3ABHA

Crystal structure of the efc/f-bar domain of human pacsin2/syndapin ii (2.0 a)
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
288
structure length
288
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQFEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II
pubmed doi rcsb
molecule tags Endocytosis
source organism Homo sapiens
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 114
structure length 288
sequence length 288
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3abhA01
4FZSA 1I4TA 2RAJA 1X04A 1ZWWA 2D1LA 3HAHA 1I4DA 3I2WA 5C5BB 3M3WA 1I49A 4ATMA 3QNIA 3SOGA 2FICA 2C08A 3PLTA 3G9GA 2RAIA 2Z0NA 2Z0VA 2V0OA 1X03A 2Z0OA 3CAZA 3HAJA 4NSWA 3ABHA 2D4CA 4WPCA 2EFLA 1I4LA 4H8SA 3DYTA 2EFKA 4AKVA 2X3VA 3HAIA 3SYVA 3QE6A 3ACOA 3QWEA 5C5BA 2X3XA 4I1QA 3OK8A 2YKTA 2Q13A 1Y2OA 4WPEA 4NQIA 4AVMA 1URUA 4DCNC 3Q84A 2RAKA 4DYLA 2Q12A 3LLLA 2ELBA 3Q0KA 2X3WA 1WDZA 4BNEA
chains in the Genus database with same CATH superfamily
1I4DA 1HXKA 4ATMA 3VKHA 1UPXA 4EZXA 3C7NA 2YIVX 2C08A 2QXLA 3EJRA 4IWOA 2OZNB 4EZRA 4PO2A 2EFLA 1TQSA 1TQUA 3Q84A 2PMRA 1O7DB 4IM0A 3I2WA 3CVRA 4IW0A 4AZ6A 1MJGA 1DKXA 3FD9A 4JWCA 4AZ5A 2OBMA 1SUFA 3I04A 3ACOA 1R5EA 2X3XA 3EJPA 2YI9A 3DX3A 3KAVA 1WDZA 3KAWA 2F7RA 4AZIA 2OBLA 4HR1A 2EWFA 3CZNA 2WYIA 3B53X 3OHXM 4JN4A 4UDYX 2F1AA 2WINM 2OO2A 4IWPA 4M0MA 4IM3A 3BLBA 4DYLA 2LM0A 2Q12A 1TQVA 2ELBA 1GNLA 1I4TA 2YL8A 1R34A 3DX4A 4EZWA 4NSWA 2MI7A 3EJUA 3QNJA 2N3KA 3RPMA 1DKYA 2RT6A 4EZOA 3EJTA 4DCNC 2F7OA 2RAKA 1OAOA 2OW7A 2KHOA 4E3CA 5KBPA 4R5IA 3DDGA 1SU7A 2EX3B 3D2EA 2WYHA 3ZEDA 4JWDA 3DX1A 4WPEA 1DKZA 4NPHA 4FZPA 4EZSA 4BNEA 4FZSA 2LXYA 4R5GA 3ERCC 2D1LA 5C5BB 1OA0A 4JWEA 1JQKA 2Z0NA 1ZYLA 4JLCA 3O3OB 4EZNA 3T46A 3VEAA 5FLEX 1Y2OA 3BUIA 3LMFA 1HTYA 2YL6A 3EJSA 4UDXX 2ND1A 1E1DA 2EFKA 3BUQA 3O3NB 3O3MB 3D2FA 2F7PA 3I39X 4H8SA 4IWQA 3HAHA 2OW6A 3DX2A 3BVWA 3T4AG 2YIAA 4H6IA 2Z0OA 3OWGA 3RV0A 1TQTA 1E2UA 2YIBA 2ALWA 2QFFA 5C5BA 4KIKB 4B9QA 2X3WA 4R5KA 3D50A 2RAIA 2Z0VA 1YWMA 2JNKA 4EZVA 3DX0A 1O7DC 3CZSA 1SU6A 3B52X 1URUA 3EJQA 1I49A 3RV1A 3L3OM 3D51A 5E84A 3T49A 4EZUA 3QWEA 2ND0A 3KDRA 1TQWA 4HY9A 3DDFA 3M3WA 4JNFA 4EZPA 2YLLA 3BVVA 4KIKA 3BUPA 3CAZA 3BUBA 3D4YA 2NCZA 2X5CA 3DYTA 3ER9B 2X3VA 3B51X 2JNSA 3UITA 4E81A 2GAFD 2Q13A 3BUDA 3Q0KA 4R5JA 4AZHA 2YLAA 2RAJA 1ZWWA 3DPOA 1HWWA 1R33A 4AZCB 2FICA 1QWNA 3D4ZA 3G9GA 2V0OA 3HAJA 2PY6A 2YI8A 4AZ7A 1W9MA 2YL5A 3BVUA 2GA9D 3QA8A 4JNEA 3SOGA 4F00A 3L3PA 1X03A 3T48A 3ABHA 5FIGA 2Z8YA 3F7WA 4FZOA 4D8JA 3DPQA 4EZZA 4EZTA 3T47A 4NQIA 4AVMA 3LLLA 3CV5A 2F18A 3VEBA 3LVTA 4G6QA 2ZXQA 4EZYA 3BVTA 4AZBA 3I01A 2D4CA 4AKVA 3HAIA 3SYVA 4I1QA 1PS3A 4AZCA 2YKTA 3A98A 1GN9A 4HYBA 1E9VA 2QKWA 4H6HA 1X04A 4JWIA 3ER8C 3QNIA 2F7QA 3PLTA 3BVXA 4F01A 1OA1A 1I4LA 1LQ7A 2FYVA 3OK8A 1QX1A 1QWUA 4FM3A 3GI7A 1GNTA 1SU8A 5TKYA 2F1BA 2O0I1 4EZQA 3CKDA 4IM2A 4WPCA 4AZGA 2GF4A 1U00A 3DPPA 4HR1B 3D52A 4R5LA 2YL9A 4JL9A 3QE6A
chains in the Genus database with same CATH topology
4FZSA 1I4TA 2RAJA 1X04A 1ZWWA 2D1LA 3HAHA 1I4DA 3I2WA 5C5BB 3M3WA 1I49A 4ATMA 3QNIA 3SOGA 2FICA 2C08A 3PLTA 3G9GA 2RAIA 2Z0NA 2Z0VA 2V0OA 1X03A 2Z0OA 3CAZA 3HAJA 4NSWA 3ABHA 2D4CA 4WPCA 2EFLA 1I4LA 4H8SA 3DYTA 2EFKA 4AKVA 2X3VA 3HAIA 3SYVA 3QE6A 3ACOA 3QWEA 5C5BA 2X3XA 4I1QA 3OK8A 2YKTA 2Q13A 1Y2OA 4WPEA 4NQIA 4AVMA 1URUA 4DCNC 3Q84A 2RAKA 4DYLA 2Q12A 3LLLA 2ELBA 3Q0KA 2X3WA 1WDZA 4BNEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FZS A;  1I4T A;  2RAJ A;  1X04 A;  1ZWW A;  2D1L A;  3HAH A;  1I4D A;  3I2W A;  5C5B B;  3M3W A;  1I49 A;  4ATM A;  3QNI A;  3SOG A;  2FIC A;  2C08 A;  3PLT A;  3G9G A;  2RAI A;  2Z0N A;  2Z0V A;  2V0O A;  1X03 A;  2Z0O A;  3CAZ A;  3HAJ A;  4NSW A;  3ABH A;  2D4C A;  4WPC A;  2EFL A;  1I4L A;  4H8S A;  3DYT A;  2EFK A;  4AKV A;  2X3V A;  3HAI A;  3SYV A;  3QE6 A;  3ACO A;  3QWE A;  5C5B A;  2X3X A;  4I1Q A;  3OK8 A;  2YKT A;  2Q13 A;  1Y2O A;  4WPE A;  4NQI A;  4AVM A;  1URU A;  4DCN C;  3Q84 A;  2RAK A;  4DYL A;  2Q12 A;  3LLL A;  2ELB A;  3Q0K A;  2X3W A;  1WDZ A;  4BNE A; 
#chains in the Genus database with same CATH topology
 1I4D A;  1HXK A;  4ATM A;  3VKH A;  1UPX A;  4EZX A;  3C7N A;  2YIV X;  2C08 A;  2QXL A;  3EJR A;  4IWO A;  2OZN B;  4EZR A;  4PO2 A;  2EFL A;  1TQS A;  1TQU A;  3Q84 A;  2PMR A;  1O7D B;  4IM0 A;  3I2W A;  3CVR A;  4IW0 A;  4AZ6 A;  1MJG A;  1DKX A;  3FD9 A;  4JWC A;  4AZ5 A;  2OBM A;  1SUF A;  3I04 A;  3ACO A;  1R5E A;  2X3X A;  3EJP A;  2YI9 A;  3DX3 A;  3KAV A;  1WDZ A;  3KAW A;  2F7R A;  4AZI A;  2OBL A;  4HR1 A;  2EWF A;  3CZN A;  2WYI A;  3B53 X;  3OHX M;  4JN4 A;  4UDY X;  2F1A A;  2WIN M;  2OO2 A;  4IWP A;  4M0M A;  4IM3 A;  3BLB A;  4DYL A;  2LM0 A;  2Q12 A;  1TQV A;  2ELB A;  1GNL A;  1I4T A;  2YL8 A;  1R34 A;  3DX4 A;  4EZW A;  4NSW A;  2MI7 A;  3EJU A;  3QNJ A;  2N3K A;  3RPM A;  1DKY A;  2RT6 A;  4EZO A;  3EJT A;  4DCN C;  2F7O A;  2RAK A;  1OAO A;  2OW7 A;  2KHO A;  4E3C A;  5KBP A;  4R5I A;  3DDG A;  1SU7 A;  2EX3 B;  3D2E A;  2WYH A;  3ZED A;  4JWD A;  3DX1 A;  4WPE A;  1DKZ A;  4NPH A;  4FZP A;  4EZS A;  4BNE A;  4FZS A;  2LXY A;  4R5G A;  3ERC C;  2D1L A;  5C5B B;  1OA0 A;  4JWE A;  1JQK A;  2Z0N A;  1ZYL A;  4JLC A;  3O3O B;  4EZN A;  3T46 A;  3VEA A;  5FLE X;  1Y2O A;  3BUI A;  3LMF A;  1HTY A;  2YL6 A;  3EJS A;  4UDX X;  2ND1 A;  1E1D A;  2EFK A;  3BUQ A;  3O3N B;  3O3M B;  3D2F A;  2F7P A;  3I39 X;  4H8S A;  4IWQ A;  3HAH A;  2OW6 A;  3DX2 A;  3BVW A;  3T4A G;  2YIA A;  4H6I A;  2Z0O A;  3OWG A;  3RV0 A;  1TQT A;  1E2U A;  2YIB A;  2ALW A;  2QFF A;  5C5B A;  4KIK B;  4B9Q A;  2X3W A;  4R5K A;  3D50 A;  2RAI A;  2Z0V A;  1YWM A;  2JNK A;  4EZV A;  3DX0 A;  1O7D C;  3CZS A;  1SU6 A;  3B52 X;  1URU A;  3EJQ A;  1I49 A;  3RV1 A;  3L3O M;  3D51 A;  5E84 A;  3T49 A;  4EZU A;  3QWE A;  2ND0 A;  3KDR A;  1TQW A;  4HY9 A;  3DDF A;  3M3W A;  4JNF A;  4EZP A;  2YLL A;  3BVV A;  4KIK A;  3BUP A;  3CAZ A;  3BUB A;  3D4Y A;  2NCZ A;  2X5C A;  3DYT A;  3ER9 B;  2X3V A;  3B51 X;  2JNS A;  3UIT A;  4E81 A;  2GAF D;  2Q13 A;  3BUD A;  3Q0K A;  4R5J A;  4AZH A;  2YLA A;  2RAJ A;  1ZWW A;  3DPO A;  1HWW A;  1R33 A;  4AZC B;  2FIC A;  1QWN A;  3D4Z A;  3G9G A;  2V0O A;  3HAJ A;  2PY6 A;  2YI8 A;  4AZ7 A;  1W9M A;  2YL5 A;  3BVU A;  2GA9 D;  3QA8 A;  4JNE A;  3SOG A;  4F00 A;  3L3P A;  1X03 A;  3T48 A;  3ABH A;  5FIG A;  2Z8Y A;  3F7W A;  4FZO A;  4D8J A;  3DPQ A;  4EZZ A;  4EZT A;  3T47 A;  4NQI A;  4AVM A;  3LLL A;  3CV5 A;  2F18 A;  3VEB A;  3LVT A;  4G6Q A;  2ZXQ A;  4EZY A;  3BVT A;  4AZB A;  3I01 A;  2D4C A;  4AKV A;  3HAI A;  3SYV A;  4I1Q A;  1PS3 A;  4AZC A;  2YKT A;  3A98 A;  1GN9 A;  4HYB A;  1E9V A;  2QKW A;  4H6H A;  1X04 A;  4JWI A;  3ER8 C;  3QNI A;  2F7Q A;  3PLT A;  3BVX A;  4F01 A;  1OA1 A;  1I4L A;  1LQ7 A;  2FYV A;  3OK8 A;  1QX1 A;  1QWU A;  4FM3 A;  3GI7 A;  1GNT A;  1SU8 A;  5TKY A;  2F1B A;  2O0I 1;  4EZQ A;  3CKD A;  4IM2 A;  4WPC A;  4AZG A;  2GF4 A;  1U00 A;  3DPP A;  4HR1 B;  3D52 A;  4R5L A;  2YL9 A;  4JL9 A;  3QE6 A; 
#chains in the Genus database with same CATH homology
 4FZS A;  1I4T A;  2RAJ A;  1X04 A;  1ZWW A;  2D1L A;  3HAH A;  1I4D A;  3I2W A;  5C5B B;  3M3W A;  1I49 A;  4ATM A;  3QNI A;  3SOG A;  2FIC A;  2C08 A;  3PLT A;  3G9G A;  2RAI A;  2Z0N A;  2Z0V A;  2V0O A;  1X03 A;  2Z0O A;  3CAZ A;  3HAJ A;  4NSW A;  3ABH A;  2D4C A;  4WPC A;  2EFL A;  1I4L A;  4H8S A;  3DYT A;  2EFK A;  4AKV A;  2X3V A;  3HAI A;  3SYV A;  3QE6 A;  3ACO A;  3QWE A;  5C5B A;  2X3X A;  4I1Q A;  3OK8 A;  2YKT A;  2Q13 A;  1Y2O A;  4WPE A;  4NQI A;  4AVM A;  1URU A;  4DCN C;  3Q84 A;  2RAK A;  4DYL A;  2Q12 A;  3LLL A;  2ELB A;  3Q0K A;  2X3W A;  1WDZ A;  4BNE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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