2V3XA

His243ala escherichia coli aminopeptidase p in complex with substrate
Total Genus 159
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
159
sequence length
440
structure length
439
Chain Sequence
SEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILAYTENEEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords XAA-PRO AMINOPEPTIDASE
publication title Complexes of Mutants of Escherichia Coli Aminopeptidase P and the Tripeptide Substrate Valproleu.
pubmed doi rcsb
source organism Escherichia coli
total genus 159
structure length 439
sequence length 440
ec nomenclature ec 3.4.11.9: Xaa-Pro aminopeptidase.
pdb deposition date 2007-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF05195 AMP_N Aminopeptidase P, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 2v3xA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2v3xA02
1Y1NA 2Q95A 2DFIA 2BH3A 2GU7A 2GG5A 2EVOA 4S2TP 4U6WA 2Q92A 1QXZA 1R5HA 1XNZA 2GG7A 4U69A 2HOWA 3PN9A 4IKRA 4OOKA 4FLKA 2GGBA 4KM3A 2BWUA 3CTZA 1C27A 2Q93A 2GG0A 4U6CA 1R58A 3IG4A 3PKEA 2BWVA 1QZYA 1YVMA 5JFRA 1WLRA 2P98A 5D6FA 2BHBA 2P99A 2NQ7A 1YJ3A 4JUQA 2MATA 4PNCA 2B3HA 2V6CA 3BITA 3S6BA 3IL0A 3MR1A 1PV9A 4IU6A 2GGCA 4A6WA 1W7VA 1KP0A 1C22A 4S2RP 2EA2A 2EVCA 2BWXA 4U76A 2GU5A 5CDLA 1QXYA 2GTXA 4MATA 4RZZA 3BIPA 2EA4A 5CE6A 4ZWPA 1XGNA 1WN1A 3L24A 3BIQA 4FUKA 5CLSA 5JHUA 2BWSA 4FLIA 3FMQA 4FO8A 4ZWOA 2GG3A 2IW2A 2BHAA 1KQ0A 1C23A 5CIKA 4A6VA 1WL6A 2OAZA 4S01A 1WKMA 3IU8A 2NQ6A 3D27A 2Q96A 1O0XA 4PV4A 1KQ9A 3TAVA 2GZ5A 2GG9A 1W2MA 1XGSA 1XGMA 2BWWA 4FO7A 2BHCA 3TB5A 2Q8KA 4FKCA 1BOAA 3PKBA 4U6JA 2Q94A 3L7GA 1MATA 1R5GA 1YW9A 4U6ZA 5D6EA 4S00A 1YW8A 2BB7A 5CDEA 2OKNA 4B28A 2GA2A 1N51A 1B59A 1A16A 4FLLA 2GU4A 4U73A 2P9AA 5FCFA 5JI6A 4RZYA 4IKTA 4IKUA 4ZWUA 2GG2A 4U70A 5E5BA 2B3KA 4IKSA 2V3ZA 5CDVA 3O5VA 2EVMA 3PKCA 4U1BA 3Q6DA 2ZSGA 4U71A 5E2CA 4U75A 2BWTA 4HXXA 3PEBA 3MATA 3CB5A 3PKDA 3RORA 1M35A 2V3YA 4EGEA 3MX6A 4RGZ1 2GG8A 5FCHA 3PKAA 1WBQA 2BWYA 4QR8A 3IU9A 3FM3A 1C24A 5CNXA 1YW7A 1B6AA 4R60A 2GU6A 1XGOA 1JAWA 2BHDA 3OOOA 3CB6A 4IPAA 1BN5A 4IDYA 3OVKA 4IF7A 3I7MA 3RVAA 4ZNGA 1WY2A 2B3LA 2ADUA 2V3XA 4FLJA 2G6PA 1CHMA 4IECA 4U6EA 3FMRA 1C21A 1QXWA 3IU7A 1WL9A 3QOCA 2BN7A 4Z7MA
chains in the Genus database with same CATH superfamily
1Y1NA 2Q95A 2DFIA 2BH3A 2GU7A 2GG5A 2EVOA 4S2TP 4U6WA 2Q92A 1QXZA 1R5HA 1XNZA 2GG7A 4U69A 2HOWA 3PN9A 4IKRA 4OOKA 4FLKA 2GGBA 4KM3A 2BWUA 3CTZA 1C27A 2Q93A 2GG0A 4U6CA 1R58A 3IG4A 3PKEA 2BWVA 1QZYA 1YVMA 5JFRA 1WLRA 2P98A 5D6FA 2BHBA 2P99A 2NQ7A 1YJ3A 4JUQA 2MATA 4PNCA 2B3HA 2V6CA 3BITA 3S6BA 3IL0A 3MR1A 1PV9A 4IU6A 2GGCA 4A6WA 1W7VA 1KP0A 1C22A 4S2RP 2EA2A 2EVCA 2BWXA 4U76A 2GU5A 5CDLA 1QXYA 2GTXA 4MATA 4RZZA 3BIPA 2EA4A 5CE6A 4ZWPA 1XGNA 1WN1A 3L24A 3BIQA 4FUKA 5CLSA 5JHUA 2BWSA 4FLIA 3FMQA 4FO8A 4ZWOA 2GG3A 2IW2A 2BHAA 1KQ0A 1C23A 5CIKA 4A6VA 1WL6A 2OAZA 4S01A 1WKMA 3IU8A 2NQ6A 3D27A 2Q96A 1O0XA 4PV4A 1KQ9A 3TAVA 2GZ5A 2GG9A 1W2MA 1XGSA 1XGMA 2BWWA 4FO7A 2BHCA 3TB5A 2Q8KA 4FKCA 1BOAA 3PKBA 4U6JA 2Q94A 3L7GA 1MATA 1R5GA 1YW9A 4U6ZA 5D6EA 4S00A 1YW8A 2BB7A 5CDEA 2OKNA 4B28A 2GA2A 1N51A 1B59A 1A16A 4FLLA 2GU4A 4U73A 2P9AA 5FCFA 5JI6A 4RZYA 4IKTA 4IKUA 4ZWUA 2GG2A 4U70A 5E5BA 2B3KA 4IKSA 2V3ZA 5CDVA 3O5VA 2EVMA 3PKCA 4U1BA 3Q6DA 2ZSGA 4U71A 5E2CA 4U75A 2BWTA 4HXXA 3PEBA 3MATA 3CB5A 3PKDA 3RORA 1M35A 2V3YA 4EGEA 3MX6A 4RGZ1 2GG8A 5FCHA 3PKAA 1WBQA 2BWYA 4QR8A 3IU9A 3FM3A 1C24A 5CNXA 1YW7A 1B6AA 4R60A 2GU6A 1XGOA 1JAWA 2BHDA 3OOOA 3CB6A 4IPAA 1BN5A 4IDYA 3OVKA 4IF7A 3I7MA 3RVAA 4ZNGA 1WY2A 2B3LA 2ADUA 2V3XA 4FLJA 2G6PA 1CHMA 4IECA 4U6EA 3FMRA 1C21A 1QXWA 3IU7A 1WL9A 3QOCA 2BN7A 4Z7MA
chains in the Genus database with same CATH topology
1Y1NA 2Q95A 2DFIA 2BH3A 2GU7A 2GG5A 2EVOA 4S2TP 4U6WA 2Q92A 1QXZA 1R5HA 1XNZA 2GG7A 4U69A 2HOWA 3PN9A 4IKRA 4OOKA 4FLKA 2GGBA 4KM3A 2BWUA 3CTZA 1C27A 2Q93A 2GG0A 4U6CA 1R58A 3IG4A 3PKEA 2BWVA 1QZYA 1YVMA 5JFRA 1WLRA 2P98A 5D6FA 2BHBA 2P99A 2NQ7A 1YJ3A 4JUQA 2MATA 4PNCA 2B3HA 2V6CA 3BITA 3S6BA 3IL0A 3MR1A 1PV9A 4IU6A 2GGCA 4A6WA 1W7VA 1KP0A 1C22A 4S2RP 2EA2A 2EVCA 2BWXA 4U76A 2GU5A 5CDLA 1QXYA 2GTXA 4MATA 4RZZA 3BIPA 2EA4A 5CE6A 4ZWPA 1XGNA 1WN1A 3L24A 3BIQA 4FUKA 5CLSA 5JHUA 2BWSA 4FLIA 3FMQA 4FO8A 4ZWOA 2GG3A 2IW2A 2BHAA 1KQ0A 1C23A 5CIKA 4A6VA 1WL6A 2OAZA 4S01A 1WKMA 3IU8A 2NQ6A 3D27A 2Q96A 1O0XA 4PV4A 1KQ9A 3TAVA 2GZ5A 2GG9A 1W2MA 1XGSA 1XGMA 2BWWA 4FO7A 2BHCA 3TB5A 2Q8KA 4FKCA 1BOAA 3PKBA 4U6JA 2Q94A 3L7GA 1MATA 1R5GA 1YW9A 4U6ZA 5D6EA 4S00A 1YW8A 2BB7A 5CDEA 2OKNA 4B28A 2GA2A 1N51A 1B59A 1A16A 4FLLA 2GU4A 4U73A 2P9AA 5FCFA 5JI6A 4RZYA 4IKTA 4IKUA 4ZWUA 2GG2A 4U70A 5E5BA 2B3KA 4IKSA 2V3ZA 5CDVA 3O5VA 2EVMA 3PKCA 4U1BA 3Q6DA 2ZSGA 4U71A 5E2CA 4U75A 2BWTA 4HXXA 3PEBA 3MATA 3CB5A 3PKDA 3RORA 1M35A 2V3YA 4EGEA 3MX6A 4RGZ1 2GG8A 5FCHA 3PKAA 1WBQA 2BWYA 4QR8A 3IU9A 3FM3A 1C24A 5CNXA 1YW7A 1B6AA 4R60A 2GU6A 1XGOA 1JAWA 2BHDA 3OOOA 3CB6A 4IPAA 1BN5A 4IDYA 3OVKA 4IF7A 3I7MA 3RVAA 4ZNGA 1WY2A 2B3LA 2ADUA 2V3XA 4FLJA 2G6PA 1CHMA 4IECA 4U6EA 3FMRA 1C21A 1QXWA 3IU7A 1WL9A 3QOCA 2BN7A 4Z7MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y1N A;  2Q95 A;  2DFI A;  2BH3 A;  2GU7 A;  2GG5 A;  2EVO A;  4S2T P;  4U6W A;  2Q92 A;  1QXZ A;  1R5H A;  1XNZ A;  2GG7 A;  4U69 A;  2HOW A;  3PN9 A;  4IKR A;  4OOK A;  4FLK A;  2GGB A;  4KM3 A;  2BWU A;  3CTZ A;  1C27 A;  2Q93 A;  2GG0 A;  4U6C A;  1R58 A;  3IG4 A;  3PKE A;  2BWV A;  1QZY A;  1YVM A;  5JFR A;  1WLR A;  2P98 A;  5D6F A;  2BHB A;  2P99 A;  2NQ7 A;  1YJ3 A;  4JUQ A;  2MAT A;  4PNC A;  2B3H A;  2V6C A;  3BIT A;  3S6B A;  3IL0 A;  3MR1 A;  1PV9 A;  4IU6 A;  2GGC A;  4A6W A;  1W7V A;  1KP0 A;  1C22 A;  4S2R P;  2EA2 A;  2EVC A;  2BWX A;  4U76 A;  2GU5 A;  5CDL A;  1QXY A;  2GTX A;  4MAT A;  4RZZ A;  3BIP A;  2EA4 A;  5CE6 A;  4ZWP A;  1XGN A;  1WN1 A;  3L24 A;  3BIQ A;  4FUK A;  5CLS A;  5JHU A;  2BWS A;  4FLI A;  3FMQ A;  4FO8 A;  4ZWO A;  2GG3 A;  2IW2 A;  2BHA A;  1KQ0 A;  1C23 A;  5CIK A;  4A6V A;  1WL6 A;  2OAZ A;  4S01 A;  1WKM A;  3IU8 A;  2NQ6 A;  3D27 A;  2Q96 A;  1O0X A;  4PV4 A;  1KQ9 A;  3TAV A;  2GZ5 A;  2GG9 A;  1W2M A;  1XGS A;  1XGM A;  2BWW A;  4FO7 A;  2BHC A;  3TB5 A;  2Q8K A;  4FKC A;  1BOA A;  3PKB A;  4U6J A;  2Q94 A;  3L7G A;  1MAT A;  1R5G A;  1YW9 A;  4U6Z A;  5D6E A;  4S00 A;  1YW8 A;  2BB7 A;  5CDE A;  2OKN A;  4B28 A;  2GA2 A;  1N51 A;  1B59 A;  1A16 A;  4FLL A;  2GU4 A;  4U73 A;  2P9A A;  5FCF A;  5JI6 A;  4RZY A;  4IKT A;  4IKU A;  4ZWU A;  2GG2 A;  4U70 A;  5E5B A;  2B3K A;  4IKS A;  2V3Z A;  5CDV A;  3O5V A;  2EVM A;  3PKC A;  4U1B A;  3Q6D A;  2ZSG A;  4U71 A;  5E2C A;  4U75 A;  2BWT A;  4HXX A;  3PEB A;  3MAT A;  3CB5 A;  3PKD A;  3ROR A;  1M35 A;  2V3Y A;  4EGE A;  3MX6 A;  4RGZ 1;  2GG8 A;  5FCH A;  3PKA A;  1WBQ A;  2BWY A;  4QR8 A;  3IU9 A;  3FM3 A;  1C24 A;  5CNX A;  1YW7 A;  1B6A A;  4R60 A;  2GU6 A;  1XGO A;  1JAW A;  2BHD A;  3OOO A;  3CB6 A;  4IPA A;  1BN5 A;  4IDY A;  3OVK A;  4IF7 A;  3I7M A;  3RVA A;  4ZNG A;  1WY2 A;  2B3L A;  2ADU A;  2V3X A;  4FLJ A;  2G6P A;  1CHM A;  4IEC A;  4U6E A;  3FMR A;  1C21 A;  1QXW A;  3IU7 A;  1WL9 A;  3QOC A;  2BN7 A;  4Z7M A; 
#chains in the Genus database with same CATH topology
 1Y1N A;  2Q95 A;  2DFI A;  2BH3 A;  2GU7 A;  2GG5 A;  2EVO A;  4S2T P;  4U6W A;  2Q92 A;  1QXZ A;  1R5H A;  1XNZ A;  2GG7 A;  4U69 A;  2HOW A;  3PN9 A;  4IKR A;  4OOK A;  4FLK A;  2GGB A;  4KM3 A;  2BWU A;  3CTZ A;  1C27 A;  2Q93 A;  2GG0 A;  4U6C A;  1R58 A;  3IG4 A;  3PKE A;  2BWV A;  1QZY A;  1YVM A;  5JFR A;  1WLR A;  2P98 A;  5D6F A;  2BHB A;  2P99 A;  2NQ7 A;  1YJ3 A;  4JUQ A;  2MAT A;  4PNC A;  2B3H A;  2V6C A;  3BIT A;  3S6B A;  3IL0 A;  3MR1 A;  1PV9 A;  4IU6 A;  2GGC A;  4A6W A;  1W7V A;  1KP0 A;  1C22 A;  4S2R P;  2EA2 A;  2EVC A;  2BWX A;  4U76 A;  2GU5 A;  5CDL A;  1QXY A;  2GTX A;  4MAT A;  4RZZ A;  3BIP A;  2EA4 A;  5CE6 A;  4ZWP A;  1XGN A;  1WN1 A;  3L24 A;  3BIQ A;  4FUK A;  5CLS A;  5JHU A;  2BWS A;  4FLI A;  3FMQ A;  4FO8 A;  4ZWO A;  2GG3 A;  2IW2 A;  2BHA A;  1KQ0 A;  1C23 A;  5CIK A;  4A6V A;  1WL6 A;  2OAZ A;  4S01 A;  1WKM A;  3IU8 A;  2NQ6 A;  3D27 A;  2Q96 A;  1O0X A;  4PV4 A;  1KQ9 A;  3TAV A;  2GZ5 A;  2GG9 A;  1W2M A;  1XGS A;  1XGM A;  2BWW A;  4FO7 A;  2BHC A;  3TB5 A;  2Q8K A;  4FKC A;  1BOA A;  3PKB A;  4U6J A;  2Q94 A;  3L7G A;  1MAT A;  1R5G A;  1YW9 A;  4U6Z A;  5D6E A;  4S00 A;  1YW8 A;  2BB7 A;  5CDE A;  2OKN A;  4B28 A;  2GA2 A;  1N51 A;  1B59 A;  1A16 A;  4FLL A;  2GU4 A;  4U73 A;  2P9A A;  5FCF A;  5JI6 A;  4RZY A;  4IKT A;  4IKU A;  4ZWU A;  2GG2 A;  4U70 A;  5E5B A;  2B3K A;  4IKS A;  2V3Z A;  5CDV A;  3O5V A;  2EVM A;  3PKC A;  4U1B A;  3Q6D A;  2ZSG A;  4U71 A;  5E2C A;  4U75 A;  2BWT A;  4HXX A;  3PEB A;  3MAT A;  3CB5 A;  3PKD A;  3ROR A;  1M35 A;  2V3Y A;  4EGE A;  3MX6 A;  4RGZ 1;  2GG8 A;  5FCH A;  3PKA A;  1WBQ A;  2BWY A;  4QR8 A;  3IU9 A;  3FM3 A;  1C24 A;  5CNX A;  1YW7 A;  1B6A A;  4R60 A;  2GU6 A;  1XGO A;  1JAW A;  2BHD A;  3OOO A;  3CB6 A;  4IPA A;  1BN5 A;  4IDY A;  3OVK A;  4IF7 A;  3I7M A;  3RVA A;  4ZNG A;  1WY2 A;  2B3L A;  2ADU A;  2V3X A;  4FLJ A;  2G6P A;  1CHM A;  4IEC A;  4U6E A;  3FMR A;  1C21 A;  1QXW A;  3IU7 A;  1WL9 A;  3QOC A;  2BN7 A;  4Z7M A; 
#chains in the Genus database with same CATH homology
 1Y1N A;  2Q95 A;  2DFI A;  2BH3 A;  2GU7 A;  2GG5 A;  2EVO A;  4S2T P;  4U6W A;  2Q92 A;  1QXZ A;  1R5H A;  1XNZ A;  2GG7 A;  4U69 A;  2HOW A;  3PN9 A;  4IKR A;  4OOK A;  4FLK A;  2GGB A;  4KM3 A;  2BWU A;  3CTZ A;  1C27 A;  2Q93 A;  2GG0 A;  4U6C A;  1R58 A;  3IG4 A;  3PKE A;  2BWV A;  1QZY A;  1YVM A;  5JFR A;  1WLR A;  2P98 A;  5D6F A;  2BHB A;  2P99 A;  2NQ7 A;  1YJ3 A;  4JUQ A;  2MAT A;  4PNC A;  2B3H A;  2V6C A;  3BIT A;  3S6B A;  3IL0 A;  3MR1 A;  1PV9 A;  4IU6 A;  2GGC A;  4A6W A;  1W7V A;  1KP0 A;  1C22 A;  4S2R P;  2EA2 A;  2EVC A;  2BWX A;  4U76 A;  2GU5 A;  5CDL A;  1QXY A;  2GTX A;  4MAT A;  4RZZ A;  3BIP A;  2EA4 A;  5CE6 A;  4ZWP A;  1XGN A;  1WN1 A;  3L24 A;  3BIQ A;  4FUK A;  5CLS A;  5JHU A;  2BWS A;  4FLI A;  3FMQ A;  4FO8 A;  4ZWO A;  2GG3 A;  2IW2 A;  2BHA A;  1KQ0 A;  1C23 A;  5CIK A;  4A6V A;  1WL6 A;  2OAZ A;  4S01 A;  1WKM A;  3IU8 A;  2NQ6 A;  3D27 A;  2Q96 A;  1O0X A;  4PV4 A;  1KQ9 A;  3TAV A;  2GZ5 A;  2GG9 A;  1W2M A;  1XGS A;  1XGM A;  2BWW A;  4FO7 A;  2BHC A;  3TB5 A;  2Q8K A;  4FKC A;  1BOA A;  3PKB A;  4U6J A;  2Q94 A;  3L7G A;  1MAT A;  1R5G A;  1YW9 A;  4U6Z A;  5D6E A;  4S00 A;  1YW8 A;  2BB7 A;  5CDE A;  2OKN A;  4B28 A;  2GA2 A;  1N51 A;  1B59 A;  1A16 A;  4FLL A;  2GU4 A;  4U73 A;  2P9A A;  5FCF A;  5JI6 A;  4RZY A;  4IKT A;  4IKU A;  4ZWU A;  2GG2 A;  4U70 A;  5E5B A;  2B3K A;  4IKS A;  2V3Z A;  5CDV A;  3O5V A;  2EVM A;  3PKC A;  4U1B A;  3Q6D A;  2ZSG A;  4U71 A;  5E2C A;  4U75 A;  2BWT A;  4HXX A;  3PEB A;  3MAT A;  3CB5 A;  3PKD A;  3ROR A;  1M35 A;  2V3Y A;  4EGE A;  3MX6 A;  4RGZ 1;  2GG8 A;  5FCH A;  3PKA A;  1WBQ A;  2BWY A;  4QR8 A;  3IU9 A;  3FM3 A;  1C24 A;  5CNX A;  1YW7 A;  1B6A A;  4R60 A;  2GU6 A;  1XGO A;  1JAW A;  2BHD A;  3OOO A;  3CB6 A;  4IPA A;  1BN5 A;  4IDY A;  3OVK A;  4IF7 A;  3I7M A;  3RVA A;  4ZNG A;  1WY2 A;  2B3L A;  2ADU A;  2V3X A;  4FLJ A;  2G6P A;  1CHM A;  4IEC A;  4U6E A;  3FMR A;  1C21 A;  1QXW A;  3IU7 A;  1WL9 A;  3QOC A;  2BN7 A;  4Z7M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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