2JAJA

Ddah1 complexed with l-257
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
274
structure length
272
Chain Sequence
AFGRATHAVVRALPESLGQHALRSGEEVDVARAERQHQLYVGVLGSKLGLQVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSMSELEKVDGLLTCCSVLINKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Disruption of methylarginine metabolism impairs vascular homeostasis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1
total genus 91
structure length 272
sequence length 274
chains with identical sequence B
ec nomenclature ec 3.5.3.18: Dimethylargininase.
pdb deposition date 2006-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2jajA00
1WD9A 2CI7A 2CI1A 2JAIA 4N2DA 2C6ZA 6JDWA 1ZBRA 2JAJA 3JDWA 3B1UA 4N24A 2EWOA 4YTBA 5AN9I 4N25A 2DW5A 2JERA 3RHYA 3APMA 1H70A 4X8CA 1JDXA 2CI6A 4N22A 3H7CX 4BOFA 4N2MA 4JDWA 2A9GA 5JDWA 4N2KA 7JDWA 5HP5A 4N2CA 4N28A 3APNA 3P8EA 2JDWA 2ABRA 4N26A 2JDXA 3P8PA 3B1TA 2CI5A 2DEYX 1WD8A 3HVMA 4N20A 1G62A 4N2IA 5AK7A 4N2BA 2CMUA 4N2LA 8JDWA 4N2AA 1XKNA 1S9RA 1G61A 1BWDA 2DEWX 3H7KA 1WDAA 1VKPA 4N2EA 5M3QA 2DEXX 4YTGA 4DKTA 2CI3A 4N2HA 3I2EA 9JDWA 4N2NA 1JDWA 3BPBA 4YT9A 4N2GA 2ACIA 3I4AA 2AAFA 4N2FA 1RXXA 5AK8A 4E4JA 4X8GA 2CI4A 2Q3UA 1LXYA
chains in the Genus database with same CATH superfamily
1WD9A 2CI7A 2CI1A 2JAIA 4N2DA 2C6ZA 6JDWA 1ZBRA 2JAJA 3JDWA 3B1UA 4N24A 2EWOA 4YTBA 5AN9I 4N25A 2DW5A 2JERA 3RHYA 3APMA 1H70A 4X8CA 1JDXA 2CI6A 4N22A 3H7CX 4BOFA 4N2MA 4JDWA 2A9GA 5JDWA 4N2KA 7JDWA 5HP5A 4N2CA 4N28A 3APNA 3P8EA 2JDWA 2ABRA 4N26A 2JDXA 3P8PA 1YNIA 3B1TA 2CI5A 1YNFA 2DEYX 1WD8A 3HVMA 4N20A 1G62A 4N2IA 5AK7A 1YNHA 4N2BA 2CMUA 4N2LA 8JDWA 4N2AA 1XKNA 1S9RA 1G61A 1BWDA 2DEWX 3H7KA 1WDAA 1VKPA 4N2EA 5M3QA 2DEXX 4YTGA 4DKTA 2CI3A 4N2HA 3I2EA 9JDWA 4N2NA 1JDWA 3BPBA 4YT9A 4N2GA 2ACIA 3I4AA 2AAFA 4N2FA 1RXXA 5AK8A 4E4JA 4X8GA 2CI4A 2Q3UA 1LXYA
chains in the Genus database with same CATH topology
1WD9A 2CI7A 2CI1A 2JAIA 4N2DA 2C6ZA 6JDWA 1ZBRA 2JAJA 3JDWA 3B1UA 4N24A 2EWOA 4YTBA 5AN9I 4N25A 2DW5A 2JERA 3RHYA 3APMA 1H70A 4X8CA 1JDXA 2CI6A 4N22A 3H7CX 4BOFA 4N2MA 4JDWA 2A9GA 5JDWA 4N2KA 7JDWA 5HP5A 4N2CA 4N28A 3APNA 3P8EA 2JDWA 2ABRA 4N26A 2JDXA 3P8PA 3B1TA 2CI5A 2DEYX 1WD8A 3HVMA 4N20A 1G62A 4N2IA 5AK7A 4N2BA 2CMUA 4N2LA 8JDWA 4N2AA 1XKNA 1S9RA 1G61A 1BWDA 2DEWX 3H7KA 1WDAA 1VKPA 4N2EA 5M3QA 2DEXX 4YTGA 4DKTA 2CI3A 4N2HA 3I2EA 9JDWA 4N2NA 1JDWA 3BPBA 4YT9A 4N2GA 2ACIA 3I4AA 2AAFA 4N2FA 1RXXA 5AK8A 4E4JA 4X8GA 2CI4A 2Q3UA 1LXYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WD9 A;  2CI7 A;  2CI1 A;  2JAI A;  4N2D A;  2C6Z A;  6JDW A;  1ZBR A;  2JAJ A;  3JDW A;  3B1U A;  4N24 A;  2EWO A;  4YTB A;  5AN9 I;  4N25 A;  2DW5 A;  2JER A;  3RHY A;  3APM A;  1H70 A;  4X8C A;  1JDX A;  2CI6 A;  4N22 A;  3H7C X;  4BOF A;  4N2M A;  4JDW A;  2A9G A;  5JDW A;  4N2K A;  7JDW A;  5HP5 A;  4N2C A;  4N28 A;  3APN A;  3P8E A;  2JDW A;  2ABR A;  4N26 A;  2JDX A;  3P8P A;  3B1T A;  2CI5 A;  2DEY X;  1WD8 A;  3HVM A;  4N20 A;  1G62 A;  4N2I A;  5AK7 A;  4N2B A;  2CMU A;  4N2L A;  8JDW A;  4N2A A;  1XKN A;  1S9R A;  1G61 A;  1BWD A;  2DEW X;  3H7K A;  1WDA A;  1VKP A;  4N2E A;  5M3Q A;  2DEX X;  4YTG A;  4DKT A;  2CI3 A;  4N2H A;  3I2E A;  9JDW A;  4N2N A;  1JDW A;  3BPB A;  4YT9 A;  4N2G A;  2ACI A;  3I4A A;  2AAF A;  4N2F A;  1RXX A;  5AK8 A;  4E4J A;  4X8G A;  2CI4 A;  2Q3U A;  1LXY A; 
#chains in the Genus database with same CATH topology
 1WD9 A;  2CI7 A;  2CI1 A;  2JAI A;  4N2D A;  2C6Z A;  6JDW A;  1ZBR A;  2JAJ A;  3JDW A;  3B1U A;  4N24 A;  2EWO A;  4YTB A;  5AN9 I;  4N25 A;  2DW5 A;  2JER A;  3RHY A;  3APM A;  1H70 A;  4X8C A;  1JDX A;  2CI6 A;  4N22 A;  3H7C X;  4BOF A;  4N2M A;  4JDW A;  2A9G A;  5JDW A;  4N2K A;  7JDW A;  5HP5 A;  4N2C A;  4N28 A;  3APN A;  3P8E A;  2JDW A;  2ABR A;  4N26 A;  2JDX A;  3P8P A;  1YNI A;  3B1T A;  2CI5 A;  1YNF A;  2DEY X;  1WD8 A;  3HVM A;  4N20 A;  1G62 A;  4N2I A;  5AK7 A;  1YNH A;  4N2B A;  2CMU A;  4N2L A;  8JDW A;  4N2A A;  1XKN A;  1S9R A;  1G61 A;  1BWD A;  2DEW X;  3H7K A;  1WDA A;  1VKP A;  4N2E A;  5M3Q A;  2DEX X;  4YTG A;  4DKT A;  2CI3 A;  4N2H A;  3I2E A;  9JDW A;  4N2N A;  1JDW A;  3BPB A;  4YT9 A;  4N2G A;  2ACI A;  3I4A A;  2AAF A;  4N2F A;  1RXX A;  5AK8 A;  4E4J A;  4X8G A;  2CI4 A;  2Q3U A;  1LXY A; 
#chains in the Genus database with same CATH homology
 1WD9 A;  2CI7 A;  2CI1 A;  2JAI A;  4N2D A;  2C6Z A;  6JDW A;  1ZBR A;  2JAJ A;  3JDW A;  3B1U A;  4N24 A;  2EWO A;  4YTB A;  5AN9 I;  4N25 A;  2DW5 A;  2JER A;  3RHY A;  3APM A;  1H70 A;  4X8C A;  1JDX A;  2CI6 A;  4N22 A;  3H7C X;  4BOF A;  4N2M A;  4JDW A;  2A9G A;  5JDW A;  4N2K A;  7JDW A;  5HP5 A;  4N2C A;  4N28 A;  3APN A;  3P8E A;  2JDW A;  2ABR A;  4N26 A;  2JDX A;  3P8P A;  3B1T A;  2CI5 A;  2DEY X;  1WD8 A;  3HVM A;  4N20 A;  1G62 A;  4N2I A;  5AK7 A;  4N2B A;  2CMU A;  4N2L A;  8JDW A;  4N2A A;  1XKN A;  1S9R A;  1G61 A;  1BWD A;  2DEW X;  3H7K A;  1WDA A;  1VKP A;  4N2E A;  5M3Q A;  2DEX X;  4YTG A;  4DKT A;  2CI3 A;  4N2H A;  3I2E A;  9JDW A;  4N2N A;  1JDW A;  3BPB A;  4YT9 A;  4N2G A;  2ACI A;  3I4A A;  2AAF A;  4N2F A;  1RXX A;  5AK8 A;  4E4J A;  4X8G A;  2CI4 A;  2Q3U A;  1LXY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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