3ALQR

Crystal structure of tnf-tnfr2 complex
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
162
structure length
162
Chain Sequence
TCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cytokine/cytokine receptor
molecule keywords Tumor necrosis factor
publication title Solution of the Structure of the TNF-TNFR2 Complex
pubmed doi rcsb
source organism Homo sapiens
total genus 25
structure length 162
sequence length 162
chains with identical sequence S, T, U, V, W
ec nomenclature
pdb deposition date 2010-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 3alqR02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 3alqR01
2HEVR 3X3FA 4GIQR 4I9XC 1NCFA 5CIRE 4J6GC 5L36B 3URFZ 4MSVB 4M4RA 4KGQC 3ALQR 1TNRR 1JMAB 1D0GR 3MBWA 1DU3A 3TJEF 4E4DR 5BNQR 3U3PA 1SG1X 2UWIA 4KGGC 3ME4A 3U3QA 3MI8D 2H9GR 3FL7A 4OD2S 2X10A 3QD6R 1ZA3R 3U3SA 5DMJA 3U3TA 4YN0A 3K51B 1FT4A 3MHDD 3IJ2X 3WVTA 3QO4A 1EXTA 3ME2R 2HEYR 4N90R 1D4VA 4MXWR 3THMF 3BUKC 3QBQB 5IHLA 4BK4A 2AW2B 4M4PA 4FHQA 4RSUD 3U3VA 4BK5A
chains in the Genus database with same CATH superfamily
2HEVR 3X3FA 2QR6A 4GIQR 4I9XC 1NCFA 4FHQA 4J6GC 5CIRE 5L36B 3URFZ 4MSVB 4M4RA 4KGQC 3ALQR 1TNRR 1JMAB 1D0GR 3MBWA 1DU3A 3TJEF 4E4DR 5BNQR 2E4UA 3U3PA 1SG1X 2UWIA 4KGGC 3ME4A 3U3QA 3MI8D 2H9GR 3FL7A 4OD2S 2X10A 3QD6R 1ZA3R 3U3SA 2E4VA 5DMJA 3U3TA 4YN0A 3K51B 1FT4A 3MHDD 3IJ2X 2E4YA 3WVTA 3QO4A 1EXTA 3ME2R 2E4WA 2HEYR 4N90R 1D4VA 4MXWR 3THMF 3BUKC 3QBQB 5IHLA 4BK4A 2AW2B 4M4PA 2E4XA 4RSUD 3U3VA 4BK5A
chains in the Genus database with same CATH topology
2HEVR 3X3FA 4GIQR 4I9XC 1NCFA 5CIRE 4J6GC 5L36B 3URFZ 4MSVB 4M4RA 4KGQC 3ALQR 1TNRR 1JMAB 1D0GR 3MBWA 1DU3A 3TJEF 4E4DR 5BNQR 3U3PA 1SG1X 2UWIA 4KGGC 3ME4A 3U3QA 3MI8D 2H9GR 3FL7A 4OD2S 2X10A 3QD6R 1ZA3R 3U3SA 5DMJA 3U3TA 4YN0A 3K51B 1FT4A 3MHDD 3IJ2X 3WVTA 3QO4A 1EXTA 3ME2R 2HEYR 4N90R 1D4VA 4MXWR 3THMF 3BUKC 3QBQB 5IHLA 4BK4A 2AW2B 4M4PA 4FHQA 4RSUD 3U3VA 4BK5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HEV R;  3X3F A;  4GIQ R;  4I9X C;  1NCF A;  5CIR E;  4J6G C;  5L36 B;  3URF Z;  4MSV B;  4M4R A;  4KGQ C;  3ALQ R;  1TNR R;  1JMA B;  1D0G R;  3MBW A;  1DU3 A;  3TJE F;  4E4D R;  5BNQ R;  3U3P A;  1SG1 X;  2UWI A;  4KGG C;  3ME4 A;  3U3Q A;  3MI8 D;  2H9G R;  3FL7 A;  4OD2 S;  2X10 A;  3QD6 R;  1ZA3 R;  3U3S A;  5DMJ A;  3U3T A;  4YN0 A;  3K51 B;  1FT4 A;  3MHD D;  3IJ2 X;  3WVT A;  3QO4 A;  1EXT A;  3ME2 R;  2HEY R;  4N90 R;  1D4V A;  4MXW R;  3THM F;  3BUK C;  3QBQ B;  5IHL A;  4BK4 A;  2AW2 B;  4M4P A;  4FHQ A;  4RSU D;  3U3V A;  4BK5 A; 
#chains in the Genus database with same CATH topology
 2HEV R;  3X3F A;  2QR6 A;  4GIQ R;  4I9X C;  1NCF A;  4FHQ A;  4J6G C;  5CIR E;  5L36 B;  3URF Z;  4MSV B;  4M4R A;  4KGQ C;  3ALQ R;  1TNR R;  1JMA B;  1D0G R;  3MBW A;  1DU3 A;  3TJE F;  4E4D R;  5BNQ R;  2E4U A;  3U3P A;  1SG1 X;  2UWI A;  4KGG C;  3ME4 A;  3U3Q A;  3MI8 D;  2H9G R;  3FL7 A;  4OD2 S;  2X10 A;  3QD6 R;  1ZA3 R;  3U3S A;  2E4V A;  5DMJ A;  3U3T A;  4YN0 A;  3K51 B;  1FT4 A;  3MHD D;  3IJ2 X;  2E4Y A;  3WVT A;  3QO4 A;  1EXT A;  3ME2 R;  2E4W A;  2HEY R;  4N90 R;  1D4V A;  4MXW R;  3THM F;  3BUK C;  3QBQ B;  5IHL A;  4BK4 A;  2AW2 B;  4M4P A;  2E4X A;  4RSU D;  3U3V A;  4BK5 A; 
#chains in the Genus database with same CATH homology
 2HEV R;  3X3F A;  4GIQ R;  4I9X C;  1NCF A;  5CIR E;  4J6G C;  5L36 B;  3URF Z;  4MSV B;  4M4R A;  4KGQ C;  3ALQ R;  1TNR R;  1JMA B;  1D0G R;  3MBW A;  1DU3 A;  3TJE F;  4E4D R;  5BNQ R;  3U3P A;  1SG1 X;  2UWI A;  4KGG C;  3ME4 A;  3U3Q A;  3MI8 D;  2H9G R;  3FL7 A;  4OD2 S;  2X10 A;  3QD6 R;  1ZA3 R;  3U3S A;  5DMJ A;  3U3T A;  4YN0 A;  3K51 B;  1FT4 A;  3MHD D;  3IJ2 X;  3WVT A;  3QO4 A;  1EXT A;  3ME2 R;  2HEY R;  4N90 R;  1D4V A;  4MXW R;  3THM F;  3BUK C;  3QBQ B;  5IHL A;  4BK4 A;  2AW2 B;  4M4P A;  4FHQ A;  4RSU D;  3U3V A;  4BK5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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