2CI5A

Crystal structure of dimethylarginine dimethylaminohydrolase i in complex with l-homocysteine
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
272
structure length
272
Chain Sequence
FGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inbitors
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1
total genus 89
structure length 272
sequence length 272
chains with identical sequence B
ec nomenclature ec 3.5.3.18: Dimethylargininase.
pdb deposition date 2006-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2ci5A00
1S9RA 1ZBRA 4N26A 2JDWA 6JDWA 1WDAA 2CMUA 2DEXX 4YTBA 2JAJA 4N2GA 2DEWX 5AK7A 2JDXA 4N2CA 1JDWA 4BOFA 3B1UA 4N28A 4N20A 4YTGA 4N2DA 1G62A 5JDWA 2CI7A 1JDXA 2CI1A 4N2FA 1LXYA 3P8PA 5AN9I 3JDWA 2EWOA 2ACIA 3H7CX 2DEYX 2JAIA 4JDWA 3APNA 2C6ZA 4X8GA 4N22A 4N25A 1BWDA 2CI4A 2Q3UA 4N2KA 1XKNA 2CI6A 4N2AA 3I2EA 4N2LA 1VKPA 4N2EA 1WD8A 3B1TA 4N2HA 4E4JA 2CI3A 5AK8A 8JDWA 4N24A 1WD9A 3RHYA 3APMA 4N2MA 4DKTA 4N2IA 4X8CA 5M3QA 2A9GA 3H7KA 2ABRA 1G61A 3HVMA 1H70A 2CI5A 3P8EA 7JDWA 2DW5A 5HP5A 3BPBA 2AAFA 9JDWA 1RXXA 2JERA 4N2BA 4N2NA 3I4AA 4YT9A
chains in the Genus database with same CATH superfamily
1S9RA 1ZBRA 4N26A 2JDWA 6JDWA 1WDAA 2CMUA 2DEXX 4YTBA 2JAJA 4N2GA 2DEWX 5AK7A 2JDXA 4N2CA 1JDWA 4BOFA 3B1UA 4N28A 4N20A 4YTGA 4N2DA 1G62A 5JDWA 2CI7A 1JDXA 2CI1A 4N2FA 1LXYA 3P8PA 5AN9I 3JDWA 2EWOA 2ACIA 3H7CX 2DEYX 2JAIA 4JDWA 3APNA 2C6ZA 4X8GA 4N22A 4N25A 1YNIA 1BWDA 2CI4A 2Q3UA 4N2KA 1XKNA 2CI6A 4N2AA 3I2EA 4N2LA 1VKPA 4N2EA 1WD8A 3B1TA 4N2HA 4E4JA 2CI3A 1YNFA 5AK8A 8JDWA 4N24A 1WD9A 3RHYA 3APMA 4N2MA 4DKTA 4N2IA 4X8CA 5M3QA 2A9GA 3H7KA 2ABRA 1G61A 3HVMA 1H70A 2CI5A 3P8EA 7JDWA 1YNHA 2DW5A 5HP5A 3BPBA 2AAFA 9JDWA 1RXXA 2JERA 4N2BA 4N2NA 3I4AA 4YT9A
chains in the Genus database with same CATH topology
1S9RA 1ZBRA 4N26A 2JDWA 6JDWA 1WDAA 2CMUA 2DEXX 4YTBA 2JAJA 4N2GA 2DEWX 5AK7A 2JDXA 4N2CA 1JDWA 4BOFA 3B1UA 4N28A 4N20A 4YTGA 4N2DA 1G62A 5JDWA 2CI7A 1JDXA 2CI1A 4N2FA 1LXYA 3P8PA 5AN9I 3JDWA 2EWOA 2ACIA 3H7CX 2DEYX 2JAIA 4JDWA 3APNA 2C6ZA 4X8GA 4N22A 4N25A 1BWDA 2CI4A 2Q3UA 4N2KA 1XKNA 2CI6A 4N2AA 3I2EA 4N2LA 1VKPA 4N2EA 1WD8A 3B1TA 4N2HA 4E4JA 2CI3A 5AK8A 8JDWA 4N24A 1WD9A 3RHYA 3APMA 4N2MA 4DKTA 4N2IA 4X8CA 5M3QA 2A9GA 3H7KA 2ABRA 1G61A 3HVMA 1H70A 2CI5A 3P8EA 7JDWA 2DW5A 5HP5A 3BPBA 2AAFA 9JDWA 1RXXA 2JERA 4N2BA 4N2NA 3I4AA 4YT9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S9R A;  1ZBR A;  4N26 A;  2JDW A;  6JDW A;  1WDA A;  2CMU A;  2DEX X;  4YTB A;  2JAJ A;  4N2G A;  2DEW X;  5AK7 A;  2JDX A;  4N2C A;  1JDW A;  4BOF A;  3B1U A;  4N28 A;  4N20 A;  4YTG A;  4N2D A;  1G62 A;  5JDW A;  2CI7 A;  1JDX A;  2CI1 A;  4N2F A;  1LXY A;  3P8P A;  5AN9 I;  3JDW A;  2EWO A;  2ACI A;  3H7C X;  2DEY X;  2JAI A;  4JDW A;  3APN A;  2C6Z A;  4X8G A;  4N22 A;  4N25 A;  1BWD A;  2CI4 A;  2Q3U A;  4N2K A;  1XKN A;  2CI6 A;  4N2A A;  3I2E A;  4N2L A;  1VKP A;  4N2E A;  1WD8 A;  3B1T A;  4N2H A;  4E4J A;  2CI3 A;  5AK8 A;  8JDW A;  4N24 A;  1WD9 A;  3RHY A;  3APM A;  4N2M A;  4DKT A;  4N2I A;  4X8C A;  5M3Q A;  2A9G A;  3H7K A;  2ABR A;  1G61 A;  3HVM A;  1H70 A;  2CI5 A;  3P8E A;  7JDW A;  2DW5 A;  5HP5 A;  3BPB A;  2AAF A;  9JDW A;  1RXX A;  2JER A;  4N2B A;  4N2N A;  3I4A A;  4YT9 A; 
#chains in the Genus database with same CATH topology
 1S9R A;  1ZBR A;  4N26 A;  2JDW A;  6JDW A;  1WDA A;  2CMU A;  2DEX X;  4YTB A;  2JAJ A;  4N2G A;  2DEW X;  5AK7 A;  2JDX A;  4N2C A;  1JDW A;  4BOF A;  3B1U A;  4N28 A;  4N20 A;  4YTG A;  4N2D A;  1G62 A;  5JDW A;  2CI7 A;  1JDX A;  2CI1 A;  4N2F A;  1LXY A;  3P8P A;  5AN9 I;  3JDW A;  2EWO A;  2ACI A;  3H7C X;  2DEY X;  2JAI A;  4JDW A;  3APN A;  2C6Z A;  4X8G A;  4N22 A;  4N25 A;  1YNI A;  1BWD A;  2CI4 A;  2Q3U A;  4N2K A;  1XKN A;  2CI6 A;  4N2A A;  3I2E A;  4N2L A;  1VKP A;  4N2E A;  1WD8 A;  3B1T A;  4N2H A;  4E4J A;  2CI3 A;  1YNF A;  5AK8 A;  8JDW A;  4N24 A;  1WD9 A;  3RHY A;  3APM A;  4N2M A;  4DKT A;  4N2I A;  4X8C A;  5M3Q A;  2A9G A;  3H7K A;  2ABR A;  1G61 A;  3HVM A;  1H70 A;  2CI5 A;  3P8E A;  7JDW A;  1YNH A;  2DW5 A;  5HP5 A;  3BPB A;  2AAF A;  9JDW A;  1RXX A;  2JER A;  4N2B A;  4N2N A;  3I4A A;  4YT9 A; 
#chains in the Genus database with same CATH homology
 1S9R A;  1ZBR A;  4N26 A;  2JDW A;  6JDW A;  1WDA A;  2CMU A;  2DEX X;  4YTB A;  2JAJ A;  4N2G A;  2DEW X;  5AK7 A;  2JDX A;  4N2C A;  1JDW A;  4BOF A;  3B1U A;  4N28 A;  4N20 A;  4YTG A;  4N2D A;  1G62 A;  5JDW A;  2CI7 A;  1JDX A;  2CI1 A;  4N2F A;  1LXY A;  3P8P A;  5AN9 I;  3JDW A;  2EWO A;  2ACI A;  3H7C X;  2DEY X;  2JAI A;  4JDW A;  3APN A;  2C6Z A;  4X8G A;  4N22 A;  4N25 A;  1BWD A;  2CI4 A;  2Q3U A;  4N2K A;  1XKN A;  2CI6 A;  4N2A A;  3I2E A;  4N2L A;  1VKP A;  4N2E A;  1WD8 A;  3B1T A;  4N2H A;  4E4J A;  2CI3 A;  5AK8 A;  8JDW A;  4N24 A;  1WD9 A;  3RHY A;  3APM A;  4N2M A;  4DKT A;  4N2I A;  4X8C A;  5M3Q A;  2A9G A;  3H7K A;  2ABR A;  1G61 A;  3HVM A;  1H70 A;  2CI5 A;  3P8E A;  7JDW A;  2DW5 A;  5HP5 A;  3BPB A;  2AAF A;  9JDW A;  1RXX A;  2JER A;  4N2B A;  4N2N A;  3I4A A;  4YT9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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