2R92E

Elongation complex of rna polymerase ii with artificial rdrp scaffold
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of RNA-dependent RNA polymerase II activity.
pubmed doi rcsb
molecule tags Transferase/rna
molecule keywords RNA (5'-R(*UP*GP*CP*AP*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3
total genus 50
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2007-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 2r92E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 2r92E02
2JA7E 4Y7NE 3GTJE 3HOXE 1I6HE 3S16E 4A3DE 3GTKE 2R93E 2B63E 3GTQE 3S1ME 1I3QE 3HOVE 4A3GE 2WB1H 4QIWH 5IYDE 5M3ME 4A3IE 3S1QE 2NVXE 4A3ME 1SFOE 3PO2E 4C3JE 2E2IE 4BY1E 5M5YE 2Y0SH 4C2ME 5C4JE 5IP9E 5IYBE 1WCME 1TWFE 5M3FE 2WAQH 3S1RE 4A3BE 2E2JE 2R92E 2JA5E 4C3HE 3I4NE 5IYCE 3CQZE 2NVQE 2PMZH 3M3YE 5FLME 4BY7E 1TWCE 3RZDE 1Y1VE 3S2HE 4A3FE 4BBRE 1K83E 3GTGE 4AYBH 3HOZE 4A3KE 2JA8E 4A3CE 3GTLE 5M5WE 1TWAE 4A3JE 3HOUE 2E2HE 5M5XE 3S15E 4C3IE 1DZFA 3S1NE 3S2DE 3H3VF 3HKZH 4BXXE 3FKIE 1Y1WE 5C4XE 2JA6E 3PO3E 1TWHE 4X6AE 1TWGE 2YU9E 2NVTE 3GTPE 3HOYE 4BBSE 2R7ZE 3HOWE 3S14E 1I50E 3GTME 3M4OE 3GTOE 2VUME 3K7AE 3S17E 4A3EE 3I4ME 3H0GE 5IP7E 3RZOE 4Y52E 4A3LE 5C3EE 1EIKA 5FJ8E 4A93E 5C44E 2NVYE 1R9TE
chains in the Genus database with same CATH superfamily
3HOVF 2JA7E 4JK1E 2JA5F 1K83F 4Y7NE 3GTJE 3HOXE 5C4JF 1I6HE 1R9TF 3S16E 2O5IE 1SMYE 2CW0E 4G7ZE 4A3DE 3GTKE 2R93E 4LLGE 4Q4ZE 5C4XF 3S1NF 2B63E 3GTQE 4C3HF 3I4NF 4A3GF 3S1ME 1I3QE 2NVXF 4A3JF 3HOVE 4A3GE 2WB1H 4QIWH 2B63F 1I50F 1I3QF 2WB1I 2Y0SI 4A3IF 5IYDE 5M3ME 2KRXA 4LK0E 5C44F 4OIPE 5M3FF 3S16F 4A3DF 4A3IE 4A3CF 2JA7F 3S1QE 2R92F 4C3IF 4OINE 2NVXE 4A3ME 1SFOE 4LK1E 5E17E 4XSXE 3EQLE 3GTKF 2R93F 1IW7E 1TWCF 4G7OE 3PO2E 4A3LF 4C3JE 5FJ8F 3HOXF 4A93F 3M3YF 2NVTF 4XLNE 2E2IE 2VUMF 3S17F 3GTGF 4A3KF 4BY1E 5M5YE 4LJZE 2JA8F 5IP9F 3RZDF 2Y0SH 4XSZE 3S2HF 1QKLA 3H0GF 4C2ME 5C4JE 5IP9E 3H3VG 5IYBE 1WCME 3K7AF 3HOYF 4A3BF 1TWFE 3GTQF 5M3FE 2WAQH 4A3FF 3S1RE 4MQ9E 1HQME 5IP7F 4A3BE 2E2JE 3GTPF 2R92E 2A6EE 4BY7F 2A68E 3S1QF 5IYBF 2PMZK 4AYBK 2JA5E 4C3HE 3I4NE 5IYCE 3GTMF 3CQZE 2NVQE 4KN7E 4MEXE 3HOZF 2PMZH 3S2DF 5IYCF 4BBSF 1I6VE 3M3YE 3GTLF 5FLME 5M5XF 5C3EF 4BY7E 2JA6F 3PO3F 4X6AF 1TWCE 3RZDE 3HKZK 2A6HE 1Y1VE 4Y52F 5D4CE 3S2HE 4A3FE 4BBRE 3HOWF 2R7ZF 4BXXF 4QIWK 5M5WF 1K83E 3GTGE 4AYBH 5E18E 1YNJK 4G7HE 4KMUE 2PPBE 5D4EE 3FKIF 3HOZE 3CQZF 4YG2E 4A3KE 2JA8E 1I6HF 4A3CE 3GTLE 5M5WE 1TWAE 4A3JE 2NVYF 2E2JF 4YFXE 4XLPE 2NVQF 3HOUE 2E2HE 4YFNE 4BY1F 3RZOF 5M5XE 5FLMF 3S15E 4C3IE 1DZFA 5TMCE 4C3JF 2A69E 4A3EF 2YU9F 3S1NE 3S2DE 4KN4E 3H3VF 1Y1WF 3HKZH 4ZH4E 4BXXE 3FKIE 4BBRF 3M4OF 1Y1WE 5C4XE 1ZYRE 2JA6E 3PO3E 1TWHE 4X6AE 2BE5E 1TWGE 2YU9E 2NVTE 3GTPE 3HOYE 1WCMF 4Q5SE 4YFKE 3DXJE 4BBSE 2R7ZE 3HOWE 1TWHF 4OIQE 1TWFF 3HOUF 3S14E 1I50E 3GTME 3WODE 3M4OE 3GTOE 4A3MF 2VUME 3K7AE 3S17E 3S15F 4Y7NF 3S1MF 4A3EE 4GZYE 4MEYE 3GTOF 3PO2F 5BYHE 3I4ME 2E2HF 3H0GE 5IP7E 3S1RF 3RZOE 2O5JE 5M3MF 5IYDF 1SFOF 4Y52E 1Y1VF 2E2IF 4OIRE 3I4MF 3GTJF 2WAQK 5M5YF 5IPLE 1TWAF 5TMFE 4A3LE 5C3EE 1EIKA 5FJ8E 4A93E 4C2MF 4OIOE 1YNNK 5C44E 5D4DE 3S14F 2NVYE 1TWGF 1R9TE
chains in the Genus database with same CATH topology
2JA7E 4Y7NE 3GTJE 3HOXE 1I6HE 3S16E 4A3DE 3GTKE 2R93E 2B63E 3GTQE 3S1ME 1I3QE 3HOVE 4A3GE 2WB1H 4QIWH 5IYDE 5M3ME 4A3IE 3S1QE 2NVXE 4A3ME 1SFOE 3PO2E 4C3JE 2E2IE 4BY1E 5M5YE 2Y0SH 4C2ME 5C4JE 5IP9E 5IYBE 1WCME 1TWFE 5M3FE 2WAQH 3S1RE 4A3BE 2E2JE 2R92E 2JA5E 4C3HE 3I4NE 5IYCE 3CQZE 2NVQE 2PMZH 3M3YE 5FLME 4BY7E 1TWCE 3RZDE 1Y1VE 3S2HE 4A3FE 4BBRE 1K83E 3GTGE 4AYBH 3HOZE 4A3KE 2JA8E 4A3CE 3GTLE 5M5WE 1TWAE 4A3JE 3HOUE 2E2HE 5M5XE 3S15E 4C3IE 1DZFA 3S1NE 3S2DE 3H3VF 3HKZH 4BXXE 3FKIE 1Y1WE 5C4XE 2JA6E 3PO3E 1TWHE 4X6AE 1TWGE 2YU9E 2NVTE 3GTPE 3HOYE 4BBSE 2R7ZE 3HOWE 3S14E 1I50E 3GTME 3M4OE 3GTOE 2VUME 3K7AE 3S17E 4A3EE 3I4ME 3H0GE 5IP7E 3RZOE 4Y52E 4A3LE 5C3EE 1EIKA 5FJ8E 4A93E 5C44E 2NVYE 1R9TE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JA7 E;  4Y7N E;  3GTJ E;  3HOX E;  1I6H E;  3S16 E;  4A3D E;  3GTK E;  2R93 E;  2B63 E;  3GTQ E;  3S1M E;  1I3Q E;  3HOV E;  4A3G E;  2WB1 H;  4QIW H;  5IYD E;  5M3M E;  4A3I E;  3S1Q E;  2NVX E;  4A3M E;  1SFO E;  3PO2 E;  4C3J E;  2E2I E;  4BY1 E;  5M5Y E;  2Y0S H;  4C2M E;  5C4J E;  5IP9 E;  5IYB E;  1WCM E;  1TWF E;  5M3F E;  2WAQ H;  3S1R E;  4A3B E;  2E2J E;  2R92 E;  2JA5 E;  4C3H E;  3I4N E;  5IYC E;  3CQZ E;  2NVQ E;  2PMZ H;  3M3Y E;  5FLM E;  4BY7 E;  1TWC E;  3RZD E;  1Y1V E;  3S2H E;  4A3F E;  4BBR E;  1K83 E;  3GTG E;  4AYB H;  3HOZ E;  4A3K E;  2JA8 E;  4A3C E;  3GTL E;  5M5W E;  1TWA E;  4A3J E;  3HOU E;  2E2H E;  5M5X E;  3S15 E;  4C3I E;  1DZF A;  3S1N E;  3S2D E;  3H3V F;  3HKZ H;  4BXX E;  3FKI E;  1Y1W E;  5C4X E;  2JA6 E;  3PO3 E;  1TWH E;  4X6A E;  1TWG E;  2YU9 E;  2NVT E;  3GTP E;  3HOY E;  4BBS E;  2R7Z E;  3HOW E;  3S14 E;  1I50 E;  3GTM E;  3M4O E;  3GTO E;  2VUM E;  3K7A E;  3S17 E;  4A3E E;  3I4M E;  3H0G E;  5IP7 E;  3RZO E;  4Y52 E;  4A3L E;  5C3E E;  1EIK A;  5FJ8 E;  4A93 E;  5C44 E;  2NVY E;  1R9T E; 
#chains in the Genus database with same CATH topology
 3HOV F;  2JA7 E;  4JK1 E;  2JA5 F;  1K83 F;  4Y7N E;  3GTJ E;  3HOX E;  5C4J F;  1I6H E;  1R9T F;  3S16 E;  2O5I E;  1SMY E;  2CW0 E;  4G7Z E;  4A3D E;  3GTK E;  2R93 E;  4LLG E;  4Q4Z E;  5C4X F;  3S1N F;  2B63 E;  3GTQ E;  4C3H F;  3I4N F;  4A3G F;  3S1M E;  1I3Q E;  2NVX F;  4A3J F;  3HOV E;  4A3G E;  2WB1 H;  4QIW H;  2B63 F;  1I50 F;  1I3Q F;  2WB1 I;  2Y0S I;  4A3I F;  5IYD E;  5M3M E;  2KRX A;  4LK0 E;  5C44 F;  4OIP E;  5M3F F;  3S16 F;  4A3D F;  4A3I E;  4A3C F;  2JA7 F;  3S1Q E;  2R92 F;  4C3I F;  4OIN E;  2NVX E;  4A3M E;  1SFO E;  4LK1 E;  5E17 E;  4XSX E;  3EQL E;  3GTK F;  2R93 F;  1IW7 E;  1TWC F;  4G7O E;  3PO2 E;  4A3L F;  4C3J E;  5FJ8 F;  3HOX F;  4A93 F;  3M3Y F;  2NVT F;  4XLN E;  2E2I E;  2VUM F;  3S17 F;  3GTG F;  4A3K F;  4BY1 E;  5M5Y E;  4LJZ E;  2JA8 F;  5IP9 F;  3RZD F;  2Y0S H;  4XSZ E;  3S2H F;  1QKL A;  3H0G F;  4C2M E;  5C4J E;  5IP9 E;  3H3V G;  5IYB E;  1WCM E;  3K7A F;  3HOY F;  4A3B F;  1TWF E;  3GTQ F;  5M3F E;  2WAQ H;  4A3F F;  3S1R E;  4MQ9 E;  1HQM E;  5IP7 F;  4A3B E;  2E2J E;  3GTP F;  2R92 E;  2A6E E;  4BY7 F;  2A68 E;  3S1Q F;  5IYB F;  2PMZ K;  4AYB K;  2JA5 E;  4C3H E;  3I4N E;  5IYC E;  3GTM F;  3CQZ E;  2NVQ E;  4KN7 E;  4MEX E;  3HOZ F;  2PMZ H;  3S2D F;  5IYC F;  4BBS F;  1I6V E;  3M3Y E;  3GTL F;  5FLM E;  5M5X F;  5C3E F;  4BY7 E;  2JA6 F;  3PO3 F;  4X6A F;  1TWC E;  3RZD E;  3HKZ K;  2A6H E;  1Y1V E;  4Y52 F;  5D4C E;  3S2H E;  4A3F E;  4BBR E;  3HOW F;  2R7Z F;  4BXX F;  4QIW K;  5M5W F;  1K83 E;  3GTG E;  4AYB H;  5E18 E;  1YNJ K;  4G7H E;  4KMU E;  2PPB E;  5D4E E;  3FKI F;  3HOZ E;  3CQZ F;  4YG2 E;  4A3K E;  2JA8 E;  1I6H F;  4A3C E;  3GTL E;  5M5W E;  1TWA E;  4A3J E;  2NVY F;  2E2J F;  4YFX E;  4XLP E;  2NVQ F;  3HOU E;  2E2H E;  4YFN E;  4BY1 F;  3RZO F;  5M5X E;  5FLM F;  3S15 E;  4C3I E;  1DZF A;  5TMC E;  4C3J F;  2A69 E;  4A3E F;  2YU9 F;  3S1N E;  3S2D E;  4KN4 E;  3H3V F;  1Y1W F;  3HKZ H;  4ZH4 E;  4BXX E;  3FKI E;  4BBR F;  3M4O F;  1Y1W E;  5C4X E;  1ZYR E;  2JA6 E;  3PO3 E;  1TWH E;  4X6A E;  2BE5 E;  1TWG E;  2YU9 E;  2NVT E;  3GTP E;  3HOY E;  1WCM F;  4Q5S E;  4YFK E;  3DXJ E;  4BBS E;  2R7Z E;  3HOW E;  1TWH F;  4OIQ E;  1TWF F;  3HOU F;  3S14 E;  1I50 E;  3GTM E;  3WOD E;  3M4O E;  3GTO E;  4A3M F;  2VUM E;  3K7A E;  3S17 E;  3S15 F;  4Y7N F;  3S1M F;  4A3E E;  4GZY E;  4MEY E;  3GTO F;  3PO2 F;  5BYH E;  3I4M E;  2E2H F;  3H0G E;  5IP7 E;  3S1R F;  3RZO E;  2O5J E;  5M3M F;  5IYD F;  1SFO F;  4Y52 E;  1Y1V F;  2E2I F;  4OIR E;  3I4M F;  3GTJ F;  2WAQ K;  5M5Y F;  5IPL E;  1TWA F;  5TMF E;  4A3L E;  5C3E E;  1EIK A;  5FJ8 E;  4A93 E;  4C2M F;  4OIO E;  1YNN K;  5C44 E;  5D4D E;  3S14 F;  2NVY E;  1TWG F;  1R9T E; 
#chains in the Genus database with same CATH homology
 2JA7 E;  4Y7N E;  3GTJ E;  3HOX E;  1I6H E;  3S16 E;  4A3D E;  3GTK E;  2R93 E;  2B63 E;  3GTQ E;  3S1M E;  1I3Q E;  3HOV E;  4A3G E;  2WB1 H;  4QIW H;  5IYD E;  5M3M E;  4A3I E;  3S1Q E;  2NVX E;  4A3M E;  1SFO E;  3PO2 E;  4C3J E;  2E2I E;  4BY1 E;  5M5Y E;  2Y0S H;  4C2M E;  5C4J E;  5IP9 E;  5IYB E;  1WCM E;  1TWF E;  5M3F E;  2WAQ H;  3S1R E;  4A3B E;  2E2J E;  2R92 E;  2JA5 E;  4C3H E;  3I4N E;  5IYC E;  3CQZ E;  2NVQ E;  2PMZ H;  3M3Y E;  5FLM E;  4BY7 E;  1TWC E;  3RZD E;  1Y1V E;  3S2H E;  4A3F E;  4BBR E;  1K83 E;  3GTG E;  4AYB H;  3HOZ E;  4A3K E;  2JA8 E;  4A3C E;  3GTL E;  5M5W E;  1TWA E;  4A3J E;  3HOU E;  2E2H E;  5M5X E;  3S15 E;  4C3I E;  1DZF A;  3S1N E;  3S2D E;  3H3V F;  3HKZ H;  4BXX E;  3FKI E;  1Y1W E;  5C4X E;  2JA6 E;  3PO3 E;  1TWH E;  4X6A E;  1TWG E;  2YU9 E;  2NVT E;  3GTP E;  3HOY E;  4BBS E;  2R7Z E;  3HOW E;  3S14 E;  1I50 E;  3GTM E;  3M4O E;  3GTO E;  2VUM E;  3K7A E;  3S17 E;  4A3E E;  3I4M E;  3H0G E;  5IP7 E;  3RZO E;  4Y52 E;  4A3L E;  5C3E E;  1EIK A;  5FJ8 E;  4A93 E;  5C44 E;  2NVY E;  1R9T E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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