2HIKB

Heterotrimeric pcna sliding clamp
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
244
structure length
244
Chain Sequence
MKAKVIDAVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGFEVSQEKEIIGFKLEDVNDILKRVLKDDTLILSSNESKLTLTFDGEFTRSFELPLIQVESTQPPSVNLEFPFKAQLLTITFADIIDELSDLGEVLNIHSKENKLYFEVIGDLSTAKVELSTDNGTLLEASGADVSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRFKLPQEGYGDFYIAPRA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
pubmed doi rcsb
molecule tags Replication
source organism Sulfolobus solfataricus
molecule keywords PCNA1 (SSO0397)
total genus 55
structure length 244
sequence length 244
chains with identical sequence M, Y
ec nomenclature
pdb deposition date 2006-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
B PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2hikB00
1B8HA 3A1JA 3TBLA 2ZVMA 1RWZA 3V62B 1UD9A 3VKXA 1PLQA 3HI8A 3F1WA 2HIKC 2IZOB 1VYMA 2IX2B 1U76A 1VYJA 2HIKB 3P83A 3GPMA 2HIIA 3G65B 2AWAA 5HACA 3AIZC 3FDSC 2NTIA 4HK1A 3AIXA 5E0UA 3GGRA 3WGWA 2IZOC 5DAIA 5E0VA 3LX2A 4TR6A 2IX2C 1U7BA 1ISQA 2NTIB 4RJFA 3A1JC 3G65C 5B7OA 3GPNA 5JNED 4L6PA 2ZVVA 3A1JB 5A6DA 3LX1A 1CZDA 5E0TA 5IY4A 2ZVLA 1W60A 3FDSD 3U60F 2NTIC 3P87A 2AVTA 2HIIB 1IZ4A 2IO4A 3U61F 1UL1A 4ZTDA 3AIXB 3GGRC 4L60A 3HSLX 5H0TA 1GE8A 1PLRA 3I2MX 3GGRB 1RXZA 2IX2A 3V60B 2HIKA 1T6LA 5AUJA 4D2GA 3G65A 3A2FB 2HIIC 3K4XA 3U5ZF 2ZVKA 1AXCA 3P91A 5DA7A 1IZ5A 3AIZA 5IXAA 2IJXA 3IFVA 1RXMA 1B77A 2OD8A 5CFKA 1DMLA 2Z0LA 5IWDA 4CS5A 4YHRA 1YYPA 2ZVWA 1SXJF 2IO4B 3V61B
chains in the Genus database with same CATH superfamily
1B8HA 3A1JA 3TBLA 2ZVMA 1RWZA 3V62B 1UD9A 3VKXA 1PLQA 3HI8A 3F1WA 2HIKC 2IZOB 1VYMA 2IX2B 1U76A 1VYJA 2HIKB 3P83A 3GPMA 2HIIA 3G65B 2AWAA 5HACA 3AIZC 3FDSC 2NTIA 4HK1A 3AIXA 5E0UA 3GGRA 3WGWA 2IZOC 5DAIA 5E0VA 3LX2A 4TR6A 2IX2C 1U7BA 1ISQA 2NTIB 4RJFA 3A1JC 3G65C 5B7OA 3GPNA 5JNED 4L6PA 2ZVVA 3A1JB 5A6DA 3LX1A 1CZDA 5E0TA 5IY4A 2ZVLA 1W60A 3FDSD 3U60F 2NTIC 3P87A 2AVTA 2HIIB 1IZ4A 2IO4A 3U61F 1UL1A 4ZTDA 3AIXB 3GGRC 4L60A 3HSLX 5H0TA 1GE8A 1PLRA 3I2MX 3GGRB 1RXZA 2IX2A 3V60B 2HIKA 1T6LA 5AUJA 4D2GA 3G65A 3A2FB 2HIIC 3K4XA 3U5ZF 2ZVKA 1AXCA 3P91A 5DA7A 1IZ5A 3AIZA 5IXAA 2IJXA 3IFVA 1RXMA 1B77A 2OD8A 5CFKA 1DMLA 2Z0LA 5IWDA 4CS5A 4YHRA 1YYPA 2ZVWA 1SXJF 2IO4B 3V61B
chains in the Genus database with same CATH topology
1B8HA 3A1JA 3TBLA 2ZVMA 1RWZA 3V62B 1UD9A 3VKXA 1PLQA 3HI8A 3F1WA 2HIKC 2IZOB 1VYMA 2IX2B 1U76A 1VYJA 2HIKB 3P83A 3GPMA 2HIIA 3G65B 2AWAA 5HACA 3AIZC 3FDSC 2NTIA 4HK1A 3AIXA 5E0UA 3GGRA 3WGWA 2IZOC 5DAIA 5E0VA 3LX2A 4TR6A 2IX2C 1U7BA 1ISQA 2NTIB 4RJFA 3A1JC 3G65C 5B7OA 3GPNA 5JNED 4L6PA 2ZVVA 3A1JB 5A6DA 3LX1A 1CZDA 5E0TA 5IY4A 2ZVLA 1W60A 3FDSD 3U60F 2NTIC 3P87A 2AVTA 2HIIB 1IZ4A 2IO4A 3U61F 1UL1A 4ZTDA 3AIXB 3GGRC 4L60A 3HSLX 5H0TA 1GE8A 1PLRA 3I2MX 3GGRB 1RXZA 2IX2A 3V60B 2HIKA 1T6LA 5AUJA 4D2GA 3G65A 3A2FB 2HIIC 3K4XA 3U5ZF 2ZVKA 1AXCA 3P91A 5DA7A 1IZ5A 3AIZA 5IXAA 2IJXA 3IFVA 1RXMA 1B77A 2OD8A 5CFKA 1DMLA 2Z0LA 5IWDA 4CS5A 4YHRA 1YYPA 2ZVWA 1SXJF 2IO4B 3V61B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B8H A;  3A1J A;  3TBL A;  2ZVM A;  1RWZ A;  3V62 B;  1UD9 A;  3VKX A;  1PLQ A;  3HI8 A;  3F1W A;  2HIK C;  2IZO B;  1VYM A;  2IX2 B;  1U76 A;  1VYJ A;  2HIK B;  3P83 A;  3GPM A;  2HII A;  3G65 B;  2AWA A;  5HAC A;  3AIZ C;  3FDS C;  2NTI A;  4HK1 A;  3AIX A;  5E0U A;  3GGR A;  3WGW A;  2IZO C;  5DAI A;  5E0V A;  3LX2 A;  4TR6 A;  2IX2 C;  1U7B A;  1ISQ A;  2NTI B;  4RJF A;  3A1J C;  3G65 C;  5B7O A;  3GPN A;  5JNE D;  4L6P A;  2ZVV A;  3A1J B;  5A6D A;  3LX1 A;  1CZD A;  5E0T A;  5IY4 A;  2ZVL A;  1W60 A;  3FDS D;  3U60 F;  2NTI C;  3P87 A;  2AVT A;  2HII B;  1IZ4 A;  2IO4 A;  3U61 F;  1UL1 A;  4ZTD A;  3AIX B;  3GGR C;  4L60 A;  3HSL X;  5H0T A;  1GE8 A;  1PLR A;  3I2M X;  3GGR B;  1RXZ A;  2IX2 A;  3V60 B;  2HIK A;  1T6L A;  5AUJ A;  4D2G A;  3G65 A;  3A2F B;  2HII C;  3K4X A;  3U5Z F;  2ZVK A;  1AXC A;  3P91 A;  5DA7 A;  1IZ5 A;  3AIZ A;  5IXA A;  2IJX A;  3IFV A;  1RXM A;  1B77 A;  2OD8 A;  5CFK A;  1DML A;  2Z0L A;  5IWD A;  4CS5 A;  4YHR A;  1YYP A;  2ZVW A;  1SXJ F;  2IO4 B;  3V61 B; 
#chains in the Genus database with same CATH topology
 1B8H A;  3A1J A;  3TBL A;  2ZVM A;  1RWZ A;  3V62 B;  1UD9 A;  3VKX A;  1PLQ A;  3HI8 A;  3F1W A;  2HIK C;  2IZO B;  1VYM A;  2IX2 B;  1U76 A;  1VYJ A;  2HIK B;  3P83 A;  3GPM A;  2HII A;  3G65 B;  2AWA A;  5HAC A;  3AIZ C;  3FDS C;  2NTI A;  4HK1 A;  3AIX A;  5E0U A;  3GGR A;  3WGW A;  2IZO C;  5DAI A;  5E0V A;  3LX2 A;  4TR6 A;  2IX2 C;  1U7B A;  1ISQ A;  2NTI B;  4RJF A;  3A1J C;  3G65 C;  5B7O A;  3GPN A;  5JNE D;  4L6P A;  2ZVV A;  3A1J B;  5A6D A;  3LX1 A;  1CZD A;  5E0T A;  5IY4 A;  2ZVL A;  1W60 A;  3FDS D;  3U60 F;  2NTI C;  3P87 A;  2AVT A;  2HII B;  1IZ4 A;  2IO4 A;  3U61 F;  1UL1 A;  4ZTD A;  3AIX B;  3GGR C;  4L60 A;  3HSL X;  5H0T A;  1GE8 A;  1PLR A;  3I2M X;  3GGR B;  1RXZ A;  2IX2 A;  3V60 B;  2HIK A;  1T6L A;  5AUJ A;  4D2G A;  3G65 A;  3A2F B;  2HII C;  3K4X A;  3U5Z F;  2ZVK A;  1AXC A;  3P91 A;  5DA7 A;  1IZ5 A;  3AIZ A;  5IXA A;  2IJX A;  3IFV A;  1RXM A;  1B77 A;  2OD8 A;  5CFK A;  1DML A;  2Z0L A;  5IWD A;  4CS5 A;  4YHR A;  1YYP A;  2ZVW A;  1SXJ F;  2IO4 B;  3V61 B; 
#chains in the Genus database with same CATH homology
 1B8H A;  3A1J A;  3TBL A;  2ZVM A;  1RWZ A;  3V62 B;  1UD9 A;  3VKX A;  1PLQ A;  3HI8 A;  3F1W A;  2HIK C;  2IZO B;  1VYM A;  2IX2 B;  1U76 A;  1VYJ A;  2HIK B;  3P83 A;  3GPM A;  2HII A;  3G65 B;  2AWA A;  5HAC A;  3AIZ C;  3FDS C;  2NTI A;  4HK1 A;  3AIX A;  5E0U A;  3GGR A;  3WGW A;  2IZO C;  5DAI A;  5E0V A;  3LX2 A;  4TR6 A;  2IX2 C;  1U7B A;  1ISQ A;  2NTI B;  4RJF A;  3A1J C;  3G65 C;  5B7O A;  3GPN A;  5JNE D;  4L6P A;  2ZVV A;  3A1J B;  5A6D A;  3LX1 A;  1CZD A;  5E0T A;  5IY4 A;  2ZVL A;  1W60 A;  3FDS D;  3U60 F;  2NTI C;  3P87 A;  2AVT A;  2HII B;  1IZ4 A;  2IO4 A;  3U61 F;  1UL1 A;  4ZTD A;  3AIX B;  3GGR C;  4L60 A;  3HSL X;  5H0T A;  1GE8 A;  1PLR A;  3I2M X;  3GGR B;  1RXZ A;  2IX2 A;  3V60 B;  2HIK A;  1T6L A;  5AUJ A;  4D2G A;  3G65 A;  3A2F B;  2HII C;  3K4X A;  3U5Z F;  2ZVK A;  1AXC A;  3P91 A;  5DA7 A;  1IZ5 A;  3AIZ A;  5IXA A;  2IJX A;  3IFV A;  1RXM A;  1B77 A;  2OD8 A;  5CFK A;  1DML A;  2Z0L A;  5IWD A;  4CS5 A;  4YHR A;  1YYP A;  2ZVW A;  1SXJ F;  2IO4 B;  3V61 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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