2ZZDB

Recombinant thiocyanate hydrolase, air-oxidized form of holo-enzyme
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
153
structure length
153
Chain Sequence
SSIREEVHRHLGTVALMQPALHQQTHAPAPTEITHTLFRAYTRVPHDVGGEADVPIEYHEKEEEIWELNTFATCECLAWRGVWTAEERRRKQNCDVGQTVYLGMPYYGRWLLTAARILVDKQFVTLTELHNKIVEMRERVASGQGLGEYLPPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification
pubmed doi rcsb
molecule tags Hydrolase
source organism Thiobacillus thioparus
molecule keywords Thiocyanate hydrolase subunit alpha
total genus 46
structure length 153
sequence length 153
chains with identical sequence E, H, K
ec nomenclature ec 3.5.5.8: Thiocyanate hydrolase.
pdb deposition date 2009-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02211 NHase_beta Nitrile hydratase beta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.20 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2zzdB00
4OB1B 3QYHB 1UGSB 3QYGB 3A8GB 3QXEB 4OB0B 2ZPBB 3A8MB 3QZ9B 3VYHB 1UGPB 1AHJB 3X26B 2CZ1B 3WVDB 2DPPB 2ZPHB 3X24B 2DXCB 2ZCFB 2ZPFB 1UGQB 2CZ6B 1IREB 4ZGJB 1V29B 2QDYB 3QZ5B 2AHJB 3X20B 3X28B 3WVEB 4ZGDB 2CYZB 3A8HB 4FM4B 2ZPEB 2DD4B 2ZPGB 4OB2B 3X25B 3A8OB 1UGRB 2ZPIB 4ZGEB 3HHTB 2DXBB 3A8LB 2D0QB 4OB3B 3VYGB 2CZ0B 2DD5B 2CZ7B 2ZZDB
chains in the Genus database with same CATH superfamily
4OB0B 2W2HA 2QF7A 2G9XB 5CYIB 2WPAB 2DXCB 3MY5B 3TN8B 3A8HB 4BBRM 3B57A 4OGRB 5FGKB 1N4MA 2WIHB 2ZPBB 3BHUB 1UGPB 3QHRB 2W99A 4EOQB 5IF1B 4II5B 1AISB 2PK2A 4IMYB 1XO2A 1FKMA 4BCQD 4YC3B 4BCQB 4CFXB 4BCOB 1H27B 4F6WB 4RODA 3BG5A 1BU2A 2DD5B 4NC6A 3TW6A 3QYHB 2DMEA 3HB9A 4EOKB 2IN3A 4BCHB 2UZLB 4EOJB 1VOLA 4EOIB 4YOSA 2ZPGB 2ZPIB 4HNVA 1OL1B 3BLQB 3DJBA 3NDQA 4BCPB 2UZEB 2WHBB 1OKVB 1H1QB 2KR6A 4EOLB 4EONB 2QDYB 3DOGB 5DQVA 4QSHA 3F5XB 1H1SB 1TD6A 2WMAB 2CCIB 4G6LB 3BLRB 4BXXX 3QWLA 2C5VB 4KRDB 1G3NC 2BS3A 3VKGA 1PKDB 3X26B 3LQ5B 1JOWA 1UGQB 4EORB 2PK9B 1UNGD 2CYZB 5IDPB 1H1PB 1FINB 5HBEB 4BCMD 1P5EB 3MIAB 4BCMB 4AKIA 5ACBA 3DDPB 1UGSB 4HNTA 4F7JB 1QLBA 5ICPB 2I40B 4HLQA 2C5OB 1TFBA 3G33B 3X24B 3BG9A 2DD4B 3X25B 3A8OB 4I3ZB 5I5ZB 4AKGA 5BNJB 4BCND 4BCNB 3BHTB 4BCGB 1OIUB 2PJQA 1UNHD 3O0GD 3QZ9B 3QYEA 1VINA 2CZ1B 4AI6A 1D3UB 2WFYB 4BCIB 2ZPHB 3QYBA 4MFEA 1OGUB 2BPMB 3BG3A 1JSTB 4MIMA 2WIPB 2WMBB 4OB1B 4Y72B 4EC8B 3A8GB 3QXEB 4EC9B 4FX3B 1H25B 3X20B 4CFWB 2B9RA 3X28B 2EUFA 2F2CA 4EOSB 1OL2B 5EFQB 4F6SB 2UZDB 4BY1X 2DXBB 1AD6A 3VYGB 4ROEA 1H28B 2ZZDB 5HNBB 4NSTB 4JX5A 2CCHB 3WVDB 4AKHA 3TNIB 5LQFB 1OI9B 1C9BA 1KXUA 3A8LB 2R7GA 3EJ1B 4YOOA 3HZJA 1QMZB 4CFNB 3BHVB 2W9ZA 3RGFB 1GY3B 4EOOB 4JX4A 2G77A 2C6TB 4F7SB 2X1NB 3K7AM 4KRCB 3QZ5B 4Z6YA 1GUXB 1UGRB 5L2WB 1VYWB 3HHTB 1W98B 4BBSM 1H1RB 3QYGB 2C5XB 4EOMB 3H4CA 2V22B 4BCKB 1ENWA 3MI9B 2ZPFB 3DL1A 2C5NB 3MY1B 4CXAB 2ZPEB 2IW9B 3PO3S 2UUEB 1GUXA 2QQ8A 2WJ9A 2D0QB 2BS2A 3KHIA 4BCJB 2CZ7B 3VKHA 5IHYA 1E7PA 3A8MB 3VYHB 1F5QB 1UNLD 5HBHB 3TW7A 2CZ6B 2W9FA 3HO8A 4ZGDB 4JX6A 4M6VA 1E9HB 2LW4A 3HBLA 2PHGA 1FVVB 1ZP2A 2QFZA 1AHJB 2BKZB 5CEIB 4TTHA 4F70B 2DPPB 2WXVB 4F6UB 3EOCB 1O9KB 1H24B 1V29B 2AHJB 4F7LB 4OB2B 2PMIB 5IDNB 3BLHB 3M03A 4ZGEB 4OR5B 5HBJB 4CFUD 3EIDB 4CFUB 2IVXA 2QGSA 4CFMB 3DDQB 4UN0A 1O9KA 3DTOA 5DQWA 2QDJA 4FM4B 1JKWA 2WEVB 4EOPB 3QHWB 4OB3B 2IW6B 2CJMB 4MFDA 4YOZA 3TNWB 2IW8B 4CFVB 4ROCA 2C4GB 4LOCA 4CRLB 2I53A 4HNUA 1IREB 2KMGA 4ELLA 1GH6B 1OKWB 2CZ0B 5HQ0B 1URCB 4BCFB 4F7NB 2BS4A 4ELJA 1H4LD 3POMA 1JSUB 1OIYB 2ZCFB 4ZGJB 5EJCA 3WVEB 4HL4A 5LMKB 2W96A 1H26B 3GTMS 2JGZB 4BY7X 2UZBB 3TNHB 5HVYB
chains in the Genus database with same CATH topology
4JX5A 3QWLA 4OB0B 2BS3A 3VKGA 2QFZA 1AHJB 2QF7A 3X26B 3WVDB 4AKHA 2DPPB 2DXCB 1UGQB 1V29B 2AHJB 2CYZB 3A8HB 4BBRM 4OB2B 4ZGEB 3A8LB 4AKIA 3HZJA 1UGSB 2ZPBB 4HNTA 1QLBA 1UGPB 4JX4A 4HLQA 2G77A 3X24B 3BG9A 3QZ5B 1FKMA 2QDJA 4FM4B 4Z6YA 2DD4B 3X25B 3A8OB 1UGRB 4AKGA 3HHTB 3BG5A 4OB3B 4MFDA 2DD5B 4NC6A 4BBSM 3TW6A 3QYHB 3HB9A 3QYGB 3QZ9B 3QYEA 3H4CA 4LOCA 2CZ1B 4AI6A 2ZPHB 2ZPFB 4HNUA 3QYBA 3DL1A 1IREB 4MFEA 2KMGA 2ZPEB 2ZPGB 2ZPIB 3BG3A 4HNVA 2QQ8A 2WJ9A 4MIMA 2D0QB 2BS2A 2CZ0B 3KHIA 2CZ7B 3VKHA 4OB1B 3A8GB 2BS4A 3QXEB 1E7PA 3A8MB 3VYHB 4ELJA 2KR6A 2ZCFB 3TW7A 2CZ6B 4ZGJB 2QDYB 3HO8A 3X20B 5EJCA 3X28B 4QSHA 3WVEB 4ZGDB 4HL4A 4JX6A 4M6VA 2DXBB 3VYGB 3HBLA 2ZZDB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OB1 B;  3QYH B;  1UGS B;  3QYG B;  3A8G B;  3QXE B;  4OB0 B;  2ZPB B;  3A8M B;  3QZ9 B;  3VYH B;  1UGP B;  1AHJ B;  3X26 B;  2CZ1 B;  3WVD B;  2DPP B;  2ZPH B;  3X24 B;  2DXC B;  2ZCF B;  2ZPF B;  1UGQ B;  2CZ6 B;  1IRE B;  4ZGJ B;  1V29 B;  2QDY B;  3QZ5 B;  2AHJ B;  3X20 B;  3X28 B;  3WVE B;  4ZGD B;  2CYZ B;  3A8H B;  4FM4 B;  2ZPE B;  2DD4 B;  2ZPG B;  4OB2 B;  3X25 B;  3A8O B;  1UGR B;  2ZPI B;  4ZGE B;  3HHT B;  2DXB B;  3A8L B;  2D0Q B;  4OB3 B;  3VYG B;  2CZ0 B;  2DD5 B;  2CZ7 B;  2ZZD B; 
#chains in the Genus database with same CATH topology
 4OB0 B;  2W2H A;  2QF7 A;  2G9X B;  5CYI B;  2WPA B;  2DXC B;  3MY5 B;  3TN8 B;  3A8H B;  4BBR M;  3B57 A;  4OGR B;  5FGK B;  1N4M A;  2WIH B;  2ZPB B;  3BHU B;  1UGP B;  3QHR B;  2W99 A;  4EOQ B;  5IF1 B;  4II5 B;  1AIS B;  2PK2 A;  4IMY B;  1XO2 A;  1FKM A;  4BCQ D;  4YC3 B;  4BCQ B;  4CFX B;  4BCO B;  1H27 B;  4F6W B;  4ROD A;  3BG5 A;  1BU2 A;  2DD5 B;  4NC6 A;  3TW6 A;  3QYH B;  2DME A;  3HB9 A;  4EOK B;  2IN3 A;  4BCH B;  2UZL B;  4EOJ B;  1VOL A;  4EOI B;  4YOS A;  2ZPG B;  2ZPI B;  4HNV A;  1OL1 B;  3BLQ B;  3DJB A;  3NDQ A;  4BCP B;  2UZE B;  2WHB B;  1OKV B;  1H1Q B;  2KR6 A;  4EOL B;  4EON B;  2QDY B;  3DOG B;  5DQV A;  4QSH A;  3F5X B;  1H1S B;  1TD6 A;  2WMA B;  2CCI B;  4G6L B;  3BLR B;  4BXX X;  3QWL A;  2C5V B;  4KRD B;  1G3N C;  2BS3 A;  3VKG A;  1PKD B;  3X26 B;  3LQ5 B;  1JOW A;  1UGQ B;  4EOR B;  2PK9 B;  1UNG D;  2CYZ B;  5IDP B;  1H1P B;  1FIN B;  5HBE B;  4BCM D;  1P5E B;  3MIA B;  4BCM B;  4AKI A;  5ACB A;  3DDP B;  1UGS B;  4HNT A;  4F7J B;  1QLB A;  5ICP B;  2I40 B;  4HLQ A;  2C5O B;  1TFB A;  3G33 B;  3X24 B;  3BG9 A;  2DD4 B;  3X25 B;  3A8O B;  4I3Z B;  5I5Z B;  4AKG A;  5BNJ B;  4BCN D;  4BCN B;  3BHT B;  4BCG B;  1OIU B;  2PJQ A;  1UNH D;  3O0G D;  3QZ9 B;  3QYE A;  1VIN A;  2CZ1 B;  4AI6 A;  1D3U B;  2WFY B;  4BCI B;  2ZPH B;  3QYB A;  4MFE A;  1OGU B;  2BPM B;  3BG3 A;  1JST B;  4MIM A;  2WIP B;  2WMB B;  4OB1 B;  4Y72 B;  4EC8 B;  3A8G B;  3QXE B;  4EC9 B;  4FX3 B;  1H25 B;  3X20 B;  4CFW B;  2B9R A;  3X28 B;  2EUF A;  2F2C A;  4EOS B;  1OL2 B;  5EFQ B;  4F6S B;  2UZD B;  4BY1 X;  2DXB B;  1AD6 A;  3VYG B;  4ROE A;  1H28 B;  2ZZD B;  5HNB B;  4NST B;  4JX5 A;  2CCH B;  3WVD B;  4AKH A;  3TNI B;  5LQF B;  1OI9 B;  1C9B A;  1KXU A;  3A8L B;  2R7G A;  3EJ1 B;  4YOO A;  3HZJ A;  1QMZ B;  4CFN B;  3BHV B;  2W9Z A;  3RGF B;  1GY3 B;  4EOO B;  4JX4 A;  2G77 A;  2C6T B;  4F7S B;  2X1N B;  3K7A M;  4KRC B;  3QZ5 B;  4Z6Y A;  1GUX B;  1UGR B;  5L2W B;  1VYW B;  3HHT B;  1W98 B;  4BBS M;  1H1R B;  3QYG B;  2C5X B;  4EOM B;  3H4C A;  2V22 B;  4BCK B;  1ENW A;  3MI9 B;  2ZPF B;  3DL1 A;  2C5N B;  3MY1 B;  4CXA B;  2ZPE B;  2IW9 B;  3PO3 S;  2UUE B;  1GUX A;  2QQ8 A;  2WJ9 A;  2D0Q B;  2BS2 A;  3KHI A;  4BCJ B;  2CZ7 B;  3VKH A;  5IHY A;  1E7P A;  3A8M B;  3VYH B;  1F5Q B;  1UNL D;  5HBH B;  3TW7 A;  2CZ6 B;  2W9F A;  3HO8 A;  4ZGD B;  4JX6 A;  4M6V A;  1E9H B;  2LW4 A;  3HBL A;  2PHG A;  1FVV B;  1ZP2 A;  2QFZ A;  1AHJ B;  2BKZ B;  5CEI B;  4TTH A;  4F70 B;  2DPP B;  2WXV B;  4F6U B;  3EOC B;  1O9K B;  1H24 B;  1V29 B;  2AHJ B;  4F7L B;  4OB2 B;  2PMI B;  5IDN B;  3BLH B;  3M03 A;  4ZGE B;  4OR5 B;  5HBJ B;  4CFU D;  3EID B;  4CFU B;  2IVX A;  2QGS A;  4CFM B;  3DDQ B;  4UN0 A;  1O9K A;  3DTO A;  5DQW A;  2QDJ A;  4FM4 B;  1JKW A;  2WEV B;  4EOP B;  3QHW B;  4OB3 B;  2IW6 B;  2CJM B;  4MFD A;  4YOZ A;  3TNW B;  2IW8 B;  4CFV B;  4ROC A;  2C4G B;  4LOC A;  4CRL B;  2I53 A;  4HNU A;  1IRE B;  2KMG A;  4ELL A;  1GH6 B;  1OKW B;  2CZ0 B;  5HQ0 B;  1URC B;  4BCF B;  4F7N B;  2BS4 A;  4ELJ A;  1H4L D;  3POM A;  1JSU B;  1OIY B;  2ZCF B;  4ZGJ B;  5EJC A;  3WVE B;  4HL4 A;  5LMK B;  2W96 A;  1H26 B;  3GTM S;  2JGZ B;  4BY7 X;  2UZB B;  3TNH B;  5HVY B; 
#chains in the Genus database with same CATH homology
 4JX5 A;  3QWL A;  4OB0 B;  2BS3 A;  3VKG A;  2QFZ A;  1AHJ B;  2QF7 A;  3X26 B;  3WVD B;  4AKH A;  2DPP B;  2DXC B;  1UGQ B;  1V29 B;  2AHJ B;  2CYZ B;  3A8H B;  4BBR M;  4OB2 B;  4ZGE B;  3A8L B;  4AKI A;  3HZJ A;  1UGS B;  2ZPB B;  4HNT A;  1QLB A;  1UGP B;  4JX4 A;  4HLQ A;  2G77 A;  3X24 B;  3BG9 A;  3QZ5 B;  1FKM A;  2QDJ A;  4FM4 B;  4Z6Y A;  2DD4 B;  3X25 B;  3A8O B;  1UGR B;  4AKG A;  3HHT B;  3BG5 A;  4OB3 B;  4MFD A;  2DD5 B;  4NC6 A;  4BBS M;  3TW6 A;  3QYH B;  3HB9 A;  3QYG B;  3QZ9 B;  3QYE A;  3H4C A;  4LOC A;  2CZ1 B;  4AI6 A;  2ZPH B;  2ZPF B;  4HNU A;  3QYB A;  3DL1 A;  1IRE B;  4MFE A;  2KMG A;  2ZPE B;  2ZPG B;  2ZPI B;  3BG3 A;  4HNV A;  2QQ8 A;  2WJ9 A;  4MIM A;  2D0Q B;  2BS2 A;  2CZ0 B;  3KHI A;  2CZ7 B;  3VKH A;  4OB1 B;  3A8G B;  2BS4 A;  3QXE B;  1E7P A;  3A8M B;  3VYH B;  4ELJ A;  2KR6 A;  2ZCF B;  3TW7 A;  2CZ6 B;  4ZGJ B;  2QDY B;  3HO8 A;  3X20 B;  5EJC A;  3X28 B;  4QSH A;  3WVE B;  4ZGD B;  4HL4 A;  4JX6 A;  4M6V A;  2DXB B;  3VYG B;  3HBL A;  2ZZD B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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