2ZWEB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 40 minutes
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
84
structure length
77
Chain Sequence
AAPESFDEVYKGRRIQGRPAHEHGGGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/metal transport
molecule keywords Tyrosinase
publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
source organism Streptomyces castaneoglobisporus
total genus 16
structure length 77
sequence length 84
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zweB01
1WX5B 1WXCB 3AWXB 2AHLB 2ZMXB 2JV8A 2AHKB 3AWUB 2ZWEB 3AWYB 3AX0B 1WX4B 2ZMYB 2ZWDB 1WX2B 2ZWGB 2ZMZB 2ZWFB 3AWSB 3AWWB 3AWTB 3AWZB 3AWVB
chains in the Genus database with same CATH superfamily
1Z02A 4NBGA 1WX5B 2ZMXB 1WXCB 2AHLB 3AWXB 2JV8A 4NBHA 2AHKB 3GCFA 3AWUB 2ZWEB 4NBEA 3AWYB 3AX0B 4NB8A 2DE5A 1WX4B 1Z03A 2ZWDB 1WX2B 2ZMYB 2ZWGB 2ZMZB 2ZWFB 4NBBA 4NBDA 3VMIA 1Z01A 4NBCA 4NBAA 3AWSB 3AWWB 2DE7A 3VMGA 3AWTB 4NB9A 1WW9A 4NBFA 3GKQA 3VMHA 2DE6A 3AWZB 3AWVB
chains in the Genus database with same CATH topology
1WX5B 1WXCB 3AWXB 2AHLB 2ZMXB 2JV8A 2AHKB 3AWUB 2ZWEB 3AWYB 3AX0B 1WX4B 2ZMYB 2ZWDB 1WX2B 2ZWGB 2ZMZB 2ZWFB 3AWSB 3AWWB 3AWTB 3AWZB 3AWVB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WX5 B;  1WXC B;  3AWX B;  2AHL B;  2ZMX B;  2JV8 A;  2AHK B;  3AWU B;  2ZWE B;  3AWY B;  3AX0 B;  1WX4 B;  2ZMY B;  2ZWD B;  1WX2 B;  2ZWG B;  2ZMZ B;  2ZWF B;  3AWS B;  3AWW B;  3AWT B;  3AWZ B;  3AWV B; 
#chains in the Genus database with same CATH topology
 1Z02 A;  4NBG A;  1WX5 B;  2ZMX B;  1WXC B;  2AHL B;  3AWX B;  2JV8 A;  4NBH A;  2AHK B;  3GCF A;  3AWU B;  2ZWE B;  4NBE A;  3AWY B;  3AX0 B;  4NB8 A;  2DE5 A;  1WX4 B;  1Z03 A;  2ZWD B;  1WX2 B;  2ZMY B;  2ZWG B;  2ZMZ B;  2ZWF B;  4NBB A;  4NBD A;  3VMI A;  1Z01 A;  4NBC A;  4NBA A;  3AWS B;  3AWW B;  2DE7 A;  3VMG A;  3AWT B;  4NB9 A;  1WW9 A;  4NBF A;  3GKQ A;  3VMH A;  2DE6 A;  3AWZ B;  3AWV B; 
#chains in the Genus database with same CATH homology
 1WX5 B;  1WXC B;  3AWX B;  2AHL B;  2ZMX B;  2JV8 A;  2AHK B;  3AWU B;  2ZWE B;  3AWY B;  3AX0 B;  1WX4 B;  2ZMY B;  2ZWD B;  1WX2 B;  2ZWG B;  2ZMZ B;  2ZWF B;  3AWS B;  3AWW B;  3AWT B;  3AWZ B;  3AWV B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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