2ZW3A

Structure of the connexin-26 gap junction channel at 3.5 angstrom resolution
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
216
structure length
201
Chain Sequence
DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell adhesion
molecule keywords Gap junction beta-2 protein
publication title Structure of the connexin 26 gap junction channel at 3.5 A resolution
pubmed doi rcsb
source organism Homo sapiens
total genus 59
structure length 201
sequence length 216
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2008-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00029 Connexin Connexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.80 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) Gap junction channel protein cysteine-rich domain 2zw3A00
2ZW3A
chains in the Genus database with same CATH superfamily
3VA9A 3DA3A 3FNBA 2A2CA 4NV5A 4G75A 2RADA 2BL8A 4O1OA 2QGMA 3I9V1 4GXTA 4PL4A 1YO7A 2A2DA 4DWLA 2V1CC 1TDPA 2V6EA 3P23A 2K19A 2L1LB 2JAEA 2YFAA 2FEFA 3UITA 4YZDA 2HGKA 4YZ9A 2JB2A 3LJ2A 4YZCA 1SJ8A 2XTQA 2BL7A 4G76A 4HEA1 3AJFA 3F4MA 4PL3A 4Z7HA 3IAS1 3LJ0A 4PL5A 4HFVA 4I1TA 3DA4A 4Q9VA 3Q8DA 2CAZB 1JQOA 4AS2A 3LJ1A 3B55A 4AS3A 3KP9A 4O1PA 2KKMA 4JCVE 2E8GA 1U5KA 4OAUC 2RLDA 3FVVA 3IAM1 3L0IA 2JB1A 3FBVA 4OAVB 4U6RA 2FU2A 5LNK1 2FUG1 2F6MB 2P22B 2MJFB 2RIOA 5HGIA 1W3SA 2ETDA 2XTRA 3SDJA 2GSCA 4Z7GA 2ZRRA 2IP6A 2QSBA 2F66B 2JBWA 4NV2A 2QZGA 2YFBA 2JB3A 3DO9A 3JSBA 2ZW3A 2XMXA
chains in the Genus database with same CATH topology
2ZW3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZW3 A; 
#chains in the Genus database with same CATH topology
 3VA9 A;  3DA3 A;  3FNB A;  2A2C A;  4NV5 A;  4G75 A;  2RAD A;  2BL8 A;  4O1O A;  2QGM A;  3I9V 1;  4GXT A;  4PL4 A;  1YO7 A;  2A2D A;  4DWL A;  2V1C C;  1TDP A;  2V6E A;  3P23 A;  2K19 A;  2L1L B;  2JAE A;  2YFA A;  2FEF A;  3UIT A;  4YZD A;  2HGK A;  4YZ9 A;  2JB2 A;  3LJ2 A;  4YZC A;  1SJ8 A;  2XTQ A;  2BL7 A;  4G76 A;  4HEA 1;  3AJF A;  3F4M A;  4PL3 A;  4Z7H A;  3IAS 1;  3LJ0 A;  4PL5 A;  4HFV A;  4I1T A;  3DA4 A;  4Q9V A;  3Q8D A;  2CAZ B;  1JQO A;  4AS2 A;  3LJ1 A;  3B55 A;  4AS3 A;  3KP9 A;  4O1P A;  2KKM A;  4JCV E;  2E8G A;  1U5K A;  4OAU C;  2RLD A;  3FVV A;  3IAM 1;  3L0I A;  2JB1 A;  3FBV A;  4OAV B;  4U6R A;  2FU2 A;  5LNK 1;  2FUG 1;  2F6M B;  2P22 B;  2MJF B;  2RIO A;  5HGI A;  1W3S A;  2ETD A;  2XTR A;  3SDJ A;  2GSC A;  4Z7G A;  2ZRR A;  2IP6 A;  2QSB A;  2F66 B;  2JBW A;  4NV2 A;  2QZG A;  2YFB A;  2JB3 A;  3DO9 A;  3JSB A;  2ZW3 A;  2XMX A; 
#chains in the Genus database with same CATH homology
 2ZW3 A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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