2HIIC

Heterotrimeric pcna sliding clamp
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
243
structure length
243
Chain Sequence
MKVVYDDVRVLKDIIQALARLVDEAVLKFKQDSVELVALDRAHISLISVNLPREMFKEYDVNDEFKFGFNTQYLMKILKVAKRKEAIEIASESPDSVIINIIGSTNREFNVRNLEVSEQEIPEINLQFDISATISSDGFKSAISEVSTVTDNVVVEGHEDRILIKAEGESEVEVEFSKDTGGLQDLEFSKESKNSYSAEYLDDVLSLTKLSDYVKISFGNQKPLQLFFNMEGGGKVTYLLAPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
pubmed doi rcsb
molecule tags Replication
source organism Sulfolobus solfataricus
molecule keywords PCNA1 (SSO0397)
total genus 61
structure length 243
sequence length 243
chains with identical sequence Z
ec nomenclature
pdb deposition date 2006-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
C PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2hiiC00
2NTIC 3AIZC 1SXJF 5JNED 5B7OA 4RJFA 5A6DA 3HI8A 5HACA 3VKXA 2ZVWA 1CZDA 4ZTDA 2IX2A 2IJXA 1UL1A 2HIKB 3GPNA 2IX2B 3V60B 2IO4A 3GGRA 1VYMA 3V62B 2IO4B 2HIKC 3GGRB 2HIIA 3P83A 3AIXA 1U76A 2AWAA 1U7BA 4TR6A 1B77A 2IZOB 3A1JA 1IZ4A 2HIIB 3FDSC 2ZVLA 3G65A 4D2GA 3GGRC 1PLQA 3A1JB 1AXCA 2Z0LA 5IY4A 5IXAA 2IZOC 1B8HA 2HIIC 1RWZA 3FDSD 3IFVA 2IX2C 3TBLA 3I2MX 5H0TA 2NTIA 3AIZA 5DAIA 3A2FB 3U5ZF 4HK1A 3AIXB 1RXMA 1PLRA 2OD8A 3P87A 2ZVKA 3G65B 1GE8A 4L6PA 3LX1A 1ISQA 2ZVVA 5E0UA 2AVTA 5AUJA 3A1JC 3WGWA 1VYJA 5E0TA 3U61F 2HIKA 3G65C 3GPMA 5CFKA 3P91A 1W60A 4YHRA 3LX2A 4CS5A 1RXZA 5DA7A 3HSLX 2ZVMA 3V61B 5E0VA 2NTIB 4L60A 5IWDA 1DMLA 3F1WA 1YYPA 3U60F 1IZ5A 1UD9A 3K4XA 1T6LA
chains in the Genus database with same CATH superfamily
2NTIC 3AIZC 1SXJF 5JNED 5B7OA 4RJFA 5A6DA 3HI8A 5HACA 3VKXA 2ZVWA 1CZDA 4ZTDA 2IX2A 2IJXA 1UL1A 2HIKB 3GPNA 2IX2B 3V60B 2IO4A 3GGRA 1VYMA 3V62B 2IO4B 2HIKC 3GGRB 2HIIA 3P83A 3AIXA 1U76A 2AWAA 1U7BA 4TR6A 1B77A 2IZOB 3A1JA 1IZ4A 2HIIB 3FDSC 2ZVLA 3G65A 4D2GA 3GGRC 1PLQA 3A1JB 1AXCA 2Z0LA 5IY4A 5IXAA 2IZOC 1B8HA 2HIIC 1RWZA 3FDSD 3IFVA 2IX2C 3TBLA 3I2MX 5H0TA 2NTIA 3AIZA 5DAIA 3A2FB 3U5ZF 4HK1A 3AIXB 1RXMA 1PLRA 2OD8A 3P87A 2ZVKA 3G65B 1GE8A 4L6PA 3LX1A 1ISQA 2ZVVA 5E0UA 2AVTA 5AUJA 3A1JC 3WGWA 1VYJA 5E0TA 3U61F 2HIKA 3G65C 3GPMA 5CFKA 3P91A 1W60A 4YHRA 3LX2A 4CS5A 1RXZA 5DA7A 3HSLX 2ZVMA 3V61B 5E0VA 2NTIB 4L60A 5IWDA 1DMLA 3F1WA 1YYPA 3U60F 1IZ5A 1UD9A 3K4XA 1T6LA
chains in the Genus database with same CATH topology
2NTIC 3AIZC 1SXJF 5JNED 5B7OA 4RJFA 5A6DA 3HI8A 5HACA 3VKXA 2ZVWA 1CZDA 4ZTDA 2IX2A 2IJXA 1UL1A 2HIKB 3GPNA 2IX2B 3V60B 2IO4A 3GGRA 1VYMA 3V62B 2IO4B 2HIKC 3GGRB 2HIIA 3P83A 3AIXA 1U76A 2AWAA 1U7BA 4TR6A 1B77A 2IZOB 3A1JA 1IZ4A 2HIIB 3FDSC 2ZVLA 3G65A 4D2GA 3GGRC 1PLQA 3A1JB 1AXCA 2Z0LA 5IY4A 5IXAA 2IZOC 1B8HA 2HIIC 1RWZA 3FDSD 3IFVA 2IX2C 3TBLA 3I2MX 5H0TA 2NTIA 3AIZA 5DAIA 3A2FB 3U5ZF 4HK1A 3AIXB 1RXMA 1PLRA 2OD8A 3P87A 2ZVKA 3G65B 1GE8A 4L6PA 3LX1A 1ISQA 2ZVVA 5E0UA 2AVTA 5AUJA 3A1JC 3WGWA 1VYJA 5E0TA 3U61F 2HIKA 3G65C 3GPMA 5CFKA 3P91A 1W60A 4YHRA 3LX2A 4CS5A 1RXZA 5DA7A 3HSLX 2ZVMA 3V61B 5E0VA 2NTIB 4L60A 5IWDA 1DMLA 3F1WA 1YYPA 3U60F 1IZ5A 1UD9A 3K4XA 1T6LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NTI C;  3AIZ C;  1SXJ F;  5JNE D;  5B7O A;  4RJF A;  5A6D A;  3HI8 A;  5HAC A;  3VKX A;  2ZVW A;  1CZD A;  4ZTD A;  2IX2 A;  2IJX A;  1UL1 A;  2HIK B;  3GPN A;  2IX2 B;  3V60 B;  2IO4 A;  3GGR A;  1VYM A;  3V62 B;  2IO4 B;  2HIK C;  3GGR B;  2HII A;  3P83 A;  3AIX A;  1U76 A;  2AWA A;  1U7B A;  4TR6 A;  1B77 A;  2IZO B;  3A1J A;  1IZ4 A;  2HII B;  3FDS C;  2ZVL A;  3G65 A;  4D2G A;  3GGR C;  1PLQ A;  3A1J B;  1AXC A;  2Z0L A;  5IY4 A;  5IXA A;  2IZO C;  1B8H A;  2HII C;  1RWZ A;  3FDS D;  3IFV A;  2IX2 C;  3TBL A;  3I2M X;  5H0T A;  2NTI A;  3AIZ A;  5DAI A;  3A2F B;  3U5Z F;  4HK1 A;  3AIX B;  1RXM A;  1PLR A;  2OD8 A;  3P87 A;  2ZVK A;  3G65 B;  1GE8 A;  4L6P A;  3LX1 A;  1ISQ A;  2ZVV A;  5E0U A;  2AVT A;  5AUJ A;  3A1J C;  3WGW A;  1VYJ A;  5E0T A;  3U61 F;  2HIK A;  3G65 C;  3GPM A;  5CFK A;  3P91 A;  1W60 A;  4YHR A;  3LX2 A;  4CS5 A;  1RXZ A;  5DA7 A;  3HSL X;  2ZVM A;  3V61 B;  5E0V A;  2NTI B;  4L60 A;  5IWD A;  1DML A;  3F1W A;  1YYP A;  3U60 F;  1IZ5 A;  1UD9 A;  3K4X A;  1T6L A; 
#chains in the Genus database with same CATH topology
 2NTI C;  3AIZ C;  1SXJ F;  5JNE D;  5B7O A;  4RJF A;  5A6D A;  3HI8 A;  5HAC A;  3VKX A;  2ZVW A;  1CZD A;  4ZTD A;  2IX2 A;  2IJX A;  1UL1 A;  2HIK B;  3GPN A;  2IX2 B;  3V60 B;  2IO4 A;  3GGR A;  1VYM A;  3V62 B;  2IO4 B;  2HIK C;  3GGR B;  2HII A;  3P83 A;  3AIX A;  1U76 A;  2AWA A;  1U7B A;  4TR6 A;  1B77 A;  2IZO B;  3A1J A;  1IZ4 A;  2HII B;  3FDS C;  2ZVL A;  3G65 A;  4D2G A;  3GGR C;  1PLQ A;  3A1J B;  1AXC A;  2Z0L A;  5IY4 A;  5IXA A;  2IZO C;  1B8H A;  2HII C;  1RWZ A;  3FDS D;  3IFV A;  2IX2 C;  3TBL A;  3I2M X;  5H0T A;  2NTI A;  3AIZ A;  5DAI A;  3A2F B;  3U5Z F;  4HK1 A;  3AIX B;  1RXM A;  1PLR A;  2OD8 A;  3P87 A;  2ZVK A;  3G65 B;  1GE8 A;  4L6P A;  3LX1 A;  1ISQ A;  2ZVV A;  5E0U A;  2AVT A;  5AUJ A;  3A1J C;  3WGW A;  1VYJ A;  5E0T A;  3U61 F;  2HIK A;  3G65 C;  3GPM A;  5CFK A;  3P91 A;  1W60 A;  4YHR A;  3LX2 A;  4CS5 A;  1RXZ A;  5DA7 A;  3HSL X;  2ZVM A;  3V61 B;  5E0V A;  2NTI B;  4L60 A;  5IWD A;  1DML A;  3F1W A;  1YYP A;  3U60 F;  1IZ5 A;  1UD9 A;  3K4X A;  1T6L A; 
#chains in the Genus database with same CATH homology
 2NTI C;  3AIZ C;  1SXJ F;  5JNE D;  5B7O A;  4RJF A;  5A6D A;  3HI8 A;  5HAC A;  3VKX A;  2ZVW A;  1CZD A;  4ZTD A;  2IX2 A;  2IJX A;  1UL1 A;  2HIK B;  3GPN A;  2IX2 B;  3V60 B;  2IO4 A;  3GGR A;  1VYM A;  3V62 B;  2IO4 B;  2HIK C;  3GGR B;  2HII A;  3P83 A;  3AIX A;  1U76 A;  2AWA A;  1U7B A;  4TR6 A;  1B77 A;  2IZO B;  3A1J A;  1IZ4 A;  2HII B;  3FDS C;  2ZVL A;  3G65 A;  4D2G A;  3GGR C;  1PLQ A;  3A1J B;  1AXC A;  2Z0L A;  5IY4 A;  5IXA A;  2IZO C;  1B8H A;  2HII C;  1RWZ A;  3FDS D;  3IFV A;  2IX2 C;  3TBL A;  3I2M X;  5H0T A;  2NTI A;  3AIZ A;  5DAI A;  3A2F B;  3U5Z F;  4HK1 A;  3AIX B;  1RXM A;  1PLR A;  2OD8 A;  3P87 A;  2ZVK A;  3G65 B;  1GE8 A;  4L6P A;  3LX1 A;  1ISQ A;  2ZVV A;  5E0U A;  2AVT A;  5AUJ A;  3A1J C;  3WGW A;  1VYJ A;  5E0T A;  3U61 F;  2HIK A;  3G65 C;  3GPM A;  5CFK A;  3P91 A;  1W60 A;  4YHR A;  3LX2 A;  4CS5 A;  1RXZ A;  5DA7 A;  3HSL X;  2ZVM A;  3V61 B;  5E0V A;  2NTI B;  4L60 A;  5IWD A;  1DML A;  3F1W A;  1YYP A;  3U60 F;  1IZ5 A;  1UD9 A;  3K4X A;  1T6L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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