2GF1A

Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
70
structure length
70
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Growth factor
molecule keywords INSULIN-LIKE GROWTH FACTOR I
publication title Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study.
pubmed doi rcsb
source organism Homo sapiens
total genus 24
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 1991-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 2gf1A00
3KR3D 2DSQC 3GF1A 1IMXA 1B9GA 1H02B 1PMXA 2DSPI 2L29B 3LRIA 1EFEA 1GZYB 2JZQA 1GZRB 5L3NA 5L3LA 2KJIA 2DSRI 1BQTA 2LWZA 1TGRA 6INSE 1SJUA 1GZZB 1ZEIA 1WQJI 2KQPA 4XSSB 5L3MA 1IGLA 1H59A 2GF1A
chains in the Genus database with same CATH superfamily
3KR3D 2DSQC 3GF1A 1IMXA 1B9GA 1H02B 1PMXA 2DSPI 2L29B 3LRIA 1EFEA 1GZYB 2JZQA 1GZRB 5L3NA 5L3LA 2KJIA 2DSRI 1BQTA 2LWZA 1TGRA 6INSE 3F2DA 3F2CA 1SJUA 1GZZB 1ZEIA 1WQJI 2KQPA 2L14B 4XSSB 5L3MA 1IGLA 3F2BA 1H59A 2GF1A
chains in the Genus database with same CATH topology
3KR3D 2DSQC 3GF1A 1IMXA 1B9GA 1H02B 1PMXA 2DSPI 2L29B 3LRIA 1EFEA 1GZYB 2JZQA 1GZRB 5L3NA 5L3LA 2KJIA 2DSRI 1BQTA 2LWZA 1TGRA 6INSE 1SJUA 1GZZB 1ZEIA 1WQJI 2KQPA 4XSSB 5L3MA 1IGLA 1H59A 2GF1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KR3 D;  2DSQ C;  3GF1 A;  1IMX A;  1B9G A;  1H02 B;  1PMX A;  2DSP I;  2L29 B;  3LRI A;  1EFE A;  1GZY B;  2JZQ A;  1GZR B;  5L3N A;  5L3L A;  2KJI A;  2DSR I;  1BQT A;  2LWZ A;  1TGR A;  6INS E;  1SJU A;  1GZZ B;  1ZEI A;  1WQJ I;  2KQP A;  4XSS B;  5L3M A;  1IGL A;  1H59 A;  2GF1 A; 
#chains in the Genus database with same CATH topology
 3KR3 D;  2DSQ C;  3GF1 A;  1IMX A;  1B9G A;  1H02 B;  1PMX A;  2DSP I;  2L29 B;  3LRI A;  1EFE A;  1GZY B;  2JZQ A;  1GZR B;  5L3N A;  5L3L A;  2KJI A;  2DSR I;  1BQT A;  2LWZ A;  1TGR A;  6INS E;  3F2D A;  3F2C A;  1SJU A;  1GZZ B;  1ZEI A;  1WQJ I;  2KQP A;  2L14 B;  4XSS B;  5L3M A;  1IGL A;  3F2B A;  1H59 A;  2GF1 A; 
#chains in the Genus database with same CATH homology
 3KR3 D;  2DSQ C;  3GF1 A;  1IMX A;  1B9G A;  1H02 B;  1PMX A;  2DSP I;  2L29 B;  3LRI A;  1EFE A;  1GZY B;  2JZQ A;  1GZR B;  5L3N A;  5L3L A;  2KJI A;  2DSR I;  1BQT A;  2LWZ A;  1TGR A;  6INS E;  1SJU A;  1GZZ B;  1ZEI A;  1WQJ I;  2KQP A;  4XSS B;  5L3M A;  1IGL A;  1H59 A;  2GF1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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