3AB4A

Crystal structure of feedback inhibition resistant mutant of aspartate kinase from corynebacterium glutamicum in complex with lysine and threonine
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
407
structure length
370
Chain Sequence
ALVVQKYGGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELLELAAAVNPVPPAREMDMLLTAGERISNALVAMAIESLGAEAQSFTGSVTPGRVREALDEGKICIVGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRIVPNAQKLEKLSFEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYSNDPGTLIAGSMEDIPVEEAVLTGVATDKSEAKVTVLGISDKPGEAAKVFRALADAEINIDMVLQNVFSDGTTDITFTCPRSDGRRAMEILKKLQVQGNWTNVLYDDQVGKVSLVGAGMKSHPGVTAEFMEALRDVNVNIELISTSEIRISVLIREDDLDAAARALHEQFQLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum
pubmed doi rcsb
source organism Corynebacterium glutamicum
molecule tags Transferase
molecule keywords Aspartokinase
total genus 113
structure length 370
sequence length 407
chains with identical sequence C, E, G, I, K, M, O
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2009-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
A PF13840 ACT_7 ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2130.10 Alpha Beta 2-Layer Sandwich VC0802-like VC0802-like 3ab4A02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3ab4A01
2BUFA 2JJXA 2W21A 4F6TA 4AB7A 1ZVPA 1GSJA 2J4KA 4JZ7A 3QVFA 2BNFA 1YBDA 3C1NA 2BNEA 3C20A 3K4YA 2BRXA 2OGXB 2WE4A 2AP9A 3QVHA 4AXSA 2X2WA 4F6TB 3NWYA 4I49A 3S6HA 2F06A 1E19A 3EK6A 3L76A 2J4JA 3T7BA 4A7WA 4NDQB 3LL9A 4JZ8A 2RD5A 4NDRB 2V5HA 2WE5A 3D40A 4OLCA 2BNDA 2HMFA 4USJA 3WWMA 3AB2A 2JI5A 3C1MA 2J5VA 3KZFA 3S6GA 3TVIA 4KZTA 4NDPA 4NDOB 3AB4A 2IJ9A 2R8VA 3S6KA 3ZZGA 4NDQA 3EK5A 2BRIA 2CDQA 3AAWA 2J0XA 3LKKA 2JJ4A 2BTYA 3D2MA 4NDPB 1ZHVA 1B7BA 1GS5A 1OHBA 2V4YA 4NDRA 3QUNA 3ZZIA 3K52A 4JZ9A 2E9YA 2VA1A 3U6UA 2WXBA 2J5TA 3QUOA 3K4OA 4NDOA 2BMUA 2J4LA 3K56A 3ZZHA 2R98A 1OH9A 2AKOA 3D2PA 1OHAA 3B8GA 3D41A 4Q1TA 2OGXA 3QURA 4A7XA 2A1FA 3WWNA 1Z9DA 2J0WA 3LL5A 3ZZFA 3L86A
chains in the Genus database with same CATH superfamily
2BUFA 2JJXA 2W21A 4F6TA 4AB7A 1ZVPA 1GSJA 2J4KA 4JZ7A 3QVFA 3TM5A 2BNFA 1YBDA 3C1NA 2BNEA 3C20A 3K4YA 2BRXA 2OGXB 3LDGA 2WE4A 2AP9A 3QVHA 4AXSA 3V8VA 2X2WA 4F6TB 3TLJA 3NWYA 4I49A 3LDUA 3S6HA 2F06A 1E19A 3EK6A 3L76A 2J4JA 3T7BA 3K0BA 4A7WA 4NDQB 3LL9A 4JZ8A 2RD5A 4NDRB 2V5HA 2WE5A 3D40A 4OLCA 2BNDA 2HMFA 4USJA 4KR6A 3WWMA 3AB2A 2JI5A 3C1MA 2J5VA 3KZFA 4KR7A 3S6GA 3TVIA 4KZTA 4NDPA 4NDOB 3AB4A 2IJ9A 2R8VA 3S6KA 3ZZGA 3TM4A 4NDQA 3EK5A 2BRIA 2CDQA 3AAWA 2J0XA 3LKKA 2JJ4A 2BTYA 3D2MA 4NDPB 1ZHVA 1B7BA 1GS5A 1OHBA 3TMAA 2V4YA 4NDRA 3QUNA 3ZZIA 3K52A 2VA1A 2E9YA 4JZ9A 3U6UA 2WXBA 3V97A 2C5SA 2J5TA 3QUOA 3K4OA 4NDOA 2BMUA 2J4LA 4KR9A 3K56A 3ZZHA 2R98A 1OH9A 2AKOA 3D2PA 1OHAA 3B8GA 3D41A 4Q1TA 2OGXA 3QURA 4A7XA 2A1FA 3WWNA 1Z9DA 2J0WA 3LL5A 3ZZFA 3L86A
chains in the Genus database with same CATH topology
2BUFA 2JJXA 2W21A 4F6TA 4AB7A 1ZVPA 1GSJA 2J4KA 4JZ7A 3QVFA 3TM5A 2BNFA 1YBDA 3C1NA 2BNEA 3C20A 3K4YA 2BRXA 2OGXB 3LDGA 2WE4A 2AP9A 3QVHA 4AXSA 3V8VA 2X2WA 4F6TB 3TLJA 3NWYA 4I49A 3LDUA 3S6HA 2F06A 1E19A 3EK6A 3L76A 2J4JA 3T7BA 3K0BA 4A7WA 4NDQB 3LL9A 4JZ8A 2RD5A 4NDRB 2V5HA 2WE5A 3D40A 4OLCA 2BNDA 2HMFA 4USJA 4KR6A 3WWMA 3AB2A 2JI5A 3C1MA 2J5VA 3KZFA 4KR7A 3S6GA 3TVIA 4KZTA 4NDPA 4NDOB 3AB4A 2IJ9A 2R8VA 3S6KA 3ZZGA 3TM4A 4NDQA 3EK5A 2BRIA 2CDQA 3AAWA 2J0XA 3LKKA 2JJ4A 2BTYA 3D2MA 4NDPB 1ZHVA 1B7BA 1GS5A 1OHBA 3TMAA 2V4YA 4NDRA 3QUNA 3ZZIA 3K52A 2VA1A 2E9YA 4JZ9A 3U6UA 2WXBA 3V97A 2C5SA 2J5TA 3QUOA 3K4OA 4NDOA 2BMUA 2J4LA 4KR9A 3K56A 3ZZHA 2R98A 1OH9A 2AKOA 3D2PA 1OHAA 3B8GA 3D41A 4Q1TA 2OGXA 3QURA 4A7XA 2A1FA 3WWNA 1Z9DA 2J0WA 3LL5A 3ZZFA 3L86A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BUF A;  2JJX A;  2W21 A;  4F6T A;  4AB7 A;  1ZVP A;  1GSJ A;  2J4K A;  4JZ7 A;  3QVF A;  2BNF A;  1YBD A;  3C1N A;  2BNE A;  3C20 A;  3K4Y A;  2BRX A;  2OGX B;  2WE4 A;  2AP9 A;  3QVH A;  4AXS A;  2X2W A;  4F6T B;  3NWY A;  4I49 A;  3S6H A;  2F06 A;  1E19 A;  3EK6 A;  3L76 A;  2J4J A;  3T7B A;  4A7W A;  4NDQ B;  3LL9 A;  4JZ8 A;  2RD5 A;  4NDR B;  2V5H A;  2WE5 A;  3D40 A;  4OLC A;  2BND A;  2HMF A;  4USJ A;  3WWM A;  3AB2 A;  2JI5 A;  3C1M A;  2J5V A;  3KZF A;  3S6G A;  3TVI A;  4KZT A;  4NDP A;  4NDO B;  3AB4 A;  2IJ9 A;  2R8V A;  3S6K A;  3ZZG A;  4NDQ A;  3EK5 A;  2BRI A;  2CDQ A;  3AAW A;  2J0X A;  3LKK A;  2JJ4 A;  2BTY A;  3D2M A;  4NDP B;  1ZHV A;  1B7B A;  1GS5 A;  1OHB A;  2V4Y A;  4NDR A;  3QUN A;  3ZZI A;  3K52 A;  4JZ9 A;  2E9Y A;  2VA1 A;  3U6U A;  2WXB A;  2J5T A;  3QUO A;  3K4O A;  4NDO A;  2BMU A;  2J4L A;  3K56 A;  3ZZH A;  2R98 A;  1OH9 A;  2AKO A;  3D2P A;  1OHA A;  3B8G A;  3D41 A;  4Q1T A;  2OGX A;  3QUR A;  4A7X A;  2A1F A;  3WWN A;  1Z9D A;  2J0W A;  3LL5 A;  3ZZF A;  3L86 A; 
#chains in the Genus database with same CATH topology
 2BUF A;  2JJX A;  2W21 A;  4F6T A;  4AB7 A;  1ZVP A;  1GSJ A;  2J4K A;  4JZ7 A;  3QVF A;  3TM5 A;  2BNF A;  1YBD A;  3C1N A;  2BNE A;  3C20 A;  3K4Y A;  2BRX A;  2OGX B;  3LDG A;  2WE4 A;  2AP9 A;  3QVH A;  4AXS A;  3V8V A;  2X2W A;  4F6T B;  3TLJ A;  3NWY A;  4I49 A;  3LDU A;  3S6H A;  2F06 A;  1E19 A;  3EK6 A;  3L76 A;  2J4J A;  3T7B A;  3K0B A;  4A7W A;  4NDQ B;  3LL9 A;  4JZ8 A;  2RD5 A;  4NDR B;  2V5H A;  2WE5 A;  3D40 A;  4OLC A;  2BND A;  2HMF A;  4USJ A;  4KR6 A;  3WWM A;  3AB2 A;  2JI5 A;  3C1M A;  2J5V A;  3KZF A;  4KR7 A;  3S6G A;  3TVI A;  4KZT A;  4NDP A;  4NDO B;  3AB4 A;  2IJ9 A;  2R8V A;  3S6K A;  3ZZG A;  3TM4 A;  4NDQ A;  3EK5 A;  2BRI A;  2CDQ A;  3AAW A;  2J0X A;  3LKK A;  2JJ4 A;  2BTY A;  3D2M A;  4NDP B;  1ZHV A;  1B7B A;  1GS5 A;  1OHB A;  3TMA A;  2V4Y A;  4NDR A;  3QUN A;  3ZZI A;  3K52 A;  2VA1 A;  2E9Y A;  4JZ9 A;  3U6U A;  2WXB A;  3V97 A;  2C5S A;  2J5T A;  3QUO A;  3K4O A;  4NDO A;  2BMU A;  2J4L A;  4KR9 A;  3K56 A;  3ZZH A;  2R98 A;  1OH9 A;  2AKO A;  3D2P A;  1OHA A;  3B8G A;  3D41 A;  4Q1T A;  2OGX A;  3QUR A;  4A7X A;  2A1F A;  3WWN A;  1Z9D A;  2J0W A;  3LL5 A;  3ZZF A;  3L86 A; 
#chains in the Genus database with same CATH homology
 2BUF A;  2JJX A;  2W21 A;  4F6T A;  4AB7 A;  1ZVP A;  1GSJ A;  2J4K A;  4JZ7 A;  3QVF A;  3TM5 A;  2BNF A;  1YBD A;  3C1N A;  2BNE A;  3C20 A;  3K4Y A;  2BRX A;  2OGX B;  3LDG A;  2WE4 A;  2AP9 A;  3QVH A;  4AXS A;  3V8V A;  2X2W A;  4F6T B;  3TLJ A;  3NWY A;  4I49 A;  3LDU A;  3S6H A;  2F06 A;  1E19 A;  3EK6 A;  3L76 A;  2J4J A;  3T7B A;  3K0B A;  4A7W A;  4NDQ B;  3LL9 A;  4JZ8 A;  2RD5 A;  4NDR B;  2V5H A;  2WE5 A;  3D40 A;  4OLC A;  2BND A;  2HMF A;  4USJ A;  4KR6 A;  3WWM A;  3AB2 A;  2JI5 A;  3C1M A;  2J5V A;  3KZF A;  4KR7 A;  3S6G A;  3TVI A;  4KZT A;  4NDP A;  4NDO B;  3AB4 A;  2IJ9 A;  2R8V A;  3S6K A;  3ZZG A;  3TM4 A;  4NDQ A;  3EK5 A;  2BRI A;  2CDQ A;  3AAW A;  2J0X A;  3LKK A;  2JJ4 A;  2BTY A;  3D2M A;  4NDP B;  1ZHV A;  1B7B A;  1GS5 A;  1OHB A;  3TMA A;  2V4Y A;  4NDR A;  3QUN A;  3ZZI A;  3K52 A;  2VA1 A;  2E9Y A;  4JZ9 A;  3U6U A;  2WXB A;  3V97 A;  2C5S A;  2J5T A;  3QUO A;  3K4O A;  4NDO A;  2BMU A;  2J4L A;  4KR9 A;  3K56 A;  3ZZH A;  2R98 A;  1OH9 A;  2AKO A;  3D2P A;  1OHA A;  3B8G A;  3D41 A;  4Q1T A;  2OGX A;  3QUR A;  4A7X A;  2A1F A;  3WWN A;  1Z9D A;  2J0W A;  3LL5 A;  3ZZF A;  3L86 A; 
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