2YPBA

Structure of the scl:e47 complex bound to dna
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
67
structure length
67
Chain Sequence
GPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1
publication title Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
pubmed doi rcsb
source organism Homo sapiens
total genus 25
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 2012-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 2ypbA00
1AN2A 2MH3A 1UKLC 4F3LA 2QL2A 4ATHA 5I50A 1A0AA 4AYAA 1MDYB 4ATKA 1R05A 1HLOA 2YPAB 1NKPB 4H10B 1NLWB 1MDYA 3MUJA 2YPAA 5EYOA 2YPBB 4ATIA 1NKPA 3U5VA 4H10A 5I4ZA 1AN4A 2LFHA 1AM9A 4F3LB 1NLWA 2YPBA 2QL2B
chains in the Genus database with same CATH superfamily
1AN2A 2MH3A 1UKLC 4F3LA 2QL2A 4ATHA 5I50A 1K1FA 1A0AA 4AYAA 1MDYB 4ATKA 1R05A 1HLOA 2YPAB 1NKPB 4H10B 1NLWB 1MDYA 3MUJA 2YPAA 5EYOA 2YPBB 4ATIA 1NKPA 3U5VA 1ZZAA 4H10A 5I4ZA 1AN4A 2LFHA 1AM9A 4F3LB 1NLWA 2YPBA 2QL2B
chains in the Genus database with same CATH topology
1AN2A 2MH3A 1UKLC 4F3LA 2QL2A 4ATHA 5I50A 1A0AA 4AYAA 1MDYB 4ATKA 1R05A 1HLOA 2YPAB 1NKPB 4H10B 1NLWB 1MDYA 3MUJA 2YPAA 5EYOA 2YPBB 4ATIA 1NKPA 3U5VA 4H10A 5I4ZA 1AN4A 2LFHA 1AM9A 4F3LB 1NLWA 2YPBA 2QL2B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AN2 A;  2MH3 A;  1UKL C;  4F3L A;  2QL2 A;  4ATH A;  5I50 A;  1A0A A;  4AYA A;  1MDY B;  4ATK A;  1R05 A;  1HLO A;  2YPA B;  1NKP B;  4H10 B;  1NLW B;  1MDY A;  3MUJ A;  2YPA A;  5EYO A;  2YPB B;  4ATI A;  1NKP A;  3U5V A;  4H10 A;  5I4Z A;  1AN4 A;  2LFH A;  1AM9 A;  4F3L B;  1NLW A;  2YPB A;  2QL2 B; 
#chains in the Genus database with same CATH topology
 1AN2 A;  2MH3 A;  1UKL C;  4F3L A;  2QL2 A;  4ATH A;  5I50 A;  1K1F A;  1A0A A;  4AYA A;  1MDY B;  4ATK A;  1R05 A;  1HLO A;  2YPA B;  1NKP B;  4H10 B;  1NLW B;  1MDY A;  3MUJ A;  2YPA A;  5EYO A;  2YPB B;  4ATI A;  1NKP A;  3U5V A;  1ZZA A;  4H10 A;  5I4Z A;  1AN4 A;  2LFH A;  1AM9 A;  4F3L B;  1NLW A;  2YPB A;  2QL2 B; 
#chains in the Genus database with same CATH homology
 1AN2 A;  2MH3 A;  1UKL C;  4F3L A;  2QL2 A;  4ATH A;  5I50 A;  1A0A A;  4AYA A;  1MDY B;  4ATK A;  1R05 A;  1HLO A;  2YPA B;  1NKP B;  4H10 B;  1NLW B;  1MDY A;  3MUJ A;  2YPA A;  5EYO A;  2YPB B;  4ATI A;  1NKP A;  3U5V A;  4H10 A;  5I4Z A;  1AN4 A;  2LFH A;  1AM9 A;  4F3L B;  1NLW A;  2YPB A;  2QL2 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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