2Z2DA

Solution structure of human macrophage elastase (mmp-12) catalytic domain complexed with a gamma-keto butanoic acid inhibitor
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of human macrophage elastase (MMP-12) catalytic domain complexed with a gamma-keto butanoic acid inhibitor
rcsb
molecule keywords Macrophage metalloelastase
molecule tags Hydrolase
source organism Homo sapiens
total genus 25
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2007-05-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2z2dA00
1SU3A 2AYKA 3EDGA 4H1QA 5L7FA 3V96B 1YQYA 3VI1A 2D1OA 3ZVSA 1FBLA 1JIZA 4XM8A 3TVCA 1G4KA 3VTGA 3N2VA 1O0QA 1ZXVA 4I03A 1G05A 1QUAA 2Z2DA 3DPFA 4HX3A 2XS3A 3B2ZA 4L19A 1HY7A 4L6TA 1D8FA 1I1IP 1MMPA 1CGFA 3N2UA 3KEKA 3LILA 3UVCA 1R1HA 1G9KA 4ON1A 2RJQA 1PWUA 3LJGA 4JP4A 1D5JA 3WV2A 1KUGA 5CUHA 3DSLA 1D7XA 4PKWA 1GO8P 4XCTA 2JT6A 1CAQA 1XFUA 4R3VA 1GE5A 1QJJA 4H76A 3HY7A 2MZEA 2I47A 3HDAP 5D7WA 1GE7A 5BOTA 3LQ0A 4PKUA 4GF1A 3P24A 1YCMA 1EUBA 1HOVA 1JK3A 2OVXA 4JPAA 4GR3A 3KHIA 2D1NA 3KECA 2K9CA 1R55A 2JIHA 1Y93A 2YIGA 4L63A 4PKTA 4HMAA 2OI0A 4A7BA 2FV9A 5D3CA 1B8YA 1MMQA 3TS4A 2WOAA 4I35A 1G12A 1C8TA 1RMZA 4IUWA 1XFVA 2YB9A 3HBUP 3EDHA 3LQBA 3O64A 1IACA 3Q2HA 3HBVP 1BIWA 2W0DA 3DPEA 3LUNA 3MA2A 1XURA 1H71P 830CA 1IAAA 1GO7P 1ZXCA 5L79A 4WF6A 2DW1A 1UMSA 3F18A 1USNA 3LUMA 3LMCA 1QIAA 3ZUKA 1IADA 1PWVA 1OM8A 4J4MA 1BUDA 1XFWA 4JA1A 3GBOA 1AYKA 4WK7A 3U1RA 1CQRA 2HU6A 4GQLA 1CGLA 4IN9A 1C7KA 3K7NA 4FVLA 966CA 2W12A 4G9LA 2AIGP 2W13A 3WV1A 2MLRA 4JQGA 3L0TA 3ZXHA 1ROSA 1CXVA 4H84A 3B92A 1KUFA 1AF0A 2ERQA 4IJOA 1YP1A 2X7MA 1BQOA 1KUHA 3G42A 4H49A 4GWMA 1UTTA 5H8XA 3EDZA 1Y8JA 2KRJA 1EB6A 1YOUA 1ATLA 3LE9A 2Y6DA 3ELMA 4GUYA 4ZR5A 2J83A 3I7IA 5I4OA 2OVZA 1J7NA 3HB2P 1KUIA 1AKLA 4AUOA 2WO9A 1XFXA 1BSWA 3EHXA 3KMEA 2SRTA 1BUVM 2OZRA 2FV5A 3LK8A 1QJIA 4WKIA 4AXQA 2EROA 3HY9A 2X3AA 1PWWA 1G49A 1L6JA 4DF9A 5D2BA 1O0TA 4PKQA 5B5OA 1JAOA 1DTHA 4FU4A 1BM6A 1K7QA 1HTDA 3K7LA 2OY2A 4PKVA 1SLNA 2USNA 1R1IA 5I2ZA 1XUDA 3RTTA 2L0RA 2E2DA 4G0DA 2XS4A 3F19A 1BKCE 5CZMA 1OMJA 3F15A 4FXQA 1A85A 1OO9A 3HYGA 3BA0A 1GE6A 3E8RA 3HDBA 3CKIA 4DPEA 3Q2GA 4H3XA 3AIGA 2OXWA 4DV8A 1DMTA 1UMTA 2RJPA 2OW2A 1IABA 5CXAA 4Q1LA 2W15A 3OHOA 2QPJA 5D1UA 1KUKA 3KRYA 3LEAA 1FLSA 2Y6CA 1A86A 1K7GA 1OM6A 3F1AA 1GKCA 1ZVXA 1I73A 3KWVC 4GR8A 1ZTQA 1MNCA 3I7GA 4QKZA 3WV3A 1JIWP 1XFZA 2O36A 1WNIA 2OXZA 2JT5A 1R54A 2PJTA 1ND1A 1JH1A 5LABA 2DW0A 1ZP5A 3DL1A 1FM1A 1CGEA 3EWJA 3USNA 1Y0VA 2A8HA 3L0VA 2W14A 4EFSA 4AIGA 2ERPA 3P1VA 2V4BA 4PKRA 3TT4A 1OS9A 3AYUA 1BZSA 3EHYA 2N8RA 2MZHA 1B3DA 3G5CA 2CKIA 4XM6A 3NX7A 2OXUA 2E3XA 1HFCA 4XM7A 1D8MA 1GKDA 1IAGA 4GR0A 1I76A 4GWNA 4FXYP 5BOYA 4DD8A 2DDFA 2JSDA 4WZVA 1UTZA 1IAEA 1OS2A 1MMBA 3LIKA 3LIRA 4A3WA 1CK7A 4H2EA 1SMPA 2OW0A 4WKEA 3DNGA 1K7IA 3DWBA 1EAKA 1KBCA 1Z3JA 5JMYA 3RTSA 3B8ZA 4CTHA 1S4BP 2J0TA 1OM7A 1QIBA 2TCLA 1JANA 1JAPA 1GXDA 2X3CA 4JIJA 1PWQA 3KEJA 1ASTA 2CLTA 1Q3AA 1CIZA 3OHLA 5D1SA 1MMRA 1SATA 4H30A 2OY4A 5BPAA 4ILWD 1PWPA 1HV5A 1XFYA 1C3IA 2JNPA 3LKAA 3SHIA 4AYKA 2OW1A 1JKYA 2DW2A 5I0LA 1ZS0A 1BKCI 3AYKA 2MZIA 5B5PA 5I43A 5I3MA 2OW9A 1BKCA 2K2GA 1R1JA 2POJA 4PKSA 3F16A 4XBHA 1BQQM 3LJTA 2O3EA 3TSKA 3F17A 5I12A 3LJZA 1XUCA 1RM8A 1JAQA 4H82A 1UEAA 2WO8A 2X3BA 3O2XA 3EDIA 3LGPA 2DDYA 1KAPP 3KMCA 5D1TA 456CA 1QICA 1SLMA 1SRPA 1HFSA 1JJ9A 2MLSA
chains in the Genus database with same CATH superfamily
1SU3A 2AYKA 3EDGA 4H1QA 5L7FA 3V96B 1YQYA 3VI1A 2D1OA 3ZVSA 1FBLA 1JIZA 4XM8A 3TVCA 1G4KA 3VTGA 3N2VA 1O0QA 1ZXVA 4I03A 1G05A 1QUAA 2Z2DA 3DPFA 4HX3A 2XS3A 3B2ZA 4L19A 1HY7A 4L6TA 1D8FA 1I1IP 1MMPA 1CGFA 3N2UA 3KEKA 3LILA 3UVCA 1R1HA 1G9KA 4ON1A 2RJQA 1PWUA 3LJGA 4JP4A 1D5JA 3WV2A 1KUGA 5CUHA 3DSLA 1D7XA 4PKWA 1GO8P 4XCTA 2JT6A 1CAQA 1XFUA 4R3VA 1GE5A 1QJJA 4H76A 3HY7A 2MZEA 2I47A 3HDAP 5D7WA 1GE7A 5BOTA 3DTIA 3LQ0A 4PKUA 4GF1A 3P24A 1YCMA 1EUBA 1HOVA 1JK3A 2OVXA 4JPAA 4GR3A 3KHIA 2D1NA 3KECA 2K9CA 1R55A 2JIHA 1Y93A 2YIGA 4L63A 4PKTA 4HMAA 2OI0A 4A7BA 2FV9A 5D3CA 1B8YA 1MMQA 3TS4A 2WOAA 4I35A 1G12A 1C8TA 1RMZA 4IUWA 1XFVA 2YB9A 3HBUP 3EDHA 3LQBA 3O64A 1XAXA 1IACA 3Q2HA 3HBVP 1BIWA 2W0DA 3DPEA 3LUNA 3MA2A 1XURA 1H71P 830CA 1IAAA 1GO7P 1ZXCA 5L79A 4WF6A 2DW1A 1UMSA 3F18A 1USNA 3LUMA 3LMCA 1QIAA 3ZUKA 1IADA 1PWVA 1OM8A 4J4MA 1BUDA 1XFWA 4JA1A 3GBOA 1AYKA 4WK7A 3U1RA 1CQRA 2HU6A 4GQLA 1CGLA 4IN9A 1C7KA 3K7NA 4FVLA 2YUFA 966CA 2W12A 4G9LA 2AIGP 2W13A 3WV1A 2MLRA 4JQGA 3L0TA 3ZXHA 1ROSA 1CXVA 4H84A 3B92A 1KUFA 1AF0A 2ERQA 4IJOA 1YP1A 2X7MA 1BQOA 1KUHA 3DTKA 3G42A 4H49A 4GWMA 1UTTA 5H8XA 3EDZA 1Y8JA 2KRJA 1EB6A 1YOUA 1ATLA 3LE9A 2Y6DA 3ELMA 4GUYA 4ZR5A 2J83A 3I7IA 5I4OA 2OVZA 1J7NA 3HB2P 1KUIA 1AKLA 4AUOA 2WO9A 1XFXA 1BSWA 1XM5A 3EHXA 3KMEA 2SRTA 1BUVM 2OZRA 2FV5A 3LK8A 1QJIA 4WKIA 4AXQA 2EROA 3HY9A 2X3AA 1PWWA 1G49A 1L6JA 4DF9A 5D2BA 1O0TA 4PKQA 5B5OA 1JAOA 1DTHA 4FU4A 1BM6A 1K7QA 1HTDA 3K7LA 2OY2A 4PKVA 1SLNA 2USNA 1R1IA 5I2ZA 1XUDA 3RTTA 2L0RA 2E2DA 4G0DA 2XS4A 3F19A 1BKCE 5CZMA 1OMJA 3F15A 4FXQA 1A85A 1OO9A 3HYGA 3BA0A 1GE6A 3E8RA 3HDBA 3CKIA 4DPEA 3Q2GA 4H3XA 3AIGA 2OXWA 4DV8A 1DMTA 1UMTA 2RJPA 2OW2A 1IABA 5CXAA 4Q1LA 2W15A 3OHOA 2QPJA 5D1UA 1KUKA 3KRYA 3LEAA 1FLSA 2Y6CA 1A86A 1K7GA 1OM6A 3F1AA 1GKCA 1ZVXA 1I73A 3KWVC 4GR8A 1ZTQA 1MNCA 3I7GA 4QKZA 3WV3A 1JIWP 1XFZA 2O36A 1WNIA 2OXZA 2JT5A 1R54A 2PJTA 1ND1A 1JH1A 5LABA 2DW0A 1ZP5A 3DL1A 1OZ9A 1FM1A 1CGEA 3EWJA 3USNA 1Y0VA 2A8HA 3L0VA 1TVIA 2W14A 4EFSA 4AIGA 2ERPA 3P1VA 2V4BA 4PKRA 3TT4A 1OS9A 3AYUA 1BZSA 3EHYA 2N8RA 4L7AA 2MZHA 1B3DA 3G5CA 2CKIA 4XM6A 3NX7A 2OXUA 2E3XA 1HFCA 4XM7A 1D8MA 1GKDA 1IAGA 4GR0A 1I76A 4GWNA 4FXYP 5BOYA 4DD8A 2DDFA 2JSDA 4WZVA 1UTZA 1IAEA 1OS2A 1MMBA 3DTEA 3LIKA 3LIRA 4A3WA 1CK7A 4H2EA 1SMPA 2OW0A 4WKEA 3DNGA 1K7IA 3DWBA 1EAKA 1KBCA 1Z3JA 5JMYA 3RTSA 3B8ZA 4CTHA 1S4BP 2J0TA 1OM7A 1QIBA 2TCLA 1JANA 1JAPA 1GXDA 2X3CA 4JIJA 1PWQA 3KEJA 1ASTA 2CLTA 1Q3AA 1CIZA 3OHLA 5D1SA 1MMRA 1SATA 4H30A 2OY4A 5BPAA 4ILWD 1PWPA 1HV5A 1XFYA 1C3IA 2JNPA 3LKAA 3SHIA 4AYKA 2OW1A 1JKYA 2DW2A 5I0LA 1ZS0A 1BKCI 3AYKA 2MZIA 5B5PA 5I43A 5I3MA 2OW9A 1BKCA 2K2GA 1R1JA 2POJA 4PKSA 3F16A 4XBHA 1BQQM 3LJTA 2O3EA 3TSKA 3F17A 5I12A 3LJZA 1XUCA 1RM8A 1JAQA 4H82A 1UEAA 2WO8A 2X3BA 3O2XA 3EDIA 3LGPA 2DDYA 1KAPP 3KMCA 5D1TA 456CA 1QICA 1SLMA 1SRPA 1HFSA 1JJ9A 2MLSA
chains in the Genus database with same CATH topology
1SU3A 2AYKA 3EDGA 4H1QA 5L7FA 3V96B 1YQYA 3VI1A 2D1OA 3ZVSA 1FBLA 1JIZA 4XM8A 3TVCA 1G4KA 3VTGA 3N2VA 1O0QA 1ZXVA 4I03A 1G05A 1QUAA 2Z2DA 3DPFA 4HX3A 2XS3A 3B2ZA 4L19A 1HY7A 4L6TA 1D8FA 1I1IP 1MMPA 1CGFA 3N2UA 3KEKA 3LILA 3UVCA 1R1HA 1G9KA 4ON1A 2RJQA 1PWUA 3LJGA 4JP4A 1D5JA 3WV2A 1KUGA 5CUHA 3DSLA 1D7XA 4PKWA 1GO8P 4XCTA 2JT6A 1CAQA 1XFUA 4R3VA 1GE5A 1QJJA 4H76A 3HY7A 2MZEA 2I47A 3HDAP 5D7WA 1GE7A 5BOTA 3DTIA 3LQ0A 4PKUA 4GF1A 3P24A 1YCMA 1EUBA 1HOVA 1JK3A 2OVXA 4JPAA 4GR3A 3KHIA 2D1NA 3KECA 2K9CA 1R55A 2JIHA 1Y93A 2YIGA 4L63A 4PKTA 4HMAA 2OI0A 4A7BA 2FV9A 5D3CA 1B8YA 1MMQA 3TS4A 2WOAA 4I35A 1G12A 1C8TA 1RMZA 4IUWA 1XFVA 2YB9A 3HBUP 3EDHA 3LQBA 3O64A 1IACA 3Q2HA 3HBVP 1BIWA 2W0DA 3DPEA 3LUNA 3MA2A 1XURA 1H71P 830CA 1IAAA 1GO7P 1ZXCA 5L79A 4WF6A 2DW1A 1UMSA 3F18A 1USNA 3LUMA 3LMCA 1QIAA 3ZUKA 1IADA 1PWVA 1OM8A 4J4MA 1BUDA 1XFWA 4JA1A 3GBOA 1AYKA 4WK7A 3U1RA 1CQRA 2HU6A 4GQLA 1CGLA 4IN9A 1C7KA 3K7NA 4FVLA 2YUFA 966CA 2W12A 4G9LA 2AIGP 2W13A 3WV1A 2MLRA 4JQGA 3L0TA 3ZXHA 1ROSA 1CXVA 4H84A 3B92A 1KUFA 1AF0A 2ERQA 4IJOA 1YP1A 2X7MA 1BQOA 1KUHA 3DTKA 3G42A 4H49A 4GWMA 1UTTA 5H8XA 3EDZA 1Y8JA 2KRJA 1EB6A 1YOUA 1ATLA 3LE9A 2Y6DA 3ELMA 4GUYA 4ZR5A 2J83A 3I7IA 5I4OA 2OVZA 1J7NA 3HB2P 1KUIA 1AKLA 4AUOA 2WO9A 1XFXA 1BSWA 3EHXA 3KMEA 2SRTA 1BUVM 2OZRA 2FV5A 3LK8A 1QJIA 4WKIA 4AXQA 2EROA 3HY9A 2X3AA 1PWWA 1G49A 1L6JA 4DF9A 5D2BA 1O0TA 4PKQA 5B5OA 1JAOA 1DTHA 4FU4A 1BM6A 1K7QA 1HTDA 3K7LA 2OY2A 4PKVA 1SLNA 2USNA 1R1IA 5I2ZA 1XUDA 3RTTA 2L0RA 2E2DA 4G0DA 2XS4A 3F19A 1BKCE 5CZMA 1OMJA 3F15A 4FXQA 1A85A 1OO9A 3HYGA 3BA0A 1GE6A 3E8RA 3HDBA 3CKIA 4DPEA 3Q2GA 4H3XA 3AIGA 2OXWA 4DV8A 1DMTA 1UMTA 2RJPA 2OW2A 1IABA 5CXAA 4Q1LA 2W15A 3OHOA 2QPJA 5D1UA 1KUKA 3KRYA 3LEAA 1FLSA 2Y6CA 1A86A 1K7GA 1OM6A 3F1AA 1GKCA 1ZVXA 1I73A 3KWVC 4GR8A 1ZTQA 1MNCA 3I7GA 4QKZA 3WV3A 1JIWP 1XFZA 2O36A 1WNIA 2OXZA 2JT5A 1R54A 2PJTA 1ND1A 1JH1A 5LABA 2DW0A 1ZP5A 3DL1A 1FM1A 1CGEA 3EWJA 3USNA 1Y0VA 2A8HA 3L0VA 2W14A 4EFSA 4AIGA 2ERPA 3P1VA 2V4BA 4PKRA 3TT4A 1OS9A 3AYUA 1BZSA 3EHYA 2N8RA 4L7AA 2MZHA 1B3DA 3G5CA 2CKIA 4XM6A 3NX7A 2OXUA 2E3XA 1HFCA 4XM7A 1D8MA 1GKDA 1IAGA 4GR0A 1I76A 4GWNA 4FXYP 5BOYA 4DD8A 2DDFA 2JSDA 4WZVA 1UTZA 1IAEA 1OS2A 1MMBA 3DTEA 3LIKA 3LIRA 4A3WA 1CK7A 4H2EA 1SMPA 2OW0A 4WKEA 3DNGA 1K7IA 3DWBA 1EAKA 1KBCA 1Z3JA 5JMYA 3RTSA 3B8ZA 4CTHA 1S4BP 2J0TA 1OM7A 1QIBA 2TCLA 1JANA 1JAPA 1GXDA 2X3CA 4JIJA 1PWQA 3KEJA 1ASTA 2CLTA 1Q3AA 1CIZA 3OHLA 5D1SA 1MMRA 1SATA 4H30A 2OY4A 5BPAA 4ILWD 1PWPA 1HV5A 1XFYA 1C3IA 2JNPA 3LKAA 3SHIA 4AYKA 2OW1A 1JKYA 2DW2A 5I0LA 1ZS0A 1BKCI 3AYKA 2MZIA 5B5PA 5I43A 5I3MA 2OW9A 1BKCA 2K2GA 1R1JA 2POJA 4PKSA 3F16A 4XBHA 1BQQM 3LJTA 2O3EA 3TSKA 3F17A 5I12A 3LJZA 1XUCA 1RM8A 1JAQA 4H82A 1UEAA 2WO8A 2X3BA 3O2XA 3EDIA 3LGPA 2DDYA 1KAPP 3KMCA 5D1TA 456CA 1QICA 1SLMA 1SRPA 1HFSA 1JJ9A 2MLSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SU3 A;  2AYK A;  3EDG A;  4H1Q A;  5L7F A;  3V96 B;  1YQY A;  3VI1 A;  2D1O A;  3ZVS A;  1FBL A;  1JIZ A;  4XM8 A;  3TVC A;  1G4K A;  3VTG A;  3N2V A;  1O0Q A;  1ZXV A;  4I03 A;  1G05 A;  1QUA A;  2Z2D A;  3DPF A;  4HX3 A;  2XS3 A;  3B2Z A;  4L19 A;  1HY7 A;  4L6T A;  1D8F A;  1I1I P;  1MMP A;  1CGF A;  3N2U A;  3KEK A;  3LIL A;  3UVC A;  1R1H A;  1G9K A;  4ON1 A;  2RJQ A;  1PWU A;  3LJG A;  4JP4 A;  1D5J A;  3WV2 A;  1KUG A;  5CUH A;  3DSL A;  1D7X A;  4PKW A;  1GO8 P;  4XCT A;  2JT6 A;  1CAQ A;  1XFU A;  4R3V A;  1GE5 A;  1QJJ A;  4H76 A;  3HY7 A;  2MZE A;  2I47 A;  3HDA P;  5D7W A;  1GE7 A;  5BOT A;  3LQ0 A;  4PKU A;  4GF1 A;  3P24 A;  1YCM A;  1EUB A;  1HOV A;  1JK3 A;  2OVX A;  4JPA A;  4GR3 A;  3KHI A;  2D1N A;  3KEC A;  2K9C A;  1R55 A;  2JIH A;  1Y93 A;  2YIG A;  4L63 A;  4PKT A;  4HMA A;  2OI0 A;  4A7B A;  2FV9 A;  5D3C A;  1B8Y A;  1MMQ A;  3TS4 A;  2WOA A;  4I35 A;  1G12 A;  1C8T A;  1RMZ A;  4IUW A;  1XFV A;  2YB9 A;  3HBU P;  3EDH A;  3LQB A;  3O64 A;  1IAC A;  3Q2H A;  3HBV P;  1BIW A;  2W0D A;  3DPE A;  3LUN A;  3MA2 A;  1XUR A;  1H71 P;  830C A;  1IAA A;  1GO7 P;  1ZXC A;  5L79 A;  4WF6 A;  2DW1 A;  1UMS A;  3F18 A;  1USN A;  3LUM A;  3LMC A;  1QIA A;  3ZUK A;  1IAD A;  1PWV A;  1OM8 A;  4J4M A;  1BUD A;  1XFW A;  4JA1 A;  3GBO A;  1AYK A;  4WK7 A;  3U1R A;  1CQR A;  2HU6 A;  4GQL A;  1CGL A;  4IN9 A;  1C7K A;  3K7N A;  4FVL A;  966C A;  2W12 A;  4G9L A;  2AIG P;  2W13 A;  3WV1 A;  2MLR A;  4JQG A;  3L0T A;  3ZXH A;  1ROS A;  1CXV A;  4H84 A;  3B92 A;  1KUF A;  1AF0 A;  2ERQ A;  4IJO A;  1YP1 A;  2X7M A;  1BQO A;  1KUH A;  3G42 A;  4H49 A;  4GWM A;  1UTT A;  5H8X A;  3EDZ A;  1Y8J A;  2KRJ A;  1EB6 A;  1YOU A;  1ATL A;  3LE9 A;  2Y6D A;  3ELM A;  4GUY A;  4ZR5 A;  2J83 A;  3I7I A;  5I4O A;  2OVZ A;  1J7N A;  3HB2 P;  1KUI A;  1AKL A;  4AUO A;  2WO9 A;  1XFX A;  1BSW A;  3EHX A;  3KME A;  2SRT A;  1BUV M;  2OZR A;  2FV5 A;  3LK8 A;  1QJI A;  4WKI A;  4AXQ A;  2ERO A;  3HY9 A;  2X3A A;  1PWW A;  1G49 A;  1L6J A;  4DF9 A;  5D2B A;  1O0T A;  4PKQ A;  5B5O A;  1JAO A;  1DTH A;  4FU4 A;  1BM6 A;  1K7Q A;  1HTD A;  3K7L A;  2OY2 A;  4PKV A;  1SLN A;  2USN A;  1R1I A;  5I2Z A;  1XUD A;  3RTT A;  2L0R A;  2E2D A;  4G0D A;  2XS4 A;  3F19 A;  1BKC E;  5CZM A;  1OMJ A;  3F15 A;  4FXQ A;  1A85 A;  1OO9 A;  3HYG A;  3BA0 A;  1GE6 A;  3E8R A;  3HDB A;  3CKI A;  4DPE A;  3Q2G A;  4H3X A;  3AIG A;  2OXW A;  4DV8 A;  1DMT A;  1UMT A;  2RJP A;  2OW2 A;  1IAB A;  5CXA A;  4Q1L A;  2W15 A;  3OHO A;  2QPJ A;  5D1U A;  1KUK A;  3KRY A;  3LEA A;  1FLS A;  2Y6C A;  1A86 A;  1K7G A;  1OM6 A;  3F1A A;  1GKC A;  1ZVX A;  1I73 A;  3KWV C;  4GR8 A;  1ZTQ A;  1MNC A;  3I7G A;  4QKZ A;  3WV3 A;  1JIW P;  1XFZ A;  2O36 A;  1WNI A;  2OXZ A;  2JT5 A;  1R54 A;  2PJT A;  1ND1 A;  1JH1 A;  5LAB A;  2DW0 A;  1ZP5 A;  3DL1 A;  1FM1 A;  1CGE A;  3EWJ A;  3USN A;  1Y0V A;  2A8H A;  3L0V A;  2W14 A;  4EFS A;  4AIG A;  2ERP A;  3P1V A;  2V4B A;  4PKR A;  3TT4 A;  1OS9 A;  3AYU A;  1BZS A;  3EHY A;  2N8R A;  2MZH A;  1B3D A;  3G5C A;  2CKI A;  4XM6 A;  3NX7 A;  2OXU A;  2E3X A;  1HFC A;  4XM7 A;  1D8M A;  1GKD A;  1IAG A;  4GR0 A;  1I76 A;  4GWN A;  4FXY P;  5BOY A;  4DD8 A;  2DDF A;  2JSD A;  4WZV A;  1UTZ A;  1IAE A;  1OS2 A;  1MMB A;  3LIK A;  3LIR A;  4A3W A;  1CK7 A;  4H2E A;  1SMP A;  2OW0 A;  4WKE A;  3DNG A;  1K7I A;  3DWB A;  1EAK A;  1KBC A;  1Z3J A;  5JMY A;  3RTS A;  3B8Z A;  4CTH A;  1S4B P;  2J0T A;  1OM7 A;  1QIB A;  2TCL A;  1JAN A;  1JAP A;  1GXD A;  2X3C A;  4JIJ A;  1PWQ A;  3KEJ A;  1AST A;  2CLT A;  1Q3A A;  1CIZ A;  3OHL A;  5D1S A;  1MMR A;  1SAT A;  4H30 A;  2OY4 A;  5BPA A;  4ILW D;  1PWP A;  1HV5 A;  1XFY A;  1C3I A;  2JNP A;  3LKA A;  3SHI A;  4AYK A;  2OW1 A;  1JKY A;  2DW2 A;  5I0L A;  1ZS0 A;  1BKC I;  3AYK A;  2MZI A;  5B5P A;  5I43 A;  5I3M A;  2OW9 A;  1BKC A;  2K2G A;  1R1J A;  2POJ A;  4PKS A;  3F16 A;  4XBH A;  1BQQ M;  3LJT A;  2O3E A;  3TSK A;  3F17 A;  5I12 A;  3LJZ A;  1XUC A;  1RM8 A;  1JAQ A;  4H82 A;  1UEA A;  2WO8 A;  2X3B A;  3O2X A;  3EDI A;  3LGP A;  2DDY A;  1KAP P;  3KMC A;  5D1T A;  456C A;  1QIC A;  1SLM A;  1SRP A;  1HFS A;  1JJ9 A;  2MLS A; 
#chains in the Genus database with same CATH topology
 1SU3 A;  2AYK A;  3EDG A;  4H1Q A;  5L7F A;  3V96 B;  1YQY A;  3VI1 A;  2D1O A;  3ZVS A;  1FBL A;  1JIZ A;  4XM8 A;  3TVC A;  1G4K A;  3VTG A;  3N2V A;  1O0Q A;  1ZXV A;  4I03 A;  1G05 A;  1QUA A;  2Z2D A;  3DPF A;  4HX3 A;  2XS3 A;  3B2Z A;  4L19 A;  1HY7 A;  4L6T A;  1D8F A;  1I1I P;  1MMP A;  1CGF A;  3N2U A;  3KEK A;  3LIL A;  3UVC A;  1R1H A;  1G9K A;  4ON1 A;  2RJQ A;  1PWU A;  3LJG A;  4JP4 A;  1D5J A;  3WV2 A;  1KUG A;  5CUH A;  3DSL A;  1D7X A;  4PKW A;  1GO8 P;  4XCT A;  2JT6 A;  1CAQ A;  1XFU A;  4R3V A;  1GE5 A;  1QJJ A;  4H76 A;  3HY7 A;  2MZE A;  2I47 A;  3HDA P;  5D7W A;  1GE7 A;  5BOT A;  3DTI A;  3LQ0 A;  4PKU A;  4GF1 A;  3P24 A;  1YCM A;  1EUB A;  1HOV A;  1JK3 A;  2OVX A;  4JPA A;  4GR3 A;  3KHI A;  2D1N A;  3KEC A;  2K9C A;  1R55 A;  2JIH A;  1Y93 A;  2YIG A;  4L63 A;  4PKT A;  4HMA A;  2OI0 A;  4A7B A;  2FV9 A;  5D3C A;  1B8Y A;  1MMQ A;  3TS4 A;  2WOA A;  4I35 A;  1G12 A;  1C8T A;  1RMZ A;  4IUW A;  1XFV A;  2YB9 A;  3HBU P;  3EDH A;  3LQB A;  3O64 A;  1XAX A;  1IAC A;  3Q2H A;  3HBV P;  1BIW A;  2W0D A;  3DPE A;  3LUN A;  3MA2 A;  1XUR A;  1H71 P;  830C A;  1IAA A;  1GO7 P;  1ZXC A;  5L79 A;  4WF6 A;  2DW1 A;  1UMS A;  3F18 A;  1USN A;  3LUM A;  3LMC A;  1QIA A;  3ZUK A;  1IAD A;  1PWV A;  1OM8 A;  4J4M A;  1BUD A;  1XFW A;  4JA1 A;  3GBO A;  1AYK A;  4WK7 A;  3U1R A;  1CQR A;  2HU6 A;  4GQL A;  1CGL A;  4IN9 A;  1C7K A;  3K7N A;  4FVL A;  2YUF A;  966C A;  2W12 A;  4G9L A;  2AIG P;  2W13 A;  3WV1 A;  2MLR A;  4JQG A;  3L0T A;  3ZXH A;  1ROS A;  1CXV A;  4H84 A;  3B92 A;  1KUF A;  1AF0 A;  2ERQ A;  4IJO A;  1YP1 A;  2X7M A;  1BQO A;  1KUH A;  3DTK A;  3G42 A;  4H49 A;  4GWM A;  1UTT A;  5H8X A;  3EDZ A;  1Y8J A;  2KRJ A;  1EB6 A;  1YOU A;  1ATL A;  3LE9 A;  2Y6D A;  3ELM A;  4GUY A;  4ZR5 A;  2J83 A;  3I7I A;  5I4O A;  2OVZ A;  1J7N A;  3HB2 P;  1KUI A;  1AKL A;  4AUO A;  2WO9 A;  1XFX A;  1BSW A;  1XM5 A;  3EHX A;  3KME A;  2SRT A;  1BUV M;  2OZR A;  2FV5 A;  3LK8 A;  1QJI A;  4WKI A;  4AXQ A;  2ERO A;  3HY9 A;  2X3A A;  1PWW A;  1G49 A;  1L6J A;  4DF9 A;  5D2B A;  1O0T A;  4PKQ A;  5B5O A;  1JAO A;  1DTH A;  4FU4 A;  1BM6 A;  1K7Q A;  1HTD A;  3K7L A;  2OY2 A;  4PKV A;  1SLN A;  2USN A;  1R1I A;  5I2Z A;  1XUD A;  3RTT A;  2L0R A;  2E2D A;  4G0D A;  2XS4 A;  3F19 A;  1BKC E;  5CZM A;  1OMJ A;  3F15 A;  4FXQ A;  1A85 A;  1OO9 A;  3HYG A;  3BA0 A;  1GE6 A;  3E8R A;  3HDB A;  3CKI A;  4DPE A;  3Q2G A;  4H3X A;  3AIG A;  2OXW A;  4DV8 A;  1DMT A;  1UMT A;  2RJP A;  2OW2 A;  1IAB A;  5CXA A;  4Q1L A;  2W15 A;  3OHO A;  2QPJ A;  5D1U A;  1KUK A;  3KRY A;  3LEA A;  1FLS A;  2Y6C A;  1A86 A;  1K7G A;  1OM6 A;  3F1A A;  1GKC A;  1ZVX A;  1I73 A;  3KWV C;  4GR8 A;  1ZTQ A;  1MNC A;  3I7G A;  4QKZ A;  3WV3 A;  1JIW P;  1XFZ A;  2O36 A;  1WNI A;  2OXZ A;  2JT5 A;  1R54 A;  2PJT A;  1ND1 A;  1JH1 A;  5LAB A;  2DW0 A;  1ZP5 A;  3DL1 A;  1OZ9 A;  1FM1 A;  1CGE A;  3EWJ A;  3USN A;  1Y0V A;  2A8H A;  3L0V A;  1TVI A;  2W14 A;  4EFS A;  4AIG A;  2ERP A;  3P1V A;  2V4B A;  4PKR A;  3TT4 A;  1OS9 A;  3AYU A;  1BZS A;  3EHY A;  2N8R A;  4L7A A;  2MZH A;  1B3D A;  3G5C A;  2CKI A;  4XM6 A;  3NX7 A;  2OXU A;  2E3X A;  1HFC A;  4XM7 A;  1D8M A;  1GKD A;  1IAG A;  4GR0 A;  1I76 A;  4GWN A;  4FXY P;  5BOY A;  4DD8 A;  2DDF A;  2JSD A;  4WZV A;  1UTZ A;  1IAE A;  1OS2 A;  1MMB A;  3DTE A;  3LIK A;  3LIR A;  4A3W A;  1CK7 A;  4H2E A;  1SMP A;  2OW0 A;  4WKE A;  3DNG A;  1K7I A;  3DWB A;  1EAK A;  1KBC A;  1Z3J A;  5JMY A;  3RTS A;  3B8Z A;  4CTH A;  1S4B P;  2J0T A;  1OM7 A;  1QIB A;  2TCL A;  1JAN A;  1JAP A;  1GXD A;  2X3C A;  4JIJ A;  1PWQ A;  3KEJ A;  1AST A;  2CLT A;  1Q3A A;  1CIZ A;  3OHL A;  5D1S A;  1MMR A;  1SAT A;  4H30 A;  2OY4 A;  5BPA A;  4ILW D;  1PWP A;  1HV5 A;  1XFY A;  1C3I A;  2JNP A;  3LKA A;  3SHI A;  4AYK A;  2OW1 A;  1JKY A;  2DW2 A;  5I0L A;  1ZS0 A;  1BKC I;  3AYK A;  2MZI A;  5B5P A;  5I43 A;  5I3M A;  2OW9 A;  1BKC A;  2K2G A;  1R1J A;  2POJ A;  4PKS A;  3F16 A;  4XBH A;  1BQQ M;  3LJT A;  2O3E A;  3TSK A;  3F17 A;  5I12 A;  3LJZ A;  1XUC A;  1RM8 A;  1JAQ A;  4H82 A;  1UEA A;  2WO8 A;  2X3B A;  3O2X A;  3EDI A;  3LGP A;  2DDY A;  1KAP P;  3KMC A;  5D1T A;  456C A;  1QIC A;  1SLM A;  1SRP A;  1HFS A;  1JJ9 A;  2MLS A; 
#chains in the Genus database with same CATH homology
 1SU3 A;  2AYK A;  3EDG A;  4H1Q A;  5L7F A;  3V96 B;  1YQY A;  3VI1 A;  2D1O A;  3ZVS A;  1FBL A;  1JIZ A;  4XM8 A;  3TVC A;  1G4K A;  3VTG A;  3N2V A;  1O0Q A;  1ZXV A;  4I03 A;  1G05 A;  1QUA A;  2Z2D A;  3DPF A;  4HX3 A;  2XS3 A;  3B2Z A;  4L19 A;  1HY7 A;  4L6T A;  1D8F A;  1I1I P;  1MMP A;  1CGF A;  3N2U A;  3KEK A;  3LIL A;  3UVC A;  1R1H A;  1G9K A;  4ON1 A;  2RJQ A;  1PWU A;  3LJG A;  4JP4 A;  1D5J A;  3WV2 A;  1KUG A;  5CUH A;  3DSL A;  1D7X A;  4PKW A;  1GO8 P;  4XCT A;  2JT6 A;  1CAQ A;  1XFU A;  4R3V A;  1GE5 A;  1QJJ A;  4H76 A;  3HY7 A;  2MZE A;  2I47 A;  3HDA P;  5D7W A;  1GE7 A;  5BOT A;  3DTI A;  3LQ0 A;  4PKU A;  4GF1 A;  3P24 A;  1YCM A;  1EUB A;  1HOV A;  1JK3 A;  2OVX A;  4JPA A;  4GR3 A;  3KHI A;  2D1N A;  3KEC A;  2K9C A;  1R55 A;  2JIH A;  1Y93 A;  2YIG A;  4L63 A;  4PKT A;  4HMA A;  2OI0 A;  4A7B A;  2FV9 A;  5D3C A;  1B8Y A;  1MMQ A;  3TS4 A;  2WOA A;  4I35 A;  1G12 A;  1C8T A;  1RMZ A;  4IUW A;  1XFV A;  2YB9 A;  3HBU P;  3EDH A;  3LQB A;  3O64 A;  1IAC A;  3Q2H A;  3HBV P;  1BIW A;  2W0D A;  3DPE A;  3LUN A;  3MA2 A;  1XUR A;  1H71 P;  830C A;  1IAA A;  1GO7 P;  1ZXC A;  5L79 A;  4WF6 A;  2DW1 A;  1UMS A;  3F18 A;  1USN A;  3LUM A;  3LMC A;  1QIA A;  3ZUK A;  1IAD A;  1PWV A;  1OM8 A;  4J4M A;  1BUD A;  1XFW A;  4JA1 A;  3GBO A;  1AYK A;  4WK7 A;  3U1R A;  1CQR A;  2HU6 A;  4GQL A;  1CGL A;  4IN9 A;  1C7K A;  3K7N A;  4FVL A;  2YUF A;  966C A;  2W12 A;  4G9L A;  2AIG P;  2W13 A;  3WV1 A;  2MLR A;  4JQG A;  3L0T A;  3ZXH A;  1ROS A;  1CXV A;  4H84 A;  3B92 A;  1KUF A;  1AF0 A;  2ERQ A;  4IJO A;  1YP1 A;  2X7M A;  1BQO A;  1KUH A;  3DTK A;  3G42 A;  4H49 A;  4GWM A;  1UTT A;  5H8X A;  3EDZ A;  1Y8J A;  2KRJ A;  1EB6 A;  1YOU A;  1ATL A;  3LE9 A;  2Y6D A;  3ELM A;  4GUY A;  4ZR5 A;  2J83 A;  3I7I A;  5I4O A;  2OVZ A;  1J7N A;  3HB2 P;  1KUI A;  1AKL A;  4AUO A;  2WO9 A;  1XFX A;  1BSW A;  3EHX A;  3KME A;  2SRT A;  1BUV M;  2OZR A;  2FV5 A;  3LK8 A;  1QJI A;  4WKI A;  4AXQ A;  2ERO A;  3HY9 A;  2X3A A;  1PWW A;  1G49 A;  1L6J A;  4DF9 A;  5D2B A;  1O0T A;  4PKQ A;  5B5O A;  1JAO A;  1DTH A;  4FU4 A;  1BM6 A;  1K7Q A;  1HTD A;  3K7L A;  2OY2 A;  4PKV A;  1SLN A;  2USN A;  1R1I A;  5I2Z A;  1XUD A;  3RTT A;  2L0R A;  2E2D A;  4G0D A;  2XS4 A;  3F19 A;  1BKC E;  5CZM A;  1OMJ A;  3F15 A;  4FXQ A;  1A85 A;  1OO9 A;  3HYG A;  3BA0 A;  1GE6 A;  3E8R A;  3HDB A;  3CKI A;  4DPE A;  3Q2G A;  4H3X A;  3AIG A;  2OXW A;  4DV8 A;  1DMT A;  1UMT A;  2RJP A;  2OW2 A;  1IAB A;  5CXA A;  4Q1L A;  2W15 A;  3OHO A;  2QPJ A;  5D1U A;  1KUK A;  3KRY A;  3LEA A;  1FLS A;  2Y6C A;  1A86 A;  1K7G A;  1OM6 A;  3F1A A;  1GKC A;  1ZVX A;  1I73 A;  3KWV C;  4GR8 A;  1ZTQ A;  1MNC A;  3I7G A;  4QKZ A;  3WV3 A;  1JIW P;  1XFZ A;  2O36 A;  1WNI A;  2OXZ A;  2JT5 A;  1R54 A;  2PJT A;  1ND1 A;  1JH1 A;  5LAB A;  2DW0 A;  1ZP5 A;  3DL1 A;  1FM1 A;  1CGE A;  3EWJ A;  3USN A;  1Y0V A;  2A8H A;  3L0V A;  2W14 A;  4EFS A;  4AIG A;  2ERP A;  3P1V A;  2V4B A;  4PKR A;  3TT4 A;  1OS9 A;  3AYU A;  1BZS A;  3EHY A;  2N8R A;  4L7A A;  2MZH A;  1B3D A;  3G5C A;  2CKI A;  4XM6 A;  3NX7 A;  2OXU A;  2E3X A;  1HFC A;  4XM7 A;  1D8M A;  1GKD A;  1IAG A;  4GR0 A;  1I76 A;  4GWN A;  4FXY P;  5BOY A;  4DD8 A;  2DDF A;  2JSD A;  4WZV A;  1UTZ A;  1IAE A;  1OS2 A;  1MMB A;  3DTE A;  3LIK A;  3LIR A;  4A3W A;  1CK7 A;  4H2E A;  1SMP A;  2OW0 A;  4WKE A;  3DNG A;  1K7I A;  3DWB A;  1EAK A;  1KBC A;  1Z3J A;  5JMY A;  3RTS A;  3B8Z A;  4CTH A;  1S4B P;  2J0T A;  1OM7 A;  1QIB A;  2TCL A;  1JAN A;  1JAP A;  1GXD A;  2X3C A;  4JIJ A;  1PWQ A;  3KEJ A;  1AST A;  2CLT A;  1Q3A A;  1CIZ A;  3OHL A;  5D1S A;  1MMR A;  1SAT A;  4H30 A;  2OY4 A;  5BPA A;  4ILW D;  1PWP A;  1HV5 A;  1XFY A;  1C3I A;  2JNP A;  3LKA A;  3SHI A;  4AYK A;  2OW1 A;  1JKY A;  2DW2 A;  5I0L A;  1ZS0 A;  1BKC I;  3AYK A;  2MZI A;  5B5P A;  5I43 A;  5I3M A;  2OW9 A;  1BKC A;  2K2G A;  1R1J A;  2POJ A;  4PKS A;  3F16 A;  4XBH A;  1BQQ M;  3LJT A;  2O3E A;  3TSK A;  3F17 A;  5I12 A;  3LJZ A;  1XUC A;  1RM8 A;  1JAQ A;  4H82 A;  1UEA A;  2WO8 A;  2X3B A;  3O2X A;  3EDI A;  3LGP A;  2DDY A;  1KAP P;  3KMC A;  5D1T A;  456C A;  1QIC A;  1SLM A;  1SRP A;  1HFS A;  1JJ9 A;  2MLS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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