3ACOA

Crystal structure of the efc/f-bar domain of human pacsin2/syndapin ii (2.7 a)
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
284
structure length
284
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II
pubmed doi rcsb
molecule tags Endocytosis
source organism Homo sapiens
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 101
structure length 284
sequence length 284
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3acoA01
3ABHA 2EFKA 3DYTA 3OK8A 1WDZA 2RAKA 2Z0VA 3QNIA 3QWEA 2Z0NA 4I1QA 4DYLA 2Q12A 2ELBA 1X04A 2V0OA 2Z0OA 4BNEA 5C5BB 4WPCA 4WPEA 2X3WA 4H8SA 5C5BA 1I49A 3I2WA 2Q13A 3Q0KA 2X3VA 1I4LA 1URUA 2YKTA 3CAZA 4FZSA 3PLTA 1Y2OA 4DCNC 2RAIA 3LLLA 3HAIA 3Q84A 4ATMA 4NSWA 2EFLA 1I4DA 3HAJA 3SYVA 4AVMA 3M3WA 2D4CA 1I4TA 1X03A 1ZWWA 2FICA 3G9GA 2C08A 3QE6A 4NQIA 2X3XA 3HAHA 4AKVA 2D1LA 2RAJA 3SOGA 3ACOA
chains in the Genus database with same CATH superfamily
4EZSA 2YL6A 3DX3A 4AZGA 3GI7A 2OW6A 2X5CA 4EZYA 2ND1A 1MJGA 4IWPA 3T4AG 3BUIA 1E2UA 1GNLA 4NPHA 3BUQA 3B51X 1ZWWA 3O3OB 2O0I1 3VKHA 4R5LA 2YLLA 3QNIA 4G6QA 2V0OA 2LXYA 3T48A 2NCZA 1GN9A 2N3KA 3CVRA 2WYHA 2FICA 4HR1B 2OZNB 1OA1A 1O7DC 4KIKB 3F7WA 2OW7A 4DYLA 2YL9A 1ZYLA 3D4ZA 2Q12A 4JWDA 3D51A 4H8SA 3D2EA 3BVTA 3CAZA 4IM3A 4PO2A 3DX1A 3OHXM 4ATMA 3EJTA 3BUBA 3SYVA 3DX4A 1I4TA 2X3XA 2ALWA 2F1AA 3DYTA 4FZOA 2F7PA 2Z0OA 4H6HA 5C5BA 1QX1A 1I49A 1R33A 3I2WA 3QNJA 4D8JA 2LM0A 2OBLA 4R5GA 4AZHA 1R5EA 4AVMA 4UDYX 4NQIA 3A98A 3BVVA 3KAWA 4WPCA 2GA9D 3LVTA 3O3MB 4R5KA 2GF4A 3BUDA 2ND0A 4AZBA 3OWGA 4UDXX 3I04A 4AZ6A 4EZRA 4EZTA 3G9GA 4JL9A 3DPOA 2RAJA 1QWNA 3L3OM 4I1QA 3BVWA 4EZNA 3ERCC 3D52A 5TKYA 3VEBA 3D50A 3B52X 3EJSA 3QA8A 3M3WA 2D4CA 1HXKA 2PY6A 2YL5A 4EZVA 1HWWA 1LQ7A 2F7QA 1YWMA 2F18A 5C5BB 1DKYA 4AZIA 3O3NB 3Q0KA 4EZQA 5E84A 1TQSA 2ZXQA 4H6IA 1TQUA 1R34A 3EJUA 3I01A 2YI9A 3EJPA 3DX2A 3OK8A 4AZ5A 4IWOA 3RPMA 2EX3B 1OAOA 3CV5A 2Q13A 3DX0A 1I4LA 1E9VA 1URUA 1TQVA 1HTYA 3HAJA 2GAFD 1O7DB 2QXLA 4IM2A 4HY9A 3SOGA 1JQKA 2JNSA 4AZCA 4JLCA 3ZEDA 3DPPA 3DDFA 4EZZA 4JWIA 5KBPA 3C7NA 2D1LA 4FZPA 3ABHA 4IM0A 3KAVA 1WDZA 3UITA 1U00A 5FIGA 4M0MA 4F00A 2Z8YA 3BLBA 2RT6A 1Y2OA 2F1BA 4EZOA 2FYVA 4F01A 4JNFA 2YLAA 4FM3A 4KIKA 4JN4A 2Z0NA 1QWUA 4E81A 3BVUA 1W9MA 3I39X 2OO2A 3EJQA 3D4YA 2YIAA 1SU7A 2F7OA 1UPXA 4DCNC 4AZCB 2RAKA 2WYIA 3ER8C 2X3WA 2KHOA 5FLEX 1TQWA 3RV0A 4EZWA 3EJRA 3LLLA 2PMRA 2MI7A 1SUFA 1DKXA 3T49A 3QE6A 3KDRA 3RV1A 2F7RA 2YI8A 4B9QA 4BNEA 1GNTA 4EZUA 2QKWA 3CZSA 3Q84A 2EFLA 3VEAA 2JNKA 1X03A 2C08A 3HAHA 4IWQA 2Z0VA 4JWCA 4R5IA 4HYBA 4R5JA 4WPEA 1DKZA 1SU6A 4JNEA 2RAIA 3CKDA 4NSWA 2YIVX 1I4DA 4EZPA 4E3CA 2EWFA 2OBMA 3L3PA 3ER9B 1SU8A 3BUPA 4AZ7A 3QWEA 2YIBA 1PS3A 3DPQA 3D2FA 1E1DA 4FZSA 4EZXA 3HAIA 2QFFA 3FD9A 2WINM 3CZNA 4HR1A 3B53X 2EFKA 3DDGA 3T46A 1X04A 2ELBA 4IW0A 4JWEA 2YL8A 2X3VA 1TQTA 2YKTA 3LMFA 3PLTA 3BVXA 1OA0A 3T47A 4AKVA 3ACOA
chains in the Genus database with same CATH topology
3ABHA 2EFKA 3DYTA 3OK8A 1WDZA 2RAKA 2Z0VA 3QNIA 3QWEA 2Z0NA 4I1QA 4DYLA 2Q12A 2ELBA 1X04A 2V0OA 2Z0OA 4BNEA 5C5BB 4WPCA 4WPEA 2X3WA 4H8SA 5C5BA 1I49A 3I2WA 2Q13A 3Q0KA 2X3VA 1I4LA 1URUA 2YKTA 3CAZA 4FZSA 3PLTA 1Y2OA 4DCNC 2RAIA 3LLLA 3HAIA 3Q84A 4ATMA 4NSWA 2EFLA 1I4DA 3HAJA 3SYVA 4AVMA 3M3WA 2D4CA 1I4TA 1X03A 1ZWWA 2FICA 3G9GA 2C08A 3QE6A 4NQIA 2X3XA 3HAHA 4AKVA 2D1LA 2RAJA 3SOGA 3ACOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ABH A;  2EFK A;  3DYT A;  3OK8 A;  1WDZ A;  2RAK A;  2Z0V A;  3QNI A;  3QWE A;  2Z0N A;  4I1Q A;  4DYL A;  2Q12 A;  2ELB A;  1X04 A;  2V0O A;  2Z0O A;  4BNE A;  5C5B B;  4WPC A;  4WPE A;  2X3W A;  4H8S A;  5C5B A;  1I49 A;  3I2W A;  2Q13 A;  3Q0K A;  2X3V A;  1I4L A;  1URU A;  2YKT A;  3CAZ A;  4FZS A;  3PLT A;  1Y2O A;  4DCN C;  2RAI A;  3LLL A;  3HAI A;  3Q84 A;  4ATM A;  4NSW A;  2EFL A;  1I4D A;  3HAJ A;  3SYV A;  4AVM A;  3M3W A;  2D4C A;  1I4T A;  1X03 A;  1ZWW A;  2FIC A;  3G9G A;  2C08 A;  3QE6 A;  4NQI A;  2X3X A;  3HAH A;  4AKV A;  2D1L A;  2RAJ A;  3SOG A;  3ACO A; 
#chains in the Genus database with same CATH topology
 4EZS A;  2YL6 A;  3DX3 A;  4AZG A;  3GI7 A;  2OW6 A;  2X5C A;  4EZY A;  2ND1 A;  1MJG A;  4IWP A;  3T4A G;  3BUI A;  1E2U A;  1GNL A;  4NPH A;  3BUQ A;  3B51 X;  1ZWW A;  3O3O B;  2O0I 1;  3VKH A;  4R5L A;  2YLL A;  3QNI A;  4G6Q A;  2V0O A;  2LXY A;  3T48 A;  2NCZ A;  1GN9 A;  2N3K A;  3CVR A;  2WYH A;  2FIC A;  4HR1 B;  2OZN B;  1OA1 A;  1O7D C;  4KIK B;  3F7W A;  2OW7 A;  4DYL A;  2YL9 A;  1ZYL A;  3D4Z A;  2Q12 A;  4JWD A;  3D51 A;  4H8S A;  3D2E A;  3BVT A;  3CAZ A;  4IM3 A;  4PO2 A;  3DX1 A;  3OHX M;  4ATM A;  3EJT A;  3BUB A;  3SYV A;  3DX4 A;  1I4T A;  2X3X A;  2ALW A;  2F1A A;  3DYT A;  4FZO A;  2F7P A;  2Z0O A;  4H6H A;  5C5B A;  1QX1 A;  1I49 A;  1R33 A;  3I2W A;  3QNJ A;  4D8J A;  2LM0 A;  2OBL A;  4R5G A;  4AZH A;  1R5E A;  4AVM A;  4UDY X;  4NQI A;  3A98 A;  3BVV A;  3KAW A;  4WPC A;  2GA9 D;  3LVT A;  3O3M B;  4R5K A;  2GF4 A;  3BUD A;  2ND0 A;  4AZB A;  3OWG A;  4UDX X;  3I04 A;  4AZ6 A;  4EZR A;  4EZT A;  3G9G A;  4JL9 A;  3DPO A;  2RAJ A;  1QWN A;  3L3O M;  4I1Q A;  3BVW A;  4EZN A;  3ERC C;  3D52 A;  5TKY A;  3VEB A;  3D50 A;  3B52 X;  3EJS A;  3QA8 A;  3M3W A;  2D4C A;  1HXK A;  2PY6 A;  2YL5 A;  4EZV A;  1HWW A;  1LQ7 A;  2F7Q A;  1YWM A;  2F18 A;  5C5B B;  1DKY A;  4AZI A;  3O3N B;  3Q0K A;  4EZQ A;  5E84 A;  1TQS A;  2ZXQ A;  4H6I A;  1TQU A;  1R34 A;  3EJU A;  3I01 A;  2YI9 A;  3EJP A;  3DX2 A;  3OK8 A;  4AZ5 A;  4IWO A;  3RPM A;  2EX3 B;  1OAO A;  3CV5 A;  2Q13 A;  3DX0 A;  1I4L A;  1E9V A;  1URU A;  1TQV A;  1HTY A;  3HAJ A;  2GAF D;  1O7D B;  2QXL A;  4IM2 A;  4HY9 A;  3SOG A;  1JQK A;  2JNS A;  4AZC A;  4JLC A;  3ZED A;  3DPP A;  3DDF A;  4EZZ A;  4JWI A;  5KBP A;  3C7N A;  2D1L A;  4FZP A;  3ABH A;  4IM0 A;  3KAV A;  1WDZ A;  3UIT A;  1U00 A;  5FIG A;  4M0M A;  4F00 A;  2Z8Y A;  3BLB A;  2RT6 A;  1Y2O A;  2F1B A;  4EZO A;  2FYV A;  4F01 A;  4JNF A;  2YLA A;  4FM3 A;  4KIK A;  4JN4 A;  2Z0N A;  1QWU A;  4E81 A;  3BVU A;  1W9M A;  3I39 X;  2OO2 A;  3EJQ A;  3D4Y A;  2YIA A;  1SU7 A;  2F7O A;  1UPX A;  4DCN C;  4AZC B;  2RAK A;  2WYI A;  3ER8 C;  2X3W A;  2KHO A;  5FLE X;  1TQW A;  3RV0 A;  4EZW A;  3EJR A;  3LLL A;  2PMR A;  2MI7 A;  1SUF A;  1DKX A;  3T49 A;  3QE6 A;  3KDR A;  3RV1 A;  2F7R A;  2YI8 A;  4B9Q A;  4BNE A;  1GNT A;  4EZU A;  2QKW A;  3CZS A;  3Q84 A;  2EFL A;  3VEA A;  2JNK A;  1X03 A;  2C08 A;  3HAH A;  4IWQ A;  2Z0V A;  4JWC A;  4R5I A;  4HYB A;  4R5J A;  4WPE A;  1DKZ A;  1SU6 A;  4JNE A;  2RAI A;  3CKD A;  4NSW A;  2YIV X;  1I4D A;  4EZP A;  4E3C A;  2EWF A;  2OBM A;  3L3P A;  3ER9 B;  1SU8 A;  3BUP A;  4AZ7 A;  3QWE A;  2YIB A;  1PS3 A;  3DPQ A;  3D2F A;  1E1D A;  4FZS A;  4EZX A;  3HAI A;  2QFF A;  3FD9 A;  2WIN M;  3CZN A;  4HR1 A;  3B53 X;  2EFK A;  3DDG A;  3T46 A;  1X04 A;  2ELB A;  4IW0 A;  4JWE A;  2YL8 A;  2X3V A;  1TQT A;  2YKT A;  3LMF A;  3PLT A;  3BVX A;  1OA0 A;  3T47 A;  4AKV A;  3ACO A; 
#chains in the Genus database with same CATH homology
 3ABH A;  2EFK A;  3DYT A;  3OK8 A;  1WDZ A;  2RAK A;  2Z0V A;  3QNI A;  3QWE A;  2Z0N A;  4I1Q A;  4DYL A;  2Q12 A;  2ELB A;  1X04 A;  2V0O A;  2Z0O A;  4BNE A;  5C5B B;  4WPC A;  4WPE A;  2X3W A;  4H8S A;  5C5B A;  1I49 A;  3I2W A;  2Q13 A;  3Q0K A;  2X3V A;  1I4L A;  1URU A;  2YKT A;  3CAZ A;  4FZS A;  3PLT A;  1Y2O A;  4DCN C;  2RAI A;  3LLL A;  3HAI A;  3Q84 A;  4ATM A;  4NSW A;  2EFL A;  1I4D A;  3HAJ A;  3SYV A;  4AVM A;  3M3W A;  2D4C A;  1I4T A;  1X03 A;  1ZWW A;  2FIC A;  3G9G A;  2C08 A;  3QE6 A;  4NQI A;  2X3X A;  3HAH A;  4AKV A;  2D1L A;  2RAJ A;  3SOG A;  3ACO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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