2Z8JA

Crystal structure of escherichia coli gamma-glutamyltranspeptidase in complex with azaserine prepared in the dark
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
350
structure length
350
Chain Sequence
EDVFHPVRAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKKGDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of Escherichia coli gamma-glutamyltranspeptidase in complex with azaserine and acivicin: novel mechanistic implication for inhibition by glutamine antagonists
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Gamma-glutamyltranspeptidase
total genus 99
structure length 350
sequence length 350
chains with identical sequence C
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2007-09-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2z8jA02
3WHSA 4Z9OA 2DBWA 4GG2A 2QM6A 4ZC6A 3FNMA 4OTTA 2Z8KA 2E0YA 2NQOA 2V36A 3WHQA 4ZBKA 3WHRA 2DBUA 2QMCA 2Z8JA 4OTUA 2E0XA 2DBXA 4ZCGA 2Z8IA 5BPKA 2DG5A 5B5TA 4GDXA 3A75A
chains in the Genus database with same CATH superfamily
4ZBRA 1E7FA 1H5WA 2XVUA 2DYOA 2LXSA 2BXHA 2BXOA 2AJEA 4DM0A 2OZBB 2DBWA 5DQFA 1E7HA 3V08A 2ROHA 3GQXA 5DBYA 5IIHA 3LU6A 4J2VA 4E99A 1LNSA 2JUHA 3TDLA 3NVMA 4ZUXV 3FWCC 4OR0A 2KWFA 3H3AA 4W4UB 1FOUA 5IFOA 4BKEA 1VFIA 4N0FD 2DBUA 1O9XA 1AO6A 4OTUA 4PO0A 4M70B 2E0XA 3B9LA 2VUFA 2XVQA 2I2ZA 5GINA 2VUEA 3SIUB 5HOZA 4HGKA 4LB9A 5FUOA 1VZSA 3LU8A 5ID7A 4C31B 4OT2A 1E7IA 3A73A 3NMUA 4LB2A 5ID9A 4FK5B 1MIVA 2BXAA 4IW1A 4TQ1A 3VQIA 5GHKA 4S1YA 2BXDA 2DYMA 1KW2A 1E7EA 5IJ5A 1UORA 2K0NA 1KXPD 2BXBA 3GA9L 3MHHB 1GNJA 2LQHA 3WHQA 4F5UA 2XVVA 5IJEA 2BX8A 2EFCA 4N3ZA 2LQIA 4GDKB 2GUTA 3CX9A 3SIVB 3WHRA 4N0UD 4L9QA 2QMCA 4HGMB 4D7XA 3NVKA 4L8UA 1HK2A 3ICXA 2XMOA 1GNIA 2AGHB 1MIYA 4G04A 4LUHA 2I30A 1MUHA 1BM0A 4LUFA 4ZCGA 2LXTA 3JQZA 2DG5A 5BPKA 4IW2A 4GDXA 3A75A 4NAWB 2VDBA 4EMXA 3B9MA 1TF0A 3GQUA 2EFHA 4Z9OA 3M99C 4ZBQA 1HA2A 4BY9C 2QM6A 1E7BA 1BKEA 2OT3A 4OTTA 3ECPA 3KJLA 1N5UA 5IIUA 4TQ0A 2E0YA 1H9ZA 5IIXA 4FJCB 4ZBKA 1MA9A 3SQJA 1HK4A 3V03A 2BXIA 4DHXB 2BXKA 2Z8JA 3BPJA 4K71A 3FWBC 4WA6B 4MBEC 1LOTA 1TXUA 2BXFA 2XSIA 1E7AA 1E7CA 1HK5A 2BXQA 2DBXA 2KBZA 1E78A 2YDFA 2Z8IA 3LU7A 1J7EA 4LA0A 5B5TA 1MIWA 4ZC6A 1HK1A 3WHSA 3V09A 2BXGA 1J78A 3W1SA 1MUSA 2BXEA 4GG2A 3MHSB 3NVIA 2LOQA 3FNMA 4K2CA 2Z8KA 3PLAA 1NT2B 2NQOA 2V36A 2BXMA 1BJ5A 4F5SA 1MM8A 2XW1A 1JNBA 3H37A 5GIOA 5D7GA 2BXLA 3JRYA 4G01A 5IJFA 5GIPA 4F5TA 3KIKA 2EFEA 1HK3A 2XW0A 4FIPB 4JK4A 4G03A 1SB0A 2NNWA 2CKXA 4F5VA 4Z69A 2QHBA 2BXNA 2EFDA 2BXCA 4I9OA 1IJGA 3UIVA 2BXPA 4GDLB 3G9KD 4L9KA 2XVWA 1KDXA 1E7GA
chains in the Genus database with same CATH topology
4ZBRA 1E7FA 1H5WA 2XVUA 2DYOA 2BXHA 2BXOA 2AJEA 2OZBB 2DBWA 5DQFA 1E7HA 3V08A 2ROHA 3GQXA 5DBYA 5IIHA 3LU6A 4J2VA 4E99A 1LNSA 2JUHA 3TDLA 3NVMA 4ZUXV 3FWCC 4OR0A 3H3AA 4W4UB 1FOUA 5IFOA 4BKEA 1VFIA 4N0FD 2DBUA 1O9XA 1AO6A 4OTUA 4PO0A 4M70B 2E0XA 3B9LA 2VUFA 2XVQA 2I2ZA 5GINA 2VUEA 3SIUB 5HOZA 4HGKA 4LB9A 5FUOA 1VZSA 3LU8A 5ID7A 4C31B 4OT2A 1E7IA 3A73A 3NMUA 4LB2A 5ID9A 4FK5B 1MIVA 2BXAA 4IW1A 4TQ1A 3VQIA 5GHKA 4S1YA 2BXDA 2DYMA 1KW2A 1E7EA 5IJ5A 1UORA 3GA9L 1KXPD 2BXBA 3MHHB 3WHQA 1GNJA 4F5UA 2XVVA 5IJEA 2BX8A 2EFCA 4N3ZA 4GDKB 3CX9A 3SIVB 3WHRA 4N0UD 4L9QA 2QMCA 4HGMB 3NVKA 4L8UA 1HK2A 3ICXA 2XMOA 1GNIA 1MIYA 4G04A 4LUHA 2I30A 1BM0A 4LUFA 4ZCGA 3JQZA 2DG5A 5BPKA 4IW2A 4GDXA 3A75A 4NAWB 2VDBA 4EMXA 3B9MA 1TF0A 3GQUA 2EFHA 4Z9OA 3M99C 4ZBQA 1HA2A 4BY9C 2QM6A 1E7BA 1BKEA 2OT3A 4OTTA 3KJLA 1N5UA 5IIUA 4TQ0A 2E0YA 1H9ZA 5IIXA 4FJCB 4ZBKA 1MA9A 3SQJA 1HK4A 3V03A 2BXIA 4DHXB 2BXKA 2Z8JA 4K71A 3FWBC 4WA6B 4MBEC 1LOTA 1TXUA 2BXFA 2XSIA 1E7AA 1E7CA 1HK5A 2BXQA 2DBXA 2KBZA 1E78A 2YDFA 2Z8IA 3LU7A 1J7EA 4LA0A 5B5TA 1MIWA 4ZC6A 1HK1A 3WHSA 3V09A 2BXGA 1J78A 3W1SA 3NVIA 2BXEA 4GG2A 3MHSB 2LOQA 3FNMA 4K2CA 2Z8KA 3PLAA 1NT2B 2NQOA 2V36A 2BXMA 1BJ5A 4F5SA 2XW1A 1JNBA 3H37A 5GIOA 5D7GA 2BXLA 3JRYA 4G01A 5IJFA 5GIPA 4F5TA 3KIKA 2EFEA 1HK3A 2XW0A 4FIPB 4JK4A 4G03A 2NNWA 4F5VA 2CKXA 4Z69A 2QHBA 2BXNA 2EFDA 2BXCA 1IJGA 3UIVA 2BXPA 4GDLB 3G9KD 4L9KA 2XVWA 1E7GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WHS A;  4Z9O A;  2DBW A;  4GG2 A;  2QM6 A;  4ZC6 A;  3FNM A;  4OTT A;  2Z8K A;  2E0Y A;  2NQO A;  2V36 A;  3WHQ A;  4ZBK A;  3WHR A;  2DBU A;  2QMC A;  2Z8J A;  4OTU A;  2E0X A;  2DBX A;  4ZCG A;  2Z8I A;  5BPK A;  2DG5 A;  5B5T A;  4GDX A;  3A75 A; 
#chains in the Genus database with same CATH topology
 4ZBR A;  1E7F A;  1H5W A;  2XVU A;  2DYO A;  2LXS A;  2BXH A;  2BXO A;  2AJE A;  4DM0 A;  2OZB B;  2DBW A;  5DQF A;  1E7H A;  3V08 A;  2ROH A;  3GQX A;  5DBY A;  5IIH A;  3LU6 A;  4J2V A;  4E99 A;  1LNS A;  2JUH A;  3TDL A;  3NVM A;  4ZUX V;  3FWC C;  4OR0 A;  2KWF A;  3H3A A;  4W4U B;  1FOU A;  5IFO A;  4BKE A;  1VFI A;  4N0F D;  2DBU A;  1O9X A;  1AO6 A;  4OTU A;  4PO0 A;  4M70 B;  2E0X A;  3B9L A;  2VUF A;  2XVQ A;  2I2Z A;  5GIN A;  2VUE A;  3SIU B;  5HOZ A;  4HGK A;  4LB9 A;  5FUO A;  1VZS A;  3LU8 A;  5ID7 A;  4C31 B;  4OT2 A;  1E7I A;  3A73 A;  3NMU A;  4LB2 A;  5ID9 A;  4FK5 B;  1MIV A;  2BXA A;  4IW1 A;  4TQ1 A;  3VQI A;  5GHK A;  4S1Y A;  2BXD A;  2DYM A;  1KW2 A;  1E7E A;  5IJ5 A;  1UOR A;  2K0N A;  1KXP D;  2BXB A;  3GA9 L;  3MHH B;  1GNJ A;  2LQH A;  3WHQ A;  4F5U A;  2XVV A;  5IJE A;  2BX8 A;  2EFC A;  4N3Z A;  2LQI A;  4GDK B;  2GUT A;  3CX9 A;  3SIV B;  3WHR A;  4N0U D;  4L9Q A;  2QMC A;  4HGM B;  4D7X A;  3NVK A;  4L8U A;  1HK2 A;  3ICX A;  2XMO A;  1GNI A;  2AGH B;  1MIY A;  4G04 A;  4LUH A;  2I30 A;  1MUH A;  1BM0 A;  4LUF A;  4ZCG A;  2LXT A;  3JQZ A;  2DG5 A;  5BPK A;  4IW2 A;  4GDX A;  3A75 A;  4NAW B;  2VDB A;  4EMX A;  3B9M A;  1TF0 A;  3GQU A;  2EFH A;  4Z9O A;  3M99 C;  4ZBQ A;  1HA2 A;  4BY9 C;  2QM6 A;  1E7B A;  1BKE A;  2OT3 A;  4OTT A;  3ECP A;  3KJL A;  1N5U A;  5IIU A;  4TQ0 A;  2E0Y A;  1H9Z A;  5IIX A;  4FJC B;  4ZBK A;  1MA9 A;  3SQJ A;  1HK4 A;  3V03 A;  2BXI A;  4DHX B;  2BXK A;  2Z8J A;  3BPJ A;  4K71 A;  3FWB C;  4WA6 B;  4MBE C;  1LOT A;  1TXU A;  2BXF A;  2XSI A;  1E7A A;  1E7C A;  1HK5 A;  2BXQ A;  2DBX A;  2KBZ A;  1E78 A;  2YDF A;  2Z8I A;  3LU7 A;  1J7E A;  4LA0 A;  5B5T A;  1MIW A;  4ZC6 A;  1HK1 A;  3WHS A;  3V09 A;  2BXG A;  1J78 A;  3W1S A;  1MUS A;  2BXE A;  4GG2 A;  3MHS B;  3NVI A;  2LOQ A;  3FNM A;  4K2C A;  2Z8K A;  3PLA A;  1NT2 B;  2NQO A;  2V36 A;  2BXM A;  1BJ5 A;  4F5S A;  1MM8 A;  2XW1 A;  1JNB A;  3H37 A;  5GIO A;  5D7G A;  2BXL A;  3JRY A;  4G01 A;  5IJF A;  5GIP A;  4F5T A;  3KIK A;  2EFE A;  1HK3 A;  2XW0 A;  4FIP B;  4JK4 A;  4G03 A;  1SB0 A;  2NNW A;  2CKX A;  4F5V A;  4Z69 A;  2QHB A;  2BXN A;  2EFD A;  2BXC A;  4I9O A;  1IJG A;  3UIV A;  2BXP A;  4GDL B;  3G9K D;  4L9K A;  2XVW A;  1KDX A;  1E7G A; 
#chains in the Genus database with same CATH homology
 4ZBR A;  1E7F A;  1H5W A;  2XVU A;  2DYO A;  2BXH A;  2BXO A;  2AJE A;  2OZB B;  2DBW A;  5DQF A;  1E7H A;  3V08 A;  2ROH A;  3GQX A;  5DBY A;  5IIH A;  3LU6 A;  4J2V A;  4E99 A;  1LNS A;  2JUH A;  3TDL A;  3NVM A;  4ZUX V;  3FWC C;  4OR0 A;  3H3A A;  4W4U B;  1FOU A;  5IFO A;  4BKE A;  1VFI A;  4N0F D;  2DBU A;  1O9X A;  1AO6 A;  4OTU A;  4PO0 A;  4M70 B;  2E0X A;  3B9L A;  2VUF A;  2XVQ A;  2I2Z A;  5GIN A;  2VUE A;  3SIU B;  5HOZ A;  4HGK A;  4LB9 A;  5FUO A;  1VZS A;  3LU8 A;  5ID7 A;  4C31 B;  4OT2 A;  1E7I A;  3A73 A;  3NMU A;  4LB2 A;  5ID9 A;  4FK5 B;  1MIV A;  2BXA A;  4IW1 A;  4TQ1 A;  3VQI A;  5GHK A;  4S1Y A;  2BXD A;  2DYM A;  1KW2 A;  1E7E A;  5IJ5 A;  1UOR A;  3GA9 L;  1KXP D;  2BXB A;  3MHH B;  3WHQ A;  1GNJ A;  4F5U A;  2XVV A;  5IJE A;  2BX8 A;  2EFC A;  4N3Z A;  4GDK B;  3CX9 A;  3SIV B;  3WHR A;  4N0U D;  4L9Q A;  2QMC A;  4HGM B;  3NVK A;  4L8U A;  1HK2 A;  3ICX A;  2XMO A;  1GNI A;  1MIY A;  4G04 A;  4LUH A;  2I30 A;  1BM0 A;  4LUF A;  4ZCG A;  3JQZ A;  2DG5 A;  5BPK A;  4IW2 A;  4GDX A;  3A75 A;  4NAW B;  2VDB A;  4EMX A;  3B9M A;  1TF0 A;  3GQU A;  2EFH A;  4Z9O A;  3M99 C;  4ZBQ A;  1HA2 A;  4BY9 C;  2QM6 A;  1E7B A;  1BKE A;  2OT3 A;  4OTT A;  3KJL A;  1N5U A;  5IIU A;  4TQ0 A;  2E0Y A;  1H9Z A;  5IIX A;  4FJC B;  4ZBK A;  1MA9 A;  3SQJ A;  1HK4 A;  3V03 A;  2BXI A;  4DHX B;  2BXK A;  2Z8J A;  4K71 A;  3FWB C;  4WA6 B;  4MBE C;  1LOT A;  1TXU A;  2BXF A;  2XSI A;  1E7A A;  1E7C A;  1HK5 A;  2BXQ A;  2DBX A;  2KBZ A;  1E78 A;  2YDF A;  2Z8I A;  3LU7 A;  1J7E A;  4LA0 A;  5B5T A;  1MIW A;  4ZC6 A;  1HK1 A;  3WHS A;  3V09 A;  2BXG A;  1J78 A;  3W1S A;  3NVI A;  2BXE A;  4GG2 A;  3MHS B;  2LOQ A;  3FNM A;  4K2C A;  2Z8K A;  3PLA A;  1NT2 B;  2NQO A;  2V36 A;  2BXM A;  1BJ5 A;  4F5S A;  2XW1 A;  1JNB A;  3H37 A;  5GIO A;  5D7G A;  2BXL A;  3JRY A;  4G01 A;  5IJF A;  5GIP A;  4F5T A;  3KIK A;  2EFE A;  1HK3 A;  2XW0 A;  4FIP B;  4JK4 A;  4G03 A;  2NNW A;  4F5V A;  2CKX A;  4Z69 A;  2QHB A;  2BXN A;  2EFD A;  2BXC A;  1IJG A;  3UIV A;  2BXP A;  4GDL B;  3G9K D;  4L9K A;  2XVW A;  1E7G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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