2ZKEA

Crystal structure of the sra domain of mouse np95 in complex with hemi-methylated cpg dna
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
210
structure length
210
Chain Sequence
SGMACVGRTTECTIVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Ligase
molecule keywords E3 ubiquitin-protein ligase UHRF1
publication title Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
pubmed doi rcsb
source organism Mus musculus
total genus 58
structure length 210
sequence length 210
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 2zkeA00
3FDEA 2ZKGA 3BI7A 3F8IA 2ZO2B 4NJ5A 3CLZA 2ZKFA 3OLNA 2ZKEA 2ZKDA 4PW5A 3DWHA 2ZO1B 2PB7A 3F8JB 2ZO0B 4PW6A 4PW7A
chains in the Genus database with same CATH superfamily
3FDEA 3Q0FA 2ZKGA 3BI7A 3F8IA 2ZO2B 4R28A 4NJ5A 3Q0CA 3CLZA 2ZKFA 4YGIA 3OLNA 2ZKEA 2ZKDA 4PW5A 4F0QA 3DWHA 2ZO1B 2PB7A 3F8JB 3Q0BX 4RZLA 2ZO0B 3Q0DA 4OC8A 4F0PA 4PW6A 4PW7A
chains in the Genus database with same CATH topology
3FDEA 2ZKGA 3BI7A 3F8IA 2ZO2B 4NJ5A 3CLZA 2ZKFA 3OLNA 2ZKEA 2ZKDA 4PW5A 3DWHA 2ZO1B 2PB7A 3F8JB 2ZO0B 4PW6A 4PW7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FDE A;  2ZKG A;  3BI7 A;  3F8I A;  2ZO2 B;  4NJ5 A;  3CLZ A;  2ZKF A;  3OLN A;  2ZKE A;  2ZKD A;  4PW5 A;  3DWH A;  2ZO1 B;  2PB7 A;  3F8J B;  2ZO0 B;  4PW6 A;  4PW7 A; 
#chains in the Genus database with same CATH topology
 3FDE A;  3Q0F A;  2ZKG A;  3BI7 A;  3F8I A;  2ZO2 B;  4R28 A;  4NJ5 A;  3Q0C A;  3CLZ A;  2ZKF A;  4YGI A;  3OLN A;  2ZKE A;  2ZKD A;  4PW5 A;  4F0Q A;  3DWH A;  2ZO1 B;  2PB7 A;  3F8J B;  3Q0B X;  4RZL A;  2ZO0 B;  3Q0D A;  4OC8 A;  4F0P A;  4PW6 A;  4PW7 A; 
#chains in the Genus database with same CATH homology
 3FDE A;  2ZKG A;  3BI7 A;  3F8I A;  2ZO2 B;  4NJ5 A;  3CLZ A;  2ZKF A;  3OLN A;  2ZKE A;  2ZKD A;  4PW5 A;  3DWH A;  2ZO1 B;  2PB7 A;  3F8J B;  2ZO0 B;  4PW6 A;  4PW7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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