3AB4A

Crystal structure of feedback inhibition resistant mutant of aspartate kinase from corynebacterium glutamicum in complex with lysine and threonine
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
407
structure length
370
Chain Sequence
ALVVQKYGGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELLELAAAVNPVPPAREMDMLLTAGERISNALVAMAIESLGAEAQSFTGSVTPGRVREALDEGKICIVGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRIVPNAQKLEKLSFEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYSNDPGTLIAGSMEDIPVEEAVLTGVATDKSEAKVTVLGISDKPGEAAKVFRALADAEINIDMVLQNVFSDGTTDITFTCPRSDGRRAMEILKKLQVQGNWTNVLYDDQVGKVSLVGAGMKSHPGVTAEFMEALRDVNVNIELISTSEIRISVLIREDDLDAAARALHEQFQLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum
pubmed doi rcsb
source organism Corynebacterium glutamicum
molecule tags Transferase
molecule keywords Aspartokinase
total genus 113
structure length 370
sequence length 407
chains with identical sequence C, E, G, I, K, M, O
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2009-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
A PF13840 ACT_7 ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2130.10 Alpha Beta 2-Layer Sandwich VC0802-like VC0802-like 3ab4A02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3ab4A01
4F6TB 3B8GA 4Q1TA 3S6KA 1E19A 3ZZFA 2X2WA 1Z9DA 4NDOB 3QUNA 4NDQA 3ZZHA 2VA1A 3TVIA 2AKOA 3K52A 3C1MA 3L86A 1YBDA 2BMUA 1OHAA 3K56A 4NDRA 2JI5A 2WXBA 2E9YA 3LKKA 4JZ7A 2J4KA 4NDRB 3ZZIA 1ZHVA 3AAWA 3WWNA 2R8VA 4JZ9A 3L76A 2R98A 3C20A 3T7BA 1GS5A 4A7XA 1OHBA 3QVHA 4A7WA 3D40A 3C1NA 2JJXA 2HMFA 3K4OA 3ZZGA 2BUFA 3EK5A 1ZVPA 1OH9A 2BRXA 2J5TA 3NWYA 3D2PA 2BNDA 3D2MA 2AP9A 2WE4A 3QUOA 2RD5A 3WWMA 2V5HA 2J4JA 3QURA 3AB2A 3QVFA 2WE5A 2BRIA 4NDPA 2J0WA 2BNEA 4AB7A 2V4YA 4JZ8A 3EK6A 2J5VA 2BNFA 3S6HA 3U6UA 4F6TA 2BTYA 2JJ4A 2IJ9A 4NDPB 4OLCA 3AB4A 4KZTA 2OGXB 1B7BA 4USJA 3D41A 2J0XA 4NDOA 3LL9A 4I49A 3K4YA 4AXSA 2J4LA 3KZFA 4NDQB 2W21A 1GSJA 3S6GA 2F06A 2CDQA 2A1FA 3LL5A 2OGXA
chains in the Genus database with same CATH superfamily
4F6TB 3B8GA 4Q1TA 4KR9A 3S6KA 1E19A 3ZZFA 3V8VA 2X2WA 1Z9DA 4NDOB 3LDUA 3QUNA 4NDQA 3ZZHA 2VA1A 3TVIA 2AKOA 3K52A 3C1MA 4KR6A 3L86A 1YBDA 3TM4A 2BMUA 1OHAA 3K56A 4NDRA 2JI5A 2WXBA 2E9YA 3LDGA 3LKKA 4JZ7A 2J4KA 4NDRB 3ZZIA 1ZHVA 3AAWA 3K0BA 3WWNA 2R8VA 4JZ9A 3L76A 3V97A 2R98A 3C20A 3T7BA 1GS5A 4A7XA 1OHBA 3QVHA 4A7WA 3D40A 3C1NA 2JJXA 2HMFA 3K4OA 3ZZGA 2BUFA 3EK5A 1ZVPA 1OH9A 2BRXA 2C5SA 2J5TA 3NWYA 3D2PA 2BNDA 3D2MA 2AP9A 2WE4A 3QUOA 4KR7A 2RD5A 3WWMA 2V5HA 2J4JA 3QURA 3AB2A 3QVFA 2WE5A 3TLJA 2BRIA 4NDPA 2J0WA 2BNEA 4AB7A 3TMAA 2V4YA 4JZ8A 3EK6A 2J5VA 2BNFA 3S6HA 3U6UA 4F6TA 2BTYA 2JJ4A 2IJ9A 4NDPB 4OLCA 3AB4A 4KZTA 2OGXB 1B7BA 4USJA 3D41A 2J0XA 3TM5A 4NDOA 3LL9A 4I49A 3K4YA 4AXSA 2J4LA 3KZFA 4NDQB 2W21A 1GSJA 3S6GA 2F06A 2CDQA 2A1FA 3LL5A 2OGXA
chains in the Genus database with same CATH topology
4F6TB 3B8GA 4Q1TA 4KR9A 3S6KA 1E19A 3ZZFA 3V8VA 2X2WA 1Z9DA 4NDOB 3LDUA 3QUNA 4NDQA 3ZZHA 2VA1A 3TVIA 2AKOA 3K52A 3C1MA 4KR6A 3L86A 1YBDA 3TM4A 2BMUA 1OHAA 3K56A 4NDRA 2JI5A 2WXBA 2E9YA 3LDGA 3LKKA 4JZ7A 2J4KA 4NDRB 3ZZIA 1ZHVA 3AAWA 3K0BA 3WWNA 2R8VA 4JZ9A 3L76A 3V97A 2R98A 3C20A 3T7BA 1GS5A 4A7XA 1OHBA 3QVHA 4A7WA 3D40A 3C1NA 2JJXA 2HMFA 3K4OA 3ZZGA 2BUFA 3EK5A 1ZVPA 1OH9A 2BRXA 2C5SA 2J5TA 3NWYA 3D2PA 2BNDA 3D2MA 2AP9A 2WE4A 3QUOA 4KR7A 2RD5A 3WWMA 2V5HA 2J4JA 3QURA 3AB2A 3QVFA 2WE5A 3TLJA 2BRIA 4NDPA 2J0WA 2BNEA 4AB7A 3TMAA 2V4YA 4JZ8A 3EK6A 2J5VA 2BNFA 3S6HA 3U6UA 4F6TA 2BTYA 2JJ4A 2IJ9A 4NDPB 4OLCA 3AB4A 4KZTA 2OGXB 1B7BA 4USJA 3D41A 2J0XA 3TM5A 4NDOA 3LL9A 4I49A 3K4YA 4AXSA 2J4LA 3KZFA 4NDQB 2W21A 1GSJA 3S6GA 2F06A 2CDQA 2A1FA 3LL5A 2OGXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F6T B;  3B8G A;  4Q1T A;  3S6K A;  1E19 A;  3ZZF A;  2X2W A;  1Z9D A;  4NDO B;  3QUN A;  4NDQ A;  3ZZH A;  2VA1 A;  3TVI A;  2AKO A;  3K52 A;  3C1M A;  3L86 A;  1YBD A;  2BMU A;  1OHA A;  3K56 A;  4NDR A;  2JI5 A;  2WXB A;  2E9Y A;  3LKK A;  4JZ7 A;  2J4K A;  4NDR B;  3ZZI A;  1ZHV A;  3AAW A;  3WWN A;  2R8V A;  4JZ9 A;  3L76 A;  2R98 A;  3C20 A;  3T7B A;  1GS5 A;  4A7X A;  1OHB A;  3QVH A;  4A7W A;  3D40 A;  3C1N A;  2JJX A;  2HMF A;  3K4O A;  3ZZG A;  2BUF A;  3EK5 A;  1ZVP A;  1OH9 A;  2BRX A;  2J5T A;  3NWY A;  3D2P A;  2BND A;  3D2M A;  2AP9 A;  2WE4 A;  3QUO A;  2RD5 A;  3WWM A;  2V5H A;  2J4J A;  3QUR A;  3AB2 A;  3QVF A;  2WE5 A;  2BRI A;  4NDP A;  2J0W A;  2BNE A;  4AB7 A;  2V4Y A;  4JZ8 A;  3EK6 A;  2J5V A;  2BNF A;  3S6H A;  3U6U A;  4F6T A;  2BTY A;  2JJ4 A;  2IJ9 A;  4NDP B;  4OLC A;  3AB4 A;  4KZT A;  2OGX B;  1B7B A;  4USJ A;  3D41 A;  2J0X A;  4NDO A;  3LL9 A;  4I49 A;  3K4Y A;  4AXS A;  2J4L A;  3KZF A;  4NDQ B;  2W21 A;  1GSJ A;  3S6G A;  2F06 A;  2CDQ A;  2A1F A;  3LL5 A;  2OGX A; 
#chains in the Genus database with same CATH topology
 4F6T B;  3B8G A;  4Q1T A;  4KR9 A;  3S6K A;  1E19 A;  3ZZF A;  3V8V A;  2X2W A;  1Z9D A;  4NDO B;  3LDU A;  3QUN A;  4NDQ A;  3ZZH A;  2VA1 A;  3TVI A;  2AKO A;  3K52 A;  3C1M A;  4KR6 A;  3L86 A;  1YBD A;  3TM4 A;  2BMU A;  1OHA A;  3K56 A;  4NDR A;  2JI5 A;  2WXB A;  2E9Y A;  3LDG A;  3LKK A;  4JZ7 A;  2J4K A;  4NDR B;  3ZZI A;  1ZHV A;  3AAW A;  3K0B A;  3WWN A;  2R8V A;  4JZ9 A;  3L76 A;  3V97 A;  2R98 A;  3C20 A;  3T7B A;  1GS5 A;  4A7X A;  1OHB A;  3QVH A;  4A7W A;  3D40 A;  3C1N A;  2JJX A;  2HMF A;  3K4O A;  3ZZG A;  2BUF A;  3EK5 A;  1ZVP A;  1OH9 A;  2BRX A;  2C5S A;  2J5T A;  3NWY A;  3D2P A;  2BND A;  3D2M A;  2AP9 A;  2WE4 A;  3QUO A;  4KR7 A;  2RD5 A;  3WWM A;  2V5H A;  2J4J A;  3QUR A;  3AB2 A;  3QVF A;  2WE5 A;  3TLJ A;  2BRI A;  4NDP A;  2J0W A;  2BNE A;  4AB7 A;  3TMA A;  2V4Y A;  4JZ8 A;  3EK6 A;  2J5V A;  2BNF A;  3S6H A;  3U6U A;  4F6T A;  2BTY A;  2JJ4 A;  2IJ9 A;  4NDP B;  4OLC A;  3AB4 A;  4KZT A;  2OGX B;  1B7B A;  4USJ A;  3D41 A;  2J0X A;  3TM5 A;  4NDO A;  3LL9 A;  4I49 A;  3K4Y A;  4AXS A;  2J4L A;  3KZF A;  4NDQ B;  2W21 A;  1GSJ A;  3S6G A;  2F06 A;  2CDQ A;  2A1F A;  3LL5 A;  2OGX A; 
#chains in the Genus database with same CATH homology
 4F6T B;  3B8G A;  4Q1T A;  4KR9 A;  3S6K A;  1E19 A;  3ZZF A;  3V8V A;  2X2W A;  1Z9D A;  4NDO B;  3LDU A;  3QUN A;  4NDQ A;  3ZZH A;  2VA1 A;  3TVI A;  2AKO A;  3K52 A;  3C1M A;  4KR6 A;  3L86 A;  1YBD A;  3TM4 A;  2BMU A;  1OHA A;  3K56 A;  4NDR A;  2JI5 A;  2WXB A;  2E9Y A;  3LDG A;  3LKK A;  4JZ7 A;  2J4K A;  4NDR B;  3ZZI A;  1ZHV A;  3AAW A;  3K0B A;  3WWN A;  2R8V A;  4JZ9 A;  3L76 A;  3V97 A;  2R98 A;  3C20 A;  3T7B A;  1GS5 A;  4A7X A;  1OHB A;  3QVH A;  4A7W A;  3D40 A;  3C1N A;  2JJX A;  2HMF A;  3K4O A;  3ZZG A;  2BUF A;  3EK5 A;  1ZVP A;  1OH9 A;  2BRX A;  2C5S A;  2J5T A;  3NWY A;  3D2P A;  2BND A;  3D2M A;  2AP9 A;  2WE4 A;  3QUO A;  4KR7 A;  2RD5 A;  3WWM A;  2V5H A;  2J4J A;  3QUR A;  3AB2 A;  3QVF A;  2WE5 A;  3TLJ A;  2BRI A;  4NDP A;  2J0W A;  2BNE A;  4AB7 A;  3TMA A;  2V4Y A;  4JZ8 A;  3EK6 A;  2J5V A;  2BNF A;  3S6H A;  3U6U A;  4F6T A;  2BTY A;  2JJ4 A;  2IJ9 A;  4NDP B;  4OLC A;  3AB4 A;  4KZT A;  2OGX B;  1B7B A;  4USJ A;  3D41 A;  2J0X A;  3TM5 A;  4NDO A;  3LL9 A;  4I49 A;  3K4Y A;  4AXS A;  2J4L A;  3KZF A;  4NDQ B;  2W21 A;  1GSJ A;  3S6G A;  2F06 A;  2CDQ A;  2A1F A;  3LL5 A;  2OGX A; 
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