2ZWEB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 40 minutes
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
84
structure length
77
Chain Sequence
AAPESFDEVYKGRRIQGRPAHEHGGGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
molecule keywords Tyrosinase
total genus 16
structure length 77
sequence length 84
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zweB01
2ZMYB 2JV8A 2ZWEB 2AHKB 3AWYB 3AWSB 2ZMZB 2AHLB 3AWVB 3AWUB 1WX4B 3AWTB 3AWWB 1WX5B 2ZWGB 1WXCB 2ZWDB 2ZMXB 2ZWFB 3AWZB 1WX2B 3AX0B 3AWXB
chains in the Genus database with same CATH superfamily
2ZMYB 3AWXB 4NB9A 4NBHA 2JV8A 2ZWEB 2AHKB 3AWYB 3AWSB 4NBEA 2ZMZB 2AHLB 3AWVB 3AWUB 4NBCA 1WX4B 3AWTB 4NBFA 3AWWB 4NBAA 4NBGA 1WX5B 3GCFA 2ZWGB 4NBDA 1WXCB 3VMGA 2ZWDB 3GKQA 2ZMXB 2ZWFB 1WW9A 1Z01A 2DE5A 3VMHA 3AWZB 1Z02A 1WX2B 4NB8A 2DE6A 4NBBA 3VMIA 1Z03A 3AX0B 2DE7A
chains in the Genus database with same CATH topology
2ZMYB 2JV8A 2ZWEB 2AHKB 3AWYB 3AWSB 2ZMZB 2AHLB 3AWVB 3AWUB 1WX4B 3AWTB 3AWWB 1WX5B 2ZWGB 1WXCB 2ZWDB 2ZMXB 2ZWFB 3AWZB 1WX2B 3AX0B 3AWXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZMY B;  2JV8 A;  2ZWE B;  2AHK B;  3AWY B;  3AWS B;  2ZMZ B;  2AHL B;  3AWV B;  3AWU B;  1WX4 B;  3AWT B;  3AWW B;  1WX5 B;  2ZWG B;  1WXC B;  2ZWD B;  2ZMX B;  2ZWF B;  3AWZ B;  1WX2 B;  3AX0 B;  3AWX B; 
#chains in the Genus database with same CATH topology
 2ZMY B;  3AWX B;  4NB9 A;  4NBH A;  2JV8 A;  2ZWE B;  2AHK B;  3AWY B;  3AWS B;  4NBE A;  2ZMZ B;  2AHL B;  3AWV B;  3AWU B;  4NBC A;  1WX4 B;  3AWT B;  4NBF A;  3AWW B;  4NBA A;  4NBG A;  1WX5 B;  3GCF A;  2ZWG B;  4NBD A;  1WXC B;  3VMG A;  2ZWD B;  3GKQ A;  2ZMX B;  2ZWF B;  1WW9 A;  1Z01 A;  2DE5 A;  3VMH A;  3AWZ B;  1Z02 A;  1WX2 B;  4NB8 A;  2DE6 A;  4NBB A;  3VMI A;  1Z03 A;  3AX0 B;  2DE7 A; 
#chains in the Genus database with same CATH homology
 2ZMY B;  2JV8 A;  2ZWE B;  2AHK B;  3AWY B;  3AWS B;  2ZMZ B;  2AHL B;  3AWV B;  3AWU B;  1WX4 B;  3AWT B;  3AWW B;  1WX5 B;  2ZWG B;  1WXC B;  2ZWD B;  2ZMX B;  2ZWF B;  3AWZ B;  1WX2 B;  3AX0 B;  3AWX B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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