2Z0PA

Crystal structure of ph domain of bruton's tyrosine kinase
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
167
structure length
158
Chain Sequence
AAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQIL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the Bruton's tyrosine kinase PH domain with phosphatidylinositol
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Tyrosine-protein kinase BTK
total genus 34
structure length 158
sequence length 167
chains with identical sequence B, C, D
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2007-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF00779 BTK BTK motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2z0pA00
2RLOA 4K2PA 3FSSA 1W1GA 1FGZA 4WVFB 2LKOA 2MFQA 3A8QA 4HDOA 3DXDA 4F7HA 5DHAB 1ZC3B 1FHOA 2COFA 2L2IA 1Z87A 1P6SA 2LOXA 3GYPA 2DHKA 1QC6A 1RRPB 2DLWA 3AU5A 4PQ0A 4C0AA 2I1JA 2P0HA 4A6FA 2IFSA 2X18A 2K00A 1DDWA 1H4RA 1UEFA 1V5UA 3SV1A 1J19A 2CAYA 1DBHA 3PVWA 2DKPA 1X1GA 2YT1A 2Z0QA 3OANA 3PP2A 2ELAA 3FM8C 5C79A 2I5CA 2ZPYA 4NY0A 5C16A 2DKQA 1Y19B 5LONB 3QWMA 5D3VA 3NSUA 2DX1A 3PSCA 1V61A 2QKLA 1UNPA 2EMSA 3P7ZA 2P8VA 1K5DB 4EJNA 1NI2A 3KY9A 4HHVA 1P5TA 4CHJA 3BJIA 4YONA 4HAXB 3WYFB 4HAUB 5KCVA 2K2JA 4DX90 1EGXA 1X1FA 5FI0A 5GOWB 1LW3A 4WJ7A 4EMOA 2QKMA 1IRSA 2H7EA 1AQCA 1XR0B 4K2OA 3ZVRA 1NTVA 1EF1A 2D4QA 2LYDA 2MKRA 1UNQA 2M38A 2ROZB 3DXEA 1ZM0A 2RVBB 2LULA 4HATB 4GZUA 3PZDA 3RCPA 2Z0PA 1KZ7A 1DROA 2YSZA 3F0WA 2L1CA 2UZRA 1M7EA 3KRXA 2JP2A 5EFXA 4B6HA 1X86A 2MDXA 1SHCA 2D9VA 3MPXA 3KZ1A 4WSFA 2J59M 1MPHA 2LG1A 2DFKA 2D9XA 2W2WA 4HDQA 2E2XA 2V76A 3TO1A 5C5BB 4K17A 2J0KA 1H10A 2P0DA 2LOZA 2NZ8B 3IVFA 1QQGA 1FGYA 1U29A 3SUZA 3T06A 1XODA 3N7CA 1DYNA 2BCJA 5KQ4A 4H8SA 3SYXA 1ISNA 1XCGA 3QBVB 1UPRA 3TCAA 3KRWA 1U27A 4Z2NA 1FHWA 2KGXB 4HB2B 1Y5OA 1BTKA 3M1IB 2W2XD 1V88A 3SNHA 4HB0B 2DHIA 2HE7A 4IAPA 1UPQA 3WA0A 4NSWA 1RJ2A 2FJLA 4L6EA 4F7UP 4HB3B 3VIAA 5JHGA 1EVHA 5CLQB 4KVGB 2Q13A 4KHAA 3O96A 3HK0A 1MIXA 2CRFA 1GC7A 2YS3A 2D2QA 5J3QA 2RSGA 4K81A 1TQZA 4A5KA 3D8FA 3F5RA 3ULCA 2YT0A 5CLLB 3AU4A 2EMTA 1X05A 1N3HA 2EC1A 2ROVA 1WJMA 2K2UA 1WJ1A 1I7AA 3P6AA 1MIZB 1WVHA 1LB1A 4HAWB 4A6HA 5D3YA 2Y7BA 1U5DA 3U8ZA 2W2XC 2AL6A 2COAA 1KZGA 1V5MA 2P0FA 4Y94A 3LJUX 1PMSA 1FB8A 4PNKA 2Y8FA 1EAZA 3U7DA 1WGUA 4XWXA 4IOYX 4MT7A 2J0MA 5DIFB 3FEHA 2J0JA 1XD4A 5DI9B 1BAKA 3G9WA 2RNRB 1WG7A 3QIJA 2G35A 2CY5A 5KQ1A 2RGNB 1FHXA 1WI1A 1W1DA 1ZSQA 1MKEA 2R0DA 2H7DA 2PZ1A 2OQBA 2N0YA 2UVMA 3A8PA 2D9ZA 4GPTB 2NMBA 4HAZB 2RUKB 2COCA 4TYZA 3BINA 5J3YA 1MK9B 1OY2A 2DA0A 3GYOA 2GCLA 4KHOA 1ZC4B 1U5FA 4GMXB 4BBKA 5D3WA 4MK0A 3ZDTA 3PVLA 1B55A 1XX0A 1ZVRA 2YS1A 5L81A 1UNRA 3TVVA 1V5PA 5D3XA 4HB4B 4GXBA 1U5GA 3ODWA 4GMVA 1TXDA 5FI1A 3ODOA 2VSZA 1J0WA 3V5WA 3MDBC 3PVUA 2I1KA 3TFMA 4CYEA 1MK7B 2YRYA 2D11A 3ODXA 2VKIA 4ZRKA 1KI1B 1W1HA 5D27A 2DHJA 2YF0A 2YS5A 1NU2A 2ELBA 1K5GB 2Y8GA 5DHFB 1DDVA 2M14A 2D10A 1TJ6A 1Q67A 2EJ8A 3ML4A 2DYQA 4YL8A 4Z2MB 1XKEA 4TKNA 2DN6A 1DDMA 5C6RA 4A6FB 3PG7A 1BWNA 2CY4A 3HW2B 4ZRJA 2MWNB 4F7GA 3D8DA 1FAOA 1MAIA 2ADZA 1AWEA 3D8EA 2DX5A 4DX8A 3VOQA 5DH9B 2HTHB 5LOPB 2GCJA 5J3TA 2Z0OA 2UZSA 1I2HA 2KCJA 1X11A 4DXAB 2YVCA 3CXBB 3TW1A 5JHHA 2N23A 2DTCA 4CHMA 2GS0A 1OMWA 1P3RA 2GJYA 4ZRIA 2XQNM 3AJ4A 3HQCA 1GG3A 2R09A 4GN1A 2AEHA 1PLSA 1BTNA 5HE3A 4EKUA 5C5BA 2VRWB 3PEGA 5HE0A 4P7IA 3DXCA 3SO6A 1OQNA 5JP4A 2OTXA 2I5FA 3A98B 2IYBA 3UZTA 1M7RA 1U2BA 2KUPA 1V89A 2D9YA 1FOEA 4HAVB 3X23A 4KHBB 1GC6A 3KSYA 5JLJB 4DBBA 1E5WA 2CODA 4MY6A 4KAXB 1NTYA 1SGHA 4IFSA 1U5EA 5HE1A 4HAYB 3CIKA 2D9WA 3ULBA 4D0NB 5HE2A 1PFJA 4A6KA 2DYNA 1WGQA
chains in the Genus database with same CATH superfamily
2RLOA 5I2MA 4K2PA 3FSSA 4QJ3B 1W1GA 1FGZA 4WVFB 2GUMA 2LKOA 2MFQA 3A8QA 4HDOA 3DXDA 4F7HA 5DHAB 1ZC3B 1FHOA 2COFA 2L2IA 1Z87A 1P6SA 2LOXA 3GYPA 2DHKA 1QC6A 1RRPB 2DLWA 3AU5A 4PQ0A 4C0AA 2I1JA 2P0HA 4A6FA 2IFSA 2X18A 2K00A 1DDWA 1H4RA 1UEFA 1V5UA 3SV1A 1J19A 2CAYA 1DBHA 3PVWA 4GOUA 2DKPA 1X1GA 2YT1A 2Z0QA 3OANA 3PP2A 2ELAA 4GNKB 2K8EA 2Z4DA 3FM8C 4OT1A 5C79A 2I5CA 3NWAA 2ZPYA 4NY0A 5C16A 2DKQA 1ZYIA 1Y19B 5LONB 3QWMA 5D3VA 3NSUA 2DX1A 3PSCA 1V61A 2QKLA 1UNPA 2EMSA 3P7ZA 2P8VA 2Z14A 1K5DB 4EJNA 1NI2A 2Z59A 3KY9A 4HHVA 1P5TA 4CHJA 3BJIA 4YONA 4HAXB 3WYFB 4HAUB 5KCVA 2K2JA 1MI1A 4DX90 1EGXA 1X1FA 5FI0A 5GOWB 1LW3A 4WJ7A 4EMOA 2QKMA 1IRSA 2H7EA 1AQCA 1XR0B 4K2OA 3ZVRA 1NTVA 1EF1A 2D4QA 2LYDA 2MKRA 1UNQA 2M38A 2ROZB 3DXEA 1ZM0A 2RVBB 2LULA 4HATB 4GZUA 3PZDA 3RCPA 2Z0PA 1KZ7A 1DROA 2YSZA 3F0WA 2L1CA 2UZRA 1M7EA 3KRXA 2JP2A 4L1RA 5EFXA 3DCXA 4B6HA 1X86A 2MDXA 1SHCA 2D9VA 3MPXA 3KZ1A 4WSFA 4QXAB 2J59M 1MPHA 2LG1A 2DFKA 2D9XA 2W2WA 4HDQA 2E2XA 2V76A 3TO1A 5C5BB 4K17A 2J0KA 1H10A 2P0DA 2LOZA 2NZ8B 3IVFA 1QQGA 1FGYA 1U29A 3SUZA 3T06A 1XODA 3N7CA 1DYNA 2BCJA 5KQ4A 4H8SA 3SYXA 1ISNA 1XCGA 4DIXA 3QBVB 1UPRA 3TCAA 3KRWA 1U27A 3B77A 4Z2NA 2KR0A 1FHWA 2KGXB 4HB2B 1Y5OA 1BTKA 3M1IB 2W2XD 1V88A 3SNHA 4HB0B 2DHIA 2HE7A 4IAPA 2KUQA 1UPQA 3WA0A 4NSWA 1RJ2A 2FJLA 4L6EA 4F7UP 2R2YA 4HB3B 3VIAA 5JHGA 1EVHA 5CLQB 4KVGB 2Q13A 4KHAA 3O96A 3HK0A 1MIXA 2CRFA 1GC7A 2YS3A 2D2QA 5J3QA 2KIEA 2RSGA 4K81A 1TQZA 4A5KA 1T77A 3D8FA 3F5RA 3ULCA 2YT0A 5CLLB 3AU4A 2EMTA 1X05A 1N3HA 2EC1A 2ROVA 1WJMA 2K2UA 1WJ1A 1I7AA 3P6AA 1MIZB 1WVHA 1LB1A 4HAWB 4A6HA 5LG4B 4QJ4B 5D3YA 2Y7BA 1U5DA 3U8ZA 2W2XC 3OHMB 4HSIA 2AL6A 2COAA 4QJ5B 1KZGA 1V5MA 2P0FA 4Y94A 3U12A 2FJUB 3LJUX 1PMSA 1FB8A 4PNKA 2Y8FA 1EAZA 3U7DA 1WGUA 4XWXA 4IOYX 4MT7A 4KHBA 2J0MA 5DIFB 3FEHA 2NBVA 3FVCA 2J0JA 1XD4A 5DI9B 1BAKA 3G9WA 3NW8A 2RNRB 1WG7A 3QIJA 2G35A 2CY5A 2K49A 5KQ1A 2RGNB 1FHXA 1WI1A 3A58A 1W1DA 1ZSQA 2Z13A 1MKEA 2R0DA 2H7DA 2PZ1A 2OQBA 2RRFA 2N0YA 2UVMA 3A8PA 2D9ZA 4GPTB 2NMBA 4HAZB 2RUKB 2COCA 4TYZA 3BINA 5J3YA 1MK9B 1OY2A 2DA0A 3GYOA 2GCLA 4KHOA 1ZC4B 1U5FA 3HSAA 4GMXB 4BBKA 5D3WA 4MK0A 3ZDTA 3PVLA 1B55A 1XX0A 1ZVRA 5I2SA 2KIGA 2YS1A 5L81A 1UNRA 3TVVA 1V5PA 5M4YB 5IRSA 5D3XA 4HB4B 4GXBA 1U5GA 3ODWA 4GMVA 3HIEA 1TXDA 5FI1A 3ODOA 2VSZA 3NWFA 1J0WA 3V5WA 3MDBC 3PVUA 2I1KA 3TFMA 4CYEA 1MK7B 2YRYA 2D11A 3ODXA 2VKIA 4ZRKA 1KI1B 1W1HA 5D27A 2DHJA 2YF0A 2YS5A 1NU2A 2ELBA 1K5GB 2Y8GA 5DHFB 1DDVA 2M14A 2D10A 1TJ6A 1Q67A 2EJ8A 3ML4A 2DYQA 4YL8A 4Z2MB 1XKEA 4TKNA 2DN6A 1DDMA 5C6RA 4A6FB 3PG7A 1BWNA 2CY4A 3HW2B 4ZRJA 2MWNB 4F7GA 3D8DA 1FAOA 1MAIA 2ADZA 1AWEA 3D8EA 2DX5A 4DX8A 3VOQA 5DH9B 2HTHB 5LOPB 2GCJA 5J3TA 2Z0OA 2UZSA 1I2HA 2KCJA 1X11A 4OSNA 4DXAB 2YVCA 3CXBB 3TW1A 5JHHA 2N23A 2DTCA 4CHMA 2GS0A 1OMWA 1P3RA 2YT2A 2GJYA 4ZRIA 2XQNM 2ZKMX 3AJ4A 3HQCA 1GG3A 2R09A 4GN1A 2AEHA 1PLSA 1BTNA 5HE3A 4EKUA 4CSQA 5C5BA 2VRWB 3PEGA 5HE0A 4P7IA 3DXCA 3SO6A 1OQNA 5JP4A 2OTXA 2I5FA 3A98B 2IYBA 3UZTA 1M7RA 1U2BA 4D6WA 2KUPA 1V89A 2D9YA 1FOEA 4HAVB 3X23A 4KHBB 1GC6A 3KSYA 5JLJB 4DBBA 1E5WA 2CODA 4MY6A 4KAXB 1NTYA 1SGHA 4IFSA 1U5EA 5HE1A 4HAYB 3CIKA 2D9WA 3ULBA 4D0NB 5HE2A 1PFJA 4A6KA 2DYNA 3NWDA 1WGQA
chains in the Genus database with same CATH topology
2RLOA 4K2PA 3FSSA 1W1GA 1FGZA 4WVFB 2LKOA 2MFQA 3A8QA 4HDOA 3DXDA 4F7HA 5DHAB 1ZC3B 1FHOA 2COFA 2L2IA 1Z87A 1P6SA 2LOXA 3GYPA 2DHKA 1QC6A 1RRPB 2DLWA 3AU5A 4PQ0A 4C0AA 2I1JA 2P0HA 4A6FA 2IFSA 2X18A 2K00A 1DDWA 1H4RA 1UEFA 1V5UA 3SV1A 1J19A 2CAYA 1DBHA 3PVWA 2DKPA 1X1GA 2YT1A 2Z0QA 3OANA 3PP2A 2ELAA 3FM8C 5C79A 2I5CA 2ZPYA 4NY0A 5C16A 2DKQA 1Y19B 5LONB 3QWMA 5D3VA 3NSUA 2DX1A 3PSCA 1V61A 2QKLA 1UNPA 2EMSA 3P7ZA 2P8VA 1K5DB 4EJNA 1NI2A 3KY9A 4HHVA 1P5TA 4CHJA 3BJIA 4YONA 4HAXB 3WYFB 4HAUB 5KCVA 2K2JA 4DX90 1EGXA 1X1FA 5FI0A 5GOWB 1LW3A 4WJ7A 4EMOA 2QKMA 1IRSA 2H7EA 1AQCA 1XR0B 4K2OA 3ZVRA 1NTVA 1EF1A 2D4QA 2LYDA 2MKRA 1UNQA 2M38A 2ROZB 3DXEA 1ZM0A 2RVBB 2LULA 4HATB 4GZUA 3PZDA 3RCPA 2Z0PA 1KZ7A 1DROA 2YSZA 3F0WA 2L1CA 2UZRA 1M7EA 3KRXA 2JP2A 5EFXA 4B6HA 1X86A 2MDXA 1SHCA 2D9VA 3MPXA 3KZ1A 4WSFA 2J59M 1MPHA 2LG1A 2DFKA 2D9XA 2W2WA 4HDQA 2E2XA 2V76A 3TO1A 5C5BB 4K17A 2J0KA 1H10A 2P0DA 2LOZA 2NZ8B 3IVFA 1QQGA 1FGYA 1U29A 3SUZA 3T06A 1XODA 3N7CA 1DYNA 2BCJA 5KQ4A 4H8SA 3SYXA 1ISNA 1XCGA 3QBVB 1UPRA 3TCAA 3KRWA 1U27A 4Z2NA 1FHWA 2KGXB 4HB2B 1Y5OA 1BTKA 3M1IB 2W2XD 1V88A 3SNHA 4HB0B 2DHIA 2HE7A 4IAPA 1UPQA 3WA0A 4NSWA 1RJ2A 2FJLA 4L6EA 4F7UP 4HB3B 3VIAA 5JHGA 1EVHA 5CLQB 4KVGB 2Q13A 4KHAA 3O96A 3HK0A 1MIXA 2CRFA 1GC7A 2YS3A 2D2QA 5J3QA 2RSGA 4K81A 1TQZA 4A5KA 3D8FA 3F5RA 3ULCA 2YT0A 5CLLB 3AU4A 2EMTA 1X05A 1N3HA 2EC1A 2ROVA 1WJMA 2K2UA 1WJ1A 1I7AA 3P6AA 1MIZB 1WVHA 1LB1A 4HAWB 4A6HA 5D3YA 2Y7BA 1U5DA 3U8ZA 2W2XC 2AL6A 2COAA 1KZGA 1V5MA 2P0FA 4Y94A 3LJUX 1PMSA 1FB8A 4PNKA 2Y8FA 1EAZA 3U7DA 1WGUA 4XWXA 4IOYX 4MT7A 2J0MA 5DIFB 3FEHA 2J0JA 1XD4A 5DI9B 1BAKA 3G9WA 2RNRB 1WG7A 3QIJA 2G35A 2CY5A 5KQ1A 2RGNB 1FHXA 1WI1A 1W1DA 1ZSQA 1MKEA 2R0DA 2H7DA 2PZ1A 2OQBA 2N0YA 2UVMA 3A8PA 2D9ZA 4GPTB 2NMBA 4HAZB 2RUKB 2COCA 4TYZA 3BINA 5J3YA 1MK9B 1OY2A 2DA0A 3GYOA 2GCLA 4KHOA 1ZC4B 1U5FA 4GMXB 4BBKA 5D3WA 4MK0A 3ZDTA 3PVLA 1B55A 1XX0A 1ZVRA 2YS1A 5L81A 1UNRA 3TVVA 1V5PA 5D3XA 4HB4B 4GXBA 1U5GA 3ODWA 4GMVA 1TXDA 5FI1A 3ODOA 2VSZA 1J0WA 3V5WA 3MDBC 3PVUA 2I1KA 3TFMA 4CYEA 1MK7B 2YRYA 2D11A 3ODXA 2VKIA 4ZRKA 1KI1B 1W1HA 5D27A 2DHJA 2YF0A 2YS5A 1NU2A 2ELBA 1K5GB 2Y8GA 5DHFB 1DDVA 2M14A 2D10A 1TJ6A 1Q67A 2EJ8A 3ML4A 2DYQA 4YL8A 4Z2MB 1XKEA 4TKNA 2DN6A 1DDMA 5C6RA 4A6FB 3PG7A 1BWNA 2CY4A 3HW2B 4ZRJA 2MWNB 4F7GA 3D8DA 1FAOA 1MAIA 2ADZA 1AWEA 3D8EA 2DX5A 4DX8A 3VOQA 5DH9B 2HTHB 5LOPB 2GCJA 5J3TA 2Z0OA 2UZSA 1I2HA 2KCJA 1X11A 4DXAB 2YVCA 3CXBB 3TW1A 5JHHA 2N23A 2DTCA 4CHMA 2GS0A 1OMWA 1P3RA 2GJYA 4ZRIA 2XQNM 3AJ4A 3HQCA 1GG3A 2R09A 4GN1A 2AEHA 1PLSA 1BTNA 5HE3A 4EKUA 5C5BA 2VRWB 3PEGA 5HE0A 4P7IA 3DXCA 3SO6A 1OQNA 5JP4A 2OTXA 2I5FA 3A98B 2IYBA 3UZTA 1M7RA 1U2BA 2KUPA 1V89A 2D9YA 1FOEA 4HAVB 3X23A 4KHBB 1GC6A 3KSYA 5JLJB 4DBBA 1E5WA 2CODA 4MY6A 4KAXB 1NTYA 1SGHA 4IFSA 1U5EA 5HE1A 4HAYB 3CIKA 2D9WA 3ULBA 4D0NB 5HE2A 1PFJA 4A6KA 2DYNA 1WGQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RLO A;  4K2P A;  3FSS A;  1W1G A;  1FGZ A;  4WVF B;  2LKO A;  2MFQ A;  3A8Q A;  4HDO A;  3DXD A;  4F7H A;  5DHA B;  1ZC3 B;  1FHO A;  2COF A;  2L2I A;  1Z87 A;  1P6S A;  2LOX A;  3GYP A;  2DHK A;  1QC6 A;  1RRP B;  2DLW A;  3AU5 A;  4PQ0 A;  4C0A A;  2I1J A;  2P0H A;  4A6F A;  2IFS A;  2X18 A;  2K00 A;  1DDW A;  1H4R A;  1UEF A;  1V5U A;  3SV1 A;  1J19 A;  2CAY A;  1DBH A;  3PVW A;  2DKP A;  1X1G A;  2YT1 A;  2Z0Q A;  3OAN A;  3PP2 A;  2ELA A;  3FM8 C;  5C79 A;  2I5C A;  2ZPY A;  4NY0 A;  5C16 A;  2DKQ A;  1Y19 B;  5LON B;  3QWM A;  5D3V A;  3NSU A;  2DX1 A;  3PSC A;  1V61 A;  2QKL A;  1UNP A;  2EMS A;  3P7Z A;  2P8V A;  1K5D B;  4EJN A;  1NI2 A;  3KY9 A;  4HHV A;  1P5T A;  4CHJ A;  3BJI A;  4YON A;  4HAX B;  3WYF B;  4HAU B;  5KCV A;  2K2J A;  4DX9 0;  1EGX A;  1X1F A;  5FI0 A;  5GOW B;  1LW3 A;  4WJ7 A;  4EMO A;  2QKM A;  1IRS A;  2H7E A;  1AQC A;  1XR0 B;  4K2O A;  3ZVR A;  1NTV A;  1EF1 A;  2D4Q A;  2LYD A;  2MKR A;  1UNQ A;  2M38 A;  2ROZ B;  3DXE A;  1ZM0 A;  2RVB B;  2LUL A;  4HAT B;  4GZU A;  3PZD A;  3RCP A;  2Z0P A;  1KZ7 A;  1DRO A;  2YSZ A;  3F0W A;  2L1C A;  2UZR A;  1M7E A;  3KRX A;  2JP2 A;  5EFX A;  4B6H A;  1X86 A;  2MDX A;  1SHC A;  2D9V A;  3MPX A;  3KZ1 A;  4WSF A;  2J59 M;  1MPH A;  2LG1 A;  2DFK A;  2D9X A;  2W2W A;  4HDQ A;  2E2X A;  2V76 A;  3TO1 A;  5C5B B;  4K17 A;  2J0K A;  1H10 A;  2P0D A;  2LOZ A;  2NZ8 B;  3IVF A;  1QQG A;  1FGY A;  1U29 A;  3SUZ A;  3T06 A;  1XOD A;  3N7C A;  1DYN A;  2BCJ A;  5KQ4 A;  4H8S A;  3SYX A;  1ISN A;  1XCG A;  3QBV B;  1UPR A;  3TCA A;  3KRW A;  1U27 A;  4Z2N A;  1FHW A;  2KGX B;  4HB2 B;  1Y5O A;  1BTK A;  3M1I B;  2W2X D;  1V88 A;  3SNH A;  4HB0 B;  2DHI A;  2HE7 A;  4IAP A;  1UPQ A;  3WA0 A;  4NSW A;  1RJ2 A;  2FJL A;  4L6E A;  4F7U P;  4HB3 B;  3VIA A;  5JHG A;  1EVH A;  5CLQ B;  4KVG B;  2Q13 A;  4KHA A;  3O96 A;  3HK0 A;  1MIX A;  2CRF A;  1GC7 A;  2YS3 A;  2D2Q A;  5J3Q A;  2RSG A;  4K81 A;  1TQZ A;  4A5K A;  3D8F A;  3F5R A;  3ULC A;  2YT0 A;  5CLL B;  3AU4 A;  2EMT A;  1X05 A;  1N3H A;  2EC1 A;  2ROV A;  1WJM A;  2K2U A;  1WJ1 A;  1I7A A;  3P6A A;  1MIZ B;  1WVH A;  1LB1 A;  4HAW B;  4A6H A;  5D3Y A;  2Y7B A;  1U5D A;  3U8Z A;  2W2X C;  2AL6 A;  2COA A;  1KZG A;  1V5M A;  2P0F A;  4Y94 A;  3LJU X;  1PMS A;  1FB8 A;  4PNK A;  2Y8F A;  1EAZ A;  3U7D A;  1WGU A;  4XWX A;  4IOY X;  4MT7 A;  2J0M A;  5DIF B;  3FEH A;  2J0J A;  1XD4 A;  5DI9 B;  1BAK A;  3G9W A;  2RNR B;  1WG7 A;  3QIJ A;  2G35 A;  2CY5 A;  5KQ1 A;  2RGN B;  1FHX A;  1WI1 A;  1W1D A;  1ZSQ A;  1MKE A;  2R0D A;  2H7D A;  2PZ1 A;  2OQB A;  2N0Y A;  2UVM A;  3A8P A;  2D9Z A;  4GPT B;  2NMB A;  4HAZ B;  2RUK B;  2COC A;  4TYZ A;  3BIN A;  5J3Y A;  1MK9 B;  1OY2 A;  2DA0 A;  3GYO A;  2GCL A;  4KHO A;  1ZC4 B;  1U5F A;  4GMX B;  4BBK A;  5D3W A;  4MK0 A;  3ZDT A;  3PVL A;  1B55 A;  1XX0 A;  1ZVR A;  2YS1 A;  5L81 A;  1UNR A;  3TVV A;  1V5P A;  5D3X A;  4HB4 B;  4GXB A;  1U5G A;  3ODW A;  4GMV A;  1TXD A;  5FI1 A;  3ODO A;  2VSZ A;  1J0W A;  3V5W A;  3MDB C;  3PVU A;  2I1K A;  3TFM A;  4CYE A;  1MK7 B;  2YRY A;  2D11 A;  3ODX A;  2VKI A;  4ZRK A;  1KI1 B;  1W1H A;  5D27 A;  2DHJ A;  2YF0 A;  2YS5 A;  1NU2 A;  2ELB A;  1K5G B;  2Y8G A;  5DHF B;  1DDV A;  2M14 A;  2D10 A;  1TJ6 A;  1Q67 A;  2EJ8 A;  3ML4 A;  2DYQ A;  4YL8 A;  4Z2M B;  1XKE A;  4TKN A;  2DN6 A;  1DDM A;  5C6R A;  4A6F B;  3PG7 A;  1BWN A;  2CY4 A;  3HW2 B;  4ZRJ A;  2MWN B;  4F7G A;  3D8D A;  1FAO A;  1MAI A;  2ADZ A;  1AWE A;  3D8E A;  2DX5 A;  4DX8 A;  3VOQ A;  5DH9 B;  2HTH B;  5LOP B;  2GCJ A;  5J3T A;  2Z0O A;  2UZS A;  1I2H A;  2KCJ A;  1X11 A;  4DXA B;  2YVC A;  3CXB B;  3TW1 A;  5JHH A;  2N23 A;  2DTC A;  4CHM A;  2GS0 A;  1OMW A;  1P3R A;  2GJY A;  4ZRI A;  2XQN M;  3AJ4 A;  3HQC A;  1GG3 A;  2R09 A;  4GN1 A;  2AEH A;  1PLS A;  1BTN A;  5HE3 A;  4EKU A;  5C5B A;  2VRW B;  3PEG A;  5HE0 A;  4P7I A;  3DXC A;  3SO6 A;  1OQN A;  5JP4 A;  2OTX A;  2I5F A;  3A98 B;  2IYB A;  3UZT A;  1M7R A;  1U2B A;  2KUP A;  1V89 A;  2D9Y A;  1FOE A;  4HAV B;  3X23 A;  4KHB B;  1GC6 A;  3KSY A;  5JLJ B;  4DBB A;  1E5W A;  2COD A;  4MY6 A;  4KAX B;  1NTY A;  1SGH A;  4IFS A;  1U5E A;  5HE1 A;  4HAY B;  3CIK A;  2D9W A;  3ULB A;  4D0N B;  5HE2 A;  1PFJ A;  4A6K A;  2DYN A;  1WGQ A; 
#chains in the Genus database with same CATH topology
 2RLO A;  5I2M A;  4K2P A;  3FSS A;  4QJ3 B;  1W1G A;  1FGZ A;  4WVF B;  2GUM A;  2LKO A;  2MFQ A;  3A8Q A;  4HDO A;  3DXD A;  4F7H A;  5DHA B;  1ZC3 B;  1FHO A;  2COF A;  2L2I A;  1Z87 A;  1P6S A;  2LOX A;  3GYP A;  2DHK A;  1QC6 A;  1RRP B;  2DLW A;  3AU5 A;  4PQ0 A;  4C0A A;  2I1J A;  2P0H A;  4A6F A;  2IFS A;  2X18 A;  2K00 A;  1DDW A;  1H4R A;  1UEF A;  1V5U A;  3SV1 A;  1J19 A;  2CAY A;  1DBH A;  3PVW A;  4GOU A;  2DKP A;  1X1G A;  2YT1 A;  2Z0Q A;  3OAN A;  3PP2 A;  2ELA A;  4GNK B;  2K8E A;  2Z4D A;  3FM8 C;  4OT1 A;  5C79 A;  2I5C A;  3NWA A;  2ZPY A;  4NY0 A;  5C16 A;  2DKQ A;  1ZYI A;  1Y19 B;  5LON B;  3QWM A;  5D3V A;  3NSU A;  2DX1 A;  3PSC A;  1V61 A;  2QKL A;  1UNP A;  2EMS A;  3P7Z A;  2P8V A;  2Z14 A;  1K5D B;  4EJN A;  1NI2 A;  2Z59 A;  3KY9 A;  4HHV A;  1P5T A;  4CHJ A;  3BJI A;  4YON A;  4HAX B;  3WYF B;  4HAU B;  5KCV A;  2K2J A;  1MI1 A;  4DX9 0;  1EGX A;  1X1F A;  5FI0 A;  5GOW B;  1LW3 A;  4WJ7 A;  4EMO A;  2QKM A;  1IRS A;  2H7E A;  1AQC A;  1XR0 B;  4K2O A;  3ZVR A;  1NTV A;  1EF1 A;  2D4Q A;  2LYD A;  2MKR A;  1UNQ A;  2M38 A;  2ROZ B;  3DXE A;  1ZM0 A;  2RVB B;  2LUL A;  4HAT B;  4GZU A;  3PZD A;  3RCP A;  2Z0P A;  1KZ7 A;  1DRO A;  2YSZ A;  3F0W A;  2L1C A;  2UZR A;  1M7E A;  3KRX A;  2JP2 A;  4L1R A;  5EFX A;  3DCX A;  4B6H A;  1X86 A;  2MDX A;  1SHC A;  2D9V A;  3MPX A;  3KZ1 A;  4WSF A;  4QXA B;  2J59 M;  1MPH A;  2LG1 A;  2DFK A;  2D9X A;  2W2W A;  4HDQ A;  2E2X A;  2V76 A;  3TO1 A;  5C5B B;  4K17 A;  2J0K A;  1H10 A;  2P0D A;  2LOZ A;  2NZ8 B;  3IVF A;  1QQG A;  1FGY A;  1U29 A;  3SUZ A;  3T06 A;  1XOD A;  3N7C A;  1DYN A;  2BCJ A;  5KQ4 A;  4H8S A;  3SYX A;  1ISN A;  1XCG A;  4DIX A;  3QBV B;  1UPR A;  3TCA A;  3KRW A;  1U27 A;  3B77 A;  4Z2N A;  2KR0 A;  1FHW A;  2KGX B;  4HB2 B;  1Y5O A;  1BTK A;  3M1I B;  2W2X D;  1V88 A;  3SNH A;  4HB0 B;  2DHI A;  2HE7 A;  4IAP A;  2KUQ A;  1UPQ A;  3WA0 A;  4NSW A;  1RJ2 A;  2FJL A;  4L6E A;  4F7U P;  2R2Y A;  4HB3 B;  3VIA A;  5JHG A;  1EVH A;  5CLQ B;  4KVG B;  2Q13 A;  4KHA A;  3O96 A;  3HK0 A;  1MIX A;  2CRF A;  1GC7 A;  2YS3 A;  2D2Q A;  5J3Q A;  2KIE A;  2RSG A;  4K81 A;  1TQZ A;  4A5K A;  1T77 A;  3D8F A;  3F5R A;  3ULC A;  2YT0 A;  5CLL B;  3AU4 A;  2EMT A;  1X05 A;  1N3H A;  2EC1 A;  2ROV A;  1WJM A;  2K2U A;  1WJ1 A;  1I7A A;  3P6A A;  1MIZ B;  1WVH A;  1LB1 A;  4HAW B;  4A6H A;  5LG4 B;  4QJ4 B;  5D3Y A;  2Y7B A;  1U5D A;  3U8Z A;  2W2X C;  3OHM B;  4HSI A;  2AL6 A;  2COA A;  4QJ5 B;  1KZG A;  1V5M A;  2P0F A;  4Y94 A;  3U12 A;  2FJU B;  3LJU X;  1PMS A;  1FB8 A;  4PNK A;  2Y8F A;  1EAZ A;  3U7D A;  1WGU A;  4XWX A;  4IOY X;  4MT7 A;  4KHB A;  2J0M A;  5DIF B;  3FEH A;  2NBV A;  3FVC A;  2J0J A;  1XD4 A;  5DI9 B;  1BAK A;  3G9W A;  3NW8 A;  2RNR B;  1WG7 A;  3QIJ A;  2G35 A;  2CY5 A;  2K49 A;  5KQ1 A;  2RGN B;  1FHX A;  1WI1 A;  3A58 A;  1W1D A;  1ZSQ A;  2Z13 A;  1MKE A;  2R0D A;  2H7D A;  2PZ1 A;  2OQB A;  2RRF A;  2N0Y A;  2UVM A;  3A8P A;  2D9Z A;  4GPT B;  2NMB A;  4HAZ B;  2RUK B;  2COC A;  4TYZ A;  3BIN A;  5J3Y A;  1MK9 B;  1OY2 A;  2DA0 A;  3GYO A;  2GCL A;  4KHO A;  1ZC4 B;  1U5F A;  3HSA A;  4GMX B;  4BBK A;  5D3W A;  4MK0 A;  3ZDT A;  3PVL A;  1B55 A;  1XX0 A;  1ZVR A;  5I2S A;  2KIG A;  2YS1 A;  5L81 A;  1UNR A;  3TVV A;  1V5P A;  5M4Y B;  5IRS A;  5D3X A;  4HB4 B;  4GXB A;  1U5G A;  3ODW A;  4GMV A;  3HIE A;  1TXD A;  5FI1 A;  3ODO A;  2VSZ A;  3NWF A;  1J0W A;  3V5W A;  3MDB C;  3PVU A;  2I1K A;  3TFM A;  4CYE A;  1MK7 B;  2YRY A;  2D11 A;  3ODX A;  2VKI A;  4ZRK A;  1KI1 B;  1W1H A;  5D27 A;  2DHJ A;  2YF0 A;  2YS5 A;  1NU2 A;  2ELB A;  1K5G B;  2Y8G A;  5DHF B;  1DDV A;  2M14 A;  2D10 A;  1TJ6 A;  1Q67 A;  2EJ8 A;  3ML4 A;  2DYQ A;  4YL8 A;  4Z2M B;  1XKE A;  4TKN A;  2DN6 A;  1DDM A;  5C6R A;  4A6F B;  3PG7 A;  1BWN A;  2CY4 A;  3HW2 B;  4ZRJ A;  2MWN B;  4F7G A;  3D8D A;  1FAO A;  1MAI A;  2ADZ A;  1AWE A;  3D8E A;  2DX5 A;  4DX8 A;  3VOQ A;  5DH9 B;  2HTH B;  5LOP B;  2GCJ A;  5J3T A;  2Z0O A;  2UZS A;  1I2H A;  2KCJ A;  1X11 A;  4OSN A;  4DXA B;  2YVC A;  3CXB B;  3TW1 A;  5JHH A;  2N23 A;  2DTC A;  4CHM A;  2GS0 A;  1OMW A;  1P3R A;  2YT2 A;  2GJY A;  4ZRI A;  2XQN M;  2ZKM X;  3AJ4 A;  3HQC A;  1GG3 A;  2R09 A;  4GN1 A;  2AEH A;  1PLS A;  1BTN A;  5HE3 A;  4EKU A;  4CSQ A;  5C5B A;  2VRW B;  3PEG A;  5HE0 A;  4P7I A;  3DXC A;  3SO6 A;  1OQN A;  5JP4 A;  2OTX A;  2I5F A;  3A98 B;  2IYB A;  3UZT A;  1M7R A;  1U2B A;  4D6W A;  2KUP A;  1V89 A;  2D9Y A;  1FOE A;  4HAV B;  3X23 A;  4KHB B;  1GC6 A;  3KSY A;  5JLJ B;  4DBB A;  1E5W A;  2COD A;  4MY6 A;  4KAX B;  1NTY A;  1SGH A;  4IFS A;  1U5E A;  5HE1 A;  4HAY B;  3CIK A;  2D9W A;  3ULB A;  4D0N B;  5HE2 A;  1PFJ A;  4A6K A;  2DYN A;  3NWD A;  1WGQ A; 
#chains in the Genus database with same CATH homology
 2RLO A;  4K2P A;  3FSS A;  1W1G A;  1FGZ A;  4WVF B;  2LKO A;  2MFQ A;  3A8Q A;  4HDO A;  3DXD A;  4F7H A;  5DHA B;  1ZC3 B;  1FHO A;  2COF A;  2L2I A;  1Z87 A;  1P6S A;  2LOX A;  3GYP A;  2DHK A;  1QC6 A;  1RRP B;  2DLW A;  3AU5 A;  4PQ0 A;  4C0A A;  2I1J A;  2P0H A;  4A6F A;  2IFS A;  2X18 A;  2K00 A;  1DDW A;  1H4R A;  1UEF A;  1V5U A;  3SV1 A;  1J19 A;  2CAY A;  1DBH A;  3PVW A;  2DKP A;  1X1G A;  2YT1 A;  2Z0Q A;  3OAN A;  3PP2 A;  2ELA A;  3FM8 C;  5C79 A;  2I5C A;  2ZPY A;  4NY0 A;  5C16 A;  2DKQ A;  1Y19 B;  5LON B;  3QWM A;  5D3V A;  3NSU A;  2DX1 A;  3PSC A;  1V61 A;  2QKL A;  1UNP A;  2EMS A;  3P7Z A;  2P8V A;  1K5D B;  4EJN A;  1NI2 A;  3KY9 A;  4HHV A;  1P5T A;  4CHJ A;  3BJI A;  4YON A;  4HAX B;  3WYF B;  4HAU B;  5KCV A;  2K2J A;  4DX9 0;  1EGX A;  1X1F A;  5FI0 A;  5GOW B;  1LW3 A;  4WJ7 A;  4EMO A;  2QKM A;  1IRS A;  2H7E A;  1AQC A;  1XR0 B;  4K2O A;  3ZVR A;  1NTV A;  1EF1 A;  2D4Q A;  2LYD A;  2MKR A;  1UNQ A;  2M38 A;  2ROZ B;  3DXE A;  1ZM0 A;  2RVB B;  2LUL A;  4HAT B;  4GZU A;  3PZD A;  3RCP A;  2Z0P A;  1KZ7 A;  1DRO A;  2YSZ A;  3F0W A;  2L1C A;  2UZR A;  1M7E A;  3KRX A;  2JP2 A;  5EFX A;  4B6H A;  1X86 A;  2MDX A;  1SHC A;  2D9V A;  3MPX A;  3KZ1 A;  4WSF A;  2J59 M;  1MPH A;  2LG1 A;  2DFK A;  2D9X A;  2W2W A;  4HDQ A;  2E2X A;  2V76 A;  3TO1 A;  5C5B B;  4K17 A;  2J0K A;  1H10 A;  2P0D A;  2LOZ A;  2NZ8 B;  3IVF A;  1QQG A;  1FGY A;  1U29 A;  3SUZ A;  3T06 A;  1XOD A;  3N7C A;  1DYN A;  2BCJ A;  5KQ4 A;  4H8S A;  3SYX A;  1ISN A;  1XCG A;  3QBV B;  1UPR A;  3TCA A;  3KRW A;  1U27 A;  4Z2N A;  1FHW A;  2KGX B;  4HB2 B;  1Y5O A;  1BTK A;  3M1I B;  2W2X D;  1V88 A;  3SNH A;  4HB0 B;  2DHI A;  2HE7 A;  4IAP A;  1UPQ A;  3WA0 A;  4NSW A;  1RJ2 A;  2FJL A;  4L6E A;  4F7U P;  4HB3 B;  3VIA A;  5JHG A;  1EVH A;  5CLQ B;  4KVG B;  2Q13 A;  4KHA A;  3O96 A;  3HK0 A;  1MIX A;  2CRF A;  1GC7 A;  2YS3 A;  2D2Q A;  5J3Q A;  2RSG A;  4K81 A;  1TQZ A;  4A5K A;  3D8F A;  3F5R A;  3ULC A;  2YT0 A;  5CLL B;  3AU4 A;  2EMT A;  1X05 A;  1N3H A;  2EC1 A;  2ROV A;  1WJM A;  2K2U A;  1WJ1 A;  1I7A A;  3P6A A;  1MIZ B;  1WVH A;  1LB1 A;  4HAW B;  4A6H A;  5D3Y A;  2Y7B A;  1U5D A;  3U8Z A;  2W2X C;  2AL6 A;  2COA A;  1KZG A;  1V5M A;  2P0F A;  4Y94 A;  3LJU X;  1PMS A;  1FB8 A;  4PNK A;  2Y8F A;  1EAZ A;  3U7D A;  1WGU A;  4XWX A;  4IOY X;  4MT7 A;  2J0M A;  5DIF B;  3FEH A;  2J0J A;  1XD4 A;  5DI9 B;  1BAK A;  3G9W A;  2RNR B;  1WG7 A;  3QIJ A;  2G35 A;  2CY5 A;  5KQ1 A;  2RGN B;  1FHX A;  1WI1 A;  1W1D A;  1ZSQ A;  1MKE A;  2R0D A;  2H7D A;  2PZ1 A;  2OQB A;  2N0Y A;  2UVM A;  3A8P A;  2D9Z A;  4GPT B;  2NMB A;  4HAZ B;  2RUK B;  2COC A;  4TYZ A;  3BIN A;  5J3Y A;  1MK9 B;  1OY2 A;  2DA0 A;  3GYO A;  2GCL A;  4KHO A;  1ZC4 B;  1U5F A;  4GMX B;  4BBK A;  5D3W A;  4MK0 A;  3ZDT A;  3PVL A;  1B55 A;  1XX0 A;  1ZVR A;  2YS1 A;  5L81 A;  1UNR A;  3TVV A;  1V5P A;  5D3X A;  4HB4 B;  4GXB A;  1U5G A;  3ODW A;  4GMV A;  1TXD A;  5FI1 A;  3ODO A;  2VSZ A;  1J0W A;  3V5W A;  3MDB C;  3PVU A;  2I1K A;  3TFM A;  4CYE A;  1MK7 B;  2YRY A;  2D11 A;  3ODX A;  2VKI A;  4ZRK A;  1KI1 B;  1W1H A;  5D27 A;  2DHJ A;  2YF0 A;  2YS5 A;  1NU2 A;  2ELB A;  1K5G B;  2Y8G A;  5DHF B;  1DDV A;  2M14 A;  2D10 A;  1TJ6 A;  1Q67 A;  2EJ8 A;  3ML4 A;  2DYQ A;  4YL8 A;  4Z2M B;  1XKE A;  4TKN A;  2DN6 A;  1DDM A;  5C6R A;  4A6F B;  3PG7 A;  1BWN A;  2CY4 A;  3HW2 B;  4ZRJ A;  2MWN B;  4F7G A;  3D8D A;  1FAO A;  1MAI A;  2ADZ A;  1AWE A;  3D8E A;  2DX5 A;  4DX8 A;  3VOQ A;  5DH9 B;  2HTH B;  5LOP B;  2GCJ A;  5J3T A;  2Z0O A;  2UZS A;  1I2H A;  2KCJ A;  1X11 A;  4DXA B;  2YVC A;  3CXB B;  3TW1 A;  5JHH A;  2N23 A;  2DTC A;  4CHM A;  2GS0 A;  1OMW A;  1P3R A;  2GJY A;  4ZRI A;  2XQN M;  3AJ4 A;  3HQC A;  1GG3 A;  2R09 A;  4GN1 A;  2AEH A;  1PLS A;  1BTN A;  5HE3 A;  4EKU A;  5C5B A;  2VRW B;  3PEG A;  5HE0 A;  4P7I A;  3DXC A;  3SO6 A;  1OQN A;  5JP4 A;  2OTX A;  2I5F A;  3A98 B;  2IYB A;  3UZT A;  1M7R A;  1U2B A;  2KUP A;  1V89 A;  2D9Y A;  1FOE A;  4HAV B;  3X23 A;  4KHB B;  1GC6 A;  3KSY A;  5JLJ B;  4DBB A;  1E5W A;  2COD A;  4MY6 A;  4KAX B;  1NTY A;  1SGH A;  4IFS A;  1U5E A;  5HE1 A;  4HAY B;  3CIK A;  2D9W A;  3ULB A;  4D0N B;  5HE2 A;  1PFJ A;  4A6K A;  2DYN A;  1WGQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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