2LKOA

Structural basis of phosphoinositide binding to kindlin-2 pleckstrin homology domain in regulating integrin activation
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
138
structure length
138
Chain Sequence
GSHMGDITSIPELADYIKVFKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAACRLASKGKTMADSSYNLEVQNILSFLKMQH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation.
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords Fermitin family homolog 2
total genus 15
structure length 138
sequence length 138
ec nomenclature
pdb deposition date 2011-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2lkoA00
5CLLB 2AEHA 3T06A 4A5KA 4K2PA 1U5GA 2KUPA 4MT7A 3RCPA 4MK0A 4F7GA 1XKEA 2J0JA 1BAKA 5DI9B 1TJ6A 4HB4B 1P6SA 4NY0A 4DBBA 3D8EA 3SV1A 1H10A 3MPXA 1FGYA 3NSUA 1PLSA 1V5UA 4ZRKA 2J59M 1MIZB 2I1KA 2I1JA 3A8PA 1MK7B 5J3TA 2DA0A 1XCGA 2DLWA 5D3XA 2KCJA 1KZ7A 5KCVA 2DHIA 5DHAB 2HE7A 1MAIA 2LOXA 2NZ8B 5HE0A 5HE1A 2ZPYA 1V5PA 2P8VA 2W2WA 1OMWA 5C79A 3BINA 4B6HA 1RRPB 5J3YA 1NI2A 1MK9B 2AL6A 3WA0A 1FHOA 2D9ZA 1DYNA 2Q13A 2YRYA 2J0KA 5C5BA 1TXDA 2H7DA 3PSCA 2MKRA 4HAZB 2RUKB 1RJ2A 3M1IB 1V88A 1I2HA 2YT1A 1K5GB 1OQNA 3G9WA 2P0FA 2YF0A 3HW2B 5JHHA 3N7CA 3TCAA 3OANA 3A8QA 1WJMA 3TFMA 1FHXA 2X18A 4GXBA 3V5WA 3TO1A 1N3HA 3GYPA 5D3WA 2L2IA 1DROA 5EFXA 5JP4A 1U29A 2RVBB 1U5FA 5LONB 1P3RA 5D27A 1PFJA 2ADZA 4EMOA 4GN1A 2CAYA 4WVFB 5C6RA 5GOWB 3PZDA 4GMVA 3VOQA 4P7IA 2YT0A 2OTXA 3U7DA 1WGUA 3VIAA 1GC6A 2D9WA 1H4RA 2YSZA 1X1FA 1EVHA 2D9YA 2R0DA 2Y8FA 4F7HA 4D0NB 3HK0A 2DKQA 3P6AA 4YONA 4HDQA 2YS5A 3LJUX 5KQ4A 4HAXB 3DXEA 1EF1A 2LG1A 2J0MA 4KHAA 1BTKA 1X05A 2FJLA 5KQ1A 1AQCA 2COFA 2EMSA 4HAWB 4DXAB 2DX5A 4CHMA 2GS0A 2V76A 2P0DA 2XQNM 4L6EA 3CIKA 1M7EA 5LOPB 1UNPA 1ZM0A 4C0AA 2H7EA 1FAOA 1MPHA 4IAPA 3X23A 2Y7BA 1W1GA 5FI0A 4Z2NA 2P0HA 3DXCA 3PVWA 5L81A 4A6FB 1FOEA 5DIFB 2PZ1A 2IFSA 1BWNA 1W1HA 1GG3A 1I7AA 2NMBA 1Y5OA 2CODA 4HAVB 4Z2MB 4BBKA 3SUZA 2VSZA 4K17A 3KRXA 1Z87A 1OY2A 1B55A 2BCJA 1QC6A 4A6FA 2N23A 1U5DA 3F0WA 4HHVA 4ZRJA 2W2XC 3HQCA 2UVMA 4GMXB 2G35A 2KGXB 2DYQA 2YS1A 3PVUA 3AU4A 1KZGA 4NSWA 2EMTA 1X86A 2R09A 4KAXB 1FHWA 1WG7A 1FGZA 1ZVRA 2GCLA 3FM8C 4IOYX 3ZVRA 5JHGA 1WVHA 4MY6A 2LYDA 1U5EA 3ODXA 3SNHA 3QBVB 3TW1A 1UNRA 1LB1A 3TVVA 3UZTA 2RSGA 4HATB 4PQ0A 1XR0B 3QIJA 1IRSA 3SO6A 2CRFA 3GYOA 2MFQA 1K5DB 4ZRIA 5DH9B 2DHJA 3QWMA 2K2JA 4CHJA 4A6HA 1DDWA 3ULBA 3CXBB 1P5TA 3ZDTA 2RLOA 1XD4A 1MIXA 4TKNA 2EJ8A 1Q67A 3DXDA 2I5FA 1WJ1A 2GCJA 2OQBA 2DN6A 2K00A 3SYXA 2Z0QA 4WSFA 1UNQA 3A98B 5J3QA 5JLJB 1XODA 1AWEA 4K81A 4F7UP 1LW3A 1U27A 3ODWA 3WYFB 1WGQA 2CY5A 1V5MA 4KVGB 5D3YA 2D10A 4HAUB 1SGHA 5HE2A 2DTCA 2CY4A 2MWNB 1ZC4B 1EAZA 5D3VA 2LKOA 3PP2A 1ZSQA 4HB3B 1SHCA 3ULCA 4EJNA 1KI1B 1UPRA 4KHBB 2VRWB 3BJIA 1XX0A 4H8SA 2M14A 1NTYA 2JP2A 2LULA 1X11A 1J0WA 3PEGA 4HB2B 2D11A 1QQGA 2I5CA 3ML4A 5C5BB 1X1GA 2HTHB 2GJYA 3KSYA 3AU5A 2D9XA 4KHOA 2ELBA 3ODOA 2ROZB 1V61A 4GPTB 1ISNA 1BTNA 1U2BA 4Y94A 1FB8A 2W2XD 2D4QA 2YS3A 2DYNA 3MDBC 5CLQB 1ZC3B 1UPQA 2DHKA 3IVFA 2COCA 5DHFB 2ELAA 4TYZA 1J19A 2D2QA 2QKLA 2N0YA 4HB0B 3KY9A 3KZ1A 2UZSA 3O96A 1W1DA 2E2XA 1MKEA 2UZRA 2EC1A 3FEHA 1Y19B 2IYBA 4GZUA 2DFKA 1WI1A 1V89A 4A6KA 3PVLA 1E5WA 4WJ7A 1TQZA 4HDOA 3PG7A 3F5RA 1M7RA 2COAA 2K2UA 3P7ZA 5FI1A 3D8DA 2VKIA 2Z0OA 3D8FA 5HE3A 3U8ZA 1DDMA 1DBHA 4HAYB 5C16A 2ROVA 2RGNB 2YVCA 1NU2A 4K2OA 2L1CA 3AJ4A 3KRWA 4IFSA 2QKMA 4DX8A 2Z0PA 1NTVA 4YL8A 1PMSA 4EKUA 4XWXA 2LOZA 2MDXA 1GC7A 2RNRB 1UEFA 2M38A 2Y8GA 2DKPA 2DX1A 4PNKA 1EGXA 4CYEA 1DDVA 3FSSA 2D9VA 4DX90
chains in the Genus database with same CATH superfamily
5CLLB 2AEHA 3T06A 4A5KA 4K2PA 1U5GA 2KUPA 4MT7A 3RCPA 4MK0A 4F7GA 1XKEA 2J0JA 4OSNA 3NWDA 1BAKA 5DI9B 1TJ6A 4HB4B 1P6SA 4NY0A 4DBBA 3D8EA 3SV1A 1H10A 2Z59A 3MPXA 1FGYA 3NSUA 1PLSA 1V5UA 4ZRKA 2J59M 1MIZB 2I1KA 2I1JA 3A8PA 1MK7B 5J3TA 2DA0A 1XCGA 2DLWA 5D3XA 2KCJA 1KZ7A 5KCVA 2DHIA 5DHAB 2HE7A 1MAIA 2LOXA 2NZ8B 5HE0A 5HE1A 2ZPYA 1V5PA 2P8VA 2W2WA 1OMWA 5C79A 3BINA 4B6HA 4KHBA 1RRPB 5J3YA 1NI2A 3FVCA 1MK9B 2AL6A 3WA0A 2FJUB 1FHOA 2D9ZA 1DYNA 2Q13A 2YRYA 4QJ3B 2J0KA 5C5BA 1TXDA 2H7DA 3NWFA 3PSCA 2MKRA 3HSAA 4HAZB 2RUKB 1RJ2A 3M1IB 1V88A 1I2HA 2YT1A 1K5GB 1OQNA 2YT2A 3G9WA 2P0FA 2YF0A 3HW2B 5JHHA 3N7CA 3TCAA 3OANA 3A8QA 1WJMA 3TFMA 1FHXA 2X18A 4GXBA 3V5WA 3TO1A 1N3HA 4CSQA 3GYPA 2Z14A 5D3WA 2L2IA 1DROA 5EFXA 5JP4A 1U29A 2KIEA 2RVBB 1U5FA 5LONB 3HIEA 1P3RA 5D27A 1PFJA 2ADZA 4EMOA 4GN1A 2CAYA 3NWAA 4WVFB 5C6RA 5GOWB 3PZDA 4GMVA 3VOQA 4P7IA 2YT0A 3A58A 2OTXA 4QXAB 3U7DA 1WGUA 3VIAA 1GC6A 2D9WA 1H4RA 2YSZA 1X1FA 1EVHA 2D9YA 2K49A 2R0DA 2Y8FA 4F7HA 4D0NB 3U12A 2Z4DA 3HK0A 2DKQA 3P6AA 4YONA 4HDQA 2YS5A 3LJUX 5KQ4A 4D6WA 4HAXB 3DXEA 1EF1A 3NW8A 2LG1A 2J0MA 4KHAA 4OT1A 1BTKA 1X05A 2FJLA 5KQ1A 1AQCA 2COFA 2EMSA 4HAWB 4DXAB 2DX5A 2KR0A 4CHMA 2GS0A 2V76A 2P0DA 2KIGA 2XQNM 4L6EA 3CIKA 1M7EA 5LOPB 1UNPA 1ZM0A 4C0AA 2H7EA 1FAOA 1MPHA 4IAPA 3X23A 2Y7BA 1W1GA 5FI0A 4Z2NA 2P0HA 3DXCA 3PVWA 5L81A 4A6FB 1FOEA 5DIFB 2PZ1A 2IFSA 2K8EA 1BWNA 1W1HA 1GG3A 1I7AA 2NMBA 1Y5OA 2CODA 4HAVB 4QJ5B 4Z2MB 4BBKA 3SUZA 2VSZA 4K17A 3KRXA 1Z87A 1OY2A 1B55A 2BCJA 1QC6A 4A6FA 5IRSA 2N23A 1U5DA 4L1RA 3F0WA 4HHVA 4ZRJA 2W2XC 3HQCA 2UVMA 4GMXB 2G35A 2KGXB 2DYQA 2YS1A 3PVUA 3AU4A 1KZGA 4NSWA 3DCXA 2EMTA 2R2YA 1X86A 2KUQA 2R09A 4KAXB 1FHWA 1WG7A 1FGZA 1ZVRA 2GCLA 3FM8C 4IOYX 3ZVRA 5JHGA 1WVHA 4MY6A 2LYDA 1U5EA 2Z13A 3ODXA 3SNHA 3QBVB 3TW1A 1UNRA 1LB1A 3TVVA 3UZTA 2RSGA 5I2MA 4HATB 4PQ0A 1XR0B 3QIJA 1IRSA 3SO6A 2CRFA 3GYOA 2MFQA 1K5DB 4ZRIA 5DH9B 5LG4B 2DHJA 3QWMA 2K2JA 4CHJA 4A6HA 1DDWA 3ULBA 3CXBB 1P5TA 3ZDTA 2RLOA 1XD4A 1MIXA 4TKNA 2EJ8A 1Q67A 3DXDA 1T77A 2I5FA 1WJ1A 2GCJA 2OQBA 2DN6A 2K00A 3SYXA 2Z0QA 4WSFA 1UNQA 3A98B 5J3QA 5JLJB 1XODA 1AWEA 4K81A 4F7UP 1LW3A 1U27A 3ODWA 3WYFB 1WGQA 2CY5A 1V5MA 4KVGB 5D3YA 4QJ4B 2D10A 4HAUB 1SGHA 5HE2A 2DTCA 2CY4A 2MWNB 1ZC4B 1EAZA 5D3VA 2LKOA 2RRFA 3PP2A 1ZSQA 3OHMB 4HB3B 1SHCA 3ULCA 4EJNA 1KI1B 1UPRA 4KHBB 2VRWB 3BJIA 1XX0A 4H8SA 2M14A 1NTYA 2JP2A 2LULA 4GNKB 1X11A 1J0WA 3PEGA 4HB2B 2D11A 1QQGA 2I5CA 3ML4A 4GOUA 5C5BB 2NBVA 1X1GA 2HTHB 2GJYA 3KSYA 1ZYIA 3AU5A 2D9XA 4KHOA 2ELBA 3ODOA 2ROZB 1V61A 4GPTB 1ISNA 1BTNA 1U2BA 4Y94A 3B77A 1FB8A 2W2XD 2D4QA 2YS3A 2ZKMX 2DYNA 3MDBC 5CLQB 1ZC3B 1UPQA 2DHKA 3IVFA 2COCA 5DHFB 2ELAA 4TYZA 1J19A 2D2QA 2QKLA 2N0YA 4HB0B 3KY9A 3KZ1A 2UZSA 3O96A 1W1DA 2E2XA 1MKEA 2UZRA 2EC1A 3FEHA 1Y19B 2IYBA 4GZUA 2DFKA 1WI1A 1V89A 4A6KA 3PVLA 1E5WA 4WJ7A 5M4YB 1TQZA 4HDOA 3PG7A 3F5RA 1M7RA 2COAA 2K2UA 3P7ZA 5FI1A 3D8DA 2VKIA 2Z0OA 3D8FA 5HE3A 2GUMA 3U8ZA 5I2SA 1DDMA 1DBHA 4HAYB 5C16A 2ROVA 4DIXA 2RGNB 2YVCA 1NU2A 4K2OA 2L1CA 3AJ4A 3KRWA 4IFSA 2QKMA 4DX8A 2Z0PA 1NTVA 4YL8A 1PMSA 4EKUA 1MI1A 4XWXA 2LOZA 2MDXA 1GC7A 2RNRB 1UEFA 2M38A 2Y8GA 2DKPA 2DX1A 4PNKA 1EGXA 4CYEA 1DDVA 3FSSA 4HSIA 2D9VA 4DX90
chains in the Genus database with same CATH topology
5CLLB 2AEHA 3T06A 4A5KA 4K2PA 1U5GA 2KUPA 4MT7A 3RCPA 4MK0A 4F7GA 1XKEA 2J0JA 1BAKA 5DI9B 1TJ6A 4HB4B 1P6SA 4NY0A 4DBBA 3D8EA 3SV1A 1H10A 3MPXA 1FGYA 3NSUA 1PLSA 1V5UA 4ZRKA 2J59M 1MIZB 2I1KA 2I1JA 3A8PA 1MK7B 5J3TA 2DA0A 1XCGA 2DLWA 5D3XA 2KCJA 1KZ7A 5KCVA 2DHIA 5DHAB 2HE7A 1MAIA 2LOXA 2NZ8B 5HE0A 5HE1A 2ZPYA 1V5PA 2P8VA 2W2WA 1OMWA 5C79A 3BINA 4B6HA 1RRPB 5J3YA 1NI2A 1MK9B 2AL6A 3WA0A 1FHOA 2D9ZA 1DYNA 2Q13A 2YRYA 2J0KA 5C5BA 1TXDA 2H7DA 3PSCA 2MKRA 4HAZB 2RUKB 1RJ2A 3M1IB 1V88A 1I2HA 2YT1A 1K5GB 1OQNA 3G9WA 2P0FA 2YF0A 3HW2B 5JHHA 3N7CA 3TCAA 3OANA 3A8QA 1WJMA 3TFMA 1FHXA 2X18A 4GXBA 3V5WA 3TO1A 1N3HA 3GYPA 5D3WA 2L2IA 1DROA 5EFXA 5JP4A 1U29A 2RVBB 1U5FA 5LONB 1P3RA 5D27A 1PFJA 2ADZA 4EMOA 4GN1A 2CAYA 4WVFB 5C6RA 5GOWB 3PZDA 4GMVA 3VOQA 4P7IA 2YT0A 2OTXA 3U7DA 1WGUA 3VIAA 1GC6A 2D9WA 1H4RA 2YSZA 1X1FA 1EVHA 2D9YA 2R0DA 2Y8FA 4F7HA 4D0NB 3HK0A 2DKQA 3P6AA 4YONA 4HDQA 2YS5A 3LJUX 5KQ4A 4HAXB 3DXEA 1EF1A 2LG1A 2J0MA 4KHAA 1BTKA 1X05A 2FJLA 5KQ1A 1AQCA 2COFA 2EMSA 4HAWB 4DXAB 2DX5A 4CHMA 2GS0A 2V76A 2P0DA 2XQNM 4L6EA 3CIKA 1M7EA 5LOPB 1UNPA 1ZM0A 4C0AA 2H7EA 1FAOA 1MPHA 4IAPA 3X23A 2Y7BA 1W1GA 5FI0A 4Z2NA 2P0HA 3DXCA 3PVWA 5L81A 4A6FB 1FOEA 5DIFB 2PZ1A 2IFSA 1BWNA 1W1HA 1GG3A 1I7AA 2NMBA 1Y5OA 2CODA 4HAVB 4Z2MB 4BBKA 3SUZA 2VSZA 4K17A 3KRXA 1Z87A 1OY2A 1B55A 2BCJA 1QC6A 4A6FA 2N23A 1U5DA 3F0WA 4HHVA 4ZRJA 2W2XC 3HQCA 2UVMA 4GMXB 2G35A 2KGXB 2DYQA 2YS1A 3PVUA 3AU4A 1KZGA 4NSWA 2EMTA 1X86A 2R09A 4KAXB 1FHWA 1WG7A 1FGZA 1ZVRA 2GCLA 3FM8C 4IOYX 3ZVRA 5JHGA 1WVHA 4MY6A 2LYDA 1U5EA 3ODXA 3SNHA 3QBVB 3TW1A 1UNRA 1LB1A 3TVVA 3UZTA 2RSGA 4HATB 4PQ0A 1XR0B 3QIJA 1IRSA 3SO6A 2CRFA 3GYOA 2MFQA 1K5DB 4ZRIA 5DH9B 2DHJA 3QWMA 2K2JA 4CHJA 4A6HA 1DDWA 3ULBA 3CXBB 1P5TA 3ZDTA 2RLOA 1XD4A 1MIXA 4TKNA 2EJ8A 1Q67A 3DXDA 2I5FA 1WJ1A 2GCJA 2OQBA 2DN6A 2K00A 3SYXA 2Z0QA 4WSFA 1UNQA 3A98B 5J3QA 5JLJB 1XODA 1AWEA 4K81A 4F7UP 1LW3A 1U27A 3ODWA 3WYFB 1WGQA 2CY5A 1V5MA 4KVGB 5D3YA 2D10A 4HAUB 1SGHA 5HE2A 2DTCA 2CY4A 2MWNB 1ZC4B 1EAZA 5D3VA 2LKOA 3PP2A 1ZSQA 4HB3B 1SHCA 3ULCA 4EJNA 1KI1B 1UPRA 4KHBB 2VRWB 3BJIA 1XX0A 4H8SA 2M14A 1NTYA 2JP2A 2LULA 1X11A 1J0WA 3PEGA 4HB2B 2D11A 1QQGA 2I5CA 3ML4A 5C5BB 1X1GA 2HTHB 2GJYA 3KSYA 3AU5A 2D9XA 4KHOA 2ELBA 3ODOA 2ROZB 1V61A 4GPTB 1ISNA 1BTNA 1U2BA 4Y94A 1FB8A 2W2XD 2D4QA 2YS3A 2DYNA 3MDBC 5CLQB 1ZC3B 1UPQA 2DHKA 3IVFA 2COCA 5DHFB 2ELAA 4TYZA 1J19A 2D2QA 2QKLA 2N0YA 4HB0B 3KY9A 3KZ1A 2UZSA 3O96A 1W1DA 2E2XA 1MKEA 2UZRA 2EC1A 3FEHA 1Y19B 2IYBA 4GZUA 2DFKA 1WI1A 1V89A 4A6KA 3PVLA 1E5WA 4WJ7A 1TQZA 4HDOA 3PG7A 3F5RA 1M7RA 2COAA 2K2UA 3P7ZA 5FI1A 3D8DA 2VKIA 2Z0OA 3D8FA 5HE3A 3U8ZA 1DDMA 1DBHA 4HAYB 5C16A 2ROVA 2RGNB 2YVCA 1NU2A 4K2OA 2L1CA 3AJ4A 3KRWA 4IFSA 2QKMA 4DX8A 2Z0PA 1NTVA 4YL8A 1PMSA 4EKUA 4XWXA 2LOZA 2MDXA 1GC7A 2RNRB 1UEFA 2M38A 2Y8GA 2DKPA 2DX1A 4PNKA 1EGXA 4CYEA 1DDVA 3FSSA 2D9VA 4DX90
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CLL B;  2AEH A;  3T06 A;  4A5K A;  4K2P A;  1U5G A;  2KUP A;  4MT7 A;  3RCP A;  4MK0 A;  4F7G A;  1XKE A;  2J0J A;  1BAK A;  5DI9 B;  1TJ6 A;  4HB4 B;  1P6S A;  4NY0 A;  4DBB A;  3D8E A;  3SV1 A;  1H10 A;  3MPX A;  1FGY A;  3NSU A;  1PLS A;  1V5U A;  4ZRK A;  2J59 M;  1MIZ B;  2I1K A;  2I1J A;  3A8P A;  1MK7 B;  5J3T A;  2DA0 A;  1XCG A;  2DLW A;  5D3X A;  2KCJ A;  1KZ7 A;  5KCV A;  2DHI A;  5DHA B;  2HE7 A;  1MAI A;  2LOX A;  2NZ8 B;  5HE0 A;  5HE1 A;  2ZPY A;  1V5P A;  2P8V A;  2W2W A;  1OMW A;  5C79 A;  3BIN A;  4B6H A;  1RRP B;  5J3Y A;  1NI2 A;  1MK9 B;  2AL6 A;  3WA0 A;  1FHO A;  2D9Z A;  1DYN A;  2Q13 A;  2YRY A;  2J0K A;  5C5B A;  1TXD A;  2H7D A;  3PSC A;  2MKR A;  4HAZ B;  2RUK B;  1RJ2 A;  3M1I B;  1V88 A;  1I2H A;  2YT1 A;  1K5G B;  1OQN A;  3G9W A;  2P0F A;  2YF0 A;  3HW2 B;  5JHH A;  3N7C A;  3TCA A;  3OAN A;  3A8Q A;  1WJM A;  3TFM A;  1FHX A;  2X18 A;  4GXB A;  3V5W A;  3TO1 A;  1N3H A;  3GYP A;  5D3W A;  2L2I A;  1DRO A;  5EFX A;  5JP4 A;  1U29 A;  2RVB B;  1U5F A;  5LON B;  1P3R A;  5D27 A;  1PFJ A;  2ADZ A;  4EMO A;  4GN1 A;  2CAY A;  4WVF B;  5C6R A;  5GOW B;  3PZD A;  4GMV A;  3VOQ A;  4P7I A;  2YT0 A;  2OTX A;  3U7D A;  1WGU A;  3VIA A;  1GC6 A;  2D9W A;  1H4R A;  2YSZ A;  1X1F A;  1EVH A;  2D9Y A;  2R0D A;  2Y8F A;  4F7H A;  4D0N B;  3HK0 A;  2DKQ A;  3P6A A;  4YON A;  4HDQ A;  2YS5 A;  3LJU X;  5KQ4 A;  4HAX B;  3DXE A;  1EF1 A;  2LG1 A;  2J0M A;  4KHA A;  1BTK A;  1X05 A;  2FJL A;  5KQ1 A;  1AQC A;  2COF A;  2EMS A;  4HAW B;  4DXA B;  2DX5 A;  4CHM A;  2GS0 A;  2V76 A;  2P0D A;  2XQN M;  4L6E A;  3CIK A;  1M7E A;  5LOP B;  1UNP A;  1ZM0 A;  4C0A A;  2H7E A;  1FAO A;  1MPH A;  4IAP A;  3X23 A;  2Y7B A;  1W1G A;  5FI0 A;  4Z2N A;  2P0H A;  3DXC A;  3PVW A;  5L81 A;  4A6F B;  1FOE A;  5DIF B;  2PZ1 A;  2IFS A;  1BWN A;  1W1H A;  1GG3 A;  1I7A A;  2NMB A;  1Y5O A;  2COD A;  4HAV B;  4Z2M B;  4BBK A;  3SUZ A;  2VSZ A;  4K17 A;  3KRX A;  1Z87 A;  1OY2 A;  1B55 A;  2BCJ A;  1QC6 A;  4A6F A;  2N23 A;  1U5D A;  3F0W A;  4HHV A;  4ZRJ A;  2W2X C;  3HQC A;  2UVM A;  4GMX B;  2G35 A;  2KGX B;  2DYQ A;  2YS1 A;  3PVU A;  3AU4 A;  1KZG A;  4NSW A;  2EMT A;  1X86 A;  2R09 A;  4KAX B;  1FHW A;  1WG7 A;  1FGZ A;  1ZVR A;  2GCL A;  3FM8 C;  4IOY X;  3ZVR A;  5JHG A;  1WVH A;  4MY6 A;  2LYD A;  1U5E A;  3ODX A;  3SNH A;  3QBV B;  3TW1 A;  1UNR A;  1LB1 A;  3TVV A;  3UZT A;  2RSG A;  4HAT B;  4PQ0 A;  1XR0 B;  3QIJ A;  1IRS A;  3SO6 A;  2CRF A;  3GYO A;  2MFQ A;  1K5D B;  4ZRI A;  5DH9 B;  2DHJ A;  3QWM A;  2K2J A;  4CHJ A;  4A6H A;  1DDW A;  3ULB A;  3CXB B;  1P5T A;  3ZDT A;  2RLO A;  1XD4 A;  1MIX A;  4TKN A;  2EJ8 A;  1Q67 A;  3DXD A;  2I5F A;  1WJ1 A;  2GCJ A;  2OQB A;  2DN6 A;  2K00 A;  3SYX A;  2Z0Q A;  4WSF A;  1UNQ A;  3A98 B;  5J3Q A;  5JLJ B;  1XOD A;  1AWE A;  4K81 A;  4F7U P;  1LW3 A;  1U27 A;  3ODW A;  3WYF B;  1WGQ A;  2CY5 A;  1V5M A;  4KVG B;  5D3Y A;  2D10 A;  4HAU B;  1SGH A;  5HE2 A;  2DTC A;  2CY4 A;  2MWN B;  1ZC4 B;  1EAZ A;  5D3V A;  2LKO A;  3PP2 A;  1ZSQ A;  4HB3 B;  1SHC A;  3ULC A;  4EJN A;  1KI1 B;  1UPR A;  4KHB B;  2VRW B;  3BJI A;  1XX0 A;  4H8S A;  2M14 A;  1NTY A;  2JP2 A;  2LUL A;  1X11 A;  1J0W A;  3PEG A;  4HB2 B;  2D11 A;  1QQG A;  2I5C A;  3ML4 A;  5C5B B;  1X1G A;  2HTH B;  2GJY A;  3KSY A;  3AU5 A;  2D9X A;  4KHO A;  2ELB A;  3ODO A;  2ROZ B;  1V61 A;  4GPT B;  1ISN A;  1BTN A;  1U2B A;  4Y94 A;  1FB8 A;  2W2X D;  2D4Q A;  2YS3 A;  2DYN A;  3MDB C;  5CLQ B;  1ZC3 B;  1UPQ A;  2DHK A;  3IVF A;  2COC A;  5DHF B;  2ELA A;  4TYZ A;  1J19 A;  2D2Q A;  2QKL A;  2N0Y A;  4HB0 B;  3KY9 A;  3KZ1 A;  2UZS A;  3O96 A;  1W1D A;  2E2X A;  1MKE A;  2UZR A;  2EC1 A;  3FEH A;  1Y19 B;  2IYB A;  4GZU A;  2DFK A;  1WI1 A;  1V89 A;  4A6K A;  3PVL A;  1E5W A;  4WJ7 A;  1TQZ A;  4HDO A;  3PG7 A;  3F5R A;  1M7R A;  2COA A;  2K2U A;  3P7Z A;  5FI1 A;  3D8D A;  2VKI A;  2Z0O A;  3D8F A;  5HE3 A;  3U8Z A;  1DDM A;  1DBH A;  4HAY B;  5C16 A;  2ROV A;  2RGN B;  2YVC A;  1NU2 A;  4K2O A;  2L1C A;  3AJ4 A;  3KRW A;  4IFS A;  2QKM A;  4DX8 A;  2Z0P A;  1NTV A;  4YL8 A;  1PMS A;  4EKU A;  4XWX A;  2LOZ A;  2MDX A;  1GC7 A;  2RNR B;  1UEF A;  2M38 A;  2Y8G A;  2DKP A;  2DX1 A;  4PNK A;  1EGX A;  4CYE A;  1DDV A;  3FSS A;  2D9V A;  4DX9 0; 
#chains in the Genus database with same CATH topology
 5CLL B;  2AEH A;  3T06 A;  4A5K A;  4K2P A;  1U5G A;  2KUP A;  4MT7 A;  3RCP A;  4MK0 A;  4F7G A;  1XKE A;  2J0J A;  4OSN A;  3NWD A;  1BAK A;  5DI9 B;  1TJ6 A;  4HB4 B;  1P6S A;  4NY0 A;  4DBB A;  3D8E A;  3SV1 A;  1H10 A;  2Z59 A;  3MPX A;  1FGY A;  3NSU A;  1PLS A;  1V5U A;  4ZRK A;  2J59 M;  1MIZ B;  2I1K A;  2I1J A;  3A8P A;  1MK7 B;  5J3T A;  2DA0 A;  1XCG A;  2DLW A;  5D3X A;  2KCJ A;  1KZ7 A;  5KCV A;  2DHI A;  5DHA B;  2HE7 A;  1MAI A;  2LOX A;  2NZ8 B;  5HE0 A;  5HE1 A;  2ZPY A;  1V5P A;  2P8V A;  2W2W A;  1OMW A;  5C79 A;  3BIN A;  4B6H A;  4KHB A;  1RRP B;  5J3Y A;  1NI2 A;  3FVC A;  1MK9 B;  2AL6 A;  3WA0 A;  2FJU B;  1FHO A;  2D9Z A;  1DYN A;  2Q13 A;  2YRY A;  4QJ3 B;  2J0K A;  5C5B A;  1TXD A;  2H7D A;  3NWF A;  3PSC A;  2MKR A;  3HSA A;  4HAZ B;  2RUK B;  1RJ2 A;  3M1I B;  1V88 A;  1I2H A;  2YT1 A;  1K5G B;  1OQN A;  2YT2 A;  3G9W A;  2P0F A;  2YF0 A;  3HW2 B;  5JHH A;  3N7C A;  3TCA A;  3OAN A;  3A8Q A;  1WJM A;  3TFM A;  1FHX A;  2X18 A;  4GXB A;  3V5W A;  3TO1 A;  1N3H A;  4CSQ A;  3GYP A;  2Z14 A;  5D3W A;  2L2I A;  1DRO A;  5EFX A;  5JP4 A;  1U29 A;  2KIE A;  2RVB B;  1U5F A;  5LON B;  3HIE A;  1P3R A;  5D27 A;  1PFJ A;  2ADZ A;  4EMO A;  4GN1 A;  2CAY A;  3NWA A;  4WVF B;  5C6R A;  5GOW B;  3PZD A;  4GMV A;  3VOQ A;  4P7I A;  2YT0 A;  3A58 A;  2OTX A;  4QXA B;  3U7D A;  1WGU A;  3VIA A;  1GC6 A;  2D9W A;  1H4R A;  2YSZ A;  1X1F A;  1EVH A;  2D9Y A;  2K49 A;  2R0D A;  2Y8F A;  4F7H A;  4D0N B;  3U12 A;  2Z4D A;  3HK0 A;  2DKQ A;  3P6A A;  4YON A;  4HDQ A;  2YS5 A;  3LJU X;  5KQ4 A;  4D6W A;  4HAX B;  3DXE A;  1EF1 A;  3NW8 A;  2LG1 A;  2J0M A;  4KHA A;  4OT1 A;  1BTK A;  1X05 A;  2FJL A;  5KQ1 A;  1AQC A;  2COF A;  2EMS A;  4HAW B;  4DXA B;  2DX5 A;  2KR0 A;  4CHM A;  2GS0 A;  2V76 A;  2P0D A;  2KIG A;  2XQN M;  4L6E A;  3CIK A;  1M7E A;  5LOP B;  1UNP A;  1ZM0 A;  4C0A A;  2H7E A;  1FAO A;  1MPH A;  4IAP A;  3X23 A;  2Y7B A;  1W1G A;  5FI0 A;  4Z2N A;  2P0H A;  3DXC A;  3PVW A;  5L81 A;  4A6F B;  1FOE A;  5DIF B;  2PZ1 A;  2IFS A;  2K8E A;  1BWN A;  1W1H A;  1GG3 A;  1I7A A;  2NMB A;  1Y5O A;  2COD A;  4HAV B;  4QJ5 B;  4Z2M B;  4BBK A;  3SUZ A;  2VSZ A;  4K17 A;  3KRX A;  1Z87 A;  1OY2 A;  1B55 A;  2BCJ A;  1QC6 A;  4A6F A;  5IRS A;  2N23 A;  1U5D A;  4L1R A;  3F0W A;  4HHV A;  4ZRJ A;  2W2X C;  3HQC A;  2UVM A;  4GMX B;  2G35 A;  2KGX B;  2DYQ A;  2YS1 A;  3PVU A;  3AU4 A;  1KZG A;  4NSW A;  3DCX A;  2EMT A;  2R2Y A;  1X86 A;  2KUQ A;  2R09 A;  4KAX B;  1FHW A;  1WG7 A;  1FGZ A;  1ZVR A;  2GCL A;  3FM8 C;  4IOY X;  3ZVR A;  5JHG A;  1WVH A;  4MY6 A;  2LYD A;  1U5E A;  2Z13 A;  3ODX A;  3SNH A;  3QBV B;  3TW1 A;  1UNR A;  1LB1 A;  3TVV A;  3UZT A;  2RSG A;  5I2M A;  4HAT B;  4PQ0 A;  1XR0 B;  3QIJ A;  1IRS A;  3SO6 A;  2CRF A;  3GYO A;  2MFQ A;  1K5D B;  4ZRI A;  5DH9 B;  5LG4 B;  2DHJ A;  3QWM A;  2K2J A;  4CHJ A;  4A6H A;  1DDW A;  3ULB A;  3CXB B;  1P5T A;  3ZDT A;  2RLO A;  1XD4 A;  1MIX A;  4TKN A;  2EJ8 A;  1Q67 A;  3DXD A;  1T77 A;  2I5F A;  1WJ1 A;  2GCJ A;  2OQB A;  2DN6 A;  2K00 A;  3SYX A;  2Z0Q A;  4WSF A;  1UNQ A;  3A98 B;  5J3Q A;  5JLJ B;  1XOD A;  1AWE A;  4K81 A;  4F7U P;  1LW3 A;  1U27 A;  3ODW A;  3WYF B;  1WGQ A;  2CY5 A;  1V5M A;  4KVG B;  5D3Y A;  4QJ4 B;  2D10 A;  4HAU B;  1SGH A;  5HE2 A;  2DTC A;  2CY4 A;  2MWN B;  1ZC4 B;  1EAZ A;  5D3V A;  2LKO A;  2RRF A;  3PP2 A;  1ZSQ A;  3OHM B;  4HB3 B;  1SHC A;  3ULC A;  4EJN A;  1KI1 B;  1UPR A;  4KHB B;  2VRW B;  3BJI A;  1XX0 A;  4H8S A;  2M14 A;  1NTY A;  2JP2 A;  2LUL A;  4GNK B;  1X11 A;  1J0W A;  3PEG A;  4HB2 B;  2D11 A;  1QQG A;  2I5C A;  3ML4 A;  4GOU A;  5C5B B;  2NBV A;  1X1G A;  2HTH B;  2GJY A;  3KSY A;  1ZYI A;  3AU5 A;  2D9X A;  4KHO A;  2ELB A;  3ODO A;  2ROZ B;  1V61 A;  4GPT B;  1ISN A;  1BTN A;  1U2B A;  4Y94 A;  3B77 A;  1FB8 A;  2W2X D;  2D4Q A;  2YS3 A;  2ZKM X;  2DYN A;  3MDB C;  5CLQ B;  1ZC3 B;  1UPQ A;  2DHK A;  3IVF A;  2COC A;  5DHF B;  2ELA A;  4TYZ A;  1J19 A;  2D2Q A;  2QKL A;  2N0Y A;  4HB0 B;  3KY9 A;  3KZ1 A;  2UZS A;  3O96 A;  1W1D A;  2E2X A;  1MKE A;  2UZR A;  2EC1 A;  3FEH A;  1Y19 B;  2IYB A;  4GZU A;  2DFK A;  1WI1 A;  1V89 A;  4A6K A;  3PVL A;  1E5W A;  4WJ7 A;  5M4Y B;  1TQZ A;  4HDO A;  3PG7 A;  3F5R A;  1M7R A;  2COA A;  2K2U A;  3P7Z A;  5FI1 A;  3D8D A;  2VKI A;  2Z0O A;  3D8F A;  5HE3 A;  2GUM A;  3U8Z A;  5I2S A;  1DDM A;  1DBH A;  4HAY B;  5C16 A;  2ROV A;  4DIX A;  2RGN B;  2YVC A;  1NU2 A;  4K2O A;  2L1C A;  3AJ4 A;  3KRW A;  4IFS A;  2QKM A;  4DX8 A;  2Z0P A;  1NTV A;  4YL8 A;  1PMS A;  4EKU A;  1MI1 A;  4XWX A;  2LOZ A;  2MDX A;  1GC7 A;  2RNR B;  1UEF A;  2M38 A;  2Y8G A;  2DKP A;  2DX1 A;  4PNK A;  1EGX A;  4CYE A;  1DDV A;  3FSS A;  4HSI A;  2D9V A;  4DX9 0; 
#chains in the Genus database with same CATH homology
 5CLL B;  2AEH A;  3T06 A;  4A5K A;  4K2P A;  1U5G A;  2KUP A;  4MT7 A;  3RCP A;  4MK0 A;  4F7G A;  1XKE A;  2J0J A;  1BAK A;  5DI9 B;  1TJ6 A;  4HB4 B;  1P6S A;  4NY0 A;  4DBB A;  3D8E A;  3SV1 A;  1H10 A;  3MPX A;  1FGY A;  3NSU A;  1PLS A;  1V5U A;  4ZRK A;  2J59 M;  1MIZ B;  2I1K A;  2I1J A;  3A8P A;  1MK7 B;  5J3T A;  2DA0 A;  1XCG A;  2DLW A;  5D3X A;  2KCJ A;  1KZ7 A;  5KCV A;  2DHI A;  5DHA B;  2HE7 A;  1MAI A;  2LOX A;  2NZ8 B;  5HE0 A;  5HE1 A;  2ZPY A;  1V5P A;  2P8V A;  2W2W A;  1OMW A;  5C79 A;  3BIN A;  4B6H A;  1RRP B;  5J3Y A;  1NI2 A;  1MK9 B;  2AL6 A;  3WA0 A;  1FHO A;  2D9Z A;  1DYN A;  2Q13 A;  2YRY A;  2J0K A;  5C5B A;  1TXD A;  2H7D A;  3PSC A;  2MKR A;  4HAZ B;  2RUK B;  1RJ2 A;  3M1I B;  1V88 A;  1I2H A;  2YT1 A;  1K5G B;  1OQN A;  3G9W A;  2P0F A;  2YF0 A;  3HW2 B;  5JHH A;  3N7C A;  3TCA A;  3OAN A;  3A8Q A;  1WJM A;  3TFM A;  1FHX A;  2X18 A;  4GXB A;  3V5W A;  3TO1 A;  1N3H A;  3GYP A;  5D3W A;  2L2I A;  1DRO A;  5EFX A;  5JP4 A;  1U29 A;  2RVB B;  1U5F A;  5LON B;  1P3R A;  5D27 A;  1PFJ A;  2ADZ A;  4EMO A;  4GN1 A;  2CAY A;  4WVF B;  5C6R A;  5GOW B;  3PZD A;  4GMV A;  3VOQ A;  4P7I A;  2YT0 A;  2OTX A;  3U7D A;  1WGU A;  3VIA A;  1GC6 A;  2D9W A;  1H4R A;  2YSZ A;  1X1F A;  1EVH A;  2D9Y A;  2R0D A;  2Y8F A;  4F7H A;  4D0N B;  3HK0 A;  2DKQ A;  3P6A A;  4YON A;  4HDQ A;  2YS5 A;  3LJU X;  5KQ4 A;  4HAX B;  3DXE A;  1EF1 A;  2LG1 A;  2J0M A;  4KHA A;  1BTK A;  1X05 A;  2FJL A;  5KQ1 A;  1AQC A;  2COF A;  2EMS A;  4HAW B;  4DXA B;  2DX5 A;  4CHM A;  2GS0 A;  2V76 A;  2P0D A;  2XQN M;  4L6E A;  3CIK A;  1M7E A;  5LOP B;  1UNP A;  1ZM0 A;  4C0A A;  2H7E A;  1FAO A;  1MPH A;  4IAP A;  3X23 A;  2Y7B A;  1W1G A;  5FI0 A;  4Z2N A;  2P0H A;  3DXC A;  3PVW A;  5L81 A;  4A6F B;  1FOE A;  5DIF B;  2PZ1 A;  2IFS A;  1BWN A;  1W1H A;  1GG3 A;  1I7A A;  2NMB A;  1Y5O A;  2COD A;  4HAV B;  4Z2M B;  4BBK A;  3SUZ A;  2VSZ A;  4K17 A;  3KRX A;  1Z87 A;  1OY2 A;  1B55 A;  2BCJ A;  1QC6 A;  4A6F A;  2N23 A;  1U5D A;  3F0W A;  4HHV A;  4ZRJ A;  2W2X C;  3HQC A;  2UVM A;  4GMX B;  2G35 A;  2KGX B;  2DYQ A;  2YS1 A;  3PVU A;  3AU4 A;  1KZG A;  4NSW A;  2EMT A;  1X86 A;  2R09 A;  4KAX B;  1FHW A;  1WG7 A;  1FGZ A;  1ZVR A;  2GCL A;  3FM8 C;  4IOY X;  3ZVR A;  5JHG A;  1WVH A;  4MY6 A;  2LYD A;  1U5E A;  3ODX A;  3SNH A;  3QBV B;  3TW1 A;  1UNR A;  1LB1 A;  3TVV A;  3UZT A;  2RSG A;  4HAT B;  4PQ0 A;  1XR0 B;  3QIJ A;  1IRS A;  3SO6 A;  2CRF A;  3GYO A;  2MFQ A;  1K5D B;  4ZRI A;  5DH9 B;  2DHJ A;  3QWM A;  2K2J A;  4CHJ A;  4A6H A;  1DDW A;  3ULB A;  3CXB B;  1P5T A;  3ZDT A;  2RLO A;  1XD4 A;  1MIX A;  4TKN A;  2EJ8 A;  1Q67 A;  3DXD A;  2I5F A;  1WJ1 A;  2GCJ A;  2OQB A;  2DN6 A;  2K00 A;  3SYX A;  2Z0Q A;  4WSF A;  1UNQ A;  3A98 B;  5J3Q A;  5JLJ B;  1XOD A;  1AWE A;  4K81 A;  4F7U P;  1LW3 A;  1U27 A;  3ODW A;  3WYF B;  1WGQ A;  2CY5 A;  1V5M A;  4KVG B;  5D3Y A;  2D10 A;  4HAU B;  1SGH A;  5HE2 A;  2DTC A;  2CY4 A;  2MWN B;  1ZC4 B;  1EAZ A;  5D3V A;  2LKO A;  3PP2 A;  1ZSQ A;  4HB3 B;  1SHC A;  3ULC A;  4EJN A;  1KI1 B;  1UPR A;  4KHB B;  2VRW B;  3BJI A;  1XX0 A;  4H8S A;  2M14 A;  1NTY A;  2JP2 A;  2LUL A;  1X11 A;  1J0W A;  3PEG A;  4HB2 B;  2D11 A;  1QQG A;  2I5C A;  3ML4 A;  5C5B B;  1X1G A;  2HTH B;  2GJY A;  3KSY A;  3AU5 A;  2D9X A;  4KHO A;  2ELB A;  3ODO A;  2ROZ B;  1V61 A;  4GPT B;  1ISN A;  1BTN A;  1U2B A;  4Y94 A;  1FB8 A;  2W2X D;  2D4Q A;  2YS3 A;  2DYN A;  3MDB C;  5CLQ B;  1ZC3 B;  1UPQ A;  2DHK A;  3IVF A;  2COC A;  5DHF B;  2ELA A;  4TYZ A;  1J19 A;  2D2Q A;  2QKL A;  2N0Y A;  4HB0 B;  3KY9 A;  3KZ1 A;  2UZS A;  3O96 A;  1W1D A;  2E2X A;  1MKE A;  2UZR A;  2EC1 A;  3FEH A;  1Y19 B;  2IYB A;  4GZU A;  2DFK A;  1WI1 A;  1V89 A;  4A6K A;  3PVL A;  1E5W A;  4WJ7 A;  1TQZ A;  4HDO A;  3PG7 A;  3F5R A;  1M7R A;  2COA A;  2K2U A;  3P7Z A;  5FI1 A;  3D8D A;  2VKI A;  2Z0O A;  3D8F A;  5HE3 A;  3U8Z A;  1DDM A;  1DBH A;  4HAY B;  5C16 A;  2ROV A;  2RGN B;  2YVC A;  1NU2 A;  4K2O A;  2L1C A;  3AJ4 A;  3KRW A;  4IFS A;  2QKM A;  4DX8 A;  2Z0P A;  1NTV A;  4YL8 A;  1PMS A;  4EKU A;  4XWX A;  2LOZ A;  2MDX A;  1GC7 A;  2RNR B;  1UEF A;  2M38 A;  2Y8G A;  2DKP A;  2DX1 A;  4PNK A;  1EGX A;  4CYE A;  1DDV A;  3FSS A;  2D9V A;  4DX9 0; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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