2JDWA

Crystal structure and mechanism of l-arginine: glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
360
structure length
360
Chain Sequence
CPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords L-ARGININE\:GLYCINE AMIDINOTRANSFERASE
total genus 121
structure length 360
sequence length 360
ec nomenclature ec 2.1.4.1: Glycine amidinotransferase.
pdb deposition date 1997-01-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2jdwA00
2CI7A 4N2CA 3BPBA 1WDAA 2JAJA 2JDXA 3RHYA 4N2GA 2A9GA 3I4AA 3JDWA 1WD8A 2DW5A 1G61A 3I2EA 4X8GA 4JDWA 5HP5A 6JDWA 4N2KA 2ACIA 2DEWX 2JAIA 2JDWA 2DEYX 1BWDA 1S9RA 1ZBRA 7JDWA 3B1UA 4YT9A 1RXXA 3APMA 4YTBA 3APNA 1G62A 4N2EA 1JDWA 3B1TA 2C6ZA 2CI1A 2DEXX 4N20A 4N26A 4N2BA 5AK7A 1WD9A 4N2HA 4E4JA 4N24A 2Q3UA 4N2MA 1VKPA 4N2NA 1LXYA 4N25A 4N28A 3P8EA 2AAFA 4N2LA 2CI6A 4N2AA 5JDWA 2ABRA 5M3QA 2CMUA 9JDWA 3H7CX 1XKNA 4DKTA 3HVMA 8JDWA 3H7KA 5AK8A 1JDXA 4N2DA 5AN9I 4X8CA 2CI3A 4N2IA 4N2FA 3P8PA 2JERA 2EWOA 4N22A 4YTGA 4BOFA 1H70A 2CI5A 2CI4A
chains in the Genus database with same CATH superfamily
2CI7A 4N2CA 3BPBA 1WDAA 2JAJA 2JDXA 3RHYA 4N2GA 2A9GA 3I4AA 3JDWA 1WD8A 2DW5A 1G61A 3I2EA 4X8GA 4JDWA 5HP5A 6JDWA 4N2KA 2ACIA 2DEWX 2JAIA 2JDWA 2DEYX 1BWDA 1S9RA 1ZBRA 7JDWA 3B1UA 4YT9A 1RXXA 3APMA 4YTBA 3APNA 1G62A 4N2EA 1JDWA 3B1TA 2C6ZA 2CI1A 2DEXX 4N20A 4N26A 4N2BA 5AK7A 1WD9A 4N2HA 4E4JA 4N24A 2Q3UA 4N2MA 1VKPA 4N2NA 1LXYA 4N25A 1YNIA 4N28A 3P8EA 2AAFA 4N2LA 2CI6A 4N2AA 5JDWA 2ABRA 5M3QA 2CMUA 1YNFA 9JDWA 3H7CX 1XKNA 4DKTA 3HVMA 8JDWA 3H7KA 5AK8A 1JDXA 4N2DA 5AN9I 4X8CA 2CI3A 4N2IA 4N2FA 1YNHA 3P8PA 2JERA 2EWOA 4N22A 4YTGA 4BOFA 1H70A 2CI5A 2CI4A
chains in the Genus database with same CATH topology
2CI7A 4N2CA 3BPBA 1WDAA 2JAJA 2JDXA 3RHYA 4N2GA 2A9GA 3I4AA 3JDWA 1WD8A 2DW5A 1G61A 3I2EA 4X8GA 4JDWA 5HP5A 6JDWA 4N2KA 2ACIA 2DEWX 2JAIA 2JDWA 2DEYX 1BWDA 1S9RA 1ZBRA 7JDWA 3B1UA 4YT9A 1RXXA 3APMA 4YTBA 3APNA 1G62A 4N2EA 1JDWA 3B1TA 2C6ZA 2CI1A 2DEXX 4N20A 4N26A 4N2BA 5AK7A 1WD9A 4N2HA 4E4JA 4N24A 2Q3UA 4N2MA 1VKPA 4N2NA 1LXYA 4N25A 4N28A 3P8EA 2AAFA 4N2LA 2CI6A 4N2AA 5JDWA 2ABRA 5M3QA 2CMUA 9JDWA 3H7CX 1XKNA 4DKTA 3HVMA 8JDWA 3H7KA 5AK8A 1JDXA 4N2DA 5AN9I 4X8CA 2CI3A 4N2IA 4N2FA 3P8PA 2JERA 2EWOA 4N22A 4YTGA 4BOFA 1H70A 2CI5A 2CI4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CI7 A;  4N2C A;  3BPB A;  1WDA A;  2JAJ A;  2JDX A;  3RHY A;  4N2G A;  2A9G A;  3I4A A;  3JDW A;  1WD8 A;  2DW5 A;  1G61 A;  3I2E A;  4X8G A;  4JDW A;  5HP5 A;  6JDW A;  4N2K A;  2ACI A;  2DEW X;  2JAI A;  2JDW A;  2DEY X;  1BWD A;  1S9R A;  1ZBR A;  7JDW A;  3B1U A;  4YT9 A;  1RXX A;  3APM A;  4YTB A;  3APN A;  1G62 A;  4N2E A;  1JDW A;  3B1T A;  2C6Z A;  2CI1 A;  2DEX X;  4N20 A;  4N26 A;  4N2B A;  5AK7 A;  1WD9 A;  4N2H A;  4E4J A;  4N24 A;  2Q3U A;  4N2M A;  1VKP A;  4N2N A;  1LXY A;  4N25 A;  4N28 A;  3P8E A;  2AAF A;  4N2L A;  2CI6 A;  4N2A A;  5JDW A;  2ABR A;  5M3Q A;  2CMU A;  9JDW A;  3H7C X;  1XKN A;  4DKT A;  3HVM A;  8JDW A;  3H7K A;  5AK8 A;  1JDX A;  4N2D A;  5AN9 I;  4X8C A;  2CI3 A;  4N2I A;  4N2F A;  3P8P A;  2JER A;  2EWO A;  4N22 A;  4YTG A;  4BOF A;  1H70 A;  2CI5 A;  2CI4 A; 
#chains in the Genus database with same CATH topology
 2CI7 A;  4N2C A;  3BPB A;  1WDA A;  2JAJ A;  2JDX A;  3RHY A;  4N2G A;  2A9G A;  3I4A A;  3JDW A;  1WD8 A;  2DW5 A;  1G61 A;  3I2E A;  4X8G A;  4JDW A;  5HP5 A;  6JDW A;  4N2K A;  2ACI A;  2DEW X;  2JAI A;  2JDW A;  2DEY X;  1BWD A;  1S9R A;  1ZBR A;  7JDW A;  3B1U A;  4YT9 A;  1RXX A;  3APM A;  4YTB A;  3APN A;  1G62 A;  4N2E A;  1JDW A;  3B1T A;  2C6Z A;  2CI1 A;  2DEX X;  4N20 A;  4N26 A;  4N2B A;  5AK7 A;  1WD9 A;  4N2H A;  4E4J A;  4N24 A;  2Q3U A;  4N2M A;  1VKP A;  4N2N A;  1LXY A;  4N25 A;  1YNI A;  4N28 A;  3P8E A;  2AAF A;  4N2L A;  2CI6 A;  4N2A A;  5JDW A;  2ABR A;  5M3Q A;  2CMU A;  1YNF A;  9JDW A;  3H7C X;  1XKN A;  4DKT A;  3HVM A;  8JDW A;  3H7K A;  5AK8 A;  1JDX A;  4N2D A;  5AN9 I;  4X8C A;  2CI3 A;  4N2I A;  4N2F A;  1YNH A;  3P8P A;  2JER A;  2EWO A;  4N22 A;  4YTG A;  4BOF A;  1H70 A;  2CI5 A;  2CI4 A; 
#chains in the Genus database with same CATH homology
 2CI7 A;  4N2C A;  3BPB A;  1WDA A;  2JAJ A;  2JDX A;  3RHY A;  4N2G A;  2A9G A;  3I4A A;  3JDW A;  1WD8 A;  2DW5 A;  1G61 A;  3I2E A;  4X8G A;  4JDW A;  5HP5 A;  6JDW A;  4N2K A;  2ACI A;  2DEW X;  2JAI A;  2JDW A;  2DEY X;  1BWD A;  1S9R A;  1ZBR A;  7JDW A;  3B1U A;  4YT9 A;  1RXX A;  3APM A;  4YTB A;  3APN A;  1G62 A;  4N2E A;  1JDW A;  3B1T A;  2C6Z A;  2CI1 A;  2DEX X;  4N20 A;  4N26 A;  4N2B A;  5AK7 A;  1WD9 A;  4N2H A;  4E4J A;  4N24 A;  2Q3U A;  4N2M A;  1VKP A;  4N2N A;  1LXY A;  4N25 A;  4N28 A;  3P8E A;  2AAF A;  4N2L A;  2CI6 A;  4N2A A;  5JDW A;  2ABR A;  5M3Q A;  2CMU A;  9JDW A;  3H7C X;  1XKN A;  4DKT A;  3HVM A;  8JDW A;  3H7K A;  5AK8 A;  1JDX A;  4N2D A;  5AN9 I;  4X8C A;  2CI3 A;  4N2I A;  4N2F A;  3P8P A;  2JER A;  2EWO A;  4N22 A;  4YTG A;  4BOF A;  1H70 A;  2CI5 A;  2CI4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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