3ACOA

Crystal structure of the efc/f-bar domain of human pacsin2/syndapin ii (2.7 a)
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
284
structure length
284
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Protein kinase C and casein kinase substrate in neurons prot
publication title Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II
pubmed doi rcsb
source organism Homo sapiens
molecule tags Endocytosis
total genus 101
structure length 284
sequence length 284
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3acoA01
2Q12A 2RAKA 3CAZA 3PLTA 4H8SA 3Q0KA 3QNIA 4WPEA 3HAJA 3HAIA 2EFKA 2C08A 1X03A 3M3WA 2RAIA 3QWEA 3DYTA 2FICA 4BNEA 4ATMA 2Q13A 4I1QA 1ZWWA 1URUA 2YKTA 5C5BA 4AKVA 2RAJA 1Y2OA 2ELBA 3ABHA 3OK8A 2X3WA 4WPCA 3SOGA 1I49A 1I4LA 1WDZA 3LLLA 3Q84A 4DCNC 2X3XA 3ACOA 2D4CA 4FZSA 3QE6A 5C5BB 4NSWA 2D1LA 2V0OA 4AVMA 1I4TA 2EFLA 2Z0OA 3HAHA 1I4DA 4NQIA 3G9GA 4DYLA 2X3VA 2Z0VA 3SYVA 1X04A 3I2WA 2Z0NA
chains in the Genus database with same CATH superfamily
4AZCB 2RAIA 3QWEA 1OA0A 4BNEA 2LM0A 3OK8A 5FLEX 3OHXM 3BUQA 3RV1A 4KIKA 4JL9A 3DPPA 3B51X 4AZHA 1OA1A 2Z8YA 3ER8C 3M3WA 3DX2A 4ATMA 1I4LA 2EWFA 4IWQA 2WYHA 4FZPA 2EX3B 1O7DB 1E1DA 3O3MB 3ER9B 3QA8A 1R33A 2Q13A 3CVRA 2ND1A 2GAFD 3O3OB 3BUIA 2PMRA 3D52A 5C5BB 3GI7A 4R5LA 2Q12A 2YL8A 3CAZA 4FZOA 2EFKA 3EJPA 2F7RA 4EZUA 3BLBA 2YI8A 3T48A 2F7QA 1TQVA 2YIVX 2OW7A 4E81A 4UDYX 3T4AG 3D4YA 3UITA 1TQTA 2F1AA 5FIGA 4IM0A 1MJGA 1QWNA 1SUFA 3I39X 4EZVA 2F7OA 3SOGA 4HR1A 2ALWA 2ND0A 2YIAA 3DPOA 4AVMA 2Z0OA 3HAHA 1I4DA 4IWOA 1O7DC 1GN9A 4H6HA 2RAKA 2ZXQA 4D8JA 2OBMA 4R5IA 4EZPA 1TQSA 3DX4A 2RT6A 3QNJA 2F7PA 2WYIA 2V0OA 5TKYA 2F1BA 2Z0VA 4M0MA 2YL9A 2QKWA 3VEBA 4H8SA 4JLCA 2YLLA 1W9MA 3DX0A 3BVWA 1ZWWA 2YKTA 4H6IA 4JWCA 2ELBA 4AZ6A 3LVTA 1U00A 4WPCA 2OZNB 2GF4A 3ACOA 4FZSA 3CZSA 4EZZA 3BVTA 1DKXA 3ZEDA 2YL5A 4UDXX 3DYTA 4E3CA 4AKVA 2RAJA 3ABHA 1SU6A 4AZIA 3Q84A 4IM3A 3CKDA 4NSWA 4B9QA 2KHOA 1PS3A 4R5JA 1QX1A 3PLTA 3T46A 2C08A 3CV5A 3BVXA 2JNKA 4R5GA 4EZNA 1URUA 4PO2A 1TQUA 3D2FA 2F18A 3T49A 3ERCC 2NCZA 1GNLA 3D51A 1SU8A 4EZTA 2EFLA 1E9VA 2Z0NA 1TQWA 3DX3A 4KIKB 4HYBA 4NPHA 3OWGA 4JWIA 4I1QA 1Y2OA 4R5KA 2QXLA 2D4CA 2OW6A 3EJRA 4NQIA 4JN4A 3KAVA 2YI9A 4WPEA 3DDFA 2LXYA 3KDRA 4EZOA 3EJUA 5C5BA 4HY9A 2JNSA 3RV0A 1JQKA 1YWMA 4F01A 4F00A 4EZQA 3G9GA 3I2WA 1DKYA 2FYVA 3I04A 3HAJA 3HAIA 3EJTA 4EZWA 2FICA 2QFFA 4FM3A 3B52X 1I49A 3EJQA 3LLLA 1HXKA 4JNFA 3RPMA 3D50A 4JNEA 4AZGA 2MI7A 1HWWA 3DPQA 4IM2A 1R5EA 2OBLA 3L3OM 2X5CA 5E84A 3I01A 3EJSA 2X3WA 3KAWA 3CZNA 3L3PA 1I4TA 4AZCA 4JWDA 4HR1B 3VKHA 4G6QA 3QNIA 4IW0A 4EZSA 4AZ5A 3D4ZA 2N3KA 2YLAA 3BVVA 1LQ7A 3DDGA 4DYLA 5KBPA 2OO2A 3LMFA 3B53X 1GNTA 3Q0KA 1DKZA 4AZ7A 3F7WA 1X03A 3D2EA 3O3NB 2YL6A 3BUDA 3BUPA 1HTYA 4EZRA 1OAOA 2X3XA 4AZBA 2D1LA 2PY6A 2YIBA 1R34A 3BVUA 4IWPA 2X3VA 3A98A 3SYVA 1X04A 3FD9A 3BUBA 1E2UA 4EZYA 1UPXA 1ZYLA 2GA9D 2O0I1 3VEAA 4JWEA 1WDZA 4EZXA 4DCNC 3QE6A 2WINM 1QWUA 1SU7A 3DX1A 3C7NA 3T47A
chains in the Genus database with same CATH topology
2Q12A 2RAKA 3CAZA 3PLTA 4H8SA 3Q0KA 3QNIA 4WPEA 3HAJA 3HAIA 2EFKA 2C08A 1X03A 3M3WA 2RAIA 3QWEA 3DYTA 2FICA 4BNEA 4ATMA 2Q13A 4I1QA 1ZWWA 1URUA 2YKTA 5C5BA 4AKVA 2RAJA 1Y2OA 2ELBA 3ABHA 3OK8A 2X3WA 4WPCA 3SOGA 1I49A 1I4LA 1WDZA 3LLLA 3Q84A 4DCNC 2X3XA 3ACOA 2D4CA 4FZSA 3QE6A 5C5BB 4NSWA 2D1LA 2V0OA 4AVMA 1I4TA 2EFLA 2Z0OA 3HAHA 1I4DA 4NQIA 3G9GA 4DYLA 2X3VA 2Z0VA 3SYVA 1X04A 3I2WA 2Z0NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q12 A;  2RAK A;  3CAZ A;  3PLT A;  4H8S A;  3Q0K A;  3QNI A;  4WPE A;  3HAJ A;  3HAI A;  2EFK A;  2C08 A;  1X03 A;  3M3W A;  2RAI A;  3QWE A;  3DYT A;  2FIC A;  4BNE A;  4ATM A;  2Q13 A;  4I1Q A;  1ZWW A;  1URU A;  2YKT A;  5C5B A;  4AKV A;  2RAJ A;  1Y2O A;  2ELB A;  3ABH A;  3OK8 A;  2X3W A;  4WPC A;  3SOG A;  1I49 A;  1I4L A;  1WDZ A;  3LLL A;  3Q84 A;  4DCN C;  2X3X A;  3ACO A;  2D4C A;  4FZS A;  3QE6 A;  5C5B B;  4NSW A;  2D1L A;  2V0O A;  4AVM A;  1I4T A;  2EFL A;  2Z0O A;  3HAH A;  1I4D A;  4NQI A;  3G9G A;  4DYL A;  2X3V A;  2Z0V A;  3SYV A;  1X04 A;  3I2W A;  2Z0N A; 
#chains in the Genus database with same CATH topology
 4AZC B;  2RAI A;  3QWE A;  1OA0 A;  4BNE A;  2LM0 A;  3OK8 A;  5FLE X;  3OHX M;  3BUQ A;  3RV1 A;  4KIK A;  4JL9 A;  3DPP A;  3B51 X;  4AZH A;  1OA1 A;  2Z8Y A;  3ER8 C;  3M3W A;  3DX2 A;  4ATM A;  1I4L A;  2EWF A;  4IWQ A;  2WYH A;  4FZP A;  2EX3 B;  1O7D B;  1E1D A;  3O3M B;  3ER9 B;  3QA8 A;  1R33 A;  2Q13 A;  3CVR A;  2ND1 A;  2GAF D;  3O3O B;  3BUI A;  2PMR A;  3D52 A;  5C5B B;  3GI7 A;  4R5L A;  2Q12 A;  2YL8 A;  3CAZ A;  4FZO A;  2EFK A;  3EJP A;  2F7R A;  4EZU A;  3BLB A;  2YI8 A;  3T48 A;  2F7Q A;  1TQV A;  2YIV X;  2OW7 A;  4E81 A;  4UDY X;  3T4A G;  3D4Y A;  3UIT A;  1TQT A;  2F1A A;  5FIG A;  4IM0 A;  1MJG A;  1QWN A;  1SUF A;  3I39 X;  4EZV A;  2F7O A;  3SOG A;  4HR1 A;  2ALW A;  2ND0 A;  2YIA A;  3DPO A;  4AVM A;  2Z0O A;  3HAH A;  1I4D A;  4IWO A;  1O7D C;  1GN9 A;  4H6H A;  2RAK A;  2ZXQ A;  4D8J A;  2OBM A;  4R5I A;  4EZP A;  1TQS A;  3DX4 A;  2RT6 A;  3QNJ A;  2F7P A;  2WYI A;  2V0O A;  5TKY A;  2F1B A;  2Z0V A;  4M0M A;  2YL9 A;  2QKW A;  3VEB A;  4H8S A;  4JLC A;  2YLL A;  1W9M A;  3DX0 A;  3BVW A;  1ZWW A;  2YKT A;  4H6I A;  4JWC A;  2ELB A;  4AZ6 A;  3LVT A;  1U00 A;  4WPC A;  2OZN B;  2GF4 A;  3ACO A;  4FZS A;  3CZS A;  4EZZ A;  3BVT A;  1DKX A;  3ZED A;  2YL5 A;  4UDX X;  3DYT A;  4E3C A;  4AKV A;  2RAJ A;  3ABH A;  1SU6 A;  4AZI A;  3Q84 A;  4IM3 A;  3CKD A;  4NSW A;  4B9Q A;  2KHO A;  1PS3 A;  4R5J A;  1QX1 A;  3PLT A;  3T46 A;  2C08 A;  3CV5 A;  3BVX A;  2JNK A;  4R5G A;  4EZN A;  1URU A;  4PO2 A;  1TQU A;  3D2F A;  2F18 A;  3T49 A;  3ERC C;  2NCZ A;  1GNL A;  3D51 A;  1SU8 A;  4EZT A;  2EFL A;  1E9V A;  2Z0N A;  1TQW A;  3DX3 A;  4KIK B;  4HYB A;  4NPH A;  3OWG A;  4JWI A;  4I1Q A;  1Y2O A;  4R5K A;  2QXL A;  2D4C A;  2OW6 A;  3EJR A;  4NQI A;  4JN4 A;  3KAV A;  2YI9 A;  4WPE A;  3DDF A;  2LXY A;  3KDR A;  4EZO A;  3EJU A;  5C5B A;  4HY9 A;  2JNS A;  3RV0 A;  1JQK A;  1YWM A;  4F01 A;  4F00 A;  4EZQ A;  3G9G A;  3I2W A;  1DKY A;  2FYV A;  3I04 A;  3HAJ A;  3HAI A;  3EJT A;  4EZW A;  2FIC A;  2QFF A;  4FM3 A;  3B52 X;  1I49 A;  3EJQ A;  3LLL A;  1HXK A;  4JNF A;  3RPM A;  3D50 A;  4JNE A;  4AZG A;  2MI7 A;  1HWW A;  3DPQ A;  4IM2 A;  1R5E A;  2OBL A;  3L3O M;  2X5C A;  5E84 A;  3I01 A;  3EJS A;  2X3W A;  3KAW A;  3CZN A;  3L3P A;  1I4T A;  4AZC A;  4JWD A;  4HR1 B;  3VKH A;  4G6Q A;  3QNI A;  4IW0 A;  4EZS A;  4AZ5 A;  3D4Z A;  2N3K A;  2YLA A;  3BVV A;  1LQ7 A;  3DDG A;  4DYL A;  5KBP A;  2OO2 A;  3LMF A;  3B53 X;  1GNT A;  3Q0K A;  1DKZ A;  4AZ7 A;  3F7W A;  1X03 A;  3D2E A;  3O3N B;  2YL6 A;  3BUD A;  3BUP A;  1HTY A;  4EZR A;  1OAO A;  2X3X A;  4AZB A;  2D1L A;  2PY6 A;  2YIB A;  1R34 A;  3BVU A;  4IWP A;  2X3V A;  3A98 A;  3SYV A;  1X04 A;  3FD9 A;  3BUB A;  1E2U A;  4EZY A;  1UPX A;  1ZYL A;  2GA9 D;  2O0I 1;  3VEA A;  4JWE A;  1WDZ A;  4EZX A;  4DCN C;  3QE6 A;  2WIN M;  1QWU A;  1SU7 A;  3DX1 A;  3C7N A;  3T47 A; 
#chains in the Genus database with same CATH homology
 2Q12 A;  2RAK A;  3CAZ A;  3PLT A;  4H8S A;  3Q0K A;  3QNI A;  4WPE A;  3HAJ A;  3HAI A;  2EFK A;  2C08 A;  1X03 A;  3M3W A;  2RAI A;  3QWE A;  3DYT A;  2FIC A;  4BNE A;  4ATM A;  2Q13 A;  4I1Q A;  1ZWW A;  1URU A;  2YKT A;  5C5B A;  4AKV A;  2RAJ A;  1Y2O A;  2ELB A;  3ABH A;  3OK8 A;  2X3W A;  4WPC A;  3SOG A;  1I49 A;  1I4L A;  1WDZ A;  3LLL A;  3Q84 A;  4DCN C;  2X3X A;  3ACO A;  2D4C A;  4FZS A;  3QE6 A;  5C5B B;  4NSW A;  2D1L A;  2V0O A;  4AVM A;  1I4T A;  2EFL A;  2Z0O A;  3HAH A;  1I4D A;  4NQI A;  3G9G A;  4DYL A;  2X3V A;  2Z0V A;  3SYV A;  1X04 A;  3I2W A;  2Z0N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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