3AAWA

Crystal structure of aspartate kinase from corynebacterium glutamicum in complex with lysine and threonine
Total Genus 129
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
129
sequence length
408
structure length
387
Chain Sequence
b'ALVVQKYGGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELLELAAAVNPVPPAREMDMLLTAGERISNALVAMAIESLGAEAQSFTVTPGRVREALDEGKICIVAGFVNKETRDVTTLGRGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRIVPNAQKLEKLSFEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYSNDPGTLIAGSMEDIPVEEAVLTGVATDKSEAKVTVLGISDKPGEAAKVFRALADAEINIDMVLQNVSSVEDGTTDITFTCPRSDGRRAMEILKKLQVQGNWTNVLYDDQVGKVSLVGAGMKSHPGVTAEFMEALRDVNVNIELISTSEIRISVLIREDDLDAAARALHEQFQLGG'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Aspartokinase
publication title Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum
pubmed doi rcsb
source organism Corynebacterium glutamicum
molecule tags Transferase
total genus 129
structure length 387
sequence length 408
chains with identical sequence C
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2009-11-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
A PF13840 ACT_7 ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2130.10 Alpha Beta 2-Layer Sandwich VC0802-like VC0802-like 3aawA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3aawA01
1B7BA 3AB4A 4NDPB 2BRXA 2J5TA 3K56A 4A7XA 3L86A 1ZHVA 3C1MA 2JJ4A 3QURA 4NDRB 3WWMA 3EK6A 2X2WA 3T7BA 3ZZFA 2RD5A 2R8VA 4AXSA 3K4YA 3D40A 3K52A 3C20A 2J0WA 2BUFA 2WE4A 1OHAA 1GSJA 4JZ8A 2V4YA 3K4OA 3WWNA 2BRIA 2JJXA 3LL9A 2BTYA 4NDOB 3NWYA 2J0XA 1GS5A 3TVIA 2J4KA 1OH9A 2BNFA 3QUOA 3KZFA 1OHBA 4F6TB 2CDQA 3AAWA 2VA1A 3S6KA 3D2PA 3U6UA 3D2MA 3QVFA 4I49A 4OLCA 1Z9DA 2AP9A 4NDPA 4NDQA 1YBDA 3C1NA 2OGXA 3S6HA 3LKKA 1ZVPA 4JZ9A 3ZZHA 2WE5A 3QVHA 4Q1TA 3D41A 2F06A 2J5VA 3ZZGA 2A1FA 2J4JA 4USJA 2R98A 2W21A 4NDOA 2JI5A 2BMUA 2IJ9A 3ZZIA 3AB2A 4NDQB 4F6TA 2AKOA 3L76A 4NDRA 2OGXB 3EK5A 4JZ7A 4AB7A 2E9YA 4KZTA 3QUNA 3LL5A 2BNEA 2J4LA 3B8GA 2BNDA 4A7WA 1E19A 3S6GA 2V5HA 2HMFA 2WXBA
chains in the Genus database with same CATH superfamily
1B7BA 3TMAA 3AB4A 4NDPB 2BRXA 2J5TA 4KR6A 3K56A 3K0BA 4A7XA 3L86A 1ZHVA 3C1MA 2JJ4A 3QURA 4NDRB 3WWMA 3EK6A 2X2WA 3T7BA 3ZZFA 2RD5A 2R8VA 4AXSA 3K4YA 3D40A 3K52A 3C20A 2J0WA 2BUFA 2WE4A 1OHAA 4KR7A 1GSJA 4JZ8A 2V4YA 3K4OA 3WWNA 2BRIA 2JJXA 3LL9A 2BTYA 4NDOB 3NWYA 2J0XA 1GS5A 3TVIA 2J4KA 1OH9A 2BNFA 3QUOA 3KZFA 1OHBA 4F6TB 2CDQA 3AAWA 2VA1A 3S6KA 3D2PA 3U6UA 3LDGA 3D2MA 3QVFA 4I49A 4OLCA 1Z9DA 2AP9A 4NDPA 4NDQA 3TM5A 1YBDA 3C1NA 2C5SA 2OGXA 3S6HA 3LKKA 1ZVPA 4JZ9A 3ZZHA 2WE5A 3QVHA 4Q1TA 3D41A 3TM4A 2F06A 2J5VA 4KR9A 3ZZGA 2A1FA 2J4JA 4USJA 3V8VA 2R98A 2W21A 4NDOA 2JI5A 2BMUA 2IJ9A 3LDUA 3ZZIA 3AB2A 4NDQB 4F6TA 2AKOA 3L76A 4NDRA 2OGXB 3EK5A 4JZ7A 4AB7A 2E9YA 4KZTA 3QUNA 3LL5A 2BNEA 2J4LA 3V97A 3B8GA 2BNDA 4A7WA 1E19A 3S6GA 3TLJA 2V5HA 2HMFA 2WXBA
chains in the Genus database with same CATH topology
1B7BA 3TMAA 3AB4A 4NDPB 2BRXA 2J5TA 4KR6A 3K56A 3K0BA 4A7XA 3L86A 1ZHVA 3C1MA 2JJ4A 3QURA 4NDRB 3WWMA 3EK6A 2X2WA 3T7BA 3ZZFA 2RD5A 2R8VA 4AXSA 3K4YA 3D40A 3K52A 3C20A 2J0WA 2BUFA 2WE4A 1OHAA 4KR7A 1GSJA 4JZ8A 2V4YA 3K4OA 3WWNA 2BRIA 2JJXA 3LL9A 2BTYA 4NDOB 3NWYA 2J0XA 1GS5A 3TVIA 2J4KA 1OH9A 2BNFA 3QUOA 3KZFA 1OHBA 4F6TB 2CDQA 3AAWA 2VA1A 3S6KA 3D2PA 3U6UA 3LDGA 3D2MA 3QVFA 4I49A 4OLCA 1Z9DA 2AP9A 4NDPA 4NDQA 3TM5A 1YBDA 3C1NA 2C5SA 2OGXA 3S6HA 3LKKA 1ZVPA 4JZ9A 3ZZHA 2WE5A 3QVHA 4Q1TA 3D41A 3TM4A 2F06A 2J5VA 4KR9A 3ZZGA 2A1FA 2J4JA 4USJA 3V8VA 2R98A 2W21A 4NDOA 2JI5A 2BMUA 2IJ9A 3LDUA 3ZZIA 3AB2A 4NDQB 4F6TA 2AKOA 3L76A 4NDRA 2OGXB 3EK5A 4JZ7A 4AB7A 2E9YA 4KZTA 3QUNA 3LL5A 2BNEA 2J4LA 3V97A 3B8GA 2BNDA 4A7WA 1E19A 3S6GA 3TLJA 2V5HA 2HMFA 2WXBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B7B A;  3AB4 A;  4NDP B;  2BRX A;  2J5T A;  3K56 A;  4A7X A;  3L86 A;  1ZHV A;  3C1M A;  2JJ4 A;  3QUR A;  4NDR B;  3WWM A;  3EK6 A;  2X2W A;  3T7B A;  3ZZF A;  2RD5 A;  2R8V A;  4AXS A;  3K4Y A;  3D40 A;  3K52 A;  3C20 A;  2J0W A;  2BUF A;  2WE4 A;  1OHA A;  1GSJ A;  4JZ8 A;  2V4Y A;  3K4O A;  3WWN A;  2BRI A;  2JJX A;  3LL9 A;  2BTY A;  4NDO B;  3NWY A;  2J0X A;  1GS5 A;  3TVI A;  2J4K A;  1OH9 A;  2BNF A;  3QUO A;  3KZF A;  1OHB A;  4F6T B;  2CDQ A;  3AAW A;  2VA1 A;  3S6K A;  3D2P A;  3U6U A;  3D2M A;  3QVF A;  4I49 A;  4OLC A;  1Z9D A;  2AP9 A;  4NDP A;  4NDQ A;  1YBD A;  3C1N A;  2OGX A;  3S6H A;  3LKK A;  1ZVP A;  4JZ9 A;  3ZZH A;  2WE5 A;  3QVH A;  4Q1T A;  3D41 A;  2F06 A;  2J5V A;  3ZZG A;  2A1F A;  2J4J A;  4USJ A;  2R98 A;  2W21 A;  4NDO A;  2JI5 A;  2BMU A;  2IJ9 A;  3ZZI A;  3AB2 A;  4NDQ B;  4F6T A;  2AKO A;  3L76 A;  4NDR A;  2OGX B;  3EK5 A;  4JZ7 A;  4AB7 A;  2E9Y A;  4KZT A;  3QUN A;  3LL5 A;  2BNE A;  2J4L A;  3B8G A;  2BND A;  4A7W A;  1E19 A;  3S6G A;  2V5H A;  2HMF A;  2WXB A; 
#chains in the Genus database with same CATH topology
 1B7B A;  3TMA A;  3AB4 A;  4NDP B;  2BRX A;  2J5T A;  4KR6 A;  3K56 A;  3K0B A;  4A7X A;  3L86 A;  1ZHV A;  3C1M A;  2JJ4 A;  3QUR A;  4NDR B;  3WWM A;  3EK6 A;  2X2W A;  3T7B A;  3ZZF A;  2RD5 A;  2R8V A;  4AXS A;  3K4Y A;  3D40 A;  3K52 A;  3C20 A;  2J0W A;  2BUF A;  2WE4 A;  1OHA A;  4KR7 A;  1GSJ A;  4JZ8 A;  2V4Y A;  3K4O A;  3WWN A;  2BRI A;  2JJX A;  3LL9 A;  2BTY A;  4NDO B;  3NWY A;  2J0X A;  1GS5 A;  3TVI A;  2J4K A;  1OH9 A;  2BNF A;  3QUO A;  3KZF A;  1OHB A;  4F6T B;  2CDQ A;  3AAW A;  2VA1 A;  3S6K A;  3D2P A;  3U6U A;  3LDG A;  3D2M A;  3QVF A;  4I49 A;  4OLC A;  1Z9D A;  2AP9 A;  4NDP A;  4NDQ A;  3TM5 A;  1YBD A;  3C1N A;  2C5S A;  2OGX A;  3S6H A;  3LKK A;  1ZVP A;  4JZ9 A;  3ZZH A;  2WE5 A;  3QVH A;  4Q1T A;  3D41 A;  3TM4 A;  2F06 A;  2J5V A;  4KR9 A;  3ZZG A;  2A1F A;  2J4J A;  4USJ A;  3V8V A;  2R98 A;  2W21 A;  4NDO A;  2JI5 A;  2BMU A;  2IJ9 A;  3LDU A;  3ZZI A;  3AB2 A;  4NDQ B;  4F6T A;  2AKO A;  3L76 A;  4NDR A;  2OGX B;  3EK5 A;  4JZ7 A;  4AB7 A;  2E9Y A;  4KZT A;  3QUN A;  3LL5 A;  2BNE A;  2J4L A;  3V97 A;  3B8G A;  2BND A;  4A7W A;  1E19 A;  3S6G A;  3TLJ A;  2V5H A;  2HMF A;  2WXB A; 
#chains in the Genus database with same CATH homology
 1B7B A;  3TMA A;  3AB4 A;  4NDP B;  2BRX A;  2J5T A;  4KR6 A;  3K56 A;  3K0B A;  4A7X A;  3L86 A;  1ZHV A;  3C1M A;  2JJ4 A;  3QUR A;  4NDR B;  3WWM A;  3EK6 A;  2X2W A;  3T7B A;  3ZZF A;  2RD5 A;  2R8V A;  4AXS A;  3K4Y A;  3D40 A;  3K52 A;  3C20 A;  2J0W A;  2BUF A;  2WE4 A;  1OHA A;  4KR7 A;  1GSJ A;  4JZ8 A;  2V4Y A;  3K4O A;  3WWN A;  2BRI A;  2JJX A;  3LL9 A;  2BTY A;  4NDO B;  3NWY A;  2J0X A;  1GS5 A;  3TVI A;  2J4K A;  1OH9 A;  2BNF A;  3QUO A;  3KZF A;  1OHB A;  4F6T B;  2CDQ A;  3AAW A;  2VA1 A;  3S6K A;  3D2P A;  3U6U A;  3LDG A;  3D2M A;  3QVF A;  4I49 A;  4OLC A;  1Z9D A;  2AP9 A;  4NDP A;  4NDQ A;  3TM5 A;  1YBD A;  3C1N A;  2C5S A;  2OGX A;  3S6H A;  3LKK A;  1ZVP A;  4JZ9 A;  3ZZH A;  2WE5 A;  3QVH A;  4Q1T A;  3D41 A;  3TM4 A;  2F06 A;  2J5V A;  4KR9 A;  3ZZG A;  2A1F A;  2J4J A;  4USJ A;  3V8V A;  2R98 A;  2W21 A;  4NDO A;  2JI5 A;  2BMU A;  2IJ9 A;  3LDU A;  3ZZI A;  3AB2 A;  4NDQ B;  4F6T A;  2AKO A;  3L76 A;  4NDR A;  2OGX B;  3EK5 A;  4JZ7 A;  4AB7 A;  2E9Y A;  4KZT A;  3QUN A;  3LL5 A;  2BNE A;  2J4L A;  3V97 A;  3B8G A;  2BND A;  4A7W A;  1E19 A;  3S6G A;  3TLJ A;  2V5H A;  2HMF A;  2WXB A; 
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