3ANZA

Crystal structure of alpha-hemolysin
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
295
structure length
295
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTNLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Alpha-hemolysin
publication title 2-Methyl-2,4-pentanediol induces spontaneous assembly of staphylococcal alpha-hemolysin into heptameric pore structure
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 63
structure length 295
sequence length 295
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b
ec nomenclature
pdb deposition date 2010-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 3anzA00
2YGTA 5K59C 7AHLA 3M4EA 3B07B 4U6VA 4P1YB 3ANZA 4TW1A 2LKFA 4I0NA 2QK7A 1LKFA 1PVLA 3LKFA 4IYCA 4P1XA 3M4DA 4IDJA 3ROHA 4YHDA 4H56A 4IYAA 4P24A 3B07A 4IZLA 4J0OA 1T5RA 4TW1B 5K59A 4P1YA 4Q7GA 2QK7B 4IYTA 3M2LA 4P1XB 3O44A 3M3RA
chains in the Genus database with same CATH superfamily
2YGTA 5K59C 7AHLA 3M4EA 3B07B 4U6VA 4P1YB 3ANZA 4TW1A 2LKFA 4I0NA 2QK7A 1LKFA 1PVLA 1XEZA 3LKFA 4IYCA 4P1XA 3M4DA 4IDJA 3ROHA 4YHDA 4H56A 4IYAA 4P24A 3B07A 4IZLA 4J0OA 1T5RA 4TW1B 5K59A 4P1YA 4Q7GA 2QK7B 4IYTA 3M2LA 4P1XB 3O44A 3M3RA
chains in the Genus database with same CATH topology
2YGTA 5K59C 7AHLA 3M4EA 3B07B 4U6VA 4P1YB 3ANZA 4TW1A 2LKFA 4I0NA 2QK7A 1LKFA 1PVLA 3LKFA 4IYCA 4P1XA 3M4DA 4IDJA 3ROHA 4YHDA 4H56A 4IYAA 4P24A 3B07A 4IZLA 4J0OA 1T5RA 4TW1B 5K59A 4P1YA 4Q7GA 2QK7B 4IYTA 3M2LA 4P1XB 3O44A 3M3RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YGT A;  5K59 C;  7AHL A;  3M4E A;  3B07 B;  4U6V A;  4P1Y B;  3ANZ A;  4TW1 A;  2LKF A;  4I0N A;  2QK7 A;  1LKF A;  1PVL A;  3LKF A;  4IYC A;  4P1X A;  3M4D A;  4IDJ A;  3ROH A;  4YHD A;  4H56 A;  4IYA A;  4P24 A;  3B07 A;  4IZL A;  4J0O A;  1T5R A;  4TW1 B;  5K59 A;  4P1Y A;  4Q7G A;  2QK7 B;  4IYT A;  3M2L A;  4P1X B;  3O44 A;  3M3R A; 
#chains in the Genus database with same CATH topology
 2YGT A;  5K59 C;  7AHL A;  3M4E A;  3B07 B;  4U6V A;  4P1Y B;  3ANZ A;  4TW1 A;  2LKF A;  4I0N A;  2QK7 A;  1LKF A;  1PVL A;  1XEZ A;  3LKF A;  4IYC A;  4P1X A;  3M4D A;  4IDJ A;  3ROH A;  4YHD A;  4H56 A;  4IYA A;  4P24 A;  3B07 A;  4IZL A;  4J0O A;  1T5R A;  4TW1 B;  5K59 A;  4P1Y A;  4Q7G A;  2QK7 B;  4IYT A;  3M2L A;  4P1X B;  3O44 A;  3M3R A; 
#chains in the Genus database with same CATH homology
 2YGT A;  5K59 C;  7AHL A;  3M4E A;  3B07 B;  4U6V A;  4P1Y B;  3ANZ A;  4TW1 A;  2LKF A;  4I0N A;  2QK7 A;  1LKF A;  1PVL A;  3LKF A;  4IYC A;  4P1X A;  3M4D A;  4IDJ A;  3ROH A;  4YHD A;  4H56 A;  4IYA A;  4P24 A;  3B07 A;  4IZL A;  4J0O A;  1T5R A;  4TW1 B;  5K59 A;  4P1Y A;  4Q7G A;  2QK7 B;  4IYT A;  3M2L A;  4P1X B;  3O44 A;  3M3R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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