2ZVMA

Crystal structure of pcna in complex with dna polymerase iota fragment
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
255
structure length
248
Chain Sequence
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Proliferating cell nuclear antigen
total genus 58
structure length 248
sequence length 255
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2008-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2zvmA00
3GGRC 1B8HA 1CZDA 1SXJF 3AIXB 3WGWA 1RWZA 1PLQA 2ZVWA 3AIXA 5JNED 3HI8A 5HACA 3V60B 3GGRB 3GGRA 3TBLA 2AWAA 1ISQA 3U61F 4TR6A 3FDSD 2IO4B 2ZVKA 3A2FB 4L6PA 2HIIB 2IO4A 5IXAA 3P87A 3G65C 4HK1A 2HIIA 3V62B 3U60F 4D2GA 2AVTA 1B77A 2ZVMA 3FDSC 5DAIA 3K4XA 2IJXA 3G65B 3I2MX 3G65A 3GPNA 5B7OA 2NTIC 3GPMA 1IZ5A 1RXZA 3V61B 3HSLX 2ZVVA 2NTIB 2NTIA 1YYPA 2OD8A 2IX2C 3F1WA 5A6DA 1U7BA 2Z0LA 3A1JC 1RXMA 2IX2B 2HIKC 4YHRA 4L60A 2IZOC 2IX2A 1AXCA 5H0TA 1PLRA 1VYJA 3AIZC 5AUJA 2HIKB 3A1JA 3LX2A 2IZOB 5E0UA 2HIKA 1W60A 3P91A 3VKXA 1UL1A 3U5ZF 5E0TA 1T6LA 3LX1A 1DMLA 3AIZA 1VYMA 5CFKA 4CS5A 1U76A 2HIIC 1GE8A 1UD9A 3P83A 2ZVLA 5DA7A 3A1JB 5IY4A 4RJFA 4ZTDA 5IWDA 3IFVA 5E0VA 1IZ4A
chains in the Genus database with same CATH superfamily
3GGRC 1B8HA 1CZDA 1SXJF 3AIXB 3WGWA 1RWZA 1PLQA 2ZVWA 3AIXA 5JNED 3HI8A 5HACA 3V60B 3GGRB 3GGRA 3TBLA 2AWAA 1ISQA 3U61F 4TR6A 3FDSD 2IO4B 2ZVKA 3A2FB 4L6PA 2HIIB 2IO4A 5IXAA 3P87A 3G65C 4HK1A 2HIIA 3V62B 3U60F 4D2GA 2AVTA 1B77A 2ZVMA 3FDSC 5DAIA 3K4XA 2IJXA 3G65B 3I2MX 3G65A 3GPNA 5B7OA 2NTIC 3GPMA 1IZ5A 1RXZA 3V61B 3HSLX 2ZVVA 2NTIB 2NTIA 1YYPA 2OD8A 2IX2C 3F1WA 5A6DA 1U7BA 2Z0LA 3A1JC 1RXMA 2IX2B 2HIKC 4YHRA 4L60A 2IZOC 2IX2A 1AXCA 5H0TA 1PLRA 1VYJA 3AIZC 5AUJA 2HIKB 3A1JA 3LX2A 2IZOB 5E0UA 2HIKA 1W60A 3P91A 3VKXA 1UL1A 3U5ZF 5E0TA 1T6LA 3LX1A 1DMLA 3AIZA 1VYMA 5CFKA 4CS5A 1U76A 2HIIC 1GE8A 1UD9A 3P83A 2ZVLA 5DA7A 3A1JB 5IY4A 4RJFA 4ZTDA 5IWDA 3IFVA 5E0VA 1IZ4A
chains in the Genus database with same CATH topology
3GGRC 1B8HA 1CZDA 1SXJF 3AIXB 3WGWA 1RWZA 1PLQA 2ZVWA 3AIXA 5JNED 3HI8A 5HACA 3V60B 3GGRB 3GGRA 3TBLA 2AWAA 1ISQA 3U61F 4TR6A 3FDSD 2IO4B 2ZVKA 3A2FB 4L6PA 2HIIB 2IO4A 5IXAA 3P87A 3G65C 4HK1A 2HIIA 3V62B 3U60F 4D2GA 2AVTA 1B77A 2ZVMA 3FDSC 5DAIA 3K4XA 2IJXA 3G65B 3I2MX 3G65A 3GPNA 5B7OA 2NTIC 3GPMA 1IZ5A 1RXZA 3V61B 3HSLX 2ZVVA 2NTIB 2NTIA 1YYPA 2OD8A 2IX2C 3F1WA 5A6DA 1U7BA 2Z0LA 3A1JC 1RXMA 2IX2B 2HIKC 4YHRA 4L60A 2IZOC 2IX2A 1AXCA 5H0TA 1PLRA 1VYJA 3AIZC 5AUJA 2HIKB 3A1JA 3LX2A 2IZOB 5E0UA 2HIKA 1W60A 3P91A 3VKXA 1UL1A 3U5ZF 5E0TA 1T6LA 3LX1A 1DMLA 3AIZA 1VYMA 5CFKA 4CS5A 1U76A 2HIIC 1GE8A 1UD9A 3P83A 2ZVLA 5DA7A 3A1JB 5IY4A 4RJFA 4ZTDA 5IWDA 3IFVA 5E0VA 1IZ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GGR C;  1B8H A;  1CZD A;  1SXJ F;  3AIX B;  3WGW A;  1RWZ A;  1PLQ A;  2ZVW A;  3AIX A;  5JNE D;  3HI8 A;  5HAC A;  3V60 B;  3GGR B;  3GGR A;  3TBL A;  2AWA A;  1ISQ A;  3U61 F;  4TR6 A;  3FDS D;  2IO4 B;  2ZVK A;  3A2F B;  4L6P A;  2HII B;  2IO4 A;  5IXA A;  3P87 A;  3G65 C;  4HK1 A;  2HII A;  3V62 B;  3U60 F;  4D2G A;  2AVT A;  1B77 A;  2ZVM A;  3FDS C;  5DAI A;  3K4X A;  2IJX A;  3G65 B;  3I2M X;  3G65 A;  3GPN A;  5B7O A;  2NTI C;  3GPM A;  1IZ5 A;  1RXZ A;  3V61 B;  3HSL X;  2ZVV A;  2NTI B;  2NTI A;  1YYP A;  2OD8 A;  2IX2 C;  3F1W A;  5A6D A;  1U7B A;  2Z0L A;  3A1J C;  1RXM A;  2IX2 B;  2HIK C;  4YHR A;  4L60 A;  2IZO C;  2IX2 A;  1AXC A;  5H0T A;  1PLR A;  1VYJ A;  3AIZ C;  5AUJ A;  2HIK B;  3A1J A;  3LX2 A;  2IZO B;  5E0U A;  2HIK A;  1W60 A;  3P91 A;  3VKX A;  1UL1 A;  3U5Z F;  5E0T A;  1T6L A;  3LX1 A;  1DML A;  3AIZ A;  1VYM A;  5CFK A;  4CS5 A;  1U76 A;  2HII C;  1GE8 A;  1UD9 A;  3P83 A;  2ZVL A;  5DA7 A;  3A1J B;  5IY4 A;  4RJF A;  4ZTD A;  5IWD A;  3IFV A;  5E0V A;  1IZ4 A; 
#chains in the Genus database with same CATH topology
 3GGR C;  1B8H A;  1CZD A;  1SXJ F;  3AIX B;  3WGW A;  1RWZ A;  1PLQ A;  2ZVW A;  3AIX A;  5JNE D;  3HI8 A;  5HAC A;  3V60 B;  3GGR B;  3GGR A;  3TBL A;  2AWA A;  1ISQ A;  3U61 F;  4TR6 A;  3FDS D;  2IO4 B;  2ZVK A;  3A2F B;  4L6P A;  2HII B;  2IO4 A;  5IXA A;  3P87 A;  3G65 C;  4HK1 A;  2HII A;  3V62 B;  3U60 F;  4D2G A;  2AVT A;  1B77 A;  2ZVM A;  3FDS C;  5DAI A;  3K4X A;  2IJX A;  3G65 B;  3I2M X;  3G65 A;  3GPN A;  5B7O A;  2NTI C;  3GPM A;  1IZ5 A;  1RXZ A;  3V61 B;  3HSL X;  2ZVV A;  2NTI B;  2NTI A;  1YYP A;  2OD8 A;  2IX2 C;  3F1W A;  5A6D A;  1U7B A;  2Z0L A;  3A1J C;  1RXM A;  2IX2 B;  2HIK C;  4YHR A;  4L60 A;  2IZO C;  2IX2 A;  1AXC A;  5H0T A;  1PLR A;  1VYJ A;  3AIZ C;  5AUJ A;  2HIK B;  3A1J A;  3LX2 A;  2IZO B;  5E0U A;  2HIK A;  1W60 A;  3P91 A;  3VKX A;  1UL1 A;  3U5Z F;  5E0T A;  1T6L A;  3LX1 A;  1DML A;  3AIZ A;  1VYM A;  5CFK A;  4CS5 A;  1U76 A;  2HII C;  1GE8 A;  1UD9 A;  3P83 A;  2ZVL A;  5DA7 A;  3A1J B;  5IY4 A;  4RJF A;  4ZTD A;  5IWD A;  3IFV A;  5E0V A;  1IZ4 A; 
#chains in the Genus database with same CATH homology
 3GGR C;  1B8H A;  1CZD A;  1SXJ F;  3AIX B;  3WGW A;  1RWZ A;  1PLQ A;  2ZVW A;  3AIX A;  5JNE D;  3HI8 A;  5HAC A;  3V60 B;  3GGR B;  3GGR A;  3TBL A;  2AWA A;  1ISQ A;  3U61 F;  4TR6 A;  3FDS D;  2IO4 B;  2ZVK A;  3A2F B;  4L6P A;  2HII B;  2IO4 A;  5IXA A;  3P87 A;  3G65 C;  4HK1 A;  2HII A;  3V62 B;  3U60 F;  4D2G A;  2AVT A;  1B77 A;  2ZVM A;  3FDS C;  5DAI A;  3K4X A;  2IJX A;  3G65 B;  3I2M X;  3G65 A;  3GPN A;  5B7O A;  2NTI C;  3GPM A;  1IZ5 A;  1RXZ A;  3V61 B;  3HSL X;  2ZVV A;  2NTI B;  2NTI A;  1YYP A;  2OD8 A;  2IX2 C;  3F1W A;  5A6D A;  1U7B A;  2Z0L A;  3A1J C;  1RXM A;  2IX2 B;  2HIK C;  4YHR A;  4L60 A;  2IZO C;  2IX2 A;  1AXC A;  5H0T A;  1PLR A;  1VYJ A;  3AIZ C;  5AUJ A;  2HIK B;  3A1J A;  3LX2 A;  2IZO B;  5E0U A;  2HIK A;  1W60 A;  3P91 A;  3VKX A;  1UL1 A;  3U5Z F;  5E0T A;  1T6L A;  3LX1 A;  1DML A;  3AIZ A;  1VYM A;  5CFK A;  4CS5 A;  1U76 A;  2HII C;  1GE8 A;  1UD9 A;  3P83 A;  2ZVL A;  5DA7 A;  3A1J B;  5IY4 A;  4RJF A;  4ZTD A;  5IWD A;  3IFV A;  5E0V A;  1IZ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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