2O5JD

Crystal structure of the t. thermophilus rnap polymerase elongation complex with the ntp substrate analog
Total Genus 275
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
275
sequence length
1504
structure length
1264
Chain Sequence
KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGAADITQGLPRVIELFEARRPKAKAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEAVEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for substrate loading in bacterial RNA polymerase.
pubmed doi rcsb
molecule keywords 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP
molecule tags Transferase/dna-rna hybrid
total genus 275
structure length 1264
sequence length 1504
chains with identical sequence N
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2006-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00623 RNA_pol_Rpb1_2 RNA polymerase Rpb1, domain 2
D PF04983 RNA_pol_Rpb1_3 RNA polymerase Rpb1, domain 3
D PF04997 RNA_pol_Rpb1_1 RNA polymerase Rpb1, domain 1
D PF04998 RNA_pol_Rpb1_5 RNA polymerase Rpb1, domain 5
D PF05000 RNA_pol_Rpb1_4 RNA polymerase Rpb1, domain 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.30 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 2o5jD05
1.10.274.100 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2o5jD04
2.20.28.170 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2o5jD07
2.40.40.70 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2o5jD03
1R9TA 3GTOA 1TWHA 2NVXA 1I6VD 1YNJD 2Y0SA 2A6HD 2PMZA 4AYBA 3HKZA 1I50A 3GTJA 4C2MA 2YU9A 3GTQA 1TWGA 3FKIA 2A6ED 3GTGA 3GTMA 2E2HA 2JA5A 2R92A 2O5JD 3CQZA 2A68D 2JA6A 3GTKA 2R7ZA 1SMYD 2R93A 1K83A 2VUMA 1Y1WA 2B63A 2E2IA 4QIWA 1TWCA 1HQMD 3GTPA 2CW0D 2A69D 1WCMA 2BE5D 1TWFA 2NVYA 1I3QA 3H0GA 1Y1VA 1IW7D 1TWAA 1YNND 2WAQA 1ZYRD 2WB1A 3GTLA 2JA7A 1SFOA
chains in the Genus database with same CATH superfamily
4AHWA 1PFVA 3SULA 5M5XL 4C5UA 1IU5A 1K4SA 1ZRPA 1Q16A 2C45A 4GA5A 1MIUA 4F3EA 4Q5GA 2R7ZA 4TPUA 2B63A 4XXBB 2MX8A 2GMGA 3EZEA 3S1ML 1UHDA 3QVDA 5DYGA 1CR5A 1JYBA 1HQMD 1NXEA 1H5NA 1I50L 4CEHA 1BE7A 1T8IA 2RFKB 1UHEA 2ENGA 3O5AA 1YK4A 1ZYRD 3PIP1 2C6AA 3LPEB 2VK9A 4CRYG 3H99A 1RDVA 3DU6A 2PMZP 2K3OA 2FIPA 2PMZA 3LF9A 1IU6A 5AI3A 3X2GA 4V196 5IYDL 1SMMA 1WCML 2JIRA 5GLXA 4A3FL 5IZ2A 3U4QA 4AR5A 5AI2A 3H0GL 1RR8C 3HOVL 4DMRA 1T6JA 1SFOL 1CZ5A 2R93A 4QIWP 5MGNA 1OWCA 1E8JA 4WFN1 1R49A 3MQKB 5B6CA 2CW0D 1FDOA 1NXGA 1ODHA 1QDNA 3FDJA 2NYAA 1Y1VA 3PLXB 2XJVA 5GM9A 5T5ID 5GLFA 1DD5A 1NH3A 2B9SB 1HD5A 4AI2A 1DVBA 2CR8A 4B8CD 4D3ZA 1W27A 1IS1A 2JA5A 1BFYA 1DMSA 3K59A 4JP7A 2KN9A 3S1RL 3WVOA 3P2AA 1RDGA 5GAEc 3LNLA 3K7AL 1OA7A 3CZBA 1YUZA 4JJOA 4FGUA 2VPYA 5C9HA 1EZBA 2H12A 2YU9L 3X2MA 1RYQA 2V3BB 2BE5D 5GLYA 2CKAA 2GAEA 1R9TA 1Y698 4NOHA 3HU3A 1EJ9A 1YNJD 4A3JL 2VPZA 2V45A 1EU1A 4KB4A 3DMRA 5IP9L 2F5JA 2V3VA 4ME3A 1L8FA 4AR4A 2EY4E 1SMYD 3KYXA 3M3GA 3HOWL 1Y1WA 3WWNB 1WQHA 4XGHA 2E2IA 3KYUA 4A3ML 3GTOL 2JIPA 1S2ZA 5MLC3 1OA9A 3IAYA 2F4QA 2E2HL 5C18A 2WAQP 3GTML 1NNQA 3GTLA 4BAAA 3H3VM 3CQZL 2NVQL 3RYGA 1K4TA 1G8JA 4ZN3B 1E5VA 1V9MA 2R4GA 5M5YL 2XJSA 4AYBA 3H9BA 1S24A 1TWCL 4CRZA 3GTGA 2ERSA 1R0GA 5MF6A 4ENGA 2R92A 3S16L 4KDIA 4C5SA 1Y2MA 1I3QL 2HCZX 1PT1A 3D30A 3HJYB 3GTKA 1S30A 1R0FA 4D7ZB 4GFQA 2YUJA 1IRNA 5MLC9 2FIOA 2V0EA 4RXNA 3K5OA 5DYIA 2VL6A 3S2HL 4KB2A 3FKIL 1B13A 4NOKA 1I6HL 4H3TA 2JA7A 2WB1A 1T9OA 2PVEA 4A3IL 1H7VA 4Y7NL 4IP8A 1QYBA 3CF2A 1OGYA 3U44A 4C2MA 4AONB 4JP6A 3LR6A 5CQGA 5FTNA 4BY1L 1FHHA 3LR8A 4G6BA 3H9CA 2KI8A 1DMRA 3PZAA 1VZHA 4FERA 6RXNA 2C6BA 5JVH1 1CZ4A 2AQLA 4A3LL 3PKJA 3GTPA 3GTQL 4KLNA 4CEJA 2MX9A 2X0QA 1F4LA 5MFZA 1TWFA 2EEOB 4A3BL 2PICA 2XJPA 3LR2A 3LRDA 1PT0A 5GADc 3HAXC 1BQ8A 5FTKA 3WWLA 3X2KA 5AN9H 3NFPI 4BBSL 3KYLA 1PFUA 3SJRA 2A6HD 1Z92B 1T9PA 1E60A 4AZDA 3X2OA 4AHYA 5FTLA 3M3YL 1ISEA 3LHPS 3SS2A 2PYAA 5C1BA 1ZYMA 1LKMA 3KYWA 4KAWX 2JA6A 1RYTA 2VUMA 1K83A 4FFTA 4A3CL 4QIWA 1TWHL 2KKDA 1B71A 1VCXA 2NVXL 1PYQA 3GTJL 2A69D 2E7ZA 3S15L 1TWGL 4C3IL 1FDIA 2EZAA 3ML1A 4CS0A 1IROA 2LKMB 2QL0A 4LMOA 4C2M1 1DX8A 3K35A 3GTOA 2Y0SP 2AYJA 1BW3A 1YV1A 4KODA 4NOMA 7RXNA 1RWDA 2PI8A 3GTMA 5GAGc 3VPBE 1R7RA 4AVRA 3K5MA 1QCSA 5JVG1 4Y52L 3OUGA 5M3FL 3K57A 4E6YA 2X0OA 4LHLA 4U671 5EIOC 3DU5A 3MAQA 4AAYA 2JI3A 2CKCA 2LYIA 4K9FA 1E61A 3J7Z1 2JI2A 3PIO1 2NVYA 1TGOA 1Y5IA 2PJHB 1TWAA 3S1NL 2JIMA 2R7ZL 1R5ZA 2B63L 3HKZP 2VPXA 3QWZA 5MFPA 2KQAA 3QC8A 2LPIA 5DM71 4JLRC 4LHNA 4C5RA 1EH1A 4AI3A 1A35A 2JA8L 3TIWA 2MQAA 2B5ID 3KYVA 5C3EL 1P7PA 1RB9A 2XJRA 1PYUB 1AW8B 4A3GL 5K2ME 1SMUA 4X6AL 1CAAA 2NYDA 3PKIA 2AQCA 4V2QA 2WAQA 3SUKA 2Y0NA 1EK8A 2JI1A 2R93L 2E2JL 2Z3RB 1WJVA 3PWFA 1I50A 1SC7A 3ZG6A 1PZXA 4KC6A 5M3ML 4AOKB 4KDDA 4FXDA 4QCLA 2O5JD 1Y1VL 2LPJA 3LWOB 2HWGA 4JAEA 2IV2X 4RV0A 4ZN1B 3LWVB 1LPQA 4KDLA 3ENGA 3M4OL 1WCMA 1EZAA 1H0HA 2M4VA 2JA5L 2JIOA 3PO2L 4L48A 1TMOA 3H0GA 2J9UB 1E18A 1SFOA 2APOB 2M6OA 1SEUA 4A3EL 1R0IA 3K5NA 3HOZL 1PQEA 4JAGA 2MS3A 1LTLA 2A6ED 4GS7D 3HJWB 3H97A 1KQGA 5JSNB 2LTHA 2M6PA 4FBSA 2EZCA 1LKPA 1R9TL 4CQ5A 2NAPA 4JAFA 5JSBB 2HROA 2EZBA 2MP0A 1YK5A 2G5DA 1AA6A 4BABA 4BY7L 1SIWA 3K5LA 2JIQA 3X2IA 3LWPB 3S17L 3B08B 1Y1WL 2E2IL 3HOXL 2YU9A 4OYDB 2X0PA 1A31A 1B2JA 4C3HL 4A3DL 5FTMA 4JCWA 2XJQA 3GTLL 3S1QL 3P9AA 4FG4A 2K3NA 4O26A 1VZGA 4KO8A 2HVYC 3TM7B 2DMRA 3M4AA 3RZDL 3GTGL 2R92L 3LWQB 2XJTA 1IW7D 3RZTA 1YLEA 5FJ8L 3MSUA 3JR7A 4TVMA 4C3JL 3GTKL 3IR6A 3RZOL 3K58A 1VC3B 2YIIA 1OWBA 4FG2A 3SUJA 5RXNA 2Y0SA 3HOUL 2BH0A 2NVTL 4CEIA 4POGA 3NZ4A 2ERJA 2E2HA 4POFA 1R27A 1BRFA 1BW4A 5M5WL 3QQCE 5C4XL 2JA7L 3CQZA 4NOLA 4JS7A 5T5MD 5GAHc 4AI1A 4AHCA 3S14L 1WLFA 4C6GA 1QQTA 1TWCA 3HU1A 3IU3I 5DM61 3PO3L 5H1Sc 2PPTA 1I3QA 4AI0A 1SMWA 1T6PA 1YNND 3S2DL 5FTJA 4FYDA 5IY0A 1Q8IA 4EJ3A 1I6VD 1A36A 3B0AB 2PSMC 3HKZA 3FKIA 3GTPL 1B2OA 3KYYA 4A3KL 2PJJA 4IP9A 1TWFL 1WQGA 2L0ZA 1R0HA 1R0JA 2K3QA 3LWRB 4JADA 4GA6A 3HU2A 1ZC1A 3IR5A 5IYCL 1C09A 3MPSA 2ZIXA 1FHMA 1QCVA 4YWLA 2JA6L 1S3SA 4D3YA 2DSXA 2PVXA 4AR3A 5EINC 3X2PA 2VUML 1K83L 2AE0X 2LCQA 1TL8A 3X2HA 3PL5A 3GTQA 4L8IA 3QQ8A 2HR5A 1Y4ZA 5H4UA 3X2JA 4BBRL 2VPWA 2A68D 3EZBA 3IR7A 2RDVA 4YWMA 4Q5VA 1BQ9A 1PQHA 1PFWA 1WQFA 2V0FA 3J7Y1 1N10A 4V2RA 2Z3QB 3RZ6A 5C4JL 1E32A 2M4YA 3X2LA 3SUMA 2N3EA 1KQFA 1LKOA 3I4ML 1T9QA 4AR6A 3EZAA 1RRJA 4AYBP 5FLML 1TWHA 2NVXA 3A44A 5EPPA 3GTJA 4BXXL 1TWGA 1PFYA 4UY81 2PNWA 2N1DB 4AN8A 1PQFA 3QQ7A 1YUXA 1GE9A 2NVYL 1TWAL 2XJUA 4AHZA 3HOYL 1PPYA 5IYBL 2AUSB 2K2DA 8RXNA 5C44L 3P8BA 3I4NL 2G6GA 1WC2A 1G8KA 2WB1P 3X2NA 4ZM7A 4A93L 1VZIA 1CADA 4AHXA 5IP7L
chains in the Genus database with same CATH topology
4AHWA 1IU5A 1K4SA 1ZRPA 1Q16A 2C45A 4GA5A 1MIUA 4F3EA 4Q5GA 2R7ZA 4TPUA 2B63A 4XXBB 2MX8A 2GMGA 1UHDA 3QVDA 5DYGA 1CR5A 1JYBA 1HQMD 1NXEA 1H5NA 4CEHA 1BE7A 1T8IA 1UHEA 3O5AA 1YK4A 1ZYRD 3PIP1 2C6AA 3LPEB 2VK9A 4CRYG 1RDVA 3DU6A 2K3OA 2FIPA 2PMZA 3LF9A 1IU6A 5AI3A 4V196 1SMMA 2JIRA 5IZ2A 3U4QA 4AR5A 5AI2A 1RR8C 4DMRA 1CZ5A 2R93A 5MGNA 1OWCA 1E8JA 4WFN1 1R49A 5B6CA 2CW0D 1FDOA 1NXGA 1ODHA 1QDNA 2NYAA 5T5ID 1Y1VA 3PLXB 2XJVA 5GLFA 1DD5A 1NH3A 2B9SB 4AI2A 1DVBA 2CR8A 4B8CD 4D3ZA 1IS1A 2JA5A 1BFYA 1DMSA 3K59A 2KN9A 3WVOA 3P2AA 1RDGA 5GAEc 3LNLA 3CZBA 1YUZA 4FGUA 2VPYA 5C9HA 2H12A 1RYQA 2V3BB 2BE5D 2CKAA 2GAEA 1R9TA 1Y698 4NOHA 3HU3A 1EJ9A 1YNJD 2VPZA 2V45A 1EU1A 4KB4A 3DMRA 2F5JA 2V3VA 4ME3A 4AR4A 3KYXA 1SMYD 1Y1WA 3WWNB 1WQHA 4XGHA 2E2IA 3KYUA 2JIPA 1S2ZA 5MLC3 3IAYA 2F4QA 5C18A 1NNQA 3GTLA 3RYGA 1K4TA 1G8JA 4ZN3B 1E5VA 1V9MA 2R4GA 2XJSA 4AYBA 1S24A 4CRZA 3GTGA 2ERSA 1R0GA 5MF6A 2R92A 4KDIA 1PT1A 3GTKA 1S30A 1R0FA 4D7ZB 4GFQA 2YUJA 1IRNA 5MLC9 2FIOA 2V0EA 4RXNA 3K5OA 5DYIA 2VL6A 4KB2A 1B13A 4NOKA 4H3TA 2JA7A 2WB1A 1T9OA 2PVEA 1H7VA 4IP8A 1QYBA 3CF2A 1OGYA 3U44A 4C2MA 4AONB 3LR6A 5CQGA 5FTNA 1FHHA 3LR8A 4G6BA 2KI8A 1DMRA 3PZAA 1VZHA 6RXNA 2C6BA 5JVH1 1CZ4A 2AQLA 3PKJA 3GTPA 4KLNA 4CEJA 2MX9A 2X0QA 5MFZA 1TWFA 2EEOB 2PICA 2XJPA 3LR2A 3LRDA 1PT0A 5GADc 1BQ8A 5FTKA 3WWLA 5AN9H 3NFPI 3KYLA 1Z92B 3SJRA 2A6HD 1E60A 1T9PA 4AZDA 4AHYA 5FTLA 1ISEA 3LHPS 3SS2A 2PYAA 5C1BA 1LKMA 3KYWA 4KAWX 2JA6A 1RYTA 2VUMA 1K83A 4QIWA 1B71A 1VCXA 2KKDA 1PYQA 2A69D 2E7ZA 1FDIA 3ML1A 4CS0A 1IROA 2LKMB 2QL0A 4LMOA 1DX8A 3K35A 3GTOA 2AYJA 1YV1A 4KODA 4NOMA 7RXNA 1RWDA 2PI8A 3GTMA 5GAGc 3VPBE 1R7RA 3K5MA 1QCSA 5JVG1 3OUGA 3K57A 4E6YA 2X0OA 4LHLA 4U671 5EIOC 3DU5A 3MAQA 4AAYA 2JI3A 2CKCA 2LYIA 4K9FA 1E61A 3J7Z1 2JI2A 3PIO1 2NVYA 1TGOA 1Y5IA 2PJHB 1TWAA 2JIMA 1R5ZA 2VPXA 3QWZA 5MFPA 3QC8A 2LPIA 5DM71 4JLRC 4LHNA 4AI3A 1EH1A 1A35A 3TIWA 2MQAA 2B5ID 3KYVA 1RB9A 2XJRA 1PYUB 1AW8B 5K2ME 1SMUA 1CAAA 2NYDA 3PKIA 2WAQA 2Y0NA 1EK8A 2JI1A 2Z3RB 1WJVA 3PWFA 1I50A 1SC7A 3ZG6A 4AOKB 4KC6A 4KDDA 4FXDA 4QCLA 2O5JD 2LPJA 4JAEA 2IV2X 4RV0A 4ZN1B 1LPQA 4KDLA 1WCMA 1H0HA 2M4VA 2JIOA 1TMOA 3H0GA 2J9UB 1E18A 1SFOA 2M6OA 1SEUA 1R0IA 3K5NA 1PQEA 4JAGA 2MS3A 1LTLA 2A6ED 4GS7D 1KQGA 5JSNB 2LTHA 2M6PA 4FBSA 1LKPA 2NAPA 4JAFA 5JSBB 1YK5A 2G5DA 1AA6A 2JIQA 1SIWA 3K5LA 3B08B 2YU9A 4OYDB 2X0PA 1A31A 1B2JA 5FTMA 2XJQA 3P9AA 2K3NA 4O26A 1VZGA 4KO8A 3TM7B 2DMRA 3M4AA 2XJTA 1IW7D 3RZTA 1YLEA 3MSUA 4TVMA 3IR6A 3K58A 1VC3B 1OWBA 5RXNA 2Y0SA 4CEIA 4POGA 2ERJA 2E2HA 4POFA 1R27A 1BRFA 3QQCE 3CQZA 4NOLA 5T5MD 5GAHc 4AI1A 4AHCA 1WLFA 1TWCA 3HU1A 3IU3I 5DM61 5H1Sc 2PPTA 1I3QA 4AI0A 1SMWA 1YNND 5FTJA 4FYDA 5IY0A 1Q8IA 4EJ3A 1I6VD 1A36A 3B0AB 2PSMC 3HKZA 3FKIA 1B2OA 3KYYA 2PJJA 4IP9A 1WQGA 2L0ZA 1R0HA 1R0JA 2K3QA 4JADA 4GA6A 3HU2A 1ZC1A 3IR5A 1C09A 3MPSA 2ZIXA 1FHMA 1QCVA 4YWLA 1S3SA 4D3YA 2DSXA 2PVXA 4AR3A 5EINC 2AE0X 2LCQA 1TL8A 3GTQA 4L8IA 3QQ8A 2HR5A 1Y4ZA 2VPWA 2A68D 3IR7A 2RDVA 4YWMA 4Q5VA 1BQ9A 1PQHA 1WQFA 2V0FA 3J7Y1 2Z3QB 3RZ6A 1E32A 2M4YA 2N3EA 1KQFA 1LKOA 1T9QA 4AR6A 1RRJA 1TWHA 2NVXA 3A44A 5EPPA 3GTJA 1TWGA 4UY81 2PNWA 2N1DB 4AN8A 1PQFA 3QQ7A 1YUXA 1GE9A 2XJUA 4AHZA 1PPYA 2K2DA 8RXNA 3P8BA 2G6GA 1G8KA 1VZIA 1CADA 4AHXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R9T A;  3GTO A;  1TWH A;  2NVX A;  1I6V D;  1YNJ D;  2Y0S A;  2A6H D;  2PMZ A;  4AYB A;  3HKZ A;  1I50 A;  3GTJ A;  4C2M A;  2YU9 A;  3GTQ A;  1TWG A;  3FKI A;  2A6E D;  3GTG A;  3GTM A;  2E2H A;  2JA5 A;  2R92 A;  2O5J D;  3CQZ A;  2A68 D;  2JA6 A;  3GTK A;  2R7Z A;  1SMY D;  2R93 A;  1K83 A;  2VUM A;  1Y1W A;  2B63 A;  2E2I A;  4QIW A;  1TWC A;  1HQM D;  3GTP A;  2CW0 D;  2A69 D;  1WCM A;  2BE5 D;  1TWF A;  2NVY A;  1I3Q A;  3H0G A;  1Y1V A;  1IW7 D;  1TWA A;  1YNN D;  2WAQ A;  1ZYR D;  2WB1 A;  3GTL A;  2JA7 A;  1SFO A; 
#chains in the Genus database with same CATH topology
 4AHW A;  1PFV A;  3SUL A;  5M5X L;  4C5U A;  1IU5 A;  1K4S A;  1ZRP A;  1Q16 A;  2C45 A;  4GA5 A;  1MIU A;  4F3E A;  4Q5G A;  2R7Z A;  4TPU A;  2B63 A;  4XXB B;  2MX8 A;  2GMG A;  3EZE A;  3S1M L;  1UHD A;  3QVD A;  5DYG A;  1CR5 A;  1JYB A;  1HQM D;  1NXE A;  1H5N A;  1I50 L;  4CEH A;  1BE7 A;  1T8I A;  2RFK B;  1UHE A;  2ENG A;  3O5A A;  1YK4 A;  1ZYR D;  3PIP 1;  2C6A A;  3LPE B;  2VK9 A;  4CRY G;  3H99 A;  1RDV A;  3DU6 A;  2PMZ P;  2K3O A;  2FIP A;  2PMZ A;  3LF9 A;  1IU6 A;  5AI3 A;  3X2G A;  4V19 6;  5IYD L;  1SMM A;  1WCM L;  2JIR A;  5GLX A;  4A3F L;  5IZ2 A;  3U4Q A;  4AR5 A;  5AI2 A;  3H0G L;  1RR8 C;  3HOV L;  4DMR A;  1T6J A;  1SFO L;  1CZ5 A;  2R93 A;  4QIW P;  5MGN A;  1OWC A;  1E8J A;  4WFN 1;  1R49 A;  3MQK B;  5B6C A;  2CW0 D;  1FDO A;  1NXG A;  1ODH A;  1QDN A;  3FDJ A;  2NYA A;  1Y1V A;  3PLX B;  2XJV A;  5GM9 A;  5T5I D;  5GLF A;  1DD5 A;  1NH3 A;  2B9S B;  1HD5 A;  4AI2 A;  1DVB A;  2CR8 A;  4B8C D;  4D3Z A;  1W27 A;  1IS1 A;  2JA5 A;  1BFY A;  1DMS A;  3K59 A;  4JP7 A;  2KN9 A;  3S1R L;  3WVO A;  3P2A A;  1RDG A;  5GAE c;  3LNL A;  3K7A L;  1OA7 A;  3CZB A;  1YUZ A;  4JJO A;  4FGU A;  2VPY A;  5C9H A;  1EZB A;  2H12 A;  2YU9 L;  3X2M A;  1RYQ A;  2V3B B;  2BE5 D;  5GLY A;  2CKA A;  2GAE A;  1R9T A;  1Y69 8;  4NOH A;  3HU3 A;  1EJ9 A;  1YNJ D;  4A3J L;  2VPZ A;  2V45 A;  1EU1 A;  4KB4 A;  3DMR A;  5IP9 L;  2F5J A;  2V3V A;  4ME3 A;  1L8F A;  4AR4 A;  2EY4 E;  1SMY D;  3KYX A;  3M3G A;  3HOW L;  1Y1W A;  3WWN B;  1WQH A;  4XGH A;  2E2I A;  3KYU A;  4A3M L;  3GTO L;  2JIP A;  1S2Z A;  5MLC 3;  1OA9 A;  3IAY A;  2F4Q A;  2E2H L;  5C18 A;  2WAQ P;  3GTM L;  1NNQ A;  3GTL A;  4BAA A;  3H3V M;  3CQZ L;  2NVQ L;  3RYG A;  1K4T A;  1G8J A;  4ZN3 B;  1E5V A;  1V9M A;  2R4G A;  5M5Y L;  2XJS A;  4AYB A;  3H9B A;  1S24 A;  1TWC L;  4CRZ A;  3GTG A;  2ERS A;  1R0G A;  5MF6 A;  4ENG A;  2R92 A;  3S16 L;  4KDI A;  4C5S A;  1Y2M A;  1I3Q L;  2HCZ X;  1PT1 A;  3D30 A;  3HJY B;  3GTK A;  1S30 A;  1R0F A;  4D7Z B;  4GFQ A;  2YUJ A;  1IRN A;  5MLC 9;  2FIO A;  2V0E A;  4RXN A;  3K5O A;  5DYI A;  2VL6 A;  3S2H L;  4KB2 A;  3FKI L;  1B13 A;  4NOK A;  1I6H L;  4H3T A;  2JA7 A;  2WB1 A;  1T9O A;  2PVE A;  4A3I L;  1H7V A;  4Y7N L;  4IP8 A;  1QYB A;  3CF2 A;  1OGY A;  3U44 A;  4C2M A;  4AON B;  4JP6 A;  3LR6 A;  5CQG A;  5FTN A;  4BY1 L;  1FHH A;  3LR8 A;  4G6B A;  3H9C A;  2KI8 A;  1DMR A;  3PZA A;  1VZH A;  4FER A;  6RXN A;  2C6B A;  5JVH 1;  1CZ4 A;  2AQL A;  4A3L L;  3PKJ A;  3GTP A;  3GTQ L;  4KLN A;  4CEJ A;  2MX9 A;  2X0Q A;  1F4L A;  5MFZ A;  1TWF A;  2EEO B;  4A3B L;  2PIC A;  2XJP A;  3LR2 A;  3LRD A;  1PT0 A;  5GAD c;  3HAX C;  1BQ8 A;  5FTK A;  3WWL A;  3X2K A;  5AN9 H;  3NFP I;  4BBS L;  3KYL A;  1PFU A;  3SJR A;  2A6H D;  1Z92 B;  1T9P A;  1E60 A;  4AZD A;  3X2O A;  4AHY A;  5FTL A;  3M3Y L;  1ISE A;  3LHP S;  3SS2 A;  2PYA A;  5C1B A;  1ZYM A;  1LKM A;  3KYW A;  4KAW X;  2JA6 A;  1RYT A;  2VUM A;  1K83 A;  4FFT A;  4A3C L;  4QIW A;  1TWH L;  2KKD A;  1B71 A;  1VCX A;  2NVX L;  1PYQ A;  3GTJ L;  2A69 D;  2E7Z A;  3S15 L;  1TWG L;  4C3I L;  1FDI A;  2EZA A;  3ML1 A;  4CS0 A;  1IRO A;  2LKM B;  2QL0 A;  4LMO A;  4C2M 1;  1DX8 A;  3K35 A;  3GTO A;  2Y0S P;  2AYJ A;  1BW3 A;  1YV1 A;  4KOD A;  4NOM A;  7RXN A;  1RWD A;  2PI8 A;  3GTM A;  5GAG c;  3VPB E;  1R7R A;  4AVR A;  3K5M A;  1QCS A;  5JVG 1;  4Y52 L;  3OUG A;  5M3F L;  3K57 A;  4E6Y A;  2X0O A;  4LHL A;  4U67 1;  5EIO C;  3DU5 A;  3MAQ A;  4AAY A;  2JI3 A;  2CKC A;  2LYI A;  4K9F A;  1E61 A;  3J7Z 1;  2JI2 A;  3PIO 1;  2NVY A;  1TGO A;  1Y5I A;  2PJH B;  1TWA A;  3S1N L;  2JIM A;  2R7Z L;  1R5Z A;  2B63 L;  3HKZ P;  2VPX A;  3QWZ A;  5MFP A;  2KQA A;  3QC8 A;  2LPI A;  5DM7 1;  4JLR C;  4LHN A;  4C5R A;  1EH1 A;  4AI3 A;  1A35 A;  2JA8 L;  3TIW A;  2MQA A;  2B5I D;  3KYV A;  5C3E L;  1P7P A;  1RB9 A;  2XJR A;  1PYU B;  1AW8 B;  4A3G L;  5K2M E;  1SMU A;  4X6A L;  1CAA A;  2NYD A;  3PKI A;  2AQC A;  4V2Q A;  2WAQ A;  3SUK A;  2Y0N A;  1EK8 A;  2JI1 A;  2R93 L;  2E2J L;  2Z3R B;  1WJV A;  3PWF A;  1I50 A;  1SC7 A;  3ZG6 A;  1PZX A;  4KC6 A;  5M3M L;  4AOK B;  4KDD A;  4FXD A;  4QCL A;  2O5J D;  1Y1V L;  2LPJ A;  3LWO B;  2HWG A;  4JAE A;  2IV2 X;  4RV0 A;  4ZN1 B;  3LWV B;  1LPQ A;  4KDL A;  3ENG A;  3M4O L;  1WCM A;  1EZA A;  1H0H A;  2M4V A;  2JA5 L;  2JIO A;  3PO2 L;  4L48 A;  1TMO A;  3H0G A;  2J9U B;  1E18 A;  1SFO A;  2APO B;  2M6O A;  1SEU A;  4A3E L;  1R0I A;  3K5N A;  3HOZ L;  1PQE A;  4JAG A;  2MS3 A;  1LTL A;  2A6E D;  4GS7 D;  3HJW B;  3H97 A;  1KQG A;  5JSN B;  2LTH A;  2M6P A;  4FBS A;  2EZC A;  1LKP A;  1R9T L;  4CQ5 A;  2NAP A;  4JAF A;  5JSB B;  2HRO A;  2EZB A;  2MP0 A;  1YK5 A;  2G5D A;  1AA6 A;  4BAB A;  4BY7 L;  1SIW A;  3K5L A;  2JIQ A;  3X2I A;  3LWP B;  3S17 L;  3B08 B;  1Y1W L;  2E2I L;  3HOX L;  2YU9 A;  4OYD B;  2X0P A;  1A31 A;  1B2J A;  4C3H L;  4A3D L;  5FTM A;  4JCW A;  2XJQ A;  3GTL L;  3S1Q L;  3P9A A;  4FG4 A;  2K3N A;  4O26 A;  1VZG A;  4KO8 A;  2HVY C;  3TM7 B;  2DMR A;  3M4A A;  3RZD L;  3GTG L;  2R92 L;  3LWQ B;  2XJT A;  1IW7 D;  3RZT A;  1YLE A;  5FJ8 L;  3MSU A;  3JR7 A;  4TVM A;  4C3J L;  3GTK L;  3IR6 A;  3RZO L;  3K58 A;  1VC3 B;  2YII A;  1OWB A;  4FG2 A;  3SUJ A;  5RXN A;  2Y0S A;  3HOU L;  2BH0 A;  2NVT L;  4CEI A;  4POG A;  3NZ4 A;  2ERJ A;  2E2H A;  4POF A;  1R27 A;  1BRF A;  1BW4 A;  5M5W L;  3QQC E;  5C4X L;  2JA7 L;  3CQZ A;  4NOL A;  4JS7 A;  5T5M D;  5GAH c;  4AI1 A;  4AHC A;  3S14 L;  1WLF A;  4C6G A;  1QQT A;  1TWC A;  3HU1 A;  3IU3 I;  5DM6 1;  3PO3 L;  5H1S c;  2PPT A;  1I3Q A;  4AI0 A;  1SMW A;  1T6P A;  1YNN D;  3S2D L;  5FTJ A;  4FYD A;  5IY0 A;  1Q8I A;  4EJ3 A;  1I6V D;  1A36 A;  3B0A B;  2PSM C;  3HKZ A;  3FKI A;  3GTP L;  1B2O A;  3KYY A;  4A3K L;  2PJJ A;  4IP9 A;  1TWF L;  1WQG A;  2L0Z A;  1R0H A;  1R0J A;  2K3Q A;  3LWR B;  4JAD A;  4GA6 A;  3HU2 A;  1ZC1 A;  3IR5 A;  5IYC L;  1C09 A;  3MPS A;  2ZIX A;  1FHM A;  1QCV A;  4YWL A;  2JA6 L;  1S3S A;  4D3Y A;  2DSX A;  2PVX A;  4AR3 A;  5EIN C;  3X2P A;  2VUM L;  1K83 L;  2AE0 X;  2LCQ A;  1TL8 A;  3X2H A;  3PL5 A;  3GTQ A;  4L8I A;  3QQ8 A;  2HR5 A;  1Y4Z A;  5H4U A;  3X2J A;  4BBR L;  2VPW A;  2A68 D;  3EZB A;  3IR7 A;  2RDV A;  4YWM A;  4Q5V A;  1BQ9 A;  1PQH A;  1PFW A;  1WQF A;  2V0F A;  3J7Y 1;  1N10 A;  4V2R A;  2Z3Q B;  3RZ6 A;  5C4J L;  1E32 A;  2M4Y A;  3X2L A;  3SUM A;  2N3E A;  1KQF A;  1LKO A;  3I4M L;  1T9Q A;  4AR6 A;  3EZA A;  1RRJ A;  4AYB P;  5FLM L;  1TWH A;  2NVX A;  3A44 A;  5EPP A;  3GTJ A;  4BXX L;  1TWG A;  1PFY A;  4UY8 1;  2PNW A;  2N1D B;  4AN8 A;  1PQF A;  3QQ7 A;  1YUX A;  1GE9 A;  2NVY L;  1TWA L;  2XJU A;  4AHZ A;  3HOY L;  1PPY A;  5IYB L;  2AUS B;  2K2D A;  8RXN A;  5C44 L;  3P8B A;  3I4N L;  2G6G A;  1WC2 A;  1G8K A;  2WB1 P;  3X2N A;  4ZM7 A;  4A93 L;  1VZI A;  1CAD A;  4AHX A;  5IP7 L; 
#chains in the Genus database with same CATH homology
 4AHW A;  1IU5 A;  1K4S A;  1ZRP A;  1Q16 A;  2C45 A;  4GA5 A;  1MIU A;  4F3E A;  4Q5G A;  2R7Z A;  4TPU A;  2B63 A;  4XXB B;  2MX8 A;  2GMG A;  1UHD A;  3QVD A;  5DYG A;  1CR5 A;  1JYB A;  1HQM D;  1NXE A;  1H5N A;  4CEH A;  1BE7 A;  1T8I A;  1UHE A;  3O5A A;  1YK4 A;  1ZYR D;  3PIP 1;  2C6A A;  3LPE B;  2VK9 A;  4CRY G;  1RDV A;  3DU6 A;  2K3O A;  2FIP A;  2PMZ A;  3LF9 A;  1IU6 A;  5AI3 A;  4V19 6;  1SMM A;  2JIR A;  5IZ2 A;  3U4Q A;  4AR5 A;  5AI2 A;  1RR8 C;  4DMR A;  1CZ5 A;  2R93 A;  5MGN A;  1OWC A;  1E8J A;  4WFN 1;  1R49 A;  5B6C A;  2CW0 D;  1FDO A;  1NXG A;  1ODH A;  1QDN A;  2NYA A;  5T5I D;  1Y1V A;  3PLX B;  2XJV A;  5GLF A;  1DD5 A;  1NH3 A;  2B9S B;  4AI2 A;  1DVB A;  2CR8 A;  4B8C D;  4D3Z A;  1IS1 A;  2JA5 A;  1BFY A;  1DMS A;  3K59 A;  2KN9 A;  3WVO A;  3P2A A;  1RDG A;  5GAE c;  3LNL A;  3CZB A;  1YUZ A;  4FGU A;  2VPY A;  5C9H A;  2H12 A;  1RYQ A;  2V3B B;  2BE5 D;  2CKA A;  2GAE A;  1R9T A;  1Y69 8;  4NOH A;  3HU3 A;  1EJ9 A;  1YNJ D;  2VPZ A;  2V45 A;  1EU1 A;  4KB4 A;  3DMR A;  2F5J A;  2V3V A;  4ME3 A;  4AR4 A;  3KYX A;  1SMY D;  1Y1W A;  3WWN B;  1WQH A;  4XGH A;  2E2I A;  3KYU A;  2JIP A;  1S2Z A;  5MLC 3;  3IAY A;  2F4Q A;  5C18 A;  1NNQ A;  3GTL A;  3RYG A;  1K4T A;  1G8J A;  4ZN3 B;  1E5V A;  1V9M A;  2R4G A;  2XJS A;  4AYB A;  1S24 A;  4CRZ A;  3GTG A;  2ERS A;  1R0G A;  5MF6 A;  2R92 A;  4KDI A;  1PT1 A;  3GTK A;  1S30 A;  1R0F A;  4D7Z B;  4GFQ A;  2YUJ A;  1IRN A;  5MLC 9;  2FIO A;  2V0E A;  4RXN A;  3K5O A;  5DYI A;  2VL6 A;  4KB2 A;  1B13 A;  4NOK A;  4H3T A;  2JA7 A;  2WB1 A;  1T9O A;  2PVE A;  1H7V A;  4IP8 A;  1QYB A;  3CF2 A;  1OGY A;  3U44 A;  4C2M A;  4AON B;  3LR6 A;  5CQG A;  5FTN A;  1FHH A;  3LR8 A;  4G6B A;  2KI8 A;  1DMR A;  3PZA A;  1VZH A;  6RXN A;  2C6B A;  5JVH 1;  1CZ4 A;  2AQL A;  3PKJ A;  3GTP A;  4KLN A;  4CEJ A;  2MX9 A;  2X0Q A;  5MFZ A;  1TWF A;  2EEO B;  2PIC A;  2XJP A;  3LR2 A;  3LRD A;  1PT0 A;  5GAD c;  1BQ8 A;  5FTK A;  3WWL A;  5AN9 H;  3NFP I;  3KYL A;  1Z92 B;  3SJR A;  2A6H D;  1E60 A;  1T9P A;  4AZD A;  4AHY A;  5FTL A;  1ISE A;  3LHP S;  3SS2 A;  2PYA A;  5C1B A;  1LKM A;  3KYW A;  4KAW X;  2JA6 A;  1RYT A;  2VUM A;  1K83 A;  4QIW A;  1B71 A;  1VCX A;  2KKD A;  1PYQ A;  2A69 D;  2E7Z A;  1FDI A;  3ML1 A;  4CS0 A;  1IRO A;  2LKM B;  2QL0 A;  4LMO A;  1DX8 A;  3K35 A;  3GTO A;  2AYJ A;  1YV1 A;  4KOD A;  4NOM A;  7RXN A;  1RWD A;  2PI8 A;  3GTM A;  5GAG c;  3VPB E;  1R7R A;  3K5M A;  1QCS A;  5JVG 1;  3OUG A;  3K57 A;  4E6Y A;  2X0O A;  4LHL A;  4U67 1;  5EIO C;  3DU5 A;  3MAQ A;  4AAY A;  2JI3 A;  2CKC A;  2LYI A;  4K9F A;  1E61 A;  3J7Z 1;  2JI2 A;  3PIO 1;  2NVY A;  1TGO A;  1Y5I A;  2PJH B;  1TWA A;  2JIM A;  1R5Z A;  2VPX A;  3QWZ A;  5MFP A;  3QC8 A;  2LPI A;  5DM7 1;  4JLR C;  4LHN A;  4AI3 A;  1EH1 A;  1A35 A;  3TIW A;  2MQA A;  2B5I D;  3KYV A;  1RB9 A;  2XJR A;  1PYU B;  1AW8 B;  5K2M E;  1SMU A;  1CAA A;  2NYD A;  3PKI A;  2WAQ A;  2Y0N A;  1EK8 A;  2JI1 A;  2Z3R B;  1WJV A;  3PWF A;  1I50 A;  1SC7 A;  3ZG6 A;  4AOK B;  4KC6 A;  4KDD A;  4FXD A;  4QCL A;  2O5J D;  2LPJ A;  4JAE A;  2IV2 X;  4RV0 A;  4ZN1 B;  1LPQ A;  4KDL A;  1WCM A;  1H0H A;  2M4V A;  2JIO A;  1TMO A;  3H0G A;  2J9U B;  1E18 A;  1SFO A;  2M6O A;  1SEU A;  1R0I A;  3K5N A;  1PQE A;  4JAG A;  2MS3 A;  1LTL A;  2A6E D;  4GS7 D;  1KQG A;  5JSN B;  2LTH A;  2M6P A;  4FBS A;  1LKP A;  2NAP A;  4JAF A;  5JSB B;  1YK5 A;  2G5D A;  1AA6 A;  2JIQ A;  1SIW A;  3K5L A;  3B08 B;  2YU9 A;  4OYD B;  2X0P A;  1A31 A;  1B2J A;  5FTM A;  2XJQ A;  3P9A A;  2K3N A;  4O26 A;  1VZG A;  4KO8 A;  3TM7 B;  2DMR A;  3M4A A;  2XJT A;  1IW7 D;  3RZT A;  1YLE A;  3MSU A;  4TVM A;  3IR6 A;  3K58 A;  1VC3 B;  1OWB A;  5RXN A;  2Y0S A;  4CEI A;  4POG A;  2ERJ A;  2E2H A;  4POF A;  1R27 A;  1BRF A;  3QQC E;  3CQZ A;  4NOL A;  5T5M D;  5GAH c;  4AI1 A;  4AHC A;  1WLF A;  1TWC A;  3HU1 A;  3IU3 I;  5DM6 1;  5H1S c;  2PPT A;  1I3Q A;  4AI0 A;  1SMW A;  1YNN D;  5FTJ A;  4FYD A;  5IY0 A;  1Q8I A;  4EJ3 A;  1I6V D;  1A36 A;  3B0A B;  2PSM C;  3HKZ A;  3FKI A;  1B2O A;  3KYY A;  2PJJ A;  4IP9 A;  1WQG A;  2L0Z A;  1R0H A;  1R0J A;  2K3Q A;  4JAD A;  4GA6 A;  3HU2 A;  1ZC1 A;  3IR5 A;  1C09 A;  3MPS A;  2ZIX A;  1FHM A;  1QCV A;  4YWL A;  1S3S A;  4D3Y A;  2DSX A;  2PVX A;  4AR3 A;  5EIN C;  2AE0 X;  2LCQ A;  1TL8 A;  3GTQ A;  4L8I A;  3QQ8 A;  2HR5 A;  1Y4Z A;  2VPW A;  2A68 D;  3IR7 A;  2RDV A;  4YWM A;  4Q5V A;  1BQ9 A;  1PQH A;  1WQF A;  2V0F A;  3J7Y 1;  2Z3Q B;  3RZ6 A;  1E32 A;  2M4Y A;  2N3E A;  1KQF A;  1LKO A;  1T9Q A;  4AR6 A;  1RRJ A;  1TWH A;  2NVX A;  3A44 A;  5EPP A;  3GTJ A;  1TWG A;  4UY8 1;  2PNW A;  2N1D B;  4AN8 A;  1PQF A;  3QQ7 A;  1YUX A;  1GE9 A;  2XJU A;  4AHZ A;  1PPY A;  2K2D A;  8RXN A;  3P8B A;  2G6G A;  1G8K A;  1VZI A;  1CAD A;  4AHX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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