2ZN7A

Crystal structures of ptp1b-inhibitor complexes
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 106
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2008-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2zn7A00
2CMAA 3I7ZA 3S3EA 2ZN7A 4GFUA 1G1FA 4GFVA 4YR8B 4GE6A 4QBWA 3AWFA 1OETA 2OUDA 2P4DA 2WGPA 1ZC0A 2G6ZA 2F6YA 1OEOX 3QCEA 4IKCA 1ONYA 4TVVA 5KADA 5J8RA 3M4UA 4D3QA 5K9VA 4BPCA 1FPRA 2B49A 5KABA 1AAXA 1WRMA 2PQ5A 2OZ5A 2I75A 3A5KA 1WAXA 4WOHA 2CM7A 4GRZA 1R6HA 1G1HA 4JMKA 3V0IA 2AZRA 2BGDA 2B3OA 1I9TA 3QCLA 1NWEA 4QAPA 4ZI4A 4WTYA 1LARA 2HXPA 2CNGA 3S3KA 2QDCA 5MMZB 3V0FA 4ZN5A 3CWEA 2QBPA 2F71A 5EHPA 4PYHA 2QBRA 1C85A 2I3RA 5KA4A 4NNDA 5M43A 2G59A 1YWFA 3QCNA 2I4HA 5KA9A 4ERCA 2QEPA 2BGEA 1ZCKA 4BJOA 2CM2A 2I4EA 3QCIA 1G7GA 3SR9A 1G1GA 1EENA 5IBSA 2B07A 1U24A 1RXDA 2F6ZA 2HVLA 5BZXA 1BZHA 1BZCA 1PTYA 1JLNA 1YN9A 2PI7A 2BZLA 2BIJA 2BV5A 2B4UA 3MOZA 2ESBA 1XBOA 4Y2EA 2P6XA 1YGRA 4J51A 2F6WA 4I8NA 3RO1A 3EU0A 4JNBA 4RI4A 1OHDA 1GWZA 3D9CA 5LXQB 3O4SA 1ZCLA 2MBCA 2CNEA 4R0TA 2FH7A 2J16B 3SMEA 3F9BA 3BM8A 2H02A 2NTAA 2QBSA 2B4OA 2HNPA 1YGUA 2YDUA 5BUGA 3OMHA 1J4XA 1EEOA 2CM8A 2H4GA 3RGOA 1OHCA 1C87A 3V0DA 1C84A 5KAAA 4NX8A 1YFOA 3O5XA 1PXHA 4JBCA 3V0EA 4OHLA 3EZZA 2GJTA 2F70A 2I42A 2I1YA 1P15A 5K22A 1NL9A 2F46A 2PA5A 5KA8A 1D5RA 1JF7A 2PSZA 3N0AA 1FQ1A 1G4WR 1XXPA 3F99A 2VEYA 4RI5A 1T48A 2CNHA 1MKPA 1Q6SA 2CMCA 2Q05A 5KA1A 3A5JA 3S3HA 1Q6TA 3EMUA 2HB1A 4KYRA 4RH9A 3CM3A 1VHRA 2A3KA 4GE5A 2I6MA 4OHDA 2H04A 1Q1MA 3AWEA 4WU2A 1PTTA 4S0GA 2A8BA 2DXPA 2OOQA 5GTJA 2Y2FA 1PTUA 4Y14A 2H4VA 2CNFA 4OHEA 4GRYA 1GFYA 4H34A 5BX1A 3QCMA 1QXKA 1PYNA 1T49A 3F41A 4KYQA 4GE2A 1ECVA 3ZV2A 2C46A 3ZM2A 1NWLA 2Q47A 1YTNA 3D1OA 3I36A 3EB1A 3QCJA 4QAHA 5EHRA 4D3PA 1NO6A 1SUGA 2B4PA 3NMEA 2CNIA 1X24A 4JMJA 1L8GA 3RGQA 1ZZWA 4RDDA 3MMJA 2H03A 3D42A 3QKPA 1YTSA 3ZMQA 5KA2A 3PS5A 5HDEA 2F6FA 3ZM3A 2H4KA 3GXHA 3ZM1A 3QCFA 2I5XA 2NT2A 3OLRA 2FJNA 3B7OA 5K25A 2I6IA 3S4OA 4HJQA 3QCGA 2I4GA 3S4EA 3QKQA 1U26A 4QBEA 2R0BA 3QCHA 4HRFA 2I6OA 4QUMA 1C83A 2VEUA 1M3GA 2CMBA 1V3AA 5K9WA 2I6JA 3QCCA 3D1HA 2QCJA 4Z6BA 3D44A 2QDPA 1XRIA 5IBMA 4NWGA 4DGXA 3QCKA 4MBBA 2NV5A 1RPMA 1OEMX 3RZ2A 1T4JA 2J17A 3O4UA 2QDMA 1C86A 2OC3A 2M3VA 2NZ6A 2VEXA 4H1OA 1I9SA 2HC1A 3BLUA 2AHSA 1LYVA 1U25A 1NZ7A 4OHHA 2PT0A 1Q6JA 1NNYA 1KAVA 1PA1A 1KAKA 1XXVA 2HY3A 2E0TA 2Y96A 3D1QA 3V0HA 1L8KA 1Q6PA 1BZJA 3U96A 1YZ4A 2VEVA 2GWOA 1PTVA 3QCBA 3I80A 2QCTA 5BZZA 5KA3A 1YPTA 2CJZA 2HCMA 1G4US 4ZRTA 3AWGA 4HJPA 4WU3A 2VEWA 1I57A 3O3LA 3O4TA 5I6VA 1Q6NA 4B04A 2ZMMA 2CFVA 1FPZA 4AZ1A 5KACA 2HC2A 1Q6MA 2JJDA 4QUNA 4R0SA 4DGPA 5KA7A 3MOWA 1QZ0A 4GS0A 4ICZA 4PVGA 2C7SA 1PA9A 1WCHA 2IMGA 3BLTA 2B4SA 3GXGA 2J16A 2PBNA 4KI9A 5KA0A 1OEVA 1OEUA 1OHEA 4NYHA 2I6PA 4RH5A 1YTWA 1PH0A 3LJ8A 4RHGA 1C88A 2NLKA 4R30A 1XM2A 2F6VA 4GWFA 1ONZA 4NWFA 3V0GA 4D3RA 3H2XA 2QBQA 3ZM0A 3ZMPA 2HNQA 2I3UA 2SHPA 1A5YA 2NT7A 1LQFA 2GP0A 1G7FA 1OESA 3V0JA 3BRHA 3S3FA 5K23A 2FJMA 3EAXA 2RF6A 3QCDA 4YAAA 5K24A 2F6TA 3F9AA 2CM3A 5AWXA 4OHIA 4RKKA 3F81A
chains in the Genus database with same CATH superfamily
2CMAA 3I7ZA 3S3EA 2ZN7A 4GFUA 1G1FA 4GFVA 4YR8B 4GE6A 4QBWA 3AWFA 1OETA 2OUDA 1UAGA 1JBWA 2VOSA 2P4DA 2WGPA 1ZC0A 2G6ZA 2F6YA 1OEOX 2JFFA 2UAGA 3QCEA 4IKCA 2WTZA 1ONYA 4TVVA 2VTDA 3N2AA 5KADA 5J8RA 3M4UA 4D3QA 5K9VA 4BPCA 1FPRA 1W7KA 2B49A 5KABA 1AAXA 1WRMA 2PQ5A 2OZ5A 2I75A 3A5KA 1WAXA 4WOHA 3UAGA 2CM7A 4GRZA 1R6HA 1G1HA 4JMKA 2GCBA 3V0IA 2AZRA 2BGDA 2B3OA 1I9TA 3QCLA 1NWEA 4UAGA 4QAPA 4ZI4A 4WTYA 1LARA 2HXPA 2CNGA 3S3KA 2QDCA 5MMZB 1E8CA 3QCZA 3V0FA 4ZN5A 2X5OA 3CWEA 2QBPA 2F71A 5EHPA 4PYHA 2QBRA 1C85A 2I3RA 5KA4A 4NNDA 5M43A 2G59A 2GCAA 1YWFA 3QCNA 2I4HA 5KA9A 4ERCA 2QEPA 2BGEA 1ZCKA 4BJOA 2CM2A 2I4EA 3QCIA 1G7GA 3SR9A 1G1GA 1EENA 5IBSA 2B07A 1U24A 1RXDA 2F6ZA 2HVLA 5BZXA 1BZHA 1BZCA 1PTYA 1JLNA 1YN9A 2GC6A 2JFGA 2PI7A 2BZLA 1O5ZA 2BIJA 2BV5A 2B4UA 3MOZA 2ESBA 1XBOA 4Y2EA 2P6XA 1YGRA 4J51A 2F6WA 4I8NA 3RO1A 3EU0A 4JNBA 4RI4A 1OHDA 1GWZA 3D9CA 5LXQB 3O4SA 1ZCLA 4BUCA 2MBCA 2CNEA 5A5EA 4R0TA 2FH7A 2Y68A 2J16B 3SMEA 3F9BA 3BM8A 2H02A 2NTAA 2QBSA 2B4OA 2HNPA 1YGUA 2YDUA 5BUGA 3OMHA 1J4XA 1EEOA 2UUPA 2CM8A 2H4GA 3RGOA 1OHCA 1C87A 3V0DA 1C84A 5KAAA 3ZM6A 4NX8A 1YFOA 4BUBA 3O5XA 1PXHA 4JBCA 3V0EA 4OHLA 3EZZA 1E0DA 2GJTA 2F70A 2I42A 2I1YA 2GC5A 1P15A 5K22A 1NL9A 2F46A 2PA5A 5KA8A 1GQYA 1D5RA 1JF7A 2PSZA 3N0AA 1FQ1A 1W78A 1G4WR 2AM2A 1XXPA 3F99A 2VEYA 3ZL8A 4RI5A 1T48A 3HN7A 2CNHA 1MKPA 1Q6SA 2CMCA 2Q05A 5KA1A 3A5JA 3S3HA 4HV4A 1Q6TA 3EMUA 2HB1A 4KYRA 4RH9A 3CM3A 1VHRA 2A3KA 4GE5A 2I6MA 4OHDA 2H04A 1Q1MA 3AWEA 4WU2A 1PTTA 4S0GA 1P3DA 2A8BA 2DXPA 2OOQA 5GTJA 2Y2FA 1PTUA 4Y14A 2H4VA 2CNFA 4OHEA 4GRYA 1GFYA 4H34A 5BX1A 3QCMA 1QXKA 1PYNA 1T49A 3F41A 4KYQA 2XJAA 4GE2A 1ECVA 3ZV2A 2C46A 2F00A 3ZM2A 3PYZA 1NWLA 2Q47A 1YTNA 3D1OA 3I36A 3EB1A 3QCJA 4QAHA 5EHRA 4D3PA 1NO6A 1SUGA 2B4PA 5A5FA 3NMEA 2CNIA 1X24A 2UUOA 4JMJA 1L8GA 3RGQA 1ZZWA 4RDDA 3LK7A 2Y1OA 3MMJA 2H03A 3D42A 3QKPA 1YTSA 3ZMQA 5KA2A 3PS5A 5HDEA 2WJPA 2F6FA 2VORA 3ZM3A 2H4KA 3GXHA 3ZM1A 3QCFA 2I5XA 2NT2A 3OLRA 2FJNA 3B7OA 3NRSA 5K25A 2I6IA 3S4OA 4HJQA 3QCGA 2I4GA 4C13A 3S4EA 3QKQA 1U26A 4QBEA 2R0BA 3QCHA 4HRFA 2I6OA 2VTEA 4QUMA 1C83A 2XPCA 2VEUA 1M3GA 2CMBA 1V3AA 5K9WA 4CVMA 2I6JA 3QCCA 3D1HA 2QCJA 1P31A 4Z6BA 3D44A 2QDPA 1XRIA 5IBMA 4NWGA 4DGXA 3QCKA 4MBBA 2NV5A 1RPMA 1OEMX 1EEHA 3RZ2A 1T4JA 2J17A 3O4UA 2AM1A 2QDMA 1C86A 2OC3A 2M3VA 2NZ6A 2VEXA 4H1OA 1J6UA 1I9SA 2HC1A 3BLUA 2AHSA 1LYVA 1U25A 1NZ7A 4OHHA 2PT0A 1Q6JA 1NNYA 1KAVA 1PA1A 1KAKA 1XXVA 2HY3A 1GQQA 2E0TA 2Y96A 3D1QA 3V0HA 1L8KA 1Q6PA 1BZJA 3U96A 2JFHA 1YZ4A 2VEVA 4CVLA 2GWOA 1PTVA 3QCBA 3I80A 2QCTA 1FGSA 4QDIA 5BZZA 5KA3A 1YPTA 2CJZA 2HCMA 2Y66A 1G4US 4ZRTA 3AWGA 4HJPA 4WU3A 2VEWA 1I57A 3O3LA 3O4TA 5I6VA 1Q6NA 4B04A 2ZMMA 2CFVA 2Y67A 1FPZA 4AZ1A 5KACA 2HC2A 1Q6MA 2JJDA 4QUNA 4R0SA 4DGPA 5KA7A 3MOWA 1QZ0A 4GS0A 4ICZA 4PVGA 2C7SA 1PA9A 1WCHA 2IMGA 3BLTA 2B4SA 3GXGA 2J16A 4CVKA 2PBNA 4KI9A 5KA0A 1OEVA 1OEUA 1OHEA 4NYHA 2I6PA 4RH5A 1YTWA 1PH0A 3LJ8A 4RHGA 4C12A 1C88A 2NLKA 4R30A 1XM2A 2F6VA 4GWFA 1ONZA 4NWFA 3V0GA 4D3RA 3H2XA 2QBQA 3ZM0A 3ZMPA 4ZIYA 2HNQA 2I3UA 2SHPA 1A5YA 1GG4A 3ZM5A 2NT7A 1LQFA 2GP0A 1G7FA 1OESA 4QF5A 3V0JA 1JBVA 3BRHA 3S3FA 5K23A 2FJMA 3EAXA 2RF6A 3QCDA 4YAAA 3MVNA 5K24A 2F6TA 3F9AA 2CM3A 5AWXA 4OHIA 4RKKA 3F81A
chains in the Genus database with same CATH topology
2CMAA 3I7ZA 3S3EA 2ZN7A 4GFUA 1G1FA 4GFVA 4YR8B 4GE6A 4QBWA 3AWFA 1OETA 2OUDA 2P4DA 2WGPA 1ZC0A 2G6ZA 2F6YA 1OEOX 3QCEA 4IKCA 1ONYA 4TVVA 5KADA 5J8RA 3M4UA 4D3QA 5K9VA 4BPCA 1FPRA 2B49A 5KABA 1AAXA 1WRMA 2PQ5A 2OZ5A 2I75A 3A5KA 1WAXA 4WOHA 2CM7A 4GRZA 1R6HA 1G1HA 4JMKA 3V0IA 2AZRA 2BGDA 2B3OA 1I9TA 3QCLA 1NWEA 4QAPA 4ZI4A 4WTYA 1LARA 2HXPA 2CNGA 3S3KA 2QDCA 5MMZB 3V0FA 4ZN5A 3CWEA 2QBPA 2F71A 5EHPA 4PYHA 2QBRA 1C85A 2I3RA 5KA4A 4NNDA 5M43A 2G59A 1YWFA 3QCNA 2I4HA 5KA9A 4ERCA 2QEPA 2BGEA 1ZCKA 4BJOA 2CM2A 2I4EA 3QCIA 1G7GA 3SR9A 1G1GA 1EENA 5IBSA 2B07A 1U24A 1RXDA 2F6ZA 2HVLA 5BZXA 1BZHA 1BZCA 1PTYA 1JLNA 1YN9A 2PI7A 2BZLA 2BIJA 2BV5A 2B4UA 3MOZA 2ESBA 1XBOA 4Y2EA 2P6XA 1YGRA 4J51A 2F6WA 4I8NA 3RO1A 3EU0A 4JNBA 4RI4A 1OHDA 1GWZA 3D9CA 5LXQB 3O4SA 1ZCLA 2MBCA 2CNEA 4R0TA 2FH7A 2J16B 3SMEA 3F9BA 3BM8A 2H02A 2NTAA 2QBSA 2B4OA 2HNPA 1YGUA 2YDUA 5BUGA 3OMHA 1J4XA 1EEOA 2CM8A 2H4GA 3RGOA 1OHCA 1C87A 3V0DA 1C84A 5KAAA 4NX8A 1YFOA 3O5XA 1PXHA 4JBCA 3V0EA 4OHLA 3EZZA 2GJTA 2F70A 2I42A 2I1YA 1P15A 5K22A 1NL9A 2F46A 2PA5A 5KA8A 1D5RA 1JF7A 2PSZA 3N0AA 1FQ1A 1G4WR 1XXPA 3F99A 2VEYA 4RI5A 1T48A 2CNHA 1MKPA 1Q6SA 2CMCA 2Q05A 5KA1A 3A5JA 3S3HA 1Q6TA 3EMUA 2HB1A 4KYRA 4RH9A 3CM3A 1VHRA 2A3KA 4GE5A 2I6MA 4OHDA 2H04A 1Q1MA 3AWEA 4WU2A 1PTTA 4S0GA 2A8BA 2DXPA 2OOQA 5GTJA 2Y2FA 1PTUA 4Y14A 2H4VA 2CNFA 4OHEA 4GRYA 1GFYA 4H34A 5BX1A 3QCMA 1QXKA 1PYNA 1T49A 3F41A 4KYQA 4GE2A 1ECVA 3ZV2A 2C46A 3ZM2A 1NWLA 2Q47A 1YTNA 3D1OA 3I36A 3EB1A 3QCJA 4QAHA 5EHRA 4D3PA 1NO6A 1SUGA 2B4PA 3NMEA 2CNIA 1X24A 4JMJA 1L8GA 3RGQA 1ZZWA 4RDDA 3MMJA 2H03A 3D42A 3QKPA 1YTSA 3ZMQA 5KA2A 3PS5A 5HDEA 2F6FA 3ZM3A 2H4KA 3GXHA 3ZM1A 3QCFA 2I5XA 2NT2A 3OLRA 2FJNA 3B7OA 5K25A 2I6IA 3S4OA 4HJQA 3QCGA 2I4GA 3S4EA 3QKQA 1U26A 4QBEA 2R0BA 3QCHA 4HRFA 2I6OA 4QUMA 1C83A 2VEUA 1M3GA 2CMBA 1V3AA 5K9WA 2I6JA 3QCCA 3D1HA 2QCJA 4Z6BA 3D44A 2QDPA 1XRIA 5IBMA 4NWGA 4DGXA 3QCKA 4MBBA 2NV5A 1RPMA 1OEMX 3RZ2A 1T4JA 2J17A 3O4UA 2QDMA 1C86A 2OC3A 2M3VA 2NZ6A 2VEXA 4H1OA 1I9SA 2HC1A 3BLUA 2AHSA 1LYVA 1U25A 1NZ7A 4OHHA 2PT0A 1Q6JA 1NNYA 1KAVA 1PA1A 1KAKA 1XXVA 2HY3A 2E0TA 2Y96A 3D1QA 3V0HA 1L8KA 1Q6PA 1BZJA 3U96A 1YZ4A 2VEVA 2GWOA 1PTVA 3QCBA 3I80A 2QCTA 5BZZA 5KA3A 1YPTA 2CJZA 2HCMA 1G4US 4ZRTA 3AWGA 4HJPA 4WU3A 2VEWA 1I57A 3O3LA 3O4TA 5I6VA 1Q6NA 4B04A 2ZMMA 2CFVA 1FPZA 4AZ1A 5KACA 2HC2A 1Q6MA 2JJDA 4QUNA 4R0SA 4DGPA 5KA7A 3MOWA 1QZ0A 4GS0A 4ICZA 4PVGA 2C7SA 1PA9A 1WCHA 2IMGA 3BLTA 2B4SA 3GXGA 2J16A 2PBNA 4KI9A 5KA0A 1OEVA 1OEUA 1OHEA 4NYHA 2I6PA 4RH5A 1YTWA 1PH0A 3LJ8A 4RHGA 1C88A 2NLKA 4R30A 1XM2A 2F6VA 4GWFA 1ONZA 4NWFA 3V0GA 4D3RA 3H2XA 2QBQA 3ZM0A 3ZMPA 2HNQA 2I3UA 2SHPA 1A5YA 2NT7A 1LQFA 2GP0A 1G7FA 1OESA 3V0JA 3BRHA 3S3FA 5K23A 2FJMA 3EAXA 2RF6A 3QCDA 4YAAA 5K24A 2F6TA 3F9AA 2CM3A 5AWXA 4OHIA 4RKKA 3F81A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CMA A;  3I7Z A;  3S3E A;  2ZN7 A;  4GFU A;  1G1F A;  4GFV A;  4YR8 B;  4GE6 A;  4QBW A;  3AWF A;  1OET A;  2OUD A;  2P4D A;  2WGP A;  1ZC0 A;  2G6Z A;  2F6Y A;  1OEO X;  3QCE A;  4IKC A;  1ONY A;  4TVV A;  5KAD A;  5J8R A;  3M4U A;  4D3Q A;  5K9V A;  4BPC A;  1FPR A;  2B49 A;  5KAB A;  1AAX A;  1WRM A;  2PQ5 A;  2OZ5 A;  2I75 A;  3A5K A;  1WAX A;  4WOH A;  2CM7 A;  4GRZ A;  1R6H A;  1G1H A;  4JMK A;  3V0I A;  2AZR A;  2BGD A;  2B3O A;  1I9T A;  3QCL A;  1NWE A;  4QAP A;  4ZI4 A;  4WTY A;  1LAR A;  2HXP A;  2CNG A;  3S3K A;  2QDC A;  5MMZ B;  3V0F A;  4ZN5 A;  3CWE A;  2QBP A;  2F71 A;  5EHP A;  4PYH A;  2QBR A;  1C85 A;  2I3R A;  5KA4 A;  4NND A;  5M43 A;  2G59 A;  1YWF A;  3QCN A;  2I4H A;  5KA9 A;  4ERC A;  2QEP A;  2BGE A;  1ZCK A;  4BJO A;  2CM2 A;  2I4E A;  3QCI A;  1G7G A;  3SR9 A;  1G1G A;  1EEN A;  5IBS A;  2B07 A;  1U24 A;  1RXD A;  2F6Z A;  2HVL A;  5BZX A;  1BZH A;  1BZC A;  1PTY A;  1JLN A;  1YN9 A;  2PI7 A;  2BZL A;  2BIJ A;  2BV5 A;  2B4U A;  3MOZ A;  2ESB A;  1XBO A;  4Y2E A;  2P6X A;  1YGR A;  4J51 A;  2F6W A;  4I8N A;  3RO1 A;  3EU0 A;  4JNB A;  4RI4 A;  1OHD A;  1GWZ A;  3D9C A;  5LXQ B;  3O4S A;  1ZCL A;  2MBC A;  2CNE A;  4R0T A;  2FH7 A;  2J16 B;  3SME A;  3F9B A;  3BM8 A;  2H02 A;  2NTA A;  2QBS A;  2B4O A;  2HNP A;  1YGU A;  2YDU A;  5BUG A;  3OMH A;  1J4X A;  1EEO A;  2CM8 A;  2H4G A;  3RGO A;  1OHC A;  1C87 A;  3V0D A;  1C84 A;  5KAA A;  4NX8 A;  1YFO A;  3O5X A;  1PXH A;  4JBC A;  3V0E A;  4OHL A;  3EZZ A;  2GJT A;  2F70 A;  2I42 A;  2I1Y A;  1P15 A;  5K22 A;  1NL9 A;  2F46 A;  2PA5 A;  5KA8 A;  1D5R A;  1JF7 A;  2PSZ A;  3N0A A;  1FQ1 A;  1G4W R;  1XXP A;  3F99 A;  2VEY A;  4RI5 A;  1T48 A;  2CNH A;  1MKP A;  1Q6S A;  2CMC A;  2Q05 A;  5KA1 A;  3A5J A;  3S3H A;  1Q6T A;  3EMU A;  2HB1 A;  4KYR A;  4RH9 A;  3CM3 A;  1VHR A;  2A3K A;  4GE5 A;  2I6M A;  4OHD A;  2H04 A;  1Q1M A;  3AWE A;  4WU2 A;  1PTT A;  4S0G A;  2A8B A;  2DXP A;  2OOQ A;  5GTJ A;  2Y2F A;  1PTU A;  4Y14 A;  2H4V A;  2CNF A;  4OHE A;  4GRY A;  1GFY A;  4H34 A;  5BX1 A;  3QCM A;  1QXK A;  1PYN A;  1T49 A;  3F41 A;  4KYQ A;  4GE2 A;  1ECV A;  3ZV2 A;  2C46 A;  3ZM2 A;  1NWL A;  2Q47 A;  1YTN A;  3D1O A;  3I36 A;  3EB1 A;  3QCJ A;  4QAH A;  5EHR A;  4D3P A;  1NO6 A;  1SUG A;  2B4P A;  3NME A;  2CNI A;  1X24 A;  4JMJ A;  1L8G A;  3RGQ A;  1ZZW A;  4RDD A;  3MMJ A;  2H03 A;  3D42 A;  3QKP A;  1YTS A;  3ZMQ A;  5KA2 A;  3PS5 A;  5HDE A;  2F6F A;  3ZM3 A;  2H4K A;  3GXH A;  3ZM1 A;  3QCF A;  2I5X A;  2NT2 A;  3OLR A;  2FJN A;  3B7O A;  5K25 A;  2I6I A;  3S4O A;  4HJQ A;  3QCG A;  2I4G A;  3S4E A;  3QKQ A;  1U26 A;  4QBE A;  2R0B A;  3QCH A;  4HRF A;  2I6O A;  4QUM A;  1C83 A;  2VEU A;  1M3G A;  2CMB A;  1V3A A;  5K9W A;  2I6J A;  3QCC A;  3D1H A;  2QCJ A;  4Z6B A;  3D44 A;  2QDP A;  1XRI A;  5IBM A;  4NWG A;  4DGX A;  3QCK A;  4MBB A;  2NV5 A;  1RPM A;  1OEM X;  3RZ2 A;  1T4J A;  2J17 A;  3O4U A;  2QDM A;  1C86 A;  2OC3 A;  2M3V A;  2NZ6 A;  2VEX A;  4H1O A;  1I9S A;  2HC1 A;  3BLU A;  2AHS A;  1LYV A;  1U25 A;  1NZ7 A;  4OHH A;  2PT0 A;  1Q6J A;  1NNY A;  1KAV A;  1PA1 A;  1KAK A;  1XXV A;  2HY3 A;  2E0T A;  2Y96 A;  3D1Q A;  3V0H A;  1L8K A;  1Q6P A;  1BZJ A;  3U96 A;  1YZ4 A;  2VEV A;  2GWO A;  1PTV A;  3QCB A;  3I80 A;  2QCT A;  5BZZ A;  5KA3 A;  1YPT A;  2CJZ A;  2HCM A;  1G4U S;  4ZRT A;  3AWG A;  4HJP A;  4WU3 A;  2VEW A;  1I57 A;  3O3L A;  3O4T A;  5I6V A;  1Q6N A;  4B04 A;  2ZMM A;  2CFV A;  1FPZ A;  4AZ1 A;  5KAC A;  2HC2 A;  1Q6M A;  2JJD A;  4QUN A;  4R0S A;  4DGP A;  5KA7 A;  3MOW A;  1QZ0 A;  4GS0 A;  4ICZ A;  4PVG A;  2C7S A;  1PA9 A;  1WCH A;  2IMG A;  3BLT A;  2B4S A;  3GXG A;  2J16 A;  2PBN A;  4KI9 A;  5KA0 A;  1OEV A;  1OEU A;  1OHE A;  4NYH A;  2I6P A;  4RH5 A;  1YTW A;  1PH0 A;  3LJ8 A;  4RHG A;  1C88 A;  2NLK A;  4R30 A;  1XM2 A;  2F6V A;  4GWF A;  1ONZ A;  4NWF A;  3V0G A;  4D3R A;  3H2X A;  2QBQ A;  3ZM0 A;  3ZMP A;  2HNQ A;  2I3U A;  2SHP A;  1A5Y A;  2NT7 A;  1LQF A;  2GP0 A;  1G7F A;  1OES A;  3V0J A;  3BRH A;  3S3F A;  5K23 A;  2FJM A;  3EAX A;  2RF6 A;  3QCD A;  4YAA A;  5K24 A;  2F6T A;  3F9A A;  2CM3 A;  5AWX A;  4OHI A;  4RKK A;  3F81 A; 
#chains in the Genus database with same CATH topology
 2CMA A;  3I7Z A;  3S3E A;  2ZN7 A;  4GFU A;  1G1F A;  4GFV A;  4YR8 B;  4GE6 A;  4QBW A;  3AWF A;  1OET A;  2OUD A;  1UAG A;  1JBW A;  2VOS A;  2P4D A;  2WGP A;  1ZC0 A;  2G6Z A;  2F6Y A;  1OEO X;  2JFF A;  2UAG A;  3QCE A;  4IKC A;  2WTZ A;  1ONY A;  4TVV A;  2VTD A;  3N2A A;  5KAD A;  5J8R A;  3M4U A;  4D3Q A;  5K9V A;  4BPC A;  1FPR A;  1W7K A;  2B49 A;  5KAB A;  1AAX A;  1WRM A;  2PQ5 A;  2OZ5 A;  2I75 A;  3A5K A;  1WAX A;  4WOH A;  3UAG A;  2CM7 A;  4GRZ A;  1R6H A;  1G1H A;  4JMK A;  2GCB A;  3V0I A;  2AZR A;  2BGD A;  2B3O A;  1I9T A;  3QCL A;  1NWE A;  4UAG A;  4QAP A;  4ZI4 A;  4WTY A;  1LAR A;  2HXP A;  2CNG A;  3S3K A;  2QDC A;  5MMZ B;  1E8C A;  3QCZ A;  3V0F A;  4ZN5 A;  2X5O A;  3CWE A;  2QBP A;  2F71 A;  5EHP A;  4PYH A;  2QBR A;  1C85 A;  2I3R A;  5KA4 A;  4NND A;  5M43 A;  2G59 A;  2GCA A;  1YWF A;  3QCN A;  2I4H A;  5KA9 A;  4ERC A;  2QEP A;  2BGE A;  1ZCK A;  4BJO A;  2CM2 A;  2I4E A;  3QCI A;  1G7G A;  3SR9 A;  1G1G A;  1EEN A;  5IBS A;  2B07 A;  1U24 A;  1RXD A;  2F6Z A;  2HVL A;  5BZX A;  1BZH A;  1BZC A;  1PTY A;  1JLN A;  1YN9 A;  2GC6 A;  2JFG A;  2PI7 A;  2BZL A;  1O5Z A;  2BIJ A;  2BV5 A;  2B4U A;  3MOZ A;  2ESB A;  1XBO A;  4Y2E A;  2P6X A;  1YGR A;  4J51 A;  2F6W A;  4I8N A;  3RO1 A;  3EU0 A;  4JNB A;  4RI4 A;  1OHD A;  1GWZ A;  3D9C A;  5LXQ B;  3O4S A;  1ZCL A;  4BUC A;  2MBC A;  2CNE A;  5A5E A;  4R0T A;  2FH7 A;  2Y68 A;  2J16 B;  3SME A;  3F9B A;  3BM8 A;  2H02 A;  2NTA A;  2QBS A;  2B4O A;  2HNP A;  1YGU A;  2YDU A;  5BUG A;  3OMH A;  1J4X A;  1EEO A;  2UUP A;  2CM8 A;  2H4G A;  3RGO A;  1OHC A;  1C87 A;  3V0D A;  1C84 A;  5KAA A;  3ZM6 A;  4NX8 A;  1YFO A;  4BUB A;  3O5X A;  1PXH A;  4JBC A;  3V0E A;  4OHL A;  3EZZ A;  1E0D A;  2GJT A;  2F70 A;  2I42 A;  2I1Y A;  2GC5 A;  1P15 A;  5K22 A;  1NL9 A;  2F46 A;  2PA5 A;  5KA8 A;  1GQY A;  1D5R A;  1JF7 A;  2PSZ A;  3N0A A;  1FQ1 A;  1W78 A;  1G4W R;  2AM2 A;  1XXP A;  3F99 A;  2VEY A;  3ZL8 A;  4RI5 A;  1T48 A;  3HN7 A;  2CNH A;  1MKP A;  1Q6S A;  2CMC A;  2Q05 A;  5KA1 A;  3A5J A;  3S3H A;  4HV4 A;  1Q6T A;  3EMU A;  2HB1 A;  4KYR A;  4RH9 A;  3CM3 A;  1VHR A;  2A3K A;  4GE5 A;  2I6M A;  4OHD A;  2H04 A;  1Q1M A;  3AWE A;  4WU2 A;  1PTT A;  4S0G A;  1P3D A;  2A8B A;  2DXP A;  2OOQ A;  5GTJ A;  2Y2F A;  1PTU A;  4Y14 A;  2H4V A;  2CNF A;  4OHE A;  4GRY A;  1GFY A;  4H34 A;  5BX1 A;  3QCM A;  1QXK A;  1PYN A;  1T49 A;  3F41 A;  4KYQ A;  2XJA A;  4GE2 A;  1ECV A;  3ZV2 A;  2C46 A;  2F00 A;  3ZM2 A;  3PYZ A;  1NWL A;  2Q47 A;  1YTN A;  3D1O A;  3I36 A;  3EB1 A;  3QCJ A;  4QAH A;  5EHR A;  4D3P A;  1NO6 A;  1SUG A;  2B4P A;  5A5F A;  3NME A;  2CNI A;  1X24 A;  2UUO A;  4JMJ A;  1L8G A;  3RGQ A;  1ZZW A;  4RDD A;  3LK7 A;  2Y1O A;  3MMJ A;  2H03 A;  3D42 A;  3QKP A;  1YTS A;  3ZMQ A;  5KA2 A;  3PS5 A;  5HDE A;  2WJP A;  2F6F A;  2VOR A;  3ZM3 A;  2H4K A;  3GXH A;  3ZM1 A;  3QCF A;  2I5X A;  2NT2 A;  3OLR A;  2FJN A;  3B7O A;  3NRS A;  5K25 A;  2I6I A;  3S4O A;  4HJQ A;  3QCG A;  2I4G A;  4C13 A;  3S4E A;  3QKQ A;  1U26 A;  4QBE A;  2R0B A;  3QCH A;  4HRF A;  2I6O A;  2VTE A;  4QUM A;  1C83 A;  2XPC A;  2VEU A;  1M3G A;  2CMB A;  1V3A A;  5K9W A;  4CVM A;  2I6J A;  3QCC A;  3D1H A;  2QCJ A;  1P31 A;  4Z6B A;  3D44 A;  2QDP A;  1XRI A;  5IBM A;  4NWG A;  4DGX A;  3QCK A;  4MBB A;  2NV5 A;  1RPM A;  1OEM X;  1EEH A;  3RZ2 A;  1T4J A;  2J17 A;  3O4U A;  2AM1 A;  2QDM A;  1C86 A;  2OC3 A;  2M3V A;  2NZ6 A;  2VEX A;  4H1O A;  1J6U A;  1I9S A;  2HC1 A;  3BLU A;  2AHS A;  1LYV A;  1U25 A;  1NZ7 A;  4OHH A;  2PT0 A;  1Q6J A;  1NNY A;  1KAV A;  1PA1 A;  1KAK A;  1XXV A;  2HY3 A;  1GQQ A;  2E0T A;  2Y96 A;  3D1Q A;  3V0H A;  1L8K A;  1Q6P A;  1BZJ A;  3U96 A;  2JFH A;  1YZ4 A;  2VEV A;  4CVL A;  2GWO A;  1PTV A;  3QCB A;  3I80 A;  2QCT A;  1FGS A;  4QDI A;  5BZZ A;  5KA3 A;  1YPT A;  2CJZ A;  2HCM A;  2Y66 A;  1G4U S;  4ZRT A;  3AWG A;  4HJP A;  4WU3 A;  2VEW A;  1I57 A;  3O3L A;  3O4T A;  5I6V A;  1Q6N A;  4B04 A;  2ZMM A;  2CFV A;  2Y67 A;  1FPZ A;  4AZ1 A;  5KAC A;  2HC2 A;  1Q6M A;  2JJD A;  4QUN A;  4R0S A;  4DGP A;  5KA7 A;  3MOW A;  1QZ0 A;  4GS0 A;  4ICZ A;  4PVG A;  2C7S A;  1PA9 A;  1WCH A;  2IMG A;  3BLT A;  2B4S A;  3GXG A;  2J16 A;  4CVK A;  2PBN A;  4KI9 A;  5KA0 A;  1OEV A;  1OEU A;  1OHE A;  4NYH A;  2I6P A;  4RH5 A;  1YTW A;  1PH0 A;  3LJ8 A;  4RHG A;  4C12 A;  1C88 A;  2NLK A;  4R30 A;  1XM2 A;  2F6V A;  4GWF A;  1ONZ A;  4NWF A;  3V0G A;  4D3R A;  3H2X A;  2QBQ A;  3ZM0 A;  3ZMP A;  4ZIY A;  2HNQ A;  2I3U A;  2SHP A;  1A5Y A;  1GG4 A;  3ZM5 A;  2NT7 A;  1LQF A;  2GP0 A;  1G7F A;  1OES A;  4QF5 A;  3V0J A;  1JBV A;  3BRH A;  3S3F A;  5K23 A;  2FJM A;  3EAX A;  2RF6 A;  3QCD A;  4YAA A;  3MVN A;  5K24 A;  2F6T A;  3F9A A;  2CM3 A;  5AWX A;  4OHI A;  4RKK A;  3F81 A; 
#chains in the Genus database with same CATH homology
 2CMA A;  3I7Z A;  3S3E A;  2ZN7 A;  4GFU A;  1G1F A;  4GFV A;  4YR8 B;  4GE6 A;  4QBW A;  3AWF A;  1OET A;  2OUD A;  2P4D A;  2WGP A;  1ZC0 A;  2G6Z A;  2F6Y A;  1OEO X;  3QCE A;  4IKC A;  1ONY A;  4TVV A;  5KAD A;  5J8R A;  3M4U A;  4D3Q A;  5K9V A;  4BPC A;  1FPR A;  2B49 A;  5KAB A;  1AAX A;  1WRM A;  2PQ5 A;  2OZ5 A;  2I75 A;  3A5K A;  1WAX A;  4WOH A;  2CM7 A;  4GRZ A;  1R6H A;  1G1H A;  4JMK A;  3V0I A;  2AZR A;  2BGD A;  2B3O A;  1I9T A;  3QCL A;  1NWE A;  4QAP A;  4ZI4 A;  4WTY A;  1LAR A;  2HXP A;  2CNG A;  3S3K A;  2QDC A;  5MMZ B;  3V0F A;  4ZN5 A;  3CWE A;  2QBP A;  2F71 A;  5EHP A;  4PYH A;  2QBR A;  1C85 A;  2I3R A;  5KA4 A;  4NND A;  5M43 A;  2G59 A;  1YWF A;  3QCN A;  2I4H A;  5KA9 A;  4ERC A;  2QEP A;  2BGE A;  1ZCK A;  4BJO A;  2CM2 A;  2I4E A;  3QCI A;  1G7G A;  3SR9 A;  1G1G A;  1EEN A;  5IBS A;  2B07 A;  1U24 A;  1RXD A;  2F6Z A;  2HVL A;  5BZX A;  1BZH A;  1BZC A;  1PTY A;  1JLN A;  1YN9 A;  2PI7 A;  2BZL A;  2BIJ A;  2BV5 A;  2B4U A;  3MOZ A;  2ESB A;  1XBO A;  4Y2E A;  2P6X A;  1YGR A;  4J51 A;  2F6W A;  4I8N A;  3RO1 A;  3EU0 A;  4JNB A;  4RI4 A;  1OHD A;  1GWZ A;  3D9C A;  5LXQ B;  3O4S A;  1ZCL A;  2MBC A;  2CNE A;  4R0T A;  2FH7 A;  2J16 B;  3SME A;  3F9B A;  3BM8 A;  2H02 A;  2NTA A;  2QBS A;  2B4O A;  2HNP A;  1YGU A;  2YDU A;  5BUG A;  3OMH A;  1J4X A;  1EEO A;  2CM8 A;  2H4G A;  3RGO A;  1OHC A;  1C87 A;  3V0D A;  1C84 A;  5KAA A;  4NX8 A;  1YFO A;  3O5X A;  1PXH A;  4JBC A;  3V0E A;  4OHL A;  3EZZ A;  2GJT A;  2F70 A;  2I42 A;  2I1Y A;  1P15 A;  5K22 A;  1NL9 A;  2F46 A;  2PA5 A;  5KA8 A;  1D5R A;  1JF7 A;  2PSZ A;  3N0A A;  1FQ1 A;  1G4W R;  1XXP A;  3F99 A;  2VEY A;  4RI5 A;  1T48 A;  2CNH A;  1MKP A;  1Q6S A;  2CMC A;  2Q05 A;  5KA1 A;  3A5J A;  3S3H A;  1Q6T A;  3EMU A;  2HB1 A;  4KYR A;  4RH9 A;  3CM3 A;  1VHR A;  2A3K A;  4GE5 A;  2I6M A;  4OHD A;  2H04 A;  1Q1M A;  3AWE A;  4WU2 A;  1PTT A;  4S0G A;  2A8B A;  2DXP A;  2OOQ A;  5GTJ A;  2Y2F A;  1PTU A;  4Y14 A;  2H4V A;  2CNF A;  4OHE A;  4GRY A;  1GFY A;  4H34 A;  5BX1 A;  3QCM A;  1QXK A;  1PYN A;  1T49 A;  3F41 A;  4KYQ A;  4GE2 A;  1ECV A;  3ZV2 A;  2C46 A;  3ZM2 A;  1NWL A;  2Q47 A;  1YTN A;  3D1O A;  3I36 A;  3EB1 A;  3QCJ A;  4QAH A;  5EHR A;  4D3P A;  1NO6 A;  1SUG A;  2B4P A;  3NME A;  2CNI A;  1X24 A;  4JMJ A;  1L8G A;  3RGQ A;  1ZZW A;  4RDD A;  3MMJ A;  2H03 A;  3D42 A;  3QKP A;  1YTS A;  3ZMQ A;  5KA2 A;  3PS5 A;  5HDE A;  2F6F A;  3ZM3 A;  2H4K A;  3GXH A;  3ZM1 A;  3QCF A;  2I5X A;  2NT2 A;  3OLR A;  2FJN A;  3B7O A;  5K25 A;  2I6I A;  3S4O A;  4HJQ A;  3QCG A;  2I4G A;  3S4E A;  3QKQ A;  1U26 A;  4QBE A;  2R0B A;  3QCH A;  4HRF A;  2I6O A;  4QUM A;  1C83 A;  2VEU A;  1M3G A;  2CMB A;  1V3A A;  5K9W A;  2I6J A;  3QCC A;  3D1H A;  2QCJ A;  4Z6B A;  3D44 A;  2QDP A;  1XRI A;  5IBM A;  4NWG A;  4DGX A;  3QCK A;  4MBB A;  2NV5 A;  1RPM A;  1OEM X;  3RZ2 A;  1T4J A;  2J17 A;  3O4U A;  2QDM A;  1C86 A;  2OC3 A;  2M3V A;  2NZ6 A;  2VEX A;  4H1O A;  1I9S A;  2HC1 A;  3BLU A;  2AHS A;  1LYV A;  1U25 A;  1NZ7 A;  4OHH A;  2PT0 A;  1Q6J A;  1NNY A;  1KAV A;  1PA1 A;  1KAK A;  1XXV A;  2HY3 A;  2E0T A;  2Y96 A;  3D1Q A;  3V0H A;  1L8K A;  1Q6P A;  1BZJ A;  3U96 A;  1YZ4 A;  2VEV A;  2GWO A;  1PTV A;  3QCB A;  3I80 A;  2QCT A;  5BZZ A;  5KA3 A;  1YPT A;  2CJZ A;  2HCM A;  1G4U S;  4ZRT A;  3AWG A;  4HJP A;  4WU3 A;  2VEW A;  1I57 A;  3O3L A;  3O4T A;  5I6V A;  1Q6N A;  4B04 A;  2ZMM A;  2CFV A;  1FPZ A;  4AZ1 A;  5KAC A;  2HC2 A;  1Q6M A;  2JJD A;  4QUN A;  4R0S A;  4DGP A;  5KA7 A;  3MOW A;  1QZ0 A;  4GS0 A;  4ICZ A;  4PVG A;  2C7S A;  1PA9 A;  1WCH A;  2IMG A;  3BLT A;  2B4S A;  3GXG A;  2J16 A;  2PBN A;  4KI9 A;  5KA0 A;  1OEV A;  1OEU A;  1OHE A;  4NYH A;  2I6P A;  4RH5 A;  1YTW A;  1PH0 A;  3LJ8 A;  4RHG A;  1C88 A;  2NLK A;  4R30 A;  1XM2 A;  2F6V A;  4GWF A;  1ONZ A;  4NWF A;  3V0G A;  4D3R A;  3H2X A;  2QBQ A;  3ZM0 A;  3ZMP A;  2HNQ A;  2I3U A;  2SHP A;  1A5Y A;  2NT7 A;  1LQF A;  2GP0 A;  1G7F A;  1OES A;  3V0J A;  3BRH A;  3S3F A;  5K23 A;  2FJM A;  3EAX A;  2RF6 A;  3QCD A;  4YAA A;  5K24 A;  2F6T A;  3F9A A;  2CM3 A;  5AWX A;  4OHI A;  4RKK A;  3F81 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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