3A5MS

Crystal structure of a dictyostelium p109i mg2+-actin in complex with human gelsolin segment 1
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
123
structure length
123
Chain Sequence
VEHPEFLKAGKEPGLQIWRVEKFDLVPVPTCLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
pubmed doi rcsb
molecule tags Contractile protein
source organism Homo sapiens
molecule keywords Gelsolin
total genus 38
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2009-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 3a5mS00
3CIPG 2W0IA 3EG9B 5DD2A 4CBXG 5IVUA 2LLFA 1VKKA 1NM1G 2D8BA 4PKGG 5FAFA 1H1VG 1NMDG 1Q8XA 2NUTA 1T3YA 3EH2A 2XFAA 2VIKA 3CI5G 5KYYA 5FAEA 3EGDB 1T2LA 4LIZA 1T44G 1D4XG 1Q8GA 2FH3A 2KVKA 1C0FS 3EFOA 3EGXB 3FFNA 1P8XA 1HQZ1 2HD7A 2LXXA 1NPHA 3A5MS 1CFYA 1PD0A 1SVRA 1YAGG 1AHQA 2I2QA 2VACA 2VILA 2NUTB 2NUPA 1DEJS 2NUPB 2XF1A 3A5OS 2FF3A 5KYUA 4CBWG 5KYYB 1WM4A 1PD1A 2L72A 4PKHB 1SVQA 4KEFA 1VFQA 5A1MA 5L6WC 1CNUA 2FGHA 5KYWA 3EFOB 1M2VA 1ESVS 2FH2A 3FG7A 3L50A 1C0GS 1P8ZG 1QPVA 1AK6A 2QTVA 1TMWA 2LJ8A 3TU5B 3DAWB 3Q2BA 1AK7A 4KEDA 4CBUG 3A5LS 5KYXA 1SVYA 5HVKD 3EH1A 1F7SA 5KYUB 2MP4A 3EG9A 2FF6G 1NLVG 4Z94G 1KCQA 3FFKA 1WFSA 1COFA 3CJCG 3A5NS 5KYWB 1M2VB 3FG6A 2FH1A 1UDMA 5HVKB 1J72A 1EQYS 3EGDA 1D0NA 2MV2A 1M2OA 4S10C 3CJBG 1V6FA 1WNJA 4JD2H 1TVJA 1RGIG 1YVNG 1JHWA 2MOTA 1M4JA 4PKIG 5KYNA 4KEEA 1MDUA 5KYXB 3EGXA 1T3XA 1PCXA 2FH4A 1X67A 4BEX1
chains in the Genus database with same CATH superfamily
3CIPG 2W0IA 3EG9B 5DD2A 4CBXG 5IVUA 2LLFA 1VKKA 1NM1G 2D8BA 4PKGG 5FAFA 1H1VG 1NMDG 1Q8XA 2NUTA 1T3YA 3EH2A 2XFAA 2VIKA 3CI5G 5KYYA 5FAEA 3EGDB 1T2LA 4LIZA 1T44G 1D4XG 1Q8GA 2FH3A 2KVKA 1C0FS 3EFOA 3EGXB 3FFNA 1P8XA 1HQZ1 3DA7A 2HD7A 2LXXA 1NPHA 3A5MS 1CFYA 1PD0A 1SVRA 1YAGG 1AHQA 2I2QA 2VACA 2VILA 2NUTB 2NUPA 1DEJS 2NUPB 2XF1A 3A5OS 2FF3A 5KYUA 4CBWG 5KYYB 1WM4A 1PD1A 2L72A 4PKHB 1SVQA 4KEFA 1VFQA 5A1MA 5L6WC 1CNUA 2FGHA 5KYWA 3EFOB 1M2VA 1ESVS 2FH2A 3FG7A 3L50A 1C0GS 1P8ZG 1QPVA 1AK6A 2QTVA 1TMWA 2LJ8A 3TU5B 3DAWB 3Q2BA 1AK7A 4KEDA 4CBUG 3A5LS 5KYXA 1SVYA 5HVKD 3EH1A 1F7SA 5KYUB 2MP4A 3EG9A 2FF6G 1NLVG 4Z94G 1KCQA 3FFKA 1WFSA 1COFA 3CJCG 3A5NS 5KYWB 1M2VB 3FG6A 2FH1A 1UDMA 5HVKB 1J72A 1EQYS 3EGDA 1D0NA 2MV2A 1M2OA 4S10C 3CJBG 1V6FA 1WNJA 4JD2H 1TVJA 1RGIG 1YVNG 1JHWA 2MOTA 1M4JA 4PKIG 5KYNA 4KEEA 1MDUA 5KYXB 3EGXA 1T3XA 1PCXA 2FH4A 1X67A 4BEX1
chains in the Genus database with same CATH topology
3CIPG 2W0IA 3EG9B 5DD2A 4CBXG 5IVUA 2LLFA 1VKKA 1NM1G 2D8BA 4PKGG 5FAFA 1H1VG 1NMDG 1Q8XA 2NUTA 1T3YA 3EH2A 2XFAA 2VIKA 3CI5G 5KYYA 5FAEA 3EGDB 1T2LA 4LIZA 1T44G 1D4XG 1Q8GA 2FH3A 2KVKA 1C0FS 3EFOA 3EGXB 3FFNA 1P8XA 1HQZ1 3DA7A 2HD7A 2LXXA 1NPHA 3A5MS 1CFYA 1PD0A 1SVRA 1YAGG 1AHQA 2I2QA 2VACA 2VILA 2NUTB 2NUPA 1DEJS 2NUPB 2XF1A 3A5OS 2FF3A 5KYUA 4CBWG 5KYYB 1WM4A 1PD1A 2L72A 4PKHB 1SVQA 4KEFA 1VFQA 5A1MA 5L6WC 1CNUA 2FGHA 5KYWA 3EFOB 1M2VA 1ESVS 2FH2A 3FG7A 3L50A 1C0GS 1P8ZG 1QPVA 1AK6A 2QTVA 1TMWA 2LJ8A 3TU5B 3DAWB 3Q2BA 1AK7A 4KEDA 4CBUG 3A5LS 5KYXA 1SVYA 5HVKD 3EH1A 1F7SA 5KYUB 2MP4A 3EG9A 2FF6G 1NLVG 4Z94G 1KCQA 3FFKA 1WFSA 1COFA 3CJCG 3A5NS 5KYWB 1M2VB 3FG6A 2FH1A 1UDMA 5HVKB 1J72A 1EQYS 3EGDA 1D0NA 2MV2A 1M2OA 4S10C 3CJBG 1V6FA 1WNJA 4JD2H 1TVJA 1RGIG 1YVNG 1JHWA 2MOTA 1M4JA 4PKIG 5KYNA 4KEEA 1MDUA 5KYXB 3EGXA 1T3XA 1PCXA 2FH4A 1X67A 4BEX1
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CIP G;  2W0I A;  3EG9 B;  5DD2 A;  4CBX G;  5IVU A;  2LLF A;  1VKK A;  1NM1 G;  2D8B A;  4PKG G;  5FAF A;  1H1V G;  1NMD G;  1Q8X A;  2NUT A;  1T3Y A;  3EH2 A;  2XFA A;  2VIK A;  3CI5 G;  5KYY A;  5FAE A;  3EGD B;  1T2L A;  4LIZ A;  1T44 G;  1D4X G;  1Q8G A;  2FH3 A;  2KVK A;  1C0F S;  3EFO A;  3EGX B;  3FFN A;  1P8X A;  1HQZ 1;  2HD7 A;  2LXX A;  1NPH A;  3A5M S;  1CFY A;  1PD0 A;  1SVR A;  1YAG G;  1AHQ A;  2I2Q A;  2VAC A;  2VIL A;  2NUT B;  2NUP A;  1DEJ S;  2NUP B;  2XF1 A;  3A5O S;  2FF3 A;  5KYU A;  4CBW G;  5KYY B;  1WM4 A;  1PD1 A;  2L72 A;  4PKH B;  1SVQ A;  4KEF A;  1VFQ A;  5A1M A;  5L6W C;  1CNU A;  2FGH A;  5KYW A;  3EFO B;  1M2V A;  1ESV S;  2FH2 A;  3FG7 A;  3L50 A;  1C0G S;  1P8Z G;  1QPV A;  1AK6 A;  2QTV A;  1TMW A;  2LJ8 A;  3TU5 B;  3DAW B;  3Q2B A;  1AK7 A;  4KED A;  4CBU G;  3A5L S;  5KYX A;  1SVY A;  5HVK D;  3EH1 A;  1F7S A;  5KYU B;  2MP4 A;  3EG9 A;  2FF6 G;  1NLV G;  4Z94 G;  1KCQ A;  3FFK A;  1WFS A;  1COF A;  3CJC G;  3A5N S;  5KYW B;  1M2V B;  3FG6 A;  2FH1 A;  1UDM A;  5HVK B;  1J72 A;  1EQY S;  3EGD A;  1D0N A;  2MV2 A;  1M2O A;  4S10 C;  3CJB G;  1V6F A;  1WNJ A;  4JD2 H;  1TVJ A;  1RGI G;  1YVN G;  1JHW A;  2MOT A;  1M4J A;  4PKI G;  5KYN A;  4KEE A;  1MDU A;  5KYX B;  3EGX A;  1T3X A;  1PCX A;  2FH4 A;  1X67 A;  4BEX 1; 
#chains in the Genus database with same CATH topology
 3CIP G;  2W0I A;  3EG9 B;  5DD2 A;  4CBX G;  5IVU A;  2LLF A;  1VKK A;  1NM1 G;  2D8B A;  4PKG G;  5FAF A;  1H1V G;  1NMD G;  1Q8X A;  2NUT A;  1T3Y A;  3EH2 A;  2XFA A;  2VIK A;  3CI5 G;  5KYY A;  5FAE A;  3EGD B;  1T2L A;  4LIZ A;  1T44 G;  1D4X G;  1Q8G A;  2FH3 A;  2KVK A;  1C0F S;  3EFO A;  3EGX B;  3FFN A;  1P8X A;  1HQZ 1;  3DA7 A;  2HD7 A;  2LXX A;  1NPH A;  3A5M S;  1CFY A;  1PD0 A;  1SVR A;  1YAG G;  1AHQ A;  2I2Q A;  2VAC A;  2VIL A;  2NUT B;  2NUP A;  1DEJ S;  2NUP B;  2XF1 A;  3A5O S;  2FF3 A;  5KYU A;  4CBW G;  5KYY B;  1WM4 A;  1PD1 A;  2L72 A;  4PKH B;  1SVQ A;  4KEF A;  1VFQ A;  5A1M A;  5L6W C;  1CNU A;  2FGH A;  5KYW A;  3EFO B;  1M2V A;  1ESV S;  2FH2 A;  3FG7 A;  3L50 A;  1C0G S;  1P8Z G;  1QPV A;  1AK6 A;  2QTV A;  1TMW A;  2LJ8 A;  3TU5 B;  3DAW B;  3Q2B A;  1AK7 A;  4KED A;  4CBU G;  3A5L S;  5KYX A;  1SVY A;  5HVK D;  3EH1 A;  1F7S A;  5KYU B;  2MP4 A;  3EG9 A;  2FF6 G;  1NLV G;  4Z94 G;  1KCQ A;  3FFK A;  1WFS A;  1COF A;  3CJC G;  3A5N S;  5KYW B;  1M2V B;  3FG6 A;  2FH1 A;  1UDM A;  5HVK B;  1J72 A;  1EQY S;  3EGD A;  1D0N A;  2MV2 A;  1M2O A;  4S10 C;  3CJB G;  1V6F A;  1WNJ A;  4JD2 H;  1TVJ A;  1RGI G;  1YVN G;  1JHW A;  2MOT A;  1M4J A;  4PKI G;  5KYN A;  4KEE A;  1MDU A;  5KYX B;  3EGX A;  1T3X A;  1PCX A;  2FH4 A;  1X67 A;  4BEX 1; 
#chains in the Genus database with same CATH homology
 3CIP G;  2W0I A;  3EG9 B;  5DD2 A;  4CBX G;  5IVU A;  2LLF A;  1VKK A;  1NM1 G;  2D8B A;  4PKG G;  5FAF A;  1H1V G;  1NMD G;  1Q8X A;  2NUT A;  1T3Y A;  3EH2 A;  2XFA A;  2VIK A;  3CI5 G;  5KYY A;  5FAE A;  3EGD B;  1T2L A;  4LIZ A;  1T44 G;  1D4X G;  1Q8G A;  2FH3 A;  2KVK A;  1C0F S;  3EFO A;  3EGX B;  3FFN A;  1P8X A;  1HQZ 1;  3DA7 A;  2HD7 A;  2LXX A;  1NPH A;  3A5M S;  1CFY A;  1PD0 A;  1SVR A;  1YAG G;  1AHQ A;  2I2Q A;  2VAC A;  2VIL A;  2NUT B;  2NUP A;  1DEJ S;  2NUP B;  2XF1 A;  3A5O S;  2FF3 A;  5KYU A;  4CBW G;  5KYY B;  1WM4 A;  1PD1 A;  2L72 A;  4PKH B;  1SVQ A;  4KEF A;  1VFQ A;  5A1M A;  5L6W C;  1CNU A;  2FGH A;  5KYW A;  3EFO B;  1M2V A;  1ESV S;  2FH2 A;  3FG7 A;  3L50 A;  1C0G S;  1P8Z G;  1QPV A;  1AK6 A;  2QTV A;  1TMW A;  2LJ8 A;  3TU5 B;  3DAW B;  3Q2B A;  1AK7 A;  4KED A;  4CBU G;  3A5L S;  5KYX A;  1SVY A;  5HVK D;  3EH1 A;  1F7S A;  5KYU B;  2MP4 A;  3EG9 A;  2FF6 G;  1NLV G;  4Z94 G;  1KCQ A;  3FFK A;  1WFS A;  1COF A;  3CJC G;  3A5N S;  5KYW B;  1M2V B;  3FG6 A;  2FH1 A;  1UDM A;  5HVK B;  1J72 A;  1EQY S;  3EGD A;  1D0N A;  2MV2 A;  1M2O A;  4S10 C;  3CJB G;  1V6F A;  1WNJ A;  4JD2 H;  1TVJ A;  1RGI G;  1YVN G;  1JHW A;  2MOT A;  1M4J A;  4PKI G;  5KYN A;  4KEE A;  1MDU A;  5KYX B;  3EGX A;  1T3X A;  1PCX A;  2FH4 A;  1X67 A;  4BEX 1; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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