2YDFA

Human serum albumin complexed with iophenoxic acid
Total Genus 212
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
212
sequence length
578
structure length
569
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVAADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystallographic Analysis Reveals the Structural Basis of the High-Affinity Binding of Iophenoxic Acid to Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 212
structure length 569
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2ydfA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2ydfA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2ydfA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2ydfA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2ydfA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2ydfA05
3SQJA 4OT2A 1E7EA 2BXKA 5DBYA 1UORA 2BXLA 2XVQA 2XVWA 2BXAA 1BM0A 3UIVA 5IJEA 2BXNA 1AO6A 2BXFA 4BKEA 1HK3A 4L9QA 1GNJA 1HK1A 1O9XA 4LB9A 5ID9A 2BXGA 1BJ5A 1E7AA 2BXCA 4K2CA 2BXHA 2XSIA 2BXIA 4PO0A 1TF0A 2BXBA 2XW1A 1HK2A 5GHKA 2I30A 5IIHA 2VUFA 2VDBA 4LB2A 3CX9A 1HA2A 2BXMA 2BX8A 4EMXA 2I2ZA 5IJ5A 4JK4A 4LUFA 2BXOA 3V03A 1E7BA 4ZBRA 1MA9A 5DQFA 1J7EA 4S1YA 3LU6A 3TDLA 1GNIA 1LOTA 1N5UA 4N0UD 4K71A 1H9ZA 4LA0A 4E99A 1KXPD 2BXEA 4F5SA 4HGMB 3LU8A 5ID7A 1E7HA 5HOZA 1HK5A 3V09A 3JQZA 3A73A 4IW2A 1E7FA 1E7CA 3LU7A 4OR0A 3B9LA 2VUEA 4L9KA 4J2VA 4G03A 2BXDA 1BKEA 2YDFA 4HGKA 1E7GA 5IJFA 3B9MA 1E78A 4F5TA 2XW0A 4L8UA 4ZBQA 5IIUA 2BXPA 5FUOA 4F5UA 5IFOA 2BXQA 1HK4A 1J78A 1E7IA 5IIXA 4G04A 4IW1A 2XVUA 3JRYA 2XVVA 1KW2A 4F5VA 3V08A 4Z69A 4N0FD 4LUHA
chains in the Genus database with same CATH superfamily
4FK5B 2KWFA 2LXSA 3SQJA 3ECPA 4OT2A 1E7EA 2BXKA 3MHSB 2EFEA 5DBYA 2AGHB 1UORA 3WHQA 2BXLA 2XVQA 1TXUA 4WA6B 3H37A 2XVWA 3SIUB 2BXAA 1BM0A 1H5WA 3UIVA 5GIOA 5IJEA 3FNMA 2BXNA 2GUTA 1AO6A 2BXFA 4BKEA 1HK3A 4L9QA 1MM8A 5GIPA 1GNJA 3WHSA 4G01A 1HK1A 1O9XA 3FWCC 4LB9A 5ID9A 2BXGA 1KDXA 1BJ5A 4D7XA 1E7AA 3NVIA 2KBZA 3KIKA 2BXCA 1MIYA 4K2CA 3NVKA 2BXHA 4GDKB 1MIWA 2XSIA 2BXIA 4PO0A 1TF0A 2BXBA 2XW1A 1HK2A 2LQIA 3MHHB 5GHKA 2I30A 3BPJA 2VUFA 5IIHA 3NMUA 2VDBA 2XMOA 3GQXA 4LB2A 3CX9A 4GDLB 1HA2A 2BXMA 5D7GA 3W1SA 5B5TA 2DBXA 4FIPB 2BX8A 4EMXA 2DBWA 2I2ZA 5IJ5A 4JK4A 3GA9L 4I9OA 4ZUXV 2Z8JA 4LUFA 2LXTA 2AJEA 4ZCGA 2BXOA 1IJGA 3V03A 1E7BA 4ZBRA 2DBUA 1FOUA 1VFIA 3A75A 3H3AA 2E0XA 1MUHA 1MA9A 2EFCA 2Z8KA 4ZBKA 5BPKA 1JNBA 2CKXA 2DG5A 5DQFA 1J7EA 4S1YA 4FJCB 3LU6A 1VZSA 3TDLA 1GNIA 1LOTA 3PLAA 2LQHA 3GQUA 1N5UA 3KJLA 4W4UB 4N0UD 3WHRA 4K71A 1H9ZA 4LA0A 4N3ZA 4E99A 3SIVB 3G9KD 1NT2B 1KXPD 2BXEA 4F5SA 2NNWA 4HGMB 3LU8A 5ID7A 1E7HA 5HOZA 4TQ0A 2EFHA 5GINA 1HK5A 3V09A 2QMCA 3JQZA 3A73A 4IW2A 1SB0A 1E7FA 3M99C 1E7CA 2OZBB 3LU7A 4OR0A 4Z9OA 2JUHA 4OTUA 2DYOA 4C31B 3B9LA 2VUEA 2DYMA 2EFDA 4GDXA 2OT3A 4L9KA 4J2VA 4G03A 2BXDA 2QM6A 1BKEA 2ROHA 2YDFA 4HGKA 4GG2A 1E7GA 5IJFA 2V36A 3B9MA 4ZC6A 1E78A 4F5TA 2Z8IA 4TQ1A 2K0NA 3ICXA 2QHBA 2LOQA 2NQOA 2XW0A 4L8UA 2BXPA 4ZBQA 4F5UA 5FUOA 5IIUA 5IFOA 2BXQA 1HK4A 3VQIA 1J78A 4M70B 1E7IA 5IIXA 4DHXB 4MBEC 4DM0A 1MUSA 4G04A 4IW1A 4OTTA 2XVUA 4NAWB 3JRYA 2XVVA 1KW2A 4F5VA 3V08A 4Z69A 4BY9C 3NVMA 4N0FD 1MIVA 2E0YA 1LNSA 3FWBC 4LUHA
chains in the Genus database with same CATH topology
4FK5B 3SQJA 4OT2A 1E7EA 2BXKA 3MHSB 2EFEA 5DBYA 1UORA 3WHQA 2BXLA 2XVQA 1TXUA 4WA6B 3H37A 2XVWA 3SIUB 2BXAA 1BM0A 1H5WA 3UIVA 5GIOA 5IJEA 3FNMA 2BXNA 1AO6A 2BXFA 4BKEA 1HK3A 4L9QA 5GIPA 1GNJA 3WHSA 4G01A 1HK1A 1O9XA 3FWCC 4LB9A 5ID9A 2BXGA 1BJ5A 1E7AA 3NVIA 2KBZA 3KIKA 2BXCA 1MIYA 4K2CA 3NVKA 2BXHA 4GDKB 1MIWA 2XSIA 2BXIA 4PO0A 1TF0A 2BXBA 2XW1A 1HK2A 3MHHB 5GHKA 2I30A 5IIHA 2VUFA 3NMUA 2VDBA 2XMOA 3GQXA 4LB2A 3CX9A 4GDLB 1HA2A 2BXMA 5D7GA 3W1SA 5B5TA 2DBXA 4FIPB 2BX8A 4EMXA 2DBWA 2I2ZA 5IJ5A 4JK4A 3GA9L 4ZUXV 2Z8JA 4LUFA 2AJEA 4ZCGA 2BXOA 1IJGA 3V03A 1E7BA 4ZBRA 2DBUA 1FOUA 1VFIA 3A75A 3H3AA 2E0XA 1MA9A 2EFCA 2Z8KA 4ZBKA 5BPKA 1JNBA 2CKXA 2DG5A 5DQFA 1J7EA 4S1YA 4FJCB 3LU6A 1VZSA 3TDLA 1GNIA 1LOTA 3PLAA 3GQUA 3KJLA 1N5UA 4W4UB 3WHRA 4N0UD 3SIVB 4K71A 1H9ZA 4LA0A 4N3ZA 4E99A 3G9KD 1NT2B 1KXPD 2BXEA 4F5SA 2NNWA 4HGMB 3LU8A 5ID7A 1E7HA 5HOZA 4TQ0A 2EFHA 5GINA 1HK5A 3V09A 2QMCA 3JQZA 3A73A 4IW2A 3M99C 1E7FA 1E7CA 2OZBB 3LU7A 4OR0A 4Z9OA 2JUHA 4OTUA 2DYOA 4C31B 3B9LA 2VUEA 2DYMA 2EFDA 4GDXA 2OT3A 4L9KA 4J2VA 4G03A 2BXDA 2QM6A 1BKEA 2ROHA 2YDFA 4HGKA 4GG2A 1E7GA 5IJFA 2V36A 3B9MA 4ZC6A 1E78A 4F5TA 2Z8IA 4TQ1A 3ICXA 2QHBA 2LOQA 2NQOA 2XW0A 4L8UA 2BXPA 4ZBQA 4F5UA 5FUOA 5IIUA 5IFOA 2BXQA 1HK4A 3VQIA 1J78A 4M70B 1E7IA 5IIXA 4DHXB 4MBEC 4G04A 4IW1A 4OTTA 2XVUA 4NAWB 3JRYA 2XVVA 1KW2A 4F5VA 3V08A 4Z69A 4BY9C 3NVMA 4N0FD 1MIVA 2E0YA 1LNSA 3FWBC 4LUHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SQJ A;  4OT2 A;  1E7E A;  2BXK A;  5DBY A;  1UOR A;  2BXL A;  2XVQ A;  2XVW A;  2BXA A;  1BM0 A;  3UIV A;  5IJE A;  2BXN A;  1AO6 A;  2BXF A;  4BKE A;  1HK3 A;  4L9Q A;  1GNJ A;  1HK1 A;  1O9X A;  4LB9 A;  5ID9 A;  2BXG A;  1BJ5 A;  1E7A A;  2BXC A;  4K2C A;  2BXH A;  2XSI A;  2BXI A;  4PO0 A;  1TF0 A;  2BXB A;  2XW1 A;  1HK2 A;  5GHK A;  2I30 A;  5IIH A;  2VUF A;  2VDB A;  4LB2 A;  3CX9 A;  1HA2 A;  2BXM A;  2BX8 A;  4EMX A;  2I2Z A;  5IJ5 A;  4JK4 A;  4LUF A;  2BXO A;  3V03 A;  1E7B A;  4ZBR A;  1MA9 A;  5DQF A;  1J7E A;  4S1Y A;  3LU6 A;  3TDL A;  1GNI A;  1LOT A;  1N5U A;  4N0U D;  4K71 A;  1H9Z A;  4LA0 A;  4E99 A;  1KXP D;  2BXE A;  4F5S A;  4HGM B;  3LU8 A;  5ID7 A;  1E7H A;  5HOZ A;  1HK5 A;  3V09 A;  3JQZ A;  3A73 A;  4IW2 A;  1E7F A;  1E7C A;  3LU7 A;  4OR0 A;  3B9L A;  2VUE A;  4L9K A;  4J2V A;  4G03 A;  2BXD A;  1BKE A;  2YDF A;  4HGK A;  1E7G A;  5IJF A;  3B9M A;  1E78 A;  4F5T A;  2XW0 A;  4L8U A;  4ZBQ A;  5IIU A;  2BXP A;  5FUO A;  4F5U A;  5IFO A;  2BXQ A;  1HK4 A;  1J78 A;  1E7I A;  5IIX A;  4G04 A;  4IW1 A;  2XVU A;  3JRY A;  2XVV A;  1KW2 A;  4F5V A;  3V08 A;  4Z69 A;  4N0F D;  4LUH A; 
#chains in the Genus database with same CATH topology
 4FK5 B;  2KWF A;  2LXS A;  3SQJ A;  3ECP A;  4OT2 A;  1E7E A;  2BXK A;  3MHS B;  2EFE A;  5DBY A;  2AGH B;  1UOR A;  3WHQ A;  2BXL A;  2XVQ A;  1TXU A;  4WA6 B;  3H37 A;  2XVW A;  3SIU B;  2BXA A;  1BM0 A;  1H5W A;  3UIV A;  5GIO A;  5IJE A;  3FNM A;  2BXN A;  2GUT A;  1AO6 A;  2BXF A;  4BKE A;  1HK3 A;  4L9Q A;  1MM8 A;  5GIP A;  1GNJ A;  3WHS A;  4G01 A;  1HK1 A;  1O9X A;  3FWC C;  4LB9 A;  5ID9 A;  2BXG A;  1KDX A;  1BJ5 A;  4D7X A;  1E7A A;  3NVI A;  2KBZ A;  3KIK A;  2BXC A;  1MIY A;  4K2C A;  3NVK A;  2BXH A;  4GDK B;  1MIW A;  2XSI A;  2BXI A;  4PO0 A;  1TF0 A;  2BXB A;  2XW1 A;  1HK2 A;  2LQI A;  3MHH B;  5GHK A;  2I30 A;  3BPJ A;  2VUF A;  5IIH A;  3NMU A;  2VDB A;  2XMO A;  3GQX A;  4LB2 A;  3CX9 A;  4GDL B;  1HA2 A;  2BXM A;  5D7G A;  3W1S A;  5B5T A;  2DBX A;  4FIP B;  2BX8 A;  4EMX A;  2DBW A;  2I2Z A;  5IJ5 A;  4JK4 A;  3GA9 L;  4I9O A;  4ZUX V;  2Z8J A;  4LUF A;  2LXT A;  2AJE A;  4ZCG A;  2BXO A;  1IJG A;  3V03 A;  1E7B A;  4ZBR A;  2DBU A;  1FOU A;  1VFI A;  3A75 A;  3H3A A;  2E0X A;  1MUH A;  1MA9 A;  2EFC A;  2Z8K A;  4ZBK A;  5BPK A;  1JNB A;  2CKX A;  2DG5 A;  5DQF A;  1J7E A;  4S1Y A;  4FJC B;  3LU6 A;  1VZS A;  3TDL A;  1GNI A;  1LOT A;  3PLA A;  2LQH A;  3GQU A;  1N5U A;  3KJL A;  4W4U B;  4N0U D;  3WHR A;  4K71 A;  1H9Z A;  4LA0 A;  4N3Z A;  4E99 A;  3SIV B;  3G9K D;  1NT2 B;  1KXP D;  2BXE A;  4F5S A;  2NNW A;  4HGM B;  3LU8 A;  5ID7 A;  1E7H A;  5HOZ A;  4TQ0 A;  2EFH A;  5GIN A;  1HK5 A;  3V09 A;  2QMC A;  3JQZ A;  3A73 A;  4IW2 A;  1SB0 A;  1E7F A;  3M99 C;  1E7C A;  2OZB B;  3LU7 A;  4OR0 A;  4Z9O A;  2JUH A;  4OTU A;  2DYO A;  4C31 B;  3B9L A;  2VUE A;  2DYM A;  2EFD A;  4GDX A;  2OT3 A;  4L9K A;  4J2V A;  4G03 A;  2BXD A;  2QM6 A;  1BKE A;  2ROH A;  2YDF A;  4HGK A;  4GG2 A;  1E7G A;  5IJF A;  2V36 A;  3B9M A;  4ZC6 A;  1E78 A;  4F5T A;  2Z8I A;  4TQ1 A;  2K0N A;  3ICX A;  2QHB A;  2LOQ A;  2NQO A;  2XW0 A;  4L8U A;  2BXP A;  4ZBQ A;  4F5U A;  5FUO A;  5IIU A;  5IFO A;  2BXQ A;  1HK4 A;  3VQI A;  1J78 A;  4M70 B;  1E7I A;  5IIX A;  4DHX B;  4MBE C;  4DM0 A;  1MUS A;  4G04 A;  4IW1 A;  4OTT A;  2XVU A;  4NAW B;  3JRY A;  2XVV A;  1KW2 A;  4F5V A;  3V08 A;  4Z69 A;  4BY9 C;  3NVM A;  4N0F D;  1MIV A;  2E0Y A;  1LNS A;  3FWB C;  4LUH A; 
#chains in the Genus database with same CATH homology
 4FK5 B;  3SQJ A;  4OT2 A;  1E7E A;  2BXK A;  3MHS B;  2EFE A;  5DBY A;  1UOR A;  3WHQ A;  2BXL A;  2XVQ A;  1TXU A;  4WA6 B;  3H37 A;  2XVW A;  3SIU B;  2BXA A;  1BM0 A;  1H5W A;  3UIV A;  5GIO A;  5IJE A;  3FNM A;  2BXN A;  1AO6 A;  2BXF A;  4BKE A;  1HK3 A;  4L9Q A;  5GIP A;  1GNJ A;  3WHS A;  4G01 A;  1HK1 A;  1O9X A;  3FWC C;  4LB9 A;  5ID9 A;  2BXG A;  1BJ5 A;  1E7A A;  3NVI A;  2KBZ A;  3KIK A;  2BXC A;  1MIY A;  4K2C A;  3NVK A;  2BXH A;  4GDK B;  1MIW A;  2XSI A;  2BXI A;  4PO0 A;  1TF0 A;  2BXB A;  2XW1 A;  1HK2 A;  3MHH B;  5GHK A;  2I30 A;  5IIH A;  2VUF A;  3NMU A;  2VDB A;  2XMO A;  3GQX A;  4LB2 A;  3CX9 A;  4GDL B;  1HA2 A;  2BXM A;  5D7G A;  3W1S A;  5B5T A;  2DBX A;  4FIP B;  2BX8 A;  4EMX A;  2DBW A;  2I2Z A;  5IJ5 A;  4JK4 A;  3GA9 L;  4ZUX V;  2Z8J A;  4LUF A;  2AJE A;  4ZCG A;  2BXO A;  1IJG A;  3V03 A;  1E7B A;  4ZBR A;  2DBU A;  1FOU A;  1VFI A;  3A75 A;  3H3A A;  2E0X A;  1MA9 A;  2EFC A;  2Z8K A;  4ZBK A;  5BPK A;  1JNB A;  2CKX A;  2DG5 A;  5DQF A;  1J7E A;  4S1Y A;  4FJC B;  3LU6 A;  1VZS A;  3TDL A;  1GNI A;  1LOT A;  3PLA A;  3GQU A;  3KJL A;  1N5U A;  4W4U B;  3WHR A;  4N0U D;  3SIV B;  4K71 A;  1H9Z A;  4LA0 A;  4N3Z A;  4E99 A;  3G9K D;  1NT2 B;  1KXP D;  2BXE A;  4F5S A;  2NNW A;  4HGM B;  3LU8 A;  5ID7 A;  1E7H A;  5HOZ A;  4TQ0 A;  2EFH A;  5GIN A;  1HK5 A;  3V09 A;  2QMC A;  3JQZ A;  3A73 A;  4IW2 A;  3M99 C;  1E7F A;  1E7C A;  2OZB B;  3LU7 A;  4OR0 A;  4Z9O A;  2JUH A;  4OTU A;  2DYO A;  4C31 B;  3B9L A;  2VUE A;  2DYM A;  2EFD A;  4GDX A;  2OT3 A;  4L9K A;  4J2V A;  4G03 A;  2BXD A;  2QM6 A;  1BKE A;  2ROH A;  2YDF A;  4HGK A;  4GG2 A;  1E7G A;  5IJF A;  2V36 A;  3B9M A;  4ZC6 A;  1E78 A;  4F5T A;  2Z8I A;  4TQ1 A;  3ICX A;  2QHB A;  2LOQ A;  2NQO A;  2XW0 A;  4L8U A;  2BXP A;  4ZBQ A;  4F5U A;  5FUO A;  5IIU A;  5IFO A;  2BXQ A;  1HK4 A;  3VQI A;  1J78 A;  4M70 B;  1E7I A;  5IIX A;  4DHX B;  4MBE C;  4G04 A;  4IW1 A;  4OTT A;  2XVU A;  4NAW B;  3JRY A;  2XVV A;  1KW2 A;  4F5V A;  3V08 A;  4Z69 A;  4BY9 C;  3NVM A;  4N0F D;  1MIV A;  2E0Y A;  1LNS A;  3FWB C;  4LUH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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