2GU7A

E. coli methionine aminopeptidase unliganded, 1:0.5
Total Genus 80
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
261
structure length
261
Chain Sequence
SIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Structural basis of catalysis by monometalated methionine aminopeptidase.
pubmed doi rcsb
source organism Escherichia coli
total genus 80
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2006-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2gu7A00
1C24A 3PKCA 1WN1A 3TAVA 2BWSA 4QR8A 1N51A 4U1BA 4IDYA 2V3ZA 4U70A 2Q8KA 4U75A 5D6FA 2BWYA 3IU8A 3MATA 3L24A 4U73A 1W2MA 2ADUA 4FLJA 1WLRA 4IU6A 1CHMA 2V3XA 5CNXA 4ZWUA 1QZYA 3CB5A 4PV4A 2B3KA 3BIPA 4FO8A 2Q93A 4HXXA 2Q95A 1KQ0A 2ZSGA 1WL6A 3FMQA 4U6EA 4U6CA 2EVMA 3FM3A 5CIKA 4IKRA 2GU5A 1XGMA 1QXZA 4FKCA 1C21A 1MATA 3FMRA 4IKSA 2GG9A 2B3LA 2EA4A 2GU7A 2HOWA 2P9AA 2GU6A 3IU9A 2Q96A 1KP0A 2BWUA 2P99A 3PKEA 3PKBA 5CDEA 2IW2A 3RVAA 2BHCA 1JAWA 2BH3A 2BN7A 2V6CA 5FCHA 2OAZA 5CLSA 2B3HA 4IPAA 2NQ6A 5FCFA 2GG0A 1XNZA 5JHUA 2GG5A 2GG8A 1WBQA 4FUKA 1XGSA 4S01A 4B28A 3CTZA 2BWTA 1XGOA 1YJ3A 2GGBA 5JFRA 5JI6A 2GU4A 4U6WA 1QXWA 4A6WA 2BHBA 2EVOA 4FLIA 4FO7A 3CB6A 2GG2A 3S6BA 1BOAA 2GG7A 2GG3A 3TB5A 1QXYA 2GGCA 4U6JA 4ZWPA 1C22A 2GZ5A 4FLKA 2P98A 1XGNA 5CDLA 2BWWA 4Z7MA 4U69A 1R5HA 3MX6A 4S00A 1YW7A 2NQ7A 4RZYA 2MATA 4RGZ1 2GTXA 3Q6DA 1WKMA 2EVCA 5CDVA 3PKAA 4U76A 1PV9A 5CE6A 4ZNGA 4KM3A 4RZZA 1O0XA 1Y1NA 2BWXA 2GA2A 4IKTA 4R60A 1WL9A 2OKNA 5E5BA 4JUQA 3PKDA 4PNCA 4IKUA 4U6ZA 3RORA 4A6VA 1R5GA 4IECA 3IU7A 4IF7A 2Q92A 4OOKA 2BHDA 4FLLA 3BIQA 2G6PA 3MR1A 3D27A 4ZWOA 2V3YA 1C27A 1YVMA 1R58A 2BWVA 1YW9A 2EA2A 3BITA 3IG4A 1WY2A 1C23A 2DFIA 2BHAA 1B6AA 4S2TP 5D6EA 1YW8A 1BN5A 1M35A 1B59A 1W7VA 4MATA 4U71A 4EGEA 1A16A 2Q94A 4S2RP 2BB7A 1KQ9A 3L7GA
chains in the Genus database with same CATH superfamily
1C24A 3PKCA 1WN1A 3TAVA 2BWSA 4QR8A 1N51A 4U1BA 4IDYA 2V3ZA 4U70A 2Q8KA 4U75A 5D6FA 2BWYA 3IU8A 3MATA 3L24A 4U73A 1W2MA 2ADUA 4FLJA 1WLRA 4IU6A 1CHMA 2V3XA 5CNXA 4ZWUA 1QZYA 3CB5A 4PV4A 2B3KA 3BIPA 4FO8A 2Q93A 4HXXA 2Q95A 1KQ0A 2ZSGA 1WL6A 3FMQA 4U6EA 4U6CA 2EVMA 3FM3A 5CIKA 4IKRA 2GU5A 1XGMA 1QXZA 4FKCA 1C21A 1MATA 3FMRA 4IKSA 2GG9A 2B3LA 2EA4A 2GU7A 2HOWA 2P9AA 2GU6A 3IU9A 2Q96A 1KP0A 2BWUA 2P99A 3PKEA 3PKBA 5CDEA 2IW2A 3RVAA 2BHCA 1JAWA 2BH3A 2BN7A 2V6CA 5FCHA 2OAZA 5CLSA 2B3HA 4IPAA 2NQ6A 5FCFA 2GG0A 1XNZA 5JHUA 2GG5A 2GG8A 1WBQA 4FUKA 1XGSA 4S01A 4B28A 3CTZA 2BWTA 1XGOA 1YJ3A 2GGBA 5JFRA 5JI6A 2GU4A 4U6WA 1QXWA 4A6WA 2BHBA 2EVOA 4FLIA 4FO7A 3CB6A 2GG2A 3S6BA 1BOAA 2GG7A 2GG3A 3TB5A 1QXYA 2GGCA 4U6JA 4ZWPA 1C22A 2GZ5A 4FLKA 2P98A 1XGNA 5CDLA 2BWWA 4Z7MA 4U69A 1R5HA 3MX6A 4S00A 1YW7A 2NQ7A 4RZYA 2MATA 4RGZ1 2GTXA 3Q6DA 1WKMA 2EVCA 5CDVA 3PKAA 4U76A 1PV9A 5CE6A 4ZNGA 4KM3A 4RZZA 1O0XA 1Y1NA 2BWXA 2GA2A 4IKTA 4R60A 1WL9A 2OKNA 5E5BA 4JUQA 3PKDA 4PNCA 4IKUA 4U6ZA 3RORA 4A6VA 1R5GA 4IECA 3IU7A 4IF7A 2Q92A 4OOKA 2BHDA 4FLLA 3BIQA 2G6PA 3MR1A 3D27A 4ZWOA 2V3YA 1C27A 1YVMA 1R58A 2BWVA 1YW9A 2EA2A 3BITA 3IG4A 1WY2A 1C23A 2DFIA 2BHAA 1B6AA 4S2TP 5D6EA 1YW8A 1BN5A 1M35A 1B59A 1W7VA 4MATA 4U71A 4EGEA 1A16A 2Q94A 4S2RP 2BB7A 1KQ9A 3L7GA
chains in the Genus database with same CATH topology
1C24A 3PKCA 1WN1A 3TAVA 2BWSA 4QR8A 1N51A 4U1BA 4IDYA 2V3ZA 4U70A 2Q8KA 4U75A 5D6FA 2BWYA 3IU8A 3MATA 3L24A 4U73A 1W2MA 2ADUA 4FLJA 1WLRA 4IU6A 1CHMA 2V3XA 5CNXA 4ZWUA 1QZYA 3CB5A 4PV4A 2B3KA 3BIPA 4FO8A 2Q93A 4HXXA 2Q95A 1KQ0A 2ZSGA 1WL6A 3FMQA 4U6EA 4U6CA 2EVMA 3FM3A 5CIKA 4IKRA 2GU5A 1XGMA 1QXZA 4FKCA 1C21A 1MATA 3FMRA 4IKSA 2GG9A 2B3LA 2EA4A 2GU7A 2HOWA 2P9AA 2GU6A 3IU9A 2Q96A 1KP0A 2BWUA 2P99A 3PKEA 3PKBA 5CDEA 2IW2A 3RVAA 2BHCA 1JAWA 2BH3A 2BN7A 2V6CA 5FCHA 2OAZA 5CLSA 2B3HA 4IPAA 2NQ6A 5FCFA 2GG0A 1XNZA 5JHUA 2GG5A 2GG8A 1WBQA 4FUKA 1XGSA 4S01A 4B28A 3CTZA 2BWTA 1XGOA 1YJ3A 2GGBA 5JFRA 5JI6A 2GU4A 4U6WA 1QXWA 4A6WA 2BHBA 2EVOA 4FLIA 4FO7A 3CB6A 2GG2A 3S6BA 1BOAA 2GG7A 2GG3A 3TB5A 1QXYA 2GGCA 4U6JA 4ZWPA 1C22A 2GZ5A 4FLKA 2P98A 1XGNA 5CDLA 2BWWA 4Z7MA 4U69A 1R5HA 3MX6A 4S00A 1YW7A 2NQ7A 4RZYA 2MATA 4RGZ1 2GTXA 3Q6DA 1WKMA 2EVCA 5CDVA 3PKAA 4U76A 1PV9A 5CE6A 4ZNGA 4KM3A 4RZZA 1O0XA 1Y1NA 2BWXA 2GA2A 4IKTA 4R60A 1WL9A 2OKNA 5E5BA 4JUQA 3PKDA 4PNCA 4IKUA 4U6ZA 3RORA 4A6VA 1R5GA 4IECA 3IU7A 4IF7A 2Q92A 4OOKA 2BHDA 4FLLA 3BIQA 2G6PA 3MR1A 3D27A 4ZWOA 2V3YA 1C27A 1YVMA 1R58A 2BWVA 1YW9A 2EA2A 3BITA 3IG4A 1WY2A 1C23A 2DFIA 2BHAA 1B6AA 4S2TP 5D6EA 1YW8A 1BN5A 1M35A 1B59A 1W7VA 4MATA 4U71A 4EGEA 1A16A 2Q94A 4S2RP 2BB7A 1KQ9A 3L7GA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1C24 A;  3PKC A;  1WN1 A;  3TAV A;  2BWS A;  4QR8 A;  1N51 A;  4U1B A;  4IDY A;  2V3Z A;  4U70 A;  2Q8K A;  4U75 A;  5D6F A;  2BWY A;  3IU8 A;  3MAT A;  3L24 A;  4U73 A;  1W2M A;  2ADU A;  4FLJ A;  1WLR A;  4IU6 A;  1CHM A;  2V3X A;  5CNX A;  4ZWU A;  1QZY A;  3CB5 A;  4PV4 A;  2B3K A;  3BIP A;  4FO8 A;  2Q93 A;  4HXX A;  2Q95 A;  1KQ0 A;  2ZSG A;  1WL6 A;  3FMQ A;  4U6E A;  4U6C A;  2EVM A;  3FM3 A;  5CIK A;  4IKR A;  2GU5 A;  1XGM A;  1QXZ A;  4FKC A;  1C21 A;  1MAT A;  3FMR A;  4IKS A;  2GG9 A;  2B3L A;  2EA4 A;  2GU7 A;  2HOW A;  2P9A A;  2GU6 A;  3IU9 A;  2Q96 A;  1KP0 A;  2BWU A;  2P99 A;  3PKE A;  3PKB A;  5CDE A;  2IW2 A;  3RVA A;  2BHC A;  1JAW A;  2BH3 A;  2BN7 A;  2V6C A;  5FCH A;  2OAZ A;  5CLS A;  2B3H A;  4IPA A;  2NQ6 A;  5FCF A;  2GG0 A;  1XNZ A;  5JHU A;  2GG5 A;  2GG8 A;  1WBQ A;  4FUK A;  1XGS A;  4S01 A;  4B28 A;  3CTZ A;  2BWT A;  1XGO A;  1YJ3 A;  2GGB A;  5JFR A;  5JI6 A;  2GU4 A;  4U6W A;  1QXW A;  4A6W A;  2BHB A;  2EVO A;  4FLI A;  4FO7 A;  3CB6 A;  2GG2 A;  3S6B A;  1BOA A;  2GG7 A;  2GG3 A;  3TB5 A;  1QXY A;  2GGC A;  4U6J A;  4ZWP A;  1C22 A;  2GZ5 A;  4FLK A;  2P98 A;  1XGN A;  5CDL A;  2BWW A;  4Z7M A;  4U69 A;  1R5H A;  3MX6 A;  4S00 A;  1YW7 A;  2NQ7 A;  4RZY A;  2MAT A;  4RGZ 1;  2GTX A;  3Q6D A;  1WKM A;  2EVC A;  5CDV A;  3PKA A;  4U76 A;  1PV9 A;  5CE6 A;  4ZNG A;  4KM3 A;  4RZZ A;  1O0X A;  1Y1N A;  2BWX A;  2GA2 A;  4IKT A;  4R60 A;  1WL9 A;  2OKN A;  5E5B A;  4JUQ A;  3PKD A;  4PNC A;  4IKU A;  4U6Z A;  3ROR A;  4A6V A;  1R5G A;  4IEC A;  3IU7 A;  4IF7 A;  2Q92 A;  4OOK A;  2BHD A;  4FLL A;  3BIQ A;  2G6P A;  3MR1 A;  3D27 A;  4ZWO A;  2V3Y A;  1C27 A;  1YVM A;  1R58 A;  2BWV A;  1YW9 A;  2EA2 A;  3BIT A;  3IG4 A;  1WY2 A;  1C23 A;  2DFI A;  2BHA A;  1B6A A;  4S2T P;  5D6E A;  1YW8 A;  1BN5 A;  1M35 A;  1B59 A;  1W7V A;  4MAT A;  4U71 A;  4EGE A;  1A16 A;  2Q94 A;  4S2R P;  2BB7 A;  1KQ9 A;  3L7G A; 
#chains in the Genus database with same CATH topology
 1C24 A;  3PKC A;  1WN1 A;  3TAV A;  2BWS A;  4QR8 A;  1N51 A;  4U1B A;  4IDY A;  2V3Z A;  4U70 A;  2Q8K A;  4U75 A;  5D6F A;  2BWY A;  3IU8 A;  3MAT A;  3L24 A;  4U73 A;  1W2M A;  2ADU A;  4FLJ A;  1WLR A;  4IU6 A;  1CHM A;  2V3X A;  5CNX A;  4ZWU A;  1QZY A;  3CB5 A;  4PV4 A;  2B3K A;  3BIP A;  4FO8 A;  2Q93 A;  4HXX A;  2Q95 A;  1KQ0 A;  2ZSG A;  1WL6 A;  3FMQ A;  4U6E A;  4U6C A;  2EVM A;  3FM3 A;  5CIK A;  4IKR A;  2GU5 A;  1XGM A;  1QXZ A;  4FKC A;  1C21 A;  1MAT A;  3FMR A;  4IKS A;  2GG9 A;  2B3L A;  2EA4 A;  2GU7 A;  2HOW A;  2P9A A;  2GU6 A;  3IU9 A;  2Q96 A;  1KP0 A;  2BWU A;  2P99 A;  3PKE A;  3PKB A;  5CDE A;  2IW2 A;  3RVA A;  2BHC A;  1JAW A;  2BH3 A;  2BN7 A;  2V6C A;  5FCH A;  2OAZ A;  5CLS A;  2B3H A;  4IPA A;  2NQ6 A;  5FCF A;  2GG0 A;  1XNZ A;  5JHU A;  2GG5 A;  2GG8 A;  1WBQ A;  4FUK A;  1XGS A;  4S01 A;  4B28 A;  3CTZ A;  2BWT A;  1XGO A;  1YJ3 A;  2GGB A;  5JFR A;  5JI6 A;  2GU4 A;  4U6W A;  1QXW A;  4A6W A;  2BHB A;  2EVO A;  4FLI A;  4FO7 A;  3CB6 A;  2GG2 A;  3S6B A;  1BOA A;  2GG7 A;  2GG3 A;  3TB5 A;  1QXY A;  2GGC A;  4U6J A;  4ZWP A;  1C22 A;  2GZ5 A;  4FLK A;  2P98 A;  1XGN A;  5CDL A;  2BWW A;  4Z7M A;  4U69 A;  1R5H A;  3MX6 A;  4S00 A;  1YW7 A;  2NQ7 A;  4RZY A;  2MAT A;  4RGZ 1;  2GTX A;  3Q6D A;  1WKM A;  2EVC A;  5CDV A;  3PKA A;  4U76 A;  1PV9 A;  5CE6 A;  4ZNG A;  4KM3 A;  4RZZ A;  1O0X A;  1Y1N A;  2BWX A;  2GA2 A;  4IKT A;  4R60 A;  1WL9 A;  2OKN A;  5E5B A;  4JUQ A;  3PKD A;  4PNC A;  4IKU A;  4U6Z A;  3ROR A;  4A6V A;  1R5G A;  4IEC A;  3IU7 A;  4IF7 A;  2Q92 A;  4OOK A;  2BHD A;  4FLL A;  3BIQ A;  2G6P A;  3MR1 A;  3D27 A;  4ZWO A;  2V3Y A;  1C27 A;  1YVM A;  1R58 A;  2BWV A;  1YW9 A;  2EA2 A;  3BIT A;  3IG4 A;  1WY2 A;  1C23 A;  2DFI A;  2BHA A;  1B6A A;  4S2T P;  5D6E A;  1YW8 A;  1BN5 A;  1M35 A;  1B59 A;  1W7V A;  4MAT A;  4U71 A;  4EGE A;  1A16 A;  2Q94 A;  4S2R P;  2BB7 A;  1KQ9 A;  3L7G A; 
#chains in the Genus database with same CATH homology
 1C24 A;  3PKC A;  1WN1 A;  3TAV A;  2BWS A;  4QR8 A;  1N51 A;  4U1B A;  4IDY A;  2V3Z A;  4U70 A;  2Q8K A;  4U75 A;  5D6F A;  2BWY A;  3IU8 A;  3MAT A;  3L24 A;  4U73 A;  1W2M A;  2ADU A;  4FLJ A;  1WLR A;  4IU6 A;  1CHM A;  2V3X A;  5CNX A;  4ZWU A;  1QZY A;  3CB5 A;  4PV4 A;  2B3K A;  3BIP A;  4FO8 A;  2Q93 A;  4HXX A;  2Q95 A;  1KQ0 A;  2ZSG A;  1WL6 A;  3FMQ A;  4U6E A;  4U6C A;  2EVM A;  3FM3 A;  5CIK A;  4IKR A;  2GU5 A;  1XGM A;  1QXZ A;  4FKC A;  1C21 A;  1MAT A;  3FMR A;  4IKS A;  2GG9 A;  2B3L A;  2EA4 A;  2GU7 A;  2HOW A;  2P9A A;  2GU6 A;  3IU9 A;  2Q96 A;  1KP0 A;  2BWU A;  2P99 A;  3PKE A;  3PKB A;  5CDE A;  2IW2 A;  3RVA A;  2BHC A;  1JAW A;  2BH3 A;  2BN7 A;  2V6C A;  5FCH A;  2OAZ A;  5CLS A;  2B3H A;  4IPA A;  2NQ6 A;  5FCF A;  2GG0 A;  1XNZ A;  5JHU A;  2GG5 A;  2GG8 A;  1WBQ A;  4FUK A;  1XGS A;  4S01 A;  4B28 A;  3CTZ A;  2BWT A;  1XGO A;  1YJ3 A;  2GGB A;  5JFR A;  5JI6 A;  2GU4 A;  4U6W A;  1QXW A;  4A6W A;  2BHB A;  2EVO A;  4FLI A;  4FO7 A;  3CB6 A;  2GG2 A;  3S6B A;  1BOA A;  2GG7 A;  2GG3 A;  3TB5 A;  1QXY A;  2GGC A;  4U6J A;  4ZWP A;  1C22 A;  2GZ5 A;  4FLK A;  2P98 A;  1XGN A;  5CDL A;  2BWW A;  4Z7M A;  4U69 A;  1R5H A;  3MX6 A;  4S00 A;  1YW7 A;  2NQ7 A;  4RZY A;  2MAT A;  4RGZ 1;  2GTX A;  3Q6D A;  1WKM A;  2EVC A;  5CDV A;  3PKA A;  4U76 A;  1PV9 A;  5CE6 A;  4ZNG A;  4KM3 A;  4RZZ A;  1O0X A;  1Y1N A;  2BWX A;  2GA2 A;  4IKT A;  4R60 A;  1WL9 A;  2OKN A;  5E5B A;  4JUQ A;  3PKD A;  4PNC A;  4IKU A;  4U6Z A;  3ROR A;  4A6V A;  1R5G A;  4IEC A;  3IU7 A;  4IF7 A;  2Q92 A;  4OOK A;  2BHD A;  4FLL A;  3BIQ A;  2G6P A;  3MR1 A;  3D27 A;  4ZWO A;  2V3Y A;  1C27 A;  1YVM A;  1R58 A;  2BWV A;  1YW9 A;  2EA2 A;  3BIT A;  3IG4 A;  1WY2 A;  1C23 A;  2DFI A;  2BHA A;  1B6A A;  4S2T P;  5D6E A;  1YW8 A;  1BN5 A;  1M35 A;  1B59 A;  1W7V A;  4MAT A;  4U71 A;  4EGE A;  1A16 A;  2Q94 A;  4S2R P;  2BB7 A;  1KQ9 A;  3L7G A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite