3ACOA

Crystal structure of the efc/f-bar domain of human pacsin2/syndapin ii (2.7 a)
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
284
structure length
284
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Protein kinase C and casein kinase substrate in neurons prot
publication title Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II
pubmed doi rcsb
source organism Homo sapiens
molecule tags Endocytosis
total genus 101
structure length 284
sequence length 284
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3acoA01
4DYLA 3QE6A 3PLTA 5C5BA 2YKTA 3QNIA 4WPCA 3SOGA 4FZSA 3HAHA 2Q12A 1ZWWA 4I1QA 5C5BB 1I4TA 2C08A 4AVMA 1URUA 2V0OA 2EFLA 4H8SA 2Z0OA 3DYTA 4ATMA 3I2WA 2X3VA 3G9GA 2D4CA 3LLLA 3QWEA 4NSWA 2EFKA 2FICA 3ACOA 3Q84A 2RAKA 4DCNC 1WDZA 2D1LA 3OK8A 4WPEA 2RAIA 4AKVA 3SYVA 1I4LA 3HAIA 2Q13A 4BNEA 3HAJA 3M3WA 1X03A 1Y2OA 2X3XA 3Q0KA 3CAZA 4NQIA 1I49A 2Z0NA 2X3WA 2RAJA 1I4DA 1X04A 2Z0VA 2ELBA 3ABHA
chains in the Genus database with same CATH superfamily
3PLTA 3ERCC 3EJRA 3LVTA 2YL9A 3T47A 4E81A 4FZOA 4JWDA 3CV5A 2YI8A 3CVRA 3DDGA 3Q0KA 3CAZA 3D2FA 3KAWA 3BUIA 1E1DA 1ZYLA 2PMRA 4B9QA 4JNFA 3I01A 4ATMA 4IM3A 2RAKA 4DCNC 2KHOA 4HR1B 3HAJA 1E2UA 1SU7A 4AZ5A 1OA1A 3BVTA 3T48A 2F1AA 4IM2A 3GI7A 1TQWA 2ND0A 3LLLA 4KIKB 3D2EA 2OZNB 3ACOA 4EZZA 4H6HA 2F7QA 4HR1A 1X04A 4EZQA 3D4ZA 3RV1A 2X5CA 2EFLA 1HWWA 5TKYA 2RAIA 2YI9A 3EJPA 2X3WA 4NPHA 5FLEX 4AZ7A 2LXYA 1SUFA 2PY6A 2YIAA 3D4YA 2NCZA 3CZSA 3D51A 2WINM 1QX1A 4EZWA 1I4DA 3B51X 3HAHA 4F01A 3ER9B 2D4CA 2YLAA 3DX3A 2FICA 3O3MB 3KAVA 3OK8A 4FZPA 1TQVA 3L3PA 3BVUA 3I39X 2OW7A 3L3OM 3DX4A 3ER8C 3ABHA 3QNIA 1PS3A 3ZEDA 4R5JA 2YLLA 3DYTA 3T49A 4AZHA 2O0I1 2F18A 2F7RA 3FD9A 2JNSA 1JQKA 4IW0A 2ND1A 3DPPA 4EZSA 4I1QA 3BLBA 3C7NA 3OWGA 4H8SA 3F7WA 3EJUA 4JWIA 2GF4A 3LMFA 1DKZA 1WDZA 1MJGA 4EZRA 4BNEA 2YIBA 2ELBA 4AZCA 2YIVX 3QE6A 4WPCA 1UPXA 3BUPA 3EJQA 1QWUA 1TQSA 3BVWA 4AZGA 3I2WA 3G9GA 3CKDA 2MI7A 1O7DC 4EZNA 1Y2OA 2QKWA 3BUQA 1SU6A 3I04A 2F1BA 2LM0A 3CZNA 2FYVA 1GNTA 2QXLA 3QA8A 2OW6A 4IWOA 3VEBA 4JWCA 3RV0A 2EFKA 4HY9A 4WPEA 4UDXX 3BUDA 1GNLA 2RAJA 2WYIA 3A98A 5C5BA 1LQ7A 1DKYA 3VKHA 3BVXA 2YL8A 5E84A 2OBMA 4R5IA 3DX2A 1HXKA 4EZVA 2ZXQA 3DPOA 2ALWA 3HAIA 3T46A 2N3KA 4M0MA 2JNKA 2Z0VA 3B53X 4H6IA 1OAOA 4JL9A 4NSWA 3BUBA 2EWFA 3Q84A 4E3CA 2Q13A 2EX3B 1W9MA 1YWMA 1X03A 4R5KA 4NQIA 1QWNA 2Z0NA 1GN9A 4AZCB 2YKTA 2RT6A 1ZWWA 1U00A 1I4TA 2QFFA 3EJTA 5FIGA 3DDFA 1URUA 2X3VA 2Z8YA 3QNJA 3DPQA 3RPMA 3O3NB 2D1LA 4FM3A 4IWQA 4HYBA 4EZOA 4EZPA 4EZXA 3VEAA 2YL5A 1R34A 4D8JA 3D52A 4R5GA 4AVMA 2V0OA 4AZ6A 1R33A 1DKXA 2F7OA 1E9VA 3QWEA 4IWPA 4EZYA 2WYHA 3SYVA 4AZBA 4UDYX 4EZTA 1I49A 1TQTA 3KDRA 2GAFD 4AZIA 3B52X 3O3OB 3SOGA 4FZSA 5C5BB 2Q12A 2OBLA 2Z0OA 3D50A 3DX1A 3OHXM 4KIKA 1OA0A 3T4AG 2OO2A 4AKVA 1R5EA 1I4LA 1O7DB 3UITA 4JN4A 2F7PA 4DYLA 1SU8A 4PO2A 1TQUA 2C08A 4EZUA 4F00A 2GA9D 3BVVA 4JNEA 3EJSA 2YL6A 3DX0A 4JWEA 4IM0A 1HTYA 3M3WA 2X3XA 4G6QA 4R5LA 4JLCA 5KBPA
chains in the Genus database with same CATH topology
4DYLA 3QE6A 3PLTA 5C5BA 2YKTA 3QNIA 4WPCA 3SOGA 4FZSA 3HAHA 2Q12A 1ZWWA 4I1QA 5C5BB 1I4TA 2C08A 4AVMA 1URUA 2V0OA 2EFLA 4H8SA 2Z0OA 3DYTA 4ATMA 3I2WA 2X3VA 3G9GA 2D4CA 3LLLA 3QWEA 4NSWA 2EFKA 2FICA 3ACOA 3Q84A 2RAKA 4DCNC 1WDZA 2D1LA 3OK8A 4WPEA 2RAIA 4AKVA 3SYVA 1I4LA 3HAIA 2Q13A 4BNEA 3HAJA 3M3WA 1X03A 1Y2OA 2X3XA 3Q0KA 3CAZA 4NQIA 1I49A 2Z0NA 2X3WA 2RAJA 1I4DA 1X04A 2Z0VA 2ELBA 3ABHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DYL A;  3QE6 A;  3PLT A;  5C5B A;  2YKT A;  3QNI A;  4WPC A;  3SOG A;  4FZS A;  3HAH A;  2Q12 A;  1ZWW A;  4I1Q A;  5C5B B;  1I4T A;  2C08 A;  4AVM A;  1URU A;  2V0O A;  2EFL A;  4H8S A;  2Z0O A;  3DYT A;  4ATM A;  3I2W A;  2X3V A;  3G9G A;  2D4C A;  3LLL A;  3QWE A;  4NSW A;  2EFK A;  2FIC A;  3ACO A;  3Q84 A;  2RAK A;  4DCN C;  1WDZ A;  2D1L A;  3OK8 A;  4WPE A;  2RAI A;  4AKV A;  3SYV A;  1I4L A;  3HAI A;  2Q13 A;  4BNE A;  3HAJ A;  3M3W A;  1X03 A;  1Y2O A;  2X3X A;  3Q0K A;  3CAZ A;  4NQI A;  1I49 A;  2Z0N A;  2X3W A;  2RAJ A;  1I4D A;  1X04 A;  2Z0V A;  2ELB A;  3ABH A; 
#chains in the Genus database with same CATH topology
 3PLT A;  3ERC C;  3EJR A;  3LVT A;  2YL9 A;  3T47 A;  4E81 A;  4FZO A;  4JWD A;  3CV5 A;  2YI8 A;  3CVR A;  3DDG A;  3Q0K A;  3CAZ A;  3D2F A;  3KAW A;  3BUI A;  1E1D A;  1ZYL A;  2PMR A;  4B9Q A;  4JNF A;  3I01 A;  4ATM A;  4IM3 A;  2RAK A;  4DCN C;  2KHO A;  4HR1 B;  3HAJ A;  1E2U A;  1SU7 A;  4AZ5 A;  1OA1 A;  3BVT A;  3T48 A;  2F1A A;  4IM2 A;  3GI7 A;  1TQW A;  2ND0 A;  3LLL A;  4KIK B;  3D2E A;  2OZN B;  3ACO A;  4EZZ A;  4H6H A;  2F7Q A;  4HR1 A;  1X04 A;  4EZQ A;  3D4Z A;  3RV1 A;  2X5C A;  2EFL A;  1HWW A;  5TKY A;  2RAI A;  2YI9 A;  3EJP A;  2X3W A;  4NPH A;  5FLE X;  4AZ7 A;  2LXY A;  1SUF A;  2PY6 A;  2YIA A;  3D4Y A;  2NCZ A;  3CZS A;  3D51 A;  2WIN M;  1QX1 A;  4EZW A;  1I4D A;  3B51 X;  3HAH A;  4F01 A;  3ER9 B;  2D4C A;  2YLA A;  3DX3 A;  2FIC A;  3O3M B;  3KAV A;  3OK8 A;  4FZP A;  1TQV A;  3L3P A;  3BVU A;  3I39 X;  2OW7 A;  3L3O M;  3DX4 A;  3ER8 C;  3ABH A;  3QNI A;  1PS3 A;  3ZED A;  4R5J A;  2YLL A;  3DYT A;  3T49 A;  4AZH A;  2O0I 1;  2F18 A;  2F7R A;  3FD9 A;  2JNS A;  1JQK A;  4IW0 A;  2ND1 A;  3DPP A;  4EZS A;  4I1Q A;  3BLB A;  3C7N A;  3OWG A;  4H8S A;  3F7W A;  3EJU A;  4JWI A;  2GF4 A;  3LMF A;  1DKZ A;  1WDZ A;  1MJG A;  4EZR A;  4BNE A;  2YIB A;  2ELB A;  4AZC A;  2YIV X;  3QE6 A;  4WPC A;  1UPX A;  3BUP A;  3EJQ A;  1QWU A;  1TQS A;  3BVW A;  4AZG A;  3I2W A;  3G9G A;  3CKD A;  2MI7 A;  1O7D C;  4EZN A;  1Y2O A;  2QKW A;  3BUQ A;  1SU6 A;  3I04 A;  2F1B A;  2LM0 A;  3CZN A;  2FYV A;  1GNT A;  2QXL A;  3QA8 A;  2OW6 A;  4IWO A;  3VEB A;  4JWC A;  3RV0 A;  2EFK A;  4HY9 A;  4WPE A;  4UDX X;  3BUD A;  1GNL A;  2RAJ A;  2WYI A;  3A98 A;  5C5B A;  1LQ7 A;  1DKY A;  3VKH A;  3BVX A;  2YL8 A;  5E84 A;  2OBM A;  4R5I A;  3DX2 A;  1HXK A;  4EZV A;  2ZXQ A;  3DPO A;  2ALW A;  3HAI A;  3T46 A;  2N3K A;  4M0M A;  2JNK A;  2Z0V A;  3B53 X;  4H6I A;  1OAO A;  4JL9 A;  4NSW A;  3BUB A;  2EWF A;  3Q84 A;  4E3C A;  2Q13 A;  2EX3 B;  1W9M A;  1YWM A;  1X03 A;  4R5K A;  4NQI A;  1QWN A;  2Z0N A;  1GN9 A;  4AZC B;  2YKT A;  2RT6 A;  1ZWW A;  1U00 A;  1I4T A;  2QFF A;  3EJT A;  5FIG A;  3DDF A;  1URU A;  2X3V A;  2Z8Y A;  3QNJ A;  3DPQ A;  3RPM A;  3O3N B;  2D1L A;  4FM3 A;  4IWQ A;  4HYB A;  4EZO A;  4EZP A;  4EZX A;  3VEA A;  2YL5 A;  1R34 A;  4D8J A;  3D52 A;  4R5G A;  4AVM A;  2V0O A;  4AZ6 A;  1R33 A;  1DKX A;  2F7O A;  1E9V A;  3QWE A;  4IWP A;  4EZY A;  2WYH A;  3SYV A;  4AZB A;  4UDY X;  4EZT A;  1I49 A;  1TQT A;  3KDR A;  2GAF D;  4AZI A;  3B52 X;  3O3O B;  3SOG A;  4FZS A;  5C5B B;  2Q12 A;  2OBL A;  2Z0O A;  3D50 A;  3DX1 A;  3OHX M;  4KIK A;  1OA0 A;  3T4A G;  2OO2 A;  4AKV A;  1R5E A;  1I4L A;  1O7D B;  3UIT A;  4JN4 A;  2F7P A;  4DYL A;  1SU8 A;  4PO2 A;  1TQU A;  2C08 A;  4EZU A;  4F00 A;  2GA9 D;  3BVV A;  4JNE A;  3EJS A;  2YL6 A;  3DX0 A;  4JWE A;  4IM0 A;  1HTY A;  3M3W A;  2X3X A;  4G6Q A;  4R5L A;  4JLC A;  5KBP A; 
#chains in the Genus database with same CATH homology
 4DYL A;  3QE6 A;  3PLT A;  5C5B A;  2YKT A;  3QNI A;  4WPC A;  3SOG A;  4FZS A;  3HAH A;  2Q12 A;  1ZWW A;  4I1Q A;  5C5B B;  1I4T A;  2C08 A;  4AVM A;  1URU A;  2V0O A;  2EFL A;  4H8S A;  2Z0O A;  3DYT A;  4ATM A;  3I2W A;  2X3V A;  3G9G A;  2D4C A;  3LLL A;  3QWE A;  4NSW A;  2EFK A;  2FIC A;  3ACO A;  3Q84 A;  2RAK A;  4DCN C;  1WDZ A;  2D1L A;  3OK8 A;  4WPE A;  2RAI A;  4AKV A;  3SYV A;  1I4L A;  3HAI A;  2Q13 A;  4BNE A;  3HAJ A;  3M3W A;  1X03 A;  1Y2O A;  2X3X A;  3Q0K A;  3CAZ A;  4NQI A;  1I49 A;  2Z0N A;  2X3W A;  2RAJ A;  1I4D A;  1X04 A;  2Z0V A;  2ELB A;  3ABH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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