2AAFA

Structure of h278a arginine deiminase with l-arginine forming a s-alkylthiouronium reaction intermediate
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
412
structure length
404
Chain Sequence
TKLGVHSEAGKLRKVMVCSPGLAHQRLTPSNCDELLFDDVIWVNQAKRDHFDFVTKMRERGIDVLEMHNLLTETIQNPEALKWILDRKITADSVGLGLTSELRSWLESLEPRKLAEYLIGGVAADDLPASEGANILKMYREYLGHSSFLLPPLPNTQFTRDTTCWIYGGVTLNPMYWPARRQETLLTTAIYKFHPEFANAEFEIWYGDPDKDHGSSTLEGGDVMPIGNGVVLIGMGERSSRQAIGQVAQSLFAKGAAERVIVAGLPKSRAAMALDTVFSFCDRDLVTVFPEVVKEIVPFSLRPDPSSPYGMNIRREEKTFLEVVAESLGLKKLRVVETGREQWDDGNNVVCLEPGVVVGYDRNTYTNTLLRKAGVEVITISASELGRGRGGGHMTCPIVRDPID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures Representing the Michaelis Complex and the Thiouronium Reaction Intermediate of Pseudomonas aeruginosa Arginine Deiminase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Pseudomonas aeruginosa
molecule keywords Arginine deiminase
total genus 135
structure length 404
sequence length 412
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.6: Arginine deiminase.
pdb deposition date 2005-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3930.10 Mainly Alpha Orthogonal Bundle Pentein Arginine deiminase 2aafA02
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2aafA01
1LXYA 1WD8A 2DEWX 8JDWA 1G61A 4YTGA 2JAJA 9JDWA 7JDWA 4N2NA 1H70A 3I2EA 2JDWA 2Q3UA 4YT9A 4N26A 3JDWA 1ZBRA 2CI7A 1S9RA 4X8GA 2DEYX 1G62A 4N2AA 1JDXA 4X8CA 4N25A 4N2BA 4N2LA 3APNA 4YTBA 4N2DA 5JDWA 2EWOA 1VKPA 4N2KA 4DKTA 6JDWA 3P8PA 2C6ZA 1RXXA 4N2CA 4N2EA 4BOFA 4N28A 5AN9I 4E4JA 4N2MA 3H7KA 5HP5A 2CI5A 5AK7A 3HVMA 2JERA 4N2FA 3I4AA 2CI3A 3B1TA 4N22A 1WDAA 3B1UA 4N20A 1WD9A 3APMA 5AK8A 2CMUA 2CI4A 4N2HA 1BWDA 3P8EA 4JDWA 3H7CX 3RHYA 2AAFA 2DEXX 4N24A 2ABRA 1XKNA 2JDXA 1JDWA 4N2IA 4N2GA 5M3QA 2A9GA 2DW5A 2JAIA 2ACIA 2CI6A 3BPBA 2CI1A
chains in the Genus database with same CATH superfamily
1LXYA 1WD8A 2DEWX 8JDWA 1G61A 4YTGA 2JAJA 9JDWA 7JDWA 4N2NA 1H70A 3I2EA 2JDWA 2Q3UA 4YT9A 4N26A 3JDWA 1ZBRA 2CI7A 1S9RA 4X8GA 2DEYX 1G62A 4N2AA 1JDXA 4X8CA 4N25A 4N2BA 4N2LA 3APNA 4YTBA 4N2DA 5JDWA 2EWOA 1VKPA 4N2KA 1YNIA 4DKTA 6JDWA 3P8PA 2C6ZA 1RXXA 4N2CA 4N2EA 4BOFA 4N28A 5AN9I 4E4JA 4N2MA 3H7KA 5HP5A 2CI5A 5AK7A 3HVMA 2JERA 4N2FA 3I4AA 2CI3A 3B1TA 4N22A 1WDAA 3B1UA 4N20A 1WD9A 3APMA 5AK8A 2CMUA 2CI4A 4N2HA 1BWDA 1YNHA 3P8EA 4JDWA 3H7CX 3RHYA 2AAFA 2DEXX 4N24A 2ABRA 1XKNA 1YNFA 2JDXA 1JDWA 4N2IA 4N2GA 5M3QA 2A9GA 2DW5A 2JAIA 2ACIA 2CI6A 3BPBA 2CI1A
chains in the Genus database with same CATH topology
1LXYA 1WD8A 2DEWX 8JDWA 1G61A 4YTGA 2JAJA 9JDWA 7JDWA 4N2NA 1H70A 3I2EA 2JDWA 2Q3UA 4YT9A 4N26A 3JDWA 1ZBRA 2CI7A 1S9RA 4X8GA 2DEYX 1G62A 4N2AA 1JDXA 4X8CA 4N25A 4N2BA 4N2LA 3APNA 4YTBA 4N2DA 5JDWA 2EWOA 1VKPA 4N2KA 4DKTA 6JDWA 3P8PA 2C6ZA 1RXXA 4N2CA 4N2EA 4BOFA 4N28A 5AN9I 4E4JA 4N2MA 3H7KA 5HP5A 2CI5A 5AK7A 3HVMA 2JERA 4N2FA 3I4AA 2CI3A 3B1TA 4N22A 1WDAA 3B1UA 4N20A 1WD9A 3APMA 5AK8A 2CMUA 2CI4A 4N2HA 1BWDA 3P8EA 4JDWA 3H7CX 3RHYA 2AAFA 2DEXX 4N24A 2ABRA 1XKNA 2JDXA 1JDWA 4N2IA 4N2GA 5M3QA 2A9GA 2DW5A 2JAIA 2ACIA 2CI6A 3BPBA 2CI1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LXY A;  1WD8 A;  2DEW X;  8JDW A;  1G61 A;  4YTG A;  2JAJ A;  9JDW A;  7JDW A;  4N2N A;  1H70 A;  3I2E A;  2JDW A;  2Q3U A;  4YT9 A;  4N26 A;  3JDW A;  1ZBR A;  2CI7 A;  1S9R A;  4X8G A;  2DEY X;  1G62 A;  4N2A A;  1JDX A;  4X8C A;  4N25 A;  4N2B A;  4N2L A;  3APN A;  4YTB A;  4N2D A;  5JDW A;  2EWO A;  1VKP A;  4N2K A;  4DKT A;  6JDW A;  3P8P A;  2C6Z A;  1RXX A;  4N2C A;  4N2E A;  4BOF A;  4N28 A;  5AN9 I;  4E4J A;  4N2M A;  3H7K A;  5HP5 A;  2CI5 A;  5AK7 A;  3HVM A;  2JER A;  4N2F A;  3I4A A;  2CI3 A;  3B1T A;  4N22 A;  1WDA A;  3B1U A;  4N20 A;  1WD9 A;  3APM A;  5AK8 A;  2CMU A;  2CI4 A;  4N2H A;  1BWD A;  3P8E A;  4JDW A;  3H7C X;  3RHY A;  2AAF A;  2DEX X;  4N24 A;  2ABR A;  1XKN A;  2JDX A;  1JDW A;  4N2I A;  4N2G A;  5M3Q A;  2A9G A;  2DW5 A;  2JAI A;  2ACI A;  2CI6 A;  3BPB A;  2CI1 A; 
#chains in the Genus database with same CATH topology
 1LXY A;  1WD8 A;  2DEW X;  8JDW A;  1G61 A;  4YTG A;  2JAJ A;  9JDW A;  7JDW A;  4N2N A;  1H70 A;  3I2E A;  2JDW A;  2Q3U A;  4YT9 A;  4N26 A;  3JDW A;  1ZBR A;  2CI7 A;  1S9R A;  4X8G A;  2DEY X;  1G62 A;  4N2A A;  1JDX A;  4X8C A;  4N25 A;  4N2B A;  4N2L A;  3APN A;  4YTB A;  4N2D A;  5JDW A;  2EWO A;  1VKP A;  4N2K A;  1YNI A;  4DKT A;  6JDW A;  3P8P A;  2C6Z A;  1RXX A;  4N2C A;  4N2E A;  4BOF A;  4N28 A;  5AN9 I;  4E4J A;  4N2M A;  3H7K A;  5HP5 A;  2CI5 A;  5AK7 A;  3HVM A;  2JER A;  4N2F A;  3I4A A;  2CI3 A;  3B1T A;  4N22 A;  1WDA A;  3B1U A;  4N20 A;  1WD9 A;  3APM A;  5AK8 A;  2CMU A;  2CI4 A;  4N2H A;  1BWD A;  1YNH A;  3P8E A;  4JDW A;  3H7C X;  3RHY A;  2AAF A;  2DEX X;  4N24 A;  2ABR A;  1XKN A;  1YNF A;  2JDX A;  1JDW A;  4N2I A;  4N2G A;  5M3Q A;  2A9G A;  2DW5 A;  2JAI A;  2ACI A;  2CI6 A;  3BPB A;  2CI1 A; 
#chains in the Genus database with same CATH homology
 1LXY A;  1WD8 A;  2DEW X;  8JDW A;  1G61 A;  4YTG A;  2JAJ A;  9JDW A;  7JDW A;  4N2N A;  1H70 A;  3I2E A;  2JDW A;  2Q3U A;  4YT9 A;  4N26 A;  3JDW A;  1ZBR A;  2CI7 A;  1S9R A;  4X8G A;  2DEY X;  1G62 A;  4N2A A;  1JDX A;  4X8C A;  4N25 A;  4N2B A;  4N2L A;  3APN A;  4YTB A;  4N2D A;  5JDW A;  2EWO A;  1VKP A;  4N2K A;  4DKT A;  6JDW A;  3P8P A;  2C6Z A;  1RXX A;  4N2C A;  4N2E A;  4BOF A;  4N28 A;  5AN9 I;  4E4J A;  4N2M A;  3H7K A;  5HP5 A;  2CI5 A;  5AK7 A;  3HVM A;  2JER A;  4N2F A;  3I4A A;  2CI3 A;  3B1T A;  4N22 A;  1WDA A;  3B1U A;  4N20 A;  1WD9 A;  3APM A;  5AK8 A;  2CMU A;  2CI4 A;  4N2H A;  1BWD A;  3P8E A;  4JDW A;  3H7C X;  3RHY A;  2AAF A;  2DEX X;  4N24 A;  2ABR A;  1XKN A;  2JDX A;  1JDW A;  4N2I A;  4N2G A;  5M3Q A;  2A9G A;  2DW5 A;  2JAI A;  2ACI A;  2CI6 A;  3BPB A;  2CI1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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