3AA0A

Crystal structure of actin capping protein in complex with the cp-binding motif derived from carmil
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
270
structure length
270
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
pubmed doi rcsb
source organism Gallus gallus
molecule tags Protein binding
molecule keywords F-actin-capping protein subunit alpha-1
total genus 88
structure length 270
sequence length 270
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3aa0A01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3aa0A02
3LK2A 2KZ7A 3LK2B 3AA1A 3AA1B 3LK42 5ADXL 3AAAA 3AAAB 5AFUK 3AAEA 3AAEB 3LK41 4AKRA 4AKRB 3AA0A 3AA0B 3AA7A 3AA7B 3LK3A 1IZNA 1IZNB 3LK3B 5AFUL 2KXPB 2KXPA 5ADXK 3AA6A 3AA6B 2KZ7B
chains in the Genus database with same CATH superfamily
5DL7A 1ZHZA 3VY9X 4CTDA 4RLBA 3POQA 2Y0LA 4KRAA 2R88A 4QQ1A 2Y0HA 4FQEA 1KNCA 2LHFA 2XTQA 4GCQA 2FGQX 2OUWA 2FGRA 3UAQA 2JQYA 4C00A 3A2SX 4AYNA 4FSPA 2Q0TA 1MPFA 1PRNA 2YNKA 4FOZA 4AYEC 5B66O 3RBHA 3AAEB 1ZHWA 3EMNX 1T1LA 3DA3A 5EE2A 3TZGA 4C69X 4E1SA 2R4PA 3T20A 2M07A 4FRTA 3AA0B 2LFUA 4LSEA 4RJXA 5GTIO 4BUMX 1HXUA 1ME5A 1IZNA 3PRNA 4FZNA 3UPGA 1BH3A 2Y2XA 3LVYA 2MNHA 4AZLA 4FZMA 5ADXK 1GFNA 1LW1A 1QJ8A 2XE5A 2AF7A 1S5LO 2YPVA 3AA6B 4PR7A 5H2FO 2KZ7A 4G76A 2KC0A 2X9KA 3JCUO 2Y0KA 4C4VB 3AA1B 3HOLA 2JN8A 5KAIO 4N58A 3KZIO 5DL5A 2ODJA 2QTKA 3DWOX 3WU2O 3PQSA 3KVDD 4KR4A 4K3CA 1P4TA 4RJWA 4XNKA 4U9CA 3DZMA 4O3YA 2PORA 3QRCA 1GFMA 5T5FA 4FMSA 4GCPA 4FRXA 2ZFGA 4FT6A 3VZTX 5PRNA 4PUXA 4GCSA 2JMMA 3PGRA 3VE1A 5G3AA 1HXXA 1ZHYA 3D7IA 2ZLDA 3VY8X 4AKRB 4D65A 3LK3A 3GP6A 4KR8A 5KAFO 5AFUL 5E79O 4UB8O 2KXPA 1Q9GA 3WI5A 4F4BA 2ES9A 2GMYA 3PQUA 4FZLA 2F1TA 2XMXA 2Y7SA 3V8UA 2R4OA 5IYUA 3QRAA 4D64A 5FVNA 4GF4A 4D5UA 3AA6A 2F1CX 1THQA 2R4NA 3NJTA 3WI4A 3C5OA 4E1TA 3LK2B 1BT9A 4C4VA 8PRNA 3POXA 1ZHXA 3AA1A 2IWVA 2R8AA 2N2MA 3G7GA 3K19A 3LK42 3PF1A 4FESA 1ORMA 1T16A 2W81C 4K3BA 2XTRA 4N74A 2XE1A 1OPFA 1PHOA 1QJ9A 4UB6O 3SZDA 2IWWA 3AAAA 1OSMA 2PFXA 4G75A 5G38A 3T24A 4AUIA 5GTHO 5TISO 3BS0A 2O4DA 3FYXA 2CWQA 3NSGA 3PGSA 4N59A 4RL9A 5DL8A 5D5DA 3HW9A 1G90A 4AKRA 3O0EA 5G26A 3POUA 4IL6O 1GFOA 6PRNA 3AA7B 1GFQA 3LK3B 7PRNA 1E54A 4PJ0O 1MM5A 3A0BO 2OMFA 2QEUA 4O4XA 5B5EO 2KXPB 4O49A 5DIKA 3SYBA 3SZVA 4AKMA 4AYMC 1GFPA 1HXTA 2W80C 4AYID 3VZWX 5GV0A 4LSHA 2IJCA 2XE2A 5G39A 1Q9FA 3HOEA 3LK2A 2R89A 1ZHTA 5ADXL 3PORA 2X27X 3T0SA 5JDPA 2J1NA 2PRRA 2K0LA 2ERVA 2WVPA 4B61A 4AFKA 2AXTO 2MHLA 2R4LA 2XG6A 3AAAB 4FUVA 4O3XB 1GU9A 3DWNA 1BXWA 3BRYA 4O4UA 4N75A 2F1VA 4Z3TA 2OYOA 5AFUK 2GE4A 2N2LA 3BRZA 2K4TA 2J4UP 4RLCA 1YS5A 3JTYA 4JFBA 4AYDC 3AAEA 2WJQA 3HWBA 2PRNA 3LK41 5DIPA 4FSOA 1P8CA 4LSFA 3AA0A 1MM4A 4O3WA 3AA7A 2M06A 4G9QA 1IZNB 4JCHA 4LSIA 1VKEA 3BEYA 1H6S1 2WJRA 1QJPA 2O4VA 5DL6A 3A0HO 3SY7A 3SYSA 3VE2A 3VZUX 2KDYA 3PGUA 3UU2A 3DA4A 4XNLA 2XE3A 4O3ZA 4GHBA 2KZ7B 3C1LA 3SY9A
chains in the Genus database with same CATH topology
5DL7A 1ZHZA 3VY9X 4RLBA 3POQA 2Y0LA 4KRAA 4QQ1A 2Y0HA 1KNCA 2LHFA 2XTQA 4GCQA 2FGQX 2OUWA 2FGRA 3UAQA 3A2SX 4AYNA 4FSPA 2Q0TA 1MPFA 1PRNA 2YNKA 4FOZA 4AYEC 3RBHA 3AAEB 1ZHWA 3EMNX 5EE2A 3DA3A 3TZGA 4C69X 4E1SA 3T20A 2M07A 4FRTA 3AA0B 2LFUA 4LSEA 4RJXA 4BUMX 1HXUA 1ME5A 1IZNA 3PRNA 4FZNA 3UPGA 1BH3A 2Y2XA 3LVYA 2MNHA 4AZLA 4FZMA 5ADXK 1GFNA 1LW1A 1QJ8A 2XE5A 2AF7A 2YPVA 3AA6B 2KZ7A 4G76A 2KC0A 2Y0KA 3AA1B 3HOLA 2JN8A 4N58A 5DL5A 2ODJA 2QTKA 3PQSA 3KVDD 4KR4A 4XNKA 1P4TA 4RJWA 4U9CA 4O3YA 2PORA 3QRCA 1GFMA 5T5FA 4FMSA 4GCPA 4FRXA 2ZFGA 4FT6A 5PRNA 4GCSA 2JMMA 3VE1A 4AKRB 1HXXA 1ZHYA 3D7IA 2ZLDA 3VY8X 4D65A 3LK3A 3GP6A 4KR8A 5AFUL 2KXPA 1Q9GA 3WI5A 4F4BA 2ES9A 2GMYA 3PQUA 4FZLA 2F1TA 2XMXA 2Y7SA 3V8UA 5IYUA 3QRAA 4D64A 5FVNA 4GF4A 4D5UA 3AA6A 1THQA 3WI4A 3C5OA 4E1TA 3LK2B 1BT9A 8PRNA 3POXA 1ZHXA 3AA1A 3K19A 3G7GA 2N2MA 3LK42 4FESA 3VZTX 4PUXA 5DL6A 1ORMA 2W81C 5ADXL 2J4UP 2XTRA 2XE1A 1OPFA 1PHOA 1QJ9A 3SZDA 3AAAA 1OSMA 2PFXA 4G75A 3T24A 4AUIA 2O4DA 3FYXA 2CWQA 3NSGA 4N59A 4RL9A 5DL8A 5D5DA 3HW9A 1G90A 4AKRA 3O0EA 5G26A 3POUA 6PRNA 1GFOA 7PRNA 3AA7B 1GFQA 3LK3B 1E54A 1MM5A 2OMFA 2QEUA 4O4XA 2KXPB 4O49A 5DIKA 3SYBA 3SZVA 4AKMA 4AYMC 1GFPA 1HXTA 2W80C 4AYID 3VZWX 5GV0A 4LSHA 2IJCA 2XE2A 1Q9FA 3HOEA 3LK2A 1ZHTA 3PORA 2X27X 3T0SA 5JDPA 2J1NA 2PRRA 2K0LA 2ERVA 4B61A 4AFKA 2MHLA 2XG6A 4FUVA 3AAAB 4O3XB 1GU9A 4O4UA 1BXWA 2F1VA 4Z3TA 2OYOA 5AFUK 2GE4A 2N2LA 2K4TA 4RLCA 1YS5A 3JTYA 4JFBA 4AYDC 3AAEA 3HWBA 2PRNA 3LK41 5DIPA 4FSOA 1P8CA 4LSFA 3AA0A 1MM4A 4O3WA 3AA7A 2M06A 4G9QA 1IZNB 4JCHA 4LSIA 1VKEA 3BEYA 1H6S1 1QJPA 2O4VA 3SYSA 3VZUX 3SY7A 3VE2A 2KDYA 3UU2A 3DA4A 4XNLA 2XE3A 4O3ZA 4GHBA 2KZ7B 3C1LA 3SY9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LK2 A;  2KZ7 A;  3LK2 B;  3AA1 A;  3AA1 B;  3LK4 2;  5ADX L;  3AAA A;  3AAA B;  5AFU K;  3AAE A;  3AAE B;  3LK4 1;  4AKR A;  4AKR B;  3AA0 A;  3AA0 B;  3AA7 A;  3AA7 B;  3LK3 A;  1IZN A;  1IZN B;  3LK3 B;  5AFU L;  2KXP B;  2KXP A;  5ADX K;  3AA6 A;  3AA6 B;  2KZ7 B; 
#chains in the Genus database with same CATH topology
 5DL7 A;  1ZHZ A;  3VY9 X;  4CTD A;  4RLB A;  3POQ A;  2Y0L A;  4KRA A;  2R88 A;  4QQ1 A;  2Y0H A;  4FQE A;  1KNC A;  2LHF A;  2XTQ A;  4GCQ A;  2FGQ X;  2OUW A;  2FGR A;  3UAQ A;  2JQY A;  4C00 A;  3A2S X;  4AYN A;  4FSP A;  2Q0T A;  1MPF A;  1PRN A;  2YNK A;  4FOZ A;  4AYE C;  5B66 O;  3RBH A;  3AAE B;  1ZHW A;  3EMN X;  1T1L A;  3DA3 A;  5EE2 A;  3TZG A;  4C69 X;  4E1S A;  2R4P A;  3T20 A;  2M07 A;  4FRT A;  3AA0 B;  2LFU A;  4LSE A;  4RJX A;  5GTI O;  4BUM X;  1HXU A;  1ME5 A;  1IZN A;  3PRN A;  4FZN A;  3UPG A;  1BH3 A;  2Y2X A;  3LVY A;  2MNH A;  4AZL A;  4FZM A;  5ADX K;  1GFN A;  1LW1 A;  1QJ8 A;  2XE5 A;  2AF7 A;  1S5L O;  2YPV A;  3AA6 B;  4PR7 A;  5H2F O;  2KZ7 A;  4G76 A;  2KC0 A;  2X9K A;  3JCU O;  2Y0K A;  4C4V B;  3AA1 B;  3HOL A;  2JN8 A;  5KAI O;  4N58 A;  3KZI O;  5DL5 A;  2ODJ A;  2QTK A;  3DWO X;  3WU2 O;  3PQS A;  3KVD D;  4KR4 A;  4K3C A;  1P4T A;  4RJW A;  4XNK A;  4U9C A;  3DZM A;  4O3Y A;  2POR A;  3QRC A;  1GFM A;  5T5F A;  4FMS A;  4GCP A;  4FRX A;  2ZFG A;  4FT6 A;  3VZT X;  5PRN A;  4PUX A;  4GCS A;  2JMM A;  3PGR A;  3VE1 A;  5G3A A;  1HXX A;  1ZHY A;  3D7I A;  2ZLD A;  3VY8 X;  4AKR B;  4D65 A;  3LK3 A;  3GP6 A;  4KR8 A;  5KAF O;  5AFU L;  5E79 O;  4UB8 O;  2KXP A;  1Q9G A;  3WI5 A;  4F4B A;  2ES9 A;  2GMY A;  3PQU A;  4FZL A;  2F1T A;  2XMX A;  2Y7S A;  3V8U A;  2R4O A;  5IYU A;  3QRA A;  4D64 A;  5FVN A;  4GF4 A;  4D5U A;  3AA6 A;  2F1C X;  1THQ A;  2R4N A;  3NJT A;  3WI4 A;  3C5O A;  4E1T A;  3LK2 B;  1BT9 A;  4C4V A;  8PRN A;  3POX A;  1ZHX A;  3AA1 A;  2IWV A;  2R8A A;  2N2M A;  3G7G A;  3K19 A;  3LK4 2;  3PF1 A;  4FES A;  1ORM A;  1T16 A;  2W81 C;  4K3B A;  2XTR A;  4N74 A;  2XE1 A;  1OPF A;  1PHO A;  1QJ9 A;  4UB6 O;  3SZD A;  2IWW A;  3AAA A;  1OSM A;  2PFX A;  4G75 A;  5G38 A;  3T24 A;  4AUI A;  5GTH O;  5TIS O;  3BS0 A;  2O4D A;  3FYX A;  2CWQ A;  3NSG A;  3PGS A;  4N59 A;  4RL9 A;  5DL8 A;  5D5D A;  3HW9 A;  1G90 A;  4AKR A;  3O0E A;  5G26 A;  3POU A;  4IL6 O;  1GFO A;  6PRN A;  3AA7 B;  1GFQ A;  3LK3 B;  7PRN A;  1E54 A;  4PJ0 O;  1MM5 A;  3A0B O;  2OMF A;  2QEU A;  4O4X A;  5B5E O;  2KXP B;  4O49 A;  5DIK A;  3SYB A;  3SZV A;  4AKM A;  4AYM C;  1GFP A;  1HXT A;  2W80 C;  4AYI D;  3VZW X;  5GV0 A;  4LSH A;  2IJC A;  2XE2 A;  5G39 A;  1Q9F A;  3HOE A;  3LK2 A;  2R89 A;  1ZHT A;  5ADX L;  3POR A;  2X27 X;  3T0S A;  5JDP A;  2J1N A;  2PRR A;  2K0L A;  2ERV A;  2WVP A;  4B61 A;  4AFK A;  2AXT O;  2MHL A;  2R4L A;  2XG6 A;  3AAA B;  4FUV A;  4O3X B;  1GU9 A;  3DWN A;  1BXW A;  3BRY A;  4O4U A;  4N75 A;  2F1V A;  4Z3T A;  2OYO A;  5AFU K;  2GE4 A;  2N2L A;  3BRZ A;  2K4T A;  2J4U P;  4RLC A;  1YS5 A;  3JTY A;  4JFB A;  4AYD C;  3AAE A;  2WJQ A;  3HWB A;  2PRN A;  3LK4 1;  5DIP A;  4FSO A;  1P8C A;  4LSF A;  3AA0 A;  1MM4 A;  4O3W A;  3AA7 A;  2M06 A;  4G9Q A;  1IZN B;  4JCH A;  4LSI A;  1VKE A;  3BEY A;  1H6S 1;  2WJR A;  1QJP A;  2O4V A;  5DL6 A;  3A0H O;  3SY7 A;  3SYS A;  3VE2 A;  3VZU X;  2KDY A;  3PGU A;  3UU2 A;  3DA4 A;  4XNL A;  2XE3 A;  4O3Z A;  4GHB A;  2KZ7 B;  3C1L A;  3SY9 A; 
#chains in the Genus database with same CATH homology
 5DL7 A;  1ZHZ A;  3VY9 X;  4RLB A;  3POQ A;  2Y0L A;  4KRA A;  4QQ1 A;  2Y0H A;  1KNC A;  2LHF A;  2XTQ A;  4GCQ A;  2FGQ X;  2OUW A;  2FGR A;  3UAQ A;  3A2S X;  4AYN A;  4FSP A;  2Q0T A;  1MPF A;  1PRN A;  2YNK A;  4FOZ A;  4AYE C;  3RBH A;  3AAE B;  1ZHW A;  3EMN X;  5EE2 A;  3DA3 A;  3TZG A;  4C69 X;  4E1S A;  3T20 A;  2M07 A;  4FRT A;  3AA0 B;  2LFU A;  4LSE A;  4RJX A;  4BUM X;  1HXU A;  1ME5 A;  1IZN A;  3PRN A;  4FZN A;  3UPG A;  1BH3 A;  2Y2X A;  3LVY A;  2MNH A;  4AZL A;  4FZM A;  5ADX K;  1GFN A;  1LW1 A;  1QJ8 A;  2XE5 A;  2AF7 A;  2YPV A;  3AA6 B;  2KZ7 A;  4G76 A;  2KC0 A;  2Y0K A;  3AA1 B;  3HOL A;  2JN8 A;  4N58 A;  5DL5 A;  2ODJ A;  2QTK A;  3PQS A;  3KVD D;  4KR4 A;  4XNK A;  1P4T A;  4RJW A;  4U9C A;  4O3Y A;  2POR A;  3QRC A;  1GFM A;  5T5F A;  4FMS A;  4GCP A;  4FRX A;  2ZFG A;  4FT6 A;  5PRN A;  4GCS A;  2JMM A;  3VE1 A;  4AKR B;  1HXX A;  1ZHY A;  3D7I A;  2ZLD A;  3VY8 X;  4D65 A;  3LK3 A;  3GP6 A;  4KR8 A;  5AFU L;  2KXP A;  1Q9G A;  3WI5 A;  4F4B A;  2ES9 A;  2GMY A;  3PQU A;  4FZL A;  2F1T A;  2XMX A;  2Y7S A;  3V8U A;  5IYU A;  3QRA A;  4D64 A;  5FVN A;  4GF4 A;  4D5U A;  3AA6 A;  1THQ A;  3WI4 A;  3C5O A;  4E1T A;  3LK2 B;  1BT9 A;  8PRN A;  3POX A;  1ZHX A;  3AA1 A;  3K19 A;  3G7G A;  2N2M A;  3LK4 2;  4FES A;  3VZT X;  4PUX A;  5DL6 A;  1ORM A;  2W81 C;  5ADX L;  2J4U P;  2XTR A;  2XE1 A;  1OPF A;  1PHO A;  1QJ9 A;  3SZD A;  3AAA A;  1OSM A;  2PFX A;  4G75 A;  3T24 A;  4AUI A;  2O4D A;  3FYX A;  2CWQ A;  3NSG A;  4N59 A;  4RL9 A;  5DL8 A;  5D5D A;  3HW9 A;  1G90 A;  4AKR A;  3O0E A;  5G26 A;  3POU A;  6PRN A;  1GFO A;  7PRN A;  3AA7 B;  1GFQ A;  3LK3 B;  1E54 A;  1MM5 A;  2OMF A;  2QEU A;  4O4X A;  2KXP B;  4O49 A;  5DIK A;  3SYB A;  3SZV A;  4AKM A;  4AYM C;  1GFP A;  1HXT A;  2W80 C;  4AYI D;  3VZW X;  5GV0 A;  4LSH A;  2IJC A;  2XE2 A;  1Q9F A;  3HOE A;  3LK2 A;  1ZHT A;  3POR A;  2X27 X;  3T0S A;  5JDP A;  2J1N A;  2PRR A;  2K0L A;  2ERV A;  4B61 A;  4AFK A;  2MHL A;  2XG6 A;  4FUV A;  3AAA B;  4O3X B;  1GU9 A;  4O4U A;  1BXW A;  2F1V A;  4Z3T A;  2OYO A;  5AFU K;  2GE4 A;  2N2L A;  2K4T A;  4RLC A;  1YS5 A;  3JTY A;  4JFB A;  4AYD C;  3AAE A;  3HWB A;  2PRN A;  3LK4 1;  5DIP A;  4FSO A;  1P8C A;  4LSF A;  3AA0 A;  1MM4 A;  4O3W A;  3AA7 A;  2M06 A;  4G9Q A;  1IZN B;  4JCH A;  4LSI A;  1VKE A;  3BEY A;  1H6S 1;  1QJP A;  2O4V A;  3SYS A;  3VZU X;  3SY7 A;  3VE2 A;  2KDY A;  3UU2 A;  3DA4 A;  4XNL A;  2XE3 A;  4O3Z A;  4GHB A;  2KZ7 B;  3C1L A;  3SY9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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