2DDIA

Nmr structure of the second kunitz domain of human wfikkn1
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
70
structure length
70
Chain Sequence
EAEAEFTDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVVDHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords WAP, follistatin/kazal, immunoglobulin, kunitz and netrin do
total genus 15
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 2006-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 2ddiA00
2R9PE 3TPII 1G6XA 1FAKI 1LD6A 1KNTA 1YKTB 1T8NB 1FANA 5JB4A 1PITA 1KTHA 1TCPA 7PTIA 3TGJI 3OFWA 1OA55 1AALA 4BD9B 5C67C 1OA65 3T62D 1Y62A 2TPII 3BTTI 1EJMB 3LDMA 2LFKA 1YLCB 2HEXA 4BQDA 2TGPI 2W8XA 2ODYE 4DG4C 1TAWB 1UUBA 2KAII 1JV8A 2FTMB 4U30W 1EAWB 1DENA 1JC6A 4WXVC 1TPAI 4ISLB 8PTIA 2FI4I 3AUDA 3FP7J 2FTLI 2PTCI 1T7CB 4U32X 1P2MB 2UUYB 3P92E 1DTKA 2CA7A 3BTQI 3AUEA 1DTXA 3AUGA 2DDJA 1D0DA 3BTFI 3L3TE 5JB7A 3BTMI 3P95E 1B0CA 1TAPA 2FI5I 2RA3C 3D65I 3UIRC 1BRCI 1BF0A 1KUNA 1MTND 1P2KI 1BZ5A 1BRBI 1D0DB 4NTWB 1YLDB 2M99A 1BZXI 3TGKI 1KIGI 3M7QB 2UUXA 1P2NB 2M01A 1UUAA 1NAGA 3BTKI 1BIKA 3UOUB 2LFLA 3OTJI 2DDIA 1AAPA 1BHCA 4ISNB 2ZVXA 3LDIA 1P2QB 1SHPA 1BUNB 1P2II 2FI3I 1T8MB 3CI7A 4Y0YI 3TGII 1IRHA 1BTHP 3BYBA 1P2JI 2ZJXA 1K6UA 2JOTA 3U1JE 1BTIA 4DTGK 1P2OB 3BTEI 3LDJA 3BTHI 1ADZA 1TOCR 3AUHA 3AUBA 3AUCA 4Y10I 2J6DA 2IJOI 1CA0D 1LD5A 1CO7I 1DEMA 3AUIA 3FP8I 3L33E 1BPTA 4BNRI 1JV9A 3BTWI 4NTYB 3WNYA 3BTGI 4ISOB 4Y11I 5JB6A 4TPII 2KNTA 5JB5A 1F5RI 1FY8I 1ZJDB 5PTIA 1F7ZI 1ZR0B 4WWYC 4PTIA 6PTIA 4NTXB 2KCRA 1QLQA 9PTIA 1BPIA 4Y0ZI 1YC0I 1TFXC 3BTDI 1CBWD 1T8LB 3FP6I 3GYMI 1T8OB
chains in the Genus database with same CATH superfamily
2R9PE 3TPII 1G6XA 1FAKI 1LD6A 1KNTA 1YKTB 1T8NB 1FANA 5JB4A 1PITA 1KTHA 1TCPA 7PTIA 3TGJI 3OFWA 1OA55 1AALA 4BD9B 5C67C 1OA65 3T62D 1Y62A 2TPII 3BTTI 1EJMB 3LDMA 2LFKA 1YLCB 2HEXA 4BQDA 2TGPI 2W8XA 2ODYE 4DG4C 1TAWB 1UUBA 2KAII 1JV8A 2FTMB 4U30W 1EAWB 1DENA 1JC6A 4WXVC 1TPAI 4ISLB 8PTIA 2FI4I 3AUDA 3FP7J 2FTLI 2PTCI 1T7CB 4U32X 1P2MB 2UUYB 3P92E 1DTKA 2CA7A 3BTQI 3AUEA 1DTXA 3AUGA 2DDJA 1D0DA 3BTFI 3L3TE 5JB7A 3BTMI 3P95E 1B0CA 1TAPA 2FI5I 2RA3C 3D65I 3UIRC 1BRCI 1BF0A 1KUNA 1MTND 1P2KI 1BZ5A 1BRBI 1D0DB 4NTWB 1YLDB 2M99A 1BZXI 3TGKI 1KIGI 3M7QB 2UUXA 1P2NB 2M01A 1UUAA 1NAGA 3BTKI 1BIKA 3UOUB 2LFLA 3OTJI 2DDIA 1AAPA 1BHCA 4ISNB 2ZVXA 3LDIA 1P2QB 1SHPA 1BUNB 1P2II 2FI3I 1T8MB 3CI7A 4Y0YI 3TGII 1IRHA 1BTHP 3BYBA 1P2JI 2ZJXA 1K6UA 2JOTA 3U1JE 1BTIA 4DTGK 1P2OB 3BTEI 3LDJA 3BTHI 1ADZA 1TOCR 3AUHA 3AUBA 3AUCA 4Y10I 2J6DA 2IJOI 1CA0D 1LD5A 1CO7I 1DEMA 3AUIA 3FP8I 3L33E 1BPTA 4BNRI 1JV9A 3BTWI 4NTYB 3WNYA 3BTGI 4ISOB 4Y11I 5JB6A 4TPII 2KNTA 5JB5A 1F5RI 1FY8I 1ZJDB 5PTIA 1F7ZI 1ZR0B 4WWYC 4PTIA 6PTIA 4NTXB 2KCRA 1QLQA 9PTIA 1BPIA 4Y0ZI 1YC0I 1TFXC 3BTDI 1CBWD 1T8LB 3FP6I 3GYMI 1T8OB
chains in the Genus database with same CATH topology
2R9PE 3TPII 1G6XA 1FAKI 1LD6A 1KNTA 1YKTB 1T8NB 1FANA 5JB4A 1PITA 1KTHA 1TCPA 7PTIA 3TGJI 3OFWA 1OA55 1AALA 4BD9B 5C67C 1OA65 3T62D 1Y62A 2TPII 3BTTI 1EJMB 3LDMA 2LFKA 1YLCB 2HEXA 4BQDA 2TGPI 2W8XA 2ODYE 4DG4C 1TAWB 1UUBA 2KAII 1JV8A 2FTMB 4U30W 1EAWB 1DENA 1JC6A 4WXVC 1TPAI 4ISLB 8PTIA 2FI4I 3AUDA 3FP7J 2FTLI 2PTCI 1T7CB 4U32X 1P2MB 2UUYB 3P92E 1DTKA 2CA7A 3BTQI 3AUEA 1DTXA 3AUGA 2DDJA 1D0DA 3BTFI 3L3TE 5JB7A 3BTMI 3P95E 1B0CA 1TAPA 2FI5I 2RA3C 3D65I 3UIRC 1BRCI 1BF0A 1KUNA 1MTND 1P2KI 1BZ5A 1BRBI 1D0DB 4NTWB 1YLDB 2M99A 1BZXI 3TGKI 1KIGI 3M7QB 2UUXA 1P2NB 2M01A 1UUAA 1NAGA 3BTKI 1BIKA 3UOUB 2LFLA 3OTJI 2DDIA 1AAPA 1BHCA 4ISNB 2ZVXA 3LDIA 1P2QB 1SHPA 1BUNB 1P2II 2FI3I 1T8MB 3CI7A 4Y0YI 3TGII 1IRHA 1BTHP 3BYBA 1P2JI 2ZJXA 1K6UA 2JOTA 3U1JE 1BTIA 4DTGK 1P2OB 3BTEI 3LDJA 3BTHI 1ADZA 1TOCR 3AUHA 3AUBA 3AUCA 4Y10I 2J6DA 2IJOI 1CA0D 1LD5A 1CO7I 1DEMA 3AUIA 3FP8I 3L33E 1BPTA 4BNRI 1JV9A 3BTWI 4NTYB 3WNYA 3BTGI 4ISOB 4Y11I 5JB6A 4TPII 2KNTA 5JB5A 1F5RI 1FY8I 1ZJDB 5PTIA 1F7ZI 1ZR0B 4WWYC 4PTIA 6PTIA 4NTXB 2KCRA 1QLQA 9PTIA 1BPIA 4Y0ZI 1YC0I 1TFXC 3BTDI 1CBWD 1T8LB 3FP6I 3GYMI 1T8OB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R9P E;  3TPI I;  1G6X A;  1FAK I;  1LD6 A;  1KNT A;  1YKT B;  1T8N B;  1FAN A;  5JB4 A;  1PIT A;  1KTH A;  1TCP A;  7PTI A;  3TGJ I;  3OFW A;  1OA5 5;  1AAL A;  4BD9 B;  5C67 C;  1OA6 5;  3T62 D;  1Y62 A;  2TPI I;  3BTT I;  1EJM B;  3LDM A;  2LFK A;  1YLC B;  2HEX A;  4BQD A;  2TGP I;  2W8X A;  2ODY E;  4DG4 C;  1TAW B;  1UUB A;  2KAI I;  1JV8 A;  2FTM B;  4U30 W;  1EAW B;  1DEN A;  1JC6 A;  4WXV C;  1TPA I;  4ISL B;  8PTI A;  2FI4 I;  3AUD A;  3FP7 J;  2FTL I;  2PTC I;  1T7C B;  4U32 X;  1P2M B;  2UUY B;  3P92 E;  1DTK A;  2CA7 A;  3BTQ I;  3AUE A;  1DTX A;  3AUG A;  2DDJ A;  1D0D A;  3BTF I;  3L3T E;  5JB7 A;  3BTM I;  3P95 E;  1B0C A;  1TAP A;  2FI5 I;  2RA3 C;  3D65 I;  3UIR C;  1BRC I;  1BF0 A;  1KUN A;  1MTN D;  1P2K I;  1BZ5 A;  1BRB I;  1D0D B;  4NTW B;  1YLD B;  2M99 A;  1BZX I;  3TGK I;  1KIG I;  3M7Q B;  2UUX A;  1P2N B;  2M01 A;  1UUA A;  1NAG A;  3BTK I;  1BIK A;  3UOU B;  2LFL A;  3OTJ I;  2DDI A;  1AAP A;  1BHC A;  4ISN B;  2ZVX A;  3LDI A;  1P2Q B;  1SHP A;  1BUN B;  1P2I I;  2FI3 I;  1T8M B;  3CI7 A;  4Y0Y I;  3TGI I;  1IRH A;  1BTH P;  3BYB A;  1P2J I;  2ZJX A;  1K6U A;  2JOT A;  3U1J E;  1BTI A;  4DTG K;  1P2O B;  3BTE I;  3LDJ A;  3BTH I;  1ADZ A;  1TOC R;  3AUH A;  3AUB A;  3AUC A;  4Y10 I;  2J6D A;  2IJO I;  1CA0 D;  1LD5 A;  1CO7 I;  1DEM A;  3AUI A;  3FP8 I;  3L33 E;  1BPT A;  4BNR I;  1JV9 A;  3BTW I;  4NTY B;  3WNY A;  3BTG I;  4ISO B;  4Y11 I;  5JB6 A;  4TPI I;  2KNT A;  5JB5 A;  1F5R I;  1FY8 I;  1ZJD B;  5PTI A;  1F7Z I;  1ZR0 B;  4WWY C;  4PTI A;  6PTI A;  4NTX B;  2KCR A;  1QLQ A;  9PTI A;  1BPI A;  4Y0Z I;  1YC0 I;  1TFX C;  3BTD I;  1CBW D;  1T8L B;  3FP6 I;  3GYM I;  1T8O B; 
#chains in the Genus database with same CATH topology
 2R9P E;  3TPI I;  1G6X A;  1FAK I;  1LD6 A;  1KNT A;  1YKT B;  1T8N B;  1FAN A;  5JB4 A;  1PIT A;  1KTH A;  1TCP A;  7PTI A;  3TGJ I;  3OFW A;  1OA5 5;  1AAL A;  4BD9 B;  5C67 C;  1OA6 5;  3T62 D;  1Y62 A;  2TPI I;  3BTT I;  1EJM B;  3LDM A;  2LFK A;  1YLC B;  2HEX A;  4BQD A;  2TGP I;  2W8X A;  2ODY E;  4DG4 C;  1TAW B;  1UUB A;  2KAI I;  1JV8 A;  2FTM B;  4U30 W;  1EAW B;  1DEN A;  1JC6 A;  4WXV C;  1TPA I;  4ISL B;  8PTI A;  2FI4 I;  3AUD A;  3FP7 J;  2FTL I;  2PTC I;  1T7C B;  4U32 X;  1P2M B;  2UUY B;  3P92 E;  1DTK A;  2CA7 A;  3BTQ I;  3AUE A;  1DTX A;  3AUG A;  2DDJ A;  1D0D A;  3BTF I;  3L3T E;  5JB7 A;  3BTM I;  3P95 E;  1B0C A;  1TAP A;  2FI5 I;  2RA3 C;  3D65 I;  3UIR C;  1BRC I;  1BF0 A;  1KUN A;  1MTN D;  1P2K I;  1BZ5 A;  1BRB I;  1D0D B;  4NTW B;  1YLD B;  2M99 A;  1BZX I;  3TGK I;  1KIG I;  3M7Q B;  2UUX A;  1P2N B;  2M01 A;  1UUA A;  1NAG A;  3BTK I;  1BIK A;  3UOU B;  2LFL A;  3OTJ I;  2DDI A;  1AAP A;  1BHC A;  4ISN B;  2ZVX A;  3LDI A;  1P2Q B;  1SHP A;  1BUN B;  1P2I I;  2FI3 I;  1T8M B;  3CI7 A;  4Y0Y I;  3TGI I;  1IRH A;  1BTH P;  3BYB A;  1P2J I;  2ZJX A;  1K6U A;  2JOT A;  3U1J E;  1BTI A;  4DTG K;  1P2O B;  3BTE I;  3LDJ A;  3BTH I;  1ADZ A;  1TOC R;  3AUH A;  3AUB A;  3AUC A;  4Y10 I;  2J6D A;  2IJO I;  1CA0 D;  1LD5 A;  1CO7 I;  1DEM A;  3AUI A;  3FP8 I;  3L33 E;  1BPT A;  4BNR I;  1JV9 A;  3BTW I;  4NTY B;  3WNY A;  3BTG I;  4ISO B;  4Y11 I;  5JB6 A;  4TPI I;  2KNT A;  5JB5 A;  1F5R I;  1FY8 I;  1ZJD B;  5PTI A;  1F7Z I;  1ZR0 B;  4WWY C;  4PTI A;  6PTI A;  4NTX B;  2KCR A;  1QLQ A;  9PTI A;  1BPI A;  4Y0Z I;  1YC0 I;  1TFX C;  3BTD I;  1CBW D;  1T8L B;  3FP6 I;  3GYM I;  1T8O B; 
#chains in the Genus database with same CATH homology
 2R9P E;  3TPI I;  1G6X A;  1FAK I;  1LD6 A;  1KNT A;  1YKT B;  1T8N B;  1FAN A;  5JB4 A;  1PIT A;  1KTH A;  1TCP A;  7PTI A;  3TGJ I;  3OFW A;  1OA5 5;  1AAL A;  4BD9 B;  5C67 C;  1OA6 5;  3T62 D;  1Y62 A;  2TPI I;  3BTT I;  1EJM B;  3LDM A;  2LFK A;  1YLC B;  2HEX A;  4BQD A;  2TGP I;  2W8X A;  2ODY E;  4DG4 C;  1TAW B;  1UUB A;  2KAI I;  1JV8 A;  2FTM B;  4U30 W;  1EAW B;  1DEN A;  1JC6 A;  4WXV C;  1TPA I;  4ISL B;  8PTI A;  2FI4 I;  3AUD A;  3FP7 J;  2FTL I;  2PTC I;  1T7C B;  4U32 X;  1P2M B;  2UUY B;  3P92 E;  1DTK A;  2CA7 A;  3BTQ I;  3AUE A;  1DTX A;  3AUG A;  2DDJ A;  1D0D A;  3BTF I;  3L3T E;  5JB7 A;  3BTM I;  3P95 E;  1B0C A;  1TAP A;  2FI5 I;  2RA3 C;  3D65 I;  3UIR C;  1BRC I;  1BF0 A;  1KUN A;  1MTN D;  1P2K I;  1BZ5 A;  1BRB I;  1D0D B;  4NTW B;  1YLD B;  2M99 A;  1BZX I;  3TGK I;  1KIG I;  3M7Q B;  2UUX A;  1P2N B;  2M01 A;  1UUA A;  1NAG A;  3BTK I;  1BIK A;  3UOU B;  2LFL A;  3OTJ I;  2DDI A;  1AAP A;  1BHC A;  4ISN B;  2ZVX A;  3LDI A;  1P2Q B;  1SHP A;  1BUN B;  1P2I I;  2FI3 I;  1T8M B;  3CI7 A;  4Y0Y I;  3TGI I;  1IRH A;  1BTH P;  3BYB A;  1P2J I;  2ZJX A;  1K6U A;  2JOT A;  3U1J E;  1BTI A;  4DTG K;  1P2O B;  3BTE I;  3LDJ A;  3BTH I;  1ADZ A;  1TOC R;  3AUH A;  3AUB A;  3AUC A;  4Y10 I;  2J6D A;  2IJO I;  1CA0 D;  1LD5 A;  1CO7 I;  1DEM A;  3AUI A;  3FP8 I;  3L33 E;  1BPT A;  4BNR I;  1JV9 A;  3BTW I;  4NTY B;  3WNY A;  3BTG I;  4ISO B;  4Y11 I;  5JB6 A;  4TPI I;  2KNT A;  5JB5 A;  1F5R I;  1FY8 I;  1ZJD B;  5PTI A;  1F7Z I;  1ZR0 B;  4WWY C;  4PTI A;  6PTI A;  4NTX B;  2KCR A;  1QLQ A;  9PTI A;  1BPI A;  4Y0Z I;  1YC0 I;  1TFX C;  3BTD I;  1CBW D;  1T8L B;  3FP6 I;  3GYM I;  1T8O B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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