3A5LS

Crystal structure of a dictyostelium p109a mg2+-actin in complex with human gelsolin segment 1
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
123
structure length
123
Chain Sequence
VEHPEFLKAGKEPGLQIWRVEKFDLVPVPTCLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
pubmed doi rcsb
molecule tags Contractile protein
source organism Homo sapiens
molecule keywords Gelsolin
total genus 38
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2009-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 3a5lS00
1H1VG 4PKGG 3EGXB 2VIKA 3FG6A 5DD2A 3CIPG 5HVKD 4PKIG 1CNUA 1KCQA 2HD7A 3EGDA 1SVYA 3FG7A 5FAEA 1M4JA 1M2OA 5KYXA 1ESVS 2FH4A 1X67A 2W0IA 2QTVA 4CBXG 1WFSA 5KYYB 3FFKA 4JD2H 1T3XA 1EQYS 1F7SA 4KEEA 3EFOB 1C0FS 2MV2A 2MP4A 2VACA 1TMWA 2KVKA 4KEFA 5KYUB 4BEX1 5KYNA 3L50A 5KYYA 2XFAA 2NUPB 3CJCG 2LLFA 1T2LA 2D8BA 3EFOA 1NM1G 3CI5G 1MDUA 3TU5B 4LIZA 1SVRA 5KYUA 1PD0A 2I2QA 2NUPA 3A5NS 1TVJA 1AK7A 4S10C 3EGXA 3CJBG 1VKKA 5L6WC 3FFNA 1PD1A 1PCXA 1QPVA 1AHQA 1NMDG 5HVKB 1JHWA 1V6FA 1RGIG 3Q2BA 1YAGG 1M2VB 3A5MS 2NUTB 1T3YA 1YVNG 2FH1A 1SVQA 1VFQA 1CFYA 3EH2A 5A1MA 1COFA 2VILA 2XF1A 2NUTA 1WNJA 1DEJS 3DAWB 2L72A 1UDMA 1AK6A 4CBUG 1WM4A 5FAFA 3EGDB 2FF6G 1C0GS 2LXXA 5KYXB 1HQZ1 2FH2A 2LJ8A 2FF3A 1D4XG 1P8ZG 1P8XA 2FGHA 4PKHB 1T44G 1J72A 1D0NA 1NPHA 4Z94G 4CBWG 2FH3A 2MOTA 3EH1A 3EG9B 3A5LS 1M2VA 5IVUA 1NLVG 5KYWB 4KEDA 3A5OS 3EG9A 1Q8GA 1Q8XA 5KYWA
chains in the Genus database with same CATH superfamily
1H1VG 4PKGG 3EGXB 2VIKA 3FG6A 5DD2A 3CIPG 5HVKD 4PKIG 1CNUA 1KCQA 2HD7A 3EGDA 1SVYA 3FG7A 5FAEA 1M4JA 1M2OA 5KYXA 1ESVS 2FH4A 1X67A 2W0IA 2QTVA 4CBXG 1WFSA 5KYYB 3FFKA 4JD2H 1T3XA 1EQYS 1F7SA 4KEEA 3EFOB 1C0FS 2MV2A 2MP4A 2VACA 1TMWA 2KVKA 4KEFA 5KYUB 4BEX1 5KYNA 3L50A 5KYYA 2XFAA 2NUPB 3CJCG 2LLFA 1T2LA 2D8BA 3EFOA 1NM1G 3CI5G 1MDUA 3TU5B 4LIZA 1SVRA 5KYUA 1PD0A 2I2QA 2NUPA 3A5NS 1TVJA 1AK7A 4S10C 3EGXA 3CJBG 1VKKA 5L6WC 3FFNA 1PD1A 1PCXA 1QPVA 1AHQA 1NMDG 5HVKB 1JHWA 1V6FA 1RGIG 3Q2BA 1YAGG 1M2VB 3A5MS 2NUTB 1T3YA 1YVNG 2FH1A 1SVQA 1VFQA 1CFYA 3EH2A 5A1MA 1COFA 2VILA 2XF1A 2NUTA 1WNJA 1DEJS 3DA7A 3DAWB 2L72A 1UDMA 1AK6A 4CBUG 1WM4A 5FAFA 3EGDB 2FF6G 1C0GS 2LXXA 5KYXB 1HQZ1 2FH2A 2LJ8A 2FF3A 1D4XG 1P8ZG 1P8XA 2FGHA 4PKHB 1T44G 1J72A 1D0NA 1NPHA 4Z94G 4CBWG 2FH3A 2MOTA 3EH1A 3EG9B 3A5LS 1M2VA 5IVUA 1NLVG 5KYWB 4KEDA 3A5OS 3EG9A 1Q8GA 1Q8XA 5KYWA
chains in the Genus database with same CATH topology
1H1VG 4PKGG 3EGXB 2VIKA 3FG6A 5DD2A 3CIPG 5HVKD 4PKIG 1CNUA 1KCQA 2HD7A 3EGDA 1SVYA 3FG7A 5FAEA 1M4JA 1M2OA 5KYXA 1ESVS 2FH4A 1X67A 2W0IA 2QTVA 4CBXG 1WFSA 5KYYB 3FFKA 4JD2H 1T3XA 1EQYS 1F7SA 4KEEA 3EFOB 1C0FS 2MV2A 2MP4A 2VACA 1TMWA 2KVKA 4KEFA 5KYUB 4BEX1 5KYNA 3L50A 5KYYA 2XFAA 2NUPB 3CJCG 2LLFA 1T2LA 2D8BA 3EFOA 1NM1G 3CI5G 1MDUA 3TU5B 4LIZA 1SVRA 5KYUA 1PD0A 2I2QA 2NUPA 3A5NS 1TVJA 1AK7A 4S10C 3EGXA 3CJBG 1VKKA 5L6WC 3FFNA 1PD1A 1PCXA 1QPVA 1AHQA 1NMDG 5HVKB 1JHWA 1V6FA 1RGIG 3Q2BA 1YAGG 1M2VB 3A5MS 2NUTB 1T3YA 1YVNG 2FH1A 1SVQA 1VFQA 1CFYA 3EH2A 5A1MA 1COFA 2VILA 2XF1A 2NUTA 1WNJA 1DEJS 3DA7A 3DAWB 2L72A 1UDMA 1AK6A 4CBUG 1WM4A 5FAFA 3EGDB 2FF6G 1C0GS 2LXXA 5KYXB 1HQZ1 2FH2A 2LJ8A 2FF3A 1D4XG 1P8ZG 1P8XA 2FGHA 4PKHB 1T44G 1J72A 1D0NA 1NPHA 4Z94G 4CBWG 2FH3A 2MOTA 3EH1A 3EG9B 3A5LS 1M2VA 5IVUA 1NLVG 5KYWB 4KEDA 3A5OS 3EG9A 1Q8GA 1Q8XA 5KYWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1H1V G;  4PKG G;  3EGX B;  2VIK A;  3FG6 A;  5DD2 A;  3CIP G;  5HVK D;  4PKI G;  1CNU A;  1KCQ A;  2HD7 A;  3EGD A;  1SVY A;  3FG7 A;  5FAE A;  1M4J A;  1M2O A;  5KYX A;  1ESV S;  2FH4 A;  1X67 A;  2W0I A;  2QTV A;  4CBX G;  1WFS A;  5KYY B;  3FFK A;  4JD2 H;  1T3X A;  1EQY S;  1F7S A;  4KEE A;  3EFO B;  1C0F S;  2MV2 A;  2MP4 A;  2VAC A;  1TMW A;  2KVK A;  4KEF A;  5KYU B;  4BEX 1;  5KYN A;  3L50 A;  5KYY A;  2XFA A;  2NUP B;  3CJC G;  2LLF A;  1T2L A;  2D8B A;  3EFO A;  1NM1 G;  3CI5 G;  1MDU A;  3TU5 B;  4LIZ A;  1SVR A;  5KYU A;  1PD0 A;  2I2Q A;  2NUP A;  3A5N S;  1TVJ A;  1AK7 A;  4S10 C;  3EGX A;  3CJB G;  1VKK A;  5L6W C;  3FFN A;  1PD1 A;  1PCX A;  1QPV A;  1AHQ A;  1NMD G;  5HVK B;  1JHW A;  1V6F A;  1RGI G;  3Q2B A;  1YAG G;  1M2V B;  3A5M S;  2NUT B;  1T3Y A;  1YVN G;  2FH1 A;  1SVQ A;  1VFQ A;  1CFY A;  3EH2 A;  5A1M A;  1COF A;  2VIL A;  2XF1 A;  2NUT A;  1WNJ A;  1DEJ S;  3DAW B;  2L72 A;  1UDM A;  1AK6 A;  4CBU G;  1WM4 A;  5FAF A;  3EGD B;  2FF6 G;  1C0G S;  2LXX A;  5KYX B;  1HQZ 1;  2FH2 A;  2LJ8 A;  2FF3 A;  1D4X G;  1P8Z G;  1P8X A;  2FGH A;  4PKH B;  1T44 G;  1J72 A;  1D0N A;  1NPH A;  4Z94 G;  4CBW G;  2FH3 A;  2MOT A;  3EH1 A;  3EG9 B;  3A5L S;  1M2V A;  5IVU A;  1NLV G;  5KYW B;  4KED A;  3A5O S;  3EG9 A;  1Q8G A;  1Q8X A;  5KYW A; 
#chains in the Genus database with same CATH topology
 1H1V G;  4PKG G;  3EGX B;  2VIK A;  3FG6 A;  5DD2 A;  3CIP G;  5HVK D;  4PKI G;  1CNU A;  1KCQ A;  2HD7 A;  3EGD A;  1SVY A;  3FG7 A;  5FAE A;  1M4J A;  1M2O A;  5KYX A;  1ESV S;  2FH4 A;  1X67 A;  2W0I A;  2QTV A;  4CBX G;  1WFS A;  5KYY B;  3FFK A;  4JD2 H;  1T3X A;  1EQY S;  1F7S A;  4KEE A;  3EFO B;  1C0F S;  2MV2 A;  2MP4 A;  2VAC A;  1TMW A;  2KVK A;  4KEF A;  5KYU B;  4BEX 1;  5KYN A;  3L50 A;  5KYY A;  2XFA A;  2NUP B;  3CJC G;  2LLF A;  1T2L A;  2D8B A;  3EFO A;  1NM1 G;  3CI5 G;  1MDU A;  3TU5 B;  4LIZ A;  1SVR A;  5KYU A;  1PD0 A;  2I2Q A;  2NUP A;  3A5N S;  1TVJ A;  1AK7 A;  4S10 C;  3EGX A;  3CJB G;  1VKK A;  5L6W C;  3FFN A;  1PD1 A;  1PCX A;  1QPV A;  1AHQ A;  1NMD G;  5HVK B;  1JHW A;  1V6F A;  1RGI G;  3Q2B A;  1YAG G;  1M2V B;  3A5M S;  2NUT B;  1T3Y A;  1YVN G;  2FH1 A;  1SVQ A;  1VFQ A;  1CFY A;  3EH2 A;  5A1M A;  1COF A;  2VIL A;  2XF1 A;  2NUT A;  1WNJ A;  1DEJ S;  3DA7 A;  3DAW B;  2L72 A;  1UDM A;  1AK6 A;  4CBU G;  1WM4 A;  5FAF A;  3EGD B;  2FF6 G;  1C0G S;  2LXX A;  5KYX B;  1HQZ 1;  2FH2 A;  2LJ8 A;  2FF3 A;  1D4X G;  1P8Z G;  1P8X A;  2FGH A;  4PKH B;  1T44 G;  1J72 A;  1D0N A;  1NPH A;  4Z94 G;  4CBW G;  2FH3 A;  2MOT A;  3EH1 A;  3EG9 B;  3A5L S;  1M2V A;  5IVU A;  1NLV G;  5KYW B;  4KED A;  3A5O S;  3EG9 A;  1Q8G A;  1Q8X A;  5KYW A; 
#chains in the Genus database with same CATH homology
 1H1V G;  4PKG G;  3EGX B;  2VIK A;  3FG6 A;  5DD2 A;  3CIP G;  5HVK D;  4PKI G;  1CNU A;  1KCQ A;  2HD7 A;  3EGD A;  1SVY A;  3FG7 A;  5FAE A;  1M4J A;  1M2O A;  5KYX A;  1ESV S;  2FH4 A;  1X67 A;  2W0I A;  2QTV A;  4CBX G;  1WFS A;  5KYY B;  3FFK A;  4JD2 H;  1T3X A;  1EQY S;  1F7S A;  4KEE A;  3EFO B;  1C0F S;  2MV2 A;  2MP4 A;  2VAC A;  1TMW A;  2KVK A;  4KEF A;  5KYU B;  4BEX 1;  5KYN A;  3L50 A;  5KYY A;  2XFA A;  2NUP B;  3CJC G;  2LLF A;  1T2L A;  2D8B A;  3EFO A;  1NM1 G;  3CI5 G;  1MDU A;  3TU5 B;  4LIZ A;  1SVR A;  5KYU A;  1PD0 A;  2I2Q A;  2NUP A;  3A5N S;  1TVJ A;  1AK7 A;  4S10 C;  3EGX A;  3CJB G;  1VKK A;  5L6W C;  3FFN A;  1PD1 A;  1PCX A;  1QPV A;  1AHQ A;  1NMD G;  5HVK B;  1JHW A;  1V6F A;  1RGI G;  3Q2B A;  1YAG G;  1M2V B;  3A5M S;  2NUT B;  1T3Y A;  1YVN G;  2FH1 A;  1SVQ A;  1VFQ A;  1CFY A;  3EH2 A;  5A1M A;  1COF A;  2VIL A;  2XF1 A;  2NUT A;  1WNJ A;  1DEJ S;  3DA7 A;  3DAW B;  2L72 A;  1UDM A;  1AK6 A;  4CBU G;  1WM4 A;  5FAF A;  3EGD B;  2FF6 G;  1C0G S;  2LXX A;  5KYX B;  1HQZ 1;  2FH2 A;  2LJ8 A;  2FF3 A;  1D4X G;  1P8Z G;  1P8X A;  2FGH A;  4PKH B;  1T44 G;  1J72 A;  1D0N A;  1NPH A;  4Z94 G;  4CBW G;  2FH3 A;  2MOT A;  3EH1 A;  3EG9 B;  3A5L S;  1M2V A;  5IVU A;  1NLV G;  5KYW B;  4KED A;  3A5O S;  3EG9 A;  1Q8G A;  1Q8X A;  5KYW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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