3AJVB

Splicing endonuclease from aeropyrum pernix
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
180
structure length
180
Chain Sequence
PIKASGVLIGDSVLVTDVEQARSLYSCGYYGQPLDVEKPRGADFEGPLRLSLIESLYLAEKGVLEVAKPDGSSVGVEDLRTAVRGNPRFSMLYNIYRDLRERGFVVRSGLKFGSDFAVYRLGPGIDAAPFIVHAYSPEDNIDPVEIVRAGRLSHSVRKKFVFAVTRGGDVSYLMIDWFRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Conserved Lysine Residue in the Crenarchaea-Specific Loop is Important for the Crenarchaeal Splicing Endonuclease Activity.
pubmed doi rcsb
molecule tags Hydrolase
source organism Aeropyrum pernix
molecule keywords Putative uncharacterized protein
total genus 52
structure length 180
sequence length 180
chains with identical sequence D
ec nomenclature ec 4.6.1.16: tRNA-intron lyase.
pdb deposition date 2010-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
B PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 3ajvB01
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 3ajvB02
4FZ2A 2ZYZB 3P1ZB 1XMXA 2VLDA 2GW6A 4TKDA 3AJVA 2WCWA 1RLVA 2WCZA 1RZNA 1Y88A 4QBOA 3IEYA 1F1ZA 2ZYZA 3P1ZA 1R0VA 2OKFA 3DNXA 1HH1A 1OB9A 2CV8A 1ZP7A 2WIWA 1R11A 1T0FA 1Y1OA 3FOVA 2INBA 2OSTA 2FCOA 2GJWA 2EO0A 2WJ0A 2WIZA 4QBLA 1OB8A 3AJVB 1GEFA 4QBNA 1IPIA 5FDKA 1A79A 4TKKA 3P1YA
chains in the Genus database with same CATH superfamily
1EWQA 4G6VA 1WBDA 2WTUA 3K0SA 3AJVA 1NNEA 4DA2A 3THYB 1FW6A 1RZNA 1Y88A 2O8CA 2FZ4A 2O8BB 2FL3A 3FOVA 2INBA 2EO0A 2O8DB 4QBNA 3THXB 1IPIA 5FDKA 4TKKA 2ZYZB 3P1ZB 1XMXA 2GW6A 2FKHB 2Z0RA 4QBOA 2FWRA 2O8FA 1YNMA 3ZLJA 3DNXA 2CV8A 2W8MA 1WB9A 2WIWA 4LQEA 4E6ZA 1T0FA 2O8EA 1E3MA 2GJWA 4QBLA 3BT7A 3AJVB 3IF0X 3IEYA 3P1YA 4FZ2A 1NG9A 2VLDA 2BH2A 1RLVA 1OH6A 1UWVA 2DBSA 2O8CB 3THYA 1WBBA 1HH1A 1OB9A 1R11A 1Y1OA 4EV1A 3THWA 2FCOA 2WJ0A 2WIZA 2O8BA 1GEFA 1OH8A 1A79A 1OH5A 2IXSA 4DAVA 2O8DA 2O8FB 2FKCA 4TKDA 2WCWA 3THXA 2WCZA 1F1ZA 2ZYZA 3P1ZA 4G6UA 1R0VA 3THWB 2O8EB 2OKFA 1OH7A 1ZP7A 2FLCA 2OSTA 3IEYB 2CZRA 2JJQA 1W7AA 1OB8A 2VS1A 4DAPA 4ZQUA
chains in the Genus database with same CATH topology
4DAVA 4G6VA 4FZ2A 2ZYZB 2FKCA 3P1ZB 1XMXA 2VLDA 2GW6A 4TKDA 3AJVA 2WCWA 4DA2A 2BH2A 1RLVA 2WCZA 1RZNA 2FKHB 2Z0RA 1Y88A 4QBOA 1UWVA 2DBSA 3IEYA 1F1ZA 2ZYZA 3P1ZA 4G6UA 1R0VA 1YNMA 2OKFA 3DNXA 1HH1A 1OB9A 2CV8A 1ZP7A 2W8MA 2WIWA 1R11A 4LQEA 4E6ZA 1T0FA 2FL3A 1Y1OA 3FOVA 2FLCA 2INBA 4EV1A 2OSTA 2FCOA 2GJWA 3IEYB 2EO0A 2CZRA 2JJQA 2WIZA 2WJ0A 4QBLA 1OB8A 2VS1A 3BT7A 3AJVB 4TKKA 1GEFA 4QBNA 4ZQUA 4DAPA 1IPIA 5FDKA 1A79A 2IXSA 3IF0X 3P1YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FZ2 A;  2ZYZ B;  3P1Z B;  1XMX A;  2VLD A;  2GW6 A;  4TKD A;  3AJV A;  2WCW A;  1RLV A;  2WCZ A;  1RZN A;  1Y88 A;  4QBO A;  3IEY A;  1F1Z A;  2ZYZ A;  3P1Z A;  1R0V A;  2OKF A;  3DNX A;  1HH1 A;  1OB9 A;  2CV8 A;  1ZP7 A;  2WIW A;  1R11 A;  1T0F A;  1Y1O A;  3FOV A;  2INB A;  2OST A;  2FCO A;  2GJW A;  2EO0 A;  2WJ0 A;  2WIZ A;  4QBL A;  1OB8 A;  3AJV B;  1GEF A;  4QBN A;  1IPI A;  5FDK A;  1A79 A;  4TKK A;  3P1Y A; 
#chains in the Genus database with same CATH topology
 1EWQ A;  4G6V A;  1WBD A;  2WTU A;  3K0S A;  3AJV A;  1NNE A;  4DA2 A;  3THY B;  1FW6 A;  1RZN A;  1Y88 A;  2O8C A;  2FZ4 A;  2O8B B;  2FL3 A;  3FOV A;  2INB A;  2EO0 A;  2O8D B;  4QBN A;  3THX B;  1IPI A;  5FDK A;  4TKK A;  2ZYZ B;  3P1Z B;  1XMX A;  2GW6 A;  2FKH B;  2Z0R A;  4QBO A;  2FWR A;  2O8F A;  1YNM A;  3ZLJ A;  3DNX A;  2CV8 A;  2W8M A;  1WB9 A;  2WIW A;  4LQE A;  4E6Z A;  1T0F A;  2O8E A;  1E3M A;  2GJW A;  4QBL A;  3BT7 A;  3AJV B;  3IF0 X;  3IEY A;  3P1Y A;  4FZ2 A;  1NG9 A;  2VLD A;  2BH2 A;  1RLV A;  1OH6 A;  1UWV A;  2DBS A;  2O8C B;  3THY A;  1WBB A;  1HH1 A;  1OB9 A;  1R11 A;  1Y1O A;  4EV1 A;  3THW A;  2FCO A;  2WJ0 A;  2WIZ A;  2O8B A;  1GEF A;  1OH8 A;  1A79 A;  1OH5 A;  2IXS A;  4DAV A;  2O8D A;  2O8F B;  2FKC A;  4TKD A;  2WCW A;  3THX A;  2WCZ A;  1F1Z A;  2ZYZ A;  3P1Z A;  4G6U A;  1R0V A;  3THW B;  2O8E B;  2OKF A;  1OH7 A;  1ZP7 A;  2FLC A;  2OST A;  3IEY B;  2CZR A;  2JJQ A;  1W7A A;  1OB8 A;  2VS1 A;  4DAP A;  4ZQU A; 
#chains in the Genus database with same CATH homology
 4DAV A;  4G6V A;  4FZ2 A;  2ZYZ B;  2FKC A;  3P1Z B;  1XMX A;  2VLD A;  2GW6 A;  4TKD A;  3AJV A;  2WCW A;  4DA2 A;  2BH2 A;  1RLV A;  2WCZ A;  1RZN A;  2FKH B;  2Z0R A;  1Y88 A;  4QBO A;  1UWV A;  2DBS A;  3IEY A;  1F1Z A;  2ZYZ A;  3P1Z A;  4G6U A;  1R0V A;  1YNM A;  2OKF A;  3DNX A;  1HH1 A;  1OB9 A;  2CV8 A;  1ZP7 A;  2W8M A;  2WIW A;  1R11 A;  4LQE A;  4E6Z A;  1T0F A;  2FL3 A;  1Y1O A;  3FOV A;  2FLC A;  2INB A;  4EV1 A;  2OST A;  2FCO A;  2GJW A;  3IEY B;  2EO0 A;  2CZR A;  2JJQ A;  2WIZ A;  2WJ0 A;  4QBL A;  1OB8 A;  2VS1 A;  3BT7 A;  3AJV B;  4TKK A;  1GEF A;  4QBN A;  4ZQU A;  4DAP A;  1IPI A;  5FDK A;  1A79 A;  2IXS A;  3IF0 X;  3P1Y A; 
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