3AAWA

Crystal structure of aspartate kinase from corynebacterium glutamicum in complex with lysine and threonine
Total Genus 129
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
129
sequence length
408
structure length
387
Chain Sequence
ALVVQKYGGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELLELAAAVNPVPPAREMDMLLTAGERISNALVAMAIESLGAEAQSFTVTPGRVREALDEGKICIVAGFVNKETRDVTTLGRGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRIVPNAQKLEKLSFEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYSNDPGTLIAGSMEDIPVEEAVLTGVATDKSEAKVTVLGISDKPGEAAKVFRALADAEINIDMVLQNVSSVEDGTTDITFTCPRSDGRRAMEILKKLQVQGNWTNVLYDDQVGKVSLVGAGMKSHPGVTAEFMEALRDVNVNIELISTSEIRISVLIREDDLDAAARALHEQFQLGG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Aspartokinase
publication title Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum
pubmed doi rcsb
source organism Corynebacterium glutamicum
molecule tags Transferase
total genus 129
structure length 387
sequence length 408
chains with identical sequence C
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2009-11-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
A PF13840 ACT_7 ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2130.10 Alpha Beta 2-Layer Sandwich VC0802-like VC0802-like 3aawA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3aawA01
2JI5A 3B8GA 2F06A 3ZZHA 4NDOA 4A7WA 2BRIA 2HMFA 3D2PA 4NDPA 3L76A 2BUFA 3AAWA 4JZ7A 2VA1A 3K4YA 1GS5A 3ZZGA 3LL5A 3U6UA 3WWNA 3QVHA 2J5VA 3K4OA 4A7XA 4F6TB 2WE4A 3AB2A 3L86A 3QUNA 2OGXB 4OLCA 1OHBA 3K52A 1ZVPA 2OGXA 2BTYA 3D41A 2BNEA 2AKOA 3QURA 2J4KA 1E19A 4KZTA 4USJA 3LKKA 3LL9A 3S6KA 3D2MA 2R98A 2V5HA 2JJ4A 4NDQB 2AP9A 2WXBA 3QVFA 4Q1TA 2J0WA 4F6TA 2IJ9A 4NDRB 4AB7A 1YBDA 3WWMA 2J0XA 2J4LA 3ZZIA 3KZFA 2RD5A 3S6GA 3C1NA 3D40A 3ZZFA 3K56A 3AB4A 1B7BA 1Z9DA 2R8VA 4NDQA 4JZ9A 4NDOB 4I49A 2JJXA 4AXSA 4NDPB 2WE5A 3NWYA 3C20A 3EK5A 2W21A 2BMUA 3C1MA 2BNDA 2J4JA 3T7BA 2E9YA 2BNFA 2J5TA 3TVIA 4NDRA 1GSJA 2X2WA 2CDQA 1ZHVA 2A1FA 3S6HA 4JZ8A 2V4YA 3QUOA 2BRXA 1OH9A 1OHAA 3EK6A
chains in the Genus database with same CATH superfamily
2JI5A 3B8GA 2F06A 3ZZHA 4NDOA 4A7WA 2BRIA 2HMFA 4KR9A 3D2PA 4NDPA 3L76A 2BUFA 3AAWA 4JZ7A 2VA1A 3K4YA 1GS5A 3ZZGA 3LL5A 3U6UA 3WWNA 3QVHA 2J5VA 3K4OA 4A7XA 4F6TB 2WE4A 3AB2A 3L86A 3QUNA 2OGXB 4OLCA 1OHBA 3K52A 1ZVPA 2OGXA 2BTYA 3D41A 2BNEA 2AKOA 3QURA 4KR7A 2J4KA 3V8VA 1E19A 4KZTA 4USJA 3LKKA 3LL9A 3S6KA 3D2MA 2R98A 2V5HA 2JJ4A 4NDQB 2AP9A 2WXBA 3LDGA 3QVFA 3TMAA 4Q1TA 2J0WA 4F6TA 2IJ9A 3TM5A 3LDUA 4NDRB 4AB7A 1YBDA 3WWMA 2J0XA 2J4LA 3ZZIA 3V97A 3KZFA 2RD5A 3S6GA 3C1NA 3D40A 3ZZFA 3K56A 3AB4A 1B7BA 1Z9DA 3K0BA 2R8VA 4NDQA 4JZ9A 4NDOB 4I49A 2JJXA 4AXSA 4KR6A 4NDPB 2WE5A 3NWYA 3C20A 3EK5A 2W21A 2BMUA 3C1MA 2BNDA 2J4JA 3T7BA 2E9YA 3TM4A 2BNFA 2J5TA 3TVIA 4NDRA 1GSJA 2X2WA 2C5SA 2CDQA 1ZHVA 2A1FA 3S6HA 4JZ8A 2V4YA 3QUOA 2BRXA 1OH9A 3TLJA 1OHAA 3EK6A
chains in the Genus database with same CATH topology
2JI5A 3B8GA 2F06A 3ZZHA 4NDOA 4A7WA 2BRIA 2HMFA 4KR9A 3D2PA 4NDPA 3L76A 2BUFA 3AAWA 4JZ7A 2VA1A 3K4YA 1GS5A 3ZZGA 3LL5A 3U6UA 3WWNA 3QVHA 2J5VA 3K4OA 4A7XA 4F6TB 2WE4A 3AB2A 3L86A 3QUNA 2OGXB 4OLCA 1OHBA 3K52A 1ZVPA 2OGXA 2BTYA 3D41A 2BNEA 2AKOA 3QURA 4KR7A 2J4KA 3V8VA 1E19A 4KZTA 4USJA 3LKKA 3LL9A 3S6KA 3D2MA 2R98A 2V5HA 2JJ4A 4NDQB 2AP9A 2WXBA 3LDGA 3QVFA 3TMAA 4Q1TA 2J0WA 4F6TA 2IJ9A 3TM5A 3LDUA 4NDRB 4AB7A 1YBDA 3WWMA 2J0XA 2J4LA 3ZZIA 3V97A 3KZFA 2RD5A 3S6GA 3C1NA 3D40A 3ZZFA 3K56A 3AB4A 1B7BA 1Z9DA 3K0BA 2R8VA 4NDQA 4JZ9A 4NDOB 4I49A 2JJXA 4AXSA 4KR6A 4NDPB 2WE5A 3NWYA 3C20A 3EK5A 2W21A 2BMUA 3C1MA 2BNDA 2J4JA 3T7BA 2E9YA 3TM4A 2BNFA 2J5TA 3TVIA 4NDRA 1GSJA 2X2WA 2C5SA 2CDQA 1ZHVA 2A1FA 3S6HA 4JZ8A 2V4YA 3QUOA 2BRXA 1OH9A 3TLJA 1OHAA 3EK6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JI5 A;  3B8G A;  2F06 A;  3ZZH A;  4NDO A;  4A7W A;  2BRI A;  2HMF A;  3D2P A;  4NDP A;  3L76 A;  2BUF A;  3AAW A;  4JZ7 A;  2VA1 A;  3K4Y A;  1GS5 A;  3ZZG A;  3LL5 A;  3U6U A;  3WWN A;  3QVH A;  2J5V A;  3K4O A;  4A7X A;  4F6T B;  2WE4 A;  3AB2 A;  3L86 A;  3QUN A;  2OGX B;  4OLC A;  1OHB A;  3K52 A;  1ZVP A;  2OGX A;  2BTY A;  3D41 A;  2BNE A;  2AKO A;  3QUR A;  2J4K A;  1E19 A;  4KZT A;  4USJ A;  3LKK A;  3LL9 A;  3S6K A;  3D2M A;  2R98 A;  2V5H A;  2JJ4 A;  4NDQ B;  2AP9 A;  2WXB A;  3QVF A;  4Q1T A;  2J0W A;  4F6T A;  2IJ9 A;  4NDR B;  4AB7 A;  1YBD A;  3WWM A;  2J0X A;  2J4L A;  3ZZI A;  3KZF A;  2RD5 A;  3S6G A;  3C1N A;  3D40 A;  3ZZF A;  3K56 A;  3AB4 A;  1B7B A;  1Z9D A;  2R8V A;  4NDQ A;  4JZ9 A;  4NDO B;  4I49 A;  2JJX A;  4AXS A;  4NDP B;  2WE5 A;  3NWY A;  3C20 A;  3EK5 A;  2W21 A;  2BMU A;  3C1M A;  2BND A;  2J4J A;  3T7B A;  2E9Y A;  2BNF A;  2J5T A;  3TVI A;  4NDR A;  1GSJ A;  2X2W A;  2CDQ A;  1ZHV A;  2A1F A;  3S6H A;  4JZ8 A;  2V4Y A;  3QUO A;  2BRX A;  1OH9 A;  1OHA A;  3EK6 A; 
#chains in the Genus database with same CATH topology
 2JI5 A;  3B8G A;  2F06 A;  3ZZH A;  4NDO A;  4A7W A;  2BRI A;  2HMF A;  4KR9 A;  3D2P A;  4NDP A;  3L76 A;  2BUF A;  3AAW A;  4JZ7 A;  2VA1 A;  3K4Y A;  1GS5 A;  3ZZG A;  3LL5 A;  3U6U A;  3WWN A;  3QVH A;  2J5V A;  3K4O A;  4A7X A;  4F6T B;  2WE4 A;  3AB2 A;  3L86 A;  3QUN A;  2OGX B;  4OLC A;  1OHB A;  3K52 A;  1ZVP A;  2OGX A;  2BTY A;  3D41 A;  2BNE A;  2AKO A;  3QUR A;  4KR7 A;  2J4K A;  3V8V A;  1E19 A;  4KZT A;  4USJ A;  3LKK A;  3LL9 A;  3S6K A;  3D2M A;  2R98 A;  2V5H A;  2JJ4 A;  4NDQ B;  2AP9 A;  2WXB A;  3LDG A;  3QVF A;  3TMA A;  4Q1T A;  2J0W A;  4F6T A;  2IJ9 A;  3TM5 A;  3LDU A;  4NDR B;  4AB7 A;  1YBD A;  3WWM A;  2J0X A;  2J4L A;  3ZZI A;  3V97 A;  3KZF A;  2RD5 A;  3S6G A;  3C1N A;  3D40 A;  3ZZF A;  3K56 A;  3AB4 A;  1B7B A;  1Z9D A;  3K0B A;  2R8V A;  4NDQ A;  4JZ9 A;  4NDO B;  4I49 A;  2JJX A;  4AXS A;  4KR6 A;  4NDP B;  2WE5 A;  3NWY A;  3C20 A;  3EK5 A;  2W21 A;  2BMU A;  3C1M A;  2BND A;  2J4J A;  3T7B A;  2E9Y A;  3TM4 A;  2BNF A;  2J5T A;  3TVI A;  4NDR A;  1GSJ A;  2X2W A;  2C5S A;  2CDQ A;  1ZHV A;  2A1F A;  3S6H A;  4JZ8 A;  2V4Y A;  3QUO A;  2BRX A;  1OH9 A;  3TLJ A;  1OHA A;  3EK6 A; 
#chains in the Genus database with same CATH homology
 2JI5 A;  3B8G A;  2F06 A;  3ZZH A;  4NDO A;  4A7W A;  2BRI A;  2HMF A;  4KR9 A;  3D2P A;  4NDP A;  3L76 A;  2BUF A;  3AAW A;  4JZ7 A;  2VA1 A;  3K4Y A;  1GS5 A;  3ZZG A;  3LL5 A;  3U6U A;  3WWN A;  3QVH A;  2J5V A;  3K4O A;  4A7X A;  4F6T B;  2WE4 A;  3AB2 A;  3L86 A;  3QUN A;  2OGX B;  4OLC A;  1OHB A;  3K52 A;  1ZVP A;  2OGX A;  2BTY A;  3D41 A;  2BNE A;  2AKO A;  3QUR A;  4KR7 A;  2J4K A;  3V8V A;  1E19 A;  4KZT A;  4USJ A;  3LKK A;  3LL9 A;  3S6K A;  3D2M A;  2R98 A;  2V5H A;  2JJ4 A;  4NDQ B;  2AP9 A;  2WXB A;  3LDG A;  3QVF A;  3TMA A;  4Q1T A;  2J0W A;  4F6T A;  2IJ9 A;  3TM5 A;  3LDU A;  4NDR B;  4AB7 A;  1YBD A;  3WWM A;  2J0X A;  2J4L A;  3ZZI A;  3V97 A;  3KZF A;  2RD5 A;  3S6G A;  3C1N A;  3D40 A;  3ZZF A;  3K56 A;  3AB4 A;  1B7B A;  1Z9D A;  3K0B A;  2R8V A;  4NDQ A;  4JZ9 A;  4NDO B;  4I49 A;  2JJX A;  4AXS A;  4KR6 A;  4NDP B;  2WE5 A;  3NWY A;  3C20 A;  3EK5 A;  2W21 A;  2BMU A;  3C1M A;  2BND A;  2J4J A;  3T7B A;  2E9Y A;  3TM4 A;  2BNF A;  2J5T A;  3TVI A;  4NDR A;  1GSJ A;  2X2W A;  2C5S A;  2CDQ A;  1ZHV A;  2A1F A;  3S6H A;  4JZ8 A;  2V4Y A;  3QUO A;  2BRX A;  1OH9 A;  3TLJ A;  1OHA A;  3EK6 A; 
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