3ABHA

Crystal structure of the efc/f-bar domain of human pacsin2/syndapin ii (2.0 a)
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
288
structure length
288
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQFEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Protein kinase C and casein kinase substrate in neurons prot
publication title Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II
pubmed doi rcsb
source organism Homo sapiens
molecule tags Endocytosis
total genus 114
structure length 288
sequence length 288
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3abhA01
2Q13A 4H8SA 1X03A 2RAJA 1I49A 2Z0NA 2EFLA 2V0OA 2Z0VA 4AKVA 1I4TA 3Q84A 3CAZA 1Y2OA 2EFKA 2YKTA 2X3XA 2RAIA 4DYLA 4I1QA 5C5BA 1X04A 3SYVA 4BNEA 4WPCA 3QE6A 3QNIA 1I4DA 4AVMA 2FICA 3OK8A 1ZWWA 3DYTA 3HAHA 2D4CA 1WDZA 2D1LA 2Z0OA 3PLTA 2C08A 3I2WA 2ELBA 3HAJA 3Q0KA 3HAIA 3LLLA 3SOGA 4ATMA 2X3WA 5C5BB 1I4LA 4WPEA 3ACOA 2Q12A 2RAKA 3ABHA 1URUA 4NSWA 4FZSA 3G9GA 4DCNC 2X3VA 3M3WA 3QWEA 4NQIA
chains in the Genus database with same CATH superfamily
3BUQA 1R5EA 3BVXA 2Z0NA 4R5JA 1U00A 3BVWA 5TKYA 2YLAA 1O7DC 3SOGA 4JNFA 4FZPA 4WPEA 1QWNA 3KAWA 3M3WA 3L3OM 2PMRA 2MI7A 1R33A 1GNTA 2D1LA 3F7WA 2EX3B 1OA1A 3VKHA 3FD9A 3BLBA 3O3NB 4JN4A 1URUA 3UITA 2F7RA 1ZYLA 4EZYA 2Q13A 3DX0A 1QX1A 4R5KA 1DKZA 3I01A 1X04A 2X5CA 3SYVA 4EZZA 4JWEA 4AZHA 1I4DA 3OK8A 4KIKB 3T49A 2LXYA 3CZSA 2YIVX 3ACOA 2ZXQA 3D2FA 3VEBA 2WYHA 3GI7A 2EFLA 2Z0VA 4R5GA 4H6IA 1TQWA 2OBLA 1SU6A 4G6QA 2JNKA 2RT6A 2ALWA 3DX4A 1TQVA 3DPOA 1LQ7A 2ND1A 5KBPA 2RAKA 1MJGA 1HXKA 2YL8A 3D50A 4EZNA 3BVVA 3QA8A 2EFKA 2OBMA 2RAIA 1W9MA 3ER9B 2Z8YA 4EZPA 3T48A 1PS3A 4EZUA 3EJPA 5FIGA 4E81A 4UDYX 2F1AA 4FZOA 3RV1A 3Q84A 3DPQA 3DX3A 3DDFA 3QE6A 3O3MB 4H6HA 1HTYA 3PLTA 2WINM 2OW6A 4IM3A 3CKDA 2N3KA 3BUDA 3QWEA 4JWIA 2QKWA 3B51X 1Y2OA 3DDGA 1QWUA 3ER8C 4AVMA 1SU7A 3DPPA 3BUIA 4HY9A 4H8SA 3B53X 2X3XA 3EJSA 2F1BA 3QNIA 2YLLA 2F7OA 2QXLA 3BUBA 3HAHA 1WDZA 4F00A 2Z0OA 4F01A 3HAJA 4ATMA 2F7QA 2OW7A 4AZ7A 1O7DB 3EJRA 1DKXA 4UDXX 4AZ5A 1UPXA 4I1QA 3CZNA 4R5LA 3VEAA 4WPCA 2PY6A 3KAVA 2OO2A 4EZTA 4D8JA 2YIAA 2F7PA 4HR1B 2Q12A 4NSWA 4JWCA 4PO2A 2FYVA 4NQIA 3A98A 1E9VA 1X03A 4KIKA 1JQKA 3D51A 3LMFA 2OZNB 4IWOA 4AZBA 2LM0A 3B52X 3D4YA 1ZWWA 2O0I1 3D4ZA 2YL6A 2YI8A 2C08A 4JWDA 3DX1A 1E2UA 1DKYA 4IW0A 3I04A 1I4TA 1HWWA 3LVTA 2YKTA 4NPHA 4HR1A 2GA9D 1GN9A 2GAFD 4AZCB 3DYTA 3T4AG 1TQTA 4IWPA 1E1DA 3O3OB 2ND0A 1GNLA 2YL9A 2QFFA 4JLCA 2GF4A 4DYLA 4FM3A 3ERCC 3RV0A 3I2WA 5C5BB 1I4LA 4AZCA 4HYBA 4E3CA 1TQSA 4EZSA 3C7NA 4AKVA 3KDRA 3EJUA 3RPMA 3I39X 2ELBA 3Q0KA 3LLLA 4IM2A 1OA0A 3EJQA 3ABHA 2KHOA 4JNEA 4AZ6A 3QNJA 4EZXA 5E84A 3L3PA 4AZGA 5C5BA 4EZOA 2YIBA 4B9QA 3T47A 4R5IA 1OAOA 4FZSA 3G9GA 4DCNC 4EZVA 2X3VA 4AZIA 3OWGA 4M0MA 1I49A 2V0OA 2WYIA 1TQUA 3D52A 2YI9A 4BNEA 3DX2A 3ZEDA 1SU8A 3BUPA 3D2EA 3T46A 4JL9A 3HAIA 2F18A 4EZRA 3OHXM 2NCZA 2RAJA 3CVRA 4IM0A 1R34A 3CAZA 3EJTA 4EZWA 3CV5A 4EZQA 2YL5A 3BVUA 2JNSA 2FICA 2D4CA 2EWFA 5FLEX 3BVTA 2X3WA 4IWQA 1SUFA 1YWMA
chains in the Genus database with same CATH topology
2Q13A 4H8SA 1X03A 2RAJA 1I49A 2Z0NA 2EFLA 2V0OA 2Z0VA 4AKVA 1I4TA 3Q84A 3CAZA 1Y2OA 2EFKA 2YKTA 2X3XA 2RAIA 4DYLA 4I1QA 5C5BA 1X04A 3SYVA 4BNEA 4WPCA 3QE6A 3QNIA 1I4DA 4AVMA 2FICA 3OK8A 1ZWWA 3DYTA 3HAHA 2D4CA 1WDZA 2D1LA 2Z0OA 3PLTA 2C08A 3I2WA 2ELBA 3HAJA 3Q0KA 3HAIA 3LLLA 3SOGA 4ATMA 2X3WA 5C5BB 1I4LA 4WPEA 3ACOA 2Q12A 2RAKA 3ABHA 1URUA 4NSWA 4FZSA 3G9GA 4DCNC 2X3VA 3M3WA 3QWEA 4NQIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q13 A;  4H8S A;  1X03 A;  2RAJ A;  1I49 A;  2Z0N A;  2EFL A;  2V0O A;  2Z0V A;  4AKV A;  1I4T A;  3Q84 A;  3CAZ A;  1Y2O A;  2EFK A;  2YKT A;  2X3X A;  2RAI A;  4DYL A;  4I1Q A;  5C5B A;  1X04 A;  3SYV A;  4BNE A;  4WPC A;  3QE6 A;  3QNI A;  1I4D A;  4AVM A;  2FIC A;  3OK8 A;  1ZWW A;  3DYT A;  3HAH A;  2D4C A;  1WDZ A;  2D1L A;  2Z0O A;  3PLT A;  2C08 A;  3I2W A;  2ELB A;  3HAJ A;  3Q0K A;  3HAI A;  3LLL A;  3SOG A;  4ATM A;  2X3W A;  5C5B B;  1I4L A;  4WPE A;  3ACO A;  2Q12 A;  2RAK A;  3ABH A;  1URU A;  4NSW A;  4FZS A;  3G9G A;  4DCN C;  2X3V A;  3M3W A;  3QWE A;  4NQI A; 
#chains in the Genus database with same CATH topology
 3BUQ A;  1R5E A;  3BVX A;  2Z0N A;  4R5J A;  1U00 A;  3BVW A;  5TKY A;  2YLA A;  1O7D C;  3SOG A;  4JNF A;  4FZP A;  4WPE A;  1QWN A;  3KAW A;  3M3W A;  3L3O M;  2PMR A;  2MI7 A;  1R33 A;  1GNT A;  2D1L A;  3F7W A;  2EX3 B;  1OA1 A;  3VKH A;  3FD9 A;  3BLB A;  3O3N B;  4JN4 A;  1URU A;  3UIT A;  2F7R A;  1ZYL A;  4EZY A;  2Q13 A;  3DX0 A;  1QX1 A;  4R5K A;  1DKZ A;  3I01 A;  1X04 A;  2X5C A;  3SYV A;  4EZZ A;  4JWE A;  4AZH A;  1I4D A;  3OK8 A;  4KIK B;  3T49 A;  2LXY A;  3CZS A;  2YIV X;  3ACO A;  2ZXQ A;  3D2F A;  3VEB A;  2WYH A;  3GI7 A;  2EFL A;  2Z0V A;  4R5G A;  4H6I A;  1TQW A;  2OBL A;  1SU6 A;  4G6Q A;  2JNK A;  2RT6 A;  2ALW A;  3DX4 A;  1TQV A;  3DPO A;  1LQ7 A;  2ND1 A;  5KBP A;  2RAK A;  1MJG A;  1HXK A;  2YL8 A;  3D50 A;  4EZN A;  3BVV A;  3QA8 A;  2EFK A;  2OBM A;  2RAI A;  1W9M A;  3ER9 B;  2Z8Y A;  4EZP A;  3T48 A;  1PS3 A;  4EZU A;  3EJP A;  5FIG A;  4E81 A;  4UDY X;  2F1A A;  4FZO A;  3RV1 A;  3Q84 A;  3DPQ A;  3DX3 A;  3DDF A;  3QE6 A;  3O3M B;  4H6H A;  1HTY A;  3PLT A;  2WIN M;  2OW6 A;  4IM3 A;  3CKD A;  2N3K A;  3BUD A;  3QWE A;  4JWI A;  2QKW A;  3B51 X;  1Y2O A;  3DDG A;  1QWU A;  3ER8 C;  4AVM A;  1SU7 A;  3DPP A;  3BUI A;  4HY9 A;  4H8S A;  3B53 X;  2X3X A;  3EJS A;  2F1B A;  3QNI A;  2YLL A;  2F7O A;  2QXL A;  3BUB A;  3HAH A;  1WDZ A;  4F00 A;  2Z0O A;  4F01 A;  3HAJ A;  4ATM A;  2F7Q A;  2OW7 A;  4AZ7 A;  1O7D B;  3EJR A;  1DKX A;  4UDX X;  4AZ5 A;  1UPX A;  4I1Q A;  3CZN A;  4R5L A;  3VEA A;  4WPC A;  2PY6 A;  3KAV A;  2OO2 A;  4EZT A;  4D8J A;  2YIA A;  2F7P A;  4HR1 B;  2Q12 A;  4NSW A;  4JWC A;  4PO2 A;  2FYV A;  4NQI A;  3A98 A;  1E9V A;  1X03 A;  4KIK A;  1JQK A;  3D51 A;  3LMF A;  2OZN B;  4IWO A;  4AZB A;  2LM0 A;  3B52 X;  3D4Y A;  1ZWW A;  2O0I 1;  3D4Z A;  2YL6 A;  2YI8 A;  2C08 A;  4JWD A;  3DX1 A;  1E2U A;  1DKY A;  4IW0 A;  3I04 A;  1I4T A;  1HWW A;  3LVT A;  2YKT A;  4NPH A;  4HR1 A;  2GA9 D;  1GN9 A;  2GAF D;  4AZC B;  3DYT A;  3T4A G;  1TQT A;  4IWP A;  1E1D A;  3O3O B;  2ND0 A;  1GNL A;  2YL9 A;  2QFF A;  4JLC A;  2GF4 A;  4DYL A;  4FM3 A;  3ERC C;  3RV0 A;  3I2W A;  5C5B B;  1I4L A;  4AZC A;  4HYB A;  4E3C A;  1TQS A;  4EZS A;  3C7N A;  4AKV A;  3KDR A;  3EJU A;  3RPM A;  3I39 X;  2ELB A;  3Q0K A;  3LLL A;  4IM2 A;  1OA0 A;  3EJQ A;  3ABH A;  2KHO A;  4JNE A;  4AZ6 A;  3QNJ A;  4EZX A;  5E84 A;  3L3P A;  4AZG A;  5C5B A;  4EZO A;  2YIB A;  4B9Q A;  3T47 A;  4R5I A;  1OAO A;  4FZS A;  3G9G A;  4DCN C;  4EZV A;  2X3V A;  4AZI A;  3OWG A;  4M0M A;  1I49 A;  2V0O A;  2WYI A;  1TQU A;  3D52 A;  2YI9 A;  4BNE A;  3DX2 A;  3ZED A;  1SU8 A;  3BUP A;  3D2E A;  3T46 A;  4JL9 A;  3HAI A;  2F18 A;  4EZR A;  3OHX M;  2NCZ A;  2RAJ A;  3CVR A;  4IM0 A;  1R34 A;  3CAZ A;  3EJT A;  4EZW A;  3CV5 A;  4EZQ A;  2YL5 A;  3BVU A;  2JNS A;  2FIC A;  2D4C A;  2EWF A;  5FLE X;  3BVT A;  2X3W A;  4IWQ A;  1SUF A;  1YWM A; 
#chains in the Genus database with same CATH homology
 2Q13 A;  4H8S A;  1X03 A;  2RAJ A;  1I49 A;  2Z0N A;  2EFL A;  2V0O A;  2Z0V A;  4AKV A;  1I4T A;  3Q84 A;  3CAZ A;  1Y2O A;  2EFK A;  2YKT A;  2X3X A;  2RAI A;  4DYL A;  4I1Q A;  5C5B A;  1X04 A;  3SYV A;  4BNE A;  4WPC A;  3QE6 A;  3QNI A;  1I4D A;  4AVM A;  2FIC A;  3OK8 A;  1ZWW A;  3DYT A;  3HAH A;  2D4C A;  1WDZ A;  2D1L A;  2Z0O A;  3PLT A;  2C08 A;  3I2W A;  2ELB A;  3HAJ A;  3Q0K A;  3HAI A;  3LLL A;  3SOG A;  4ATM A;  2X3W A;  5C5B B;  1I4L A;  4WPE A;  3ACO A;  2Q12 A;  2RAK A;  3ABH A;  1URU A;  4NSW A;  4FZS A;  3G9G A;  4DCN C;  2X3V A;  3M3W A;  3QWE A;  4NQI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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