2NTIC

Crystal structure of pcna123 heterotrimer.
Total Genus 61
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
244
structure length
244
Chain Sequence
MKVVYDDVRVLKDIIQALARLVDEAVLKFKQDSVELVALDRAHISLISVNLPREMFKEYDVNDEFKFGFNTQYLMKILKVAKRKEAIEIASESPDSVIINIIGSTNREFNVRNLEVSEQEIPEINLQFDISATISSDGFKSAISEVSTVTDNVVVEGHEDRILIKAEGESEVEVEFSKDTGGLQDLEFSKESKNSYSAEYLDDVLSLTKLSDYVKISFGNQKPLQLFFNMEGGGKVTYLLAPKV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Sulfolobus solfataricus
molecule keywords DNA polymerase sliding clamp B
total genus 61
structure length 244
sequence length 244
chains with identical sequence F, I
ec nomenclature
pdb deposition date 2006-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
C PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2ntiC00
3A1JA 5H0TA 4D2GA 4CS5A 5E0UA 2OD8A 3A2FB 4RJFA 3G65C 3P83A 4L6PA 1PLRA 1YYPA 2HIKB 5AUJA 3GPNA 2IZOB 2HIKA 1IZ4A 3U61F 1W60A 3LX1A 2ZVKA 1VYJA 3A1JB 3WGWA 3LX2A 5E0VA 2HIIC 2AVTA 2ZVLA 5IWDA 3U60F 4ZTDA 5DA7A 1SXJF 3P91A 1U7BA 4YHRA 1B77A 3GGRC 5DAIA 3AIXA 3U5ZF 1RWZA 3HI8A 2IO4B 3G65A 3F1WA 5CFKA 1UL1A 1AXCA 2IX2C 3AIZC 2NTIC 5IY4A 2IO4A 5B7OA 1IZ5A 2ZVVA 1B8HA 3FDSC 2Z0LA 3I2MX 5JNED 3A1JC 3GPMA 3AIXB 1UD9A 5HACA 3V62B 3AIZA 4TR6A 3HSLX 1PLQA 1RXZA 2ZVWA 3G65B 2HIIA 1RXMA 1CZDA 2HIKC 1GE8A 5E0TA 3V61B 4L60A 2IZOC 3P87A 3GGRA 2IJXA 3FDSD 3VKXA 4HK1A 1T6LA 1ISQA 2IX2B 2NTIB 5A6DA 2HIIB 3V60B 2IX2A 2NTIA 1DMLA 3IFVA 1VYMA 1U76A 5IXAA 3K4XA 3TBLA 2ZVMA 2AWAA 3GGRB
chains in the Genus database with same CATH superfamily
3A1JA 5H0TA 4D2GA 4CS5A 5E0UA 2OD8A 3A2FB 4RJFA 3G65C 3P83A 4L6PA 1PLRA 1YYPA 2HIKB 5AUJA 3GPNA 2IZOB 2HIKA 1IZ4A 3U61F 1W60A 3LX1A 2ZVKA 1VYJA 3A1JB 3WGWA 3LX2A 5E0VA 2HIIC 2AVTA 2ZVLA 5IWDA 3U60F 4ZTDA 5DA7A 1SXJF 3P91A 1U7BA 4YHRA 1B77A 3GGRC 5DAIA 3AIXA 3U5ZF 1RWZA 3HI8A 2IO4B 3G65A 3F1WA 5CFKA 1UL1A 1AXCA 2IX2C 3AIZC 2NTIC 5IY4A 2IO4A 5B7OA 1IZ5A 2ZVVA 1B8HA 3FDSC 2Z0LA 3I2MX 5JNED 3A1JC 3GPMA 3AIXB 1UD9A 5HACA 3V62B 3AIZA 4TR6A 3HSLX 1PLQA 1RXZA 2ZVWA 3G65B 2HIIA 1RXMA 1CZDA 2HIKC 1GE8A 5E0TA 3V61B 4L60A 2IZOC 3P87A 3GGRA 2IJXA 3FDSD 3VKXA 4HK1A 1T6LA 1ISQA 2IX2B 2NTIB 5A6DA 2HIIB 3V60B 2IX2A 2NTIA 1DMLA 3IFVA 1VYMA 1U76A 5IXAA 3K4XA 3TBLA 2ZVMA 2AWAA 3GGRB
chains in the Genus database with same CATH topology
3A1JA 5H0TA 4D2GA 4CS5A 5E0UA 2OD8A 3A2FB 4RJFA 3G65C 3P83A 4L6PA 1PLRA 1YYPA 2HIKB 5AUJA 3GPNA 2IZOB 2HIKA 1IZ4A 3U61F 1W60A 3LX1A 2ZVKA 1VYJA 3A1JB 3WGWA 3LX2A 5E0VA 2HIIC 2AVTA 2ZVLA 5IWDA 3U60F 4ZTDA 5DA7A 1SXJF 3P91A 1U7BA 4YHRA 1B77A 3GGRC 5DAIA 3AIXA 3U5ZF 1RWZA 3HI8A 2IO4B 3G65A 3F1WA 5CFKA 1UL1A 1AXCA 2IX2C 3AIZC 2NTIC 5IY4A 2IO4A 5B7OA 1IZ5A 2ZVVA 1B8HA 3FDSC 2Z0LA 3I2MX 5JNED 3A1JC 3GPMA 3AIXB 1UD9A 5HACA 3V62B 3AIZA 4TR6A 3HSLX 1PLQA 1RXZA 2ZVWA 3G65B 2HIIA 1RXMA 1CZDA 2HIKC 1GE8A 5E0TA 3V61B 4L60A 2IZOC 3P87A 3GGRA 2IJXA 3FDSD 3VKXA 4HK1A 1T6LA 1ISQA 2IX2B 2NTIB 5A6DA 2HIIB 3V60B 2IX2A 2NTIA 1DMLA 3IFVA 1VYMA 1U76A 5IXAA 3K4XA 3TBLA 2ZVMA 2AWAA 3GGRB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3A1J A;  5H0T A;  4D2G A;  4CS5 A;  5E0U A;  2OD8 A;  3A2F B;  4RJF A;  3G65 C;  3P83 A;  4L6P A;  1PLR A;  1YYP A;  2HIK B;  5AUJ A;  3GPN A;  2IZO B;  2HIK A;  1IZ4 A;  3U61 F;  1W60 A;  3LX1 A;  2ZVK A;  1VYJ A;  3A1J B;  3WGW A;  3LX2 A;  5E0V A;  2HII C;  2AVT A;  2ZVL A;  5IWD A;  3U60 F;  4ZTD A;  5DA7 A;  1SXJ F;  3P91 A;  1U7B A;  4YHR A;  1B77 A;  3GGR C;  5DAI A;  3AIX A;  3U5Z F;  1RWZ A;  3HI8 A;  2IO4 B;  3G65 A;  3F1W A;  5CFK A;  1UL1 A;  1AXC A;  2IX2 C;  3AIZ C;  2NTI C;  5IY4 A;  2IO4 A;  5B7O A;  1IZ5 A;  2ZVV A;  1B8H A;  3FDS C;  2Z0L A;  3I2M X;  5JNE D;  3A1J C;  3GPM A;  3AIX B;  1UD9 A;  5HAC A;  3V62 B;  3AIZ A;  4TR6 A;  3HSL X;  1PLQ A;  1RXZ A;  2ZVW A;  3G65 B;  2HII A;  1RXM A;  1CZD A;  2HIK C;  1GE8 A;  5E0T A;  3V61 B;  4L60 A;  2IZO C;  3P87 A;  3GGR A;  2IJX A;  3FDS D;  3VKX A;  4HK1 A;  1T6L A;  1ISQ A;  2IX2 B;  2NTI B;  5A6D A;  2HII B;  3V60 B;  2IX2 A;  2NTI A;  1DML A;  3IFV A;  1VYM A;  1U76 A;  5IXA A;  3K4X A;  3TBL A;  2ZVM A;  2AWA A;  3GGR B; 
#chains in the Genus database with same CATH topology
 3A1J A;  5H0T A;  4D2G A;  4CS5 A;  5E0U A;  2OD8 A;  3A2F B;  4RJF A;  3G65 C;  3P83 A;  4L6P A;  1PLR A;  1YYP A;  2HIK B;  5AUJ A;  3GPN A;  2IZO B;  2HIK A;  1IZ4 A;  3U61 F;  1W60 A;  3LX1 A;  2ZVK A;  1VYJ A;  3A1J B;  3WGW A;  3LX2 A;  5E0V A;  2HII C;  2AVT A;  2ZVL A;  5IWD A;  3U60 F;  4ZTD A;  5DA7 A;  1SXJ F;  3P91 A;  1U7B A;  4YHR A;  1B77 A;  3GGR C;  5DAI A;  3AIX A;  3U5Z F;  1RWZ A;  3HI8 A;  2IO4 B;  3G65 A;  3F1W A;  5CFK A;  1UL1 A;  1AXC A;  2IX2 C;  3AIZ C;  2NTI C;  5IY4 A;  2IO4 A;  5B7O A;  1IZ5 A;  2ZVV A;  1B8H A;  3FDS C;  2Z0L A;  3I2M X;  5JNE D;  3A1J C;  3GPM A;  3AIX B;  1UD9 A;  5HAC A;  3V62 B;  3AIZ A;  4TR6 A;  3HSL X;  1PLQ A;  1RXZ A;  2ZVW A;  3G65 B;  2HII A;  1RXM A;  1CZD A;  2HIK C;  1GE8 A;  5E0T A;  3V61 B;  4L60 A;  2IZO C;  3P87 A;  3GGR A;  2IJX A;  3FDS D;  3VKX A;  4HK1 A;  1T6L A;  1ISQ A;  2IX2 B;  2NTI B;  5A6D A;  2HII B;  3V60 B;  2IX2 A;  2NTI A;  1DML A;  3IFV A;  1VYM A;  1U76 A;  5IXA A;  3K4X A;  3TBL A;  2ZVM A;  2AWA A;  3GGR B; 
#chains in the Genus database with same CATH homology
 3A1J A;  5H0T A;  4D2G A;  4CS5 A;  5E0U A;  2OD8 A;  3A2F B;  4RJF A;  3G65 C;  3P83 A;  4L6P A;  1PLR A;  1YYP A;  2HIK B;  5AUJ A;  3GPN A;  2IZO B;  2HIK A;  1IZ4 A;  3U61 F;  1W60 A;  3LX1 A;  2ZVK A;  1VYJ A;  3A1J B;  3WGW A;  3LX2 A;  5E0V A;  2HII C;  2AVT A;  2ZVL A;  5IWD A;  3U60 F;  4ZTD A;  5DA7 A;  1SXJ F;  3P91 A;  1U7B A;  4YHR A;  1B77 A;  3GGR C;  5DAI A;  3AIX A;  3U5Z F;  1RWZ A;  3HI8 A;  2IO4 B;  3G65 A;  3F1W A;  5CFK A;  1UL1 A;  1AXC A;  2IX2 C;  3AIZ C;  2NTI C;  5IY4 A;  2IO4 A;  5B7O A;  1IZ5 A;  2ZVV A;  1B8H A;  3FDS C;  2Z0L A;  3I2M X;  5JNE D;  3A1J C;  3GPM A;  3AIX B;  1UD9 A;  5HAC A;  3V62 B;  3AIZ A;  4TR6 A;  3HSL X;  1PLQ A;  1RXZ A;  2ZVW A;  3G65 B;  2HII A;  1RXM A;  1CZD A;  2HIK C;  1GE8 A;  5E0T A;  3V61 B;  4L60 A;  2IZO C;  3P87 A;  3GGR A;  2IJX A;  3FDS D;  3VKX A;  4HK1 A;  1T6L A;  1ISQ A;  2IX2 B;  2NTI B;  5A6D A;  2HII B;  3V60 B;  2IX2 A;  2NTI A;  1DML A;  3IFV A;  1VYM A;  1U76 A;  5IXA A;  3K4X A;  3TBL A;  2ZVM A;  2AWA A;  3GGR B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...