3A2FB

Crystal structure of pyrococcus furiosus dna polymerase/pcna monomer mutant complex
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
247
structure length
247
Chain Sequence
PFEIVFEGAKEFAQLIDTASKLIDEAAFKVTEDGISMRAMDPSRVVLIDLNLPSSIFSKYEVVEPETIGVNLDHLKKILKRGKAKDTLILKKGEENFLEITIQGTATRTFRVPLIDVEEMEVDLPELPFTAKVVVLGEVLKAAVKAASLVSDSIKFIARENEFIMKAEGETQEVEIKLTLEDEGLLDIEVQEETKSAYGVSYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLTFLLAPRVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex
rcsb
molecule keywords DNA polymerase
molecule tags Transferase/replication
source organism Pyrococcus furiosus
total genus 52
structure length 247
sequence length 247
ec nomenclature
pdb deposition date 2009-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
B PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 3a2fB00
1UL1A 3A2FB 1CZDA 5HACA 1YYPA 3FDSD 4RJFA 1VYJA 2HIKA 4YHRA 2ZVLA 1U76A 1VYMA 2HIKC 4CS5A 1RXZA 3TBLA 3I2MX 3GPNA 1PLQA 5E0UA 3GGRC 3U60F 2HIIA 2AWAA 5IXAA 3HSLX 2IJXA 2ZVMA 3AIZC 2NTIC 5E0TA 4TR6A 3G65C 3GGRB 3A1JB 1DMLA 5CFKA 3FDSC 3P83A 5IWDA 5AUJA 2NTIB 3GPMA 3P87A 3P91A 3V62B 1AXCA 1B8HA 3G65B 3V60B 1RWZA 1IZ5A 4L6PA 2IZOC 3AIXA 3U5ZF 2HIIC 2HIKB 4D2GA 1IZ4A 5JNED 3F1WA 2ZVWA 3K4XA 1ISQA 2IO4A 1W60A 5B7OA 5IY4A 5E0VA 2IX2A 5A6DA 1UD9A 3LX2A 3A1JA 5DAIA 2IX2C 1T6LA 1SXJF 5H0TA 1U7BA 2ZVKA 1GE8A 1B77A 4HK1A 3V61B 1RXMA 2Z0LA 3U61F 2OD8A 1PLRA 4L60A 2IZOB 2ZVVA 2HIIB 3AIXB 3HI8A 3WGWA 3IFVA 3GGRA 3LX1A 4ZTDA 2AVTA 3A1JC 2IO4B 3AIZA 3VKXA 2NTIA 5DA7A 3G65A 2IX2B
chains in the Genus database with same CATH superfamily
1UL1A 3A2FB 1CZDA 5HACA 1YYPA 3FDSD 4RJFA 1VYJA 2HIKA 4YHRA 2ZVLA 1U76A 1VYMA 2HIKC 4CS5A 1RXZA 3TBLA 3I2MX 3GPNA 1PLQA 5E0UA 3GGRC 3U60F 2HIIA 2AWAA 5IXAA 3HSLX 2IJXA 2ZVMA 3AIZC 2NTIC 5E0TA 4TR6A 3G65C 3GGRB 3A1JB 1DMLA 5CFKA 3FDSC 3P83A 5IWDA 5AUJA 2NTIB 3GPMA 3P87A 3P91A 3V62B 1AXCA 1B8HA 3G65B 3V60B 1RWZA 1IZ5A 4L6PA 2IZOC 3AIXA 3U5ZF 2HIIC 2HIKB 4D2GA 1IZ4A 5JNED 3F1WA 2ZVWA 3K4XA 1ISQA 2IO4A 1W60A 5B7OA 5IY4A 5E0VA 2IX2A 5A6DA 1UD9A 3LX2A 3A1JA 5DAIA 2IX2C 1T6LA 1SXJF 5H0TA 1U7BA 2ZVKA 1GE8A 1B77A 4HK1A 3V61B 1RXMA 2Z0LA 3U61F 2OD8A 1PLRA 4L60A 2IZOB 2ZVVA 2HIIB 3AIXB 3HI8A 3WGWA 3IFVA 3GGRA 3LX1A 4ZTDA 2AVTA 3A1JC 2IO4B 3AIZA 3VKXA 2NTIA 5DA7A 3G65A 2IX2B
chains in the Genus database with same CATH topology
1UL1A 3A2FB 1CZDA 5HACA 1YYPA 3FDSD 4RJFA 1VYJA 2HIKA 4YHRA 2ZVLA 1U76A 1VYMA 2HIKC 4CS5A 1RXZA 3TBLA 3I2MX 3GPNA 1PLQA 5E0UA 3GGRC 3U60F 2HIIA 2AWAA 5IXAA 3HSLX 2IJXA 2ZVMA 3AIZC 2NTIC 5E0TA 4TR6A 3G65C 3GGRB 3A1JB 1DMLA 5CFKA 3FDSC 3P83A 5IWDA 5AUJA 2NTIB 3GPMA 3P87A 3P91A 3V62B 1AXCA 1B8HA 3G65B 3V60B 1RWZA 1IZ5A 4L6PA 2IZOC 3AIXA 3U5ZF 2HIIC 2HIKB 4D2GA 1IZ4A 5JNED 3F1WA 2ZVWA 3K4XA 1ISQA 2IO4A 1W60A 5B7OA 5IY4A 5E0VA 2IX2A 5A6DA 1UD9A 3LX2A 3A1JA 5DAIA 2IX2C 1T6LA 1SXJF 5H0TA 1U7BA 2ZVKA 1GE8A 1B77A 4HK1A 3V61B 1RXMA 2Z0LA 3U61F 2OD8A 1PLRA 4L60A 2IZOB 2ZVVA 2HIIB 3AIXB 3HI8A 3WGWA 3IFVA 3GGRA 3LX1A 4ZTDA 2AVTA 3A1JC 2IO4B 3AIZA 3VKXA 2NTIA 5DA7A 3G65A 2IX2B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UL1 A;  3A2F B;  1CZD A;  5HAC A;  1YYP A;  3FDS D;  4RJF A;  1VYJ A;  2HIK A;  4YHR A;  2ZVL A;  1U76 A;  1VYM A;  2HIK C;  4CS5 A;  1RXZ A;  3TBL A;  3I2M X;  3GPN A;  1PLQ A;  5E0U A;  3GGR C;  3U60 F;  2HII A;  2AWA A;  5IXA A;  3HSL X;  2IJX A;  2ZVM A;  3AIZ C;  2NTI C;  5E0T A;  4TR6 A;  3G65 C;  3GGR B;  3A1J B;  1DML A;  5CFK A;  3FDS C;  3P83 A;  5IWD A;  5AUJ A;  2NTI B;  3GPM A;  3P87 A;  3P91 A;  3V62 B;  1AXC A;  1B8H A;  3G65 B;  3V60 B;  1RWZ A;  1IZ5 A;  4L6P A;  2IZO C;  3AIX A;  3U5Z F;  2HII C;  2HIK B;  4D2G A;  1IZ4 A;  5JNE D;  3F1W A;  2ZVW A;  3K4X A;  1ISQ A;  2IO4 A;  1W60 A;  5B7O A;  5IY4 A;  5E0V A;  2IX2 A;  5A6D A;  1UD9 A;  3LX2 A;  3A1J A;  5DAI A;  2IX2 C;  1T6L A;  1SXJ F;  5H0T A;  1U7B A;  2ZVK A;  1GE8 A;  1B77 A;  4HK1 A;  3V61 B;  1RXM A;  2Z0L A;  3U61 F;  2OD8 A;  1PLR A;  4L60 A;  2IZO B;  2ZVV A;  2HII B;  3AIX B;  3HI8 A;  3WGW A;  3IFV A;  3GGR A;  3LX1 A;  4ZTD A;  2AVT A;  3A1J C;  2IO4 B;  3AIZ A;  3VKX A;  2NTI A;  5DA7 A;  3G65 A;  2IX2 B; 
#chains in the Genus database with same CATH topology
 1UL1 A;  3A2F B;  1CZD A;  5HAC A;  1YYP A;  3FDS D;  4RJF A;  1VYJ A;  2HIK A;  4YHR A;  2ZVL A;  1U76 A;  1VYM A;  2HIK C;  4CS5 A;  1RXZ A;  3TBL A;  3I2M X;  3GPN A;  1PLQ A;  5E0U A;  3GGR C;  3U60 F;  2HII A;  2AWA A;  5IXA A;  3HSL X;  2IJX A;  2ZVM A;  3AIZ C;  2NTI C;  5E0T A;  4TR6 A;  3G65 C;  3GGR B;  3A1J B;  1DML A;  5CFK A;  3FDS C;  3P83 A;  5IWD A;  5AUJ A;  2NTI B;  3GPM A;  3P87 A;  3P91 A;  3V62 B;  1AXC A;  1B8H A;  3G65 B;  3V60 B;  1RWZ A;  1IZ5 A;  4L6P A;  2IZO C;  3AIX A;  3U5Z F;  2HII C;  2HIK B;  4D2G A;  1IZ4 A;  5JNE D;  3F1W A;  2ZVW A;  3K4X A;  1ISQ A;  2IO4 A;  1W60 A;  5B7O A;  5IY4 A;  5E0V A;  2IX2 A;  5A6D A;  1UD9 A;  3LX2 A;  3A1J A;  5DAI A;  2IX2 C;  1T6L A;  1SXJ F;  5H0T A;  1U7B A;  2ZVK A;  1GE8 A;  1B77 A;  4HK1 A;  3V61 B;  1RXM A;  2Z0L A;  3U61 F;  2OD8 A;  1PLR A;  4L60 A;  2IZO B;  2ZVV A;  2HII B;  3AIX B;  3HI8 A;  3WGW A;  3IFV A;  3GGR A;  3LX1 A;  4ZTD A;  2AVT A;  3A1J C;  2IO4 B;  3AIZ A;  3VKX A;  2NTI A;  5DA7 A;  3G65 A;  2IX2 B; 
#chains in the Genus database with same CATH homology
 1UL1 A;  3A2F B;  1CZD A;  5HAC A;  1YYP A;  3FDS D;  4RJF A;  1VYJ A;  2HIK A;  4YHR A;  2ZVL A;  1U76 A;  1VYM A;  2HIK C;  4CS5 A;  1RXZ A;  3TBL A;  3I2M X;  3GPN A;  1PLQ A;  5E0U A;  3GGR C;  3U60 F;  2HII A;  2AWA A;  5IXA A;  3HSL X;  2IJX A;  2ZVM A;  3AIZ C;  2NTI C;  5E0T A;  4TR6 A;  3G65 C;  3GGR B;  3A1J B;  1DML A;  5CFK A;  3FDS C;  3P83 A;  5IWD A;  5AUJ A;  2NTI B;  3GPM A;  3P87 A;  3P91 A;  3V62 B;  1AXC A;  1B8H A;  3G65 B;  3V60 B;  1RWZ A;  1IZ5 A;  4L6P A;  2IZO C;  3AIX A;  3U5Z F;  2HII C;  2HIK B;  4D2G A;  1IZ4 A;  5JNE D;  3F1W A;  2ZVW A;  3K4X A;  1ISQ A;  2IO4 A;  1W60 A;  5B7O A;  5IY4 A;  5E0V A;  2IX2 A;  5A6D A;  1UD9 A;  3LX2 A;  3A1J A;  5DAI A;  2IX2 C;  1T6L A;  1SXJ F;  5H0T A;  1U7B A;  2ZVK A;  1GE8 A;  1B77 A;  4HK1 A;  3V61 B;  1RXM A;  2Z0L A;  3U61 F;  2OD8 A;  1PLR A;  4L60 A;  2IZO B;  2ZVV A;  2HII B;  3AIX B;  3HI8 A;  3WGW A;  3IFV A;  3GGR A;  3LX1 A;  4ZTD A;  2AVT A;  3A1J C;  2IO4 B;  3AIZ A;  3VKX A;  2NTI A;  5DA7 A;  3G65 A;  2IX2 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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