2AWAA

Crystal structure of dna polymerase iii, beta chain (ec 2.7.7.7) (np_344555.1) from streptococcus pneumoniae tigr4 at 2.50 a resolution
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
377
structure length
377
Chain Sequence
MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of DNA polymerase III, beta chain (EC 2.7.7.7) (np_344555.1) from STREPTOCOCCUS PNEUMONIAE TIGR4 at 2.50 A resolution
rcsb
molecule tags Transferase
source organism Streptococcus pneumoniae
molecule keywords DNA polymerase III, beta chain
total genus 94
structure length 377
sequence length 377
chains with identical sequence B, C, D
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2005-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 2awaA01
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2awaA02
1YYPA 3I2MX 2ZVMA 3V61B 1RWZA 4N98A 3V62B 2HIKA 2AWAA 1VYMA 3G65C 1PLRA 1B77A 2NTIC 1RXMA 3AIXA 5IXAA 2Z0LA 4PNUA 4MJRA 4TSZA 3AIZC 2IO4B 3P91A 3LX1A 5B7OA 1U7BA 5JNED 4HK1A 3WGWA 3PWEA 4K3OA 4N97A 1GE8A 4PNVA 2HIIA 3A2FB 3IFVA 5IWDA 4ZTDA 3RB9A 1RXZA 3F1VA 2OD8A 2IJXA 3FDSC 3Q4KA 3L0WA 3TBLA 5FRQA 4N96A 3BEPA 1VYJA 4L60A 5AUJA 3QSBB 3U5ZF 4OVHA 2IZOC 3D1FA 1AXCA 1CZDA 1U76A 2IX2C 1DMLA 3D1EA 3G65B 3GPNA 4K3KA 4N95A 2NTIB 4K3PA 1PLQA 2HIKC 3F1WA 3HI8A 1SXJF 3GGRA 5A6DA 4PNWA 4N99A 3A1JA 5AH4A 1JQLA 5AGUA 2ZVLA 3AIXB 2POLA 3LX2A 4S3IA 4CS5A 4RKIA 5AGVA 2ZVWA 3P83A 4MJQA 3U60F 4TR6A 5E0VA 2HIIC 3HSLX 4TR7A 4MJPA 4N94A 3A1JC 4K3SA 4N9AA 2IZOB 4TR8A 1UNNA 4YHRA 3P87A 2IX2B 2AVTA 4K74A 5DAIA 3L0XA 1IZ4A 4RJFA 3G65A 1UD9A 5CFKA 3Q4JA 2ZVKA 2IO4A 1T6LA 1IZ5A 2HIKB 5HACA 1MMIA 5DA7A 5IY4A 3AIZA 5AH2A 4K3QA 3K4XA 4K3RA 4OVFA 5H0TA 3GGRC 1UL1A 1B8HA 3L10A 3GGRB 1W60A 2HIIB 1OK7A 3QSBA 4K3LA 3P16A 5FVEA 3T0PA 1JQJA 3D1GA 4OVGA 3A1JB 3FDSD 4L6PA 1VPKA 5E0TA 1ISQA 3PGEB 5E0UA 4D2GA 4K3MA 3GPMA 3U61F 2NTIA 2IX2A 4TRTA 2ZVVA 3VKXA 2XURA 3V60B 3Q4LA
chains in the Genus database with same CATH superfamily
1YYPA 3I2MX 2ZVMA 3V61B 1RWZA 4N98A 3V62B 2HIKA 2AWAA 1VYMA 3G65C 1PLRA 1B77A 2NTIC 1RXMA 3L0XB 3AIXA 5IXAA 2Z0LA 4PNUA 4MJRA 4TSZA 3AIZC 2IO4B 3P91A 3LX1A 5B7OA 1U7BA 5JNED 4HK1A 3WGWA 3PWEA 4K3OA 4N97A 1GE8A 4PNVA 2HIIA 3A2FB 3IFVA 5IWDA 4ZTDA 3RB9A 1RXZA 3F1VA 2OD8A 2IJXA 3FDSC 3Q4KA 3L0WA 3L10B 3TBLA 5FRQA 4N96A 3BEPA 1VYJA 4L60A 5AUJA 3QSBB 3U5ZF 4OVHA 2IZOC 3D1FA 1AXCA 1CZDA 1U76A 2IX2C 1DMLA 3D1EA 3G65B 3GPNA 4K3KA 4N95A 2NTIB 4K3PA 1PLQA 2HIKC 3F1WA 3HI8A 1SXJF 3GGRA 5A6DA 4PNWA 4N99A 3A1JA 5AH4A 1JQLA 5AGUA 2ZVLA 3AIXB 2POLA 3LX2A 4S3IA 4CS5A 4RKIA 5AGVA 3PGEA 2ZVWA 3P83A 4MJQA 3U60F 4TR6A 5E0VA 2HIIC 3HSLX 4TR7A 4MJPA 4N94A 3A1JC 4K3SA 4N9AA 2IZOB 4TR8A 1UNNA 4YHRA 3P87A 2IX2B 2AVTA 4K74A 5DAIA 3L0XA 1IZ4A 4RJFA 3G65A 1UD9A 3L0WB 5CFKA 3Q4JA 2ZVKA 2IO4A 1T6LA 1IZ5A 2HIKB 5HACA 1MMIA 5DA7A 5IY4A 3AIZA 5AH2A 4K3QA 3K4XA 4K3RA 4OVFA 5H0TA 3GGRC 1UL1A 1B8HA 3L10A 3GGRB 1W60A 2HIIB 1OK7A 3QSBA 4K3LA 3P16A 5FVEA 3T0PA 1JQJA 3D1GA 4OVGA 3A1JB 3FDSD 4L6PA 1VPKA 5E0TA 1ISQA 3PGEB 5E0UA 4D2GA 4K3MA 3GPMA 3U61F 2NTIA 2IX2A 4TRTA 2ZVVA 3VKXA 2XURA 3V60B 3Q4LA
chains in the Genus database with same CATH topology
1YYPA 3I2MX 2ZVMA 3V61B 1RWZA 4N98A 3V62B 2HIKA 2AWAA 1VYMA 3G65C 1PLRA 1B77A 2NTIC 1RXMA 3AIXA 5IXAA 2Z0LA 4PNUA 4MJRA 4TSZA 3AIZC 2IO4B 3P91A 3LX1A 5B7OA 1U7BA 5JNED 4HK1A 3WGWA 3PWEA 4K3OA 4N97A 1GE8A 4PNVA 2HIIA 3A2FB 3IFVA 5IWDA 4ZTDA 3RB9A 1RXZA 3F1VA 2OD8A 2IJXA 3FDSC 3Q4KA 3L0WA 3TBLA 5FRQA 4N96A 3BEPA 1VYJA 4L60A 5AUJA 3QSBB 3U5ZF 4OVHA 2IZOC 3D1FA 1AXCA 1CZDA 1U76A 2IX2C 1DMLA 3D1EA 3G65B 3GPNA 4K3KA 4N95A 2NTIB 4K3PA 1PLQA 2HIKC 3F1WA 3HI8A 1SXJF 3GGRA 5A6DA 4PNWA 4N99A 3A1JA 5AH4A 1JQLA 5AGUA 2ZVLA 3AIXB 2POLA 3LX2A 4S3IA 4CS5A 4RKIA 5AGVA 2ZVWA 3P83A 4MJQA 3U60F 4TR6A 5E0VA 2HIIC 3HSLX 4TR7A 4MJPA 4N94A 3A1JC 4K3SA 4N9AA 2IZOB 4TR8A 1UNNA 4YHRA 3P87A 2IX2B 2AVTA 4K74A 5DAIA 3L0XA 1IZ4A 4RJFA 3G65A 1UD9A 5CFKA 3Q4JA 2ZVKA 2IO4A 1T6LA 1IZ5A 2HIKB 5HACA 1MMIA 5DA7A 5IY4A 3AIZA 5AH2A 4K3QA 3K4XA 4K3RA 4OVFA 5H0TA 3GGRC 1UL1A 1B8HA 3L10A 3GGRB 1W60A 2HIIB 1OK7A 3QSBA 4K3LA 3P16A 5FVEA 3T0PA 1JQJA 3D1GA 4OVGA 3A1JB 3FDSD 4L6PA 1VPKA 5E0TA 1ISQA 3PGEB 5E0UA 4D2GA 4K3MA 3GPMA 3U61F 2NTIA 2IX2A 4TRTA 2ZVVA 3VKXA 2XURA 3V60B 3Q4LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YYP A;  3I2M X;  2ZVM A;  3V61 B;  1RWZ A;  4N98 A;  3V62 B;  2HIK A;  2AWA A;  1VYM A;  3G65 C;  1PLR A;  1B77 A;  2NTI C;  1RXM A;  3AIX A;  5IXA A;  2Z0L A;  4PNU A;  4MJR A;  4TSZ A;  3AIZ C;  2IO4 B;  3P91 A;  3LX1 A;  5B7O A;  1U7B A;  5JNE D;  4HK1 A;  3WGW A;  3PWE A;  4K3O A;  4N97 A;  1GE8 A;  4PNV A;  2HII A;  3A2F B;  3IFV A;  5IWD A;  4ZTD A;  3RB9 A;  1RXZ A;  3F1V A;  2OD8 A;  2IJX A;  3FDS C;  3Q4K A;  3L0W A;  3TBL A;  5FRQ A;  4N96 A;  3BEP A;  1VYJ A;  4L60 A;  5AUJ A;  3QSB B;  3U5Z F;  4OVH A;  2IZO C;  3D1F A;  1AXC A;  1CZD A;  1U76 A;  2IX2 C;  1DML A;  3D1E A;  3G65 B;  3GPN A;  4K3K A;  4N95 A;  2NTI B;  4K3P A;  1PLQ A;  2HIK C;  3F1W A;  3HI8 A;  1SXJ F;  3GGR A;  5A6D A;  4PNW A;  4N99 A;  3A1J A;  5AH4 A;  1JQL A;  5AGU A;  2ZVL A;  3AIX B;  2POL A;  3LX2 A;  4S3I A;  4CS5 A;  4RKI A;  5AGV A;  2ZVW A;  3P83 A;  4MJQ A;  3U60 F;  4TR6 A;  5E0V A;  2HII C;  3HSL X;  4TR7 A;  4MJP A;  4N94 A;  3A1J C;  4K3S A;  4N9A A;  2IZO B;  4TR8 A;  1UNN A;  4YHR A;  3P87 A;  2IX2 B;  2AVT A;  4K74 A;  5DAI A;  3L0X A;  1IZ4 A;  4RJF A;  3G65 A;  1UD9 A;  5CFK A;  3Q4J A;  2ZVK A;  2IO4 A;  1T6L A;  1IZ5 A;  2HIK B;  5HAC A;  1MMI A;  5DA7 A;  5IY4 A;  3AIZ A;  5AH2 A;  4K3Q A;  3K4X A;  4K3R A;  4OVF A;  5H0T A;  3GGR C;  1UL1 A;  1B8H A;  3L10 A;  3GGR B;  1W60 A;  2HII B;  1OK7 A;  3QSB A;  4K3L A;  3P16 A;  5FVE A;  3T0P A;  1JQJ A;  3D1G A;  4OVG A;  3A1J B;  3FDS D;  4L6P A;  1VPK A;  5E0T A;  1ISQ A;  3PGE B;  5E0U A;  4D2G A;  4K3M A;  3GPM A;  3U61 F;  2NTI A;  2IX2 A;  4TRT A;  2ZVV A;  3VKX A;  2XUR A;  3V60 B;  3Q4L A; 
#chains in the Genus database with same CATH topology
 1YYP A;  3I2M X;  2ZVM A;  3V61 B;  1RWZ A;  4N98 A;  3V62 B;  2HIK A;  2AWA A;  1VYM A;  3G65 C;  1PLR A;  1B77 A;  2NTI C;  1RXM A;  3L0X B;  3AIX A;  5IXA A;  2Z0L A;  4PNU A;  4MJR A;  4TSZ A;  3AIZ C;  2IO4 B;  3P91 A;  3LX1 A;  5B7O A;  1U7B A;  5JNE D;  4HK1 A;  3WGW A;  3PWE A;  4K3O A;  4N97 A;  1GE8 A;  4PNV A;  2HII A;  3A2F B;  3IFV A;  5IWD A;  4ZTD A;  3RB9 A;  1RXZ A;  3F1V A;  2OD8 A;  2IJX A;  3FDS C;  3Q4K A;  3L0W A;  3L10 B;  3TBL A;  5FRQ A;  4N96 A;  3BEP A;  1VYJ A;  4L60 A;  5AUJ A;  3QSB B;  3U5Z F;  4OVH A;  2IZO C;  3D1F A;  1AXC A;  1CZD A;  1U76 A;  2IX2 C;  1DML A;  3D1E A;  3G65 B;  3GPN A;  4K3K A;  4N95 A;  2NTI B;  4K3P A;  1PLQ A;  2HIK C;  3F1W A;  3HI8 A;  1SXJ F;  3GGR A;  5A6D A;  4PNW A;  4N99 A;  3A1J A;  5AH4 A;  1JQL A;  5AGU A;  2ZVL A;  3AIX B;  2POL A;  3LX2 A;  4S3I A;  4CS5 A;  4RKI A;  5AGV A;  3PGE A;  2ZVW A;  3P83 A;  4MJQ A;  3U60 F;  4TR6 A;  5E0V A;  2HII C;  3HSL X;  4TR7 A;  4MJP A;  4N94 A;  3A1J C;  4K3S A;  4N9A A;  2IZO B;  4TR8 A;  1UNN A;  4YHR A;  3P87 A;  2IX2 B;  2AVT A;  4K74 A;  5DAI A;  3L0X A;  1IZ4 A;  4RJF A;  3G65 A;  1UD9 A;  3L0W B;  5CFK A;  3Q4J A;  2ZVK A;  2IO4 A;  1T6L A;  1IZ5 A;  2HIK B;  5HAC A;  1MMI A;  5DA7 A;  5IY4 A;  3AIZ A;  5AH2 A;  4K3Q A;  3K4X A;  4K3R A;  4OVF A;  5H0T A;  3GGR C;  1UL1 A;  1B8H A;  3L10 A;  3GGR B;  1W60 A;  2HII B;  1OK7 A;  3QSB A;  4K3L A;  3P16 A;  5FVE A;  3T0P A;  1JQJ A;  3D1G A;  4OVG A;  3A1J B;  3FDS D;  4L6P A;  1VPK A;  5E0T A;  1ISQ A;  3PGE B;  5E0U A;  4D2G A;  4K3M A;  3GPM A;  3U61 F;  2NTI A;  2IX2 A;  4TRT A;  2ZVV A;  3VKX A;  2XUR A;  3V60 B;  3Q4L A; 
#chains in the Genus database with same CATH homology
 1YYP A;  3I2M X;  2ZVM A;  3V61 B;  1RWZ A;  4N98 A;  3V62 B;  2HIK A;  2AWA A;  1VYM A;  3G65 C;  1PLR A;  1B77 A;  2NTI C;  1RXM A;  3AIX A;  5IXA A;  2Z0L A;  4PNU A;  4MJR A;  4TSZ A;  3AIZ C;  2IO4 B;  3P91 A;  3LX1 A;  5B7O A;  1U7B A;  5JNE D;  4HK1 A;  3WGW A;  3PWE A;  4K3O A;  4N97 A;  1GE8 A;  4PNV A;  2HII A;  3A2F B;  3IFV A;  5IWD A;  4ZTD A;  3RB9 A;  1RXZ A;  3F1V A;  2OD8 A;  2IJX A;  3FDS C;  3Q4K A;  3L0W A;  3TBL A;  5FRQ A;  4N96 A;  3BEP A;  1VYJ A;  4L60 A;  5AUJ A;  3QSB B;  3U5Z F;  4OVH A;  2IZO C;  3D1F A;  1AXC A;  1CZD A;  1U76 A;  2IX2 C;  1DML A;  3D1E A;  3G65 B;  3GPN A;  4K3K A;  4N95 A;  2NTI B;  4K3P A;  1PLQ A;  2HIK C;  3F1W A;  3HI8 A;  1SXJ F;  3GGR A;  5A6D A;  4PNW A;  4N99 A;  3A1J A;  5AH4 A;  1JQL A;  5AGU A;  2ZVL A;  3AIX B;  2POL A;  3LX2 A;  4S3I A;  4CS5 A;  4RKI A;  5AGV A;  2ZVW A;  3P83 A;  4MJQ A;  3U60 F;  4TR6 A;  5E0V A;  2HII C;  3HSL X;  4TR7 A;  4MJP A;  4N94 A;  3A1J C;  4K3S A;  4N9A A;  2IZO B;  4TR8 A;  1UNN A;  4YHR A;  3P87 A;  2IX2 B;  2AVT A;  4K74 A;  5DAI A;  3L0X A;  1IZ4 A;  4RJF A;  3G65 A;  1UD9 A;  5CFK A;  3Q4J A;  2ZVK A;  2IO4 A;  1T6L A;  1IZ5 A;  2HIK B;  5HAC A;  1MMI A;  5DA7 A;  5IY4 A;  3AIZ A;  5AH2 A;  4K3Q A;  3K4X A;  4K3R A;  4OVF A;  5H0T A;  3GGR C;  1UL1 A;  1B8H A;  3L10 A;  3GGR B;  1W60 A;  2HII B;  1OK7 A;  3QSB A;  4K3L A;  3P16 A;  5FVE A;  3T0P A;  1JQJ A;  3D1G A;  4OVG A;  3A1J B;  3FDS D;  4L6P A;  1VPK A;  5E0T A;  1ISQ A;  3PGE B;  5E0U A;  4D2G A;  4K3M A;  3GPM A;  3U61 F;  2NTI A;  2IX2 A;  4TRT A;  2ZVV A;  3VKX A;  2XUR A;  3V60 B;  3Q4L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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