2ZWGB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 12 hours
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
83
structure length
71
Chain Sequence
AAPESFDEVYKGRRIQGRPAGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/metal transport
molecule keywords Tyrosinase
publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
source organism Streptomyces castaneoglobisporus
total genus 16
structure length 71
sequence length 83
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zwgB01
2ZWFB 3AWXB 3AWYB 2ZMXB 2AHLB 1WXCB 3AWZB 2ZWGB 3AWWB 2ZWDB 3AWVB 3AWTB 3AWSB 2JV8A 2AHKB 1WX4B 3AX0B 2ZMZB 2ZWEB 1WX2B 2ZMYB 1WX5B 3AWUB
chains in the Genus database with same CATH superfamily
2ZWFB 3VMGA 4NBGA 3AWXB 4NB8A 3AWYB 2ZMXB 2AHLB 1WXCB 4NBFA 1WW9A 1Z03A 3AWZB 4NBCA 4NB9A 2DE7A 2ZWGB 4NBBA 4NBEA 3AWWB 4NBHA 2ZWDB 3VMHA 3AWVB 2DE6A 3VMIA 3AWTB 3AWSB 2JV8A 2AHKB 3GKQA 3GCFA 1WX4B 2DE5A 2ZMZB 3AX0B 2ZWEB 1Z02A 1WX2B 2ZMYB 1WX5B 3AWUB 4NBDA 1Z01A 4NBAA
chains in the Genus database with same CATH topology
2ZWFB 3AWXB 3AWYB 2ZMXB 2AHLB 1WXCB 3AWZB 2ZWGB 3AWWB 2ZWDB 3AWVB 3AWTB 3AWSB 2JV8A 2AHKB 1WX4B 3AX0B 2ZMZB 2ZWEB 1WX2B 2ZMYB 1WX5B 3AWUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZWF B;  3AWX B;  3AWY B;  2ZMX B;  2AHL B;  1WXC B;  3AWZ B;  2ZWG B;  3AWW B;  2ZWD B;  3AWV B;  3AWT B;  3AWS B;  2JV8 A;  2AHK B;  1WX4 B;  3AX0 B;  2ZMZ B;  2ZWE B;  1WX2 B;  2ZMY B;  1WX5 B;  3AWU B; 
#chains in the Genus database with same CATH topology
 2ZWF B;  3VMG A;  4NBG A;  3AWX B;  4NB8 A;  3AWY B;  2ZMX B;  2AHL B;  1WXC B;  4NBF A;  1WW9 A;  1Z03 A;  3AWZ B;  4NBC A;  4NB9 A;  2DE7 A;  2ZWG B;  4NBB A;  4NBE A;  3AWW B;  4NBH A;  2ZWD B;  3VMH A;  3AWV B;  2DE6 A;  3VMI A;  3AWT B;  3AWS B;  2JV8 A;  2AHK B;  3GKQ A;  3GCF A;  1WX4 B;  2DE5 A;  2ZMZ B;  3AX0 B;  2ZWE B;  1Z02 A;  1WX2 B;  2ZMY B;  1WX5 B;  3AWU B;  4NBD A;  1Z01 A;  4NBA A; 
#chains in the Genus database with same CATH homology
 2ZWF B;  3AWX B;  3AWY B;  2ZMX B;  2AHL B;  1WXC B;  3AWZ B;  2ZWG B;  3AWW B;  2ZWD B;  3AWV B;  3AWT B;  3AWS B;  2JV8 A;  2AHK B;  1WX4 B;  3AX0 B;  2ZMZ B;  2ZWE B;  1WX2 B;  2ZMY B;  1WX5 B;  3AWU B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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