2PQUA

Crystal structure of kh1 domain of human pcbp2 complexed to single-stranded 12-mer telomeric dna
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
72
structure length
72
Chain Sequence
KNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystallographic and NMR studies of protein-protein and protein-nucleic acid interactions involving the KH domains from human poly(C)-binding protein-2.
pubmed doi rcsb
molecule tags Rna and dna binding protein/dna
source organism Homo sapiens
molecule keywords 12-mer C-rich strand of human telomeric DNA
total genus 17
structure length 72
sequence length 72
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2007-05-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2pquA00
2CTEA 1J4WA 5JEAG 1ZTGA 4OO1G 2NN6G 1ZZKA 2DGRA 2Z0SA 3L7ZC 1WE8A 5C0XG 3U1KA 4AM3A 2HH2A 2CTLA 2ANRA 1J5KA 1X4MA 2OPUA 4AIMA 1ZZJA 2PQUA 1TUAA 1EC6A 4BA2I 2CTMA 2BA0A 1X4NA 2HH3A 2BL5A 2AXYA 4LIJA 2JA9A 5K36G 4JVHA 2CTJA 2YQRA 1ZZIA 3AEVB 2OPVA 4BA1I 4IFDG 2ANNA 4QMFB 2CTFA 2QNDA 2MJHA 2CTKA 4WALA 2CPQA 2JEBI 2JZXA 4NBQA 2JVZA 4B8TA 2P2RA 2JEAI 1WVNA 4JVYA 4WANA 1KHMA 3V69A 2E3UA 2PY9A 1K1GA 2JE6I 1DTJA 2FMRA 1VIHA 1VIGA 1DT4A 3VKEA
chains in the Genus database with same CATH superfamily
4FJUA 1J4WA 1ZTGA 4LF5H 4K0KH 2NN6G 1HNXH 1N32H 2F4VH 4EC5A 4NXNH 1Z2IA 4GKJH 5LMUH 4LF9H 3OSSD 1J5KA 4AIMA 1IBMH 4KHPH 4NZRM 4JI3H 1X4NA 1J5EH 1UG8A 2AXYA 2UUBH 1S03G 4DR4H 3KDKA 2VKCA 4PDBA 1V9NA 4DV6H 5LL6b 2VQFH 2CTFA 2ANNA 2CPMA 4WANA 5A2QW 1K1GA 3GKUA 2JE6I 2FMRA 5FLXW 4DV7H 1I6UA 1DT4A 1WHRA 1N33H 1HNWH 2FPHX 1HR0H 4JI4H 4B3RH 5JEAG 4OO1G 4JI8H 3UOEA 2UUAH 4JI1H 1WE8A 2M8WA 4OX9H 1SEIA 4LFAH 4JI0H 2FFMA 4NZTM 2CTLA 1FJGH 2VQEH 4DV3H 4LFCH 4X64H 1N34H 1ZZJA 4DR7H 5IWAH 4G08A 2BA0A 4LIJA 4DUYH 2CTJA 3AEVB 4IFDG 4OCHA 5DT9A 4E9JA 4YY3H 2CTKA 4WALA 2JZXA 2CWFA 2CWHA 4NBQA 4B8TA 2JEAI 1KHMA 3RF2A 1FKAH 3V69A 1NXUA 1VBIA 2PY9A 4JI5H 1VIHA 1F0XA 3I0PA 3T1HH 1MSZA 3VKEA 2CTEA 2G8YA 1IBKH 1ZZKA 4DR6H 3OETA 3OTOH 4DV4H 5C0XG 3L7ZC 2A1SA 4OD6A 1ODHA 4H8AA 4NXMH 4AM3A 2ZQEA 2Y3MA 2HH2A 1S20A 2HHHH 2LTMA 2X06A 4X66H 2PQUA 3SB1A 1TUAA 4DR2H 4JI7H 3KDGA 2BL5A 1HNZH 4LFBH 1PQXA 2UXCH 4FJSA 5K36G 2YQRA 1ZZIA 4B3TH 4LF6H 4BA1I 4DV2H 4LF8H 2E5LH 2QNDA 2MJHA 2UU9H 4JI6H 3J80W 2JEBI 4DUZH 4JYAH 1WVNA 1X0AA 3J81W 3T1YH 1DTJA 2LRRA 1AN7A 1VIGA 3GR5A 1V8CA 4LF4H 2K1HA 3JAMW 3J7AK 2PT7G 2UUCH 4X62H 2LTLA 3EZJA 2DGRA 3NCVA 1XMOH 2Z0SA 4GKKH 4DV5H 2UXDH 3U1KA 4AQYH 1I94H 4X65H 2ZM6H 2O4CA 2ANRA 4DR1H 3QD7X 5LMNH 4DR5H 5IT9W 1XRHA 1X4MA 2OPUA 5BR8H 4B3SH 1EC6A 4BA2I 2CTMA 2HH3A 3FAUA 2JA9A 4JI2H 1N36H 1XNQH 2D9IA 4JVHA 2OPVA 4B8CD 3GABA 4QMFB 4DR3H 2M6QA 1WTJA 2CPQA 2P2RA 2JVZA 4DV0H 4DV1H 1XNRH 4JVYA 4B3MH 1XMQH 2E3UA 1IBLH 2LF0A 4JV5H 1X9ZA 4YHHH 4LF7H 2UXBH
chains in the Genus database with same CATH topology
2CTEA 1J4WA 5JEAG 1ZTGA 4OO1G 2NN6G 1ZZKA 2DGRA 2Z0SA 3L7ZC 1WE8A 5C0XG 3U1KA 4AM3A 2HH2A 2CTLA 2ANRA 1J5KA 1X4MA 2OPUA 4AIMA 1ZZJA 2PQUA 1TUAA 1EC6A 4BA2I 2CTMA 2BA0A 1X4NA 2HH3A 2BL5A 2AXYA 4LIJA 2JA9A 5K36G 4JVHA 2CTJA 2YQRA 1ZZIA 3AEVB 2OPVA 4BA1I 4IFDG 2ANNA 4QMFB 2CTFA 2QNDA 2MJHA 2CTKA 4WALA 2CPQA 2JEBI 2JZXA 4NBQA 2JVZA 4B8TA 2P2RA 2JEAI 1WVNA 4JVYA 4WANA 1KHMA 3V69A 2E3UA 2PY9A 1K1GA 2JE6I 1DTJA 2FMRA 1VIHA 1VIGA 1DT4A 3VKEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CTE A;  1J4W A;  5JEA G;  1ZTG A;  4OO1 G;  2NN6 G;  1ZZK A;  2DGR A;  2Z0S A;  3L7Z C;  1WE8 A;  5C0X G;  3U1K A;  4AM3 A;  2HH2 A;  2CTL A;  2ANR A;  1J5K A;  1X4M A;  2OPU A;  4AIM A;  1ZZJ A;  2PQU A;  1TUA A;  1EC6 A;  4BA2 I;  2CTM A;  2BA0 A;  1X4N A;  2HH3 A;  2BL5 A;  2AXY A;  4LIJ A;  2JA9 A;  5K36 G;  4JVH A;  2CTJ A;  2YQR A;  1ZZI A;  3AEV B;  2OPV A;  4BA1 I;  4IFD G;  2ANN A;  4QMF B;  2CTF A;  2QND A;  2MJH A;  2CTK A;  4WAL A;  2CPQ A;  2JEB I;  2JZX A;  4NBQ A;  2JVZ A;  4B8T A;  2P2R A;  2JEA I;  1WVN A;  4JVY A;  4WAN A;  1KHM A;  3V69 A;  2E3U A;  2PY9 A;  1K1G A;  2JE6 I;  1DTJ A;  2FMR A;  1VIH A;  1VIG A;  1DT4 A;  3VKE A; 
#chains in the Genus database with same CATH topology
 4FJU A;  1J4W A;  1ZTG A;  4LF5 H;  4K0K H;  2NN6 G;  1HNX H;  1N32 H;  2F4V H;  4EC5 A;  4NXN H;  1Z2I A;  4GKJ H;  5LMU H;  4LF9 H;  3OSS D;  1J5K A;  4AIM A;  1IBM H;  4KHP H;  4NZR M;  4JI3 H;  1X4N A;  1J5E H;  1UG8 A;  2AXY A;  2UUB H;  1S03 G;  4DR4 H;  3KDK A;  2VKC A;  4PDB A;  1V9N A;  4DV6 H;  5LL6 b;  2VQF H;  2CTF A;  2ANN A;  2CPM A;  4WAN A;  5A2Q W;  1K1G A;  3GKU A;  2JE6 I;  2FMR A;  5FLX W;  4DV7 H;  1I6U A;  1DT4 A;  1WHR A;  1N33 H;  1HNW H;  2FPH X;  1HR0 H;  4JI4 H;  4B3R H;  5JEA G;  4OO1 G;  4JI8 H;  3UOE A;  2UUA H;  4JI1 H;  1WE8 A;  2M8W A;  4OX9 H;  1SEI A;  4LFA H;  4JI0 H;  2FFM A;  4NZT M;  2CTL A;  1FJG H;  2VQE H;  4DV3 H;  4LFC H;  4X64 H;  1N34 H;  1ZZJ A;  4DR7 H;  5IWA H;  4G08 A;  2BA0 A;  4LIJ A;  4DUY H;  2CTJ A;  3AEV B;  4IFD G;  4OCH A;  5DT9 A;  4E9J A;  4YY3 H;  2CTK A;  4WAL A;  2JZX A;  2CWF A;  2CWH A;  4NBQ A;  4B8T A;  2JEA I;  1KHM A;  3RF2 A;  1FKA H;  3V69 A;  1NXU A;  1VBI A;  2PY9 A;  4JI5 H;  1VIH A;  1F0X A;  3I0P A;  3T1H H;  1MSZ A;  3VKE A;  2CTE A;  2G8Y A;  1IBK H;  1ZZK A;  4DR6 H;  3OET A;  3OTO H;  4DV4 H;  5C0X G;  3L7Z C;  2A1S A;  4OD6 A;  1ODH A;  4H8A A;  4NXM H;  4AM3 A;  2ZQE A;  2Y3M A;  2HH2 A;  1S20 A;  2HHH H;  2LTM A;  2X06 A;  4X66 H;  2PQU A;  3SB1 A;  1TUA A;  4DR2 H;  4JI7 H;  3KDG A;  2BL5 A;  1HNZ H;  4LFB H;  1PQX A;  2UXC H;  4FJS A;  5K36 G;  2YQR A;  1ZZI A;  4B3T H;  4LF6 H;  4BA1 I;  4DV2 H;  4LF8 H;  2E5L H;  2QND A;  2MJH A;  2UU9 H;  4JI6 H;  3J80 W;  2JEB I;  4DUZ H;  4JYA H;  1WVN A;  1X0A A;  3J81 W;  3T1Y H;  1DTJ A;  2LRR A;  1AN7 A;  1VIG A;  3GR5 A;  1V8C A;  4LF4 H;  2K1H A;  3JAM W;  3J7A K;  2PT7 G;  2UUC H;  4X62 H;  2LTL A;  3EZJ A;  2DGR A;  3NCV A;  1XMO H;  2Z0S A;  4GKK H;  4DV5 H;  2UXD H;  3U1K A;  4AQY H;  1I94 H;  4X65 H;  2ZM6 H;  2O4C A;  2ANR A;  4DR1 H;  3QD7 X;  5LMN H;  4DR5 H;  5IT9 W;  1XRH A;  1X4M A;  2OPU A;  5BR8 H;  4B3S H;  1EC6 A;  4BA2 I;  2CTM A;  2HH3 A;  3FAU A;  2JA9 A;  4JI2 H;  1N36 H;  1XNQ H;  2D9I A;  4JVH A;  2OPV A;  4B8C D;  3GAB A;  4QMF B;  4DR3 H;  2M6Q A;  1WTJ A;  2CPQ A;  2P2R A;  2JVZ A;  4DV0 H;  4DV1 H;  1XNR H;  4JVY A;  4B3M H;  1XMQ H;  2E3U A;  1IBL H;  2LF0 A;  4JV5 H;  1X9Z A;  4YHH H;  4LF7 H;  2UXB H; 
#chains in the Genus database with same CATH homology
 2CTE A;  1J4W A;  5JEA G;  1ZTG A;  4OO1 G;  2NN6 G;  1ZZK A;  2DGR A;  2Z0S A;  3L7Z C;  1WE8 A;  5C0X G;  3U1K A;  4AM3 A;  2HH2 A;  2CTL A;  2ANR A;  1J5K A;  1X4M A;  2OPU A;  4AIM A;  1ZZJ A;  2PQU A;  1TUA A;  1EC6 A;  4BA2 I;  2CTM A;  2BA0 A;  1X4N A;  2HH3 A;  2BL5 A;  2AXY A;  4LIJ A;  2JA9 A;  5K36 G;  4JVH A;  2CTJ A;  2YQR A;  1ZZI A;  3AEV B;  2OPV A;  4BA1 I;  4IFD G;  2ANN A;  4QMF B;  2CTF A;  2QND A;  2MJH A;  2CTK A;  4WAL A;  2CPQ A;  2JEB I;  2JZX A;  4NBQ A;  2JVZ A;  4B8T A;  2P2R A;  2JEA I;  1WVN A;  4JVY A;  4WAN A;  1KHM A;  3V69 A;  2E3U A;  2PY9 A;  1K1G A;  2JE6 I;  1DTJ A;  2FMR A;  1VIH A;  1VIG A;  1DT4 A;  3VKE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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