2ZJPS

Thiopeptide antibiotic nosiheptide bound to the large ribosomal subunit of deinococcus radiodurans
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
175
structure length
175
Chain Sequence
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords 50S RIBOSOMAL PROTEIN L33
total genus 15
structure length 175
sequence length 175
ec nomenclature
pdb deposition date 2008-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 2zjpS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 2zjpS02
1QTQA 2ZJQS 5GAHW 3DLLS 4JXXA 5HL7S 1D6KA 4WFBS 4WFAS 2RE8A 4WF9S 5DM7S 1GTSA 2RD2A 5JVHS 4IOCS 1DFUP 1QRSA 5JVGS 3J7ZV 1QRUA 5GAEW 4JYZA 1B75A 4WFNS 4P2BA 5DM6S 2ZJPS 5BNZA 2ZJRS 1O0CA 4UY88 1NYLA 2HZ7A 3PIOS 4IOAS 1FEUA 4U67S 1O0BA 1EXDA 1GTRA 5GAGW 5GADW 4H3SA 1ZJWA 4JXZA 5IZNA 1EUYA 4WCES 1QRTA 3CF5S 3PIPS 3AIIA 1EUQA 4IO9S
chains in the Genus database with same CATH superfamily
2PJJA 2Y0SD 5GAHW 2PNWA 5HL7S 4WFBS 4WFAS 3FKIC 4C3JC 4NOIA 5HQHA 1I6VA 4L69A 1GTSA 2RD2A 3GTJC 3X1LB 3H3VD 4IOCS 1DFUP 5IYBC 3S17C 3I4NC 1YNNA 5JVGS 1HQMA 1VHYA 4LK1A 4JYZA 5C44C 4OIRA 4V194 4YFKA 2E2HC 3PO3C 4QIWD 4Y7NC 3GTGC 5BNZA 3PO2C 3PIOS 4E8BA 2NVTC 4A3DC 1I6HC 1FEUA 3HOXC 4A3JC 2JA7C 2R7ZC 1TWGC 4LJZA 2PI8A 4XSXA 2B63C 3GTLC 3M3YC 3LYWA 4MQ9A 4C3HC 4KMUA 5IZNA 3M4OC 3S1MC 2BE5A 4A3FC 3HOUC 3CF5S 3PIPS 3S14C 4ZH4A 4G7OA 2EGVA 3RZDC 4G7HA 4G7ZA 3GTKC 2VUMC 5C4JC 5TMFA 2E2IC 4JK1A 4Q4ZA 4J3CA 4WF9S 2EGWA 5IP9C 4Y52C 5TMCA 4OINA 4A3IC 1BDFA 3H0GC 5GAEW 5IYDC 1B75A 2NVXC 4X6AC 3S15C 4A3EC 4P2BA 3CZBA 5DM6S 4YFNA 5D4DA 4UY88 3HKZD 2HZ7A 2CX8A 1TWHC 4U67S 1V6ZA 2A6HA 3GTMC 3GTOC 4A3MC 1GTRA 3GTPC 5GAGW 4H3SA 2PICA 4JXZA 3W2WB 1SFOC 1QRTA 4BXXC 3S2DC 1IW7A 4GZYA 4OIPA 1VHKA 4MEYA 1QTQA 1TWCC 2ZJQS 3WODA 4XLNA 1SMYA 3DXJA 1D6KA 2G5DA 4BY7C 4A3LC 1Y1WC 4A3BC 2RE8A 4MEXA 2G6GA 5IYCC 2L5NA 4QJVA 1I3QC 3S1RC 3J7ZV 4C2MC 2NVQC 5IP7C 3S2HC 1TWAC 5C4XC 4WFNS 1R9TC 1TWFC 2JA8C 2ZJPS 1O0CA 3GTQC 2R92C 2NVYC 2A68A 2AE0X 2O5JA 2Z0YA 3S1QC 1O0BA 4OIQA 4A93C 4LK0A 4C3IC 1UDXA 4WCES 2WAQD 2PA8D 1Y1VC 4KN4A 1EUQA 3HOYC 5C3EC 4YG2A 4BY1C 2O5IA 3DLLS 4JXXA 4LLGA 3S1NC 3HOWC 3KW2A 3K7AC 4A3KC 2E2JC 2PPBA 1WCMC 5DM7S 2YU9C 2NWAA 5JVHS 2CW0A 2A6EA 4OIOA 2KPUA 4YFXA 1QRSA 2GAEA 1K83C 3EQLA 1QRUA 1Z85A 4A3GC 3HOZC 5FLMC 2L3UA 4XLPA 4Q5SA 2ZJRS 1NYLA 4IOAS 2R93C 2KQ1A 2PMZD 1EXDA 1YNJA 3CQZC 4XSZA 1NXZA 2A69A 3RZOC 5GADW 4BBSC 2WB1D 2KXYA 4A3CC 3HOVC 1ZJWA 2JA5C 3W2VB 1EUYA 3I4MC 4AYBD 4H4KA 1I50C 1ZYRA 3AIIA 3S16C 2JA6C 4KN7A 4BBRC 4IO9S
chains in the Genus database with same CATH topology
1QTQA 2ZJQS 5GAHW 3DLLS 4JXXA 5HL7S 1D6KA 4WFBS 4WFAS 2RE8A 4WF9S 5DM7S 1GTSA 2RD2A 5JVHS 3X1LB 4IOCS 1DFUP 1QRSA 5JVGS 3J7ZV 1QRUA 5GAEW 4JYZA 1B75A 4V194 4WFNS 4P2BA 5DM6S 2ZJPS 5BNZA 2ZJRS 1O0CA 4UY88 1NYLA 2HZ7A 3PIOS 4IOAS 1FEUA 4U67S 1O0BA 1EXDA 1GTRA 5GAGW 5GADW 4H3SA 1ZJWA 4JXZA 3W2WB 1UDXA 3W2VB 5IZNA 1EUYA 4WCES 1QRTA 3CF5S 3PIPS 4H4KA 3AIIA 1EUQA 4IO9S
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QTQ A;  2ZJQ S;  5GAH W;  3DLL S;  4JXX A;  5HL7 S;  1D6K A;  4WFB S;  4WFA S;  2RE8 A;  4WF9 S;  5DM7 S;  1GTS A;  2RD2 A;  5JVH S;  4IOC S;  1DFU P;  1QRS A;  5JVG S;  3J7Z V;  1QRU A;  5GAE W;  4JYZ A;  1B75 A;  4WFN S;  4P2B A;  5DM6 S;  2ZJP S;  5BNZ A;  2ZJR S;  1O0C A;  4UY8 8;  1NYL A;  2HZ7 A;  3PIO S;  4IOA S;  1FEU A;  4U67 S;  1O0B A;  1EXD A;  1GTR A;  5GAG W;  5GAD W;  4H3S A;  1ZJW A;  4JXZ A;  5IZN A;  1EUY A;  4WCE S;  1QRT A;  3CF5 S;  3PIP S;  3AII A;  1EUQ A;  4IO9 S; 
#chains in the Genus database with same CATH topology
 2PJJ A;  2Y0S D;  5GAH W;  2PNW A;  5HL7 S;  4WFB S;  4WFA S;  3FKI C;  4C3J C;  4NOI A;  5HQH A;  1I6V A;  4L69 A;  1GTS A;  2RD2 A;  3GTJ C;  3X1L B;  3H3V D;  4IOC S;  1DFU P;  5IYB C;  3S17 C;  3I4N C;  1YNN A;  5JVG S;  1HQM A;  1VHY A;  4LK1 A;  4JYZ A;  5C44 C;  4OIR A;  4V19 4;  4YFK A;  2E2H C;  3PO3 C;  4QIW D;  4Y7N C;  3GTG C;  5BNZ A;  3PO2 C;  3PIO S;  4E8B A;  2NVT C;  4A3D C;  1I6H C;  1FEU A;  3HOX C;  4A3J C;  2JA7 C;  2R7Z C;  1TWG C;  4LJZ A;  2PI8 A;  4XSX A;  2B63 C;  3GTL C;  3M3Y C;  3LYW A;  4MQ9 A;  4C3H C;  4KMU A;  5IZN A;  3M4O C;  3S1M C;  2BE5 A;  4A3F C;  3HOU C;  3CF5 S;  3PIP S;  3S14 C;  4ZH4 A;  4G7O A;  2EGV A;  3RZD C;  4G7H A;  4G7Z A;  3GTK C;  2VUM C;  5C4J C;  5TMF A;  2E2I C;  4JK1 A;  4Q4Z A;  4J3C A;  4WF9 S;  2EGW A;  5IP9 C;  4Y52 C;  5TMC A;  4OIN A;  4A3I C;  1BDF A;  3H0G C;  5GAE W;  5IYD C;  1B75 A;  2NVX C;  4X6A C;  3S15 C;  4A3E C;  4P2B A;  3CZB A;  5DM6 S;  4YFN A;  5D4D A;  4UY8 8;  3HKZ D;  2HZ7 A;  2CX8 A;  1TWH C;  4U67 S;  1V6Z A;  2A6H A;  3GTM C;  3GTO C;  4A3M C;  1GTR A;  3GTP C;  5GAG W;  4H3S A;  2PIC A;  4JXZ A;  3W2W B;  1SFO C;  1QRT A;  4BXX C;  3S2D C;  1IW7 A;  4GZY A;  4OIP A;  1VHK A;  4MEY A;  1QTQ A;  1TWC C;  2ZJQ S;  3WOD A;  4XLN A;  1SMY A;  3DXJ A;  1D6K A;  2G5D A;  4BY7 C;  4A3L C;  1Y1W C;  4A3B C;  2RE8 A;  4MEX A;  2G6G A;  5IYC C;  2L5N A;  4QJV A;  1I3Q C;  3S1R C;  3J7Z V;  4C2M C;  2NVQ C;  5IP7 C;  3S2H C;  1TWA C;  5C4X C;  4WFN S;  1R9T C;  1TWF C;  2JA8 C;  2ZJP S;  1O0C A;  3GTQ C;  2R92 C;  2NVY C;  2A68 A;  2AE0 X;  2O5J A;  2Z0Y A;  3S1Q C;  1O0B A;  4OIQ A;  4A93 C;  4LK0 A;  4C3I C;  1UDX A;  4WCE S;  2WAQ D;  2PA8 D;  1Y1V C;  4KN4 A;  1EUQ A;  3HOY C;  5C3E C;  4YG2 A;  4BY1 C;  2O5I A;  3DLL S;  4JXX A;  4LLG A;  3S1N C;  3HOW C;  3KW2 A;  3K7A C;  4A3K C;  2E2J C;  2PPB A;  1WCM C;  5DM7 S;  2YU9 C;  2NWA A;  5JVH S;  2CW0 A;  2A6E A;  4OIO A;  2KPU A;  4YFX A;  1QRS A;  2GAE A;  1K83 C;  3EQL A;  1QRU A;  1Z85 A;  4A3G C;  3HOZ C;  5FLM C;  2L3U A;  4XLP A;  4Q5S A;  2ZJR S;  1NYL A;  4IOA S;  2R93 C;  2KQ1 A;  2PMZ D;  1EXD A;  1YNJ A;  3CQZ C;  4XSZ A;  1NXZ A;  2A69 A;  3RZO C;  5GAD W;  4BBS C;  2WB1 D;  2KXY A;  4A3C C;  3HOV C;  1ZJW A;  2JA5 C;  3W2V B;  1EUY A;  3I4M C;  4AYB D;  4H4K A;  1I50 C;  1ZYR A;  3AII A;  3S16 C;  2JA6 C;  4KN7 A;  4BBR C;  4IO9 S; 
#chains in the Genus database with same CATH homology
 1QTQ A;  2ZJQ S;  5GAH W;  3DLL S;  4JXX A;  5HL7 S;  1D6K A;  4WFB S;  4WFA S;  2RE8 A;  4WF9 S;  5DM7 S;  1GTS A;  2RD2 A;  5JVH S;  3X1L B;  4IOC S;  1DFU P;  1QRS A;  5JVG S;  3J7Z V;  1QRU A;  5GAE W;  4JYZ A;  1B75 A;  4V19 4;  4WFN S;  4P2B A;  5DM6 S;  2ZJP S;  5BNZ A;  2ZJR S;  1O0C A;  4UY8 8;  1NYL A;  2HZ7 A;  3PIO S;  4IOA S;  1FEU A;  4U67 S;  1O0B A;  1EXD A;  1GTR A;  5GAG W;  5GAD W;  4H3S A;  1ZJW A;  4JXZ A;  3W2W B;  1UDX A;  3W2V B;  5IZN A;  1EUY A;  4WCE S;  1QRT A;  3CF5 S;  3PIP S;  4H4K A;  3AII A;  1EUQ A;  4IO9 S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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