2ZWFB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 80 minutes
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
83
structure length
71
Chain Sequence
AAPESFDEVYKGRRIQGRPAGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule keywords Tyrosinase
total genus 15
structure length 71
sequence length 83
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zwfB01
1WX2B 2ZMYB 3AWVB 1WX4B 2ZWDB 2JV8A 1WX5B 2ZWFB 2ZMZB 2AHLB 3AWWB 2ZWEB 3AWYB 3AWZB 3AWXB 3AX0B 3AWUB 3AWSB 3AWTB 2ZWGB 2AHKB 1WXCB 2ZMXB
chains in the Genus database with same CATH superfamily
2DE5A 1WX2B 4NB8A 4NBEA 2ZMYB 2DE6A 3GCFA 4NBBA 3AWVB 4NBGA 4NBFA 1WX4B 2ZWDB 2JV8A 1WX5B 3VMIA 3VMGA 3VMHA 2ZWFB 4NBAA 2ZMZB 1Z01A 1Z02A 2AHLB 3AWWB 2ZWEB 3AWYB 3AWZB 4NBCA 4NBDA 3AWXB 3AX0B 3AWUB 1WW9A 3AWSB 3GKQA 3AWTB 4NB9A 2ZWGB 2DE7A 1Z03A 2AHKB 1WXCB 4NBHA 2ZMXB
chains in the Genus database with same CATH topology
1WX2B 2ZMYB 3AWVB 1WX4B 2ZWDB 2JV8A 1WX5B 2ZWFB 2ZMZB 2AHLB 3AWWB 2ZWEB 3AWYB 3AWZB 3AWXB 3AX0B 3AWUB 3AWSB 3AWTB 2ZWGB 2AHKB 1WXCB 2ZMXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WX2 B;  2ZMY B;  3AWV B;  1WX4 B;  2ZWD B;  2JV8 A;  1WX5 B;  2ZWF B;  2ZMZ B;  2AHL B;  3AWW B;  2ZWE B;  3AWY B;  3AWZ B;  3AWX B;  3AX0 B;  3AWU B;  3AWS B;  3AWT B;  2ZWG B;  2AHK B;  1WXC B;  2ZMX B; 
#chains in the Genus database with same CATH topology
 2DE5 A;  1WX2 B;  4NB8 A;  4NBE A;  2ZMY B;  2DE6 A;  3GCF A;  4NBB A;  3AWV B;  4NBG A;  4NBF A;  1WX4 B;  2ZWD B;  2JV8 A;  1WX5 B;  3VMI A;  3VMG A;  3VMH A;  2ZWF B;  4NBA A;  2ZMZ B;  1Z01 A;  1Z02 A;  2AHL B;  3AWW B;  2ZWE B;  3AWY B;  3AWZ B;  4NBC A;  4NBD A;  3AWX B;  3AX0 B;  3AWU B;  1WW9 A;  3AWS B;  3GKQ A;  3AWT B;  4NB9 A;  2ZWG B;  2DE7 A;  1Z03 A;  2AHK B;  1WXC B;  4NBH A;  2ZMX B; 
#chains in the Genus database with same CATH homology
 1WX2 B;  2ZMY B;  3AWV B;  1WX4 B;  2ZWD B;  2JV8 A;  1WX5 B;  2ZWF B;  2ZMZ B;  2AHL B;  3AWW B;  2ZWE B;  3AWY B;  3AWZ B;  3AWX B;  3AX0 B;  3AWU B;  3AWS B;  3AWT B;  2ZWG B;  2AHK B;  1WXC B;  2ZMX B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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