2Z0PA

Crystal structure of ph domain of bruton's tyrosine kinase
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
167
structure length
158
Chain Sequence
AAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQIL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the Bruton's tyrosine kinase PH domain with phosphatidylinositol
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Tyrosine-protein kinase BTK
total genus 34
structure length 158
sequence length 167
chains with identical sequence B, C, D
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2007-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF00779 BTK BTK motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2z0pA00
3ULBA 3SV1A 4K17A 5D27A 4Z2MB 1GG3A 1U5GA 5D3XA 2N0YA 2P0HA 3PVWA 4P7IA 1NTVA 1MIZB 5J3QA 5DH9B 1XODA 4IFSA 2L2IA 3A8QA 2G35A 1V5PA 4HAXB 1U5FA 3LJUX 1RJ2A 1DDWA 4YONA 1QC6A 2DN6A 1SHCA 1KZGA 2MFQA 2RUKB 2LOZA 2D9XA 1B55A 1Y19B 5KQ4A 1FGZA 5J3YA 2Z0OA 3X23A 2UZSA 4ZRIA 5JP4A 3F5RA 4F7HA 4IAPA 4KHAA 4GPTB 1LW3A 5J3TA 1UNPA 1XX0A 2YRYA 3HW2B 3KZ1A 3DXEA 1PLSA 3ODXA 1M7RA 4BBKA 1P3RA 1PFJA 3D8FA 2LYDA 1V61A 2P0FA 2DKQA 1XKEA 2DLWA 4H8SA 4WJ7A 1ZM0A 4A6FA 1U29A 1GC7A 2LOXA 1X05A 2EC1A 1P5TA 1QQGA 1FB8A 5DIFB 5CLQB 3T06A 2JP2A 3PZDA 5CLLB 1V89A 4D0NB 4YL8A 5LONB 2OQBA 1U27A 2LG1A 2D11A 3TO1A 1X1FA 1WGUA 2GJYA 2DHJA 3PP2A 1N3HA 2KCJA 1Q67A 2P8VA 4CYEA 1I7AA 4DXAB 2CODA 4HAVB 5JHGA 4B6HA 3SO6A 1MK9B 4A6FB 2NMBA 2K2JA 2DX5A 4HDOA 5DI9B 4WVFB 3TVVA 1DBHA 1IRSA 4TKNA 1FHWA 1V5UA 4XWXA 2UZRA 2RSGA 5C5BB 5GOWB 4HB0B 3SUZA 5D3YA 1MPHA 1UEFA 4PNKA 3KRWA 1GC6A 2YT0A 1U5DA 4HB2B 1SGHA 3D8EA 1FGYA 2H7DA 5L81A 1OQNA 5EFXA 5FI0A 1XD4A 4Y94A 3PSCA 1EAZA 2RNRB 2DFKA 1W1HA 4HHVA 4HB4B 4Z2NA 2R0DA 5KCVA 1NU2A 1X11A 4K81A 3PVUA 2DYQA 3DXCA 2HE7A 1P6SA 2GS0A 4GMVA 4A6KA 3FSSA 2LULA 2QKMA 2CRFA 3BINA 2R09A 3FEHA 4KHOA 1E5WA 1OY2A 1V88A 2Y8FA 5JLJB 3D8DA 5LOPB 1WGQA 1ZSQA 3HK0A 1XR0B 4A5KA 4MT7A 2I1JA 2I5CA 2YT1A 3P7ZA 3WA0A 4CHJA 1UNRA 2GCLA 5KQ1A 5HE3A 2K2UA 1WI1A 2Y8GA 2EMSA 3F0WA 4A6HA 1H4RA 1EGXA 1DDVA 3SNHA 3IVFA 2M14A 3FM8C 1LB1A 2DHKA 1DDMA 1TJ6A 1K5DB 1AWEA 3A98B 3KSYA 2K00A 1I2HA 1MKEA 5C5BA 3V5WA 1Z87A 4NSWA 4KHBB 4MY6A 2YS1A 5DHAB 4ZRJA 1U2BA 3KY9A 2XQNM 3TFMA 1ZVRA 3QWMA 3GYPA 4PQ0A 4HAYB 1X1GA 5C16A 1EVHA 1UPQA 3ZVRA 2HTHB 2COCA 2D9YA 2AL6A 1BTNA 3VIAA 3QIJA 1XCGA 4F7GA 2DA0A 2CY4A 1PMSA 2I1KA 2VKIA 4CHMA 1H10A 1EF1A 1W1DA 1Y5OA 1ZC4B 4EKUA 1KZ7A 1KI1B 1FHXA 4EMOA 2D9ZA 3AU4A 4K2PA 1MAIA 5JHHA 1WJMA 2BCJA 2OTXA 4C0AA 2COFA 3ODWA 2ELAA 2MWNB 2D2QA 3VOQA 4HAZB 1TXDA 5C79A 2W2XC 5C6RA 2MKRA 2D10A 2UVMA 2YS5A 3BJIA 3SYXA 4ZRKA 5D3WA 1FAOA 1UPRA 4TYZA 2ROZB 3TCAA 2ADZA 1FOEA 4GN1A 2QKLA 2J0MA 4L6EA 1V5MA 2J0KA 2DTCA 3AU5A 2IFSA 2MDXA 2M38A 1TQZA 2DYNA 2DX1A 4HAUB 4K2OA 5HE1A 3WYFB 1BTKA 2FJLA 2E2XA 2J59M 2D9VA 4GXBA 2H7EA 2LKOA 1WVHA 3DXDA 3P6AA 4HB3B 2RGNB 1BAKA 1MIXA 3ML4A 3QBVB 3KRXA 2D9WA 1FHOA 1W1GA 1K5GB 3RCPA 2CAYA 2X18A 3A8PA 1UNQA 4GZUA 1WJ1A 5D3VA 3PG7A 3GYOA 3MDBC 2I5FA 4DX8A 1NTYA 1OMWA 2COAA 4KVGB 2AEHA 2YVCA 3TW1A 3CIKA 3U7DA 2YSZA 4EJNA 1RRPB 1AQCA 1ZC3B 2EJ8A 2DHIA 2ROVA 2W2WA 4HAWB 2YS3A 4GMXB 1BWNA 3HQCA 3U8ZA 2RLOA 3MPXA 4IOYX 3M1IB 2ELBA 2N23A 2W2XD 1NI2A 2EMTA 3NSUA 2Q13A 3CXBB 5FI1A 2YF0A 1DYNA 2DKPA 2L1CA 3OANA 4DX90 1U5EA 1J19A 2KGXB 4DBBA 3ULCA 3G9WA 4HDQA 2GCJA 3PVLA 2VRWB 2V76A 4KAXB 3O96A 2Z0PA 3PEGA 2IYBA 2Y7BA 2KUPA 5HE0A 3N7CA 2P0DA 5DHFB 1MK7B 3ZDTA 1ISNA 2Z0QA 4NY0A 4MK0A 3AJ4A 2PZ1A 1J0WA 4F7UP 2RVBB 2VSZA 4WSFA 1M7EA 1X86A 1WG7A 3UZTA 1DROA 3ODOA 2D4QA 2CY5A 5HE2A 4HATB 2NZ8B 2ZPYA 2J0JA
chains in the Genus database with same CATH superfamily
3ULBA 3SV1A 4K17A 5D27A 4Z2MB 1GG3A 1U5GA 5D3XA 2N0YA 2P0HA 3PVWA 4P7IA 1NTVA 1MIZB 5J3QA 4GNKB 5DH9B 1XODA 4IFSA 2L2IA 3A8QA 2G35A 1V5PA 4HAXB 1U5FA 3LJUX 1RJ2A 1DDWA 4YONA 1QC6A 2DN6A 5I2SA 1SHCA 1KZGA 2MFQA 2RUKB 2LOZA 2D9XA 1B55A 1Y19B 5KQ4A 1FGZA 5I2MA 5J3YA 2Z0OA 3X23A 2UZSA 4ZRIA 5JP4A 3F5RA 4F7HA 2GUMA 4IAPA 4KHAA 4GPTB 1LW3A 5J3TA 1UNPA 1XX0A 2YRYA 2K49A 2YT2A 3HW2B 3KZ1A 3DXEA 1PLSA 3ODXA 1M7RA 4BBKA 1P3RA 1PFJA 3D8FA 2LYDA 1V61A 2P0FA 2DKQA 1XKEA 2DLWA 4H8SA 4WJ7A 1ZM0A 4A6FA 1U29A 1GC7A 2LOXA 1X05A 2EC1A 2Z4DA 1P5TA 1QQGA 1FB8A 5DIFB 5CLQB 3T06A 2JP2A 3PZDA 5CLLB 1V89A 4D0NB 4YL8A 5LONB 2OQBA 1U27A 2LG1A 2D11A 3TO1A 1X1FA 1WGUA 2GJYA 2DHJA 3PP2A 1N3HA 2KCJA 4CSQA 1Q67A 2P8VA 4CYEA 3NW8A 1I7AA 4DXAB 2CODA 4HAVB 5JHGA 4B6HA 3NWFA 3SO6A 1MK9B 4A6FB 2NMBA 2K2JA 2DX5A 4HDOA 5DI9B 4QXAB 4WVFB 3TVVA 1DBHA 1IRSA 4TKNA 1FHWA 1V5UA 4XWXA 4DIXA 2UZRA 2RSGA 5C5BB 5GOWB 4HB0B 2KIEA 3SUZA 5D3YA 2ZKMX 3HSAA 1MPHA 1UEFA 4PNKA 3KRWA 1GC6A 2YT0A 2KIGA 1U5DA 4HB2B 1SGHA 3D8EA 1FGYA 2H7DA 5L81A 1OQNA 5EFXA 5FI0A 4QJ5B 1XD4A 4Y94A 3PSCA 1EAZA 3B77A 2RNRB 2DFKA 1W1HA 4HHVA 4HB4B 4Z2NA 2R0DA 5KCVA 1NU2A 1X11A 4K81A 4OSNA 3PVUA 2DYQA 3DXCA 2HE7A 1P6SA 2RRFA 2GS0A 4GMVA 4A6KA 1MI1A 3FSSA 2LULA 2QKMA 4OT1A 2CRFA 3BINA 2R09A 3FEHA 4KHOA 1E5WA 1OY2A 1V88A 2Y8FA 5JLJB 3D8DA 5LOPB 1WGQA 1ZSQA 3HK0A 1XR0B 4A5KA 4KHBA 4MT7A 2I1JA 2I5CA 1ZYIA 2YT1A 3P7ZA 3WA0A 4CHJA 1UNRA 2GCLA 2FJUB 5KQ1A 2R2YA 5HE3A 2K2UA 1WI1A 2Y8GA 2EMSA 3F0WA 4A6HA 1H4RA 1EGXA 1DDVA 3SNHA 3IVFA 2M14A 3FM8C 1LB1A 2DHKA 1DDMA 1TJ6A 1K5DB 1AWEA 3A98B 3KSYA 2K00A 1I2HA 1MKEA 5C5BA 3V5WA 1Z87A 4NSWA 4KHBB 4MY6A 2YS1A 5DHAB 4ZRJA 1U2BA 3KY9A 2XQNM 3TFMA 1ZVRA 3QWMA 3GYPA 4PQ0A 3NWAA 4HAYB 1X1GA 5C16A 1EVHA 1UPQA 3ZVRA 2HTHB 2COCA 2D9YA 2AL6A 1BTNA 3VIAA 3QIJA 3OHMB 1XCGA 4F7GA 2DA0A 2CY4A 1PMSA 2I1KA 2VKIA 4CHMA 1T77A 1H10A 1EF1A 1W1DA 1Y5OA 1ZC4B 4EKUA 3FVCA 1KZ7A 1KI1B 1FHXA 4EMOA 2D9ZA 3AU4A 4K2PA 1MAIA 5JHHA 1WJMA 2BCJA 2OTXA 4C0AA 2COFA 3ODWA 2ELAA 2MWNB 2D2QA 4QJ4B 3VOQA 4HAZB 1TXDA 5C79A 2W2XC 5C6RA 2MKRA 2D10A 2UVMA 2YS5A 3BJIA 3SYXA 4ZRKA 5D3WA 1FAOA 1UPRA 4TYZA 2ROZB 3TCAA 2ADZA 1FOEA 4GN1A 2QKLA 2J0MA 4L6EA 3U12A 1V5MA 2J0KA 2DTCA 3AU5A 2IFSA 2MDXA 2M38A 1TQZA 2DYNA 2DX1A 4HAUB 4K2OA 5HE1A 3WYFB 1BTKA 2FJLA 2E2XA 2J59M 2D9VA 4GXBA 3HIEA 2H7EA 2LKOA 1WVHA 3DXDA 3P6AA 4HB3B 2RGNB 1BAKA 1MIXA 3ML4A 3QBVB 3KRXA 2D9WA 1FHOA 1W1GA 1K5GB 3RCPA 2NBVA 2CAYA 2X18A 2K8EA 3A8PA 1UNQA 5IRSA 4GZUA 1WJ1A 5D3VA 3PG7A 4GOUA 3GYOA 3MDBC 2I5FA 4DX8A 1NTYA 1OMWA 2COAA 4KVGB 2AEHA 2YVCA 3TW1A 3CIKA 3U7DA 2YSZA 3A58A 4EJNA 1RRPB 1AQCA 1ZC3B 2EJ8A 2DHIA 2ROVA 2W2WA 4HAWB 2YS3A 4GMXB 1BWNA 3HQCA 3U8ZA 2RLOA 3MPXA 3DCXA 4IOYX 3M1IB 2ELBA 2N23A 2W2XD 1NI2A 2EMTA 3NSUA 2Q13A 3CXBB 5FI1A 2YF0A 1DYNA 2DKPA 2KR0A 2L1CA 3OANA 4DX90 1U5EA 4L1RA 1J19A 2KGXB 4DBBA 2Z14A 3ULCA 3G9WA 4HDQA 2GCJA 4D6WA 3PVLA 2VRWB 2V76A 4KAXB 3O96A 2Z0PA 3PEGA 2IYBA 2Y7BA 2KUPA 5HE0A 3N7CA 2P0DA 5DHFB 1MK7B 2Z59A 3ZDTA 2Z13A 1ISNA 2Z0QA 4NY0A 5M4YB 4MK0A 3AJ4A 5LG4B 4QJ3B 2PZ1A 1J0WA 2KUQA 4F7UP 2RVBB 2VSZA 4WSFA 1M7EA 1X86A 1WG7A 3UZTA 1DROA 3ODOA 2D4QA 2CY5A 5HE2A 4HATB 2NZ8B 3NWDA 4HSIA 2ZPYA 2J0JA
chains in the Genus database with same CATH topology
3ULBA 3SV1A 4K17A 5D27A 4Z2MB 1GG3A 1U5GA 5D3XA 2N0YA 2P0HA 3PVWA 4P7IA 1NTVA 1MIZB 5J3QA 5DH9B 1XODA 4IFSA 2L2IA 3A8QA 2G35A 1V5PA 4HAXB 1U5FA 3LJUX 1RJ2A 1DDWA 4YONA 1QC6A 2DN6A 1SHCA 1KZGA 2MFQA 2RUKB 2LOZA 2D9XA 1B55A 1Y19B 5KQ4A 1FGZA 5J3YA 2Z0OA 3X23A 2UZSA 4ZRIA 5JP4A 3F5RA 4F7HA 4IAPA 4KHAA 4GPTB 1LW3A 5J3TA 1UNPA 1XX0A 2YRYA 3HW2B 3KZ1A 3DXEA 1PLSA 3ODXA 1M7RA 4BBKA 1P3RA 1PFJA 3D8FA 2LYDA 1V61A 2P0FA 2DKQA 1XKEA 2DLWA 4H8SA 4WJ7A 1ZM0A 4A6FA 1U29A 1GC7A 2LOXA 1X05A 2EC1A 1P5TA 1QQGA 1FB8A 5DIFB 5CLQB 3T06A 2JP2A 3PZDA 5CLLB 1V89A 4D0NB 4YL8A 5LONB 2OQBA 1U27A 2LG1A 2D11A 3TO1A 1X1FA 1WGUA 2GJYA 2DHJA 3PP2A 1N3HA 2KCJA 1Q67A 2P8VA 4CYEA 1I7AA 4DXAB 2CODA 4HAVB 5JHGA 4B6HA 3SO6A 1MK9B 4A6FB 2NMBA 2K2JA 2DX5A 4HDOA 5DI9B 4WVFB 3TVVA 1DBHA 1IRSA 4TKNA 1FHWA 1V5UA 4XWXA 2UZRA 2RSGA 5C5BB 5GOWB 4HB0B 3SUZA 5D3YA 1MPHA 1UEFA 4PNKA 3KRWA 1GC6A 2YT0A 1U5DA 4HB2B 1SGHA 3D8EA 1FGYA 2H7DA 5L81A 1OQNA 5EFXA 5FI0A 1XD4A 4Y94A 3PSCA 1EAZA 2RNRB 2DFKA 1W1HA 4HHVA 4HB4B 4Z2NA 2R0DA 5KCVA 1NU2A 1X11A 4K81A 3PVUA 2DYQA 3DXCA 2HE7A 1P6SA 2GS0A 4GMVA 4A6KA 3FSSA 2LULA 2QKMA 2CRFA 3BINA 2R09A 3FEHA 4KHOA 1E5WA 1OY2A 1V88A 2Y8FA 5JLJB 3D8DA 5LOPB 1WGQA 1ZSQA 3HK0A 1XR0B 4A5KA 4MT7A 2I1JA 2I5CA 2YT1A 3P7ZA 3WA0A 4CHJA 1UNRA 2GCLA 5KQ1A 5HE3A 2K2UA 1WI1A 2Y8GA 2EMSA 3F0WA 4A6HA 1H4RA 1EGXA 1DDVA 3SNHA 3IVFA 2M14A 3FM8C 1LB1A 2DHKA 1DDMA 1TJ6A 1K5DB 1AWEA 3A98B 3KSYA 2K00A 1I2HA 1MKEA 5C5BA 3V5WA 1Z87A 4NSWA 4KHBB 4MY6A 2YS1A 5DHAB 4ZRJA 1U2BA 3KY9A 2XQNM 3TFMA 1ZVRA 3QWMA 3GYPA 4PQ0A 4HAYB 1X1GA 5C16A 1EVHA 1UPQA 3ZVRA 2HTHB 2COCA 2D9YA 2AL6A 1BTNA 3VIAA 3QIJA 1XCGA 4F7GA 2DA0A 2CY4A 1PMSA 2I1KA 2VKIA 4CHMA 1H10A 1EF1A 1W1DA 1Y5OA 1ZC4B 4EKUA 1KZ7A 1KI1B 1FHXA 4EMOA 2D9ZA 3AU4A 4K2PA 1MAIA 5JHHA 1WJMA 2BCJA 2OTXA 4C0AA 2COFA 3ODWA 2ELAA 2MWNB 2D2QA 3VOQA 4HAZB 1TXDA 5C79A 2W2XC 5C6RA 2MKRA 2D10A 2UVMA 2YS5A 3BJIA 3SYXA 4ZRKA 5D3WA 1FAOA 1UPRA 4TYZA 2ROZB 3TCAA 2ADZA 1FOEA 4GN1A 2QKLA 2J0MA 4L6EA 1V5MA 2J0KA 2DTCA 3AU5A 2IFSA 2MDXA 2M38A 1TQZA 2DYNA 2DX1A 4HAUB 4K2OA 5HE1A 3WYFB 1BTKA 2FJLA 2E2XA 2J59M 2D9VA 4GXBA 2H7EA 2LKOA 1WVHA 3DXDA 3P6AA 4HB3B 2RGNB 1BAKA 1MIXA 3ML4A 3QBVB 3KRXA 2D9WA 1FHOA 1W1GA 1K5GB 3RCPA 2CAYA 2X18A 3A8PA 1UNQA 4GZUA 1WJ1A 5D3VA 3PG7A 3GYOA 3MDBC 2I5FA 4DX8A 1NTYA 1OMWA 2COAA 4KVGB 2AEHA 2YVCA 3TW1A 3CIKA 3U7DA 2YSZA 4EJNA 1RRPB 1AQCA 1ZC3B 2EJ8A 2DHIA 2ROVA 2W2WA 4HAWB 2YS3A 4GMXB 1BWNA 3HQCA 3U8ZA 2RLOA 3MPXA 4IOYX 3M1IB 2ELBA 2N23A 2W2XD 1NI2A 2EMTA 3NSUA 2Q13A 3CXBB 5FI1A 2YF0A 1DYNA 2DKPA 2L1CA 3OANA 4DX90 1U5EA 1J19A 2KGXB 4DBBA 3ULCA 3G9WA 4HDQA 2GCJA 3PVLA 2VRWB 2V76A 4KAXB 3O96A 2Z0PA 3PEGA 2IYBA 2Y7BA 2KUPA 5HE0A 3N7CA 2P0DA 5DHFB 1MK7B 3ZDTA 1ISNA 2Z0QA 4NY0A 4MK0A 3AJ4A 2PZ1A 1J0WA 4F7UP 2RVBB 2VSZA 4WSFA 1M7EA 1X86A 1WG7A 3UZTA 1DROA 3ODOA 2D4QA 2CY5A 5HE2A 4HATB 2NZ8B 2ZPYA 2J0JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ULB A;  3SV1 A;  4K17 A;  5D27 A;  4Z2M B;  1GG3 A;  1U5G A;  5D3X A;  2N0Y A;  2P0H A;  3PVW A;  4P7I A;  1NTV A;  1MIZ B;  5J3Q A;  5DH9 B;  1XOD A;  4IFS A;  2L2I A;  3A8Q A;  2G35 A;  1V5P A;  4HAX B;  1U5F A;  3LJU X;  1RJ2 A;  1DDW A;  4YON A;  1QC6 A;  2DN6 A;  1SHC A;  1KZG A;  2MFQ A;  2RUK B;  2LOZ A;  2D9X A;  1B55 A;  1Y19 B;  5KQ4 A;  1FGZ A;  5J3Y A;  2Z0O A;  3X23 A;  2UZS A;  4ZRI A;  5JP4 A;  3F5R A;  4F7H A;  4IAP A;  4KHA A;  4GPT B;  1LW3 A;  5J3T A;  1UNP A;  1XX0 A;  2YRY A;  3HW2 B;  3KZ1 A;  3DXE A;  1PLS A;  3ODX A;  1M7R A;  4BBK A;  1P3R A;  1PFJ A;  3D8F A;  2LYD A;  1V61 A;  2P0F A;  2DKQ A;  1XKE A;  2DLW A;  4H8S A;  4WJ7 A;  1ZM0 A;  4A6F A;  1U29 A;  1GC7 A;  2LOX A;  1X05 A;  2EC1 A;  1P5T A;  1QQG A;  1FB8 A;  5DIF B;  5CLQ B;  3T06 A;  2JP2 A;  3PZD A;  5CLL B;  1V89 A;  4D0N B;  4YL8 A;  5LON B;  2OQB A;  1U27 A;  2LG1 A;  2D11 A;  3TO1 A;  1X1F A;  1WGU A;  2GJY A;  2DHJ A;  3PP2 A;  1N3H A;  2KCJ A;  1Q67 A;  2P8V A;  4CYE A;  1I7A A;  4DXA B;  2COD A;  4HAV B;  5JHG A;  4B6H A;  3SO6 A;  1MK9 B;  4A6F B;  2NMB A;  2K2J A;  2DX5 A;  4HDO A;  5DI9 B;  4WVF B;  3TVV A;  1DBH A;  1IRS A;  4TKN A;  1FHW A;  1V5U A;  4XWX A;  2UZR A;  2RSG A;  5C5B B;  5GOW B;  4HB0 B;  3SUZ A;  5D3Y A;  1MPH A;  1UEF A;  4PNK A;  3KRW A;  1GC6 A;  2YT0 A;  1U5D A;  4HB2 B;  1SGH A;  3D8E A;  1FGY A;  2H7D A;  5L81 A;  1OQN A;  5EFX A;  5FI0 A;  1XD4 A;  4Y94 A;  3PSC A;  1EAZ A;  2RNR B;  2DFK A;  1W1H A;  4HHV A;  4HB4 B;  4Z2N A;  2R0D A;  5KCV A;  1NU2 A;  1X11 A;  4K81 A;  3PVU A;  2DYQ A;  3DXC A;  2HE7 A;  1P6S A;  2GS0 A;  4GMV A;  4A6K A;  3FSS A;  2LUL A;  2QKM A;  2CRF A;  3BIN A;  2R09 A;  3FEH A;  4KHO A;  1E5W A;  1OY2 A;  1V88 A;  2Y8F A;  5JLJ B;  3D8D A;  5LOP B;  1WGQ A;  1ZSQ A;  3HK0 A;  1XR0 B;  4A5K A;  4MT7 A;  2I1J A;  2I5C A;  2YT1 A;  3P7Z A;  3WA0 A;  4CHJ A;  1UNR A;  2GCL A;  5KQ1 A;  5HE3 A;  2K2U A;  1WI1 A;  2Y8G A;  2EMS A;  3F0W A;  4A6H A;  1H4R A;  1EGX A;  1DDV A;  3SNH A;  3IVF A;  2M14 A;  3FM8 C;  1LB1 A;  2DHK A;  1DDM A;  1TJ6 A;  1K5D B;  1AWE A;  3A98 B;  3KSY A;  2K00 A;  1I2H A;  1MKE A;  5C5B A;  3V5W A;  1Z87 A;  4NSW A;  4KHB B;  4MY6 A;  2YS1 A;  5DHA B;  4ZRJ A;  1U2B A;  3KY9 A;  2XQN M;  3TFM A;  1ZVR A;  3QWM A;  3GYP A;  4PQ0 A;  4HAY B;  1X1G A;  5C16 A;  1EVH A;  1UPQ A;  3ZVR A;  2HTH B;  2COC A;  2D9Y A;  2AL6 A;  1BTN A;  3VIA A;  3QIJ A;  1XCG A;  4F7G A;  2DA0 A;  2CY4 A;  1PMS A;  2I1K A;  2VKI A;  4CHM A;  1H10 A;  1EF1 A;  1W1D A;  1Y5O A;  1ZC4 B;  4EKU A;  1KZ7 A;  1KI1 B;  1FHX A;  4EMO A;  2D9Z A;  3AU4 A;  4K2P A;  1MAI A;  5JHH A;  1WJM A;  2BCJ A;  2OTX A;  4C0A A;  2COF A;  3ODW A;  2ELA A;  2MWN B;  2D2Q A;  3VOQ A;  4HAZ B;  1TXD A;  5C79 A;  2W2X C;  5C6R A;  2MKR A;  2D10 A;  2UVM A;  2YS5 A;  3BJI A;  3SYX A;  4ZRK A;  5D3W A;  1FAO A;  1UPR A;  4TYZ A;  2ROZ B;  3TCA A;  2ADZ A;  1FOE A;  4GN1 A;  2QKL A;  2J0M A;  4L6E A;  1V5M A;  2J0K A;  2DTC A;  3AU5 A;  2IFS A;  2MDX A;  2M38 A;  1TQZ A;  2DYN A;  2DX1 A;  4HAU B;  4K2O A;  5HE1 A;  3WYF B;  1BTK A;  2FJL A;  2E2X A;  2J59 M;  2D9V A;  4GXB A;  2H7E A;  2LKO A;  1WVH A;  3DXD A;  3P6A A;  4HB3 B;  2RGN B;  1BAK A;  1MIX A;  3ML4 A;  3QBV B;  3KRX A;  2D9W A;  1FHO A;  1W1G A;  1K5G B;  3RCP A;  2CAY A;  2X18 A;  3A8P A;  1UNQ A;  4GZU A;  1WJ1 A;  5D3V A;  3PG7 A;  3GYO A;  3MDB C;  2I5F A;  4DX8 A;  1NTY A;  1OMW A;  2COA A;  4KVG B;  2AEH A;  2YVC A;  3TW1 A;  3CIK A;  3U7D A;  2YSZ A;  4EJN A;  1RRP B;  1AQC A;  1ZC3 B;  2EJ8 A;  2DHI A;  2ROV A;  2W2W A;  4HAW B;  2YS3 A;  4GMX B;  1BWN A;  3HQC A;  3U8Z A;  2RLO A;  3MPX A;  4IOY X;  3M1I B;  2ELB A;  2N23 A;  2W2X D;  1NI2 A;  2EMT A;  3NSU A;  2Q13 A;  3CXB B;  5FI1 A;  2YF0 A;  1DYN A;  2DKP A;  2L1C A;  3OAN A;  4DX9 0;  1U5E A;  1J19 A;  2KGX B;  4DBB A;  3ULC A;  3G9W A;  4HDQ A;  2GCJ A;  3PVL A;  2VRW B;  2V76 A;  4KAX B;  3O96 A;  2Z0P A;  3PEG A;  2IYB A;  2Y7B A;  2KUP A;  5HE0 A;  3N7C A;  2P0D A;  5DHF B;  1MK7 B;  3ZDT A;  1ISN A;  2Z0Q A;  4NY0 A;  4MK0 A;  3AJ4 A;  2PZ1 A;  1J0W A;  4F7U P;  2RVB B;  2VSZ A;  4WSF A;  1M7E A;  1X86 A;  1WG7 A;  3UZT A;  1DRO A;  3ODO A;  2D4Q A;  2CY5 A;  5HE2 A;  4HAT B;  2NZ8 B;  2ZPY A;  2J0J A; 
#chains in the Genus database with same CATH topology
 3ULB A;  3SV1 A;  4K17 A;  5D27 A;  4Z2M B;  1GG3 A;  1U5G A;  5D3X A;  2N0Y A;  2P0H A;  3PVW A;  4P7I A;  1NTV A;  1MIZ B;  5J3Q A;  4GNK B;  5DH9 B;  1XOD A;  4IFS A;  2L2I A;  3A8Q A;  2G35 A;  1V5P A;  4HAX B;  1U5F A;  3LJU X;  1RJ2 A;  1DDW A;  4YON A;  1QC6 A;  2DN6 A;  5I2S A;  1SHC A;  1KZG A;  2MFQ A;  2RUK B;  2LOZ A;  2D9X A;  1B55 A;  1Y19 B;  5KQ4 A;  1FGZ A;  5I2M A;  5J3Y A;  2Z0O A;  3X23 A;  2UZS A;  4ZRI A;  5JP4 A;  3F5R A;  4F7H A;  2GUM A;  4IAP A;  4KHA A;  4GPT B;  1LW3 A;  5J3T A;  1UNP A;  1XX0 A;  2YRY A;  2K49 A;  2YT2 A;  3HW2 B;  3KZ1 A;  3DXE A;  1PLS A;  3ODX A;  1M7R A;  4BBK A;  1P3R A;  1PFJ A;  3D8F A;  2LYD A;  1V61 A;  2P0F A;  2DKQ A;  1XKE A;  2DLW A;  4H8S A;  4WJ7 A;  1ZM0 A;  4A6F A;  1U29 A;  1GC7 A;  2LOX A;  1X05 A;  2EC1 A;  2Z4D A;  1P5T A;  1QQG A;  1FB8 A;  5DIF B;  5CLQ B;  3T06 A;  2JP2 A;  3PZD A;  5CLL B;  1V89 A;  4D0N B;  4YL8 A;  5LON B;  2OQB A;  1U27 A;  2LG1 A;  2D11 A;  3TO1 A;  1X1F A;  1WGU A;  2GJY A;  2DHJ A;  3PP2 A;  1N3H A;  2KCJ A;  4CSQ A;  1Q67 A;  2P8V A;  4CYE A;  3NW8 A;  1I7A A;  4DXA B;  2COD A;  4HAV B;  5JHG A;  4B6H A;  3NWF A;  3SO6 A;  1MK9 B;  4A6F B;  2NMB A;  2K2J A;  2DX5 A;  4HDO A;  5DI9 B;  4QXA B;  4WVF B;  3TVV A;  1DBH A;  1IRS A;  4TKN A;  1FHW A;  1V5U A;  4XWX A;  4DIX A;  2UZR A;  2RSG A;  5C5B B;  5GOW B;  4HB0 B;  2KIE A;  3SUZ A;  5D3Y A;  2ZKM X;  3HSA A;  1MPH A;  1UEF A;  4PNK A;  3KRW A;  1GC6 A;  2YT0 A;  2KIG A;  1U5D A;  4HB2 B;  1SGH A;  3D8E A;  1FGY A;  2H7D A;  5L81 A;  1OQN A;  5EFX A;  5FI0 A;  4QJ5 B;  1XD4 A;  4Y94 A;  3PSC A;  1EAZ A;  3B77 A;  2RNR B;  2DFK A;  1W1H A;  4HHV A;  4HB4 B;  4Z2N A;  2R0D A;  5KCV A;  1NU2 A;  1X11 A;  4K81 A;  4OSN A;  3PVU A;  2DYQ A;  3DXC A;  2HE7 A;  1P6S A;  2RRF A;  2GS0 A;  4GMV A;  4A6K A;  1MI1 A;  3FSS A;  2LUL A;  2QKM A;  4OT1 A;  2CRF A;  3BIN A;  2R09 A;  3FEH A;  4KHO A;  1E5W A;  1OY2 A;  1V88 A;  2Y8F A;  5JLJ B;  3D8D A;  5LOP B;  1WGQ A;  1ZSQ A;  3HK0 A;  1XR0 B;  4A5K A;  4KHB A;  4MT7 A;  2I1J A;  2I5C A;  1ZYI A;  2YT1 A;  3P7Z A;  3WA0 A;  4CHJ A;  1UNR A;  2GCL A;  2FJU B;  5KQ1 A;  2R2Y A;  5HE3 A;  2K2U A;  1WI1 A;  2Y8G A;  2EMS A;  3F0W A;  4A6H A;  1H4R A;  1EGX A;  1DDV A;  3SNH A;  3IVF A;  2M14 A;  3FM8 C;  1LB1 A;  2DHK A;  1DDM A;  1TJ6 A;  1K5D B;  1AWE A;  3A98 B;  3KSY A;  2K00 A;  1I2H A;  1MKE A;  5C5B A;  3V5W A;  1Z87 A;  4NSW A;  4KHB B;  4MY6 A;  2YS1 A;  5DHA B;  4ZRJ A;  1U2B A;  3KY9 A;  2XQN M;  3TFM A;  1ZVR A;  3QWM A;  3GYP A;  4PQ0 A;  3NWA A;  4HAY B;  1X1G A;  5C16 A;  1EVH A;  1UPQ A;  3ZVR A;  2HTH B;  2COC A;  2D9Y A;  2AL6 A;  1BTN A;  3VIA A;  3QIJ A;  3OHM B;  1XCG A;  4F7G A;  2DA0 A;  2CY4 A;  1PMS A;  2I1K A;  2VKI A;  4CHM A;  1T77 A;  1H10 A;  1EF1 A;  1W1D A;  1Y5O A;  1ZC4 B;  4EKU A;  3FVC A;  1KZ7 A;  1KI1 B;  1FHX A;  4EMO A;  2D9Z A;  3AU4 A;  4K2P A;  1MAI A;  5JHH A;  1WJM A;  2BCJ A;  2OTX A;  4C0A A;  2COF A;  3ODW A;  2ELA A;  2MWN B;  2D2Q A;  4QJ4 B;  3VOQ A;  4HAZ B;  1TXD A;  5C79 A;  2W2X C;  5C6R A;  2MKR A;  2D10 A;  2UVM A;  2YS5 A;  3BJI A;  3SYX A;  4ZRK A;  5D3W A;  1FAO A;  1UPR A;  4TYZ A;  2ROZ B;  3TCA A;  2ADZ A;  1FOE A;  4GN1 A;  2QKL A;  2J0M A;  4L6E A;  3U12 A;  1V5M A;  2J0K A;  2DTC A;  3AU5 A;  2IFS A;  2MDX A;  2M38 A;  1TQZ A;  2DYN A;  2DX1 A;  4HAU B;  4K2O A;  5HE1 A;  3WYF B;  1BTK A;  2FJL A;  2E2X A;  2J59 M;  2D9V A;  4GXB A;  3HIE A;  2H7E A;  2LKO A;  1WVH A;  3DXD A;  3P6A A;  4HB3 B;  2RGN B;  1BAK A;  1MIX A;  3ML4 A;  3QBV B;  3KRX A;  2D9W A;  1FHO A;  1W1G A;  1K5G B;  3RCP A;  2NBV A;  2CAY A;  2X18 A;  2K8E A;  3A8P A;  1UNQ A;  5IRS A;  4GZU A;  1WJ1 A;  5D3V A;  3PG7 A;  4GOU A;  3GYO A;  3MDB C;  2I5F A;  4DX8 A;  1NTY A;  1OMW A;  2COA A;  4KVG B;  2AEH A;  2YVC A;  3TW1 A;  3CIK A;  3U7D A;  2YSZ A;  3A58 A;  4EJN A;  1RRP B;  1AQC A;  1ZC3 B;  2EJ8 A;  2DHI A;  2ROV A;  2W2W A;  4HAW B;  2YS3 A;  4GMX B;  1BWN A;  3HQC A;  3U8Z A;  2RLO A;  3MPX A;  3DCX A;  4IOY X;  3M1I B;  2ELB A;  2N23 A;  2W2X D;  1NI2 A;  2EMT A;  3NSU A;  2Q13 A;  3CXB B;  5FI1 A;  2YF0 A;  1DYN A;  2DKP A;  2KR0 A;  2L1C A;  3OAN A;  4DX9 0;  1U5E A;  4L1R A;  1J19 A;  2KGX B;  4DBB A;  2Z14 A;  3ULC A;  3G9W A;  4HDQ A;  2GCJ A;  4D6W A;  3PVL A;  2VRW B;  2V76 A;  4KAX B;  3O96 A;  2Z0P A;  3PEG A;  2IYB A;  2Y7B A;  2KUP A;  5HE0 A;  3N7C A;  2P0D A;  5DHF B;  1MK7 B;  2Z59 A;  3ZDT A;  2Z13 A;  1ISN A;  2Z0Q A;  4NY0 A;  5M4Y B;  4MK0 A;  3AJ4 A;  5LG4 B;  4QJ3 B;  2PZ1 A;  1J0W A;  2KUQ A;  4F7U P;  2RVB B;  2VSZ A;  4WSF A;  1M7E A;  1X86 A;  1WG7 A;  3UZT A;  1DRO A;  3ODO A;  2D4Q A;  2CY5 A;  5HE2 A;  4HAT B;  2NZ8 B;  3NWD A;  4HSI A;  2ZPY A;  2J0J A; 
#chains in the Genus database with same CATH homology
 3ULB A;  3SV1 A;  4K17 A;  5D27 A;  4Z2M B;  1GG3 A;  1U5G A;  5D3X A;  2N0Y A;  2P0H A;  3PVW A;  4P7I A;  1NTV A;  1MIZ B;  5J3Q A;  5DH9 B;  1XOD A;  4IFS A;  2L2I A;  3A8Q A;  2G35 A;  1V5P A;  4HAX B;  1U5F A;  3LJU X;  1RJ2 A;  1DDW A;  4YON A;  1QC6 A;  2DN6 A;  1SHC A;  1KZG A;  2MFQ A;  2RUK B;  2LOZ A;  2D9X A;  1B55 A;  1Y19 B;  5KQ4 A;  1FGZ A;  5J3Y A;  2Z0O A;  3X23 A;  2UZS A;  4ZRI A;  5JP4 A;  3F5R A;  4F7H A;  4IAP A;  4KHA A;  4GPT B;  1LW3 A;  5J3T A;  1UNP A;  1XX0 A;  2YRY A;  3HW2 B;  3KZ1 A;  3DXE A;  1PLS A;  3ODX A;  1M7R A;  4BBK A;  1P3R A;  1PFJ A;  3D8F A;  2LYD A;  1V61 A;  2P0F A;  2DKQ A;  1XKE A;  2DLW A;  4H8S A;  4WJ7 A;  1ZM0 A;  4A6F A;  1U29 A;  1GC7 A;  2LOX A;  1X05 A;  2EC1 A;  1P5T A;  1QQG A;  1FB8 A;  5DIF B;  5CLQ B;  3T06 A;  2JP2 A;  3PZD A;  5CLL B;  1V89 A;  4D0N B;  4YL8 A;  5LON B;  2OQB A;  1U27 A;  2LG1 A;  2D11 A;  3TO1 A;  1X1F A;  1WGU A;  2GJY A;  2DHJ A;  3PP2 A;  1N3H A;  2KCJ A;  1Q67 A;  2P8V A;  4CYE A;  1I7A A;  4DXA B;  2COD A;  4HAV B;  5JHG A;  4B6H A;  3SO6 A;  1MK9 B;  4A6F B;  2NMB A;  2K2J A;  2DX5 A;  4HDO A;  5DI9 B;  4WVF B;  3TVV A;  1DBH A;  1IRS A;  4TKN A;  1FHW A;  1V5U A;  4XWX A;  2UZR A;  2RSG A;  5C5B B;  5GOW B;  4HB0 B;  3SUZ A;  5D3Y A;  1MPH A;  1UEF A;  4PNK A;  3KRW A;  1GC6 A;  2YT0 A;  1U5D A;  4HB2 B;  1SGH A;  3D8E A;  1FGY A;  2H7D A;  5L81 A;  1OQN A;  5EFX A;  5FI0 A;  1XD4 A;  4Y94 A;  3PSC A;  1EAZ A;  2RNR B;  2DFK A;  1W1H A;  4HHV A;  4HB4 B;  4Z2N A;  2R0D A;  5KCV A;  1NU2 A;  1X11 A;  4K81 A;  3PVU A;  2DYQ A;  3DXC A;  2HE7 A;  1P6S A;  2GS0 A;  4GMV A;  4A6K A;  3FSS A;  2LUL A;  2QKM A;  2CRF A;  3BIN A;  2R09 A;  3FEH A;  4KHO A;  1E5W A;  1OY2 A;  1V88 A;  2Y8F A;  5JLJ B;  3D8D A;  5LOP B;  1WGQ A;  1ZSQ A;  3HK0 A;  1XR0 B;  4A5K A;  4MT7 A;  2I1J A;  2I5C A;  2YT1 A;  3P7Z A;  3WA0 A;  4CHJ A;  1UNR A;  2GCL A;  5KQ1 A;  5HE3 A;  2K2U A;  1WI1 A;  2Y8G A;  2EMS A;  3F0W A;  4A6H A;  1H4R A;  1EGX A;  1DDV A;  3SNH A;  3IVF A;  2M14 A;  3FM8 C;  1LB1 A;  2DHK A;  1DDM A;  1TJ6 A;  1K5D B;  1AWE A;  3A98 B;  3KSY A;  2K00 A;  1I2H A;  1MKE A;  5C5B A;  3V5W A;  1Z87 A;  4NSW A;  4KHB B;  4MY6 A;  2YS1 A;  5DHA B;  4ZRJ A;  1U2B A;  3KY9 A;  2XQN M;  3TFM A;  1ZVR A;  3QWM A;  3GYP A;  4PQ0 A;  4HAY B;  1X1G A;  5C16 A;  1EVH A;  1UPQ A;  3ZVR A;  2HTH B;  2COC A;  2D9Y A;  2AL6 A;  1BTN A;  3VIA A;  3QIJ A;  1XCG A;  4F7G A;  2DA0 A;  2CY4 A;  1PMS A;  2I1K A;  2VKI A;  4CHM A;  1H10 A;  1EF1 A;  1W1D A;  1Y5O A;  1ZC4 B;  4EKU A;  1KZ7 A;  1KI1 B;  1FHX A;  4EMO A;  2D9Z A;  3AU4 A;  4K2P A;  1MAI A;  5JHH A;  1WJM A;  2BCJ A;  2OTX A;  4C0A A;  2COF A;  3ODW A;  2ELA A;  2MWN B;  2D2Q A;  3VOQ A;  4HAZ B;  1TXD A;  5C79 A;  2W2X C;  5C6R A;  2MKR A;  2D10 A;  2UVM A;  2YS5 A;  3BJI A;  3SYX A;  4ZRK A;  5D3W A;  1FAO A;  1UPR A;  4TYZ A;  2ROZ B;  3TCA A;  2ADZ A;  1FOE A;  4GN1 A;  2QKL A;  2J0M A;  4L6E A;  1V5M A;  2J0K A;  2DTC A;  3AU5 A;  2IFS A;  2MDX A;  2M38 A;  1TQZ A;  2DYN A;  2DX1 A;  4HAU B;  4K2O A;  5HE1 A;  3WYF B;  1BTK A;  2FJL A;  2E2X A;  2J59 M;  2D9V A;  4GXB A;  2H7E A;  2LKO A;  1WVH A;  3DXD A;  3P6A A;  4HB3 B;  2RGN B;  1BAK A;  1MIX A;  3ML4 A;  3QBV B;  3KRX A;  2D9W A;  1FHO A;  1W1G A;  1K5G B;  3RCP A;  2CAY A;  2X18 A;  3A8P A;  1UNQ A;  4GZU A;  1WJ1 A;  5D3V A;  3PG7 A;  3GYO A;  3MDB C;  2I5F A;  4DX8 A;  1NTY A;  1OMW A;  2COA A;  4KVG B;  2AEH A;  2YVC A;  3TW1 A;  3CIK A;  3U7D A;  2YSZ A;  4EJN A;  1RRP B;  1AQC A;  1ZC3 B;  2EJ8 A;  2DHI A;  2ROV A;  2W2W A;  4HAW B;  2YS3 A;  4GMX B;  1BWN A;  3HQC A;  3U8Z A;  2RLO A;  3MPX A;  4IOY X;  3M1I B;  2ELB A;  2N23 A;  2W2X D;  1NI2 A;  2EMT A;  3NSU A;  2Q13 A;  3CXB B;  5FI1 A;  2YF0 A;  1DYN A;  2DKP A;  2L1C A;  3OAN A;  4DX9 0;  1U5E A;  1J19 A;  2KGX B;  4DBB A;  3ULC A;  3G9W A;  4HDQ A;  2GCJ A;  3PVL A;  2VRW B;  2V76 A;  4KAX B;  3O96 A;  2Z0P A;  3PEG A;  2IYB A;  2Y7B A;  2KUP A;  5HE0 A;  3N7C A;  2P0D A;  5DHF B;  1MK7 B;  3ZDT A;  1ISN A;  2Z0Q A;  4NY0 A;  4MK0 A;  3AJ4 A;  2PZ1 A;  1J0W A;  4F7U P;  2RVB B;  2VSZ A;  4WSF A;  1M7E A;  1X86 A;  1WG7 A;  3UZT A;  1DRO A;  3ODO A;  2D4Q A;  2CY5 A;  5HE2 A;  4HAT B;  2NZ8 B;  2ZPY A;  2J0J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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