3AB4A

Crystal structure of feedback inhibition resistant mutant of aspartate kinase from corynebacterium glutamicum in complex with lysine and threonine
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
407
structure length
370
Chain Sequence
ALVVQKYGGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELLELAAAVNPVPPAREMDMLLTAGERISNALVAMAIESLGAEAQSFTGSVTPGRVREALDEGKICIVGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRIVPNAQKLEKLSFEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYSNDPGTLIAGSMEDIPVEEAVLTGVATDKSEAKVTVLGISDKPGEAAKVFRALADAEINIDMVLQNVFSDGTTDITFTCPRSDGRRAMEILKKLQVQGNWTNVLYDDQVGKVSLVGAGMKSHPGVTAEFMEALRDVNVNIELISTSEIRISVLIREDDLDAAARALHEQFQLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Aspartokinase
publication title Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum
pubmed doi rcsb
source organism Corynebacterium glutamicum
molecule tags Transferase
total genus 113
structure length 370
sequence length 407
chains with identical sequence C, E, G, I, K, M, O
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2009-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
A PF13840 ACT_7 ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2130.10 Alpha Beta 2-Layer Sandwich VC0802-like VC0802-like 3ab4A02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3ab4A01
4KZTA 2BRXA 4JZ8A 1B7BA 1YBDA 2JI5A 4F6TB 2WE5A 3L86A 4NDQA 3S6KA 4NDPB 3TVIA 3ZZGA 4AXSA 2BNDA 2HMFA 4AB7A 3S6GA 3QVFA 4NDOB 3NWYA 1E19A 3KZFA 3C20A 4A7XA 2BMUA 4OLCA 2V4YA 3D40A 2J4KA 2F06A 2BRIA 1ZVPA 3K56A 2BNFA 4JZ9A 2WXBA 4Q1TA 3LL9A 2OGXA 3K4OA 4A7WA 3U6UA 2IJ9A 1GS5A 3B8GA 4I49A 2VA1A 3ZZFA 2WE4A 4NDRB 4USJA 3AAWA 2AP9A 2J0XA 2RD5A 3D2PA 4NDQB 2BNEA 3K4YA 3QUNA 2BUFA 3QUOA 2J4JA 3C1NA 2W21A 1OH9A 3EK6A 4F6TA 1ZHVA 2J0WA 4NDPA 3D2MA 3ZZIA 4JZ7A 1OHBA 4NDRA 3C1MA 3D41A 2AKOA 3T7BA 2J5VA 2E9YA 4NDOA 3LL5A 1OHAA 3WWNA 2BTYA 3ZZHA 2R98A 3K52A 3WWMA 2OGXB 2CDQA 2X2WA 2J4LA 2JJXA 2J5TA 2R8VA 3QVHA 2A1FA 2V5HA 1GSJA 3L76A 3LKKA 3S6HA 3AB2A 3AB4A 1Z9DA 3QURA 2JJ4A 3EK5A
chains in the Genus database with same CATH superfamily
4KZTA 2BRXA 4JZ8A 1B7BA 1YBDA 2JI5A 4F6TB 2WE5A 3L86A 4NDQA 3K0BA 3S6KA 4NDPB 3TVIA 3ZZGA 4AXSA 2BNDA 2HMFA 3TLJA 4AB7A 4KR7A 3S6GA 3QVFA 4NDOB 3NWYA 3LDUA 3TM5A 1E19A 3KZFA 3C20A 4A7XA 2BMUA 4OLCA 2V4YA 3D40A 2J4KA 2F06A 2BRIA 1ZVPA 3K56A 2BNFA 4JZ9A 2WXBA 4Q1TA 3V8VA 3LL9A 2OGXA 4KR9A 3K4OA 4A7WA 3U6UA 2IJ9A 1GS5A 3B8GA 4I49A 2VA1A 3ZZFA 3TM4A 2WE4A 4NDRB 4USJA 3AAWA 2AP9A 2J0XA 3V97A 2RD5A 3LDGA 3D2PA 4NDQB 2BNEA 3K4YA 3QUNA 2BUFA 3QUOA 2J4JA 3C1NA 2W21A 1OH9A 3EK6A 4F6TA 1ZHVA 2J0WA 4NDPA 2C5SA 3D2MA 3ZZIA 4JZ7A 1OHBA 4NDRA 3C1MA 3D41A 2AKOA 3T7BA 2J5VA 2E9YA 4NDOA 3LL5A 1OHAA 3WWNA 2BTYA 3ZZHA 2R98A 3K52A 3WWMA 2OGXB 2CDQA 2X2WA 2J4LA 2JJXA 4KR6A 2J5TA 2R8VA 3QVHA 2A1FA 2V5HA 1GSJA 3L76A 3LKKA 3TMAA 3S6HA 3AB2A 3AB4A 1Z9DA 3QURA 2JJ4A 3EK5A
chains in the Genus database with same CATH topology
4KZTA 2BRXA 4JZ8A 1B7BA 1YBDA 2JI5A 4F6TB 2WE5A 3L86A 4NDQA 3K0BA 3S6KA 4NDPB 3TVIA 3ZZGA 4AXSA 2BNDA 2HMFA 3TLJA 4AB7A 4KR7A 3S6GA 3QVFA 4NDOB 3NWYA 3LDUA 3TM5A 1E19A 3KZFA 3C20A 4A7XA 2BMUA 4OLCA 2V4YA 3D40A 2J4KA 2F06A 2BRIA 1ZVPA 3K56A 2BNFA 4JZ9A 2WXBA 4Q1TA 3V8VA 3LL9A 2OGXA 4KR9A 3K4OA 4A7WA 3U6UA 2IJ9A 1GS5A 3B8GA 4I49A 2VA1A 3ZZFA 3TM4A 2WE4A 4NDRB 4USJA 3AAWA 2AP9A 2J0XA 3V97A 2RD5A 3LDGA 3D2PA 4NDQB 2BNEA 3K4YA 3QUNA 2BUFA 3QUOA 2J4JA 3C1NA 2W21A 1OH9A 3EK6A 4F6TA 1ZHVA 2J0WA 4NDPA 2C5SA 3D2MA 3ZZIA 4JZ7A 1OHBA 4NDRA 3C1MA 3D41A 2AKOA 3T7BA 2J5VA 2E9YA 4NDOA 3LL5A 1OHAA 3WWNA 2BTYA 3ZZHA 2R98A 3K52A 3WWMA 2OGXB 2CDQA 2X2WA 2J4LA 2JJXA 4KR6A 2J5TA 2R8VA 3QVHA 2A1FA 2V5HA 1GSJA 3L76A 3LKKA 3TMAA 3S6HA 3AB2A 3AB4A 1Z9DA 3QURA 2JJ4A 3EK5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KZT A;  2BRX A;  4JZ8 A;  1B7B A;  1YBD A;  2JI5 A;  4F6T B;  2WE5 A;  3L86 A;  4NDQ A;  3S6K A;  4NDP B;  3TVI A;  3ZZG A;  4AXS A;  2BND A;  2HMF A;  4AB7 A;  3S6G A;  3QVF A;  4NDO B;  3NWY A;  1E19 A;  3KZF A;  3C20 A;  4A7X A;  2BMU A;  4OLC A;  2V4Y A;  3D40 A;  2J4K A;  2F06 A;  2BRI A;  1ZVP A;  3K56 A;  2BNF A;  4JZ9 A;  2WXB A;  4Q1T A;  3LL9 A;  2OGX A;  3K4O A;  4A7W A;  3U6U A;  2IJ9 A;  1GS5 A;  3B8G A;  4I49 A;  2VA1 A;  3ZZF A;  2WE4 A;  4NDR B;  4USJ A;  3AAW A;  2AP9 A;  2J0X A;  2RD5 A;  3D2P A;  4NDQ B;  2BNE A;  3K4Y A;  3QUN A;  2BUF A;  3QUO A;  2J4J A;  3C1N A;  2W21 A;  1OH9 A;  3EK6 A;  4F6T A;  1ZHV A;  2J0W A;  4NDP A;  3D2M A;  3ZZI A;  4JZ7 A;  1OHB A;  4NDR A;  3C1M A;  3D41 A;  2AKO A;  3T7B A;  2J5V A;  2E9Y A;  4NDO A;  3LL5 A;  1OHA A;  3WWN A;  2BTY A;  3ZZH A;  2R98 A;  3K52 A;  3WWM A;  2OGX B;  2CDQ A;  2X2W A;  2J4L A;  2JJX A;  2J5T A;  2R8V A;  3QVH A;  2A1F A;  2V5H A;  1GSJ A;  3L76 A;  3LKK A;  3S6H A;  3AB2 A;  3AB4 A;  1Z9D A;  3QUR A;  2JJ4 A;  3EK5 A; 
#chains in the Genus database with same CATH topology
 4KZT A;  2BRX A;  4JZ8 A;  1B7B A;  1YBD A;  2JI5 A;  4F6T B;  2WE5 A;  3L86 A;  4NDQ A;  3K0B A;  3S6K A;  4NDP B;  3TVI A;  3ZZG A;  4AXS A;  2BND A;  2HMF A;  3TLJ A;  4AB7 A;  4KR7 A;  3S6G A;  3QVF A;  4NDO B;  3NWY A;  3LDU A;  3TM5 A;  1E19 A;  3KZF A;  3C20 A;  4A7X A;  2BMU A;  4OLC A;  2V4Y A;  3D40 A;  2J4K A;  2F06 A;  2BRI A;  1ZVP A;  3K56 A;  2BNF A;  4JZ9 A;  2WXB A;  4Q1T A;  3V8V A;  3LL9 A;  2OGX A;  4KR9 A;  3K4O A;  4A7W A;  3U6U A;  2IJ9 A;  1GS5 A;  3B8G A;  4I49 A;  2VA1 A;  3ZZF A;  3TM4 A;  2WE4 A;  4NDR B;  4USJ A;  3AAW A;  2AP9 A;  2J0X A;  3V97 A;  2RD5 A;  3LDG A;  3D2P A;  4NDQ B;  2BNE A;  3K4Y A;  3QUN A;  2BUF A;  3QUO A;  2J4J A;  3C1N A;  2W21 A;  1OH9 A;  3EK6 A;  4F6T A;  1ZHV A;  2J0W A;  4NDP A;  2C5S A;  3D2M A;  3ZZI A;  4JZ7 A;  1OHB A;  4NDR A;  3C1M A;  3D41 A;  2AKO A;  3T7B A;  2J5V A;  2E9Y A;  4NDO A;  3LL5 A;  1OHA A;  3WWN A;  2BTY A;  3ZZH A;  2R98 A;  3K52 A;  3WWM A;  2OGX B;  2CDQ A;  2X2W A;  2J4L A;  2JJX A;  4KR6 A;  2J5T A;  2R8V A;  3QVH A;  2A1F A;  2V5H A;  1GSJ A;  3L76 A;  3LKK A;  3TMA A;  3S6H A;  3AB2 A;  3AB4 A;  1Z9D A;  3QUR A;  2JJ4 A;  3EK5 A; 
#chains in the Genus database with same CATH homology
 4KZT A;  2BRX A;  4JZ8 A;  1B7B A;  1YBD A;  2JI5 A;  4F6T B;  2WE5 A;  3L86 A;  4NDQ A;  3K0B A;  3S6K A;  4NDP B;  3TVI A;  3ZZG A;  4AXS A;  2BND A;  2HMF A;  3TLJ A;  4AB7 A;  4KR7 A;  3S6G A;  3QVF A;  4NDO B;  3NWY A;  3LDU A;  3TM5 A;  1E19 A;  3KZF A;  3C20 A;  4A7X A;  2BMU A;  4OLC A;  2V4Y A;  3D40 A;  2J4K A;  2F06 A;  2BRI A;  1ZVP A;  3K56 A;  2BNF A;  4JZ9 A;  2WXB A;  4Q1T A;  3V8V A;  3LL9 A;  2OGX A;  4KR9 A;  3K4O A;  4A7W A;  3U6U A;  2IJ9 A;  1GS5 A;  3B8G A;  4I49 A;  2VA1 A;  3ZZF A;  3TM4 A;  2WE4 A;  4NDR B;  4USJ A;  3AAW A;  2AP9 A;  2J0X A;  3V97 A;  2RD5 A;  3LDG A;  3D2P A;  4NDQ B;  2BNE A;  3K4Y A;  3QUN A;  2BUF A;  3QUO A;  2J4J A;  3C1N A;  2W21 A;  1OH9 A;  3EK6 A;  4F6T A;  1ZHV A;  2J0W A;  4NDP A;  2C5S A;  3D2M A;  3ZZI A;  4JZ7 A;  1OHB A;  4NDR A;  3C1M A;  3D41 A;  2AKO A;  3T7B A;  2J5V A;  2E9Y A;  4NDO A;  3LL5 A;  1OHA A;  3WWN A;  2BTY A;  3ZZH A;  2R98 A;  3K52 A;  3WWM A;  2OGX B;  2CDQ A;  2X2W A;  2J4L A;  2JJX A;  4KR6 A;  2J5T A;  2R8V A;  3QVH A;  2A1F A;  2V5H A;  1GSJ A;  3L76 A;  3LKK A;  3TMA A;  3S6H A;  3AB2 A;  3AB4 A;  1Z9D A;  3QUR A;  2JJ4 A;  3EK5 A; 
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