3AB4A

Crystal structure of feedback inhibition resistant mutant of aspartate kinase from corynebacterium glutamicum in complex with lysine and threonine
Total Genus 113
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
407
structure length
370
Chain Sequence
b'ALVVQKYGGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELLELAAAVNPVPPAREMDMLLTAGERISNALVAMAIESLGAEAQSFTGSVTPGRVREALDEGKICIVGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRIVPNAQKLEKLSFEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYSNDPGTLIAGSMEDIPVEEAVLTGVATDKSEAKVTVLGISDKPGEAAKVFRALADAEINIDMVLQNVFSDGTTDITFTCPRSDGRRAMEILKKLQVQGNWTNVLYDDQVGKVSLVGAGMKSHPGVTAEFMEALRDVNVNIELISTSEIRISVLIREDDLDAAARALHEQFQLG'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Aspartokinase
publication title Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum
pubmed doi rcsb
source organism Corynebacterium glutamicum
molecule tags Transferase
total genus 113
structure length 370
sequence length 407
chains with identical sequence C, E, G, I, K, M, O
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2009-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
A PF13840 ACT_7 ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2130.10 Alpha Beta 2-Layer Sandwich VC0802-like VC0802-like 3ab4A02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3ab4A01
1E19A 2R98A 3C20A 3D2MA 2BNDA 4Q1TA 1GS5A 3KZFA 4JZ8A 1OHBA 2V5HA 3ZZGA 3TVIA 3QUNA 1ZVPA 2RD5A 3AAWA 3NWYA 4F6TB 4A7WA 2J5TA 1GSJA 2HMFA 1OHAA 3B8GA 2BRIA 2R8VA 4NDQA 3LKKA 3K56A 3C1NA 2J0XA 4USJA 4NDRA 1Z9DA 2W21A 2J4KA 4NDOB 2J0WA 3C1MA 3U6UA 4OLCA 4AB7A 3AB2A 3QVHA 2V4YA 4KZTA 3LL9A 2OGXA 3D41A 3LL5A 3QURA 2IJ9A 2JJ4A 3L86A 2J4JA 4JZ7A 3QVFA 4AXSA 4I49A 3ZZFA 2BNEA 4NDRB 1YBDA 2BRXA 2VA1A 2BMUA 2WE4A 3T7BA 4NDPA 3D40A 2OGXB 2A1FA 1ZHVA 2BUFA 4A7XA 4NDQB 3EK5A 3D2PA 3AB4A 2AP9A 2J4LA 2J5VA 3K52A 3K4YA 2X2WA 3K4OA 3EK6A 2JJXA 3S6KA 3ZZIA 3WWNA 3S6GA 3QUOA 2E9YA 4JZ9A 3WWMA 4NDOA 3ZZHA 4F6TA 2CDQA 2F06A 3L76A 4NDPB 1OH9A 2WE5A 2AKOA 1B7BA 2JI5A 3S6HA 2WXBA 2BTYA 2BNFA
chains in the Genus database with same CATH superfamily
1E19A 2R98A 3C20A 4KR6A 3D2MA 2BNDA 4Q1TA 1GS5A 3KZFA 4JZ8A 1OHBA 2V5HA 3LDGA 3ZZGA 3TVIA 1ZVPA 2RD5A 3QUNA 3AAWA 3NWYA 4F6TB 4A7WA 2J5TA 1GSJA 2HMFA 1OHAA 3B8GA 2BRIA 4KR9A 2R8VA 4NDQA 3LKKA 3K56A 3C1NA 2C5SA 4KR7A 2J0XA 3V97A 4USJA 4NDRA 1Z9DA 2W21A 2J4KA 4NDOB 2J0WA 3C1MA 3TMAA 4OLCA 3U6UA 4AB7A 3AB2A 3QVHA 2V4YA 4KZTA 3LL9A 2OGXA 3D41A 3LL5A 3QURA 2IJ9A 2JJ4A 3L86A 2J4JA 4JZ7A 3QVFA 4AXSA 4I49A 3ZZFA 2BNEA 4NDRB 1YBDA 2BRXA 2VA1A 2BMUA 2WE4A 3T7BA 3TM4A 3D40A 4NDPA 3TM5A 3TLJA 2OGXB 2A1FA 1ZHVA 2BUFA 4A7XA 4NDQB 3LDUA 3EK5A 3D2PA 3AB4A 2AP9A 2J4LA 2J5VA 3K52A 3K4YA 2X2WA 3K4OA 3EK6A 2JJXA 3S6KA 3ZZIA 3WWNA 3S6GA 3QUOA 2E9YA 4JZ9A 3WWMA 4NDOA 3ZZHA 4F6TA 2CDQA 2F06A 3L76A 4NDPB 3K0BA 1OH9A 2WE5A 2AKOA 3V8VA 1B7BA 2JI5A 3S6HA 2WXBA 2BTYA 2BNFA
chains in the Genus database with same CATH topology
1E19A 2R98A 3C20A 4KR6A 3D2MA 2BNDA 4Q1TA 1GS5A 3KZFA 4JZ8A 1OHBA 2V5HA 3LDGA 3ZZGA 3TVIA 1ZVPA 2RD5A 3QUNA 3AAWA 3NWYA 4F6TB 4A7WA 2J5TA 1GSJA 2HMFA 1OHAA 3B8GA 2BRIA 4KR9A 2R8VA 4NDQA 3LKKA 3K56A 3C1NA 2C5SA 4KR7A 2J0XA 3V97A 4USJA 4NDRA 1Z9DA 2W21A 2J4KA 4NDOB 2J0WA 3C1MA 3TMAA 4OLCA 3U6UA 4AB7A 3AB2A 3QVHA 2V4YA 4KZTA 3LL9A 2OGXA 3D41A 3LL5A 3QURA 2IJ9A 2JJ4A 3L86A 2J4JA 4JZ7A 3QVFA 4AXSA 4I49A 3ZZFA 2BNEA 4NDRB 1YBDA 2BRXA 2VA1A 2BMUA 2WE4A 3T7BA 3TM4A 3D40A 4NDPA 3TM5A 3TLJA 2OGXB 2A1FA 1ZHVA 2BUFA 4A7XA 4NDQB 3LDUA 3EK5A 3D2PA 3AB4A 2AP9A 2J4LA 2J5VA 3K52A 3K4YA 2X2WA 3K4OA 3EK6A 2JJXA 3S6KA 3ZZIA 3WWNA 3S6GA 3QUOA 2E9YA 4JZ9A 3WWMA 4NDOA 3ZZHA 4F6TA 2CDQA 2F06A 3L76A 4NDPB 3K0BA 1OH9A 2WE5A 2AKOA 3V8VA 1B7BA 2JI5A 3S6HA 2WXBA 2BTYA 2BNFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E19 A;  2R98 A;  3C20 A;  3D2M A;  2BND A;  4Q1T A;  1GS5 A;  3KZF A;  4JZ8 A;  1OHB A;  2V5H A;  3ZZG A;  3TVI A;  3QUN A;  1ZVP A;  2RD5 A;  3AAW A;  3NWY A;  4F6T B;  4A7W A;  2J5T A;  1GSJ A;  2HMF A;  1OHA A;  3B8G A;  2BRI A;  2R8V A;  4NDQ A;  3LKK A;  3K56 A;  3C1N A;  2J0X A;  4USJ A;  4NDR A;  1Z9D A;  2W21 A;  2J4K A;  4NDO B;  2J0W A;  3C1M A;  3U6U A;  4OLC A;  4AB7 A;  3AB2 A;  3QVH A;  2V4Y A;  4KZT A;  3LL9 A;  2OGX A;  3D41 A;  3LL5 A;  3QUR A;  2IJ9 A;  2JJ4 A;  3L86 A;  2J4J A;  4JZ7 A;  3QVF A;  4AXS A;  4I49 A;  3ZZF A;  2BNE A;  4NDR B;  1YBD A;  2BRX A;  2VA1 A;  2BMU A;  2WE4 A;  3T7B A;  4NDP A;  3D40 A;  2OGX B;  2A1F A;  1ZHV A;  2BUF A;  4A7X A;  4NDQ B;  3EK5 A;  3D2P A;  3AB4 A;  2AP9 A;  2J4L A;  2J5V A;  3K52 A;  3K4Y A;  2X2W A;  3K4O A;  3EK6 A;  2JJX A;  3S6K A;  3ZZI A;  3WWN A;  3S6G A;  3QUO A;  2E9Y A;  4JZ9 A;  3WWM A;  4NDO A;  3ZZH A;  4F6T A;  2CDQ A;  2F06 A;  3L76 A;  4NDP B;  1OH9 A;  2WE5 A;  2AKO A;  1B7B A;  2JI5 A;  3S6H A;  2WXB A;  2BTY A;  2BNF A; 
#chains in the Genus database with same CATH topology
 1E19 A;  2R98 A;  3C20 A;  4KR6 A;  3D2M A;  2BND A;  4Q1T A;  1GS5 A;  3KZF A;  4JZ8 A;  1OHB A;  2V5H A;  3LDG A;  3ZZG A;  3TVI A;  1ZVP A;  2RD5 A;  3QUN A;  3AAW A;  3NWY A;  4F6T B;  4A7W A;  2J5T A;  1GSJ A;  2HMF A;  1OHA A;  3B8G A;  2BRI A;  4KR9 A;  2R8V A;  4NDQ A;  3LKK A;  3K56 A;  3C1N A;  2C5S A;  4KR7 A;  2J0X A;  3V97 A;  4USJ A;  4NDR A;  1Z9D A;  2W21 A;  2J4K A;  4NDO B;  2J0W A;  3C1M A;  3TMA A;  4OLC A;  3U6U A;  4AB7 A;  3AB2 A;  3QVH A;  2V4Y A;  4KZT A;  3LL9 A;  2OGX A;  3D41 A;  3LL5 A;  3QUR A;  2IJ9 A;  2JJ4 A;  3L86 A;  2J4J A;  4JZ7 A;  3QVF A;  4AXS A;  4I49 A;  3ZZF A;  2BNE A;  4NDR B;  1YBD A;  2BRX A;  2VA1 A;  2BMU A;  2WE4 A;  3T7B A;  3TM4 A;  3D40 A;  4NDP A;  3TM5 A;  3TLJ A;  2OGX B;  2A1F A;  1ZHV A;  2BUF A;  4A7X A;  4NDQ B;  3LDU A;  3EK5 A;  3D2P A;  3AB4 A;  2AP9 A;  2J4L A;  2J5V A;  3K52 A;  3K4Y A;  2X2W A;  3K4O A;  3EK6 A;  2JJX A;  3S6K A;  3ZZI A;  3WWN A;  3S6G A;  3QUO A;  2E9Y A;  4JZ9 A;  3WWM A;  4NDO A;  3ZZH A;  4F6T A;  2CDQ A;  2F06 A;  3L76 A;  4NDP B;  3K0B A;  1OH9 A;  2WE5 A;  2AKO A;  3V8V A;  1B7B A;  2JI5 A;  3S6H A;  2WXB A;  2BTY A;  2BNF A; 
#chains in the Genus database with same CATH homology
 1E19 A;  2R98 A;  3C20 A;  4KR6 A;  3D2M A;  2BND A;  4Q1T A;  1GS5 A;  3KZF A;  4JZ8 A;  1OHB A;  2V5H A;  3LDG A;  3ZZG A;  3TVI A;  1ZVP A;  2RD5 A;  3QUN A;  3AAW A;  3NWY A;  4F6T B;  4A7W A;  2J5T A;  1GSJ A;  2HMF A;  1OHA A;  3B8G A;  2BRI A;  4KR9 A;  2R8V A;  4NDQ A;  3LKK A;  3K56 A;  3C1N A;  2C5S A;  4KR7 A;  2J0X A;  3V97 A;  4USJ A;  4NDR A;  1Z9D A;  2W21 A;  2J4K A;  4NDO B;  2J0W A;  3C1M A;  3TMA A;  4OLC A;  3U6U A;  4AB7 A;  3AB2 A;  3QVH A;  2V4Y A;  4KZT A;  3LL9 A;  2OGX A;  3D41 A;  3LL5 A;  3QUR A;  2IJ9 A;  2JJ4 A;  3L86 A;  2J4J A;  4JZ7 A;  3QVF A;  4AXS A;  4I49 A;  3ZZF A;  2BNE A;  4NDR B;  1YBD A;  2BRX A;  2VA1 A;  2BMU A;  2WE4 A;  3T7B A;  3TM4 A;  3D40 A;  4NDP A;  3TM5 A;  3TLJ A;  2OGX B;  2A1F A;  1ZHV A;  2BUF A;  4A7X A;  4NDQ B;  3LDU A;  3EK5 A;  3D2P A;  3AB4 A;  2AP9 A;  2J4L A;  2J5V A;  3K52 A;  3K4Y A;  2X2W A;  3K4O A;  3EK6 A;  2JJX A;  3S6K A;  3ZZI A;  3WWN A;  3S6G A;  3QUO A;  2E9Y A;  4JZ9 A;  3WWM A;  4NDO A;  3ZZH A;  4F6T A;  2CDQ A;  2F06 A;  3L76 A;  4NDP B;  3K0B A;  1OH9 A;  2WE5 A;  2AKO A;  3V8V A;  1B7B A;  2JI5 A;  3S6H A;  2WXB A;  2BTY A;  2BNF A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...