2VKIA

Structure of the pdk1 ph domain k465e mutant
Total Genus 39
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
139
structure length
139
Chain Sequence
SNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDERKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mutation of the Pdk1 Ph Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords 3-PHOPSHOINOSITIDE DEPENDENT PROTEIN KINASE 1
total genus 39
structure length 139
sequence length 139
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-12-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14593 PH_3 PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2vkiA00
2DKPA 4HAUB 5HE2A 4MY6A 2G35A 3CIKA 5LONB 1V5PA 2ADZA 3D8DA 4YONA 5L81A 2I5FA 4K17A 3DXEA 4HAYB 1WJ1A 3T06A 5J3YA 5D3XA 4Z2MB 2ELAA 2H7DA 1FOEA 4EKUA 1BWNA 3SUZA 2EC1A 1UNPA 1PMSA 2LKOA 2LULA 4CHJA 1XD4A 1E5WA 2ROVA 1V61A 2D11A 2X18A 4Y94A 1XR0B 1WJMA 1U5DA 2NZ8B 2H7EA 2CODA 2GS0A 1M7EA 4F7HA 2YS5A 2E2XA 1FHOA 4HDQA 2W2WA 3DXCA 1V88A 4C0AA 1MKEA 2D9XA 2EMSA 2YT0A 1I2HA 3PZDA 3TW1A 1GG3A 2RLOA 3AJ4A 4DX90 3NSUA 4L6EA 1J19A 3PVUA 1U2BA 4HB4B 1TQZA 4F7GA 2K00A 5DIFB 1Z87A 5D3VA 2Y8GA 4HDOA 2DLWA 2KUPA 1ZVRA 3P6AA 2ZPYA 1DBHA 5EFXA 2R09A 3MPXA 1MAIA 4A5KA 4HATB 2J0JA 1W1GA 3AU4A 4Z2NA 1LB1A 2P0HA 4KHBB 2DHJA 4ZRIA 1FHXA 2RNRB 1BAKA 4A6FA 2YS1A 5DHFB 2YVCA 4CHMA 5KQ1A 3KRWA 2P0DA 2NMBA 1IRSA 2VKIA 3SNHA 3GYPA 1BTNA 5FI1A 2OQBA 2YRYA 4A6FB 2PZ1A 2DYNA 3AU5A 4HHVA 2L2IA 2QKMA 1DDVA 1NI2A 1P3RA 2DYQA 3P7ZA 1UNRA 2Z0PA 4NSWA 2W2XC 2XQNM 2IYBA 4ZRKA 2DA0A 4H8SA 2MFQA 1TXDA 1NTVA 3O96A 3BJIA 1UPQA 3ODOA 5JHGA 4HB3B 3ODWA 2AL6A 1XCGA 1MIZB 2VSZA 2N23A 3DXDA 3A98B 1FHWA 4HAXB 2GJYA 1X05A 4K2PA 2I1JA 2N0YA 1FGZA 5JLJB 1TJ6A 4D0NB 3BINA 4WJ7A 3F5RA 1H4RA 4HB2B 1ZC4B 3A8PA 1QQGA 4EMOA 4CYEA 5KQ4A 3D8FA 2DX1A 2LYDA 5CLQB 5D3YA 2V76A 3TCAA 4K2OA 2J59M 4HB0B 2LG1A 4WSFA 4KHAA 1M7RA 2DHIA 4HAWB 5HE1A 2Q13A 2HE7A 4DXAB 2GCLA 1AWEA 1OY2A 2CY5A 4GPTB 2R0DA 3PG7A 2D9WA 3IVFA 2P0FA 2UZSA 1K5GB 2UZRA 2RUKB 3PEGA 1RRPB 2DX5A 2YT1A 2Z0OA 1EF1A 3WYFB 5J3TA 4DX8A 2RSGA 3F0WA 4HAVB 3U7DA 4NY0A 1X86A 2IFSA 3KSYA 1PLSA 1KZGA 1W1DA 1RJ2A 3D8EA 4WVFB 1EVHA 1KZ7A 3KRXA 2RGNB 1AQCA 2YSZA 4TKNA 4IFSA 3ML4A 3V5WA 2YF0A 4GN1A 1FB8A 1B55A 1EAZA 3QBVB 5KCVA 2LOZA 1GC7A 5JHHA 4F7UP 1Y19B 1W1HA 3WA0A 1ZC3B 2CY4A 2ROZB 1U5GA 3FSSA 1KI1B 2J0KA 4A6KA 3TFMA 5LOPB 2D10A 3LJUX 1WI1A 1P6SA 1DROA 3ODXA 3TO1A 2CRFA 3U8ZA 5FI0A 4KHOA 2D9YA 4GZUA 3ULCA 1LW3A 1XX0A 1WVHA 5DHAB 3M1IB 1UEFA 1FAOA 5C5BA 1WG7A 2RVBB 5HE3A 1PFJA 4XWXA 1X1GA 5HE0A 3MDBC 4ZRJA 1V89A 3N7CA 1SGHA 5C5BB 3VIAA 5C79A 2QKLA 2D2QA 2M38A 4GMVA 1MK7B 4IOYX 1NTYA 2CAYA 2LOXA 2DFKA 2P8VA 1N3HA 4DBBA 3CXBB 1ZSQA 5D3WA 1UNQA 1U27A 2VRWB 4B6HA 2COFA 4GXBA 2Y8FA 4GMXB 5J3QA 4P7IA 2BCJA 3ZDTA 1U5FA 2FJLA 5C6RA 1K5DB 2K2UA 1U29A 3FEHA 1FGYA 1X1FA 2HTHB 2J0MA 1J0WA 3PVLA 2Z0QA 5GOWB 1WGQA 5DH9B 3QWMA 2DTCA 2JP2A 2MWNB 4YL8A 1DDWA 2ELBA 3PP2A 3G9WA 1MPHA 3KY9A 4MK0A 3HK0A 1BTKA 3FM8C 2W2XD 2AEHA 1U5EA 3RCPA 3PVWA 4KAXB 4KVGB 4EJNA 1EGXA 4MT7A 2COAA 1OMWA 2M14A 3X23A 2DKQA 1I7AA 1NU2A 2D9VA 2KCJA 4TYZA 1P5TA 1SHCA 1X11A 2DN6A 3SYXA 5D27A 2I5CA 3TVVA 2UVMA 3HW2B 3OANA 2L1CA 1DDMA 3ZVRA 5C16A 2EJ8A 3SV1A 3SO6A 2MDXA 1ZM0A 2YS3A 1V5MA 2K2JA 1GC6A 5CLLB 4BBKA 2D9ZA 2Y7BA 1MK9B 1Y5OA 5JP4A 3A8QA 1DYNA 4PNKA 3PSCA 3UZTA 1QC6A 1MIXA 1V5UA 1OQNA 3VOQA 2OTXA 2COCA 4HAZB 2MKRA 4IAPA 1XKEA 3QIJA 2D4QA 4PQ0A 3KZ1A 4A6HA 2DHKA 3GYOA 5DI9B 3HQCA 1H10A 2EMTA 2GCJA 1WGUA 4K81A 3ULBA 1UPRA 1XODA 2I1KA 1ISNA 2KGXB 1Q67A
chains in the Genus database with same CATH superfamily
2DKPA 4HAUB 5HE2A 4MY6A 2G35A 3CIKA 5LONB 1V5PA 2ADZA 3D8DA 4YONA 5L81A 2I5FA 4K17A 3DXEA 4HAYB 3HSAA 1WJ1A 3T06A 5J3YA 5D3XA 4Z2MB 2ELAA 2KUQA 2H7DA 1FOEA 4EKUA 1BWNA 3SUZA 2EC1A 1UNPA 1PMSA 2LKOA 2RRFA 2LULA 4CHJA 1XD4A 1E5WA 2ROVA 1V61A 2D11A 2X18A 4Y94A 1XR0B 1WJMA 1U5DA 2NZ8B 2H7EA 2CODA 2GS0A 4QXAB 1M7EA 4F7HA 2YS5A 2E2XA 1FHOA 4HDQA 2W2WA 3DXCA 1V88A 4C0AA 1MKEA 2D9XA 2EMSA 2YT0A 1I2HA 3PZDA 3TW1A 1GG3A 2RLOA 3AJ4A 4DX90 3NSUA 4L6EA 1J19A 3PVUA 1U2BA 4HB4B 4QJ3B 1TQZA 4F7GA 2K00A 5DIFB 1Z87A 5D3VA 2Y8GA 4HDOA 2DLWA 2KUPA 1ZVRA 3P6AA 2ZPYA 4KHBA 1DBHA 3NW8A 5EFXA 2R09A 3MPXA 1MAIA 4A5KA 4HATB 2J0JA 1W1GA 3AU4A 4Z2NA 1LB1A 2P0HA 4KHBB 2DHJA 4ZRIA 1FHXA 2RNRB 1BAKA 4A6FA 2YS1A 1MI1A 5DHFB 2YVCA 4CHMA 5KQ1A 3KRWA 2P0DA 2NMBA 1IRSA 2VKIA 3SNHA 3GYPA 1BTNA 5FI1A 2OQBA 2YRYA 4A6FB 2PZ1A 2DYNA 3AU5A 4HHVA 2L2IA 2QKMA 1DDVA 1NI2A 1P3RA 2DYQA 3P7ZA 1UNRA 2Z0PA 3NWFA 4NSWA 2FJUB 2W2XC 4CSQA 2XQNM 2IYBA 4ZRKA 2DA0A 4H8SA 5I2MA 2MFQA 1TXDA 2GUMA 1NTVA 3O96A 2Z13A 3BJIA 1UPQA 3ODOA 5JHGA 4HB3B 3ODWA 2AL6A 4QJ5B 1XCGA 1MIZB 2VSZA 2N23A 3DXDA 2Z14A 2Z4DA 3A98B 1FHWA 4HAXB 2GJYA 1X05A 4K2PA 3HIEA 2I1JA 2N0YA 1FGZA 5JLJB 1TJ6A 4D0NB 3BINA 4WJ7A 3F5RA 1H4RA 4HB2B 4D6WA 1ZC4B 3OHMB 3A8PA 1QQGA 4EMOA 4CYEA 5KQ4A 3D8FA 2DX1A 2LYDA 5CLQB 5D3YA 2V76A 3NWAA 3TCAA 4K2OA 2J59M 4HB0B 2LG1A 4WSFA 4KHAA 1M7RA 2DHIA 4HAWB 5M4YB 2KR0A 5HE1A 2Q13A 2HE7A 4DXAB 2GCLA 3NWDA 1AWEA 1OY2A 2K8EA 2CY5A 4GPTB 2R0DA 3PG7A 4GOUA 2D9WA 3IVFA 5LG4B 2P0FA 2UZSA 1K5GB 2UZRA 2RUKB 3PEGA 1RRPB 2DX5A 2YT1A 2Z0OA 1EF1A 3WYFB 5J3TA 4DX8A 2RSGA 3F0WA 4HAVB 3U7DA 4NY0A 1X86A 2IFSA 3KSYA 1PLSA 1KZGA 1W1DA 1RJ2A 3D8EA 4WVFB 1EVHA 1KZ7A 3KRXA 2KIEA 2RGNB 1AQCA 2YSZA 4OT1A 4TKNA 4IFSA 3ML4A 3V5WA 3DCXA 2YF0A 4GN1A 1FB8A 1B55A 1EAZA 3QBVB 5KCVA 2LOZA 1GC7A 5JHHA 4F7UP 1Y19B 4L1RA 2Z59A 1W1HA 3WA0A 1ZC3B 2CY4A 2ROZB 1U5GA 3FSSA 1KI1B 4HSIA 2J0KA 4A6KA 3TFMA 5LOPB 2D10A 3LJUX 1WI1A 1P6SA 1DROA 3ODXA 3TO1A 2CRFA 3U8ZA 4QJ4B 5FI0A 4KHOA 2D9YA 4GZUA 3ULCA 1LW3A 1XX0A 1WVHA 5DHAB 2NBVA 3M1IB 1UEFA 1FAOA 5C5BA 1WG7A 2RVBB 5HE3A 1PFJA 4XWXA 1X1GA 5HE0A 3MDBC 4ZRJA 1V89A 3N7CA 1SGHA 5C5BB 3VIAA 5C79A 5I2SA 2QKLA 2D2QA 2M38A 4GMVA 1MK7B 4IOYX 1NTYA 2CAYA 2LOXA 2DFKA 2P8VA 1N3HA 1ZYIA 4DBBA 3CXBB 1ZSQA 5D3WA 1UNQA 1U27A 2VRWB 4B6HA 2COFA 4GXBA 2Y8FA 4GMXB 5J3QA 4P7IA 2BCJA 3B77A 3ZDTA 1U5FA 2FJLA 5C6RA 1K5DB 2K2UA 1U29A 3FEHA 1FGYA 1X1FA 2HTHB 2J0MA 1J0WA 3PVLA 2Z0QA 5GOWB 1WGQA 5DH9B 3QWMA 2DTCA 2JP2A 2MWNB 4YL8A 1DDWA 2ELBA 3PP2A 3G9WA 1MPHA 3KY9A 4MK0A 2KIGA 4OSNA 3HK0A 1BTKA 3FM8C 2W2XD 2AEHA 1U5EA 3RCPA 3PVWA 4KAXB 4KVGB 4EJNA 1EGXA 4MT7A 2COAA 1OMWA 2M14A 3X23A 2DKQA 1I7AA 3A58A 1NU2A 2D9VA 2KCJA 4TYZA 1P5TA 1SHCA 1X11A 4DIXA 2DN6A 3SYXA 5D27A 3U12A 2YT2A 2I5CA 3TVVA 2UVMA 3HW2B 3OANA 2R2YA 2L1CA 1DDMA 3ZVRA 5C16A 2EJ8A 3SV1A 3SO6A 2MDXA 1ZM0A 1T77A 2YS3A 1V5MA 2K2JA 1GC6A 5CLLB 4BBKA 2D9ZA 2Y7BA 1MK9B 1Y5OA 5JP4A 3A8QA 1DYNA 4PNKA 3PSCA 3UZTA 1QC6A 1MIXA 1V5UA 1OQNA 3VOQA 2OTXA 3FVCA 2ZKMX 2COCA 4HAZB 4GNKB 2MKRA 4IAPA 1XKEA 3QIJA 2D4QA 4PQ0A 3KZ1A 4A6HA 2DHKA 3GYOA 5DI9B 3HQCA 1H10A 2EMTA 2GCJA 1WGUA 4K81A 3ULBA 2K49A 5IRSA 1UPRA 1XODA 2I1KA 1ISNA 2KGXB 1Q67A
chains in the Genus database with same CATH topology
2DKPA 4HAUB 5HE2A 4MY6A 2G35A 3CIKA 5LONB 1V5PA 2ADZA 3D8DA 4YONA 5L81A 2I5FA 4K17A 3DXEA 4HAYB 1WJ1A 3T06A 5J3YA 5D3XA 4Z2MB 2ELAA 2H7DA 1FOEA 4EKUA 1BWNA 3SUZA 2EC1A 1UNPA 1PMSA 2LKOA 2LULA 4CHJA 1XD4A 1E5WA 2ROVA 1V61A 2D11A 2X18A 4Y94A 1XR0B 1WJMA 1U5DA 2NZ8B 2H7EA 2CODA 2GS0A 1M7EA 4F7HA 2YS5A 2E2XA 1FHOA 4HDQA 2W2WA 3DXCA 1V88A 4C0AA 1MKEA 2D9XA 2EMSA 2YT0A 1I2HA 3PZDA 3TW1A 1GG3A 2RLOA 3AJ4A 4DX90 3NSUA 4L6EA 1J19A 3PVUA 1U2BA 4HB4B 1TQZA 4F7GA 2K00A 5DIFB 1Z87A 5D3VA 2Y8GA 4HDOA 2DLWA 2KUPA 1ZVRA 3P6AA 2ZPYA 1DBHA 5EFXA 2R09A 3MPXA 1MAIA 4A5KA 4HATB 2J0JA 1W1GA 3AU4A 4Z2NA 1LB1A 2P0HA 4KHBB 2DHJA 4ZRIA 1FHXA 2RNRB 1BAKA 4A6FA 2YS1A 5DHFB 2YVCA 4CHMA 5KQ1A 3KRWA 2P0DA 2NMBA 1IRSA 2VKIA 3SNHA 3GYPA 1BTNA 5FI1A 2OQBA 2YRYA 4A6FB 2PZ1A 2DYNA 3AU5A 4HHVA 2L2IA 2QKMA 1DDVA 1NI2A 1P3RA 2DYQA 3P7ZA 1UNRA 2Z0PA 4NSWA 2W2XC 2XQNM 2IYBA 4ZRKA 2DA0A 4H8SA 2MFQA 1TXDA 1NTVA 3O96A 3BJIA 1UPQA 3ODOA 5JHGA 4HB3B 3ODWA 2AL6A 1XCGA 1MIZB 2VSZA 2N23A 3DXDA 3A98B 1FHWA 4HAXB 2GJYA 1X05A 4K2PA 2I1JA 2N0YA 1FGZA 5JLJB 1TJ6A 4D0NB 3BINA 4WJ7A 3F5RA 1H4RA 4HB2B 1ZC4B 3A8PA 1QQGA 4EMOA 4CYEA 5KQ4A 3D8FA 2DX1A 2LYDA 5CLQB 5D3YA 2V76A 3TCAA 4K2OA 2J59M 4HB0B 2LG1A 4WSFA 4KHAA 1M7RA 2DHIA 4HAWB 5HE1A 2Q13A 2HE7A 4DXAB 2GCLA 1AWEA 1OY2A 2CY5A 4GPTB 2R0DA 3PG7A 2D9WA 3IVFA 2P0FA 2UZSA 1K5GB 2UZRA 2RUKB 3PEGA 1RRPB 2DX5A 2YT1A 2Z0OA 1EF1A 3WYFB 5J3TA 4DX8A 2RSGA 3F0WA 4HAVB 3U7DA 4NY0A 1X86A 2IFSA 3KSYA 1PLSA 1KZGA 1W1DA 1RJ2A 3D8EA 4WVFB 1EVHA 1KZ7A 3KRXA 2RGNB 1AQCA 2YSZA 4TKNA 4IFSA 3ML4A 3V5WA 2YF0A 4GN1A 1FB8A 1B55A 1EAZA 3QBVB 5KCVA 2LOZA 1GC7A 5JHHA 4F7UP 1Y19B 1W1HA 3WA0A 1ZC3B 2CY4A 2ROZB 1U5GA 3FSSA 1KI1B 2J0KA 4A6KA 3TFMA 5LOPB 2D10A 3LJUX 1WI1A 1P6SA 1DROA 3ODXA 3TO1A 2CRFA 3U8ZA 5FI0A 4KHOA 2D9YA 4GZUA 3ULCA 1LW3A 1XX0A 1WVHA 5DHAB 3M1IB 1UEFA 1FAOA 5C5BA 1WG7A 2RVBB 5HE3A 1PFJA 4XWXA 1X1GA 5HE0A 3MDBC 4ZRJA 1V89A 3N7CA 1SGHA 5C5BB 3VIAA 5C79A 2QKLA 2D2QA 2M38A 4GMVA 1MK7B 4IOYX 1NTYA 2CAYA 2LOXA 2DFKA 2P8VA 1N3HA 4DBBA 3CXBB 1ZSQA 5D3WA 1UNQA 1U27A 2VRWB 4B6HA 2COFA 4GXBA 2Y8FA 4GMXB 5J3QA 4P7IA 2BCJA 3ZDTA 1U5FA 2FJLA 5C6RA 1K5DB 2K2UA 1U29A 3FEHA 1FGYA 1X1FA 2HTHB 2J0MA 1J0WA 3PVLA 2Z0QA 5GOWB 1WGQA 5DH9B 3QWMA 2DTCA 2JP2A 2MWNB 4YL8A 1DDWA 2ELBA 3PP2A 3G9WA 1MPHA 3KY9A 4MK0A 3HK0A 1BTKA 3FM8C 2W2XD 2AEHA 1U5EA 3RCPA 3PVWA 4KAXB 4KVGB 4EJNA 1EGXA 4MT7A 2COAA 1OMWA 2M14A 3X23A 2DKQA 1I7AA 1NU2A 2D9VA 2KCJA 4TYZA 1P5TA 1SHCA 1X11A 2DN6A 3SYXA 5D27A 2I5CA 3TVVA 2UVMA 3HW2B 3OANA 2L1CA 1DDMA 3ZVRA 5C16A 2EJ8A 3SV1A 3SO6A 2MDXA 1ZM0A 2YS3A 1V5MA 2K2JA 1GC6A 5CLLB 4BBKA 2D9ZA 2Y7BA 1MK9B 1Y5OA 5JP4A 3A8QA 1DYNA 4PNKA 3PSCA 3UZTA 1QC6A 1MIXA 1V5UA 1OQNA 3VOQA 2OTXA 2COCA 4HAZB 2MKRA 4IAPA 1XKEA 3QIJA 2D4QA 4PQ0A 3KZ1A 4A6HA 2DHKA 3GYOA 5DI9B 3HQCA 1H10A 2EMTA 2GCJA 1WGUA 4K81A 3ULBA 1UPRA 1XODA 2I1KA 1ISNA 2KGXB 1Q67A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DKP A;  4HAU B;  5HE2 A;  4MY6 A;  2G35 A;  3CIK A;  5LON B;  1V5P A;  2ADZ A;  3D8D A;  4YON A;  5L81 A;  2I5F A;  4K17 A;  3DXE A;  4HAY B;  1WJ1 A;  3T06 A;  5J3Y A;  5D3X A;  4Z2M B;  2ELA A;  2H7D A;  1FOE A;  4EKU A;  1BWN A;  3SUZ A;  2EC1 A;  1UNP A;  1PMS A;  2LKO A;  2LUL A;  4CHJ A;  1XD4 A;  1E5W A;  2ROV A;  1V61 A;  2D11 A;  2X18 A;  4Y94 A;  1XR0 B;  1WJM A;  1U5D A;  2NZ8 B;  2H7E A;  2COD A;  2GS0 A;  1M7E A;  4F7H A;  2YS5 A;  2E2X A;  1FHO A;  4HDQ A;  2W2W A;  3DXC A;  1V88 A;  4C0A A;  1MKE A;  2D9X A;  2EMS A;  2YT0 A;  1I2H A;  3PZD A;  3TW1 A;  1GG3 A;  2RLO A;  3AJ4 A;  4DX9 0;  3NSU A;  4L6E A;  1J19 A;  3PVU A;  1U2B A;  4HB4 B;  1TQZ A;  4F7G A;  2K00 A;  5DIF B;  1Z87 A;  5D3V A;  2Y8G A;  4HDO A;  2DLW A;  2KUP A;  1ZVR A;  3P6A A;  2ZPY A;  1DBH A;  5EFX A;  2R09 A;  3MPX A;  1MAI A;  4A5K A;  4HAT B;  2J0J A;  1W1G A;  3AU4 A;  4Z2N A;  1LB1 A;  2P0H A;  4KHB B;  2DHJ A;  4ZRI A;  1FHX A;  2RNR B;  1BAK A;  4A6F A;  2YS1 A;  5DHF B;  2YVC A;  4CHM A;  5KQ1 A;  3KRW A;  2P0D A;  2NMB A;  1IRS A;  2VKI A;  3SNH A;  3GYP A;  1BTN A;  5FI1 A;  2OQB A;  2YRY A;  4A6F B;  2PZ1 A;  2DYN A;  3AU5 A;  4HHV A;  2L2I A;  2QKM A;  1DDV A;  1NI2 A;  1P3R A;  2DYQ A;  3P7Z A;  1UNR A;  2Z0P A;  4NSW A;  2W2X C;  2XQN M;  2IYB A;  4ZRK A;  2DA0 A;  4H8S A;  2MFQ A;  1TXD A;  1NTV A;  3O96 A;  3BJI A;  1UPQ A;  3ODO A;  5JHG A;  4HB3 B;  3ODW A;  2AL6 A;  1XCG A;  1MIZ B;  2VSZ A;  2N23 A;  3DXD A;  3A98 B;  1FHW A;  4HAX B;  2GJY A;  1X05 A;  4K2P A;  2I1J A;  2N0Y A;  1FGZ A;  5JLJ B;  1TJ6 A;  4D0N B;  3BIN A;  4WJ7 A;  3F5R A;  1H4R A;  4HB2 B;  1ZC4 B;  3A8P A;  1QQG A;  4EMO A;  4CYE A;  5KQ4 A;  3D8F A;  2DX1 A;  2LYD A;  5CLQ B;  5D3Y A;  2V76 A;  3TCA A;  4K2O A;  2J59 M;  4HB0 B;  2LG1 A;  4WSF A;  4KHA A;  1M7R A;  2DHI A;  4HAW B;  5HE1 A;  2Q13 A;  2HE7 A;  4DXA B;  2GCL A;  1AWE A;  1OY2 A;  2CY5 A;  4GPT B;  2R0D A;  3PG7 A;  2D9W A;  3IVF A;  2P0F A;  2UZS A;  1K5G B;  2UZR A;  2RUK B;  3PEG A;  1RRP B;  2DX5 A;  2YT1 A;  2Z0O A;  1EF1 A;  3WYF B;  5J3T A;  4DX8 A;  2RSG A;  3F0W A;  4HAV B;  3U7D A;  4NY0 A;  1X86 A;  2IFS A;  3KSY A;  1PLS A;  1KZG A;  1W1D A;  1RJ2 A;  3D8E A;  4WVF B;  1EVH A;  1KZ7 A;  3KRX A;  2RGN B;  1AQC A;  2YSZ A;  4TKN A;  4IFS A;  3ML4 A;  3V5W A;  2YF0 A;  4GN1 A;  1FB8 A;  1B55 A;  1EAZ A;  3QBV B;  5KCV A;  2LOZ A;  1GC7 A;  5JHH A;  4F7U P;  1Y19 B;  1W1H A;  3WA0 A;  1ZC3 B;  2CY4 A;  2ROZ B;  1U5G A;  3FSS A;  1KI1 B;  2J0K A;  4A6K A;  3TFM A;  5LOP B;  2D10 A;  3LJU X;  1WI1 A;  1P6S A;  1DRO A;  3ODX A;  3TO1 A;  2CRF A;  3U8Z A;  5FI0 A;  4KHO A;  2D9Y A;  4GZU A;  3ULC A;  1LW3 A;  1XX0 A;  1WVH A;  5DHA B;  3M1I B;  1UEF A;  1FAO A;  5C5B A;  1WG7 A;  2RVB B;  5HE3 A;  1PFJ A;  4XWX A;  1X1G A;  5HE0 A;  3MDB C;  4ZRJ A;  1V89 A;  3N7C A;  1SGH A;  5C5B B;  3VIA A;  5C79 A;  2QKL A;  2D2Q A;  2M38 A;  4GMV A;  1MK7 B;  4IOY X;  1NTY A;  2CAY A;  2LOX A;  2DFK A;  2P8V A;  1N3H A;  4DBB A;  3CXB B;  1ZSQ A;  5D3W A;  1UNQ A;  1U27 A;  2VRW B;  4B6H A;  2COF A;  4GXB A;  2Y8F A;  4GMX B;  5J3Q A;  4P7I A;  2BCJ A;  3ZDT A;  1U5F A;  2FJL A;  5C6R A;  1K5D B;  2K2U A;  1U29 A;  3FEH A;  1FGY A;  1X1F A;  2HTH B;  2J0M A;  1J0W A;  3PVL A;  2Z0Q A;  5GOW B;  1WGQ A;  5DH9 B;  3QWM A;  2DTC A;  2JP2 A;  2MWN B;  4YL8 A;  1DDW A;  2ELB A;  3PP2 A;  3G9W A;  1MPH A;  3KY9 A;  4MK0 A;  3HK0 A;  1BTK A;  3FM8 C;  2W2X D;  2AEH A;  1U5E A;  3RCP A;  3PVW A;  4KAX B;  4KVG B;  4EJN A;  1EGX A;  4MT7 A;  2COA A;  1OMW A;  2M14 A;  3X23 A;  2DKQ A;  1I7A A;  1NU2 A;  2D9V A;  2KCJ A;  4TYZ A;  1P5T A;  1SHC A;  1X11 A;  2DN6 A;  3SYX A;  5D27 A;  2I5C A;  3TVV A;  2UVM A;  3HW2 B;  3OAN A;  2L1C A;  1DDM A;  3ZVR A;  5C16 A;  2EJ8 A;  3SV1 A;  3SO6 A;  2MDX A;  1ZM0 A;  2YS3 A;  1V5M A;  2K2J A;  1GC6 A;  5CLL B;  4BBK A;  2D9Z A;  2Y7B A;  1MK9 B;  1Y5O A;  5JP4 A;  3A8Q A;  1DYN A;  4PNK A;  3PSC A;  3UZT A;  1QC6 A;  1MIX A;  1V5U A;  1OQN A;  3VOQ A;  2OTX A;  2COC A;  4HAZ B;  2MKR A;  4IAP A;  1XKE A;  3QIJ A;  2D4Q A;  4PQ0 A;  3KZ1 A;  4A6H A;  2DHK A;  3GYO A;  5DI9 B;  3HQC A;  1H10 A;  2EMT A;  2GCJ A;  1WGU A;  4K81 A;  3ULB A;  1UPR A;  1XOD A;  2I1K A;  1ISN A;  2KGX B;  1Q67 A; 
#chains in the Genus database with same CATH topology
 2DKP A;  4HAU B;  5HE2 A;  4MY6 A;  2G35 A;  3CIK A;  5LON B;  1V5P A;  2ADZ A;  3D8D A;  4YON A;  5L81 A;  2I5F A;  4K17 A;  3DXE A;  4HAY B;  3HSA A;  1WJ1 A;  3T06 A;  5J3Y A;  5D3X A;  4Z2M B;  2ELA A;  2KUQ A;  2H7D A;  1FOE A;  4EKU A;  1BWN A;  3SUZ A;  2EC1 A;  1UNP A;  1PMS A;  2LKO A;  2RRF A;  2LUL A;  4CHJ A;  1XD4 A;  1E5W A;  2ROV A;  1V61 A;  2D11 A;  2X18 A;  4Y94 A;  1XR0 B;  1WJM A;  1U5D A;  2NZ8 B;  2H7E A;  2COD A;  2GS0 A;  4QXA B;  1M7E A;  4F7H A;  2YS5 A;  2E2X A;  1FHO A;  4HDQ A;  2W2W A;  3DXC A;  1V88 A;  4C0A A;  1MKE A;  2D9X A;  2EMS A;  2YT0 A;  1I2H A;  3PZD A;  3TW1 A;  1GG3 A;  2RLO A;  3AJ4 A;  4DX9 0;  3NSU A;  4L6E A;  1J19 A;  3PVU A;  1U2B A;  4HB4 B;  4QJ3 B;  1TQZ A;  4F7G A;  2K00 A;  5DIF B;  1Z87 A;  5D3V A;  2Y8G A;  4HDO A;  2DLW A;  2KUP A;  1ZVR A;  3P6A A;  2ZPY A;  4KHB A;  1DBH A;  3NW8 A;  5EFX A;  2R09 A;  3MPX A;  1MAI A;  4A5K A;  4HAT B;  2J0J A;  1W1G A;  3AU4 A;  4Z2N A;  1LB1 A;  2P0H A;  4KHB B;  2DHJ A;  4ZRI A;  1FHX A;  2RNR B;  1BAK A;  4A6F A;  2YS1 A;  1MI1 A;  5DHF B;  2YVC A;  4CHM A;  5KQ1 A;  3KRW A;  2P0D A;  2NMB A;  1IRS A;  2VKI A;  3SNH A;  3GYP A;  1BTN A;  5FI1 A;  2OQB A;  2YRY A;  4A6F B;  2PZ1 A;  2DYN A;  3AU5 A;  4HHV A;  2L2I A;  2QKM A;  1DDV A;  1NI2 A;  1P3R A;  2DYQ A;  3P7Z A;  1UNR A;  2Z0P A;  3NWF A;  4NSW A;  2FJU B;  2W2X C;  4CSQ A;  2XQN M;  2IYB A;  4ZRK A;  2DA0 A;  4H8S A;  5I2M A;  2MFQ A;  1TXD A;  2GUM A;  1NTV A;  3O96 A;  2Z13 A;  3BJI A;  1UPQ A;  3ODO A;  5JHG A;  4HB3 B;  3ODW A;  2AL6 A;  4QJ5 B;  1XCG A;  1MIZ B;  2VSZ A;  2N23 A;  3DXD A;  2Z14 A;  2Z4D A;  3A98 B;  1FHW A;  4HAX B;  2GJY A;  1X05 A;  4K2P A;  3HIE A;  2I1J A;  2N0Y A;  1FGZ A;  5JLJ B;  1TJ6 A;  4D0N B;  3BIN A;  4WJ7 A;  3F5R A;  1H4R A;  4HB2 B;  4D6W A;  1ZC4 B;  3OHM B;  3A8P A;  1QQG A;  4EMO A;  4CYE A;  5KQ4 A;  3D8F A;  2DX1 A;  2LYD A;  5CLQ B;  5D3Y A;  2V76 A;  3NWA A;  3TCA A;  4K2O A;  2J59 M;  4HB0 B;  2LG1 A;  4WSF A;  4KHA A;  1M7R A;  2DHI A;  4HAW B;  5M4Y B;  2KR0 A;  5HE1 A;  2Q13 A;  2HE7 A;  4DXA B;  2GCL A;  3NWD A;  1AWE A;  1OY2 A;  2K8E A;  2CY5 A;  4GPT B;  2R0D A;  3PG7 A;  4GOU A;  2D9W A;  3IVF A;  5LG4 B;  2P0F A;  2UZS A;  1K5G B;  2UZR A;  2RUK B;  3PEG A;  1RRP B;  2DX5 A;  2YT1 A;  2Z0O A;  1EF1 A;  3WYF B;  5J3T A;  4DX8 A;  2RSG A;  3F0W A;  4HAV B;  3U7D A;  4NY0 A;  1X86 A;  2IFS A;  3KSY A;  1PLS A;  1KZG A;  1W1D A;  1RJ2 A;  3D8E A;  4WVF B;  1EVH A;  1KZ7 A;  3KRX A;  2KIE A;  2RGN B;  1AQC A;  2YSZ A;  4OT1 A;  4TKN A;  4IFS A;  3ML4 A;  3V5W A;  3DCX A;  2YF0 A;  4GN1 A;  1FB8 A;  1B55 A;  1EAZ A;  3QBV B;  5KCV A;  2LOZ A;  1GC7 A;  5JHH A;  4F7U P;  1Y19 B;  4L1R A;  2Z59 A;  1W1H A;  3WA0 A;  1ZC3 B;  2CY4 A;  2ROZ B;  1U5G A;  3FSS A;  1KI1 B;  4HSI A;  2J0K A;  4A6K A;  3TFM A;  5LOP B;  2D10 A;  3LJU X;  1WI1 A;  1P6S A;  1DRO A;  3ODX A;  3TO1 A;  2CRF A;  3U8Z A;  4QJ4 B;  5FI0 A;  4KHO A;  2D9Y A;  4GZU A;  3ULC A;  1LW3 A;  1XX0 A;  1WVH A;  5DHA B;  2NBV A;  3M1I B;  1UEF A;  1FAO A;  5C5B A;  1WG7 A;  2RVB B;  5HE3 A;  1PFJ A;  4XWX A;  1X1G A;  5HE0 A;  3MDB C;  4ZRJ A;  1V89 A;  3N7C A;  1SGH A;  5C5B B;  3VIA A;  5C79 A;  5I2S A;  2QKL A;  2D2Q A;  2M38 A;  4GMV A;  1MK7 B;  4IOY X;  1NTY A;  2CAY A;  2LOX A;  2DFK A;  2P8V A;  1N3H A;  1ZYI A;  4DBB A;  3CXB B;  1ZSQ A;  5D3W A;  1UNQ A;  1U27 A;  2VRW B;  4B6H A;  2COF A;  4GXB A;  2Y8F A;  4GMX B;  5J3Q A;  4P7I A;  2BCJ A;  3B77 A;  3ZDT A;  1U5F A;  2FJL A;  5C6R A;  1K5D B;  2K2U A;  1U29 A;  3FEH A;  1FGY A;  1X1F A;  2HTH B;  2J0M A;  1J0W A;  3PVL A;  2Z0Q A;  5GOW B;  1WGQ A;  5DH9 B;  3QWM A;  2DTC A;  2JP2 A;  2MWN B;  4YL8 A;  1DDW A;  2ELB A;  3PP2 A;  3G9W A;  1MPH A;  3KY9 A;  4MK0 A;  2KIG A;  4OSN A;  3HK0 A;  1BTK A;  3FM8 C;  2W2X D;  2AEH A;  1U5E A;  3RCP A;  3PVW A;  4KAX B;  4KVG B;  4EJN A;  1EGX A;  4MT7 A;  2COA A;  1OMW A;  2M14 A;  3X23 A;  2DKQ A;  1I7A A;  3A58 A;  1NU2 A;  2D9V A;  2KCJ A;  4TYZ A;  1P5T A;  1SHC A;  1X11 A;  4DIX A;  2DN6 A;  3SYX A;  5D27 A;  3U12 A;  2YT2 A;  2I5C A;  3TVV A;  2UVM A;  3HW2 B;  3OAN A;  2R2Y A;  2L1C A;  1DDM A;  3ZVR A;  5C16 A;  2EJ8 A;  3SV1 A;  3SO6 A;  2MDX A;  1ZM0 A;  1T77 A;  2YS3 A;  1V5M A;  2K2J A;  1GC6 A;  5CLL B;  4BBK A;  2D9Z A;  2Y7B A;  1MK9 B;  1Y5O A;  5JP4 A;  3A8Q A;  1DYN A;  4PNK A;  3PSC A;  3UZT A;  1QC6 A;  1MIX A;  1V5U A;  1OQN A;  3VOQ A;  2OTX A;  3FVC A;  2ZKM X;  2COC A;  4HAZ B;  4GNK B;  2MKR A;  4IAP A;  1XKE A;  3QIJ A;  2D4Q A;  4PQ0 A;  3KZ1 A;  4A6H A;  2DHK A;  3GYO A;  5DI9 B;  3HQC A;  1H10 A;  2EMT A;  2GCJ A;  1WGU A;  4K81 A;  3ULB A;  2K49 A;  5IRS A;  1UPR A;  1XOD A;  2I1K A;  1ISN A;  2KGX B;  1Q67 A; 
#chains in the Genus database with same CATH homology
 2DKP A;  4HAU B;  5HE2 A;  4MY6 A;  2G35 A;  3CIK A;  5LON B;  1V5P A;  2ADZ A;  3D8D A;  4YON A;  5L81 A;  2I5F A;  4K17 A;  3DXE A;  4HAY B;  1WJ1 A;  3T06 A;  5J3Y A;  5D3X A;  4Z2M B;  2ELA A;  2H7D A;  1FOE A;  4EKU A;  1BWN A;  3SUZ A;  2EC1 A;  1UNP A;  1PMS A;  2LKO A;  2LUL A;  4CHJ A;  1XD4 A;  1E5W A;  2ROV A;  1V61 A;  2D11 A;  2X18 A;  4Y94 A;  1XR0 B;  1WJM A;  1U5D A;  2NZ8 B;  2H7E A;  2COD A;  2GS0 A;  1M7E A;  4F7H A;  2YS5 A;  2E2X A;  1FHO A;  4HDQ A;  2W2W A;  3DXC A;  1V88 A;  4C0A A;  1MKE A;  2D9X A;  2EMS A;  2YT0 A;  1I2H A;  3PZD A;  3TW1 A;  1GG3 A;  2RLO A;  3AJ4 A;  4DX9 0;  3NSU A;  4L6E A;  1J19 A;  3PVU A;  1U2B A;  4HB4 B;  1TQZ A;  4F7G A;  2K00 A;  5DIF B;  1Z87 A;  5D3V A;  2Y8G A;  4HDO A;  2DLW A;  2KUP A;  1ZVR A;  3P6A A;  2ZPY A;  1DBH A;  5EFX A;  2R09 A;  3MPX A;  1MAI A;  4A5K A;  4HAT B;  2J0J A;  1W1G A;  3AU4 A;  4Z2N A;  1LB1 A;  2P0H A;  4KHB B;  2DHJ A;  4ZRI A;  1FHX A;  2RNR B;  1BAK A;  4A6F A;  2YS1 A;  5DHF B;  2YVC A;  4CHM A;  5KQ1 A;  3KRW A;  2P0D A;  2NMB A;  1IRS A;  2VKI A;  3SNH A;  3GYP A;  1BTN A;  5FI1 A;  2OQB A;  2YRY A;  4A6F B;  2PZ1 A;  2DYN A;  3AU5 A;  4HHV A;  2L2I A;  2QKM A;  1DDV A;  1NI2 A;  1P3R A;  2DYQ A;  3P7Z A;  1UNR A;  2Z0P A;  4NSW A;  2W2X C;  2XQN M;  2IYB A;  4ZRK A;  2DA0 A;  4H8S A;  2MFQ A;  1TXD A;  1NTV A;  3O96 A;  3BJI A;  1UPQ A;  3ODO A;  5JHG A;  4HB3 B;  3ODW A;  2AL6 A;  1XCG A;  1MIZ B;  2VSZ A;  2N23 A;  3DXD A;  3A98 B;  1FHW A;  4HAX B;  2GJY A;  1X05 A;  4K2P A;  2I1J A;  2N0Y A;  1FGZ A;  5JLJ B;  1TJ6 A;  4D0N B;  3BIN A;  4WJ7 A;  3F5R A;  1H4R A;  4HB2 B;  1ZC4 B;  3A8P A;  1QQG A;  4EMO A;  4CYE A;  5KQ4 A;  3D8F A;  2DX1 A;  2LYD A;  5CLQ B;  5D3Y A;  2V76 A;  3TCA A;  4K2O A;  2J59 M;  4HB0 B;  2LG1 A;  4WSF A;  4KHA A;  1M7R A;  2DHI A;  4HAW B;  5HE1 A;  2Q13 A;  2HE7 A;  4DXA B;  2GCL A;  1AWE A;  1OY2 A;  2CY5 A;  4GPT B;  2R0D A;  3PG7 A;  2D9W A;  3IVF A;  2P0F A;  2UZS A;  1K5G B;  2UZR A;  2RUK B;  3PEG A;  1RRP B;  2DX5 A;  2YT1 A;  2Z0O A;  1EF1 A;  3WYF B;  5J3T A;  4DX8 A;  2RSG A;  3F0W A;  4HAV B;  3U7D A;  4NY0 A;  1X86 A;  2IFS A;  3KSY A;  1PLS A;  1KZG A;  1W1D A;  1RJ2 A;  3D8E A;  4WVF B;  1EVH A;  1KZ7 A;  3KRX A;  2RGN B;  1AQC A;  2YSZ A;  4TKN A;  4IFS A;  3ML4 A;  3V5W A;  2YF0 A;  4GN1 A;  1FB8 A;  1B55 A;  1EAZ A;  3QBV B;  5KCV A;  2LOZ A;  1GC7 A;  5JHH A;  4F7U P;  1Y19 B;  1W1H A;  3WA0 A;  1ZC3 B;  2CY4 A;  2ROZ B;  1U5G A;  3FSS A;  1KI1 B;  2J0K A;  4A6K A;  3TFM A;  5LOP B;  2D10 A;  3LJU X;  1WI1 A;  1P6S A;  1DRO A;  3ODX A;  3TO1 A;  2CRF A;  3U8Z A;  5FI0 A;  4KHO A;  2D9Y A;  4GZU A;  3ULC A;  1LW3 A;  1XX0 A;  1WVH A;  5DHA B;  3M1I B;  1UEF A;  1FAO A;  5C5B A;  1WG7 A;  2RVB B;  5HE3 A;  1PFJ A;  4XWX A;  1X1G A;  5HE0 A;  3MDB C;  4ZRJ A;  1V89 A;  3N7C A;  1SGH A;  5C5B B;  3VIA A;  5C79 A;  2QKL A;  2D2Q A;  2M38 A;  4GMV A;  1MK7 B;  4IOY X;  1NTY A;  2CAY A;  2LOX A;  2DFK A;  2P8V A;  1N3H A;  4DBB A;  3CXB B;  1ZSQ A;  5D3W A;  1UNQ A;  1U27 A;  2VRW B;  4B6H A;  2COF A;  4GXB A;  2Y8F A;  4GMX B;  5J3Q A;  4P7I A;  2BCJ A;  3ZDT A;  1U5F A;  2FJL A;  5C6R A;  1K5D B;  2K2U A;  1U29 A;  3FEH A;  1FGY A;  1X1F A;  2HTH B;  2J0M A;  1J0W A;  3PVL A;  2Z0Q A;  5GOW B;  1WGQ A;  5DH9 B;  3QWM A;  2DTC A;  2JP2 A;  2MWN B;  4YL8 A;  1DDW A;  2ELB A;  3PP2 A;  3G9W A;  1MPH A;  3KY9 A;  4MK0 A;  3HK0 A;  1BTK A;  3FM8 C;  2W2X D;  2AEH A;  1U5E A;  3RCP A;  3PVW A;  4KAX B;  4KVG B;  4EJN A;  1EGX A;  4MT7 A;  2COA A;  1OMW A;  2M14 A;  3X23 A;  2DKQ A;  1I7A A;  1NU2 A;  2D9V A;  2KCJ A;  4TYZ A;  1P5T A;  1SHC A;  1X11 A;  2DN6 A;  3SYX A;  5D27 A;  2I5C A;  3TVV A;  2UVM A;  3HW2 B;  3OAN A;  2L1C A;  1DDM A;  3ZVR A;  5C16 A;  2EJ8 A;  3SV1 A;  3SO6 A;  2MDX A;  1ZM0 A;  2YS3 A;  1V5M A;  2K2J A;  1GC6 A;  5CLL B;  4BBK A;  2D9Z A;  2Y7B A;  1MK9 B;  1Y5O A;  5JP4 A;  3A8Q A;  1DYN A;  4PNK A;  3PSC A;  3UZT A;  1QC6 A;  1MIX A;  1V5U A;  1OQN A;  3VOQ A;  2OTX A;  2COC A;  4HAZ B;  2MKR A;  4IAP A;  1XKE A;  3QIJ A;  2D4Q A;  4PQ0 A;  3KZ1 A;  4A6H A;  2DHK A;  3GYO A;  5DI9 B;  3HQC A;  1H10 A;  2EMT A;  2GCJ A;  1WGU A;  4K81 A;  3ULB A;  1UPR A;  1XOD A;  2I1K A;  1ISN A;  2KGX B;  1Q67 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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