2H7EA

Solution structure of the talin f3 domain in complex with a chimeric beta3 integrin-pip kinase peptide- minimized average structure
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
101
structure length
101
Chain Sequence
PLGSGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of integrin activation by talin
pubmed doi rcsb
molecule tags Structural protein
source organism Gallus gallus
molecule keywords Talin-1
total genus 17
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2006-06-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2h7eA00
2DHKA 4ZRKA 5C5BB 2ZPYA 2DKQA 3ODWA 3QWMA 4WVFB 3PVWA 3P6AA 1W1DA 2J59M 1M7RA 3SUZA 2LYDA 3KY9A 1MKEA 1WJMA 2DX1A 4HDQA 4K17A 2BCJA 2Z0PA 1OY2A 2RSGA 3SO6A 1DBHA 2D9WA 5JLJB 2MFQA 1DDMA 4EKUA 2L1CA 3VOQA 2CY4A 2YT0A 5KCVA 5DHAB 1FAOA 2YVCA 1SHCA 3PG7A 4GXBA 4HAXB 3UZTA 3DXEA 4C0AA 5DI9B 2CODA 3AU5A 3KRWA 3TCAA 3ZDTA 1W1HA 1BWNA 2D9YA 2IFSA 3HK0A 1XR0B 1J0WA 4HB0B 2D2QA 1K5DB 1XX0A 2ELBA 3HW2B 2MDXA 1E5WA 4F7UP 1FGZA 1MIXA 2DHIA 1XODA 4H8SA 2VKIA 5J3YA 1RJ2A 5C5BA 2LG1A 4NY0A 2I1JA 5J3QA 1BTKA 3F0WA 2D9ZA 3SYXA 1DROA 5LONB 3DXCA 4BBKA 1I2HA 2NZ8B 2YS3A 2DTCA 2DA0A 3QIJA 2COCA 2DLWA 2K2UA 1DYNA 4PNKA 1EF1A 3PZDA 1M7EA 1XKEA 2E2XA 3PEGA 2EJ8A 2DYNA 4KVGB 1RRPB 1FGYA 1AWEA 3G9WA 1UNQA 5DHFB 3PVUA 3AJ4A 4F7GA 4K2PA 3TW1A 4F7HA 3GYPA 4GZUA 1NU2A 1WG7A 4B6HA 2GJYA 2OQBA 3A98B 3M1IB 3TFMA 4ZRIA 1NTVA 2D9XA 1P5TA 1PLSA 2W2XD 4WSFA 1UPQA 5FI0A 1UNRA 3AU4A 2Z0OA 4L6EA 3ODOA 3PSCA 3U7DA 2ROZB 4YL8A 4A6KA 2KGXB 2EC1A 2EMSA 2RVBB 4D0NB 1H4RA 2GCLA 1EGXA 3QBVB 4K81A 2H7EA 1N3HA 1I7AA 2AEHA 1X86A 2CAYA 1MAIA 1MPHA 2QKLA 4IOYX 5C6RA 4HATB 1ZM0A 1LB1A 2Y8FA 3WA0A 4ZRJA 5HE2A 1GC6A 4HB2B 4NSWA 4HAYB 2NMBA 1SGHA 2ROVA 5HE1A 2VRWB 3P7ZA 4KAXB 2LKOA 2UZSA 2D11A 2W2WA 2LOXA 4TKNA 1ZC4B 2IYBA 2K00A 5JHGA 3X23A 3MPXA 1FHWA 2EMTA 3KZ1A 3TVVA 5JP4A 2M38A 5KQ1A 1U29A 3WYFB 1J19A 3F5RA 2CRFA 4GN1A 4XWXA 1U2BA 3D8FA 4HAUB 5D3YA 3RCPA 2GS0A 2H7DA 3FSSA 2P8VA 2UZRA 3BJIA 5DH9B 3IVFA 1ZVRA 1V89A 2HTHB 2Z0QA 1TJ6A 2J0KA 2X18A 2YRYA 4MT7A 2DKPA 4GPTB 4DX8A 3DXDA 5L81A 1ZC3B 2AL6A 2I1KA 4A5KA 1P6SA 1Y5OA 4P7IA 1GG3A 4KHAA 1W1GA 1WJ1A 2DFKA 5D27A 1U5GA 4TYZA 2N0YA 4A6FB 3LJUX 5D3WA 1H10A 2Q13A 2G35A 1OQNA 2V76A 2COAA 3MDBC 5CLQB 5LOPB 4HB4B 1EVHA 2MKRA 3SNHA 1TXDA 3ZVRA 1DDVA 2RLOA 5GOWB 1AQCA 1FB8A 3KSYA 5C79A 2R0DA 1U27A 4MY6A 2RGNB 4HAVB 4EMOA 1KI1B 1X05A 1WVHA 4WJ7A 1X1FA 1BTNA 1X1GA 2YT1A 1QQGA 4MK0A 1U5DA 4KHBB 1ISNA 5KQ4A 2D4QA 2UVMA 1WGQA 1PMSA 2Y8GA 3FM8C 2MWNB 3PP2A 2ADZA 1U5EA 4CYEA 2LOZA 2ELAA 1WGUA 1FHXA 4DXAB 1MIZB 1OMWA 1DDWA 4HDOA 4HHVA 4A6FA 2Y7BA 4HAWB 1V5PA 1Y19B 3ULCA 1XCGA 2XQNM 2M14A 3T06A 4DX90 2D10A 3D8DA 4IAPA 3N7CA 1B55A 2LULA 2DN6A 1LW3A 2VSZA 4Y94A 1EAZA 3D8EA 2D9VA 2P0HA 2N23A 1UEFA 3CIKA 4KHOA 1WI1A 3BINA 4GMXB 1K5GB 4IFSA 2P0FA 2YS5A 3HQCA 4YONA 3ODXA 2QKMA 2KCJA 1TQZA 5CLLB 2PZ1A 4DBBA 1UNPA 4K2OA 5J3TA 3OANA 3PVLA 2RUKB 2COFA 1PFJA 2YF0A 2HE7A 2J0JA 2JP2A 3O96A 4PQ0A 1V61A 5D3XA 2FJLA 1IRSA 2DHJA 2KUPA 4HB3B 5HE3A 3VIAA 3NSUA 4CHMA 2DX5A 3CXBB 1KZGA 1V5UA 3KRXA 3SV1A 1UPRA 1GC7A 3ML4A 4EJNA 5D3VA 1X11A 2RNRB 1BAKA 3ULBA 1V88A 4CHJA 3A8PA 3A8QA 4A6HA 2P0DA 3FEHA 2YSZA 1NTYA 1ZSQA 1V5MA 2GCJA 2W2XC 5JHHA 2I5FA 1U5FA 2L2IA 5HE0A 5C16A 1FHOA 3GYOA 1MK7B 5DIFB 1MK9B 3V5WA 1NI2A 4Z2NA 2OTXA 1P3RA 1QC6A 2I5CA 4GMVA 1XD4A 5FI1A 1KZ7A 1Z87A 2J0MA 1Q67A 2DYQA 3U8ZA 4HAZB 4Z2MB 3TO1A 2CY5A 2R09A 1FOEA 5EFXA 2K2JA 2YS1A
chains in the Genus database with same CATH superfamily
2DHKA 4ZRKA 5C5BB 2ZPYA 2DKQA 3ODWA 3QWMA 4D6WA 2FJUB 4QJ4B 2NBVA 4WVFB 3PVWA 5M4YB 3P6AA 1W1DA 2J59M 1M7RA 3SUZA 2LYDA 3KY9A 1MKEA 1WJMA 2DX1A 4HDQA 4K17A 2BCJA 2Z0PA 1OY2A 2RSGA 3SO6A 1DBHA 2D9WA 5JLJB 2YT2A 2MFQA 1DDMA 4EKUA 2L1CA 3VOQA 2CY4A 2YT0A 5KCVA 5DHAB 1FAOA 2K49A 2YVCA 1SHCA 3PG7A 4GXBA 4HAXB 3UZTA 3DXEA 4C0AA 5DI9B 2CODA 3AU5A 3KRWA 3TCAA 3ZDTA 3NW8A 1W1HA 1BWNA 2D9YA 2IFSA 3HK0A 1XR0B 1J0WA 4KHBA 4HB0B 2D2QA 1K5DB 1XX0A 2ELBA 3HW2B 2MDXA 1E5WA 4F7UP 1FGZA 2Z59A 1MIXA 2DHIA 1XODA 4H8SA 2VKIA 5J3YA 1RJ2A 4HSIA 2KUQA 2LG1A 5C5BA 4GNKB 4NY0A 2I1JA 5J3QA 1BTKA 3F0WA 2D9ZA 3SYXA 1DROA 5LONB 3DXCA 4BBKA 1I2HA 2NZ8B 2YS3A 2DTCA 2DA0A 2GUMA 3QIJA 2COCA 2DLWA 2K2UA 1DYNA 4PNKA 1EF1A 3PZDA 1M7EA 1XKEA 2E2XA 1T77A 3PEGA 2EJ8A 2DYNA 4KVGB 1RRPB 1FGYA 1AWEA 3G9WA 1UNQA 4QJ5B 5DHFB 3PVUA 3AJ4A 4F7GA 4K2PA 3TW1A 4F7HA 3GYPA 4GZUA 1NU2A 1WG7A 4B6HA 2GJYA 2R2YA 2OQBA 3A98B 3M1IB 3TFMA 4ZRIA 3NWDA 1NTVA 5LG4B 2D9XA 1P5TA 1PLSA 2W2XD 4WSFA 3A58A 1UPQA 5FI0A 1UNRA 3AU4A 4L1RA 2Z0OA 4L6EA 3ODOA 3PSCA 3U7DA 2ROZB 4YL8A 4A6KA 2KGXB 2EC1A 2EMSA 2RVBB 3U12A 4D0NB 1H4RA 2GCLA 1EGXA 3QBVB 4K81A 5I2SA 2H7EA 1N3HA 1I7AA 2AEHA 1X86A 2CAYA 1MAIA 1MPHA 2QKLA 4IOYX 5C6RA 3DCXA 4HATB 1ZM0A 1LB1A 2KIEA 2Y8FA 3WA0A 4ZRJA 5HE2A 3FVCA 1GC6A 4HB2B 4NSWA 4HAYB 2NMBA 1SGHA 2ROVA 3B77A 5HE1A 2VRWB 3P7ZA 4KAXB 2LKOA 2UZSA 2D11A 2W2WA 2LOXA 4TKNA 1ZC4B 2IYBA 2K00A 5JHGA 3X23A 3MPXA 1FHWA 2EMTA 3KZ1A 3TVVA 5JP4A 2M38A 5KQ1A 1U29A 3WYFB 1J19A 3F5RA 2CRFA 4GN1A 4XWXA 1U2BA 3D8FA 4HAUB 5D3YA 3RCPA 2GS0A 2H7DA 3FSSA 2P8VA 2UZRA 3BJIA 5DH9B 3IVFA 1ZVRA 2Z13A 1V89A 5IRSA 2HTHB 2Z0QA 1TJ6A 2J0KA 2X18A 2YRYA 4MT7A 2DKPA 4GPTB 4DX8A 3DXDA 5L81A 1ZC3B 2AL6A 2I1KA 4A5KA 1P6SA 1Y5OA 4P7IA 1GG3A 4KHAA 1W1GA 1WJ1A 2DFKA 5D27A 1U5GA 4TYZA 2Z14A 2N0YA 4A6FB 3LJUX 3HIEA 5D3WA 1H10A 2Q13A 3HSAA 2G35A 1OQNA 2V76A 2COAA 3MDBC 4GOUA 5CLQB 5LOPB 4HB4B 1EVHA 2MKRA 3SNHA 1TXDA 3ZVRA 1DDVA 2RLOA 5GOWB 1AQCA 2K8EA 1FB8A 2RRFA 3KSYA 5C79A 2R0DA 1U27A 4MY6A 2RGNB 4HAVB 4EMOA 1KI1B 1X05A 1WVHA 4WJ7A 1X1FA 1BTNA 1X1GA 2YT1A 1QQGA 3NWFA 4MK0A 1U5DA 4KHBB 1ISNA 5KQ4A 2D4QA 2UVMA 1WGQA 1PMSA 2Y8GA 3FM8C 2MWNB 3PP2A 2ADZA 1U5EA 2ZKMX 4CYEA 2LOZA 2ELAA 1WGUA 4DIXA 1FHXA 4DXAB 1MIZB 1OMWA 1DDWA 4HDOA 4HHVA 4A6FA 2Y7BA 4HAWB 1V5PA 1Y19B 3ULCA 1XCGA 4OT1A 2XQNM 2M14A 2KR0A 3OHMB 3T06A 4DX90 4QXAB 2D10A 3D8DA 4IAPA 3N7CA 1B55A 2LULA 2DN6A 1LW3A 2VSZA 4Y94A 1EAZA 1MI1A 3D8EA 2D9VA 2KIGA 2P0HA 2N23A 5I2MA 1UEFA 3CIKA 4KHOA 1WI1A 3BINA 4GMXB 1K5GB 4IFSA 2P0FA 2YS5A 3HQCA 4YONA 4QJ3B 3ODXA 2QKMA 2KCJA 1TQZA 5CLLB 2PZ1A 4DBBA 3NWAA 1UNPA 4K2OA 5J3TA 3OANA 3PVLA 2RUKB 2COFA 1PFJA 2YF0A 2HE7A 2J0JA 2JP2A 3O96A 4PQ0A 1V61A 5D3XA 2FJLA 1IRSA 2DHJA 2KUPA 4HB3B 5HE3A 3VIAA 3NSUA 4CHMA 2DX5A 3CXBB 1KZGA 1V5UA 3KRXA 3SV1A 1UPRA 1ZYIA 1GC7A 3ML4A 4EJNA 5D3VA 1X11A 2RNRB 1BAKA 3ULBA 1V88A 4CHJA 3A8PA 3A8QA 4A6HA 2P0DA 3FEHA 2YSZA 1NTYA 1ZSQA 4OSNA 1V5MA 2GCJA 2W2XC 5JHHA 2I5FA 2Z4DA 1U5FA 2L2IA 5HE0A 5C16A 1FHOA 3GYOA 1MK7B 5DIFB 1MK9B 3V5WA 1NI2A 4Z2NA 2OTXA 1P3RA 1QC6A 2I5CA 4GMVA 1XD4A 5FI1A 1KZ7A 1Z87A 2J0MA 1Q67A 2DYQA 4CSQA 3U8ZA 4HAZB 4Z2MB 3TO1A 2CY5A 2R09A 1FOEA 5EFXA 2K2JA 2YS1A
chains in the Genus database with same CATH topology
2DHKA 4ZRKA 5C5BB 2ZPYA 2DKQA 3ODWA 3QWMA 4WVFB 3PVWA 3P6AA 1W1DA 2J59M 1M7RA 3SUZA 2LYDA 3KY9A 1MKEA 1WJMA 2DX1A 4HDQA 4K17A 2BCJA 2Z0PA 1OY2A 2RSGA 3SO6A 1DBHA 2D9WA 5JLJB 2MFQA 1DDMA 4EKUA 2L1CA 3VOQA 2CY4A 2YT0A 5KCVA 5DHAB 1FAOA 2YVCA 1SHCA 3PG7A 4GXBA 4HAXB 3UZTA 3DXEA 4C0AA 5DI9B 2CODA 3AU5A 3KRWA 3TCAA 3ZDTA 1W1HA 1BWNA 2D9YA 2IFSA 3HK0A 1XR0B 1J0WA 4HB0B 2D2QA 1K5DB 1XX0A 2ELBA 3HW2B 2MDXA 1E5WA 4F7UP 1FGZA 1MIXA 2DHIA 1XODA 4H8SA 2VKIA 5J3YA 1RJ2A 5C5BA 2LG1A 4NY0A 2I1JA 5J3QA 1BTKA 3F0WA 2D9ZA 3SYXA 1DROA 5LONB 3DXCA 4BBKA 1I2HA 2NZ8B 2YS3A 2DTCA 2DA0A 3QIJA 2COCA 2DLWA 2K2UA 1DYNA 4PNKA 1EF1A 3PZDA 1M7EA 1XKEA 2E2XA 3PEGA 2EJ8A 2DYNA 4KVGB 1RRPB 1FGYA 1AWEA 3G9WA 1UNQA 5DHFB 3PVUA 3AJ4A 4F7GA 4K2PA 3TW1A 4F7HA 3GYPA 4GZUA 1NU2A 1WG7A 4B6HA 2GJYA 2OQBA 3A98B 3M1IB 3TFMA 4ZRIA 1NTVA 2D9XA 1P5TA 1PLSA 2W2XD 4WSFA 1UPQA 5FI0A 1UNRA 3AU4A 2Z0OA 4L6EA 3ODOA 3PSCA 3U7DA 2ROZB 4YL8A 4A6KA 2KGXB 2EC1A 2EMSA 2RVBB 4D0NB 1H4RA 2GCLA 1EGXA 3QBVB 4K81A 2H7EA 1N3HA 1I7AA 2AEHA 1X86A 2CAYA 1MAIA 1MPHA 2QKLA 4IOYX 5C6RA 4HATB 1ZM0A 1LB1A 2Y8FA 3WA0A 4ZRJA 5HE2A 1GC6A 4HB2B 4NSWA 4HAYB 2NMBA 1SGHA 2ROVA 5HE1A 2VRWB 3P7ZA 4KAXB 2LKOA 2UZSA 2D11A 2W2WA 2LOXA 4TKNA 1ZC4B 2IYBA 2K00A 5JHGA 3X23A 3MPXA 1FHWA 2EMTA 3KZ1A 3TVVA 5JP4A 2M38A 5KQ1A 1U29A 3WYFB 1J19A 3F5RA 2CRFA 4GN1A 4XWXA 1U2BA 3D8FA 4HAUB 5D3YA 3RCPA 2GS0A 2H7DA 3FSSA 2P8VA 2UZRA 3BJIA 5DH9B 3IVFA 1ZVRA 1V89A 2HTHB 2Z0QA 1TJ6A 2J0KA 2X18A 2YRYA 4MT7A 2DKPA 4GPTB 4DX8A 3DXDA 5L81A 1ZC3B 2AL6A 2I1KA 4A5KA 1P6SA 1Y5OA 4P7IA 1GG3A 4KHAA 1W1GA 1WJ1A 2DFKA 5D27A 1U5GA 4TYZA 2N0YA 4A6FB 3LJUX 5D3WA 1H10A 2Q13A 2G35A 1OQNA 2V76A 2COAA 3MDBC 5CLQB 5LOPB 4HB4B 1EVHA 2MKRA 3SNHA 1TXDA 3ZVRA 1DDVA 2RLOA 5GOWB 1AQCA 1FB8A 3KSYA 5C79A 2R0DA 1U27A 4MY6A 2RGNB 4HAVB 4EMOA 1KI1B 1X05A 1WVHA 4WJ7A 1X1FA 1BTNA 1X1GA 2YT1A 1QQGA 4MK0A 1U5DA 4KHBB 1ISNA 5KQ4A 2D4QA 2UVMA 1WGQA 1PMSA 2Y8GA 3FM8C 2MWNB 3PP2A 2ADZA 1U5EA 4CYEA 2LOZA 2ELAA 1WGUA 1FHXA 4DXAB 1MIZB 1OMWA 1DDWA 4HDOA 4HHVA 4A6FA 2Y7BA 4HAWB 1V5PA 1Y19B 3ULCA 1XCGA 2XQNM 2M14A 3T06A 4DX90 2D10A 3D8DA 4IAPA 3N7CA 1B55A 2LULA 2DN6A 1LW3A 2VSZA 4Y94A 1EAZA 3D8EA 2D9VA 2P0HA 2N23A 1UEFA 3CIKA 4KHOA 1WI1A 3BINA 4GMXB 1K5GB 4IFSA 2P0FA 2YS5A 3HQCA 4YONA 3ODXA 2QKMA 2KCJA 1TQZA 5CLLB 2PZ1A 4DBBA 1UNPA 4K2OA 5J3TA 3OANA 3PVLA 2RUKB 2COFA 1PFJA 2YF0A 2HE7A 2J0JA 2JP2A 3O96A 4PQ0A 1V61A 5D3XA 2FJLA 1IRSA 2DHJA 2KUPA 4HB3B 5HE3A 3VIAA 3NSUA 4CHMA 2DX5A 3CXBB 1KZGA 1V5UA 3KRXA 3SV1A 1UPRA 1GC7A 3ML4A 4EJNA 5D3VA 1X11A 2RNRB 1BAKA 3ULBA 1V88A 4CHJA 3A8PA 3A8QA 4A6HA 2P0DA 3FEHA 2YSZA 1NTYA 1ZSQA 1V5MA 2GCJA 2W2XC 5JHHA 2I5FA 1U5FA 2L2IA 5HE0A 5C16A 1FHOA 3GYOA 1MK7B 5DIFB 1MK9B 3V5WA 1NI2A 4Z2NA 2OTXA 1P3RA 1QC6A 2I5CA 4GMVA 1XD4A 5FI1A 1KZ7A 1Z87A 2J0MA 1Q67A 2DYQA 3U8ZA 4HAZB 4Z2MB 3TO1A 2CY5A 2R09A 1FOEA 5EFXA 2K2JA 2YS1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DHK A;  4ZRK A;  5C5B B;  2ZPY A;  2DKQ A;  3ODW A;  3QWM A;  4WVF B;  3PVW A;  3P6A A;  1W1D A;  2J59 M;  1M7R A;  3SUZ A;  2LYD A;  3KY9 A;  1MKE A;  1WJM A;  2DX1 A;  4HDQ A;  4K17 A;  2BCJ A;  2Z0P A;  1OY2 A;  2RSG A;  3SO6 A;  1DBH A;  2D9W A;  5JLJ B;  2MFQ A;  1DDM A;  4EKU A;  2L1C A;  3VOQ A;  2CY4 A;  2YT0 A;  5KCV A;  5DHA B;  1FAO A;  2YVC A;  1SHC A;  3PG7 A;  4GXB A;  4HAX B;  3UZT A;  3DXE A;  4C0A A;  5DI9 B;  2COD A;  3AU5 A;  3KRW A;  3TCA A;  3ZDT A;  1W1H A;  1BWN A;  2D9Y A;  2IFS A;  3HK0 A;  1XR0 B;  1J0W A;  4HB0 B;  2D2Q A;  1K5D B;  1XX0 A;  2ELB A;  3HW2 B;  2MDX A;  1E5W A;  4F7U P;  1FGZ A;  1MIX A;  2DHI A;  1XOD A;  4H8S A;  2VKI A;  5J3Y A;  1RJ2 A;  5C5B A;  2LG1 A;  4NY0 A;  2I1J A;  5J3Q A;  1BTK A;  3F0W A;  2D9Z A;  3SYX A;  1DRO A;  5LON B;  3DXC A;  4BBK A;  1I2H A;  2NZ8 B;  2YS3 A;  2DTC A;  2DA0 A;  3QIJ A;  2COC A;  2DLW A;  2K2U A;  1DYN A;  4PNK A;  1EF1 A;  3PZD A;  1M7E A;  1XKE A;  2E2X A;  3PEG A;  2EJ8 A;  2DYN A;  4KVG B;  1RRP B;  1FGY A;  1AWE A;  3G9W A;  1UNQ A;  5DHF B;  3PVU A;  3AJ4 A;  4F7G A;  4K2P A;  3TW1 A;  4F7H A;  3GYP A;  4GZU A;  1NU2 A;  1WG7 A;  4B6H A;  2GJY A;  2OQB A;  3A98 B;  3M1I B;  3TFM A;  4ZRI A;  1NTV A;  2D9X A;  1P5T A;  1PLS A;  2W2X D;  4WSF A;  1UPQ A;  5FI0 A;  1UNR A;  3AU4 A;  2Z0O A;  4L6E A;  3ODO A;  3PSC A;  3U7D A;  2ROZ B;  4YL8 A;  4A6K A;  2KGX B;  2EC1 A;  2EMS A;  2RVB B;  4D0N B;  1H4R A;  2GCL A;  1EGX A;  3QBV B;  4K81 A;  2H7E A;  1N3H A;  1I7A A;  2AEH A;  1X86 A;  2CAY A;  1MAI A;  1MPH A;  2QKL A;  4IOY X;  5C6R A;  4HAT B;  1ZM0 A;  1LB1 A;  2Y8F A;  3WA0 A;  4ZRJ A;  5HE2 A;  1GC6 A;  4HB2 B;  4NSW A;  4HAY B;  2NMB A;  1SGH A;  2ROV A;  5HE1 A;  2VRW B;  3P7Z A;  4KAX B;  2LKO A;  2UZS A;  2D11 A;  2W2W A;  2LOX A;  4TKN A;  1ZC4 B;  2IYB A;  2K00 A;  5JHG A;  3X23 A;  3MPX A;  1FHW A;  2EMT A;  3KZ1 A;  3TVV A;  5JP4 A;  2M38 A;  5KQ1 A;  1U29 A;  3WYF B;  1J19 A;  3F5R A;  2CRF A;  4GN1 A;  4XWX A;  1U2B A;  3D8F A;  4HAU B;  5D3Y A;  3RCP A;  2GS0 A;  2H7D A;  3FSS A;  2P8V A;  2UZR A;  3BJI A;  5DH9 B;  3IVF A;  1ZVR A;  1V89 A;  2HTH B;  2Z0Q A;  1TJ6 A;  2J0K A;  2X18 A;  2YRY A;  4MT7 A;  2DKP A;  4GPT B;  4DX8 A;  3DXD A;  5L81 A;  1ZC3 B;  2AL6 A;  2I1K A;  4A5K A;  1P6S A;  1Y5O A;  4P7I A;  1GG3 A;  4KHA A;  1W1G A;  1WJ1 A;  2DFK A;  5D27 A;  1U5G A;  4TYZ A;  2N0Y A;  4A6F B;  3LJU X;  5D3W A;  1H10 A;  2Q13 A;  2G35 A;  1OQN A;  2V76 A;  2COA A;  3MDB C;  5CLQ B;  5LOP B;  4HB4 B;  1EVH A;  2MKR A;  3SNH A;  1TXD A;  3ZVR A;  1DDV A;  2RLO A;  5GOW B;  1AQC A;  1FB8 A;  3KSY A;  5C79 A;  2R0D A;  1U27 A;  4MY6 A;  2RGN B;  4HAV B;  4EMO A;  1KI1 B;  1X05 A;  1WVH A;  4WJ7 A;  1X1F A;  1BTN A;  1X1G A;  2YT1 A;  1QQG A;  4MK0 A;  1U5D A;  4KHB B;  1ISN A;  5KQ4 A;  2D4Q A;  2UVM A;  1WGQ A;  1PMS A;  2Y8G A;  3FM8 C;  2MWN B;  3PP2 A;  2ADZ A;  1U5E A;  4CYE A;  2LOZ A;  2ELA A;  1WGU A;  1FHX A;  4DXA B;  1MIZ B;  1OMW A;  1DDW A;  4HDO A;  4HHV A;  4A6F A;  2Y7B A;  4HAW B;  1V5P A;  1Y19 B;  3ULC A;  1XCG A;  2XQN M;  2M14 A;  3T06 A;  4DX9 0;  2D10 A;  3D8D A;  4IAP A;  3N7C A;  1B55 A;  2LUL A;  2DN6 A;  1LW3 A;  2VSZ A;  4Y94 A;  1EAZ A;  3D8E A;  2D9V A;  2P0H A;  2N23 A;  1UEF A;  3CIK A;  4KHO A;  1WI1 A;  3BIN A;  4GMX B;  1K5G B;  4IFS A;  2P0F A;  2YS5 A;  3HQC A;  4YON A;  3ODX A;  2QKM A;  2KCJ A;  1TQZ A;  5CLL B;  2PZ1 A;  4DBB A;  1UNP A;  4K2O A;  5J3T A;  3OAN A;  3PVL A;  2RUK B;  2COF A;  1PFJ A;  2YF0 A;  2HE7 A;  2J0J A;  2JP2 A;  3O96 A;  4PQ0 A;  1V61 A;  5D3X A;  2FJL A;  1IRS A;  2DHJ A;  2KUP A;  4HB3 B;  5HE3 A;  3VIA A;  3NSU A;  4CHM A;  2DX5 A;  3CXB B;  1KZG A;  1V5U A;  3KRX A;  3SV1 A;  1UPR A;  1GC7 A;  3ML4 A;  4EJN A;  5D3V A;  1X11 A;  2RNR B;  1BAK A;  3ULB A;  1V88 A;  4CHJ A;  3A8P A;  3A8Q A;  4A6H A;  2P0D A;  3FEH A;  2YSZ A;  1NTY A;  1ZSQ A;  1V5M A;  2GCJ A;  2W2X C;  5JHH A;  2I5F A;  1U5F A;  2L2I A;  5HE0 A;  5C16 A;  1FHO A;  3GYO A;  1MK7 B;  5DIF B;  1MK9 B;  3V5W A;  1NI2 A;  4Z2N A;  2OTX A;  1P3R A;  1QC6 A;  2I5C A;  4GMV A;  1XD4 A;  5FI1 A;  1KZ7 A;  1Z87 A;  2J0M A;  1Q67 A;  2DYQ A;  3U8Z A;  4HAZ B;  4Z2M B;  3TO1 A;  2CY5 A;  2R09 A;  1FOE A;  5EFX A;  2K2J A;  2YS1 A; 
#chains in the Genus database with same CATH topology
 2DHK A;  4ZRK A;  5C5B B;  2ZPY A;  2DKQ A;  3ODW A;  3QWM A;  4D6W A;  2FJU B;  4QJ4 B;  2NBV A;  4WVF B;  3PVW A;  5M4Y B;  3P6A A;  1W1D A;  2J59 M;  1M7R A;  3SUZ A;  2LYD A;  3KY9 A;  1MKE A;  1WJM A;  2DX1 A;  4HDQ A;  4K17 A;  2BCJ A;  2Z0P A;  1OY2 A;  2RSG A;  3SO6 A;  1DBH A;  2D9W A;  5JLJ B;  2YT2 A;  2MFQ A;  1DDM A;  4EKU A;  2L1C A;  3VOQ A;  2CY4 A;  2YT0 A;  5KCV A;  5DHA B;  1FAO A;  2K49 A;  2YVC A;  1SHC A;  3PG7 A;  4GXB A;  4HAX B;  3UZT A;  3DXE A;  4C0A A;  5DI9 B;  2COD A;  3AU5 A;  3KRW A;  3TCA A;  3ZDT A;  3NW8 A;  1W1H A;  1BWN A;  2D9Y A;  2IFS A;  3HK0 A;  1XR0 B;  1J0W A;  4KHB A;  4HB0 B;  2D2Q A;  1K5D B;  1XX0 A;  2ELB A;  3HW2 B;  2MDX A;  1E5W A;  4F7U P;  1FGZ A;  2Z59 A;  1MIX A;  2DHI A;  1XOD A;  4H8S A;  2VKI A;  5J3Y A;  1RJ2 A;  4HSI A;  2KUQ A;  2LG1 A;  5C5B A;  4GNK B;  4NY0 A;  2I1J A;  5J3Q A;  1BTK A;  3F0W A;  2D9Z A;  3SYX A;  1DRO A;  5LON B;  3DXC A;  4BBK A;  1I2H A;  2NZ8 B;  2YS3 A;  2DTC A;  2DA0 A;  2GUM A;  3QIJ A;  2COC A;  2DLW A;  2K2U A;  1DYN A;  4PNK A;  1EF1 A;  3PZD A;  1M7E A;  1XKE A;  2E2X A;  1T77 A;  3PEG A;  2EJ8 A;  2DYN A;  4KVG B;  1RRP B;  1FGY A;  1AWE A;  3G9W A;  1UNQ A;  4QJ5 B;  5DHF B;  3PVU A;  3AJ4 A;  4F7G A;  4K2P A;  3TW1 A;  4F7H A;  3GYP A;  4GZU A;  1NU2 A;  1WG7 A;  4B6H A;  2GJY A;  2R2Y A;  2OQB A;  3A98 B;  3M1I B;  3TFM A;  4ZRI A;  3NWD A;  1NTV A;  5LG4 B;  2D9X A;  1P5T A;  1PLS A;  2W2X D;  4WSF A;  3A58 A;  1UPQ A;  5FI0 A;  1UNR A;  3AU4 A;  4L1R A;  2Z0O A;  4L6E A;  3ODO A;  3PSC A;  3U7D A;  2ROZ B;  4YL8 A;  4A6K A;  2KGX B;  2EC1 A;  2EMS A;  2RVB B;  3U12 A;  4D0N B;  1H4R A;  2GCL A;  1EGX A;  3QBV B;  4K81 A;  5I2S A;  2H7E A;  1N3H A;  1I7A A;  2AEH A;  1X86 A;  2CAY A;  1MAI A;  1MPH A;  2QKL A;  4IOY X;  5C6R A;  3DCX A;  4HAT B;  1ZM0 A;  1LB1 A;  2KIE A;  2Y8F A;  3WA0 A;  4ZRJ A;  5HE2 A;  3FVC A;  1GC6 A;  4HB2 B;  4NSW A;  4HAY B;  2NMB A;  1SGH A;  2ROV A;  3B77 A;  5HE1 A;  2VRW B;  3P7Z A;  4KAX B;  2LKO A;  2UZS A;  2D11 A;  2W2W A;  2LOX A;  4TKN A;  1ZC4 B;  2IYB A;  2K00 A;  5JHG A;  3X23 A;  3MPX A;  1FHW A;  2EMT A;  3KZ1 A;  3TVV A;  5JP4 A;  2M38 A;  5KQ1 A;  1U29 A;  3WYF B;  1J19 A;  3F5R A;  2CRF A;  4GN1 A;  4XWX A;  1U2B A;  3D8F A;  4HAU B;  5D3Y A;  3RCP A;  2GS0 A;  2H7D A;  3FSS A;  2P8V A;  2UZR A;  3BJI A;  5DH9 B;  3IVF A;  1ZVR A;  2Z13 A;  1V89 A;  5IRS A;  2HTH B;  2Z0Q A;  1TJ6 A;  2J0K A;  2X18 A;  2YRY A;  4MT7 A;  2DKP A;  4GPT B;  4DX8 A;  3DXD A;  5L81 A;  1ZC3 B;  2AL6 A;  2I1K A;  4A5K A;  1P6S A;  1Y5O A;  4P7I A;  1GG3 A;  4KHA A;  1W1G A;  1WJ1 A;  2DFK A;  5D27 A;  1U5G A;  4TYZ A;  2Z14 A;  2N0Y A;  4A6F B;  3LJU X;  3HIE A;  5D3W A;  1H10 A;  2Q13 A;  3HSA A;  2G35 A;  1OQN A;  2V76 A;  2COA A;  3MDB C;  4GOU A;  5CLQ B;  5LOP B;  4HB4 B;  1EVH A;  2MKR A;  3SNH A;  1TXD A;  3ZVR A;  1DDV A;  2RLO A;  5GOW B;  1AQC A;  2K8E A;  1FB8 A;  2RRF A;  3KSY A;  5C79 A;  2R0D A;  1U27 A;  4MY6 A;  2RGN B;  4HAV B;  4EMO A;  1KI1 B;  1X05 A;  1WVH A;  4WJ7 A;  1X1F A;  1BTN A;  1X1G A;  2YT1 A;  1QQG A;  3NWF A;  4MK0 A;  1U5D A;  4KHB B;  1ISN A;  5KQ4 A;  2D4Q A;  2UVM A;  1WGQ A;  1PMS A;  2Y8G A;  3FM8 C;  2MWN B;  3PP2 A;  2ADZ A;  1U5E A;  2ZKM X;  4CYE A;  2LOZ A;  2ELA A;  1WGU A;  4DIX A;  1FHX A;  4DXA B;  1MIZ B;  1OMW A;  1DDW A;  4HDO A;  4HHV A;  4A6F A;  2Y7B A;  4HAW B;  1V5P A;  1Y19 B;  3ULC A;  1XCG A;  4OT1 A;  2XQN M;  2M14 A;  2KR0 A;  3OHM B;  3T06 A;  4DX9 0;  4QXA B;  2D10 A;  3D8D A;  4IAP A;  3N7C A;  1B55 A;  2LUL A;  2DN6 A;  1LW3 A;  2VSZ A;  4Y94 A;  1EAZ A;  1MI1 A;  3D8E A;  2D9V A;  2KIG A;  2P0H A;  2N23 A;  5I2M A;  1UEF A;  3CIK A;  4KHO A;  1WI1 A;  3BIN A;  4GMX B;  1K5G B;  4IFS A;  2P0F A;  2YS5 A;  3HQC A;  4YON A;  4QJ3 B;  3ODX A;  2QKM A;  2KCJ A;  1TQZ A;  5CLL B;  2PZ1 A;  4DBB A;  3NWA A;  1UNP A;  4K2O A;  5J3T A;  3OAN A;  3PVL A;  2RUK B;  2COF A;  1PFJ A;  2YF0 A;  2HE7 A;  2J0J A;  2JP2 A;  3O96 A;  4PQ0 A;  1V61 A;  5D3X A;  2FJL A;  1IRS A;  2DHJ A;  2KUP A;  4HB3 B;  5HE3 A;  3VIA A;  3NSU A;  4CHM A;  2DX5 A;  3CXB B;  1KZG A;  1V5U A;  3KRX A;  3SV1 A;  1UPR A;  1ZYI A;  1GC7 A;  3ML4 A;  4EJN A;  5D3V A;  1X11 A;  2RNR B;  1BAK A;  3ULB A;  1V88 A;  4CHJ A;  3A8P A;  3A8Q A;  4A6H A;  2P0D A;  3FEH A;  2YSZ A;  1NTY A;  1ZSQ A;  4OSN A;  1V5M A;  2GCJ A;  2W2X C;  5JHH A;  2I5F A;  2Z4D A;  1U5F A;  2L2I A;  5HE0 A;  5C16 A;  1FHO A;  3GYO A;  1MK7 B;  5DIF B;  1MK9 B;  3V5W A;  1NI2 A;  4Z2N A;  2OTX A;  1P3R A;  1QC6 A;  2I5C A;  4GMV A;  1XD4 A;  5FI1 A;  1KZ7 A;  1Z87 A;  2J0M A;  1Q67 A;  2DYQ A;  4CSQ A;  3U8Z A;  4HAZ B;  4Z2M B;  3TO1 A;  2CY5 A;  2R09 A;  1FOE A;  5EFX A;  2K2J A;  2YS1 A; 
#chains in the Genus database with same CATH homology
 2DHK A;  4ZRK A;  5C5B B;  2ZPY A;  2DKQ A;  3ODW A;  3QWM A;  4WVF B;  3PVW A;  3P6A A;  1W1D A;  2J59 M;  1M7R A;  3SUZ A;  2LYD A;  3KY9 A;  1MKE A;  1WJM A;  2DX1 A;  4HDQ A;  4K17 A;  2BCJ A;  2Z0P A;  1OY2 A;  2RSG A;  3SO6 A;  1DBH A;  2D9W A;  5JLJ B;  2MFQ A;  1DDM A;  4EKU A;  2L1C A;  3VOQ A;  2CY4 A;  2YT0 A;  5KCV A;  5DHA B;  1FAO A;  2YVC A;  1SHC A;  3PG7 A;  4GXB A;  4HAX B;  3UZT A;  3DXE A;  4C0A A;  5DI9 B;  2COD A;  3AU5 A;  3KRW A;  3TCA A;  3ZDT A;  1W1H A;  1BWN A;  2D9Y A;  2IFS A;  3HK0 A;  1XR0 B;  1J0W A;  4HB0 B;  2D2Q A;  1K5D B;  1XX0 A;  2ELB A;  3HW2 B;  2MDX A;  1E5W A;  4F7U P;  1FGZ A;  1MIX A;  2DHI A;  1XOD A;  4H8S A;  2VKI A;  5J3Y A;  1RJ2 A;  5C5B A;  2LG1 A;  4NY0 A;  2I1J A;  5J3Q A;  1BTK A;  3F0W A;  2D9Z A;  3SYX A;  1DRO A;  5LON B;  3DXC A;  4BBK A;  1I2H A;  2NZ8 B;  2YS3 A;  2DTC A;  2DA0 A;  3QIJ A;  2COC A;  2DLW A;  2K2U A;  1DYN A;  4PNK A;  1EF1 A;  3PZD A;  1M7E A;  1XKE A;  2E2X A;  3PEG A;  2EJ8 A;  2DYN A;  4KVG B;  1RRP B;  1FGY A;  1AWE A;  3G9W A;  1UNQ A;  5DHF B;  3PVU A;  3AJ4 A;  4F7G A;  4K2P A;  3TW1 A;  4F7H A;  3GYP A;  4GZU A;  1NU2 A;  1WG7 A;  4B6H A;  2GJY A;  2OQB A;  3A98 B;  3M1I B;  3TFM A;  4ZRI A;  1NTV A;  2D9X A;  1P5T A;  1PLS A;  2W2X D;  4WSF A;  1UPQ A;  5FI0 A;  1UNR A;  3AU4 A;  2Z0O A;  4L6E A;  3ODO A;  3PSC A;  3U7D A;  2ROZ B;  4YL8 A;  4A6K A;  2KGX B;  2EC1 A;  2EMS A;  2RVB B;  4D0N B;  1H4R A;  2GCL A;  1EGX A;  3QBV B;  4K81 A;  2H7E A;  1N3H A;  1I7A A;  2AEH A;  1X86 A;  2CAY A;  1MAI A;  1MPH A;  2QKL A;  4IOY X;  5C6R A;  4HAT B;  1ZM0 A;  1LB1 A;  2Y8F A;  3WA0 A;  4ZRJ A;  5HE2 A;  1GC6 A;  4HB2 B;  4NSW A;  4HAY B;  2NMB A;  1SGH A;  2ROV A;  5HE1 A;  2VRW B;  3P7Z A;  4KAX B;  2LKO A;  2UZS A;  2D11 A;  2W2W A;  2LOX A;  4TKN A;  1ZC4 B;  2IYB A;  2K00 A;  5JHG A;  3X23 A;  3MPX A;  1FHW A;  2EMT A;  3KZ1 A;  3TVV A;  5JP4 A;  2M38 A;  5KQ1 A;  1U29 A;  3WYF B;  1J19 A;  3F5R A;  2CRF A;  4GN1 A;  4XWX A;  1U2B A;  3D8F A;  4HAU B;  5D3Y A;  3RCP A;  2GS0 A;  2H7D A;  3FSS A;  2P8V A;  2UZR A;  3BJI A;  5DH9 B;  3IVF A;  1ZVR A;  1V89 A;  2HTH B;  2Z0Q A;  1TJ6 A;  2J0K A;  2X18 A;  2YRY A;  4MT7 A;  2DKP A;  4GPT B;  4DX8 A;  3DXD A;  5L81 A;  1ZC3 B;  2AL6 A;  2I1K A;  4A5K A;  1P6S A;  1Y5O A;  4P7I A;  1GG3 A;  4KHA A;  1W1G A;  1WJ1 A;  2DFK A;  5D27 A;  1U5G A;  4TYZ A;  2N0Y A;  4A6F B;  3LJU X;  5D3W A;  1H10 A;  2Q13 A;  2G35 A;  1OQN A;  2V76 A;  2COA A;  3MDB C;  5CLQ B;  5LOP B;  4HB4 B;  1EVH A;  2MKR A;  3SNH A;  1TXD A;  3ZVR A;  1DDV A;  2RLO A;  5GOW B;  1AQC A;  1FB8 A;  3KSY A;  5C79 A;  2R0D A;  1U27 A;  4MY6 A;  2RGN B;  4HAV B;  4EMO A;  1KI1 B;  1X05 A;  1WVH A;  4WJ7 A;  1X1F A;  1BTN A;  1X1G A;  2YT1 A;  1QQG A;  4MK0 A;  1U5D A;  4KHB B;  1ISN A;  5KQ4 A;  2D4Q A;  2UVM A;  1WGQ A;  1PMS A;  2Y8G A;  3FM8 C;  2MWN B;  3PP2 A;  2ADZ A;  1U5E A;  4CYE A;  2LOZ A;  2ELA A;  1WGU A;  1FHX A;  4DXA B;  1MIZ B;  1OMW A;  1DDW A;  4HDO A;  4HHV A;  4A6F A;  2Y7B A;  4HAW B;  1V5P A;  1Y19 B;  3ULC A;  1XCG A;  2XQN M;  2M14 A;  3T06 A;  4DX9 0;  2D10 A;  3D8D A;  4IAP A;  3N7C A;  1B55 A;  2LUL A;  2DN6 A;  1LW3 A;  2VSZ A;  4Y94 A;  1EAZ A;  3D8E A;  2D9V A;  2P0H A;  2N23 A;  1UEF A;  3CIK A;  4KHO A;  1WI1 A;  3BIN A;  4GMX B;  1K5G B;  4IFS A;  2P0F A;  2YS5 A;  3HQC A;  4YON A;  3ODX A;  2QKM A;  2KCJ A;  1TQZ A;  5CLL B;  2PZ1 A;  4DBB A;  1UNP A;  4K2O A;  5J3T A;  3OAN A;  3PVL A;  2RUK B;  2COF A;  1PFJ A;  2YF0 A;  2HE7 A;  2J0J A;  2JP2 A;  3O96 A;  4PQ0 A;  1V61 A;  5D3X A;  2FJL A;  1IRS A;  2DHJ A;  2KUP A;  4HB3 B;  5HE3 A;  3VIA A;  3NSU A;  4CHM A;  2DX5 A;  3CXB B;  1KZG A;  1V5U A;  3KRX A;  3SV1 A;  1UPR A;  1GC7 A;  3ML4 A;  4EJN A;  5D3V A;  1X11 A;  2RNR B;  1BAK A;  3ULB A;  1V88 A;  4CHJ A;  3A8P A;  3A8Q A;  4A6H A;  2P0D A;  3FEH A;  2YSZ A;  1NTY A;  1ZSQ A;  1V5M A;  2GCJ A;  2W2X C;  5JHH A;  2I5F A;  1U5F A;  2L2I A;  5HE0 A;  5C16 A;  1FHO A;  3GYO A;  1MK7 B;  5DIF B;  1MK9 B;  3V5W A;  1NI2 A;  4Z2N A;  2OTX A;  1P3R A;  1QC6 A;  2I5C A;  4GMV A;  1XD4 A;  5FI1 A;  1KZ7 A;  1Z87 A;  2J0M A;  1Q67 A;  2DYQ A;  3U8Z A;  4HAZ B;  4Z2M B;  3TO1 A;  2CY5 A;  2R09 A;  1FOE A;  5EFX A;  2K2J A;  2YS1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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