
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
92
structure length
92
Chain Sequence
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Apoptosis
molecule keywords APOPTOTIC PROTEASE ACTIVATING FACTOR 1
total genus 32
structure length 92
sequence length 92
ec nomenclature
pdb deposition date 1999-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2ygsA00
2BBRA 3LQQA 1C15A 1PN5A 4ZBWA 4M9XA 2L9MA 4IZ5E 2DBDA 1A1ZA 2DBGA 2NSNA 4RHWE 4DWNA 2F1SA 2N00A 2GF5A 4JUPA 2MS7A 2YQFA 2BBZA 4N1KA 4IZAB 4LWDA 4M9ZA 4M9SA 1N3KA 2KM6A 3EZQA 2O71A 3QF2A 4O7QA 3KATA 4P4HA 4F44A 2A9IA 3MOPA 3LQRA 2N80A 4O9FA 2DO9A 2G7RA 1UCPA 2N97A 2MPCA 1ICHA 2B1WA 1WMGA 1D2ZA 1Z6TA 2IB1A 2YU0A 4O9LA 2VGQA 4A2WA 2HM2Q 2MS8A 2L6AA 2D96A 2NAQA 4IZ7B 1FADA 3YGSC 2M5VA 3CL3A 2NZ7A 1DDFA 3MOPG 4F42A 2OF5A 3T6PA 1WXPA 2P1HA 3J63A 4RHWA 2YVIA 4E9MA 4N1JA 3YGSP 1D2ZB 4P4HI 1E3YA 3CRDA 2N83A 4FH0A 2LWDA 4I16A 4NQKA 4D8OA 2LWEA 4QOBA 4O6XA 1WH4A 2LS7A 4A2QA 2OF5H 3J6JA 2A5YB 1DGNA 1YGOA 1A1WA 1E41A 2DBFA 4UZ0A 2N7ZA 3MOPK 2MB9A 1CY5A 1CWWA 4JQWA 2YGSA 2N1FA 2KN6A 2MN4A 3EZQB 4EWIA 4N1LA 2DBHA 1NGRA
chains in the Genus database with same CATH superfamily
2BBRA 3LQQA 1C15A 1PN5A 4ZBWA 4M9XA 2L9MA 4IZ5E 2DBDA 1A1ZA 2DBGA 2NSNA 4RHWE 4DWNA 2F1SA 2N00A 2GF5A 4JUPA 2MS7A 2YQFA 2BBZA 4N1KA 4IZAB 4LWDA 4M9ZA 4M9SA 1N3KA 2KM6A 3EZQA 2O71A 3QF2A 2MJMA 4O7QA 3KATA 4P4HA 4F44A 2A9IA 3MOPA 3LQRA 2N80A 4O9FA 2DO9A 2G7RA 1UCPA 2XV9A 2N97A 2MPCA 1ICHA 2B1WA 1WMGA 1D2ZA 1Z6TA 2IB1A 2YU0A 4O9LA 2VGQA 4A2WA 2HM2Q 2MS8A 2L6AA 2D96A 2NAQA 4IZ7B 1FADA 3YGSC 2M5VA 3CL3A 2NZ7A 1DDFA 3MOPG 4F42A 2OF5A 3T6PA 1WXPA 2P1HA 3J63A 4RHWA 2YVIA 4E9MA 4N1JA 3YGSP 1D2ZB 4P4HI 1E3YA 3CRDA 2N83A 4FH0A 2LWDA 4I16A 4NQKA 4D8OA 2LWEA 4QOBA 4O6XA 1WH4A 2LS7A 4A2QA 2OF5H 3J6JA 2A5YB 1DGNA 1YGOA 1A1WA 1E41A 2DBFA 4UZ0A 2N7ZA 3MOPK 2MB9A 1CY5A 1CWWA 4JQWA 2YGSA 2N1FA 2KN6A 2MN4A 3EZQB 4EWIA 4N1LA 2DBHA 1NGRA
chains in the Genus database with same CATH topology
2BBRA 3LQQA 1C15A 1PN5A 4ZBWA 4M9XA 2L9MA 4IZ5E 2DBDA 1A1ZA 2DBGA 2NSNA 4RHWE 4DWNA 2F1SA 2N00A 2GF5A 4JUPA 2MS7A 2YQFA 2BBZA 4N1KA 4IZAB 4LWDA 4M9ZA 4M9SA 1N3KA 2KM6A 3EZQA 2O71A 3QF2A 2MJMA 4O7QA 3KATA 4P4HA 4F44A 2A9IA 3MOPA 3LQRA 2N80A 4O9FA 2DO9A 2G7RA 1UCPA 2XV9A 2N97A 2MPCA 1ICHA 2B1WA 1WMGA 1D2ZA 1Z6TA 2IB1A 2YU0A 4O9LA 2VGQA 4A2WA 2HM2Q 2MS8A 2L6AA 2D96A 2NAQA 4IZ7B 1FADA 3YGSC 2M5VA 3CL3A 2NZ7A 1DDFA 3MOPG 4F42A 2OF5A 3T6PA 1WXPA 2P1HA 3J63A 4RHWA 2YVIA 4E9MA 4N1JA 3YGSP 1D2ZB 4P4HI 1E3YA 3CRDA 2N83A 4FH0A 2LWDA 4I16A 4NQKA 4D8OA 2LWEA 4QOBA 4O6XA 1WH4A 2LS7A 4A2QA 2OF5H 3J6JA 2A5YB 1DGNA 1YGOA 1A1WA 1E41A 2DBFA 4UZ0A 2N7ZA 3MOPK 2MB9A 1CY5A 1CWWA 4JQWA 2YGSA 2N1FA 2KN6A 2MN4A 3EZQB 4EWIA 4N1LA 2DBHA 1NGRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BBR A;  3LQQ A;  1C15 A;  1PN5 A;  4ZBW A;  4M9X A;  2L9M A;  4IZ5 E;  2DBD A;  1A1Z A;  2DBG A;  2NSN A;  4RHW E;  4DWN A;  2F1S A;  2N00 A;  2GF5 A;  4JUP A;  2MS7 A;  2YQF A;  2BBZ A;  4N1K A;  4IZA B;  4LWD A;  4M9Z A;  4M9S A;  1N3K A;  2KM6 A;  3EZQ A;  2O71 A;  3QF2 A;  4O7Q A;  3KAT A;  4P4H A;  4F44 A;  2A9I A;  3MOP A;  3LQR A;  2N80 A;  4O9F A;  2DO9 A;  2G7R A;  1UCP A;  2N97 A;  2MPC A;  1ICH A;  2B1W A;  1WMG A;  1D2Z A;  1Z6T A;  2IB1 A;  2YU0 A;  4O9L A;  2VGQ A;  4A2W A;  2HM2 Q;  2MS8 A;  2L6A A;  2D96 A;  2NAQ A;  4IZ7 B;  1FAD A;  3YGS C;  2M5V A;  3CL3 A;  2NZ7 A;  1DDF A;  3MOP G;  4F42 A;  2OF5 A;  3T6P A;  1WXP A;  2P1H A;  3J63 A;  4RHW A;  2YVI A;  4E9M A;  4N1J A;  3YGS P;  1D2Z B;  4P4H I;  1E3Y A;  3CRD A;  2N83 A;  4FH0 A;  2LWD A;  4I16 A;  4NQK A;  4D8O A;  2LWE A;  4QOB A;  4O6X A;  1WH4 A;  2LS7 A;  4A2Q A;  2OF5 H;  3J6J A;  2A5Y B;  1DGN A;  1YGO A;  1A1W A;  1E41 A;  2DBF A;  4UZ0 A;  2N7Z A;  3MOP K;  2MB9 A;  1CY5 A;  1CWW A;  4JQW A;  2YGS A;  2N1F A;  2KN6 A;  2MN4 A;  3EZQ B;  4EWI A;  4N1L A;  2DBH A;  1NGR A; 
#chains in the Genus database with same CATH topology
 2BBR A;  3LQQ A;  1C15 A;  1PN5 A;  4ZBW A;  4M9X A;  2L9M A;  4IZ5 E;  2DBD A;  1A1Z A;  2DBG A;  2NSN A;  4RHW E;  4DWN A;  2F1S A;  2N00 A;  2GF5 A;  4JUP A;  2MS7 A;  2YQF A;  2BBZ A;  4N1K A;  4IZA B;  4LWD A;  4M9Z A;  4M9S A;  1N3K A;  2KM6 A;  3EZQ A;  2O71 A;  3QF2 A;  2MJM A;  4O7Q A;  3KAT A;  4P4H A;  4F44 A;  2A9I A;  3MOP A;  3LQR A;  2N80 A;  4O9F A;  2DO9 A;  2G7R A;  1UCP A;  2XV9 A;  2N97 A;  2MPC A;  1ICH A;  2B1W A;  1WMG A;  1D2Z A;  1Z6T A;  2IB1 A;  2YU0 A;  4O9L A;  2VGQ A;  4A2W A;  2HM2 Q;  2MS8 A;  2L6A A;  2D96 A;  2NAQ A;  4IZ7 B;  1FAD A;  3YGS C;  2M5V A;  3CL3 A;  2NZ7 A;  1DDF A;  3MOP G;  4F42 A;  2OF5 A;  3T6P A;  1WXP A;  2P1H A;  3J63 A;  4RHW A;  2YVI A;  4E9M A;  4N1J A;  3YGS P;  1D2Z B;  4P4H I;  1E3Y A;  3CRD A;  2N83 A;  4FH0 A;  2LWD A;  4I16 A;  4NQK A;  4D8O A;  2LWE A;  4QOB A;  4O6X A;  1WH4 A;  2LS7 A;  4A2Q A;  2OF5 H;  3J6J A;  2A5Y B;  1DGN A;  1YGO A;  1A1W A;  1E41 A;  2DBF A;  4UZ0 A;  2N7Z A;  3MOP K;  2MB9 A;  1CY5 A;  1CWW A;  4JQW A;  2YGS A;  2N1F A;  2KN6 A;  2MN4 A;  3EZQ B;  4EWI A;  4N1L A;  2DBH A;  1NGR A; 
#chains in the Genus database with same CATH homology
 2BBR A;  3LQQ A;  1C15 A;  1PN5 A;  4ZBW A;  4M9X A;  2L9M A;  4IZ5 E;  2DBD A;  1A1Z A;  2DBG A;  2NSN A;  4RHW E;  4DWN A;  2F1S A;  2N00 A;  2GF5 A;  4JUP A;  2MS7 A;  2YQF A;  2BBZ A;  4N1K A;  4IZA B;  4LWD A;  4M9Z A;  4M9S A;  1N3K A;  2KM6 A;  3EZQ A;  2O71 A;  3QF2 A;  2MJM A;  4O7Q A;  3KAT A;  4P4H A;  4F44 A;  2A9I A;  3MOP A;  3LQR A;  2N80 A;  4O9F A;  2DO9 A;  2G7R A;  1UCP A;  2XV9 A;  2N97 A;  2MPC A;  1ICH A;  2B1W A;  1WMG A;  1D2Z A;  1Z6T A;  2IB1 A;  2YU0 A;  4O9L A;  2VGQ A;  4A2W A;  2HM2 Q;  2MS8 A;  2L6A A;  2D96 A;  2NAQ A;  4IZ7 B;  1FAD A;  3YGS C;  2M5V A;  3CL3 A;  2NZ7 A;  1DDF A;  3MOP G;  4F42 A;  2OF5 A;  3T6P A;  1WXP A;  2P1H A;  3J63 A;  4RHW A;  2YVI A;  4E9M A;  4N1J A;  3YGS P;  1D2Z B;  4P4H I;  1E3Y A;  3CRD A;  2N83 A;  4FH0 A;  2LWD A;  4I16 A;  4NQK A;  4D8O A;  2LWE A;  4QOB A;  4O6X A;  1WH4 A;  2LS7 A;  4A2Q A;  2OF5 H;  3J6J A;  2A5Y B;  1DGN A;  1YGO A;  1A1W A;  1E41 A;  2DBF A;  4UZ0 A;  2N7Z A;  3MOP K;  2MB9 A;  1CY5 A;  1CWW A;  4JQW A;  2YGS A;  2N1F A;  2KN6 A;  2MN4 A;  3EZQ B;  4EWI A;  4N1L A;  2DBH A;  1NGR A; 
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similar chains in the pdb database (?% sequence similarity)

 
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