2DDJA

Nmr structure of the second kunitz domain of human wfikkn1
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
70
structure length
70
Chain Sequence
EAEAEFTDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVVDHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords WAP, follistatin/kazal, immunoglobulin, kunitz and netrin do
total genus 15
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 2006-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 2ddjA00
2DDJA 1P2KI 1YC0I 1BIKA 1BPTA 2FTLI 3GYMI 1BPIA 1OA55 1CBWD 3AUIA 2UUXA 3T62D 4DG4C 1TAPA 3FP6I 1UUBA 2KCRA 1Y62A 4WXVC 1TOCR 1ZR0B 3AUGA 3P92E 1P2QB 3BTMI 8PTIA 3BTQI 2TPII 2CA7A 5JB7A 4NTWB 1T8LB 4BQDA 1OA65 3LDMA 1P2NB 2W8XA 2FI3I 3L33E 1YLDB 1T8NB 2J6DA 3D65I 3AUEA 1BZXI 1ZJDB 1JV8A 1BTIA 2M01A 3P95E 2HEXA 1DEMA 4WWYC 1CA0D 1KIGI 3FP7J 4U32X 1BTHP 3BTDI 1F7ZI 3TGII 1JC6A 1EJMB 1P2OB 4Y0YI 1TFXC 5JB5A 3BTEI 1T8MB 1BUNB 1BF0A 3WNYA 1DTKA 3BTHI 2PTCI 1T7CB 9PTIA 1G6XA 3L3TE 3OTJI 1BHCA 1FAKI 3BYBA 2TGPI 3BTFI 1LD5A 5PTIA 1PITA 1KTHA 2KAII 2JOTA 3CI7A 4ISLB 4NTYB 1TAWB 1KUNA 1ADZA 4ISOB 1MTND 1P2JI 1FANA 3M7QB 1JV9A 3AUDA 1NAGA 1B0CA 2LFLA 3AUHA 3TGKI 1DTXA 4PTIA 1YKTB 4U30W 2IJOI 4Y11I 3UIRC 2R9PE 1CO7I 1BRCI 1F5RI 1LD6A 1BZ5A 3LDJA 3BTTI 2LFKA 3BTGI 1D0DA 1T8OB 4BD9B 3LDIA 1YLCB 4ISNB 1DENA 6PTIA 4NTXB 1KNTA 3BTKI 2FI4I 3OFWA 1FY8I 4Y10I 2DDIA 3FP8I 1TPAI 1P2II 2FI5I 2ZJXA 3BTWI 1BRBI 1EAWB 4Y0ZI 1K6UA 5JB4A 1IRHA 2RA3C 5JB6A 3U1JE 2UUYB 4DTGK 2FTMB 5C67C 7PTIA 4TPII 3TPII 3AUBA 2ODYE 1AAPA 1TCPA 3TGJI 3UOUB 1AALA 2ZVXA 3AUCA 2M99A 4BNRI 1UUAA 1P2MB 1D0DB 1QLQA 1SHPA 2KNTA
chains in the Genus database with same CATH superfamily
2DDJA 1P2KI 1YC0I 1BIKA 1BPTA 2FTLI 3GYMI 1BPIA 1OA55 1CBWD 3AUIA 2UUXA 3T62D 4DG4C 1TAPA 3FP6I 1UUBA 2KCRA 1Y62A 4WXVC 1TOCR 1ZR0B 3AUGA 3P92E 1P2QB 3BTMI 8PTIA 3BTQI 2TPII 2CA7A 5JB7A 4NTWB 1T8LB 4BQDA 1OA65 3LDMA 1P2NB 2W8XA 2FI3I 3L33E 1YLDB 1T8NB 2J6DA 3D65I 3AUEA 1BZXI 1ZJDB 1JV8A 1BTIA 2M01A 3P95E 2HEXA 1DEMA 4WWYC 1CA0D 1KIGI 3FP7J 4U32X 1BTHP 3BTDI 1F7ZI 3TGII 1JC6A 1EJMB 1P2OB 4Y0YI 1TFXC 5JB5A 3BTEI 1T8MB 1BUNB 1BF0A 3WNYA 1DTKA 3BTHI 2PTCI 1T7CB 9PTIA 1G6XA 3L3TE 3OTJI 1BHCA 1FAKI 3BYBA 2TGPI 3BTFI 1LD5A 5PTIA 1PITA 1KTHA 2KAII 2JOTA 3CI7A 4ISLB 4NTYB 1TAWB 1KUNA 1ADZA 4ISOB 1MTND 1P2JI 1FANA 3M7QB 1JV9A 3AUDA 1NAGA 1B0CA 2LFLA 3AUHA 3TGKI 1DTXA 4PTIA 1YKTB 4U30W 2IJOI 4Y11I 3UIRC 2R9PE 1CO7I 1BRCI 1F5RI 1LD6A 1BZ5A 3LDJA 3BTTI 2LFKA 3BTGI 1D0DA 1T8OB 4BD9B 3LDIA 1YLCB 4ISNB 1DENA 6PTIA 4NTXB 1KNTA 3BTKI 2FI4I 3OFWA 1FY8I 4Y10I 2DDIA 3FP8I 1TPAI 1P2II 2FI5I 2ZJXA 3BTWI 1BRBI 1EAWB 4Y0ZI 1K6UA 5JB4A 1IRHA 2RA3C 5JB6A 3U1JE 2UUYB 4DTGK 2FTMB 5C67C 7PTIA 4TPII 3TPII 3AUBA 2ODYE 1AAPA 1TCPA 3TGJI 3UOUB 1AALA 2ZVXA 3AUCA 2M99A 4BNRI 1UUAA 1P2MB 1D0DB 1QLQA 1SHPA 2KNTA
chains in the Genus database with same CATH topology
2DDJA 1P2KI 1YC0I 1BIKA 1BPTA 2FTLI 3GYMI 1BPIA 1OA55 1CBWD 3AUIA 2UUXA 3T62D 4DG4C 1TAPA 3FP6I 1UUBA 2KCRA 1Y62A 4WXVC 1TOCR 1ZR0B 3AUGA 3P92E 1P2QB 3BTMI 8PTIA 3BTQI 2TPII 2CA7A 5JB7A 4NTWB 1T8LB 4BQDA 1OA65 3LDMA 1P2NB 2W8XA 2FI3I 3L33E 1YLDB 1T8NB 2J6DA 3D65I 3AUEA 1BZXI 1ZJDB 1JV8A 1BTIA 2M01A 3P95E 2HEXA 1DEMA 4WWYC 1CA0D 1KIGI 3FP7J 4U32X 1BTHP 3BTDI 1F7ZI 3TGII 1JC6A 1EJMB 1P2OB 4Y0YI 1TFXC 5JB5A 3BTEI 1T8MB 1BUNB 1BF0A 3WNYA 1DTKA 3BTHI 2PTCI 1T7CB 9PTIA 1G6XA 3L3TE 3OTJI 1BHCA 1FAKI 3BYBA 2TGPI 3BTFI 1LD5A 5PTIA 1PITA 1KTHA 2KAII 2JOTA 3CI7A 4ISLB 4NTYB 1TAWB 1KUNA 1ADZA 4ISOB 1MTND 1P2JI 1FANA 3M7QB 1JV9A 3AUDA 1NAGA 1B0CA 2LFLA 3AUHA 3TGKI 1DTXA 4PTIA 1YKTB 4U30W 2IJOI 4Y11I 3UIRC 2R9PE 1CO7I 1BRCI 1F5RI 1LD6A 1BZ5A 3LDJA 3BTTI 2LFKA 3BTGI 1D0DA 1T8OB 4BD9B 3LDIA 1YLCB 4ISNB 1DENA 6PTIA 4NTXB 1KNTA 3BTKI 2FI4I 3OFWA 1FY8I 4Y10I 2DDIA 3FP8I 1TPAI 1P2II 2FI5I 2ZJXA 3BTWI 1BRBI 1EAWB 4Y0ZI 1K6UA 5JB4A 1IRHA 2RA3C 5JB6A 3U1JE 2UUYB 4DTGK 2FTMB 5C67C 7PTIA 4TPII 3TPII 3AUBA 2ODYE 1AAPA 1TCPA 3TGJI 3UOUB 1AALA 2ZVXA 3AUCA 2M99A 4BNRI 1UUAA 1P2MB 1D0DB 1QLQA 1SHPA 2KNTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DDJ A;  1P2K I;  1YC0 I;  1BIK A;  1BPT A;  2FTL I;  3GYM I;  1BPI A;  1OA5 5;  1CBW D;  3AUI A;  2UUX A;  3T62 D;  4DG4 C;  1TAP A;  3FP6 I;  1UUB A;  2KCR A;  1Y62 A;  4WXV C;  1TOC R;  1ZR0 B;  3AUG A;  3P92 E;  1P2Q B;  3BTM I;  8PTI A;  3BTQ I;  2TPI I;  2CA7 A;  5JB7 A;  4NTW B;  1T8L B;  4BQD A;  1OA6 5;  3LDM A;  1P2N B;  2W8X A;  2FI3 I;  3L33 E;  1YLD B;  1T8N B;  2J6D A;  3D65 I;  3AUE A;  1BZX I;  1ZJD B;  1JV8 A;  1BTI A;  2M01 A;  3P95 E;  2HEX A;  1DEM A;  4WWY C;  1CA0 D;  1KIG I;  3FP7 J;  4U32 X;  1BTH P;  3BTD I;  1F7Z I;  3TGI I;  1JC6 A;  1EJM B;  1P2O B;  4Y0Y I;  1TFX C;  5JB5 A;  3BTE I;  1T8M B;  1BUN B;  1BF0 A;  3WNY A;  1DTK A;  3BTH I;  2PTC I;  1T7C B;  9PTI A;  1G6X A;  3L3T E;  3OTJ I;  1BHC A;  1FAK I;  3BYB A;  2TGP I;  3BTF I;  1LD5 A;  5PTI A;  1PIT A;  1KTH A;  2KAI I;  2JOT A;  3CI7 A;  4ISL B;  4NTY B;  1TAW B;  1KUN A;  1ADZ A;  4ISO B;  1MTN D;  1P2J I;  1FAN A;  3M7Q B;  1JV9 A;  3AUD A;  1NAG A;  1B0C A;  2LFL A;  3AUH A;  3TGK I;  1DTX A;  4PTI A;  1YKT B;  4U30 W;  2IJO I;  4Y11 I;  3UIR C;  2R9P E;  1CO7 I;  1BRC I;  1F5R I;  1LD6 A;  1BZ5 A;  3LDJ A;  3BTT I;  2LFK A;  3BTG I;  1D0D A;  1T8O B;  4BD9 B;  3LDI A;  1YLC B;  4ISN B;  1DEN A;  6PTI A;  4NTX B;  1KNT A;  3BTK I;  2FI4 I;  3OFW A;  1FY8 I;  4Y10 I;  2DDI A;  3FP8 I;  1TPA I;  1P2I I;  2FI5 I;  2ZJX A;  3BTW I;  1BRB I;  1EAW B;  4Y0Z I;  1K6U A;  5JB4 A;  1IRH A;  2RA3 C;  5JB6 A;  3U1J E;  2UUY B;  4DTG K;  2FTM B;  5C67 C;  7PTI A;  4TPI I;  3TPI I;  3AUB A;  2ODY E;  1AAP A;  1TCP A;  3TGJ I;  3UOU B;  1AAL A;  2ZVX A;  3AUC A;  2M99 A;  4BNR I;  1UUA A;  1P2M B;  1D0D B;  1QLQ A;  1SHP A;  2KNT A; 
#chains in the Genus database with same CATH topology
 2DDJ A;  1P2K I;  1YC0 I;  1BIK A;  1BPT A;  2FTL I;  3GYM I;  1BPI A;  1OA5 5;  1CBW D;  3AUI A;  2UUX A;  3T62 D;  4DG4 C;  1TAP A;  3FP6 I;  1UUB A;  2KCR A;  1Y62 A;  4WXV C;  1TOC R;  1ZR0 B;  3AUG A;  3P92 E;  1P2Q B;  3BTM I;  8PTI A;  3BTQ I;  2TPI I;  2CA7 A;  5JB7 A;  4NTW B;  1T8L B;  4BQD A;  1OA6 5;  3LDM A;  1P2N B;  2W8X A;  2FI3 I;  3L33 E;  1YLD B;  1T8N B;  2J6D A;  3D65 I;  3AUE A;  1BZX I;  1ZJD B;  1JV8 A;  1BTI A;  2M01 A;  3P95 E;  2HEX A;  1DEM A;  4WWY C;  1CA0 D;  1KIG I;  3FP7 J;  4U32 X;  1BTH P;  3BTD I;  1F7Z I;  3TGI I;  1JC6 A;  1EJM B;  1P2O B;  4Y0Y I;  1TFX C;  5JB5 A;  3BTE I;  1T8M B;  1BUN B;  1BF0 A;  3WNY A;  1DTK A;  3BTH I;  2PTC I;  1T7C B;  9PTI A;  1G6X A;  3L3T E;  3OTJ I;  1BHC A;  1FAK I;  3BYB A;  2TGP I;  3BTF I;  1LD5 A;  5PTI A;  1PIT A;  1KTH A;  2KAI I;  2JOT A;  3CI7 A;  4ISL B;  4NTY B;  1TAW B;  1KUN A;  1ADZ A;  4ISO B;  1MTN D;  1P2J I;  1FAN A;  3M7Q B;  1JV9 A;  3AUD A;  1NAG A;  1B0C A;  2LFL A;  3AUH A;  3TGK I;  1DTX A;  4PTI A;  1YKT B;  4U30 W;  2IJO I;  4Y11 I;  3UIR C;  2R9P E;  1CO7 I;  1BRC I;  1F5R I;  1LD6 A;  1BZ5 A;  3LDJ A;  3BTT I;  2LFK A;  3BTG I;  1D0D A;  1T8O B;  4BD9 B;  3LDI A;  1YLC B;  4ISN B;  1DEN A;  6PTI A;  4NTX B;  1KNT A;  3BTK I;  2FI4 I;  3OFW A;  1FY8 I;  4Y10 I;  2DDI A;  3FP8 I;  1TPA I;  1P2I I;  2FI5 I;  2ZJX A;  3BTW I;  1BRB I;  1EAW B;  4Y0Z I;  1K6U A;  5JB4 A;  1IRH A;  2RA3 C;  5JB6 A;  3U1J E;  2UUY B;  4DTG K;  2FTM B;  5C67 C;  7PTI A;  4TPI I;  3TPI I;  3AUB A;  2ODY E;  1AAP A;  1TCP A;  3TGJ I;  3UOU B;  1AAL A;  2ZVX A;  3AUC A;  2M99 A;  4BNR I;  1UUA A;  1P2M B;  1D0D B;  1QLQ A;  1SHP A;  2KNT A; 
#chains in the Genus database with same CATH homology
 2DDJ A;  1P2K I;  1YC0 I;  1BIK A;  1BPT A;  2FTL I;  3GYM I;  1BPI A;  1OA5 5;  1CBW D;  3AUI A;  2UUX A;  3T62 D;  4DG4 C;  1TAP A;  3FP6 I;  1UUB A;  2KCR A;  1Y62 A;  4WXV C;  1TOC R;  1ZR0 B;  3AUG A;  3P92 E;  1P2Q B;  3BTM I;  8PTI A;  3BTQ I;  2TPI I;  2CA7 A;  5JB7 A;  4NTW B;  1T8L B;  4BQD A;  1OA6 5;  3LDM A;  1P2N B;  2W8X A;  2FI3 I;  3L33 E;  1YLD B;  1T8N B;  2J6D A;  3D65 I;  3AUE A;  1BZX I;  1ZJD B;  1JV8 A;  1BTI A;  2M01 A;  3P95 E;  2HEX A;  1DEM A;  4WWY C;  1CA0 D;  1KIG I;  3FP7 J;  4U32 X;  1BTH P;  3BTD I;  1F7Z I;  3TGI I;  1JC6 A;  1EJM B;  1P2O B;  4Y0Y I;  1TFX C;  5JB5 A;  3BTE I;  1T8M B;  1BUN B;  1BF0 A;  3WNY A;  1DTK A;  3BTH I;  2PTC I;  1T7C B;  9PTI A;  1G6X A;  3L3T E;  3OTJ I;  1BHC A;  1FAK I;  3BYB A;  2TGP I;  3BTF I;  1LD5 A;  5PTI A;  1PIT A;  1KTH A;  2KAI I;  2JOT A;  3CI7 A;  4ISL B;  4NTY B;  1TAW B;  1KUN A;  1ADZ A;  4ISO B;  1MTN D;  1P2J I;  1FAN A;  3M7Q B;  1JV9 A;  3AUD A;  1NAG A;  1B0C A;  2LFL A;  3AUH A;  3TGK I;  1DTX A;  4PTI A;  1YKT B;  4U30 W;  2IJO I;  4Y11 I;  3UIR C;  2R9P E;  1CO7 I;  1BRC I;  1F5R I;  1LD6 A;  1BZ5 A;  3LDJ A;  3BTT I;  2LFK A;  3BTG I;  1D0D A;  1T8O B;  4BD9 B;  3LDI A;  1YLC B;  4ISN B;  1DEN A;  6PTI A;  4NTX B;  1KNT A;  3BTK I;  2FI4 I;  3OFW A;  1FY8 I;  4Y10 I;  2DDI A;  3FP8 I;  1TPA I;  1P2I I;  2FI5 I;  2ZJX A;  3BTW I;  1BRB I;  1EAW B;  4Y0Z I;  1K6U A;  5JB4 A;  1IRH A;  2RA3 C;  5JB6 A;  3U1J E;  2UUY B;  4DTG K;  2FTM B;  5C67 C;  7PTI A;  4TPI I;  3TPI I;  3AUB A;  2ODY E;  1AAP A;  1TCP A;  3TGJ I;  3UOU B;  1AAL A;  2ZVX A;  3AUC A;  2M99 A;  4BNR I;  1UUA A;  1P2M B;  1D0D B;  1QLQ A;  1SHP A;  2KNT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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