2CS2A

Solution structure of the second zn-finger domain of poly(adp-ribose) polymerase-1
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
134
structure length
134
Chain Sequence
GSSGSSGGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the second Zn-finger domain of poly(ADP-ribose) polymerase-1
rcsb
molecule keywords Poly [ADP-ribose] polymerase-1
molecule tags Transferase
source organism Homo sapiens
total genus 15
structure length 134
sequence length 134
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2005-05-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00645 zf-PARP Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1740.10 Alpha Beta 2-Layer Sandwich first zn-finger domain of poly(adp-ribose) polymerase-1 Zinc finger, PARP-type 2cs2A01
2L31A 4DQYA 3ODAA 4AV1A 3OD8A 1UW0A 2L30A 4OQBA 2DMJA 2CS2A 3ODEA 4OPXA 4OQAA 3ODCA 2N8AA 1V9XA
chains in the Genus database with same CATH superfamily
3ODAA 3J80a 2DMJA 3ODEA 3ODCA 5FLXa 2L31A 3J81a 4DQYA 1UW0A 2L30A 5LL6e 5IT9a 4OQAA 2N8AA 4OPXA 3J7A3 4AV1A 4OQBA 5A2Qa 1V9XA 3JAMa 3OD8A 2CS2A
chains in the Genus database with same CATH topology
2L31A 4DQYA 3ODAA 4AV1A 3OD8A 1UW0A 2L30A 4OQBA 2DMJA 2CS2A 3ODEA 4OPXA 4OQAA 3ODCA 2N8AA 1V9XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L31 A;  4DQY A;  3ODA A;  4AV1 A;  3OD8 A;  1UW0 A;  2L30 A;  4OQB A;  2DMJ A;  2CS2 A;  3ODE A;  4OPX A;  4OQA A;  3ODC A;  2N8A A;  1V9X A; 
#chains in the Genus database with same CATH topology
 3ODA A;  3J80 a;  2DMJ A;  3ODE A;  3ODC A;  5FLX a;  2L31 A;  3J81 a;  4DQY A;  1UW0 A;  2L30 A;  5LL6 e;  5IT9 a;  4OQA A;  2N8A A;  4OPX A;  3J7A 3;  4AV1 A;  4OQB A;  5A2Q a;  1V9X A;  3JAM a;  3OD8 A;  2CS2 A; 
#chains in the Genus database with same CATH homology
 2L31 A;  4DQY A;  3ODA A;  4AV1 A;  3OD8 A;  1UW0 A;  2L30 A;  4OQB A;  2DMJ A;  2CS2 A;  3ODE A;  4OPX A;  4OQA A;  3ODC A;  2N8A A;  1V9X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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