2KIEA

A ph domain within ocrl bridges clathrin mediated membrane trafficking to phosphoinositide metabolis
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
124
structure length
124
Chain Sequence
GPLGSMEPPLPVGAQPLATVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Inositol polyphosphate 5-phosphatase OCRL-1
total genus 17
structure length 124
sequence length 124
ec nomenclature ec 3.1.3.36: Phosphoinositide 5-phosphatase.
pdb deposition date 2009-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16726 OCRL_clath_bd Inositol polyphosphate 5-phosphatase clathrin binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.110 Mainly Beta Roll PH-domain like PH-domain like 2kieA00
2KIGA 2KIEA
chains in the Genus database with same CATH superfamily
4TYZA 2J0KA 2W2XD 3NWDA 3KRWA 5J3QA 2ELBA 5C6RA 1X11A 2RLOA 2Z59A 3CIKA 2FJLA 1XCGA 3FVCA 1DDMA 3AU5A 1W1GA 2HTHB 2Q13A 3CXBB 3FSSA 5HE1A 4CSQA 2YT2A 2D11A 2DX1A 3ULCA 5KQ1A 5D3XA 1QQGA 1ZYIA 2LULA 4QJ5B 2N0YA 1Y19B 2K2JA 4ZRIA 2RVBB 2EMTA 1E5WA 5JLJB 2IFSA 2DKPA 1H10A 2X18A 3MDBC 3TFMA 1AQCA 2RUKB 4HDQA 2J0MA 3LJUX 1MIXA 4GMXB 1U5FA 3KZ1A 3PSCA 2MFQA 3TO1A 1Y5OA 3X23A 2LKOA 1U5GA 2KGXB 2CRFA 4HAYB 4GNKB 2K8EA 3PZDA 1V61A 2ELAA 2M14A 3PVLA 2D9ZA 2P0DA 2D9WA 1Z87A 1I7AA 1DYNA 1NU2A 1TQZA 2ROZB 2GJYA 3VIAA 2GCJA 5C5BA 3GYOA 1U29A 4WJ7A 1GC7A 4PNKA 1BAKA 2I1KA 4MK0A 2DFKA 1DDWA 1FGZA 2QKMA 3A8QA 3N7CA 1PMSA 2GS0A 5FI1A 2NZ8B 4HB4B 4NSWA 5LG4B 3M1IB 1EGXA 1ZVRA 3PVWA 1OQNA 1J19A 1EAZA 3AU4A 4D0NB 2COFA 5D3VA 2DN6A 1W1DA 2D2QA 2AL6A 1NTYA 3OANA 1UNPA 4EMOA 2CODA 3PP2A 2LOZA 2OQBA 2IYBA 4IOYX 4WSFA 1U5EA 1LB1A 5HE0A 4WVFB 2D9VA 1UPQA 2I1JA 1FHXA 4K2PA 3DXDA 3BJIA 2DHJA 2Y8FA 3KY9A 5GOWB 2Z0OA 4KAXB 2HE7A 2ROVA 2DLWA 4A6FA 1UPRA 4GOUA 2UZRA 3IVFA 3SV1A 1FOEA 2UZSA 1V88A 5I2MA 4L1RA 3QIJA 2KIEA 4K81A 1AWEA 4GPTB 2Z14A 3B77A 1GG3A 3HK0A 1V89A 1ZSQA 2DX5A 4HAZB 3BINA 1LW3A 3A8PA 5D27A 2MWNB 2Y7BA 5CLLB 4KHBB 2Z0QA 5HE2A 2M38A 1SGHA 3QBVB 1M7EA 2VKIA 3F0WA 3V5WA 5DH9B 2DYNA 4DIXA 5HE3A 5C79A 1ZM0A 2PZ1A 4Y94A 4GZUA 4K17A 1NI2A 3ODOA 3ZVRA 1WI1A 2EC1A 1M7RA 2Z13A 1W1HA 4GXBA 3VOQA 4A5KA 2AEHA 3F5RA 4PQ0A 2ZKMX 3MPXA 3U8ZA 5JHHA 3PVUA 1MK7B 4Z2NA 4KHOA 2NBVA 3TVVA 2R0DA 2YT1A 1MAIA 2W2WA 4K2OA 2EJ8A 4BBKA 4QJ4B 4CHMA 2D10A 4CYEA 4IAPA 2GUMA 2J59M 2KUPA 2DA0A 2OTXA 1P6SA 3PG7A 2D9XA 2Z0PA 2Y8GA 2YS1A 2D9YA 1OMWA 3KSYA 2E2XA 5L81A 1BWNA 1GC6A 4DXAB 1TXDA 2V76A 4HB0B 4KVGB 2EMSA 4YONA 1BTNA 1KI1B 1BTKA 1XKEA 4EKUA 4EJNA 3KRXA 2KR0A 2ZPYA 2P8VA 5D3WA 5I2SA 3FEHA 4A6HA 1WJ1A 1XODA 4HDOA 3P6AA 1WJMA 1P5TA 5D3YA 2XQNM 1RRPB 1WG7A 1WGUA 4KHBA 2KUQA 2QKLA 3AJ4A 4F7GA 2R2YA 3A58A 1H4RA 2CAYA 3HW2B 4GN1A 5J3YA 2DHKA 2YT0A 5JP4A 4HAVB 1Q67A 1FB8A 1X86A 1T77A 3PEGA 4YL8A 3SUZA 1B55A 5DHFB 1KZ7A 1X05A 2ADZA 3U12A 3HSAA 3T06A 1UNRA 5JHGA 1WVHA 3QWMA 3TCAA 4C0AA 2MDXA 4ZRKA 2P0FA 2D4QA 3TW1A 3ZDTA 1MI1A 2FJUB 3A98B 1XD4A 4HB2B 1V5PA 1IRSA 4KHAA 3OHMB 5C5BB 2K00A 1MIZB 1I2HA 3P7ZA 2DKQA 1SHCA 4XWXA 4QXAB 4HATB 2YS3A 1ISNA 3ULBA 1EF1A 5DHAB 3DXCA 5DIFB 2K2UA 4HB3B 1FHOA 2R09A 5M4YB 2LG1A 2N23A 2J0JA 2COCA 3ML4A 4L6EA 4OSNA 4HAUB 3WYFB 1EVHA 4ZRJA 5KQ4A 3WA0A 1PFJA 2CY4A 1UEFA 4IFSA 2NMBA 2LOXA 1XR0B 3NWFA 5KCVA 2RSGA 5DI9B 3G9WA 1DBHA 3D8FA 3RCPA 2VRWB 1XX0A 2H7DA 5LOPB 1DROA 3D8DA 4NY0A 4MY6A 4P7IA 1DDVA 2YS5A 1MPHA 1TJ6A 4DBBA 4HSIA 2YRYA 4B6HA 5FI0A 4A6FB 1RJ2A 2W2XC 1FGYA 1MKEA 3NWAA 1NTVA 3GYPA 1PLSA 2I5CA 3D8EA 2P0HA 1J0WA 2UVMA 1FAOA 4DX8A 2H7EA 2RRFA 3ODXA 4OT1A 2KCJA 1FHWA 1ZC3B 1V5MA 4HHVA 1U5DA 1V5UA 2JP2A 4QJ3B 2DTCA 2VSZA 1KZGA 1U27A 2RNRB 1X1FA 3O96A 3ODWA 3HQCA 2K49A 4MT7A 4HAXB 1MK9B 2CY5A 4H8SA 4TKNA 2BCJA 5LONB 1K5DB 5EFXA 1U2BA 2MKRA 1WGQA 2YF0A 1OY2A 2DHIA 4GMVA 5J3TA 3U7DA 4F7HA 2G35A 2RGNB 2Z4DA 3UZTA 3SO6A 1X1GA 4Z2MB 4DX90 1P3RA 2L1CA 5C16A 2GCLA 3SNHA 3NW8A 4F7UP 1K5GB 4A6KA 2L2IA 2KIGA 3DCXA 3SYXA 3HIEA 2LYDA 4CHJA 2COAA 5CLQB 2I5FA 4D6WA 3FM8C 2YSZA 1UNQA 1QC6A 1ZC4B 3DXEA 3NSUA 4HAWB 1N3HA 2DYQA 2YVCA 5IRSA
chains in the Genus database with same CATH topology
4Z2MB 4KHBA 4Z2NA 4KHOA 2KUQA 3TO1A 2NBVA 3TVVA 2R2YA 4GOUA 3NWDA 3GYPA 3NWAA 3A58A 2GCLA 2K49A 3NWFA 4L1RA 5I2MA 3NW8A 2KIEA 4GNKB 4DIXA 2K8EA 2Z14A 3TW1A 2Z59A 2KIGA 5M4YB 3HIEA 4QJ4B 3FVCA 2FJUB 2KR0A 2GUMA 4IOYX 2RRFA 3FSSA 4CSQA 4D6WA 5I2SA 2YT2A 4KHAA 5LG4B 4OT1A 3OHMB 4OSNA 3U12A 2Z13A 1ZYIA 4HSIA 2GCJA 3GYOA 4QJ3B 4KHBB 4QXAB 4PQ0A 2ZKMX 5IRSA 2Z4DA 4QJ5B 4IFSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KIG A;  2KIE A; 
#chains in the Genus database with same CATH topology
 4TYZ A;  2J0K A;  2W2X D;  3NWD A;  3KRW A;  5J3Q A;  2ELB A;  5C6R A;  1X11 A;  2RLO A;  2Z59 A;  3CIK A;  2FJL A;  1XCG A;  3FVC A;  1DDM A;  3AU5 A;  1W1G A;  2HTH B;  2Q13 A;  3CXB B;  3FSS A;  5HE1 A;  4CSQ A;  2YT2 A;  2D11 A;  2DX1 A;  3ULC A;  5KQ1 A;  5D3X A;  1QQG A;  1ZYI A;  2LUL A;  4QJ5 B;  2N0Y A;  1Y19 B;  2K2J A;  4ZRI A;  2RVB B;  2EMT A;  1E5W A;  5JLJ B;  2IFS A;  2DKP A;  1H10 A;  2X18 A;  3MDB C;  3TFM A;  1AQC A;  2RUK B;  4HDQ A;  2J0M A;  3LJU X;  1MIX A;  4GMX B;  1U5F A;  3KZ1 A;  3PSC A;  2MFQ A;  3TO1 A;  1Y5O A;  3X23 A;  2LKO A;  1U5G A;  2KGX B;  2CRF A;  4HAY B;  4GNK B;  2K8E A;  3PZD A;  1V61 A;  2ELA A;  2M14 A;  3PVL A;  2D9Z A;  2P0D A;  2D9W A;  1Z87 A;  1I7A A;  1DYN A;  1NU2 A;  1TQZ A;  2ROZ B;  2GJY A;  3VIA A;  2GCJ A;  5C5B A;  3GYO A;  1U29 A;  4WJ7 A;  1GC7 A;  4PNK A;  1BAK A;  2I1K A;  4MK0 A;  2DFK A;  1DDW A;  1FGZ A;  2QKM A;  3A8Q A;  3N7C A;  1PMS A;  2GS0 A;  5FI1 A;  2NZ8 B;  4HB4 B;  4NSW A;  5LG4 B;  3M1I B;  1EGX A;  1ZVR A;  3PVW A;  1OQN A;  1J19 A;  1EAZ A;  3AU4 A;  4D0N B;  2COF A;  5D3V A;  2DN6 A;  1W1D A;  2D2Q A;  2AL6 A;  1NTY A;  3OAN A;  1UNP A;  4EMO A;  2COD A;  3PP2 A;  2LOZ A;  2OQB A;  2IYB A;  4IOY X;  4WSF A;  1U5E A;  1LB1 A;  5HE0 A;  4WVF B;  2D9V A;  1UPQ A;  2I1J A;  1FHX A;  4K2P A;  3DXD A;  3BJI A;  2DHJ A;  2Y8F A;  3KY9 A;  5GOW B;  2Z0O A;  4KAX B;  2HE7 A;  2ROV A;  2DLW A;  4A6F A;  1UPR A;  4GOU A;  2UZR A;  3IVF A;  3SV1 A;  1FOE A;  2UZS A;  1V88 A;  5I2M A;  4L1R A;  3QIJ A;  2KIE A;  4K81 A;  1AWE A;  4GPT B;  2Z14 A;  3B77 A;  1GG3 A;  3HK0 A;  1V89 A;  1ZSQ A;  2DX5 A;  4HAZ B;  3BIN A;  1LW3 A;  3A8P A;  5D27 A;  2MWN B;  2Y7B A;  5CLL B;  4KHB B;  2Z0Q A;  5HE2 A;  2M38 A;  1SGH A;  3QBV B;  1M7E A;  2VKI A;  3F0W A;  3V5W A;  5DH9 B;  2DYN A;  4DIX A;  5HE3 A;  5C79 A;  1ZM0 A;  2PZ1 A;  4Y94 A;  4GZU A;  4K17 A;  1NI2 A;  3ODO A;  3ZVR A;  1WI1 A;  2EC1 A;  1M7R A;  2Z13 A;  1W1H A;  4GXB A;  3VOQ A;  4A5K A;  2AEH A;  3F5R A;  4PQ0 A;  2ZKM X;  3MPX A;  3U8Z A;  5JHH A;  3PVU A;  1MK7 B;  4Z2N A;  4KHO A;  2NBV A;  3TVV A;  2R0D A;  2YT1 A;  1MAI A;  2W2W A;  4K2O A;  2EJ8 A;  4BBK A;  4QJ4 B;  4CHM A;  2D10 A;  4CYE A;  4IAP A;  2GUM A;  2J59 M;  2KUP A;  2DA0 A;  2OTX A;  1P6S A;  3PG7 A;  2D9X A;  2Z0P A;  2Y8G A;  2YS1 A;  2D9Y A;  1OMW A;  3KSY A;  2E2X A;  5L81 A;  1BWN A;  1GC6 A;  4DXA B;  1TXD A;  2V76 A;  4HB0 B;  4KVG B;  2EMS A;  4YON A;  1BTN A;  1KI1 B;  1BTK A;  1XKE A;  4EKU A;  4EJN A;  3KRX A;  2KR0 A;  2ZPY A;  2P8V A;  5D3W A;  5I2S A;  3FEH A;  4A6H A;  1WJ1 A;  1XOD A;  4HDO A;  3P6A A;  1WJM A;  1P5T A;  5D3Y A;  2XQN M;  1RRP B;  1WG7 A;  1WGU A;  4KHB A;  2KUQ A;  2QKL A;  3AJ4 A;  4F7G A;  2R2Y A;  3A58 A;  1H4R A;  2CAY A;  3HW2 B;  4GN1 A;  5J3Y A;  2DHK A;  2YT0 A;  5JP4 A;  4HAV B;  1Q67 A;  1FB8 A;  1X86 A;  1T77 A;  3PEG A;  4YL8 A;  3SUZ A;  1B55 A;  5DHF B;  1KZ7 A;  1X05 A;  2ADZ A;  3U12 A;  3HSA A;  3T06 A;  1UNR A;  5JHG A;  1WVH A;  3QWM A;  3TCA A;  4C0A A;  2MDX A;  4ZRK A;  2P0F A;  2D4Q A;  3TW1 A;  3ZDT A;  1MI1 A;  2FJU B;  3A98 B;  1XD4 A;  4HB2 B;  1V5P A;  1IRS A;  4KHA A;  3OHM B;  5C5B B;  2K00 A;  1MIZ B;  1I2H A;  3P7Z A;  2DKQ A;  1SHC A;  4XWX A;  4QXA B;  4HAT B;  2YS3 A;  1ISN A;  3ULB A;  1EF1 A;  5DHA B;  3DXC A;  5DIF B;  2K2U A;  4HB3 B;  1FHO A;  2R09 A;  5M4Y B;  2LG1 A;  2N23 A;  2J0J A;  2COC A;  3ML4 A;  4L6E A;  4OSN A;  4HAU B;  3WYF B;  1EVH A;  4ZRJ A;  5KQ4 A;  3WA0 A;  1PFJ A;  2CY4 A;  1UEF A;  4IFS A;  2NMB A;  2LOX A;  1XR0 B;  3NWF A;  5KCV A;  2RSG A;  5DI9 B;  3G9W A;  1DBH A;  3D8F A;  3RCP A;  2VRW B;  1XX0 A;  2H7D A;  5LOP B;  1DRO A;  3D8D A;  4NY0 A;  4MY6 A;  4P7I A;  1DDV A;  2YS5 A;  1MPH A;  1TJ6 A;  4DBB A;  4HSI A;  2YRY A;  4B6H A;  5FI0 A;  4A6F B;  1RJ2 A;  2W2X C;  1FGY A;  1MKE A;  3NWA A;  1NTV A;  3GYP A;  1PLS A;  2I5C A;  3D8E A;  2P0H A;  1J0W A;  2UVM A;  1FAO A;  4DX8 A;  2H7E A;  2RRF A;  3ODX A;  4OT1 A;  2KCJ A;  1FHW A;  1ZC3 B;  1V5M A;  4HHV A;  1U5D A;  1V5U A;  2JP2 A;  4QJ3 B;  2DTC A;  2VSZ A;  1KZG A;  1U27 A;  2RNR B;  1X1F A;  3O96 A;  3ODW A;  3HQC A;  2K49 A;  4MT7 A;  4HAX B;  1MK9 B;  2CY5 A;  4H8S A;  4TKN A;  2BCJ A;  5LON B;  1K5D B;  5EFX A;  1U2B A;  2MKR A;  1WGQ A;  2YF0 A;  1OY2 A;  2DHI A;  4GMV A;  5J3T A;  3U7D A;  4F7H A;  2G35 A;  2RGN B;  2Z4D A;  3UZT A;  3SO6 A;  1X1G A;  4Z2M B;  4DX9 0;  1P3R A;  2L1C A;  5C16 A;  2GCL A;  3SNH A;  3NW8 A;  4F7U P;  1K5G B;  4A6K A;  2L2I A;  2KIG A;  3DCX A;  3SYX A;  3HIE A;  2LYD A;  4CHJ A;  2COA A;  5CLQ B;  2I5F A;  4D6W A;  3FM8 C;  2YSZ A;  1UNQ A;  1QC6 A;  1ZC4 B;  3DXE A;  3NSU A;  4HAW B;  1N3H A;  2DYQ A;  2YVC A;  5IRS A; 
#chains in the Genus database with same CATH homology
 4Z2M B;  4KHB A;  4Z2N A;  4KHO A;  2KUQ A;  3TO1 A;  2NBV A;  3TVV A;  2R2Y A;  4GOU A;  3NWD A;  3GYP A;  3NWA A;  3A58 A;  2GCL A;  2K49 A;  3NWF A;  4L1R A;  5I2M A;  3NW8 A;  2KIE A;  4GNK B;  4DIX A;  2K8E A;  2Z14 A;  3TW1 A;  2Z59 A;  2KIG A;  5M4Y B;  3HIE A;  4QJ4 B;  3FVC A;  2FJU B;  2KR0 A;  2GUM A;  4IOY X;  2RRF A;  3FSS A;  4CSQ A;  4D6W A;  5I2S A;  2YT2 A;  4KHA A;  5LG4 B;  4OT1 A;  3OHM B;  4OSN A;  3U12 A;  2Z13 A;  1ZYI A;  4HSI A;  2GCJ A;  3GYO A;  4QJ3 B;  4KHB B;  4QXA B;  4PQ0 A;  2ZKM X;  5IRS A;  2Z4D A;  4QJ5 B;  4IFS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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